EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
22240482	RACK1 suppresses gastric tumorigenesis by stabilizing the β-catenin destruction complex.	Gastroenterology	2012 Apr	Deng YZ	doi: 10.1053/j.gastro.2011.12.046
24481459	Silencing the receptor of activated C-kinase 1 (RACK1) suppresses tumorigenicity in epithelial ovarian cancer in vitro and in vivo.	Int J Oncol	2014 Apr	Lin Y	doi: 10.3892/ijo.2014.2274
21848913	Downregulation of receptor for activated C-kinase 1 (RACK1) suppresses tumor growth by inhibiting tumor cell proliferation and tumor-associated angiogenesis.	Cancer Sci	2011 Nov	Wang F	doi: 10.1111/j.1349-7006.2011.02065.x
19892429	Expression of RACK1 is a novel biomarker in pulmonary adenocarcinomas.	Lung Cancer	2010 Jul	Nagashio R	doi: 10.1016/j.lungcan.2009.09.015
26199092	Loss of RACK1 Promotes Metastasis of Gastric Cancer by Inducing a miR-302c/IL8 Signaling Loop.	Cancer Res	2015 Sep 15	Chen L	doi: 10.1158/0008-5472.CAN-14-3690
15548575	Age-related decline in RACK-1 expression in human leukocytes is correlated to plasma levels of dehydroepiandrosterone.	J Leukoc Biol	2005 Feb	Corsini E	-
27453417	Receptor for activated protein kinase C 1 suppresses gastric tumor progression through nuclear factor-kB pathway.	Indian J Cancer	2015 Dec	Yong-Zheng X	doi: 10.4103/0019-509X.186572.
26893362	RACK1 overexpression is linked to acquired imatinib resistance in gastrointestinal stromal tumor.	Oncotarget	2016 Mar 22	Gao X	doi: 10.18632/oncotarget.7426.
25686824	RACK1 is a candidate gene associated with the prognosis of patients with early stage non-small cell lung cancer.	Oncotarget	2015 Feb 28	Choi YY	-
18420585	RACK1 and CIS mediate the degradation of BimEL in cancer cells.	J Biol Chem	2008 Jun 13	Zhang W	doi: 10.1074/jbc.M802360200
25065497	Ion channel TRPM8 promotes hypoxic growth of prostate cancer cells via an O2 -independent and RACK1-mediated mechanism of HIF-1α stabilization.	J Pathol	2014 Dec	Yu S	doi: 10.1002/path.4413
20020495	RACK1: A superior independent predictor for poor clinical outcome in breast cancer.	Int J Cancer	2010 Sep 1	Cao XX	doi: 10.1002/ijc.25120.
22314363	EphB3 suppresses non-small-cell lung cancer metastasis via a PP2A/RACK1/Akt signalling complex.	Nat Commun	2012 Feb 7	Li G	doi: 10.1038/ncomms1675.
23912224	RACK1 promotes prostate cancer cell proliferation, invasion and metastasis.	Mol Med Rep	2013 Oct	Shen F	doi: 10.3892/mmr.2013.1612
28760343	RACK1 promotes radiation resistance in esophageal cancer via regulating AKT pathway and Bcl-2 expression.	Biochem Biophys Res Commun	2017 Sep 23	Liu B	doi: 10.1016/j.bbrc.2017.07.153
28418088	RACK1 forms a complex with FGFR1 and PKM2, and stimulates the growth and migration of squamous lung cancer cells.	Mol Carcinog	2017 Nov	Zhou C	doi: 10.1002/mc.22663
28797110	GNB2L1 and its O-GlcNAcylation regulates metastasis via modulating epithelial-mesenchymal transition in the chemoresistance of gastric cancer.	PLoS One	2017 Aug 10	Cheng S	doi: 10.1371/journal.pone.0182696
26863570	Long noncoding RNA OR3A4 promotes metastasis and tumorigenicity in gastric cancer.	Oncotarget	2016 May 24	Guo X	doi: 10.18632/oncotarget.7217.
27600565	RACK1 stabilises the activity of PP2A to regulate the transformed phenotype in mammary epithelial cells.	Cell Signal	2017 Jul	Kiely M	doi: 10.1016/j.cellsig.2016.09.001
29048616	The receptor for activated protein kinase C promotes cell growth, invasion and migration in cervical cancer.	Int J Oncol	2017 Nov	Liao S	doi: 10.3892/ijo.2017.4137

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr5	181238127	Missense_Mutation	novel	A250G	0.5
BLCA	chr5	181239172	Nonsense_Mutation	novel	W177*	0.49
BLCA	chr5	181241651	Intron	novel		0.44
BLCA	chr5	181241545	Missense_Mutation	novel	D126H	0.15
BRCA	chr5	181239273	Intron	novel		0.12
BRCA	chr5	181238277	Intron	novel		0.1
BRCA	chr5	181242320	Silent	novel	L45L	0.1
BRCA	chr5	181243769	Missense_Mutation	novel	L11P	0.04
BRCA	chr5	181238141	Silent	NA	R245R	0.18
BRCA	chr5	181237008	Missense_Mutation	novel	R308P	0.05
BRCA	chr5	181237279	Intron	NA		0.17
BRCA	chr5	181238243	Splice_Region	novel		0.17
BRCA	chr5	181239078	Missense_Mutation	novel	S209A	0.1
BRCA	chr5	181243822	5'UTR	novel		0.15
BRCA	chr5	181241718	Intron	novel		0.29
BRCA	chr5	181239297	Intron	novel		0.21
BRCA	chr5	181239577	Silent	NA	E145E	0.22
BRCA	chr5	181242195	Missense_Mutation	NA	L87R	0.25
BRCA	chr5	181239282	Intron	novel		0.25
BRCA	chr5	181241564	Missense_Mutation	NA	Q119H	0.24
BRCA	chr5	181238834	Intron	novel		0.48
CESC	chr5	181242193	Missense_Mutation	novel	R88C	0.11
CESC	chr5	181242216	Nonsense_Mutation	novel	S80*	0.05
CESC	chr5	181238263	Intron	novel		0.08
CESC	chr5	181243716	Missense_Mutation	novel	D29H	0.14
COAD	chr5	181237117	Intron	novel		0.19
COAD	chr5	181239000	Intron	novel		0.55
COAD	chr5	181239218	Intron	novel		0.05
COAD	chr5	181241573	Silent	NA	D116D	0.31
COAD	chr5	181239385	Intron	novel		0.42
COAD	chr5	181242175	Missense_Mutation	novel	T94A	0.4
COAD	chr5	181241722	Intron	novel		0.45
COAD	chr5	181239252	Intron	novel		0.08
COAD	chr5	181241638	Missense_Mutation	NA	G95S	0.38
COAD	chr5	181239517	Silent	rs139942873	I165I	0.35
ESCA	chr5	181242293	Missense_Mutation	novel	I54M	0.57
GBM	chr5	181243763	Missense_Mutation	novel	G13D	0.56
GBM	chr5	181239120	Missense_Mutation	novel	L195M	0.14
GBM	chr5	181241776	Intron	novel		0.16
GBM	chr5	181242000	Intron	novel		0.14
HNSC	chr5	181239087	Missense_Mutation	NA	L206F	0.51
HNSC	chr5	181238348	Intron	novel		0.19
HNSC	chr5	181239085	Silent	novel	L206L	0.05
HNSC	chr5	181241683	Intron	novel		0.07
HNSC	chr5	181238325	Intron	novel		0.16
HNSC	chr5	181238329	Intron	novel		0.63
HNSC	chr5	181241724	Intron	novel		0.07
KIRC	chr5	181243812	5'UTR	novel		0.33
KIRP	chr5	181242131	Intron	novel		0.3
KIRP	chr5	181243768	Silent	novel	L11L	0.28
KIRP	chr5	181243822	5'UTR	novel		0.25
LAML	chr5	181238328	Intron	novel		0.07
LGG	chr5	181238164	Missense_Mutation	NA	A238T	0.09
LGG	chr5	181241728	Intron	novel		0.16
LGG	chr5	181242308	Missense_Mutation	novel	E49D	0.13
LIHC	chr5	181239567	Missense_Mutation	rs768541673	E149Q	0.46
LIHC	chr5	181239153	Missense_Mutation	novel	L184M	0.09
LIHC	chr5	181238320	Intron	novel		0.48
LIHC	chr5	181241673	Intron	novel		0.38
LIHC	chr5	181237157	Intron	novel		0.42
LUAD	chr5	181238099	Nonsense_Mutation	novel	W259*	0.12
LUAD	chr5	181241575	Missense_Mutation	novel	D116N	0.1
LUAD	chr5	181243768	Silent	novel	L11L	0.16
LUAD	chr5	181239449	Intron	novel		0.79
LUAD	chr5	181241496	Missense_Mutation	NA	V142A	0.39
LUSC	chr5	181241580	Missense_Mutation	novel	S114F	0.31
LUSC	chr5	181241594	Silent	NA	L109L	0.26
LUSC	chr5	181239034	Intron	novel		0.17
LUSC	chr5	181242341	Missense_Mutation	novel	K38N	0.33
LUSC	chr5	181241995	Intron	novel		0.1
OV	chr5	181241542	Missense_Mutation	novel	K127Q	0.06
OV	chr5	181241617	Missense_Mutation	novel	V102L	0.08
OV	chr5	181241582	Frame_Shift_Ins	novel	*F113Lfs73**	0.15
OV	chr5	181239296	Intron	novel		0.11
PAAD	chr5	181236937	3'UTR	novel		0.18
PRAD	chr5	181239064	Splice_Region	novel		0.1
SARC	chr5	181243201	Intron	novel		0.08
SARC	chr5	181237689	Silent	novel	L270L	0.13
SKCM	chr5	181237711	Silent	novel	E262E	0.43
SKCM	chr5	181239403	Intron	novel		0.44
SKCM	chr5	181241528	Silent	novel	L131L	0.4
SKCM	chr5	181241648	Intron	novel		0.21
SKCM	chr5	181241594	Silent	NA	L109L	0.28
SKCM	chr5	181241818	Intron	novel		0.16
SKCM	chr5	181238212	Missense_Mutation	NA	N222D	0.49
SKCM	chr5	181241622	Missense_Mutation	NA	R100L	0.42
SKCM	chr5	181238143	Missense_Mutation	NA	R245C	0.46
STAD	chr5	181237713	Missense_Mutation	NA	E262Q	0.16
STAD	chr5	181237659	Missense_Mutation	NA	K280E	0.36
STAD	chr5	181238164	Missense_Mutation	NA	A238T	0.05
STAD	chr5	181238900	Intron	novel		0.42
STAD	chr5	181237118	Intron	NA		0.22
STAD	chr5	181241824	Intron	novel		0.46
STAD	chr5	181239109	Silent	NA	V198V	0.19
STAD	chr5	181237118	Intron	NA		0.53
THCA	chr5	181241683	Intron	novel		0.08
THCA	chr5	181241684	Intron	novel		0.17
THCA	chr5	181241684	Intron	novel		0.08
THCA	chr5	181241685	Intron	novel		0.08
THCA	chr5	181241684	Intron	novel		0.09
THCA	chr5	181241685	Intron	novel		0.09
UCEC	chr5	181239195	Intron	novel		0.49
UCEC	chr5	181239574	Missense_Mutation	NA	S146R	0.35
UCEC	chr5	181238209	Missense_Mutation	novel	E223K	0.06
UCEC	chr5	181241934	Intron	novel		0.25
UCEC	chr5	181241526	Missense_Mutation	novel	W132L	0.25
UCEC	chr5	181239248	Intron	novel		0.48
UCEC	chr5	181243735	Silent	novel	A22A	0.43
UCEC	chr5	181242331	Missense_Mutation	novel	M42V	0.24
UCEC	chr5	181239481	Splice_Region	novel		0.44
UCEC	chr5	181241725	Intron	novel		0.41
UCEC	chr5	181241888	Intron	novel		0.39
UCEC	chr5	181237117	Intron	novel		0.29
UCEC	chr5	181241686	Intron	novel		0.23
UCEC	chr5	181242337	Missense_Mutation	novel	I40V	0.17
UCEC	chr5	181239296	Intron	novel		0.33
UCEC	chr5	181239393	Intron	novel		0.36
UCEC	chr5	181239194	Intron	novel		0.51
UCEC	chr5	181241718	Intron	novel		0.29
UCEC	chr5	181238102	Silent	NA	I258I	0.32
UCEC	chr5	181241813	Intron	novel		0.12
UCEC	chr5	181242193	Missense_Mutation	novel	R88C	0.38
UCEC	chr5	181241931	Intron	novel		0.43
UCEC	chr5	181237686	Missense_Mutation	novel	K271E	0.49
UCEC	chr5	181237234	Intron	novel		0.18
UCEC	chr5	181238883	Intron	novel		0.42
UCEC	chr5	181237619	Missense_Mutation	novel	A293D	0.62
UCEC	chr5	181239165	Missense_Mutation	novel	A180T	0.54
UCEC	chr5	181239044	Intron	novel		0.43
UCEC	chr5	181239112	Silent	rs754736780	T197T	0.31
UCEC	chr5	181241623	Nonsense_Mutation	novel	R100*	0.41
UCEC	chr5	181238349	Intron	novel		0.58

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRP	AMP	0.1146	0.069756
KIRP	DEL	0.0313	0.11554
LUAD	AMP	0.1764	0.24967
LUSC	DEL	0.5868	0.002071
MESO	DEL	0.1149	0.20184
PRAD	AMP	0.0305	0.16448
SKCM	AMP	0.1253	0.23703
THCA	DEL	0	0.23456

Survival Analysis

Cancer	P-value	Q-value
MESO	0.047	Kaplan-Meier Survival Analysis
ACC	0.016	Kaplan-Meier Survival Analysis
UCS	0.021	Kaplan-Meier Survival Analysis
KIRP	0.0044	Kaplan-Meier Survival Analysis
GBM	0.0092	Kaplan-Meier Survival Analysis
LIHC	0.00065	Kaplan-Meier Survival Analysis
LGG	0.00087	Kaplan-Meier Survival Analysis
UVM	0.022	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000204628 (Gene tree)
Gene ID: 10399
Gene Symbol: RACK1
Alias: Gnb2-rs1|H12.3|GNB2L1
Full Name: receptor for activated C kinase 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 11,188 bases
Position: chr5:181,236,909-181,248,096
Accession: 4399
RBP type: non-canonical RBP
Summary: (Receptor For Activated C Kinase 1) is a Protein Coding gene. Diseases associated with RACK1 include Wells Syndrome. Among its related pathways are TNF signaling (REACTOME) and Regulation of CFTR activity (norm and CF).

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
21771594	Evidence for the association of the human regulatory protein Ki-1/57 with the translational machinery.	FEBS Lett	2011 Aug 19	Goncalves Kde A	doi: 10.1016/j.febslet.2011.07.010
22123745	The eIF3c/NIP1 PCI domain interacts with RNA and RACK1/ASC1 and promotes assembly of translation preinitiation complexes.	Nucleic Acids Res	2012 Mar	Kouba T	doi: 10.1093/nar/gkr1083
28267599	The RNA-binding protein SERBP1 interacts selectively with the signaling protein RACK1.	Cell Signal	2017 Jul	Bolger GB	doi: 10.1016/j.cellsig.2017.03.001
18954305	Structural basis and specificity of human otubain 1-mediated deubiquitination.	Biochem J	2009 Mar 1	Edelmann MJ	doi: 10.1042/BJ20081318.
18816594	mrtl-A translation/localization regulatory protein encoded within the human c-myc locus and distributed throughout the endoplasmic and nucleoplasmic reticular network.	J Cell Biochem	2008 Nov 1	Choi H	doi: 10.1002/jcb.21909.
23379559	Proteins of the human 40S ribosomal subunit involved in hepatitis C IRES binding as revealed from fluorescent labeling.	Biochemistry (Mosc)	2013 Jan	Malygin AA	doi: 10.1134/S0006297913010069.
20871634	Regulation of receptor for activated C kinase 1 protein by the von Hippel-Lindau tumor suppressor in IGF-I-induced renal carcinoma cell invasiveness.	Oncogene	2011 Feb 3	He X	doi: 10.1038/onc.2010.427
24852294	Integrative functional genomics of hepatitis C virus infection identifies host dependencies in complete viral replication cycle.	PLoS Pathog	2014 May 22	Li Q	doi: 10.1371/journal.ppat.1004163
26644407	LARP4 Is Regulated by Tumor Necrosis Factor Alpha in a Tristetraprolin-Dependent Manner.	Mol Cell Biol	2015 Dec 7	Mattijssen S	doi: 10.1128/MCB.00804-15

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000509148	RACK1-221	888	-	ENSP00000424654	83 (aa)	-	H0Y9P0
ENST00000507261	RACK1-215	590	-	-	- (aa)	-	-
ENST00000507000	RACK1-214	685	-	ENSP00000421416	194 (aa)	-	D6RFX4
ENST00000510199	RACK1-223	1100	-	ENSP00000423569	300 (aa)	-	D6R9L0
ENST00000504325	RACK1-210	1098	-	ENSP00000422198	116 (aa)	-	D6R909
ENST00000503170	RACK1-207	461	-	-	- (aa)	-	-
ENST00000514455	RACK1-233	791	-	ENSP00000426708	101 (aa)	-	D6RF23
ENST00000507756	RACK1-217	889	-	ENSP00000422316	274 (aa)	-	H0Y8W2
ENST00000376817	RACK1-201	965	-	ENSP00000366013	273 (aa)	-	J3KPE3
ENST00000502890	RACK1-204	705	-	-	- (aa)	-	-
ENST00000515417	RACK1-234	873	-	-	- (aa)	-	-
ENST00000502548	RACK1-202	1090	-	-	- (aa)	-	-
ENST00000506312	RACK1-213	559	-	ENSP00000426270	71 (aa)	-	D6RGK8
ENST00000512805	RACK1-227	1403	-	ENSP00000426909	317 (aa)	-	P63244
ENST00000504726	RACK1-211	388	-	ENSP00000426046	86 (aa)	-	D6RHJ5
ENST00000511473	RACK1-224	1150	-	ENSP00000420936	39 (aa)	-	D6RDI0
ENST00000507273	RACK1-216	358	-	-	- (aa)	-	-
ENST00000502844	RACK1-203	1460	-	ENSP00000422029	236 (aa)	-	D6R9Z1
ENST00000508682	RACK1-219	1208	-	ENSP00000424760	147 (aa)	-	D6RAU2
ENST00000626067	RACK1-235	564	-	ENSP00000486170	153 (aa)	-	E9PD14
ENST00000512968	RACK1-228	1058	-	ENSP00000425008	321 (aa)	-	D6REE5
ENST00000502905	RACK1-205	643	-	ENSP00000426960	198 (aa)	-	H0YAF8
ENST00000513027	RACK1-229	697	-	ENSP00000421356	197 (aa)	-	D6RFZ9
ENST00000513060	RACK1-230	1651	-	-	- (aa)	-	-
ENST00000511900	RACK1-226	922	-	ENSP00000422768	269 (aa)	-	D6RAC2
ENST00000504128	RACK1-209	990	-	ENSP00000427677	247 (aa)	-	H0YAM7
ENST00000503081	RACK1-206	587	-	ENSP00000424237	160 (aa)	-	D6RBD0
ENST00000508044	RACK1-218	554	-	-	- (aa)	-	-
ENST00000514183	RACK1-231	1439	-	-	- (aa)	-	-
ENST00000505461	RACK1-212	1005	-	-	- (aa)	-	-
ENST00000503494	RACK1-208	843	-	ENSP00000426111	153 (aa)	-	E9PD14
ENST00000508963	RACK1-220	581	-	-	- (aa)	-	-
ENST00000509535	RACK1-222	456	-	ENSP00000421838	138 (aa)	-	H0Y8R5
ENST00000511566	RACK1-225	825	-	ENSP00000426101	233 (aa)	-	D6RHH4
ENST00000514318	RACK1-232	581	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000204628's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa05162	Measles	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000204628's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000204628	RACK1	97	78.723	WBGene00010556	rack-1	98	72.188	Caenorhabditis_elegans
ENSG00000204628	RACK1	100	79.487	FBgn0020618	Rack1	99	79.812	Drosophila_melanogaster
ENSG00000204628	RACK1	100	100.000	ENSMUSG00000020372	Rack1	100	100.000	Mus_musculus
ENSG00000204628	RACK1	97	66.667	YMR116C	ASC1	97	53.822	Saccharomyces_cerevisiae

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001891	phagocytic cup	21347310.	IDA	Component
GO:0001934	positive regulation of protein phosphorylation	21873635.	IBA	Process
GO:0001934	positive regulation of protein phosphorylation	11312657.17108144.	IDA	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005080	protein kinase C binding	21873635.	IBA	Function
GO:0005080	protein kinase C binding	11279199.	IDA	Function
GO:0005102	signaling receptor binding	12809483.	NAS	Function
GO:0005515	protein binding	10849009.11046044.11279199.11312657.12809483.14500341.17108144.18194455.18420585.18816594.18954305.19674157.19785988.20010870.20080539.20103773.20541605.20871634.21098120.21146485.21347310.21525958.21750715.21988832.22210188.23866081.24947010.25910212.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	10849009.17108144.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005737	cytoplasm	10849009.19785988.	IDA	Component
GO:0005739	mitochondrion	19767770.	IMP	Component
GO:0005829	cytosol	21873635.	IBA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	19767770.	IMP	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006915	apoptotic process	-	IEA	Process
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	19767770.	IMP	Process
GO:0007049	cell cycle	-	IEA	Process
GO:0007369	gastrulation	-	IEA	Process
GO:0008200	ion channel inhibitor activity	-	ISS	Function
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	19767770.	IMP	Function
GO:0010629	negative regulation of gene expression	19451233.	IMP	Process
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	-	TAS	Process
GO:0015935	small ribosomal subunit	-	ISS	Component
GO:0016032	viral process	-	IEA	Process
GO:0016567	protein ubiquitination	28132843.	IMP	Process
GO:0017148	negative regulation of translation	-	ISS	Process
GO:0019899	enzyme binding	21873635.	IBA	Function
GO:0019899	enzyme binding	20819076.	IPI	Function
GO:0019903	protein phosphatase binding	11278757.	IPI	Function
GO:0022627	cytosolic small ribosomal subunit	21873635.	IBA	Component
GO:0030178	negative regulation of Wnt signaling pathway	-	ISS	Process
GO:0030292	protein tyrosine kinase inhibitor activity	9584165.	IDA	Function
GO:0030308	negative regulation of cell growth	9584165.	IDA	Process
GO:0030332	cyclin binding	15159402.	IPI	Function
GO:0030335	positive regulation of cell migration	20499158.	IDA	Process
GO:0030425	dendrite	-	ISS	Component
GO:0030496	midbody	15166316.	IDA	Component
GO:0030971	receptor tyrosine kinase binding	9584165.	IDA	Function
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	19785988.	IDA	Process
GO:0032464	positive regulation of protein homooligomerization	20541605.	IDA	Process
GO:0032464	positive regulation of protein homooligomerization	19767770.	IMP	Process
GO:0032880	regulation of protein localization	-	ISS	Process
GO:0033137	negative regulation of peptidyl-serine phosphorylation	20103773.	IMP	Process
GO:0035591	signaling adaptor activity	20103773.	IMP	Function
GO:0042169	SH2 domain binding	9584165.11279199.	IDA	Function
GO:0042803	protein homodimerization activity	24947010.	IDA	Function
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	19674157.	IMP	Process
GO:0043022	ribosome binding	21873635.	IBA	Function
GO:0043022	ribosome binding	28132843.	IDA	Function
GO:0043025	neuronal cell body	-	ISS	Component
GO:0043065	positive regulation of apoptotic process	20541605.	IDA	Process
GO:0043065	positive regulation of apoptotic process	19767770.	IMP	Process
GO:0043204	perikaryon	-	IEA	Component
GO:0043473	pigmentation	-	IEA	Process
GO:0043547	positive regulation of GTPase activity	20499158.	IDA	Process
GO:0045296	cadherin binding	25468996.	HDA	Function
GO:0048471	perinuclear region of cytoplasm	11279199.	IDA	Component
GO:0048511	rhythmic process	-	IEA	Process
GO:0050765	negative regulation of phagocytosis	21347310.	IMP	Process
GO:0051302	regulation of cell division	-	ISS	Process
GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity	20819076.	IMP	Process
GO:0051726	regulation of cell cycle	9584165.	IDA	Process
GO:0051898	negative regulation of protein kinase B signaling	19767770.	IMP	Process
GO:0051901	positive regulation of mitochondrial depolarization	19767770.	IMP	Process
GO:0060090	molecular adaptor activity	20819076.	TAS	Function
GO:0061099	negative regulation of protein tyrosine kinase activity	-	IEA	Process
GO:0070062	extracellular exosome	19056867.	HDA	Component
GO:0071333	cellular response to glucose stimulus	20103773.	IDA	Process
GO:0071363	cellular response to growth factor stimulus	20010870.	IDA	Process
GO:0072344	rescue of stalled ribosome	21873635.	IBA	Process
GO:0072344	rescue of stalled ribosome	28132843.	IMP	Process
GO:1900102	negative regulation of endoplasmic reticulum unfolded protein response	22013210.	TAS	Process
GO:1903208	negative regulation of hydrogen peroxide-induced neuron death	24947010.	IGI	Process
GO:1990630	IRE1-RACK1-PP2A complex	20103773.	IDA	Component
GO:2000114	regulation of establishment of cell polarity	-	ISS	Process
GO:2000304	positive regulation of ceramide biosynthetic process	-	TAS	Process
GO:2000543	positive regulation of gastrulation	-	ISS	Process
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	19767770.	IMP	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.