EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
27344963	DDX3 Represses Stemness by Epigenetically Modulating Tumor-suppressive miRNAs in Hepatocellular Carcinoma.	Sci Rep	2016 Jun 27	Li HK	doi: 10.1038/srep28637.
27007150	DDX3 enhances oncogenic KRASinduced tumor invasion in colorectal cancer via the βcatenin/ZEB1 axis.	Oncotarget	2016 Apr 19	Wu DW	doi: 10.18632/oncotarget.8143.
16818630	DDX3, a DEAD box RNA helicase with tumor growth-suppressive property and transcriptional regulation activity of the p21waf1/cip1 promoter, is a candidate tumor suppressor.	Cancer Res	2006 Jul 1	Chao CH	-
23410059	Low/negative expression of DDX3 might predict poor prognosis in non-smoker patients with oral cancer.	Oral Dis	2014 Jan	Lee CH	doi: 10.1111/odi.12076
23584477	DDX3 loss by p53 inactivation promotes tumor malignancy via the MDM2/Slug/E-cadherin pathway and poor patient outcome in non-small-cell lung cancer.	Oncogene	2014 Mar 20	Wu DW	doi: 10.1038/onc.2013.107
23330003	Nectin-2 and DDX3 are biomarkers for metastasis and poor prognosis of squamous cell/adenosquamous carcinomas and adenocarcinoma of gallbladder.	Int J Clin Exp Pathol	2013	Miao X	-
26087195	DDX3 as a strongest prognosis marker and its downregulation promotes metastasis in colorectal cancer.	Oncotarget	2015 Jul 30	Su CY	-
25918862	Ketorolac salt is a newly discovered DDX3 inhibitor to treat oral cancer.	Sci Rep	2015 Apr 28	Samal SK	doi: 10.1038/srep09982.
25724843	Cancer-associated mutants of RNA helicase DDX3X are defective in RNA-stimulated ATP hydrolysis.	J Mol Biol	2015 May 8	Epling LB	doi: 10.1016/j.jmb.2015.02.015
25343452	DDX3X induces primary EGFR-TKI resistance based on intratumor heterogeneity in lung cancer cells harboring EGFR-activating mutations.	PLoS One	2014 Oct 24	Nozaki K	doi: 10.1371/journal.pone.0111019
26337079	NZ51, a ring-expanded nucleoside analog, inhibits motility and viability of breast cancer cells by targeting the RNA helicase DDX3.	Oncotarget	2015 Oct 6	Xie M	doi: 10.18632/oncotarget.4898.
27999982	The prognostic effect of DDX3 upregulation in distant breast cancer metastases.	Clin Exp Metastasis	2017 Jan	Heerma van Voss MR	doi: 10.1007/s10585-016-9832-8
29203243	Rottlerin upregulates DDX3 expression in hepatocellular carcinoma.	Biochem Biophys Res Commun	2018 Jan 1	Wang Z	doi: 10.1016/j.bbrc.2017.11.198
27058758	Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress.	Oncotarget	2016 May 10	Oh S	doi: 10.18632/oncotarget.8612.
27180681	Cancer-associated DDX3X mutations drive stress granule assembly and impair global translation.	Sci Rep	2016 May 16	Valentin-Vega YA	doi: 10.1038/srep25996.

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chrX	41337425	Silent	novel	L21L	0.09
BLCA	chrX	41342587	Missense_Mutation	novel	R126P	0.18
BLCA	chrX	41343819	Missense_Mutation	NA	M254I	0.5	DEAD
BLCA	chrX	41347437	Missense_Mutation	novel	R632K	0.31
BLCA	chrX	41347378	Frame_Shift_Ins	novel	*S614Qfs17**	0.75
BLCA	chrX	41345449	Nonsense_Mutation	NA	G406*	0.08
BLCA	chrX	41346537	Silent	novel	V510V	0.06
BLCA	chrX	41346563	In_Frame_Del	novel	P519_S520delinsR	0.11
BLCA	chrX	41345215	Missense_Mutation	NA	D354V	0.15	DEAD
BLCA	chrX	41343780	Silent	NA	Q241Q	0.24
BLCA	chrX	41344359	Missense_Mutation	novel	D329H	0.43	DEAD
BLCA	chrX	41341570	Frame_Shift_Del	novel	*G80Efs3**	0.13
BLCA	chrX	41337430	Missense_Mutation	novel	S23F	0.17
BLCA	chrX	41345242	Missense_Mutation	novel	R363K	0.11
BLCA	chrX	41345403	Splice_Site	novel	X391_splice	0.31
BLCA	chrX	41347676	Missense_Mutation	novel	G649E	0.23
BLCA	chrX	41347337	Missense_Mutation	novel	A599S	0.76
BLCA	chrX	41347013	Splice_Site	novel	X590_splice	0.43
BRCA	chrX	41342635	Missense_Mutation	NA	P142L	0.17
BRCA	chrX	41333554	5'UTR	novel		0.17
BRCA	chrX	41346234	Missense_Mutation	NA	D441H	0.21
BRCA	chrX	41345484	Silent	NA	Q417Q	0.12
BRCA	chrX	41347449	Missense_Mutation	novel	G636E	0.23
BRCA	chrX	41341535	Missense_Mutation	NA	A68V	0.1
BRCA	chrX	41337443	Missense_Mutation	NA	Q27H	0.42
BRCA	chrX	41334210	5'UTR	novel		0.12
BRCA	chrX	41342776	Silent	NA	E161E	0.34
BRCA	chrX	41347415	Missense_Mutation	novel	G625R	0.06
BRCA	chrX	41346918	Missense_Mutation	NA	L559I	0.21
BRCA	chrX	41344252	Missense_Mutation	NA	S293Y	0.16	DEAD
CESC	chrX	41346515	Missense_Mutation	novel	R503T	0.09
CESC	chrX	41346602	Missense_Mutation	NA	T532M	0.42
CESC	chrX	41343819	Missense_Mutation	NA	M254I	0.43	DEAD
CESC	chrX	41342755	Frame_Shift_Ins	novel	*Y163Hfs4**	0.27
CESC	chrX	41346530	Missense_Mutation	NA	S508L	0.36
CESC	chrX	41343288	Missense_Mutation	NA	V206L	0.21	DEAD
CESC	chrX	41343249	Missense_Mutation	novel	G193R	0.41
CESC	chrX	41344052	Missense_Mutation	NA	R263H	0.44	DEAD
CESC	chrX	41347847	3'UTR	novel		0.37
CESC	chrX	41348591	3'UTR	novel		0.5
CESC	chrX	41342584	Frame_Shift_Ins	novel	*R126Lfs96**	0.62
CESC	chrX	41342602	Nonsense_Mutation	novel	S131*	0.34
CESC	chrX	41344351	Missense_Mutation	rs797045025	R326H	0.09	DEAD
CESC	chrX	41347349	Nonsense_Mutation	novel	R603*	0.32
CESC	chrX	41346605	Missense_Mutation	novel	G533E	0.35
CESC	chrX	41345425	Missense_Mutation	NA	D398H	0.2
CESC	chrX	41342649	Nonsense_Mutation	novel	E147*	0.06
CESC	chrX	41334255	Translation_Start_Site	novel	M1?	0.2
CHOL	chrX	41334179	5'UTR	novel		0.94
COAD	chrX	41342522	Silent	rs750187385	Y104Y	0.59
COAD	chrX	41346908	Missense_Mutation	NA	D555E	0.6
COAD	chrX	41346547	Missense_Mutation	NA	I514V	0.44
COAD	chrX	41345503	Nonsense_Mutation	NA	E424*	0.21
COAD	chrX	41346393	Missense_Mutation	novel	I494L	0.05
COAD	chrX	41347847	3'UTR	novel		0.4
COAD	chrX	41342572	Missense_Mutation	NA	R121H	0.52
COAD	chrX	41343296	Missense_Mutation	novel	K208N	0.04	DEAD
COAD	chrX	41334189	5'UTR	NA		0.14
COAD	chrX	41347847	3'UTR	novel		0.35
COAD	chrX	41347847	3'UTR	novel		0.41
COAD	chrX	41347847	3'UTR	novel		0.31
COAD	chrX	41347847	3'UTR	novel		0.71
COAD	chrX	41342547	Missense_Mutation	novel	R113G	0.42
COAD	chrX	41347648	Missense_Mutation	novel	G640R	0.03
COAD	chrX	41347649	Frame_Shift_Ins	novel	*G641Afs32**	0.03
DLBC	chrX	41347350	Missense_Mutation	novel	R603Q	0.65
DLBC	chrX	41345549	Splice_Site	novel	X439_splice	0.53
DLBC	chrX	41344299	Nonsense_Mutation	NA	Q309*	0.06	DEAD
ESCA	chrX	41342782	Silent	rs769546741	Y163Y	0.25
ESCA	chrX	41347702	Missense_Mutation	novel	D658H	0.29
ESCA	chrX	41348893	3'UTR	novel		0.19
ESCA	chrX	41342522	Silent	rs750187385	Y104Y	0.77
GBM	chrX	41347429	In_Frame_Ins	novel	S631dup	0.65
GBM	chrX	41337460	Missense_Mutation	novel	A33G	0.11
HNSC	chrX	41334255	Translation_Start_Site	novel	M1?	0.81
HNSC	chrX	41346352	Missense_Mutation	novel	R480T	0.41
HNSC	chrX	41346568	Missense_Mutation	novel	D521H	0.36
HNSC	chrX	41342556	Frame_Shift_Del	novel	*F116Lfs105**	0.42
HNSC	chrX	41344372	Missense_Mutation	novel	R333T	0.56	DEAD
HNSC	chrX	41347426	Silent	rs779341057	H628H	0.19
HNSC	chrX	41346589	Missense_Mutation	NA	R528C	0.66
HNSC	chrX	41345470	Frame_Shift_Ins	novel	*N414Kfs20**	0.16
HNSC	chrX	41337465	Frame_Shift_Ins	novel		0.48
KIRC	chrX	41342831	Missense_Mutation	NA	E180Q	0.15
KIRC	chrX	41344243	Missense_Mutation	NA	S290L	0.31	DEAD
KIRC	chrX	41344290	Frame_Shift_Ins	novel	*G307Wfs42**	0.62	DEAD
KIRP	chrX	41342751	Missense_Mutation	NA	G153E	0.38
KIRP	chrX	41343776	Missense_Mutation	novel	S240I	0.11	DEAD
LAML	chrX	41344350	Missense_Mutation	NA	R326C	0.05	DEAD
LGG	chrX	41345205	Missense_Mutation	NA	R351W	0.5	DEAD
LUAD	chrX	41342559	Frame_Shift_Del	novel	*G117Afs104**	0.32
LUAD	chrX	41347394	Missense_Mutation	rs756197314	A618T	0.2
LUAD	chrX	41344088	Missense_Mutation	NA	T275M	0.33	DEAD
LUAD	chrX	41346986	Frame_Shift_Del	novel	*G582Vfs87**	0.29
LUAD	chrX	41345494	Frame_Shift_Del	novel	*V422Kfs13**	0.5
LUAD	chrX	41344358	Silent	novel	V328V	0.42
LUAD	chrX	41347829	3'UTR	novel		0.22
LUAD	chrX	41347831	3'UTR	novel		0.22
LUAD	chrX	41345442	Missense_Mutation	novel	L403F	0.1
LUSC	chrX	41345410	Missense_Mutation	NA	A393T	0.51
LUSC	chrX	41342604	Missense_Mutation	NA	D132N	0.49
LUSC	chrX	41344063	Missense_Mutation	novel	P267T	0.26	DEAD
LUSC	chrX	41344029	Splice_Site	novel	X256_splice	1
LUSC	chrX	41347350	Missense_Mutation	novel	R603Q	0.45
LUSC	chrX	41346550	Nonsense_Mutation	novel	*N515Tfs2**	0.11
LUSC	chrX	41345513	Missense_Mutation	novel	K427T	0.43
LUSC	chrX	41339068	Nonsense_Mutation	novel	R46*	0.6
LUSC	chrX	41347639	Splice_Site	novel	X637_splice	0.35
LUSC	chrX	41347694	Frame_Shift_Ins	novel	*V657Gfs2**	0.73
LUSC	chrX	41334255	Translation_Start_Site	novel	M1?	0.6
LUSC	chrX	41339023	Splice_Site	novel	X35_splice	0.82
LUSC	chrX	41345214	Missense_Mutation	NA	D354Y	0.79	DEAD
MESO	chrX	41342782	Frame_Shift_Del	novel	Y163*	0.67
OV	chrX	41346886	Missense_Mutation	NA	R548T	0.49
OV	chrX	41346894	Missense_Mutation	NA	N551H	0.53
OV	chrX	41346997	Missense_Mutation	novel	R585L	0.06
OV	chrX	41347651	Missense_Mutation	novel	G641C	0.08
OV	chrX	41345408	Missense_Mutation	novel	L392Q	0.07
PAAD	chrX	41345259	Missense_Mutation	novel	T369A	0.25
PRAD	chrX	41346313	Missense_Mutation	novel	A467V	0.32
READ	chrX	41347847	3'UTR	novel		0.46
SARC	chrX	41346909	Missense_Mutation	novel	L556M	0.69
SARC	chrX	41346910	Nonsense_Mutation	novel	L556*	0.68
SKCM	chrX	41344243	Missense_Mutation	NA	S290L	0.56	DEAD
SKCM	chrX	41339080	Nonsense_Mutation	novel	K50*	0.98
SKCM	chrX	41341494	Frame_Shift_Ins	novel	*D56Rfs8**	0.9
SKCM	chrX	41346252	Missense_Mutation	NA	F447L	0.21
SKCM	chrX	41346342	Nonsense_Mutation	novel	Q477*	0.9
SKCM	chrX	41345495	Nonsense_Mutation	novel	W421*	0.98
SKCM	chrX	41344264	Frame_Shift_Del	novel	*P297Rfs22**	0.21	DEAD
SKCM	chrX	41346918	Missense_Mutation	NA	L559F	0.85
SKCM	chrX	41346563	Missense_Mutation	novel	P519L	0.26
SKCM	chrX	41344305	Nonsense_Mutation	NA	R311*	0.87	DEAD
SKCM	chrX	41344117	Missense_Mutation	NA	E285K	0.7	DEAD
SKCM	chrX	41345468	Missense_Mutation	NA	S412F	0.79
SKCM	chrX	41337433	Nonsense_Mutation	NA	S24*	0.33
SKCM	chrX	41345301	Missense_Mutation	NA	A383T	0.18
SKCM	chrX	41347694	Frame_Shift_Ins	novel	*V657Gfs2**	0.51
SKCM	chrX	41343271	Missense_Mutation	NA	Y200S	0.47
SKCM	chrX	41345468	Missense_Mutation	NA	S412F	0.85
SKCM	chrX	41339068	Nonsense_Mutation	novel	R46*	0.32
SKCM	chrX	41346336	Missense_Mutation	NA	R475C	0.31
SKCM	chrX	41346601	Missense_Mutation	NA	T532A	0.82
SKCM	chrX	41343302	Silent	NA	A210A	0.27
SKCM	chrX	41344116	Silent	novel	E284E	0.93
SKCM	chrX	41344117	Missense_Mutation	NA	E285K	0.93	DEAD
SKCM	chrX	41343209	Splice_Site	novel	X182_splice	0.4
SKCM	chrX	41344117	Missense_Mutation	NA	E285K	0.94	DEAD
SKCM	chrX	41341534	Frame_Shift_Del	novel	*A68Rfs153**	0.89
SKCM	chrX	41347702	Missense_Mutation	NA	D658Y	0.36
SKCM	chrX	41346592	Missense_Mutation	NA	I529L	0.63
STAD	chrX	41344046	Missense_Mutation	novel	G261V	0.19	DEAD
STAD	chrX	41346397	Splice_Site	novel	X495_splice	0.47
STAD	chrX	41346379	Nonsense_Mutation	novel	S489*	0.77
STAD	chrX	41345214	Missense_Mutation	NA	D354Y	0.56	DEAD
STAD	chrX	41342505	Missense_Mutation	NA	R99C	0.33
STAD	chrX	41337453	Missense_Mutation	novel	S31R	0.23
STAD	chrX	41347002	Missense_Mutation	novel	R587C	0.79
STAD	chrX	41346522	Silent	NA	L505L	0.12
STAD	chrX	41342511	Missense_Mutation	novel	R101W	0.25
STAD	chrX	41344299	Nonsense_Mutation	NA	Q309*	0.37	DEAD
STAD	chrX	41346264	Frame_Shift_Del	NA	*K452Rfs44**	0.26
STAD	chrX	41346589	Missense_Mutation	NA	R528C	0.09
STAD	chrX	41343267	Missense_Mutation	NA	R199C	0.24
STAD	chrX	41342538	Missense_Mutation	NA	R110C	0.25
STAD	chrX	41343801	Silent	NA	G248G	0.11
STAD	chrX	41344049	Missense_Mutation	NA	R262H	0.1	DEAD
STAD	chrX	41342506	Missense_Mutation	NA	R99H	0.06
STAD	chrX	41346607	Missense_Mutation	NA	R534C	0.23
STAD	chrX	41343801	Silent	NA	G248G	0.12
TGCT	chrX	41345547	Frame_Shift_Ins	novel		0.15
TGCT	chrX	41346337	Missense_Mutation	novel	R475P	0.07
THYM	chrX	41348924	3'UTR	novel		0.38
UCEC	chrX	41343268	Missense_Mutation	NA	R199P	0.33
UCEC	chrX	41342533	Missense_Mutation	NA	G108D	0.29
UCEC	chrX	41348206	3'UTR	novel		0.21
UCEC	chrX	41344052	Missense_Mutation	NA	R263H	0.39	DEAD
UCEC	chrX	41348015	3'UTR	novel		0.07
UCEC	chrX	41348843	3'UTR	novel		0.46
UCEC	chrX	41350190	3'UTR	novel		0.35
UCEC	chrX	41348832	3'UTR	novel		0.35
UCEC	chrX	41349037	3'UTR	novel		0.3
UCEC	chrX	41342538	Missense_Mutation	NA	R110C	0.38
UCEC	chrX	41346602	Missense_Mutation	NA	T532M	0.21
UCEC	chrX	41342542	Missense_Mutation	novel	G111D	0.05
UCEC	chrX	41339077	Missense_Mutation	novel	T49A	0.3
UCEC	chrX	41350271	3'UTR	novel		0.51
UCEC	chrX	41344305	Nonsense_Mutation	NA	R311*	0.37	DEAD
UCEC	chrX	41348576	3'UTR	novel		0.35
UCEC	chrX	41333744	5'UTR	novel		0.42
UCEC	chrX	41346608	Missense_Mutation	NA	R534H	0.46
UCEC	chrX	41347762	3'UTR	novel		0.48
UCEC	chrX	41349143	3'UTR	novel		0.31
UCEC	chrX	41348431	3'UTR	novel		0.25
UCEC	chrX	41345430	Missense_Mutation	NA	E399D	0.25
UCEC	chrX	41346526	Missense_Mutation	NA	I507V	0.06
UCEC	chrX	41342523	Missense_Mutation	novel	D105N	0.05
UCEC	chrX	41347812	3'UTR	novel		0.3
UCEC	chrX	41342819	Missense_Mutation	novel	P176S	0.19
UCEC	chrX	41341483	Splice_Site	NA	X51_splice	0.38
UCEC	chrX	41346589	Missense_Mutation	NA	R528C	0.46
UCEC	chrX	41347349	Frame_Shift_Del	NA	*Q604Cfs23**	0.29
UCEC	chrX	41347437	Missense_Mutation	NA	R632I	0.37
UCEC	chrX	41347847	3'UTR	novel		0.5
UCEC	chrX	41345450	Missense_Mutation	novel	G406V	0.13
UCEC	chrX	41342764	Silent	novel	G157G	0.11
UCEC	chrX	41348087	3'UTR	novel		0.09
UCEC	chrX	41350126	3'UTR	novel		0.32
UCEC	chrX	41343252	Missense_Mutation	novel	N194H	0.34
UCEC	chrX	41344089	Silent	novel	T275T	0.33
UCEC	chrX	41350260	3'UTR	novel		0.36
UCEC	chrX	41345311	Missense_Mutation	novel	P386R	0.46
UCEC	chrX	41345548	Missense_Mutation	novel	G439C	0.56
UCEC	chrX	41347414	Silent	rs757518275	G624G	0.41
UCEC	chrX	41349308	3'UTR	novel		0.28
UCEC	chrX	41347847	3'UTR	novel		0.35
UCEC	chrX	41349728	3'UTR	novel		0.08
UCEC	chrX	41348144	3'UTR	novel		0.53
UCEC	chrX	41334174	5'UTR	novel		0.46
UCEC	chrX	41345238	Missense_Mutation	rs797045026	R362C	0.52
UCEC	chrX	41349308	3'UTR	novel		0.34
UCEC	chrX	41343237	Nonsense_Mutation	novel	E189*	0.35
UCEC	chrX	41343327	Missense_Mutation	NA	D219Y	0.48	DEAD
UCEC	chrX	41346590	Missense_Mutation	NA	R528H	0.32
UCEC	chrX	41348799	3'UTR	novel		0.32
UCEC	chrX	41345306	Frame_Shift_Del	novel	*P386Lfs12**	0.37
UCEC	chrX	41339041	Missense_Mutation	novel	R37S	0.52
UCEC	chrX	41348178	3'UTR	novel		0.41
UCEC	chrX	41349283	3'UTR	novel		0.38
UCEC	chrX	41346946	Missense_Mutation	NA	P568L	0.41
UCEC	chrX	41344073	Nonsense_Mutation	novel	L270*	0.35	DEAD
UCEC	chrX	41342537	Silent	NA	S109S	0.41
UCEC	chrX	41341570	Missense_Mutation	novel	G80R	0.31
UCEC	chrX	41349025	3'UTR	novel		0.31
UCEC	chrX	41349475	3'UTR	novel		0.4
UCEC	chrX	41343308	Silent	novel	P212P	0.09
UCEC	chrX	41350220	3'UTR	novel		0.4
UCEC	chrX	41334236	5'UTR	novel		0.29
UCEC	chrX	41347847	3'UTR	novel		0.2
UCEC	chrX	41346946	Missense_Mutation	NA	P568L	0.44
UCEC	chrX	41345203	Missense_Mutation	novel	D350A	0.1	DEAD
UCEC	chrX	41347817	3'UTR	novel		0.09
UCEC	chrX	41348277	3'UTR	novel		0.3
UCEC	chrX	41348790	3'UTR	novel		0.26
UCEC	chrX	41344318	Missense_Mutation	novel	R315H	0.43	DEAD
UCEC	chrX	41348216	3'UTR	novel		0.5
UCEC	chrX	41348933	3'UTR	novel		0.45
UCEC	chrX	41349657	3'UTR	novel		0.41
UCEC	chrX	41349378	3'UTR	novel		0.11
UCEC	chrX	41343802	Missense_Mutation	rs752738546	E249K	0.38	DEAD
UCEC	chrX	41347847	3'UTR	novel		0.52
UCEC	chrX	41349074	3'UTR	novel		0.3
UCEC	chrX	41349624	3'UTR	novel		0.26
UCEC	chrX	41347350	Missense_Mutation	novel	R603Q	0.31
UCEC	chrX	41348357	3'UTR	novel		0.43
UCEC	chrX	41347847	3'UTR	novel		0.51
UCEC	chrX	41334112	5'UTR	novel		0.38
UCEC	chrX	41345223	Missense_Mutation	NA	F357L	0.05	DEAD
UCEC	chrX	41347847	3'UTR	novel		0.93
UCEC	chrX	41347847	3'UTR	novel		0.42
UCEC	chrX	41348117	3'UTR	novel		0.26
UCEC	chrX	41349312	3'UTR	novel		0.13
UCEC	chrX	41347847	3'UTR	novel		0.38
UCEC	chrX	41345196	Missense_Mutation	NA	E348K	0.11	DEAD
UCEC	chrX	41346390	Missense_Mutation	novel	P493S	0.45
UCEC	chrX	41347365	Frame_Shift_Ins	novel	*S609Qfs22**	0.04
UCEC	chrX	41347366	Nonsense_Mutation	novel	S609*	0.04
UCEC	chrX	41344051	Missense_Mutation	novel	R263C	0.42	DEAD
UCEC	chrX	41345315	Missense_Mutation	novel	K387N	0.08
UCEC	chrX	41347847	3'UTR	novel		0.21
UCEC	chrX	41347847	3'UTR	novel		0.47
UCEC	chrX	41348711	3'UTR	novel		0.33
UCEC	chrX	41350176	3'UTR	novel		0.45
UCEC	chrX	41346264	Frame_Shift_Del	NA	*K452Rfs44**	0.35
UCEC	chrX	41346622	Missense_Mutation	novel	G539R	0.49
UCEC	chrX	41347847	3'UTR	novel		0.6
UCEC	chrX	41341504	Missense_Mutation	novel	S58T	0.29
UCEC	chrX	41343296	Missense_Mutation	NA	K208N	0.5	DEAD
UCEC	chrX	41345238	Missense_Mutation	rs797045026	R362C	0.44
UCEC	chrX	41347847	3'UTR	novel		0.62
UCEC	chrX	41346590	Missense_Mutation	NA	R528H	0.33
UCEC	chrX	41346589	Missense_Mutation	NA	R528C	0.36
UCEC	chrX	41346238	Nonsense_Mutation	novel	S442*	0.09
UCEC	chrX	41339041	Missense_Mutation	NA	R37C	0.38
UCEC	chrX	41347704	Missense_Mutation	novel	D658E	0.39
UCEC	chrX	41334090	5'UTR	novel		0.5
UCEC	chrX	41347847	3'UTR	novel		0.36
UCEC	chrX	41349773	3'UTR	novel		0.41
UCEC	chrX	41344052	Missense_Mutation	NA	R263H	0.27	DEAD
UCEC	chrX	41346881	Silent	NA	N546N	0.24
UCEC	chrX	41347847	3'UTR	novel		0.67
UCEC	chrX	41343807	Silent	novel	A250A	0.18

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
SARC	AMP	0.2996	0.19108
THCA	DEL	0.002	0.21991

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00063	Kaplan-Meier Survival Analysis
SKCM	0.015	Kaplan-Meier Survival Analysis
BRCA	0.0061	Kaplan-Meier Survival Analysis
ESCA	0.015	Kaplan-Meier Survival Analysis
COAD	0.048	Kaplan-Meier Survival Analysis
PAAD	0.041	Kaplan-Meier Survival Analysis
LAML	0.0049	Kaplan-Meier Survival Analysis
LIHC	0.0026	Kaplan-Meier Survival Analysis
LGG	0.00084	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

PRI

Literatures

Expression

Transcripts

Gene Model

Pathway

PPI

Paralog

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000215301 (Gene tree)
Gene ID: 1654
Gene Symbol: DDX3X
Alias: DBX|HLP2|DDX14|DDX3
Full Name: DEAD-box helicase 3 X-linked
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Plus strand
Length: 31,189 bases
Position: chrX:41,333,284-41,364,472
Accession: 2745
Summary: The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000494887	DEAD	PF00270.29	5.4e-51	1	1
ENSP00000493795	DEAD	PF00270.29	5.5e-51	1	1
ENSP00000496052	DEAD	PF00270.29	5.5e-51	1	1
ENSP00000496356	DEAD	PF00270.29	5.5e-51	1	1
ENSP00000494518	DEAD	PF00270.29	1.2e-50	1	1
ENSP00000496524	DEAD	PF00270.29	1.2e-50	1	1
ENSP00000486443	DEAD	PF00270.29	1.3e-50	1	1
ENSP00000496222	DEAD	PF00270.29	1.3e-50	1	1
ENSP00000392494	DEAD	PF00270.29	1.3e-50	1	1
ENSP00000493475	DEAD	PF00270.29	1.3e-50	1	1
ENSP00000496663	DEAD	PF00270.29	1.4e-50	1	1
ENSP00000495377	DEAD	PF00270.29	1.4e-50	1	1
ENSP00000382840	DEAD	PF00270.29	1.4e-50	1	1
ENSP00000493819	DEAD	PF00270.29	1.4e-50	1	1
ENSP00000487224	DEAD	PF00270.29	1.4e-50	1	1
ENSP00000494040	DEAD	PF00270.29	1.4e-50	1	1
ENSP00000486306	DEAD	PF00270.29	1.8e-50	1	1
ENSP00000494952	DEAD	PF00270.29	3e-46	1	2
ENSP00000494952	DEAD	PF00270.29	3e-46	2	2
ENSP00000414281	DEAD	PF00270.29	1.8e-38	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	polyT & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

RNA-binding sites

Click here to download all RNA binding sites

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
27586307	DDX3X promotes the biogenesis of a subset of miRNAs and the potential roles they played in cancer development.	Sci Rep	2016 Sep 2	Zhao L	doi: 10.1038/srep32739.
18854321	Recruitment of the RNA helicase RHAU to stress granules via a unique RNA-binding domain.	J Biol Chem	2008 Dec 12	Chalupnikova K	doi: 10.1074/jbc.M804857200
22300661	Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: towards the next generation HIV-1 inhibitors.	Bioorg Med Chem Lett	2012 Mar 1	Radi M	doi: 10.1016/j.bmcl.2011.12.135
30950714	-	-	-	-	-
10074132	Hepatitis C virus core protein interacts with cellular putative RNA helicase.	J Virol	1999 Apr	You LR	-
17631897	Crystal structure of conserved domains 1 and 2 of the human DEAD-box helicase DDX3X in complex with the mononucleotide AMP.	J Mol Biol	2007 Sep 7	Hogbom M	-
24608801	RNA binding protein-mediated post-transcriptional gene regulation in medulloblastoma.	Mol Cells	2014 May	Bish R	doi: 10.14348/molcells.2014.0008
26544088	Homology Model-Based Virtual Screening for the Identification of Human Helicase DDX3 Inhibitors.	J Chem Inf Model	2015 Nov 23	Fazi R	doi: 10.1021/acs.jcim.5b00419
29062139	DDX3 regulates endoplasmic reticulum stress-induced ATF4 expression.	Sci Rep	2017 Oct 23	Adjibade P	doi: 10.1038/s41598-017-14262-7.
30256975	Analysis of NRAS RNA G-quadruplex binding proteins reveals DDX3X as a novel interactor of cellular G-quadruplex containing transcripts.	Nucleic Acids Res	2018 Nov 30	Herdy B	doi: 10.1093/nar/gky861.
30910425	HIV-1 gRNA, a biological substrate, uncovers the potency of DDX3X biochemical activity.	Biochimie	2019 Mar 22	de Bisschop G	doi: 10.1016/j.biochi.2019.03.008
24965446	Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.	J Virol	2014 Sep	Jefferson M	doi: 10.1128/JVI.00984-14
23449408	[Innate immune responses against viral infection and its suppression by viral proteins].	Yakugaku Zasshi	2013	Oshiumi H	-
24180280	Stimulation of DDX3 expression by ginsenoside Rg3 through the Akt/p53 pathway activates the innate immune response via TBK1/IKK-epsilon/IRF3 signalling.	Curr Med Chem	2014	Choi YJ	-
15312650	Kinesin transports RNA: isolation and characterization of an RNA-transporting granule.	Neuron	2004 Aug 19	Kanai Y	-
19913487	Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7.	Structure	2009 Nov 11	Oda S	doi: 10.1016/j.str.2009.09.005.
18845156	Poxvirus K7 protein adopts a Bcl-2 fold: biochemical mapping of its interactions with human DEAD box RNA helicase DDX3.	J Mol Biol	2009 Jan 23	Kalverda AP	doi: 10.1016/j.jmb.2008.09.048
21589879	A motif unique to the human DEAD-box protein DDX3 is important for nucleic acid binding, ATP hydrolysis, RNA/DNA unwinding and HIV-1 replication.	PLoS One	2011 May 12	Garbelli A	doi: 10.1371/journal.pone.0019810.
23218444	Can tobacco use promote HCV-induced miR-122 hijacking and hepatocarcinogenesis?	Med Hypotheses	2013 Feb	Zhao L	doi: 10.1016/j.mehy.2012.11.009
27736973	The DEAD-Box RNA Helicase DDX3 Interacts with NF-kB Subunit p65 and Suppresses p65-Mediated Transcription.	PLoS One	2016 Oct 13	Xiang N	doi: 10.1371/journal.pone.0164471
23630313	The DEAD-box helicase DDX3 substitutes for the cap-binding protein eIF4E to promote compartmentalized translation initiation of the HIV-1 genomic RNA.	Nucleic Acids Res	2013 Jul	Soto-Rifo R	doi: 10.1093/nar/gkt306
30684270	A 54-kDa short variant of DHX33 functions in regulating mRNA translation.	J Cell Physiol	2019 Jan 26	Su D	doi: 10.1002/jcp.28178
31178390	Metabolic stress activates an ERK/hnRNPK/DDX3X pathway in pancreatic -and-beta; cells.	Mol Metab	2019 May 24	Good AL	doi: 10.1016/j.molmet.2019.05.009

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000643963	DDX3X-236	4467	-	ENSP00000495264	193 (aa)	-	A0A2R8Y650
ENST00000644260	DDX3X-240	1059	-	-	- (aa)	-	-
ENST00000630255	DDX3X-219	3289	-	ENSP00000486720	662 (aa)	-	O00571
ENST00000644073	DDX3X-237	4349	-	ENSP00000493475	647 (aa)	-	A0A2R8YCW1
ENST00000644074	DDX3X-238	4620	-	ENSP00000496663	660 (aa)	-	A0A2R8YFR4
ENST00000645080	DDX3X-246	5594	-	ENSP00000494767	40 (aa)	-	A0A2R8YF31
ENST00000646679	DDX3X-263	4693	XM_017029314	ENSP00000494887	475 (aa)	XP_016884803	A0A2R8YDT5
ENST00000629785	DDX3X-218	3457	-	ENSP00000486516	662 (aa)	-	O00571
ENST00000647373	DDX3X-268	329	-	ENSP00000496076	48 (aa)	-	A0A2R8YGJ1
ENST00000642597	DDX3X-227	4327	-	-	- (aa)	-	-
ENST00000622198	DDX3X-213	608	-	-	- (aa)	-	-
ENST00000647219	DDX3X-266	522	-	-	- (aa)	-	-
ENST00000646107	DDX3X-256	4231	-	ENSP00000494518	622 (aa)	-	A0A2R8Y5G6
ENST00000645589	DDX3X-253	4239	-	ENSP00000494588	503 (aa)	-	A0A2R8YDH3
ENST00000611546	DDX3X-208	570	-	-	- (aa)	-	-
ENST00000616050	DDX3X-212	844	-	ENSP00000487626	222 (aa)	-	A0A0J9YVQ7
ENST00000610559	DDX3X-207	553	-	-	- (aa)	-	-
ENST00000644958	DDX3X-245	5817	-	-	- (aa)	-	-
ENST00000631641	DDX3X-222	1200	-	-	- (aa)	-	-
ENST00000645338	DDX3X-249	4698	-	-	- (aa)	-	-
ENST00000646940	DDX3X-265	4649	-	-	- (aa)	-	-
ENST00000642793	DDX3X-232	4596	-	ENSP00000493976	181 (aa)	-	A0A2R8YCU0
ENST00000630858	DDX3X-221	3181	-	ENSP00000486514	647 (aa)	-	A0A0D9SG12
ENST00000646122	DDX3X-257	4435	-	ENSP00000496222	641 (aa)	-	A0A2R8YF78
ENST00000646093	DDX3X-255	530	-	-	- (aa)	-	-
ENST00000645574	DDX3X-252	7284	-	-	- (aa)	-	-
ENST00000457138	DDX3X-203	4786	-	ENSP00000392494	646 (aa)	-	O00571
ENST00000646627	DDX3X-262	2469	-	ENSP00000493795	476 (aa)	-	A0A2R8Y7T2
ENST00000646822	DDX3X-264	5071	-	-	- (aa)	-	-
ENST00000615313	DDX3X-210	570	-	ENSP00000496257	96 (aa)	-	A0A2R8YF89
ENST00000644876	DDX3X-244	6907	-	ENSP00000494040	662 (aa)	-	O00571
ENST00000480592	DDX3X-205	2333	NR_126094	-	- (aa)	-	-
ENST00000645561	DDX3X-251	5340	-	-	- (aa)	-	-
ENST00000645783	DDX3X-254	1441	-	ENSP00000494905	40 (aa)	-	A0A2R8YF31
ENST00000642624	DDX3X-228	710	-	-	- (aa)	-	-
ENST00000615742	DDX3X-211	485	-	ENSP00000480647	98 (aa)	-	A0A087WX09
ENST00000642424	DDX3X-225	5789	-	ENSP00000496356	476 (aa)	-	A0A2R8Y7T2
ENST00000644513	DDX3X-242	4245	-	ENSP00000493819	662 (aa)	-	A0A2R8Y4A4
ENST00000478993	DDX3X-204	3397	-	ENSP00000478443	662 (aa)	-	O00571
ENST00000646196	DDX3X-258	5493	-	-	- (aa)	-	-
ENST00000622373	DDX3X-214	2129	-	-	- (aa)	-	-
ENST00000644109	DDX3X-239	4409	-	ENSP00000494952	716 (aa)	-	A0A2R8Y645
ENST00000399959	DDX3X-201	4632	-	ENSP00000382840	661 (aa)	-	A0A2U3TZJ9
ENST00000644677	DDX3X-243	4457	-	ENSP00000496524	622 (aa)	-	A0A2R8Y5G6
ENST00000646319	DDX3X-260	4554	XM_011543892	ENSP00000495377	661 (aa)	XP_011542194	A0A2R8YFS5
ENST00000642589	DDX3X-226	7473	-	-	- (aa)	-	-
ENST00000642322	DDX3X-224	4273	XM_017029313	ENSP00000496052	476 (aa)	XP_016884802	A0A2R8Y7T2
ENST00000647286	DDX3X-267	4257	-	-	- (aa)	-	-
ENST00000647477	DDX3X-269	3377	-	-	- (aa)	-	-
ENST00000441189	DDX3X-202	4122	-	ENSP00000414281	629 (aa)	-	F6S8Q4
ENST00000626301	DDX3X-216	3013	-	ENSP00000486443	640 (aa)	-	A0A0D9SFB3
ENST00000611968	DDX3X-209	782	-	ENSP00000479790	189 (aa)	-	A0A087WVZ1
ENST00000642687	DDX3X-229	4508	-	-	- (aa)	-	-
ENST00000646390	DDX3X-261	5141	-	-	- (aa)	-	-
ENST00000629496	DDX3X-217	5036	-	ENSP00000487224	662 (aa)	-	O00571
ENST00000542215	DDX3X-206	1592	-	ENSP00000493687	78 (aa)	-	A0A2R8Y4D2
ENST00000642763	DDX3X-231	2940	-	-	- (aa)	-	-
ENST00000642161	DDX3X-223	6724	-	-	- (aa)	-	-
ENST00000645253	DDX3X-248	2049	-	-	- (aa)	-	-
ENST00000645120	DDX3X-247	5651	-	-	- (aa)	-	-
ENST00000646223	DDX3X-259	6203	-	ENSP00000496043	61 (aa)	-	A0A2R8Y770
ENST00000642722	DDX3X-230	4989	-	-	- (aa)	-	-
ENST00000644307	DDX3X-241	4605	-	-	- (aa)	-	-
ENST00000625837	DDX3X-215	3237	-	ENSP00000486306	733 (aa)	-	A0A0D9SF53
ENST00000630370	DDX3X-220	3120	-	ENSP00000487062	647 (aa)	-	A0A0D9SG12
ENST00000642801	DDX3X-233	4116	-	-	- (aa)	-	-
ENST00000643821	DDX3X-235	1434	-	ENSP00000493997	40 (aa)	-	A0A2R8YF31
ENST00000643820	DDX3X-234	1331	-	-	- (aa)	-	-
ENST00000645380	DDX3X-250	5617	-	-	- (aa)	-	-

Gene Model

Click here to download 's gene model file

Pathway

Pathway ID	Pathway Name	Source
hsa04622	RIG-I-like receptor signaling pathway	KEGG
hsa05161	Hepatitis B	KEGG
hsa05203	Viral carcinogenesis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000215301's network

Paralog

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000215301	DDX3X	73	31.161	ENSG00000136271	DDX56	91	33.333
ENSG00000215301	DDX3X	98	41.260	ENSG00000100201	DDX17	63	65.714
ENSG00000215301	DDX3X	75	33.520	ENSG00000123064	DDX54	84	35.196
ENSG00000215301	DDX3X	72	32.044	ENSG00000109832	DDX25	89	32.044
ENSG00000215301	DDX3X	79	30.052	ENSG00000198563	DDX39B	99	30.116
ENSG00000215301	DDX3X	100	95.588	ENSG00000067048	DDX3Y	100	91.843
ENSG00000215301	DDX3X	74	32.153	ENSG00000157349	DDX19B	92	31.880
ENSG00000215301	DDX3X	74	36.441	ENSG00000213782	DDX47	89	32.796
ENSG00000215301	DDX3X	75	36.740	ENSG00000141543	EIF4A3	90	34.577
ENSG00000215301	DDX3X	85	39.312	ENSG00000080007	DDX43	60	39.312
ENSG00000215301	DDX3X	83	30.789	ENSG00000110367	DDX6	76	30.789
ENSG00000215301	DDX3X	59	36.567	ENSG00000089737	DDX24	66	32.110
ENSG00000215301	DDX3X	78	33.244	ENSG00000156976	EIF4A2	93	31.667
ENSG00000215301	DDX3X	74	31.880	ENSG00000168872	DDX19A	86	31.880
ENSG00000215301	DDX3X	80	33.505	ENSG00000278053	DDX52	74	32.819
ENSG00000215301	DDX3X	87	34.615	ENSG00000118197	DDX59	99	34.802
ENSG00000215301	DDX3X	79	31.496	ENSG00000123136	DDX39A	97	39.785
ENSG00000215301	DDX3X	98	40.756	ENSG00000108654	DDX5	93	54.430
ENSG00000215301	DDX3X	84	40.196	ENSG00000183258	DDX41	62	46.154
ENSG00000215301	DDX3X	75	33.957	ENSG00000111364	DDX55	88	37.569
ENSG00000215301	DDX3X	80	31.282	ENSG00000178105	DDX10	55	31.658
ENSG00000215301	DDX3X	72	34.648	ENSG00000165732	DDX21	60	31.416
ENSG00000215301	DDX3X	83	38.995	ENSG00000174243	DDX23	51	42.308
ENSG00000215301	DDX3X	74	35.097	ENSG00000105671	DDX49	70	35.097
ENSG00000215301	DDX3X	71	34.412	ENSG00000088205	DDX18	79	33.333
ENSG00000215301	DDX3X	89	36.977	ENSG00000198231	DDX42	57	37.674
ENSG00000215301	DDX3X	78	32.976	ENSG00000161960	EIF4A1	100	35.326
ENSG00000215301	DDX3X	91	51.945	ENSG00000152670	DDX4	77	52.980
ENSG00000215301	DDX3X	83	36.364	ENSG00000184735	DDX53	60	36.364
ENSG00000215301	DDX3X	75	36.986	ENSG00000124228	DDX27	82	31.174

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000215301	DDX3X	85	89.894	ENSAPOG00000019437	-	99	73.167	Acanthochromis_polyacanthus
ENSG00000215301	DDX3X	100	86.458	ENSAPOG00000003652	-	100	72.055	Acanthochromis_polyacanthus
ENSG00000215301	DDX3X	100	100.000	ENSAMEG00000006801	DDX3X	98	99.849	Ailuropoda_melanoleuca
ENSG00000215301	DDX3X	100	84.551	ENSACIG00000013354	-	93	82.404	Amphilophus_citrinellus
ENSG00000215301	DDX3X	91	88.863	ENSACIG00000023986	-	86	80.138	Amphilophus_citrinellus
ENSG00000215301	DDX3X	100	86.458	ENSAOCG00000002188	-	100	71.841	Amphiprion_ocellaris
ENSG00000215301	DDX3X	99	68.551	ENSAOCG00000018576	-	99	67.003	Amphiprion_ocellaris
ENSG00000215301	DDX3X	100	84.551	ENSAPEG00000005976	-	94	82.609	Amphiprion_percula
ENSG00000215301	DDX3X	100	86.458	ENSAPEG00000020102	-	100	69.312	Amphiprion_percula
ENSG00000215301	DDX3X	100	85.625	ENSATEG00000019116	-	100	70.380	Anabas_testudineus
ENSG00000215301	DDX3X	99	85.504	ENSATEG00000019608	-	96	69.494	Anabas_testudineus
ENSG00000215301	DDX3X	100	96.436	ENSAPLG00000014240	-	98	90.046	Anas_platyrhynchos
ENSG00000215301	DDX3X	100	91.476	ENSACAG00000017928	-	100	81.037	Anolis_carolinensis
ENSG00000215301	DDX3X	100	100.000	ENSANAG00000017441	DDX3X	100	99.546	Aotus_nancymaae
ENSG00000215301	DDX3X	100	88.000	ENSANAG00000000067	-	99	87.784	Aotus_nancymaae
ENSG00000215301	DDX3X	100	84.792	ENSACLG00000013517	-	100	71.193	Astatotilapia_calliptera
ENSG00000215301	DDX3X	100	85.625	ENSACLG00000003774	-	100	70.508	Astatotilapia_calliptera
ENSG00000215301	DDX3X	100	86.947	ENSAMXG00000013396	ddx3xb	99	81.171	Astyanax_mexicanus
ENSG00000215301	DDX3X	100	81.223	ENSAMXG00000032415	ddx3xa	100	69.012	Astyanax_mexicanus
ENSG00000215301	DDX3X	100	99.580	ENSBTAG00000035907	DDX3X	100	98.943	Bos_taurus
ENSG00000215301	DDX3X	100	100.000	ENSCJAG00000015787	DDX3X	100	100.000	Callithrix_jacchus
ENSG00000215301	DDX3X	99	76.042	ENSCJAG00000048678	-	99	81.893	Callithrix_jacchus
ENSG00000215301	DDX3X	100	100.000	ENSCAFG00000014251	DDX3X	100	99.849	Canis_familiaris
ENSG00000215301	DDX3X	100	100.000	ENSCAFG00020027227	DDX3X	100	99.849	Canis_lupus_dingo
ENSG00000215301	DDX3X	100	96.000	ENSCHIG00000010585	-	100	92.447	Capra_hircus
ENSG00000215301	DDX3X	91	88.764	ENSCHIG00000000047	-	95	84.141	Capra_hircus
ENSG00000215301	DDX3X	100	99.790	ENSCHIG00000024903	-	100	99.094	Capra_hircus
ENSG00000215301	DDX3X	100	99.448	ENSTSYG00000003895	DDX3X	100	94.573	Carlito_syrichta
ENSG00000215301	DDX3X	100	93.277	ENSTSYG00000029157	-	98	89.255	Carlito_syrichta
ENSG00000215301	DDX3X	100	92.842	ENSCAPG00000010945	-	98	89.368	Cavia_aperea
ENSG00000215301	DDX3X	89	94.444	ENSCAPG00000014373	-	100	78.550	Cavia_aperea
ENSG00000215301	DDX3X	100	92.842	ENSCPOG00000020978	-	98	89.026	Cavia_porcellus
ENSG00000215301	DDX3X	89	94.444	ENSCPOG00000039190	-	100	79.305	Cavia_porcellus
ENSG00000215301	DDX3X	100	98.739	ENSCPOG00000013557	-	98	97.994	Cavia_porcellus
ENSG00000215301	DDX3X	100	100.000	ENSCCAG00000023934	DDX3X	100	100.000	Cebus_capucinus
ENSG00000215301	DDX3X	100	91.789	ENSCCAG00000000872	-	100	85.370	Cebus_capucinus
ENSG00000215301	DDX3X	100	89.263	ENSCCAG00000036904	-	100	87.255	Cebus_capucinus
ENSG00000215301	DDX3X	100	100.000	ENSCATG00000010148	DDX3X	100	100.000	Cercocebus_atys
ENSG00000215301	DDX3X	100	97.790	ENSCLAG00000000993	DDX3X	100	96.526	Chinchilla_lanigera
ENSG00000215301	DDX3X	100	96.000	ENSCSAG00000018317	DDX3Y	100	92.900	Chlorocebus_sabaeus
ENSG00000215301	DDX3X	100	100.000	ENSCSAG00000013949	DDX3X	91	97.037	Chlorocebus_sabaeus
ENSG00000215301	DDX3X	94	99.043	ENSCHOG00000011076	DDX3X	83	99.574	Choloepus_hoffmanni
ENSG00000215301	DDX3X	100	92.958	ENSCPBG00000019916	-	100	88.905	Chrysemys_picta_bellii
ENSG00000215301	DDX3X	100	100.000	ENSCANG00000031127	DDX3X	100	100.000	Colobus_angolensis_palliatus
ENSG00000215301	DDX3X	100	98.950	ENSCGRG00001022185	Ddx3x	100	98.640	Cricetulus_griseus_chok1gshd
ENSG00000215301	DDX3X	100	97.275	ENSCGRG00001002373	D1Pas1	99	93.982	Cricetulus_griseus_chok1gshd
ENSG00000215301	DDX3X	100	98.950	ENSCGRG00000010880	Ddx3x	100	98.640	Cricetulus_griseus_crigri
ENSG00000215301	DDX3X	100	85.177	ENSCSEG00000000900	-	100	70.233	Cynoglossus_semilaevis
ENSG00000215301	DDX3X	99	83.507	ENSCSEG00000003352	-	86	76.221	Cynoglossus_semilaevis
ENSG00000215301	DDX3X	100	85.625	ENSCVAG00000001784	-	100	73.438	Cyprinodon_variegatus
ENSG00000215301	DDX3X	100	85.000	ENSCVAG00000011003	-	82	78.723	Cyprinodon_variegatus
ENSG00000215301	DDX3X	100	85.386	ENSDARG00000005774	ddx3xb	99	89.153	Danio_rerio
ENSG00000215301	DDX3X	89	88.811	ENSDARG00000020573	ddx3xa	100	70.222	Danio_rerio
ENSG00000215301	DDX3X	100	99.790	ENSDNOG00000007452	-	99	99.502	Dasypus_novemcinctus
ENSG00000215301	DDX3X	100	97.238	ENSDNOG00000005693	-	100	96.979	Dasypus_novemcinctus
ENSG00000215301	DDX3X	100	97.790	ENSDORG00000029882	Ddx3x	99	96.218	Dipodomys_ordii
ENSG00000215301	DDX3X	100	96.849	ENSETEG00000006882	DDX3X	87	96.881	Echinops_telfairi
ENSG00000215301	DDX3X	99	68.182	ENSEBUG00000007692	ddx3xa	97	68.371	Eptatretus_burgeri
ENSG00000215301	DDX3X	100	100.000	ENSEASG00005009841	DDX3X	100	100.000	Equus_asinus_asinus
ENSG00000215301	DDX3X	100	97.684	ENSEASG00005012087	DDX3Y	100	95.015	Equus_asinus_asinus
ENSG00000215301	DDX3X	100	100.000	ENSECAG00000009901	DDX3X	100	99.849	Equus_caballus
ENSG00000215301	DDX3X	100	98.739	ENSEEUG00000002817	DDX3X	100	98.300	Erinaceus_europaeus
ENSG00000215301	DDX3X	100	85.093	ENSELUG00000004613	-	100	70.137	Esox_lucius
ENSG00000215301	DDX3X	100	81.705	ENSELUG00000023518	-	100	69.494	Esox_lucius
ENSG00000215301	DDX3X	100	100.000	ENSFCAG00000025339	DDX3X	100	100.000	Felis_catus
ENSG00000215301	DDX3X	100	96.017	ENSFALG00000001530	-	97	93.860	Ficedula_albicollis
ENSG00000215301	DDX3X	85	88.235	ENSFDAG00000006053	-	99	64.165	Fukomys_damarensis
ENSG00000215301	DDX3X	100	91.579	ENSFDAG00000013328	DDX3Y	100	88.941	Fukomys_damarensis
ENSG00000215301	DDX3X	100	98.319	ENSFDAG00000011500	-	100	98.187	Fukomys_damarensis
ENSG00000215301	DDX3X	100	79.245	ENSFHEG00000012643	-	100	70.788	Fundulus_heteroclitus
ENSG00000215301	DDX3X	100	85.239	ENSFHEG00000010407	-	100	76.331	Fundulus_heteroclitus
ENSG00000215301	DDX3X	100	78.631	ENSGMOG00000003944	DDX3X	97	80.405	Gadus_morhua
ENSG00000215301	DDX3X	100	95.798	ENSGALG00000016231	DDX3X	100	89.925	Gallus_gallus
ENSG00000215301	DDX3X	100	86.042	ENSGAFG00000022047	-	100	72.908	Gambusia_affinis
ENSG00000215301	DDX3X	100	82.708	ENSGAFG00000003155	ddx3xb	100	72.779	Gambusia_affinis
ENSG00000215301	DDX3X	100	77.178	ENSGACG00000014407	-	100	65.837	Gasterosteus_aculeatus
ENSG00000215301	DDX3X	100	78.571	ENSGACG00000008206	-	100	68.000	Gasterosteus_aculeatus
ENSG00000215301	DDX3X	100	92.516	ENSGAGG00000004207	-	100	83.584	Gopherus_agassizii
ENSG00000215301	DDX3X	100	100.000	ENSGGOG00000003181	DDX3X	100	100.000	Gorilla_gorilla
ENSG00000215301	DDX3X	100	85.417	ENSHBUG00000002311	-	92	82.821	Haplochromis_burtoni
ENSG00000215301	DDX3X	100	85.625	ENSHBUG00000009486	-	100	70.508	Haplochromis_burtoni
ENSG00000215301	DDX3X	100	96.008	ENSHGLG00000010084	-	100	95.015	Heterocephalus_glaber_female
ENSG00000215301	DDX3X	100	98.343	ENSHGLG00000004805	Ddx3x	100	98.033	Heterocephalus_glaber_female
ENSG00000215301	DDX3X	100	68.842	ENSHGLG00100013600	-	99	68.146	Heterocephalus_glaber_male
ENSG00000215301	DDX3X	100	87.525	ENSHGLG00100000759	-	94	88.099	Heterocephalus_glaber_male
ENSG00000215301	DDX3X	100	98.410	ENSHGLG00100005685	-	100	97.885	Heterocephalus_glaber_male
ENSG00000215301	DDX3X	100	97.651	ENSHGLG00100005604	-	99	98.788	Heterocephalus_glaber_male
ENSG00000215301	DDX3X	100	84.969	ENSHCOG00000006275	-	100	62.740	Hippocampus_comes
ENSG00000215301	DDX3X	100	85.625	ENSHCOG00000016890	-	100	71.706	Hippocampus_comes
ENSG00000215301	DDX3X	100	84.134	ENSIPUG00000009936	ddx3xb	100	73.752	Ictalurus_punctatus
ENSG00000215301	DDX3X	100	83.093	ENSIPUG00000023024	ddx3xa	100	69.262	Ictalurus_punctatus
ENSG00000215301	DDX3X	100	99.580	ENSSTOG00000008094	DDX3X	94	99.074	Ictidomys_tridecemlineatus
ENSG00000215301	DDX3X	100	98.343	ENSJJAG00000019645	Ddx3x	100	97.285	Jaculus_jaculus
ENSG00000215301	DDX3X	99	84.454	ENSKMAG00000012633	-	99	70.376	Kryptolebias_marmoratus
ENSG00000215301	DDX3X	100	85.833	ENSKMAG00000011081	-	100	74.006	Kryptolebias_marmoratus
ENSG00000215301	DDX3X	91	88.372	ENSLBEG00000012311	-	97	76.098	Labrus_bergylta
ENSG00000215301	DDX3X	100	83.716	ENSLBEG00000016034	-	98	70.978	Labrus_bergylta
ENSG00000215301	DDX3X	85	92.138	ENSLACG00000007753	ddx3xa	99	75.712	Latimeria_chalumnae
ENSG00000215301	DDX3X	100	86.611	ENSLOCG00000002122	ddx3xa	100	74.658	Lepisosteus_oculatus
ENSG00000215301	DDX3X	100	99.160	ENSLAFG00000017378	DDX3X	100	98.943	Loxodonta_africana
ENSG00000215301	DDX3X	100	100.000	ENSMFAG00000034876	DDX3X	100	100.000	Macaca_fascicularis
ENSG00000215301	DDX3X	100	95.789	ENSMMUG00000043966	DDX3Y	100	93.051	Macaca_mulatta
ENSG00000215301	DDX3X	100	100.000	ENSMMUG00000017569	DDX3X	100	100.000	Macaca_mulatta
ENSG00000215301	DDX3X	100	100.000	ENSMNEG00000031741	DDX3X	100	100.000	Macaca_nemestrina
ENSG00000215301	DDX3X	100	100.000	ENSMLEG00000044178	DDX3X	100	100.000	Mandrillus_leucophaeus
ENSG00000215301	DDX3X	100	85.270	ENSMAMG00000013070	-	100	70.685	Mastacembelus_armatus
ENSG00000215301	DDX3X	100	85.177	ENSMAMG00000021938	-	100	70.645	Mastacembelus_armatus
ENSG00000215301	DDX3X	100	85.625	ENSMZEG00005020636	-	90	81.193	Maylandia_zebra
ENSG00000215301	DDX3X	100	85.625	ENSMZEG00005008814	-	100	70.508	Maylandia_zebra
ENSG00000215301	DDX3X	100	96.226	ENSMGAG00000014609	-	98	90.031	Meleagris_gallopavo
ENSG00000215301	DDX3X	100	97.474	ENSMAUG00000000329	D1Pas1	100	93.253	Mesocricetus_auratus
ENSG00000215301	DDX3X	100	98.950	ENSMAUG00000021962	Ddx3x	100	98.640	Mesocricetus_auratus
ENSG00000215301	DDX3X	98	77.660	ENSMICG00000045639	-	99	74.267	Microcebus_murinus
ENSG00000215301	DDX3X	100	99.580	ENSMICG00000032772	DDX3X	100	99.094	Microcebus_murinus
ENSG00000215301	DDX3X	100	98.950	ENSMOCG00000014170	Ddx3x	100	98.640	Microtus_ochrogaster
ENSG00000215301	DDX3X	100	97.269	ENSMOCG00000002596	D1Pas1	100	93.363	Microtus_ochrogaster
ENSG00000215301	DDX3X	100	84.134	ENSMMOG00000006355	-	100	71.835	Mola_mola
ENSG00000215301	DDX3X	100	86.250	ENSMMOG00000004744	-	100	74.496	Mola_mola
ENSG00000215301	DDX3X	100	98.536	ENSMODG00000021097	-	100	98.536	Monodelphis_domestica
ENSG00000215301	DDX3X	91	86.139	ENSMALG00000020239	-	87	74.786	Monopterus_albus
ENSG00000215301	DDX3X	100	82.851	ENSMALG00000016484	-	93	78.849	Monopterus_albus
ENSG00000215301	DDX3X	100	98.319	MGP_CAROLIEiJ_G0032941	Ddx3x	100	98.036	Mus_caroli
ENSG00000215301	DDX3X	100	97.474	MGP_CAROLIEiJ_G0015028	D1Pas1	100	95.015	Mus_caroli
ENSG00000215301	DDX3X	100	98.950	ENSMUSG00000000787	Ddx3x	100	98.640	Mus_musculus
ENSG00000215301	DDX3X	100	93.684	ENSMUSG00000069045	Ddx3y	100	89.275	Mus_musculus
ENSG00000215301	DDX3X	100	97.684	ENSMUSG00000039224	D1Pas1	100	95.015	Mus_musculus
ENSG00000215301	DDX3X	100	98.950	MGP_PahariEiJ_G0031487	Ddx3x	100	98.640	Mus_pahari
ENSG00000215301	DDX3X	100	97.684	MGP_PahariEiJ_G0028260	D1Pas1	100	95.015	Mus_pahari
ENSG00000215301	DDX3X	100	97.684	MGP_SPRETEiJ_G0015828	D1Pas1	100	95.015	Mus_spretus
ENSG00000215301	DDX3X	100	100.000	ENSMPUG00000012631	DDX3X	100	99.849	Mustela_putorius_furo
ENSG00000215301	DDX3X	100	98.950	ENSMLUG00000010216	DDX3X	98	98.489	Myotis_lucifugus
ENSG00000215301	DDX3X	100	98.950	ENSNGAG00000018077	Ddx3x	100	98.792	Nannospalax_galili
ENSG00000215301	DDX3X	100	82.696	ENSNBRG00000019630	-	100	67.425	Neolamprologus_brichardi
ENSG00000215301	DDX3X	100	85.833	ENSNBRG00000020448	-	89	77.379	Neolamprologus_brichardi
ENSG00000215301	DDX3X	100	100.000	ENSNLEG00000001876	DDX3X	100	95.619	Nomascus_leucogenys
ENSG00000215301	DDX3X	98	97.273	ENSMEUG00000006501	-	100	89.831	Notamacropus_eugenii
ENSG00000215301	DDX3X	100	83.264	ENSOPRG00000004720	DDX3X	100	77.350	Ochotona_princeps
ENSG00000215301	DDX3X	99	66.600	ENSODEG00000001314	-	98	71.924	Octodon_degus
ENSG00000215301	DDX3X	100	98.739	ENSODEG00000001355	-	100	98.489	Octodon_degus
ENSG00000215301	DDX3X	100	84.600	ENSONIG00000016252	-	100	72.462	Oreochromis_niloticus
ENSG00000215301	DDX3X	100	85.595	ENSONIG00000015293	-	100	72.039	Oreochromis_niloticus
ENSG00000215301	DDX3X	100	98.125	ENSOANG00000011274	-	99	96.229	Ornithorhynchus_anatinus
ENSG00000215301	DDX3X	100	99.580	ENSOCUG00000012338	DDX3X	100	99.245	Oryctolagus_cuniculus
ENSG00000215301	DDX3X	100	84.583	ENSORLG00000013621	-	100	75.474	Oryzias_latipes
ENSG00000215301	DDX3X	100	81.250	ENSORLG00000025640	-	100	67.838	Oryzias_latipes
ENSG00000215301	DDX3X	100	84.244	ENSORLG00020008144	-	100	73.163	Oryzias_latipes_hni
ENSG00000215301	DDX3X	60	82.979	ENSORLG00020008350	-	83	69.399	Oryzias_latipes_hni
ENSG00000215301	DDX3X	100	84.583	ENSORLG00015011027	-	100	75.328	Oryzias_latipes_hsok
ENSG00000215301	DDX3X	100	81.048	ENSORLG00015011446	-	100	67.838	Oryzias_latipes_hsok
ENSG00000215301	DDX3X	71	87.537	ENSOMEG00000006456	-	98	88.768	Oryzias_melastigma
ENSG00000215301	DDX3X	100	85.000	ENSOMEG00000007983	-	100	75.328	Oryzias_melastigma
ENSG00000215301	DDX3X	100	99.370	ENSOGAG00000005311	DDX3X	100	99.094	Otolemur_garnettii
ENSG00000215301	DDX3X	100	99.790	ENSOARG00000002433	DDX3X	100	99.094	Ovis_aries
ENSG00000215301	DDX3X	100	100.000	ENSPPAG00000041809	DDX3X	100	99.849	Pan_paniscus
ENSG00000215301	DDX3X	100	100.000	ENSPPRG00000005269	DDX3X	100	100.000	Panthera_pardus
ENSG00000215301	DDX3X	100	96.842	ENSPTIG00000016749	DDX3Y	95	94.904	Panthera_tigris_altaica
ENSG00000215301	DDX3X	100	100.000	ENSPTIG00000014814	DDX3X	100	98.338	Panthera_tigris_altaica
ENSG00000215301	DDX3X	100	95.168	ENSPTRG00000022488	DDX3Y	100	92.013	Pan_troglodytes
ENSG00000215301	DDX3X	100	100.000	ENSPTRG00000049651	DDX3X	100	99.845	Pan_troglodytes
ENSG00000215301	DDX3X	100	100.000	ENSPANG00000023917	DDX3X	100	100.000	Papio_anubis
ENSG00000215301	DDX3X	100	86.947	ENSPKIG00000004320	-	99	82.979	Paramormyrops_kingsleyae
ENSG00000215301	DDX3X	100	86.105	ENSPKIG00000003617	ddx3xa	98	80.892	Paramormyrops_kingsleyae
ENSG00000215301	DDX3X	100	95.426	ENSPSIG00000011217	-	100	91.181	Pelodiscus_sinensis
ENSG00000215301	DDX3X	100	83.716	ENSPMGG00000019844	-	100	70.745	Periophthalmus_magnuspinnatus
ENSG00000215301	DDX3X	100	99.160	ENSPEMG00000014021	Ddx3x	100	98.640	Peromyscus_maniculatus_bairdii
ENSG00000215301	DDX3X	100	97.684	ENSPEMG00000010847	D1Pas1	100	94.411	Peromyscus_maniculatus_bairdii
ENSG00000215301	DDX3X	100	98.745	ENSPCIG00000000219	-	100	97.892	Phascolarctos_cinereus
ENSG00000215301	DDX3X	100	85.625	ENSPFOG00000009850	-	100	72.867	Poecilia_formosa
ENSG00000215301	DDX3X	100	81.250	ENSPFOG00000004599	-	100	68.606	Poecilia_formosa
ENSG00000215301	DDX3X	100	85.177	ENSPLAG00000006604	-	99	78.219	Poecilia_latipinna
ENSG00000215301	DDX3X	100	86.042	ENSPLAG00000005920	-	100	73.617	Poecilia_latipinna
ENSG00000215301	DDX3X	91	89.327	ENSPMEG00000014025	-	92	83.304	Poecilia_mexicana
ENSG00000215301	DDX3X	100	84.342	ENSPMEG00000006724	-	100	70.637	Poecilia_mexicana
ENSG00000215301	DDX3X	100	86.250	ENSPREG00000020880	-	100	78.092	Poecilia_reticulata
ENSG00000215301	DDX3X	100	84.342	ENSPREG00000012291	-	100	70.914	Poecilia_reticulata
ENSG00000215301	DDX3X	100	100.000	ENSPPYG00000020257	DDX3X	100	100.000	Pongo_abelii
ENSG00000215301	DDX3X	100	98.950	ENSPCAG00000007534	DDX3X	99	98.305	Procavia_capensis
ENSG00000215301	DDX3X	100	99.370	ENSPCOG00000027628	DDX3X	100	99.245	Propithecus_coquereli
ENSG00000215301	DDX3X	100	99.448	ENSPVAG00000014651	DDX3X	100	99.094	Pteropus_vampyrus
ENSG00000215301	DDX3X	100	85.625	ENSPNYG00000012338	-	100	69.583	Pundamilia_nyererei
ENSG00000215301	DDX3X	100	85.625	ENSPNYG00000002452	-	100	70.411	Pundamilia_nyererei
ENSG00000215301	DDX3X	100	79.084	ENSPNAG00000003714	ddx3xa	96	75.814	Pygocentrus_nattereri
ENSG00000215301	DDX3X	100	87.891	ENSPNAG00000010870	ddx3xb	100	72.940	Pygocentrus_nattereri
ENSG00000215301	DDX3X	100	99.160	ENSRNOG00000023383	Ddx3x	100	98.640	Rattus_norvegicus
ENSG00000215301	DDX3X	100	97.684	ENSRNOG00000002501	Ddx3y	100	95.461	Rattus_norvegicus
ENSG00000215301	DDX3X	100	92.842	ENSRNOG00000057231	Ddx3	100	89.074	Rattus_norvegicus
ENSG00000215301	DDX3X	98	99.462	ENSRBIG00000042259	DDX3X	100	97.767	Rhinopithecus_bieti
ENSG00000215301	DDX3X	99	90.020	ENSRBIG00000032422	DDX3Y	100	100.000	Rhinopithecus_bieti
ENSG00000215301	DDX3X	100	100.000	ENSRROG00000030233	DDX3X	99	99.845	Rhinopithecus_roxellana
ENSG00000215301	DDX3X	100	95.798	ENSRROG00000036763	DDX3Y	100	92.459	Rhinopithecus_roxellana
ENSG00000215301	DDX3X	100	99.789	ENSSBOG00000019095	-	100	99.697	Saimiri_boliviensis_boliviensis
ENSG00000215301	DDX3X	88	85.714	ENSSBOG00000025327	-	99	66.717	Saimiri_boliviensis_boliviensis
ENSG00000215301	DDX3X	100	97.917	ENSSHAG00000007623	-	99	97.147	Sarcophilus_harrisii
ENSG00000215301	DDX3X	100	85.386	ENSSFOG00015007587	-	100	76.056	Scleropages_formosus
ENSG00000215301	DDX3X	100	83.992	ENSSFOG00015022312	ddx3xa	100	70.245	Scleropages_formosus
ENSG00000215301	DDX3X	99	83.648	ENSSMAG00000012135	-	99	67.067	Scophthalmus_maximus
ENSG00000215301	DDX3X	100	83.824	ENSSMAG00000015674	-	99	77.110	Scophthalmus_maximus
ENSG00000215301	DDX3X	100	85.625	ENSSDUG00000013166	-	100	71.983	Seriola_dumerili
ENSG00000215301	DDX3X	99	85.504	ENSSDUG00000004279	-	99	77.496	Seriola_dumerili
ENSG00000215301	DDX3X	100	85.625	ENSSLDG00000018297	-	100	75.474	Seriola_lalandi_dorsalis
ENSG00000215301	DDX3X	99	85.504	ENSSLDG00000002762	-	98	70.621	Seriola_lalandi_dorsalis
ENSG00000215301	DDX3X	100	92.354	ENSSPUG00000005312	-	100	87.299	Sphenodon_punctatus
ENSG00000215301	DDX3X	99	84.454	ENSSPAG00000010225	-	97	71.250	Stegastes_partitus
ENSG00000215301	DDX3X	100	86.667	ENSSPAG00000018177	-	100	73.343	Stegastes_partitus
ENSG00000215301	DDX3X	100	97.474	ENSSSCG00000026430	DDX3Y	100	96.937	Sus_scrofa
ENSG00000215301	DDX3X	100	99.790	ENSSSCG00000012252	DDX3X	100	99.245	Sus_scrofa
ENSG00000215301	DDX3X	100	94.561	ENSTGUG00000006442	-	100	89.571	Taeniopygia_guttata
ENSG00000215301	DDX3X	100	85.000	ENSTRUG00000014001	-	100	76.048	Takifugu_rubripes
ENSG00000215301	DDX3X	100	83.299	ENSTRUG00000003862	-	100	68.750	Takifugu_rubripes
ENSG00000215301	DDX3X	84	88.770	ENSTNIG00000014514	-	100	83.784	Tetraodon_nigroviridis
ENSG00000215301	DDX3X	100	85.300	ENSTNIG00000011569	-	100	72.277	Tetraodon_nigroviridis
ENSG00000215301	DDX3X	100	99.370	ENSTTRG00000001906	DDX3X	100	98.454	Tursiops_truncatus
ENSG00000215301	DDX3X	100	98.526	ENSUAMG00000012970	-	100	96.677	Ursus_americanus
ENSG00000215301	DDX3X	100	100.000	ENSUAMG00000013185	DDX3X	95	99.843	Ursus_americanus
ENSG00000215301	DDX3X	100	100.000	ENSUMAG00000016796	DDX3X	98	100.000	Ursus_maritimus
ENSG00000215301	DDX3X	100	95.635	ENSUMAG00000010366	DDX3Y	86	96.854	Ursus_maritimus
ENSG00000215301	DDX3X	100	99.160	ENSVPAG00000007680	DDX3X	100	98.724	Vicugna_pacos
ENSG00000215301	DDX3X	100	100.000	ENSVVUG00000011589	DDX3X	100	99.849	Vulpes_vulpes
ENSG00000215301	DDX3X	100	97.684	ENSVVUG00000030358	DDX3Y	99	96.166	Vulpes_vulpes
ENSG00000215301	DDX3X	88	94.498	ENSXETG00000015477	ddx3x	100	80.395	Xenopus_tropicalis
ENSG00000215301	DDX3X	100	84.211	ENSXCOG00000017947	-	90	83.009	Xiphophorus_couchianus
ENSG00000215301	DDX3X	100	84.551	ENSXCOG00000020327	-	92	81.629	Xiphophorus_couchianus
ENSG00000215301	DDX3X	100	86.458	ENSXMAG00000006761	-	100	73.617	Xiphophorus_maculatus
ENSG00000215301	DDX3X	100	85.263	ENSXMAG00000002739	-	99	79.553	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003677	DNA binding	21589879.	IDA	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	21589879.	IDA	Function
GO:0003924	GTPase activity	10074132.	IDA	Function
GO:0004003	ATP-dependent DNA helicase activity	21589879.	IDA	Function
GO:0004004	ATP-dependent RNA helicase activity	21589879.	IDA	Function
GO:0005515	protein binding	10074132.10329544.10336476.17855521.18596238.18628297.18636090.18985028.19913487.20127681.20657822.20862261.21730191.21883093.22323517.22616990.22810585.22872150.23413191.23840900.24169621.24855944.26100019.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005576	extracellular region	-	TAS	Component
GO:0005634	nucleus	10074132.10329544.	IDA	Component
GO:0005737	cytoplasm	10329544.24965446.	IDA	Component
GO:0005737	cytoplasm	10074132.26100019.	IMP	Component
GO:0005741	mitochondrial outer membrane	-	IEA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005852	eukaryotic translation initiation factor 3 complex	18628297.	IDA	Component
GO:0006413	translational initiation	26100019.	IMP	Process
GO:0007059	chromosome segregation	21730191.	IMP	Process
GO:0008134	transcription factor binding	16818630.	IDA	Function
GO:0008143	poly(A) binding	18596238.	IDA	Function
GO:0008190	eukaryotic initiation factor 4E binding	17667941.	IDA	Function
GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	18846110.	IMP	Process
GO:0009615	response to virus	18636090.	IDA	Process
GO:0010494	cytoplasmic stress granule	18596238.21883093.	IDA	Component
GO:0010501	RNA secondary structure unwinding	22872150.	IDA	Process
GO:0010628	positive regulation of gene expression	10074132.	IDA	Process
GO:0016032	viral process	-	IEA	Process
GO:0016055	Wnt signaling pathway	26235985.	IMP	Process
GO:0016607	nuclear speck	-	IEA	Component
GO:0016887	ATPase activity	10074132.21589879.	IDA	Function
GO:0017111	nucleoside-triphosphatase activity	10074132.	IDA	Function
GO:0017148	negative regulation of translation	17667941.	IMP	Process
GO:0022627	cytosolic small ribosomal subunit	18596238.	IDA	Component
GO:0030307	positive regulation of cell growth	18628297.20837705.	IMP	Process
GO:0030308	negative regulation of cell growth	16818630.	IDA	Process
GO:0031333	negative regulation of protein complex assembly	17667941.	IDA	Process
GO:0031369	translation initiation factor binding	22323517.22872150.	IDA	Function
GO:0032508	DNA duplex unwinding	-	IEA	Process
GO:0032728	positive regulation of interferon-beta production	18583960.18636090.	TAS	Process
GO:0033592	RNA strand annealing activity	27546789.	IDA	Function
GO:0034063	stress granule assembly	21883093.	IDA	Process
GO:0034774	secretory granule lumen	-	TAS	Component
GO:0035556	intracellular signal transduction	18636090.	IDA	Process
GO:0035613	RNA stem-loop binding	22872150.	IDA	Function
GO:0042256	mature ribosome assembly	22323517.	IMP	Process
GO:0043024	ribosomal small subunit binding	22323517.	IDA	Function
GO:0043065	positive regulation of apoptotic process	16301996.	IMP	Process
GO:0043066	negative regulation of apoptotic process	18846110.	IMP	Process
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	18846110.	IMP	Process
GO:0043273	CTPase activity	10074132.	IDA	Function
GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	16301996.	IMP	Process
GO:0043312	neutrophil degranulation	-	TAS	Process
GO:0043539	protein serine/threonine kinase activator activity	23413191.	IDA	Function
GO:0045070	positive regulation of viral genome replication	20862261.	IMP	Process
GO:0045087	innate immune response	18583960.	IMP	Process
GO:0045296	cadherin binding	25468996.	HDA	Function
GO:0045727	positive regulation of translation	18596238.22872150.	IDA	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	16818630.18636090.	IDA	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	18583960.	IMP	Process
GO:0045948	positive regulation of translational initiation	20837705.	IMP	Process
GO:0048027	mRNA 5'-UTR binding	22872150.	IDA	Function
GO:0070062	extracellular exosome	19056867.19199708.20458337.	HDA	Component
GO:0071243	cellular response to arsenic-containing substance	21883093.	IDA	Process
GO:0071470	cellular response to osmotic stress	21883093.	IDA	Process
GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production	18583960.	TAS	Process
GO:0071902	positive regulation of protein serine/threonine kinase activity	23413191.	IDA	Process
GO:0090263	positive regulation of canonical Wnt signaling pathway	23413191.	IMP	Process
GO:0097193	intrinsic apoptotic signaling pathway	16301996.	IMP	Process
GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	20837705.	IMP	Process
GO:1903608	protein localization to cytoplasmic stress granule	24965446.	IMP	Process
GO:1904813	ficolin-1-rich granule lumen	-	TAS	Component
GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	21883093.	IMP	Process

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

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Pathway

PPI

Paralog

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Gene Ontology

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Cell lines and drugs in GSE70138 or GSE92742

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