EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000020850 (Gene tree)
Gene ID: 192159
Gene Symbol: Prpf8
Alias: D11Bwg0410e|DBF3/PRP8|Prp8|Sfprp8l
Full Name: pre-mRNA processing factor 8
Gene Type: protein_coding
Species: Mus_musculus
Status: confidence
Strand: Plus strand
Length: 22634 bases
Position: chr11:75486816-75509449
Accession: 2179381
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000115635	RRM_4	PF10598.9	2.9e-48	1	1
ENSMUSP00000018449	RRM_4	PF10598.9	7.6e-48	1	1
ENSMUSP00000099568	RRM_4	PF10598.9	7.6e-48	1	1
ENSMUSP00000018449	U5_2-snRNA_bdg	PF10597.9	1.5e-73	1	1
ENSMUSP00000099568	U5_2-snRNA_bdg	PF10597.9	1.5e-73	1	1
ENSMUSP00000018449	PRO8NT	PF08082.11	3e-86	1	1
ENSMUSP00000099568	PRO8NT	PF08082.11	3e-86	1	1
ENSMUSP00000115635	PRO8NT	PF08082.11	3.9e-43	1	2
ENSMUSP00000115635	PRO8NT	PF08082.11	3.9e-43	2	2
ENSMUSP00000018449	U6-snRNA_bdg	PF10596.9	3.6e-89	1	1
ENSMUSP00000099568	U6-snRNA_bdg	PF10596.9	3.6e-89	1	1
ENSMUSP00000115635	PROCN	PF08083.11	6.6e-236	1	1
ENSMUSP00000018449	PROCN	PF08083.11	3.9e-235	1	1
ENSMUSP00000099568	PROCN	PF08083.11	3.9e-235	1	1
ENSMUSP00000018449	PRP8_domainIV	PF12134.8	6.8e-130	1	1
ENSMUSP00000099568	PRP8_domainIV	PF12134.8	6.8e-130	1	1
ENSMUSP00000018449	PROCT	PF08084.11	3.1e-53	1	1
ENSMUSP00000099568	PROCT	PF08084.11	3.1e-53	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
25993413	Label-Free Protein RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression	IC & MEF	2015	Boucas J	DOI: 10.1371/journal.pone.0125745
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000102510	-	7249	-	ENSMUSP00000099568	2335 (aa)	-	Q99PV0
ENSMUST00000131283	-	3371	-	ENSMUSP00000115635	1044 (aa)	-	B7ZC27
ENSMUST00000018449	-	7442	-	ENSMUSP00000018449	2335 (aa)	-	Q99PV0
ENSMUST00000133995	-	721	-	-	- (aa)	-	-

Gene Model

Click here to download ENSMUSG00000020850's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu03040	Spliceosome	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000020850's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000020850	Prpf8	100	99.914	ENSG00000174231	PRPF8	100	100.000	Homo_sapiens
ENSMUSG00000020850	Prpf8	100	97.777	ENSAPOG00000010079	prpf8	100	97.777	Acanthochromis_polyacanthus
ENSMUSG00000020850	Prpf8	100	99.914	ENSAMEG00000007940	PRPF8	100	99.914	Ailuropoda_melanoleuca
ENSMUSG00000020850	Prpf8	100	95.507	ENSACIG00000018280	prpf8	100	95.883	Amphilophus_citrinellus
ENSMUSG00000020850	Prpf8	100	97.777	ENSAOCG00000010725	prpf8	100	97.777	Amphiprion_ocellaris
ENSMUSG00000020850	Prpf8	100	97.777	ENSAPEG00000014397	prpf8	100	97.777	Amphiprion_percula
ENSMUSG00000020850	Prpf8	100	97.220	ENSATEG00000010062	prpf8	100	97.220	Anabas_testudineus
ENSMUSG00000020850	Prpf8	96	99.466	ENSAPLG00000010357	PRPF8	100	99.466	Anas_platyrhynchos
ENSMUSG00000020850	Prpf8	99	93.460	ENSACAG00000014784	PRPF8	99	97.477	Anolis_carolinensis
ENSMUSG00000020850	Prpf8	100	99.914	ENSANAG00000032629	PRPF8	100	99.914	Aotus_nancymaae
ENSMUSG00000020850	Prpf8	100	97.404	ENSACLG00000020858	prpf8	100	97.404	Astatotilapia_calliptera
ENSMUSG00000020850	Prpf8	100	97.688	ENSAMXG00000020291	prpf8	100	97.688	Astyanax_mexicanus
ENSMUSG00000020850	Prpf8	100	99.914	ENSBTAG00000011488	PRPF8	100	99.914	Bos_taurus
ENSMUSG00000020850	Prpf8	99	86.401	WBGene00004187	prp-8	99	86.486	Caenorhabditis_elegans
ENSMUSG00000020850	Prpf8	100	99.914	ENSCJAG00000001911	PRPF8	100	99.914	Callithrix_jacchus
ENSMUSG00000020850	Prpf8	100	99.914	ENSCAFG00000019221	PRPF8	100	99.914	Canis_familiaris
ENSMUSG00000020850	Prpf8	96	99.911	ENSCAFG00020009943	PRPF8	100	99.911	Canis_lupus_dingo
ENSMUSG00000020850	Prpf8	100	99.914	ENSCHIG00000017499	PRPF8	100	99.914	Capra_hircus
ENSMUSG00000020850	Prpf8	100	99.914	ENSTSYG00000014120	PRPF8	100	99.914	Carlito_syrichta
ENSMUSG00000020850	Prpf8	96	97.684	ENSCAPG00000009459	PRPF8	99	97.684	Cavia_aperea
ENSMUSG00000020850	Prpf8	100	99.914	ENSCPOG00000010379	PRPF8	100	99.914	Cavia_porcellus
ENSMUSG00000020850	Prpf8	100	99.914	ENSCCAG00000031983	-	100	99.914	Cebus_capucinus
ENSMUSG00000020850	Prpf8	100	99.914	ENSCATG00000038595	PRPF8	100	99.914	Cercocebus_atys
ENSMUSG00000020850	Prpf8	100	99.914	ENSCLAG00000004388	PRPF8	100	99.914	Chinchilla_lanigera
ENSMUSG00000020850	Prpf8	100	99.914	ENSCSAG00000013929	PRPF8	100	99.914	Chlorocebus_sabaeus
ENSMUSG00000020850	Prpf8	81	99.738	ENSCHOG00000008590	PRPF8	88	99.738	Choloepus_hoffmanni
ENSMUSG00000020850	Prpf8	100	99.443	ENSCPBG00000020409	PRPF8	100	99.443	Chrysemys_picta_bellii
ENSMUSG00000020850	Prpf8	99	92.874	ENSCSAVG00000007825	-	100	91.237	Ciona_savignyi
ENSMUSG00000020850	Prpf8	100	99.914	ENSCANG00000043088	PRPF8	100	99.914	Colobus_angolensis_palliatus
ENSMUSG00000020850	Prpf8	92	94.510	ENSCGRG00001017673	-	98	100.000	Cricetulus_griseus_chok1gshd
ENSMUSG00000020850	Prpf8	78	99.753	ENSCGRG00000005129	Prpf8	100	99.533	Cricetulus_griseus_crigri
ENSMUSG00000020850	Prpf8	100	97.606	ENSCSEG00000007905	prpf8	100	97.606	Cynoglossus_semilaevis
ENSMUSG00000020850	Prpf8	100	97.566	ENSDARG00000026180	prpf8	100	97.566	Danio_rerio
ENSMUSG00000020850	Prpf8	100	94.904	ENSDNOG00000018471	PRPF8	99	99.862	Dasypus_novemcinctus
ENSMUSG00000020850	Prpf8	100	94.219	ENSDORG00000006185	Prpf8	96	99.432	Dipodomys_ordii
ENSMUSG00000020850	Prpf8	99	91.506	FBgn0033688	Prp8	98	91.080	Drosophila_melanogaster
ENSMUSG00000020850	Prpf8	100	94.433	ENSETEG00000017592	PRPF8	100	94.433	Echinops_telfairi
ENSMUSG00000020850	Prpf8	99	93.771	ENSEBUG00000006548	prpf8	99	93.771	Eptatretus_burgeri
ENSMUSG00000020850	Prpf8	100	99.914	ENSEASG00005009514	PRPF8	100	99.914	Equus_asinus_asinus
ENSMUSG00000020850	Prpf8	97	99.912	ENSECAG00000021318	PRPF8	100	99.912	Equus_caballus
ENSMUSG00000020850	Prpf8	67	100.000	ENSEEUG00000012120	-	67	100.000	Erinaceus_europaeus
ENSMUSG00000020850	Prpf8	98	96.503	ENSELUG00000007120	prpf8	99	96.503	Esox_lucius
ENSMUSG00000020850	Prpf8	100	99.914	ENSFCAG00000006297	PRPF8	100	99.914	Felis_catus
ENSMUSG00000020850	Prpf8	100	99.400	ENSFALG00000006628	PRPF8	100	99.400	Ficedula_albicollis
ENSMUSG00000020850	Prpf8	100	99.914	ENSFDAG00000004711	PRPF8	100	99.914	Fukomys_damarensis
ENSMUSG00000020850	Prpf8	100	97.395	ENSFHEG00000021084	prpf8	100	97.395	Fundulus_heteroclitus
ENSMUSG00000020850	Prpf8	100	95.347	ENSGMOG00000002028	prpf8	99	95.347	Gadus_morhua
ENSMUSG00000020850	Prpf8	100	99.358	ENSGALG00000002943	PRPF8	100	99.358	Gallus_gallus
ENSMUSG00000020850	Prpf8	99	97.478	ENSGAFG00000010337	prpf8	99	97.478	Gambusia_affinis
ENSMUSG00000020850	Prpf8	100	97.473	ENSGACG00000008504	prpf8	100	97.473	Gasterosteus_aculeatus
ENSMUSG00000020850	Prpf8	100	99.443	ENSGAGG00000008350	PRPF8	100	99.443	Gopherus_agassizii
ENSMUSG00000020850	Prpf8	100	99.914	ENSGGOG00000005516	PRPF8	100	99.914	Gorilla_gorilla
ENSMUSG00000020850	Prpf8	100	97.561	ENSHBUG00000016192	prpf8	100	97.561	Haplochromis_burtoni
ENSMUSG00000020850	Prpf8	100	99.914	ENSHGLG00000012029	PRPF8	100	99.914	Heterocephalus_glaber_female
ENSMUSG00000020850	Prpf8	100	99.914	ENSHGLG00100016494	PRPF8	100	99.914	Heterocephalus_glaber_male
ENSMUSG00000020850	Prpf8	100	97.520	ENSHCOG00000016414	prpf8	100	97.520	Hippocampus_comes
ENSMUSG00000020850	Prpf8	100	97.562	ENSIPUG00000023230	prpf8	100	97.562	Ictalurus_punctatus
ENSMUSG00000020850	Prpf8	100	99.914	ENSSTOG00000005128	PRPF8	100	99.914	Ictidomys_tridecemlineatus
ENSMUSG00000020850	Prpf8	100	97.816	ENSJJAG00000021159	Prpf8	100	97.816	Jaculus_jaculus
ENSMUSG00000020850	Prpf8	99	97.934	ENSKMAG00000016118	prpf8	99	97.934	Kryptolebias_marmoratus
ENSMUSG00000020850	Prpf8	100	97.435	ENSLBEG00000026903	prpf8	100	97.435	Labrus_bergylta
ENSMUSG00000020850	Prpf8	100	91.985	ENSLACG00000010479	PRPF8	99	98.502	Latimeria_chalumnae
ENSMUSG00000020850	Prpf8	99	97.688	ENSLOCG00000005409	prpf8	99	97.688	Lepisosteus_oculatus
ENSMUSG00000020850	Prpf8	100	99.914	ENSLAFG00000015445	PRPF8	100	99.914	Loxodonta_africana
ENSMUSG00000020850	Prpf8	100	99.914	ENSMFAG00000039995	PRPF8	100	99.914	Macaca_fascicularis
ENSMUSG00000020850	Prpf8	100	99.914	ENSMMUG00000004820	PRPF8	100	99.914	Macaca_mulatta
ENSMUSG00000020850	Prpf8	100	99.914	ENSMNEG00000035713	PRPF8	100	99.914	Macaca_nemestrina
ENSMUSG00000020850	Prpf8	100	99.914	ENSMLEG00000037937	PRPF8	100	99.914	Mandrillus_leucophaeus
ENSMUSG00000020850	Prpf8	100	97.733	ENSMAMG00000008919	prpf8	100	97.733	Mastacembelus_armatus
ENSMUSG00000020850	Prpf8	100	97.404	ENSMZEG00005015073	prpf8	100	97.404	Maylandia_zebra
ENSMUSG00000020850	Prpf8	100	99.358	ENSMGAG00000004769	PRPF8	100	99.358	Meleagris_gallopavo
ENSMUSG00000020850	Prpf8	100	99.957	ENSMICG00000010320	PRPF8	100	99.957	Microcebus_murinus
ENSMUSG00000020850	Prpf8	100	99.957	ENSMOCG00000016838	Prpf8	100	99.957	Microtus_ochrogaster
ENSMUSG00000020850	Prpf8	100	97.263	ENSMMOG00000011887	prpf8	100	97.263	Mola_mola
ENSMUSG00000020850	Prpf8	100	99.743	ENSMODG00000010480	PRPF8	100	99.743	Monodelphis_domestica
ENSMUSG00000020850	Prpf8	97	97.621	ENSMALG00000003558	prpf8	100	97.621	Monopterus_albus
ENSMUSG00000020850	Prpf8	100	100.000	MGP_CAROLIEiJ_G0016740	Prpf8	100	100.000	Mus_caroli
ENSMUSG00000020850	Prpf8	100	99.914	MGP_PahariEiJ_G0017877	Prpf8	100	99.914	Mus_pahari
ENSMUSG00000020850	Prpf8	100	100.000	MGP_SPRETEiJ_G0017583	Prpf8	100	100.000	Mus_spretus
ENSMUSG00000020850	Prpf8	100	99.914	ENSMPUG00000013227	PRPF8	100	99.914	Mustela_putorius_furo
ENSMUSG00000020850	Prpf8	100	99.743	ENSMLUG00000002666	PRPF8	100	99.743	Myotis_lucifugus
ENSMUSG00000020850	Prpf8	100	98.201	ENSNGAG00000005305	Prpf8	100	98.201	Nannospalax_galili
ENSMUSG00000020850	Prpf8	100	97.447	ENSNBRG00000013127	prpf8	100	97.447	Neolamprologus_brichardi
ENSMUSG00000020850	Prpf8	97	97.570	ENSNLEG00000000897	PRPF8	98	97.570	Nomascus_leucogenys
ENSMUSG00000020850	Prpf8	99	97.957	ENSMEUG00000015999	PRPF8	100	97.957	Notamacropus_eugenii
ENSMUSG00000020850	Prpf8	100	98.458	ENSOPRG00000003102	PRPF8	100	98.458	Ochotona_princeps
ENSMUSG00000020850	Prpf8	100	99.914	ENSODEG00000008468	PRPF8	100	99.914	Octodon_degus
ENSMUSG00000020850	Prpf8	100	97.448	ENSONIG00000008153	prpf8	100	97.448	Oreochromis_niloticus
ENSMUSG00000020850	Prpf8	82	99.645	ENSOANG00000004250	PRPF8	97	99.645	Ornithorhynchus_anatinus
ENSMUSG00000020850	Prpf8	100	99.914	ENSOCUG00000000081	PRPF8	100	99.914	Oryctolagus_cuniculus
ENSMUSG00000020850	Prpf8	99	97.645	ENSORLG00000008036	prpf8	99	97.645	Oryzias_latipes
ENSMUSG00000020850	Prpf8	99	97.603	ENSORLG00020021070	prpf8	99	97.603	Oryzias_latipes_hni
ENSMUSG00000020850	Prpf8	99	97.645	ENSORLG00015002340	prpf8	99	97.645	Oryzias_latipes_hsok
ENSMUSG00000020850	Prpf8	99	96.144	ENSOMEG00000016866	prpf8	99	96.144	Oryzias_melastigma
ENSMUSG00000020850	Prpf8	100	99.786	ENSOARG00000013312	PRPF8	100	99.786	Ovis_aries
ENSMUSG00000020850	Prpf8	100	99.914	ENSPPAG00000042753	PRPF8	100	99.914	Pan_paniscus
ENSMUSG00000020850	Prpf8	100	99.914	ENSPPRG00000008746	PRPF8	100	99.914	Panthera_pardus
ENSMUSG00000020850	Prpf8	100	99.829	ENSPTIG00000019200	PRPF8	100	99.829	Panthera_tigris_altaica
ENSMUSG00000020850	Prpf8	100	99.914	ENSPTRG00000039576	PRPF8	100	99.914	Pan_troglodytes
ENSMUSG00000020850	Prpf8	99	98.971	ENSPANG00000024607	PRPF8	99	98.971	Papio_anubis
ENSMUSG00000020850	Prpf8	100	97.277	ENSPKIG00000011201	prpf8	100	97.277	Paramormyrops_kingsleyae
ENSMUSG00000020850	Prpf8	100	99.400	ENSPSIG00000013393	PRPF8	100	99.400	Pelodiscus_sinensis
ENSMUSG00000020850	Prpf8	100	99.957	ENSPEMG00000021699	Prpf8	100	99.957	Peromyscus_maniculatus_bairdii
ENSMUSG00000020850	Prpf8	96	93.898	ENSPMAG00000005438	prpf8	100	93.942	Petromyzon_marinus
ENSMUSG00000020850	Prpf8	100	99.743	ENSPCIG00000022603	PRPF8	100	99.777	Phascolarctos_cinereus
ENSMUSG00000020850	Prpf8	100	96.948	ENSPFOG00000007005	prpf8	100	96.948	Poecilia_formosa
ENSMUSG00000020850	Prpf8	100	96.360	ENSPLAG00000020777	prpf8	100	96.360	Poecilia_latipinna
ENSMUSG00000020850	Prpf8	100	96.948	ENSPMEG00000004051	prpf8	100	96.948	Poecilia_mexicana
ENSMUSG00000020850	Prpf8	100	97.602	ENSPREG00000021902	prpf8	100	97.602	Poecilia_reticulata
ENSMUSG00000020850	Prpf8	100	99.914	ENSPPYG00000007777	PRPF8	100	99.914	Pongo_abelii
ENSMUSG00000020850	Prpf8	90	99.647	ENSPCAG00000008938	PRPF8	90	99.647	Procavia_capensis
ENSMUSG00000020850	Prpf8	100	99.957	ENSPCOG00000015182	PRPF8	100	99.957	Propithecus_coquereli
ENSMUSG00000020850	Prpf8	93	100.000	ENSPVAG00000002134	PRPF8	93	100.000	Pteropus_vampyrus
ENSMUSG00000020850	Prpf8	100	97.561	ENSPNYG00000016356	prpf8	100	97.561	Pundamilia_nyererei
ENSMUSG00000020850	Prpf8	100	97.605	ENSPNAG00000009247	prpf8	100	97.605	Pygocentrus_nattereri
ENSMUSG00000020850	Prpf8	100	100.000	ENSRNOG00000003495	Prpf8	100	100.000	Rattus_norvegicus
ENSMUSG00000020850	Prpf8	100	99.914	ENSRBIG00000031219	PRPF8	100	99.914	Rhinopithecus_bieti
ENSMUSG00000020850	Prpf8	100	99.914	ENSRROG00000038014	PRPF8	100	99.914	Rhinopithecus_roxellana
ENSMUSG00000020850	Prpf8	99	62.430	YHR165C	PRP8	95	62.484	Saccharomyces_cerevisiae
ENSMUSG00000020850	Prpf8	100	99.914	ENSSBOG00000029717	PRPF8	100	99.914	Saimiri_boliviensis_boliviensis
ENSMUSG00000020850	Prpf8	100	99.700	ENSSHAG00000006167	PRPF8	100	99.700	Sarcophilus_harrisii
ENSMUSG00000020850	Prpf8	100	97.481	ENSSFOG00015013905	prpf8	100	97.481	Scleropages_formosus
ENSMUSG00000020850	Prpf8	100	97.352	ENSSMAG00000017736	prpf8	100	97.352	Scophthalmus_maximus
ENSMUSG00000020850	Prpf8	100	97.733	ENSSDUG00000003029	prpf8	100	97.733	Seriola_dumerili
ENSMUSG00000020850	Prpf8	68	98.874	ENSSLDG00000017096	prpf8	100	98.874	Seriola_lalandi_dorsalis
ENSMUSG00000020850	Prpf8	87	99.395	ENSSARG00000002892	PRPF8	87	99.395	Sorex_araneus
ENSMUSG00000020850	Prpf8	100	99.229	ENSSPUG00000007463	PRPF8	100	99.229	Sphenodon_punctatus
ENSMUSG00000020850	Prpf8	100	97.178	ENSSPAG00000015639	prpf8	100	97.178	Stegastes_partitus
ENSMUSG00000020850	Prpf8	100	99.914	ENSSSCG00000017817	PRPF8	100	99.914	Sus_scrofa
ENSMUSG00000020850	Prpf8	74	98.601	ENSTGUG00000015597	-	95	99.651	Taeniopygia_guttata
ENSMUSG00000020850	Prpf8	100	99.400	ENSTGUG00000005648	-	100	99.400	Taeniopygia_guttata
ENSMUSG00000020850	Prpf8	100	97.520	ENSTRUG00000015906	prpf8	100	97.520	Takifugu_rubripes
ENSMUSG00000020850	Prpf8	95	98.686	ENSTNIG00000003460	prpf8	99	98.686	Tetraodon_nigroviridis
ENSMUSG00000020850	Prpf8	93	99.932	ENSTBEG00000006431	PRPF8	93	99.932	Tupaia_belangeri
ENSMUSG00000020850	Prpf8	100	99.315	ENSTTRG00000006869	PRPF8	100	99.315	Tursiops_truncatus
ENSMUSG00000020850	Prpf8	100	94.904	ENSUAMG00000015644	-	96	99.921	Ursus_americanus
ENSMUSG00000020850	Prpf8	100	99.657	ENSUMAG00000009385	PRPF8	100	99.657	Ursus_maritimus
ENSMUSG00000020850	Prpf8	71	99.310	ENSVPAG00000006063	-	71	99.310	Vicugna_pacos
ENSMUSG00000020850	Prpf8	100	99.914	ENSVVUG00000021695	PRPF8	99	99.914	Vulpes_vulpes
ENSMUSG00000020850	Prpf8	100	98.801	ENSXETG00000022259	prpf8	100	98.801	Xenopus_tropicalis
ENSMUSG00000020850	Prpf8	100	97.523	ENSXCOG00000012775	prpf8	100	97.523	Xiphophorus_couchianus
ENSMUSG00000020850	Prpf8	100	97.481	ENSXMAG00000008505	prpf8	100	97.481	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000244	spliceosomal tri-snRNP complex assembly	21873635.	IBA	Process
GO:0000244	spliceosomal tri-snRNP complex assembly	-	ISO	Process
GO:0000386	second spliceosomal transesterification activity	21873635.	IBA	Function
GO:0000398	mRNA splicing, via spliceosome	-	ISO	Process
GO:0003723	RNA binding	-	IEA	Function
GO:0005634	nucleus	-	ISO	Component
GO:0005681	spliceosomal complex	-	IEA	Component
GO:0005682	U5 snRNP	21873635.	IBA	Component
GO:0005682	U5 snRNP	-	ISO	Component
GO:0006397	mRNA processing	-	IEA	Process
GO:0008380	RNA splicing	-	IEA	Process
GO:0017070	U6 snRNA binding	21873635.	IBA	Function
GO:0030532	small nuclear ribonucleoprotein complex	-	ISO	Component
GO:0030619	U1 snRNA binding	21873635.	IBA	Function
GO:0030620	U2 snRNA binding	21873635.	IBA	Function
GO:0030623	U5 snRNA binding	21873635.	IBA	Function
GO:0046540	U4/U6 x U5 tri-snRNP complex	-	ISO	Component
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	-	ISO	Function
GO:0071005	U2-type precatalytic spliceosome	-	ISO	Component
GO:0071007	U2-type catalytic step 2 spliceosome	-	ISO	Component
GO:0071013	catalytic step 2 spliceosome	21873635.	IBA	Component
GO:0071013	catalytic step 2 spliceosome	-	ISO	Component
GO:0071222	cellular response to lipopolysaccharide	-	ISO	Process
GO:0071356	cellular response to tumor necrosis factor	-	ISO	Process
GO:0097157	pre-mRNA intronic binding	21873635.	IBA	Function