EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr14	24186969	Missense_Mutation	novel	C222Y	0.2
BLCA	chr14	24184046	Missense_Mutation	novel	Q607H	0.06
BLCA	chr14	24188495	Intron	novel		0.42
BLCA	chr14	24182324	Missense_Mutation	novel	F851S	0.09
BLCA	chr14	24188568	Missense_Mutation	rs751437225	S47L	0.19	IBN_N
BLCA	chr14	24181807	Silent	novel	L948L	0.32
BLCA	chr14	24183795	Nonsense_Mutation	novel	S658*	0.12
BLCA	chr14	24186200	Intron	novel		0.26
BLCA	chr14	24187764	Nonsense_Mutation	NA	S104*	0.34
BLCA	chr14	24183832	Missense_Mutation	novel	E646K	0.62
BRCA	chr14	24183018	Silent	rs763537508	L793L	0.12
BRCA	chr14	24187764	Missense_Mutation	NA	S104L	0.29
BRCA	chr14	24182409	Splice_Region	novel		0.15
BRCA	chr14	24182067	Missense_Mutation	novel	R899G	0.11
BRCA	chr14	24182159	Missense_Mutation	NA	Q868R	0.46
BRCA	chr14	24182053	Silent	novel	V903V	0.15
BRCA	chr14	24183141	Silent	NA	V752V	0.26
CESC	chr14	24184353	Nonsense_Mutation	NA	Q568*	0.47
CESC	chr14	24185470	Missense_Mutation	novel	E423K	0.28
CESC	chr14	24187480	Missense_Mutation	rs760564068	E170K	0.26
CESC	chr14	24187682	Frame_Shift_Del	novel	*H131Qfs12**	0.07
CESC	chr14	24181528	Missense_Mutation	novel	Q1010H	0.56
CESC	chr14	24180448	Silent	novel	L1080L	0.31
CESC	chr14	24187515	Missense_Mutation	rs780660470	R158Q	0.27
CESC	chr14	24183059	Missense_Mutation	rs201767926	R780C	0.26
CESC	chr14	24181715	Missense_Mutation	rs778843210	P979L	0.27
CESC	chr14	24181744	Missense_Mutation	rs769441387	L969F	0.1
COAD	chr14	24180726	Silent	novel	I1026I	0.38
COAD	chr14	24186950	Missense_Mutation	NA	L228F	0.35
COAD	chr14	24188622	Missense_Mutation	novel	Q29P	0.23	IBN_N
COAD	chr14	24186763	Missense_Mutation	rs369050610	A262V	0.25
COAD	chr14	24184373	Missense_Mutation	rs769903817	P561L	0.25
COAD	chr14	24187484	Silent	novel	L168L	0.33
COAD	chr14	24183860	Silent	rs184433827	D636D	0.44
COAD	chr14	24181550	Missense_Mutation	rs369101802	R1003H	0.31
COAD	chr14	24185963	Missense_Mutation	novel	M356T	0.07
COAD	chr14	24183348	Missense_Mutation	NA	H710R	0.33
COAD	chr14	24183615	Missense_Mutation	rs369678433	V680M	0.29
COAD	chr14	24188692	Intron	novel		0.08
COAD	chr14	24184018	Missense_Mutation	rs755630919	R617C	0.24
COAD	chr14	24187114	Missense_Mutation	NA	A209T	0.27
COAD	chr14	24184406	Missense_Mutation	novel	V550G	0.32
COAD	chr14	24188830	5'UTR	novel		0.33
DLBC	chr14	24182101	Silent	novel	Q887Q	0.25
DLBC	chr14	24182071	Silent	novel	V897V	0.15
ESCA	chr14	24188733	Nonsense_Mutation	novel	E19*	0.07
ESCA	chr14	24184883	Silent	rs749101940	S502S	0.46
GBM	chr14	24187144	Missense_Mutation	rs757118268	A199T	0.56
GBM	chr14	24186927	Missense_Mutation	novel	V236E	0.51
GBM	chr14	24188421	Splice_Region	novel	I53I	0.53
GBM	chr14	24181778	Frame_Shift_Del	novel	*R958Lfs12**	0.13
GBM	chr14	24187708	Missense_Mutation	novel	L123V	0.11
GBM	chr14	24186878	Missense_Mutation	novel	E252D	0.42
HNSC	chr14	24180448	Silent	novel	L1080L	0.41
HNSC	chr14	24181594	Silent	novel	A988A	0.13
HNSC	chr14	24187120	Missense_Mutation	novel	I207F	0.08
HNSC	chr14	24181768	Silent	novel	I961I	0.15
HNSC	chr14	24183616	Silent	novel	A679A	0.19
HNSC	chr14	24184654	Silent	novel	S544S	0.58
KIRC	chr14	24186781	Missense_Mutation	NA	N256T	0.34
KIRC	chr14	24188219	Missense_Mutation	rs778689897	T92R	0.52
KIRC	chr14	24181958	Missense_Mutation	NA	Q935P	0.25
KIRP	chr14	24185473	Missense_Mutation	NA	S422T	0.43
KIRP	chr14	24182341	Silent	novel	A845A	0.26
KIRP	chr14	24184760	Missense_Mutation	rs768075624	T509M	0.32
KIRP	chr14	24186884	Nonsense_Mutation	novel	C250*	0.27
LAML	chr14	24185484	Frame_Shift_Ins	novel	*L418Pfs118**	0.08
LGG	chr14	24186716	Missense_Mutation	novel	K278E	0.51
LGG	chr14	24187768	Missense_Mutation	novel	L103F	0.35
LGG	chr14	24182374	Silent	rs767137886	H834H	0.35
LIHC	chr14	24185268	Silent	rs369559477	L441L	0.4
LIHC	chr14	24180480	Missense_Mutation	novel	K1070Q	0.21
LIHC	chr14	24183997	Splice_Site	novel	X623_splice	0.38
LIHC	chr14	24188399	Missense_Mutation	NA	T61A	0.38	IBN_N
LIHC	chr14	24185536	Frame_Shift_Ins	novel	*K401Vfs2**	0.49
LIHC	chr14	24185537	Silent	NA	C400C	0.49
LUAD	chr14	24183002	Missense_Mutation	rs747787561	V799M	0.19
LUAD	chr14	24183615	Missense_Mutation	rs369678433	V680M	0.47
LUAD	chr14	24187705	Nonsense_Mutation	NA	Q124*	0.31
LUAD	chr14	24183661	Missense_Mutation	novel	S664R	0.09
LUAD	chr14	24187728	Missense_Mutation	NA	W116L	0.21
LUAD	chr14	24183876	Missense_Mutation	novel	S631C	0.27
LUAD	chr14	24185926	Silent	rs769264789	Q368Q	0.12
LUSC	chr14	24187799	Splice_Region	novel		0.16
LUSC	chr14	24187094	Silent	NA	P215P	0.23
LUSC	chr14	24185221	Missense_Mutation	novel	K457R	0.31
LUSC	chr14	24185874	Missense_Mutation	NA	H386D	0.35
LUSC	chr14	24184388	Missense_Mutation	novel	G556A	0.21
OV	chr14	24187551	Missense_Mutation	novel	V146E	0.23
OV	chr14	24187436	Silent	novel	L184L	0.13
OV	chr14	24187683	Missense_Mutation	novel	H131L	0.11
OV	chr14	24183063	Frame_Shift_Del	novel	*V778Sfs9**	0.14
PAAD	chr14	24181794	Nonsense_Mutation	rs535037141	R953*	0.21
PAAD	chr14	24183143	Missense_Mutation	rs372694223	V752M	0.15
PRAD	chr14	24182016	Nonsense_Mutation	rs767458231	R916*	0.23
SARC	chr14	24184061	Silent	rs371519200	A602A	0.57
SARC	chr14	24185878	Silent	rs752936115	G384G	0.52
SARC	chr14	24183881	Silent	novel	S629S	0.21
SKCM	chr14	24186409	Missense_Mutation	novel	L295F	0.18
SKCM	chr14	24186410	Silent	novel	T294T	0.17
SKCM	chr14	24186362	Silent	rs778239058	P310P	0.21
SKCM	chr14	24184736	Missense_Mutation	NA	P517L	0.34
SKCM	chr14	24185563	Silent	NA	L392L	0.31
SKCM	chr14	24184320	Missense_Mutation	rs370556515	D579N	0.36
SKCM	chr14	24184961	Silent	NA	Y476Y	0.25
SKCM	chr14	24186943	Missense_Mutation	NA	L231V	0.46
SKCM	chr14	24181715	Missense_Mutation	rs778843210	P979L	0.32
SKCM	chr14	24185911	Silent	novel	L373L	0.29
SKCM	chr14	24183054	Silent	novel	S781S	0.23
SKCM	chr14	24187449	Missense_Mutation	novel	S180F	0.35
SKCM	chr14	24186451	Missense_Mutation	novel	A281T	0.23
SKCM	chr14	24186452	Splice_Site	novel	X281_splice	0.24
SKCM	chr14	24187096	Missense_Mutation	NA	P215S	0.42
SKCM	chr14	24181752	Missense_Mutation	novel	R967C	0.15
SKCM	chr14	24185232	Silent	NA	H453H	0.33
SKCM	chr14	24187095	Missense_Mutation	novel	P215L	0.44
SKCM	chr14	24187096	Missense_Mutation	NA	P215S	0.44
SKCM	chr14	24183030	Silent	NA	P789P	0.3
SKCM	chr14	24183616	Silent	novel	A679A	0.19
SKCM	chr14	24183617	Missense_Mutation	novel	A679V	0.19
SKCM	chr14	24186404	Silent	NA	F296F	0.46
SKCM	chr14	24186751	Missense_Mutation	rs754574474	R266H	0.3
SKCM	chr14	24181809	Missense_Mutation	NA	L948F	0.3
SKCM	chr14	24184360	Missense_Mutation	novel	E565D	0.57
SKCM	chr14	24184678	Silent	NA	D536D	0.6
STAD	chr14	24187666	Frame_Shift_Ins	novel	*M137Rfs7**	0.27
STAD	chr14	24182313	Missense_Mutation	NA	F855V	0.13
STAD	chr14	24183028	Frame_Shift_Del	NA	*P790Lfs116**	0.17
STAD	chr14	24186150	Frame_Shift_Del	novel	*E347Rfs7**	0.24
STAD	chr14	24187677	Missense_Mutation	NA	P133L	0.28
STAD	chr14	24183640	Silent	NA	D671D	0.46
STAD	chr14	24183152	Missense_Mutation	novel	A749T	0.06
STAD	chr14	24187687	Missense_Mutation	rs541325634	P130S	0.44
STAD	chr14	24181779	Missense_Mutation	rs571236753	R958C	0.29
STAD	chr14	24184903	Missense_Mutation	novel	A496T	0.28
STAD	chr14	24188629	Missense_Mutation	NA	Q27K	0.19	IBN_N
STAD	chr14	24185483	Silent	NA	L418L	0.16
STAD	chr14	24187537	Missense_Mutation	rs749422296	E151K	0.16
THCA	chr14	24188475	Intron	novel		0.26
UCEC	chr14	24183320	Missense_Mutation	NA	E719D	0.55
UCEC	chr14	24185925	Missense_Mutation	rs747819166	R369C	0.28
UCEC	chr14	24187552	Missense_Mutation	novel	V146L	0.32
UCEC	chr14	24180561	Missense_Mutation	rs566385618	A1043T	0.17
UCEC	chr14	24185313	Splice_Site	novel	X427_splice	0.18
UCEC	chr14	24182115	Missense_Mutation	novel	A883T	0.1
UCEC	chr14	24182303	Missense_Mutation	novel	F858S	0.41
UCEC	chr14	24188441	Intron	novel		0.35
UCEC	chr14	24180520	Silent	rs777326997	T1056T	0.43
UCEC	chr14	24183466	Missense_Mutation	novel	K704R	0.06
UCEC	chr14	24187536	Missense_Mutation	novel	E151G	0.31
UCEC	chr14	24188533	Intron	novel		0.45
UCEC	chr14	24183617	Missense_Mutation	novel	A679D	0.3
UCEC	chr14	24186762	Silent	rs773962838	A262A	0.31
UCEC	chr14	24187751	Silent	NA	F108F	0.22
UCEC	chr14	24180542	Missense_Mutation	NA	T1049K	0.26
UCEC	chr14	24184067	Silent	novel	G600G	0.33
UCEC	chr14	24188551	Splice_Site	novel	X52_splice	0.42
UCEC	chr14	24181596	Missense_Mutation	novel	A988T	0.26
UCEC	chr14	24181767	Missense_Mutation	novel	C962R	0.13
UCEC	chr14	24182364	Missense_Mutation	novel	A838T	0.24
UCEC	chr14	24185559	Missense_Mutation	novel	P393H	0.27
UCEC	chr14	24181740	Missense_Mutation	novel	A971T	0.28
UCEC	chr14	24182391	Missense_Mutation	rs763494898	A829T	0.34
UCEC	chr14	24184085	Silent	rs756674360	S594S	0.33
UCEC	chr14	24185925	Missense_Mutation	rs747819166	R369C	0.31
UCEC	chr14	24186436	Missense_Mutation	novel	R286C	0.44
UCEC	chr14	24186751	Missense_Mutation	rs754574474	R266H	0.25
UCEC	chr14	24188256	Missense_Mutation	novel	L80F	0.34	IBN_N
UCEC	chr14	24183002	Missense_Mutation	rs747787561	V799M	0.28
UCEC	chr14	24182333	Frame_Shift_Del	novel	*G848Efs58**	0.29
UCEC	chr14	24188733	Missense_Mutation	rs746325069	E19K	0.36
UCEC	chr14	24183002	Missense_Mutation	rs747787561	V799M	0.49
UCEC	chr14	24180482	Missense_Mutation	novel	D1069G	0.27
UCEC	chr14	24186749	Missense_Mutation	novel	I267V	0.28
UCEC	chr14	24181802	Missense_Mutation	rs770452240	A950V	0.33
UCEC	chr14	24182349	Missense_Mutation	NA	A843T	0.46
UCEC	chr14	24184747	Silent	NA	A513A	0.31
UCEC	chr14	24186150	Frame_Shift_Del	novel	*E347Rfs7**	0.33
UCEC	chr14	24183823	Missense_Mutation	novel	D649N	0.41
UCEC	chr14	24186763	Missense_Mutation	rs369050610	A262V	0.26
UCEC	chr14	24182391	Missense_Mutation	rs763494898	A829T	0.34
UCEC	chr14	24186435	Missense_Mutation	rs753282158	R286H	0.23
UCEC	chr14	24188499	Intron	novel		0.29
UCEC	chr14	24183266	Silent	rs373997560	S737S	0.56
UCEC	chr14	24186762	Silent	rs773962838	A262A	0.27
UCEC	chr14	24180724	Missense_Mutation	novel	C1027Y	0.44
UCEC	chr14	24185256	Missense_Mutation	novel	K445N	0.5
UCEC	chr14	24182140	Missense_Mutation	NA	E874D	0.18
UCEC	chr14	24182002	Silent	novel	I920I	0.3
UCEC	chr14	24184687	Silent	novel	G533G	0.43
UCEC	chr14	24187113	Missense_Mutation	novel	A209V	0.45
UCEC	chr14	24187504	Missense_Mutation	rs756848315	R162W	0.21
UCEC	chr14	24181802	Missense_Mutation	rs770452240	A950V	0.47
UCEC	chr14	24180526	Silent	novel	Q1054Q	0.4
UCEC	chr14	24182807	Silent	novel	E819E	0.32
UCEC	chr14	24188527	Intron	novel		0.3
UCS	chr14	24180239	3'UTR	novel		0.47

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1556	0.19769
CHOL	DEL	0.3611	0.00040262
HNSC	DEL	0.1226	0.0025503
KIRP	DEL	0.1667	0.085174
LUSC	DEL	0.2715	0.0082553
PAAD	DEL	0.0707	0.11332

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00028	Kaplan-Meier Survival Analysis
SARC	0.0018	Kaplan-Meier Survival Analysis
ACC	0.00012	Kaplan-Meier Survival Analysis
SKCM	0.00064	Kaplan-Meier Survival Analysis
READ	0.038	Kaplan-Meier Survival Analysis
KICH	0.03	Kaplan-Meier Survival Analysis
LIHC	0.0001	Kaplan-Meier Survival Analysis
DLBC	0.01	Kaplan-Meier Survival Analysis
LGG	0.024	Kaplan-Meier Survival Analysis
OV	0.031	Kaplan-Meier Survival Analysis

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000196497 (Gene tree)
Gene ID: 79711
Gene Symbol: IPO4
Alias: Imp4|FLJ23338
Full Name: importin 4
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 8,746 bases
Position: chr14:24,180,219-24,188,964
Accession: 19426
RBP type: canonical RBP
Summary: (Importin 4) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include binding and Ran GTPase binding. An important paralog of this gene is IPO5.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000346453	IBN_N	PF03810.19	5.1e-10	1	1
ENSP00000486380	IBN_N	PF03810.19	3.3e-09	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000560222	IPO4-212	573	-	-	- (aa)	-	-
ENST00000561379	IPO4-219	624	-	-	- (aa)	-	-
ENST00000561034	IPO4-216	535	-	ENSP00000452710	48 (aa)	-	H0YK93
ENST00000558780	IPO4-207	3540	-	ENSP00000453108	101 (aa)	-	H0YL92
ENST00000559253	IPO4-208	579	-	ENSP00000453349	98 (aa)	-	H0YLV0
ENST00000558233	IPO4-205	1015	-	ENSP00000453818	312 (aa)	-	H0YN07
ENST00000559588	IPO4-209	3537	-	-	- (aa)	-	-
ENST00000560935	IPO4-215	701	-	-	- (aa)	-	-
ENST00000561199	IPO4-218	3249	-	-	- (aa)	-	-
ENST00000558193	IPO4-204	555	-	-	- (aa)	-	-
ENST00000354464	IPO4-201	3646	-	ENSP00000346453	1081 (aa)	-	Q8TEX9
ENST00000560798	IPO4-214	3581	-	-	- (aa)	-	-
ENST00000558046	IPO4-203	3440	-	ENSP00000452798	154 (aa)	-	H0YKG5
ENST00000558718	IPO4-206	554	-	-	- (aa)	-	-
ENST00000560155	IPO4-211	3485	-	ENSP00000453825	911 (aa)	-	H0YN14
ENST00000557996	IPO4-202	530	-	-	- (aa)	-	-
ENST00000561462	IPO4-220	1864	-	ENSP00000453708	547 (aa)	-	H0YMR4
ENST00000561090	IPO4-217	3632	-	-	- (aa)	-	-
ENST00000560315	IPO4-213	558	-	-	- (aa)	-	-
ENST00000559635	IPO4-210	492	-	-	- (aa)	-	-
ENST00000625289	IPO4-221	297	-	ENSP00000486380	98 (aa)	-	H0YLV0

Gene Model

Click here to download ENSG00000196497's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000196497	Platelet Function Tests	1.6553900E-005	-
ENSG00000196497	Platelet Function Tests	5.2285038E-008	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000196497's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000196497	IPO4	99	45.060	ENSAPOG00000019018	ipo4	99	45.107	Acanthochromis_polyacanthus
ENSG00000196497	IPO4	100	85.767	ENSAMEG00000016271	IPO4	85	84.473	Ailuropoda_melanoleuca
ENSG00000196497	IPO4	99	45.280	ENSACIG00000004246	ipo4	98	44.847	Amphilophus_citrinellus
ENSG00000196497	IPO4	99	44.904	ENSAOCG00000004773	ipo4	99	44.856	Amphiprion_ocellaris
ENSG00000196497	IPO4	99	44.904	ENSAPEG00000002112	ipo4	99	44.856	Amphiprion_percula
ENSG00000196497	IPO4	92	46.116	ENSATEG00000017082	ipo4	99	46.116	Anabas_testudineus
ENSG00000196497	IPO4	88	51.829	ENSACAG00000003973	-	98	54.158	Anolis_carolinensis
ENSG00000196497	IPO4	100	94.542	ENSANAG00000037973	IPO4	100	94.727	Aotus_nancymaae
ENSG00000196497	IPO4	99	44.577	ENSACLG00000019742	ipo4	99	44.712	Astatotilapia_calliptera
ENSG00000196497	IPO4	99	45.028	ENSAMXG00000037878	ipo4	99	44.641	Astyanax_mexicanus
ENSG00000196497	IPO4	100	90.472	ENSBTAG00000002707	IPO4	100	90.472	Bos_taurus
ENSG00000196497	IPO4	100	94.727	ENSCJAG00000006937	IPO4	100	94.912	Callithrix_jacchus
ENSG00000196497	IPO4	100	92.507	ENSCAFG00000012049	IPO4	100	92.229	Canis_familiaris
ENSG00000196497	IPO4	99	91.575	ENSCAFG00020002873	IPO4	100	89.257	Canis_lupus_dingo
ENSG00000196497	IPO4	99	90.648	ENSCHIG00000009413	IPO4	96	90.648	Capra_hircus
ENSG00000196497	IPO4	100	93.062	ENSTSYG00000002643	IPO4	100	93.062	Carlito_syrichta
ENSG00000196497	IPO4	100	88.992	ENSCPOG00000014783	IPO4	100	88.807	Cavia_porcellus
ENSG00000196497	IPO4	100	95.918	ENSCCAG00000037929	IPO4	100	95.918	Cebus_capucinus
ENSG00000196497	IPO4	100	97.959	ENSCATG00000040395	IPO4	100	97.959	Cercocebus_atys
ENSG00000196497	IPO4	100	90.102	ENSCLAG00000012817	IPO4	100	90.287	Chinchilla_lanigera
ENSG00000196497	IPO4	99	48.220	ENSCPBG00000025757	IPO4	94	55.826	Chrysemys_picta_bellii
ENSG00000196497	IPO4	92	37.143	ENSCING00000008639	-	98	36.753	Ciona_intestinalis
ENSG00000196497	IPO4	94	35.618	ENSCSAVG00000011482	-	100	35.203	Ciona_savignyi
ENSG00000196497	IPO4	100	97.225	ENSCANG00000029513	IPO4	100	97.225	Colobus_angolensis_palliatus
ENSG00000196497	IPO4	100	83.904	ENSCGRG00001001217	Ipo4	99	84.053	Cricetulus_griseus_chok1gshd
ENSG00000196497	IPO4	100	83.904	ENSCGRG00000014404	Ipo4	99	84.053	Cricetulus_griseus_crigri
ENSG00000196497	IPO4	99	43.882	ENSCSEG00000009606	ipo4	99	43.918	Cynoglossus_semilaevis
ENSG00000196497	IPO4	99	44.332	ENSCVAG00000002281	ipo4	99	44.055	Cyprinodon_variegatus
ENSG00000196497	IPO4	99	47.043	ENSDARG00000041493	ipo4	98	46.960	Danio_rerio
ENSG00000196497	IPO4	100	90.564	ENSDNOG00000000366	IPO4	100	90.657	Dasypus_novemcinctus
ENSG00000196497	IPO4	100	90.102	ENSDORG00000009274	Ipo4	100	90.194	Dipodomys_ordii
ENSG00000196497	IPO4	100	87.442	ENSETEG00000018381	IPO4	99	87.640	Echinops_telfairi
ENSG00000196497	IPO4	99	86.598	ENSEASG00005011954	IPO4	96	91.641	Equus_asinus_asinus
ENSG00000196497	IPO4	99	93.407	ENSECAG00000009909	IPO4	100	91.674	Equus_caballus
ENSG00000196497	IPO4	99	46.978	ENSELUG00000020628	ipo4	99	46.988	Esox_lucius
ENSG00000196497	IPO4	100	92.784	ENSFCAG00000005587	IPO4	100	92.507	Felis_catus
ENSG00000196497	IPO4	99	84.725	ENSFDAG00000000725	IPO4	99	84.835	Fukomys_damarensis
ENSG00000196497	IPO4	99	40.112	ENSFHEG00000009351	ipo4	97	39.360	Fundulus_heteroclitus
ENSG00000196497	IPO4	99	45.780	ENSGMOG00000001801	ipo4	99	45.767	Gadus_morhua
ENSG00000196497	IPO4	99	44.363	ENSGAFG00000005601	ipo4	99	44.352	Gambusia_affinis
ENSG00000196497	IPO4	99	45.906	ENSGACG00000002276	ipo4	99	45.767	Gasterosteus_aculeatus
ENSG00000196497	IPO4	53	46.680	ENSGAGG00000003383	-	95	45.492	Gopherus_agassizii
ENSG00000196497	IPO4	100	99.075	ENSGGOG00000016062	IPO4	100	99.075	Gorilla_gorilla
ENSG00000196497	IPO4	99	45.438	ENSHBUG00000023269	ipo4	99	45.116	Haplochromis_burtoni
ENSG00000196497	IPO4	100	89.639	ENSHGLG00000002923	IPO4	100	89.732	Heterocephalus_glaber_female
ENSG00000196497	IPO4	100	89.269	ENSHGLG00100003725	IPO4	100	89.362	Heterocephalus_glaber_male
ENSG00000196497	IPO4	99	44.022	ENSHCOG00000016854	ipo4	98	44.231	Hippocampus_comes
ENSG00000196497	IPO4	99	47.016	ENSIPUG00000001185	ipo4	99	46.884	Ictalurus_punctatus
ENSG00000196497	IPO4	100	91.952	ENSSTOG00000002288	IPO4	100	92.137	Ictidomys_tridecemlineatus
ENSG00000196497	IPO4	100	87.893	ENSJJAG00000019002	Ipo4	100	87.985	Jaculus_jaculus
ENSG00000196497	IPO4	99	44.333	ENSKMAG00000004627	ipo4	99	44.527	Kryptolebias_marmoratus
ENSG00000196497	IPO4	99	45.120	ENSLBEG00000024952	ipo4	99	44.981	Labrus_bergylta
ENSG00000196497	IPO4	98	51.852	ENSLACG00000001428	IPO4	98	50.230	Latimeria_chalumnae
ENSG00000196497	IPO4	90	36.559	ENSLOCG00000001149	ipo4	81	47.354	Lepisosteus_oculatus
ENSG00000196497	IPO4	100	88.252	ENSLAFG00000015852	IPO4	100	87.789	Loxodonta_africana
ENSG00000196497	IPO4	100	97.959	ENSMFAG00000000743	IPO4	100	97.959	Macaca_fascicularis
ENSG00000196497	IPO4	100	97.959	ENSMMUG00000012481	IPO4	100	97.959	Macaca_mulatta
ENSG00000196497	IPO4	100	97.959	ENSMNEG00000043531	IPO4	100	97.959	Macaca_nemestrina
ENSG00000196497	IPO4	100	97.959	ENSMLEG00000042067	IPO4	100	97.959	Mandrillus_leucophaeus
ENSG00000196497	IPO4	99	45.018	ENSMAMG00000021976	ipo4	99	44.972	Mastacembelus_armatus
ENSG00000196497	IPO4	99	45.161	ENSMZEG00005017273	ipo4	99	45.116	Maylandia_zebra
ENSG00000196497	IPO4	100	82.348	ENSMAUG00000017565	Ipo4	99	82.943	Mesocricetus_auratus
ENSG00000196497	IPO4	99	92.308	ENSMICG00000001719	IPO4	100	90.816	Microcebus_murinus
ENSG00000196497	IPO4	99	81.256	ENSMOCG00000020462	Ipo4	100	81.423	Microtus_ochrogaster
ENSG00000196497	IPO4	99	44.536	ENSMMOG00000005264	ipo4	99	44.578	Mola_mola
ENSG00000196497	IPO4	99	73.772	ENSMODG00000003337	IPO4	95	73.966	Monodelphis_domestica
ENSG00000196497	IPO4	99	43.893	ENSMALG00000001587	ipo4	99	43.640	Monopterus_albus
ENSG00000196497	IPO4	100	85.714	MGP_CAROLIEiJ_G0019305	Ipo4	100	85.714	Mus_caroli
ENSG00000196497	IPO4	100	83.673	ENSMUSG00000002319	Ipo4	100	83.673	Mus_musculus
ENSG00000196497	IPO4	100	84.694	MGP_PahariEiJ_G0030322	Ipo4	100	84.694	Mus_pahari
ENSG00000196497	IPO4	100	84.694	MGP_SPRETEiJ_G0020194	Ipo4	100	84.694	Mus_spretus
ENSG00000196497	IPO4	100	91.767	ENSMPUG00000005916	IPO4	100	91.674	Mustela_putorius_furo
ENSG00000196497	IPO4	99	88.073	ENSMLUG00000025277	IPO4	86	88.426	Myotis_lucifugus
ENSG00000196497	IPO4	100	89.177	ENSNGAG00000019340	Ipo4	100	89.269	Nannospalax_galili
ENSG00000196497	IPO4	99	45.891	ENSNBRG00000005870	ipo4	99	45.946	Neolamprologus_brichardi
ENSG00000196497	IPO4	100	97.959	ENSNLEG00000015326	IPO4	100	97.959	Nomascus_leucogenys
ENSG00000196497	IPO4	99	90.293	ENSOPRG00000016615	IPO4	100	88.920	Ochotona_princeps
ENSG00000196497	IPO4	100	88.992	ENSODEG00000002609	IPO4	100	88.807	Octodon_degus
ENSG00000196497	IPO4	99	45.714	ENSONIG00000014574	ipo4	99	45.488	Oreochromis_niloticus
ENSG00000196497	IPO4	100	89.104	ENSOCUG00000002881	IPO4	100	89.104	Oryctolagus_cuniculus
ENSG00000196497	IPO4	99	45.046	ENSORLG00000006457	ipo4	99	45.173	Oryzias_latipes
ENSG00000196497	IPO4	99	45.496	ENSORLG00020004286	ipo4	99	45.023	Oryzias_latipes_hni
ENSG00000196497	IPO4	99	45.680	ENSORLG00015021856	ipo4	99	45.267	Oryzias_latipes_hsok
ENSG00000196497	IPO4	99	45.353	ENSOMEG00000016203	ipo4	99	45.353	Oryzias_melastigma
ENSG00000196497	IPO4	99	91.474	ENSOGAG00000010642	IPO4	100	91.103	Otolemur_garnettii
ENSG00000196497	IPO4	100	88.632	ENSOARG00000019188	IPO4	99	89.548	Ovis_aries
ENSG00000196497	IPO4	100	97.959	ENSPPAG00000035476	IPO4	100	97.959	Pan_paniscus
ENSG00000196497	IPO4	100	92.692	ENSPPRG00000023607	IPO4	100	92.414	Panthera_pardus
ENSG00000196497	IPO4	100	92.784	ENSPTIG00000008720	IPO4	100	92.507	Panthera_tigris_altaica
ENSG00000196497	IPO4	100	98.982	ENSPTRG00000006200	IPO4	100	98.982	Pan_troglodytes
ENSG00000196497	IPO4	100	97.959	ENSPANG00000026278	IPO4	100	97.959	Papio_anubis
ENSG00000196497	IPO4	99	46.296	ENSPKIG00000007683	-	98	46.399	Paramormyrops_kingsleyae
ENSG00000196497	IPO4	99	48.070	ENSPKIG00000007830	ipo4	99	48.145	Paramormyrops_kingsleyae
ENSG00000196497	IPO4	99	43.882	ENSPMGG00000020871	ipo4	99	43.918	Periophthalmus_magnuspinnatus
ENSG00000196497	IPO4	100	82.440	ENSPEMG00000016160	Ipo4	100	82.810	Peromyscus_maniculatus_bairdii
ENSG00000196497	IPO4	94	76.228	ENSPCIG00000010718	IPO4	96	76.471	Phascolarctos_cinereus
ENSG00000196497	IPO4	99	44.679	ENSPFOG00000009255	ipo4	99	44.671	Poecilia_formosa
ENSG00000196497	IPO4	99	44.771	ENSPLAG00000020556	ipo4	99	44.764	Poecilia_latipinna
ENSG00000196497	IPO4	99	44.679	ENSPMEG00000013102	ipo4	99	44.671	Poecilia_mexicana
ENSG00000196497	IPO4	99	44.679	ENSPREG00000017605	ipo4	99	44.671	Poecilia_reticulata
ENSG00000196497	IPO4	100	98.520	ENSPPYG00000005688	IPO4	100	98.520	Pongo_abelii
ENSG00000196497	IPO4	99	88.899	ENSPCAG00000015669	IPO4	99	88.899	Procavia_capensis
ENSG00000196497	IPO4	100	93.878	ENSPCOG00000015319	IPO4	100	93.878	Propithecus_coquereli
ENSG00000196497	IPO4	100	91.767	ENSPVAG00000010755	IPO4	100	91.952	Pteropus_vampyrus
ENSG00000196497	IPO4	99	44.977	ENSPNYG00000021414	ipo4	99	45.116	Pundamilia_nyererei
ENSG00000196497	IPO4	99	47.330	ENSPNAG00000027964	ipo4	99	47.437	Pygocentrus_nattereri
ENSG00000196497	IPO4	100	83.087	ENSRNOG00000019553	Ipo4	100	83.272	Rattus_norvegicus
ENSG00000196497	IPO4	100	97.225	ENSRBIG00000027704	IPO4	100	97.225	Rhinopithecus_bieti
ENSG00000196497	IPO4	100	97.225	ENSRROG00000011492	IPO4	100	97.225	Rhinopithecus_roxellana
ENSG00000196497	IPO4	100	95.918	ENSSBOG00000020162	IPO4	100	95.918	Saimiri_boliviensis_boliviensis
ENSG00000196497	IPO4	99	73.383	ENSSHAG00000002619	IPO4	95	73.758	Sarcophilus_harrisii
ENSG00000196497	IPO4	99	46.858	ENSSFOG00015014437	IPO4	98	46.735	Scleropages_formosus
ENSG00000196497	IPO4	99	48.942	ENSSFOG00015012267	ipo4	98	48.747	Scleropages_formosus
ENSG00000196497	IPO4	99	44.485	ENSSMAG00000019912	ipo4	99	44.805	Scophthalmus_maximus
ENSG00000196497	IPO4	99	43.526	ENSSDUG00000017513	ipo4	99	43.123	Seriola_dumerili
ENSG00000196497	IPO4	99	44.894	ENSSLDG00000003869	ipo4	99	44.930	Seriola_lalandi_dorsalis
ENSG00000196497	IPO4	99	79.707	ENSSARG00000010701	IPO4	81	81.592	Sorex_araneus
ENSG00000196497	IPO4	99	44.986	ENSSPAG00000008486	ipo4	99	45.125	Stegastes_partitus
ENSG00000196497	IPO4	100	90.009	ENSSSCG00000002000	IPO4	100	89.454	Sus_scrofa
ENSG00000196497	IPO4	99	44.383	ENSTRUG00000012832	ipo4	98	44.465	Takifugu_rubripes
ENSG00000196497	IPO4	99	43.659	ENSTNIG00000005191	ipo4	99	43.547	Tetraodon_nigroviridis
ENSG00000196497	IPO4	96	92.553	ENSTBEG00000009781	IPO4	100	76.670	Tupaia_belangeri
ENSG00000196497	IPO4	100	88.252	ENSTTRG00000008626	IPO4	100	88.159	Tursiops_truncatus
ENSG00000196497	IPO4	99	90.676	ENSUAMG00000024037	IPO4	99	90.203	Ursus_americanus
ENSG00000196497	IPO4	99	47.523	ENSXETG00000014621	ipo4	98	46.623	Xenopus_tropicalis
ENSG00000196497	IPO4	99	42.857	ENSXCOG00000005208	ipo4	99	43.057	Xiphophorus_couchianus
ENSG00000196497	IPO4	99	43.945	ENSXMAG00000006041	ipo4	99	44.022	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000790	nuclear chromatin	14718166.	IDA	Component
GO:0005515	protein binding	17616579.20805509.22022502.	IPI	Function
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0006335	DNA replication-dependent nucleosome assembly	14718166.	IDA	Process
GO:0006336	DNA replication-independent nucleosome assembly	14718166.	IDA	Process
GO:0006606	protein import into nucleus	11823430.	IDA	Process
GO:0006607	NLS-bearing protein import into nucleus	21873635.	IBA	Process
GO:0006610	ribosomal protein import into nucleus	21873635.	IBA	Process
GO:0008139	nuclear localization sequence binding	21873635.	IBA	Function
GO:0008536	Ran GTPase binding	-	IEA	Function
GO:0008565	protein transporter activity	21873635.	IBA	Function
GO:0016020	membrane	19946888.	HDA	Component
GO:0031965	nuclear membrane	21873635.	IBA	Component
GO:0032991	protein-containing complex	14718166.	IDA	Component
GO:0034399	nuclear periphery	21873635.	IBA	Component

Note: Click here to get the extension of tumor abbreviations.

Note: to get the extension of tumor abbreviations.