EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
CESC	chr6	36704311	Missense_Mutation	novel	A26T	0.32
CESC	chr6	36730698	Missense_Mutation	novel	C874Y	0.34
CESC	chr6	36715584	Missense_Mutation	rs747648674	A41V	0.23
UCEC	chr6	36704420	Missense_Mutation	novel	F62C	0.11
UCEC	chr6	36713878	5'Flank	novel		0.14
UCEC	chr6	36732158	3'UTR	novel		0.07
UCEC	chr6	36704365	Missense_Mutation	novel	A44T	0.34
UCEC	chr6	36732229	3'UTR	novel		0.42
UCEC	chr6	36732072	Missense_Mutation	novel	K914N	0.44
UCEC	chr6	36713921	5'Flank	novel		0.41
UCEC	chr6	36704294	Missense_Mutation	novel	R20L	0.39
UCEC	chr6	36732101	3'UTR	novel		0.32
UCEC	chr6	36730706	Missense_Mutation	novel	A877T	0.27

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value

Survival Analysis

Cancer	P-value	Q-value
STAD	0.035	Kaplan-Meier Survival Analysis
SARC	0.00012	Kaplan-Meier Survival Analysis
MESO	0.033	Kaplan-Meier Survival Analysis
ACC	0.011	Kaplan-Meier Survival Analysis
HNSC	0.0003	Kaplan-Meier Survival Analysis
PCPG	0.032	Kaplan-Meier Survival Analysis
LAML	0.0058	Kaplan-Meier Survival Analysis
LIHC	0.034	Kaplan-Meier Survival Analysis
DLBC	0.022	Kaplan-Meier Survival Analysis
LGG	0.044	Kaplan-Meier Survival Analysis
LUAD	0.0001	Kaplan-Meier Survival Analysis

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000255587 (Gene tree)
Gene ID: 401258
Gene Symbol: RAB44
Alias: dJ431A14.3|RASD3|RASL13
Full Name: RAB44, member RAS oncogene family
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 35,374 bases
Position: chr6:36,697,810-36,733,183
Accession: 21068
RBP type: canonical RBP
Summary: RAB44 (RAB44, Member RAS Oncogene Family) is a Protein Coding gene. Among its related pathways are RAB geranylgeranylation and Innate Immune System. Gene Ontology (GO) annotations related to this gene include calcium ion binding and GTPase activity. An important paralog of this gene is RASEF.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000481054	MMR_HSR1	PF01926.23	2.3e-05	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000612677	RAB44-201	4274	XM_024446435	ENSP00000481054	1021 (aa)	XP_024302203	Q7Z6P3

Gene Model

Click here to download ENSG00000255587's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000255587	Pancreatic Neoplasms	9.3860000E-005	19648918
ENSG00000255587	Pancreatic Neoplasms	9.4020000E-005	19648918
ENSG00000255587	Pancreatic Neoplasms	1.6390000E-004	19648918

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000255587's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000255587	RAB44	75	62.532	ENSAMEG00000000257	-	100	62.532	Ailuropoda_melanoleuca
ENSG00000255587	RAB44	100	87.757	ENSANAG00000027844	RAB44	100	87.855	Aotus_nancymaae
ENSG00000255587	RAB44	99	66.118	ENSBTAG00000050445	RAB44	99	65.544	Bos_taurus
ENSG00000255587	RAB44	100	86.680	ENSCJAG00000016070	RAB44	100	86.778	Callithrix_jacchus
ENSG00000255587	RAB44	76	62.436	ENSCAFG00000001418	-	99	62.051	Canis_familiaris
ENSG00000255587	RAB44	99	66.375	ENSCAFG00020007300	RAB44	99	66.084	Canis_lupus_dingo
ENSG00000255587	RAB44	52	72.659	ENSCHIG00000015827	RAB44	100	68.519	Capra_hircus
ENSG00000255587	RAB44	100	71.512	ENSTSYG00000037416	RAB44	100	71.512	Carlito_syrichta
ENSG00000255587	RAB44	76	53.017	ENSCAPG00000017850	-	100	52.618	Cavia_aperea
ENSG00000255587	RAB44	99	57.941	ENSCPOG00000035721	RAB44	99	57.647	Cavia_porcellus
ENSG00000255587	RAB44	100	83.855	ENSCCAG00000028656	RAB44	100	83.953	Cebus_capucinus
ENSG00000255587	RAB44	100	89.622	ENSCATG00000039932	RAB44	100	89.622	Cercocebus_atys
ENSG00000255587	RAB44	100	61.300	ENSCLAG00000010513	RAB44	100	61.106	Chinchilla_lanigera
ENSG00000255587	RAB44	50	65.104	ENSCPBG00000025279	RAB44	54	65.104	Chrysemys_picta_bellii
ENSG00000255587	RAB44	100	91.969	ENSCANG00000035408	RAB44	100	91.969	Colobus_angolensis_palliatus
ENSG00000255587	RAB44	76	56.138	ENSCGRG00001019434	Rab44	99	54.987	Cricetulus_griseus_chok1gshd
ENSG00000255587	RAB44	76	56.010	ENSCGRG00000015338	Rab44	99	54.987	Cricetulus_griseus_crigri
ENSG00000255587	RAB44	99	70.760	ENSEASG00005021342	RAB44	99	71.345	Equus_asinus_asinus
ENSG00000255587	RAB44	99	70.554	ENSECAG00000000519	RAB44	99	71.137	Equus_caballus
ENSG00000255587	RAB44	99	68.787	ENSFCAG00000023379	RAB44	99	68.787	Felis_catus
ENSG00000255587	RAB44	52	59.624	ENSGAGG00000024451	RAB44	56	59.624	Gopherus_agassizii
ENSG00000255587	RAB44	100	98.629	ENSGGOG00000005759	RAB44	100	98.629	Gorilla_gorilla
ENSG00000255587	RAB44	75	57.458	ENSHGLG00000017024	-	100	57.458	Heterocephalus_glaber_female
ENSG00000255587	RAB44	75	57.383	ENSHGLG00100013111	-	100	57.383	Heterocephalus_glaber_male
ENSG00000255587	RAB44	75	66.154	ENSSTOG00000020682	-	99	66.797	Ictidomys_tridecemlineatus
ENSG00000255587	RAB44	76	55.216	ENSJJAG00000021852	Rab44	100	55.216	Jaculus_jaculus
ENSG00000255587	RAB44	100	92.067	ENSMFAG00000000117	RAB44	100	92.067	Macaca_fascicularis
ENSG00000255587	RAB44	100	91.969	ENSMMUG00000003214	RAB44	100	91.969	Macaca_mulatta
ENSG00000255587	RAB44	97	92.698	ENSMNEG00000007050	RAB44	99	92.698	Macaca_nemestrina
ENSG00000255587	RAB44	100	92.165	ENSMLEG00000034248	RAB44	100	92.165	Mandrillus_leucophaeus
ENSG00000255587	RAB44	76	55.711	ENSMAUG00000006085	Rab44	99	55.032	Mesocricetus_auratus
ENSG00000255587	RAB44	76	57.070	ENSMOCG00000015106	Rab44	99	57.070	Microtus_ochrogaster
ENSG00000255587	RAB44	62	70.984	ENSMODG00000013525	-	65	70.984	Monodelphis_domestica
ENSG00000255587	RAB44	76	55.203	MGP_CAROLIEiJ_G0021338	Rab44	99	54.974	Mus_caroli
ENSG00000255587	RAB44	99	60.077	ENSMUSG00000064147	Rab44	98	79.070	Mus_musculus
ENSG00000255587	RAB44	76	55.457	MGP_SPRETEiJ_G0022251	Rab44	99	54.974	Mus_spretus
ENSG00000255587	RAB44	76	59.536	ENSNGAG00000014378	Rab44	100	59.536	Nannospalax_galili
ENSG00000255587	RAB44	93	90.938	ENSNLEG00000010749	RAB44	100	90.938	Nomascus_leucogenys
ENSG00000255587	RAB44	76	64.602	ENSOGAG00000026730	-	99	64.602	Otolemur_garnettii
ENSG00000255587	RAB44	100	98.923	ENSPPAG00000043639	RAB44	100	98.923	Pan_paniscus
ENSG00000255587	RAB44	99	69.178	ENSPPRG00000011437	RAB44	99	69.178	Panthera_pardus
ENSG00000255587	RAB44	99	68.585	ENSPTIG00000017870	RAB44	99	68.585	Panthera_tigris_altaica
ENSG00000255587	RAB44	100	99.021	ENSPTRG00000045813	RAB44	100	99.021	Pan_troglodytes
ENSG00000255587	RAB44	100	91.969	ENSPANG00000006938	RAB44	100	91.969	Papio_anubis
ENSG00000255587	RAB44	76	56.760	ENSPEMG00000008688	Rab44	99	56.760	Peromyscus_maniculatus_bairdii
ENSG00000255587	RAB44	100	72.904	ENSPCOG00000027072	RAB44	100	72.904	Propithecus_coquereli
ENSG00000255587	RAB44	76	53.503	ENSRNOG00000001869	Rab44	99	53.631	Rattus_norvegicus
ENSG00000255587	RAB44	100	91.871	ENSRBIG00000018383	RAB44	100	91.871	Rhinopithecus_bieti
ENSG00000255587	RAB44	100	91.969	ENSRROG00000037377	RAB44	100	91.969	Rhinopithecus_roxellana
ENSG00000255587	RAB44	99	68.707	ENSSSCG00000001566	RAB44	99	68.610	Sus_scrofa
ENSG00000255587	RAB44	93	65.765	ENSUAMG00000000136	RAB44	95	66.077	Ursus_americanus
ENSG00000255587	RAB44	99	58.140	ENSUMAG00000009974	RAB44	99	70.958	Ursus_maritimus
ENSG00000255587	RAB44	99	66.181	ENSVVUG00000026366	RAB44	99	65.889	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003924	GTPase activity	21873635.	IBA	Function
GO:0005509	calcium ion binding	-	IEA	Function
GO:0005525	GTP binding	-	IEA	Function
GO:0005886	plasma membrane	-	TAS	Component
GO:0006886	intracellular protein transport	21873635.	IBA	Process
GO:0032482	Rab protein signal transduction	21873635.	IBA	Process
GO:0035577	azurophil granule membrane	-	TAS	Component
GO:0035579	specific granule membrane	-	TAS	Component
GO:0043312	neutrophil degranulation	-	TAS	Process

Note: Click here to get the extension of tumor abbreviations.

Note: to get the extension of tumor abbreviations.