EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr22	19721838	Silent	rs558411158	H277H	0.09
BLCA	chr22	19721705	Silent	NA	R261R	0.26
BLCA	chr22	19722570	3'UTR	novel		0.57
BLCA	chr22	19718488	Intron	novel		0.46
BLCA	chr22	19718688	Intron	novel		0.56
BLCA	chr22	19722001	Intron	novel		0.13
BLCA	chr22	19719882	Silent	novel	L76L	0.35
BLCA	chr22	19722264	Silent	NA	E326E	0.33
BRCA	chr22	19719887	Missense_Mutation	NA	A78D	0.1	MMR_HSR1
BRCA	chr22	19720651	Silent	novel	R200R	0.39
BRCA	chr22	19718678	Intron	novel		0.38
BRCA	chr22	19720664	Missense_Mutation	NA	R205W	0.27
BRCA	chr22	19721881	Missense_Mutation	novel	M292L	0.08
BRCA	chr22	19720197	Silent	NA	V107V	0.4
BRCA	chr22	19719660	In_Frame_Del	novel	S38_G42delinsC	0.08	MMR_HSR1
CESC	chr22	19722473	Missense_Mutation	NA	Q367E	0.67
CESC	chr22	19717478	Intron	novel		0.43
CESC	chr22	19721876	Missense_Mutation	NA	T290M	0.2
COAD	chr22	19720212	Silent	novel	F112F	0.33
COAD	chr22	19722019	Intron	NA		0.36
COAD	chr22	19720151	Missense_Mutation	NA	T92M	0.18	MMR_HSR1
COAD	chr22	19721907	Silent	rs759776062	C300C	0.49
COAD	chr22	19720195	Missense_Mutation	NA	V107M	0.17	MMR_HSR1
COAD	chr22	19722006	Intron	NA		0.36
COAD	chr22	19722473	Nonsense_Mutation	NA	Q367*	0.41
COAD	chr22	19721646	Missense_Mutation	rs750628669	A242T	0.15
COAD	chr22	19721987	Intron	NA		0.39
COAD	chr22	19720830	Missense_Mutation	rs370825391	D226E	0.36
COAD	chr22	19720391	Missense_Mutation	NA	R145Q	0.39
COAD	chr22	19722602	3'UTR	novel		0.38
ESCA	chr22	19717399	Intron	novel		0.43
ESCA	chr22	19720338	Silent	novel	D127D	0.3
GBM	chr22	19720795	Missense_Mutation	novel	I215V	0.46
HNSC	chr22	19721670	Missense_Mutation	novel	N250D	0.05
HNSC	chr22	19721872	Missense_Mutation	rs773477864	R289C	0.15
KICH	chr22	19720381	Missense_Mutation	NA	G142S	0.17
KIRC	chr22	19719880	Frame_Shift_Ins	novel	*S77Qfs3**	0.11	MMR_HSR1
KIRP	chr22	19722282	Silent	novel	L332L	0.29
KIRP	chr22	19721907	Silent	rs759776062	C300C	0.37
KIRP	chr22	19722160	Intron	novel		0.22
LGG	chr22	19721920	Missense_Mutation	novel	E305K	0.37
LIHC	chr22	19720431	Silent	novel	Y158Y	0.31
LIHC	chr22	19721841	Silent	novel	C278C	0.05
LUAD	chr22	19720814	Missense_Mutation	NA	P221L	0.39
LUAD	chr22	19719623	Missense_Mutation	NA	G26C	0.43	MMR_HSR1
LUAD	chr22	19719846	Silent	NA	L64L	0.19
LUAD	chr22	19721704	Missense_Mutation	NA	R261Q	0.27
LUAD	chr22	19720201	Missense_Mutation	novel	T109S	0.2	MMR_HSR1
LUSC	chr22	19720606	Silent	novel	V185V	0.21
LUSC	chr22	19720612	Silent	novel	L187L	0.24
LUSC	chr22	19719844	Frame_Shift_Del	novel	*L64Tfs19**	0.08	MMR_HSR1
LUSC	chr22	19719818	Missense_Mutation	novel	L55R	0.34	MMR_HSR1
LUSC	chr22	19721696	Missense_Mutation	novel	Q258H	0.43
LUSC	chr22	19719660	Missense_Mutation	rs776341079	S38L	0.1	MMR_HSR1
OV	chr22	19720798	Missense_Mutation	novel	H216Y	0.15
PAAD	chr22	19718666	Intron	novel		0.17
PAAD	chr22	19720212	Silent	novel	F112F	0.15
PAAD	chr22	19720553	Missense_Mutation	rs201668611	R168W	0.22
PAAD	chr22	19721857	Missense_Mutation	rs772586066	R284C	0.22
PRAD	chr22	19722472	Missense_Mutation	novel	M366I	0.26
SARC	chr22	19720442	Missense_Mutation	NA	P162L	0.32
SARC	chr22	19719661	Silent	rs142143618	S38S	0.09
SKCM	chr22	19722065	Intron	novel		0.3
SKCM	chr22	19721824	Missense_Mutation	NA	E273K	0.34
SKCM	chr22	19720443	Silent	rs756651250	P162P	0.25
SKCM	chr22	19721703	Missense_Mutation	NA	R261W	0.37
SKCM	chr22	19722228	Intron	novel		0.17
SKCM	chr22	19718553	Intron	novel		0.28
SKCM	chr22	19719670	Missense_Mutation	NA	K41N	0.13	MMR_HSR1
SKCM	chr22	19720388	Missense_Mutation	NA	N144S	0.3
SKCM	chr22	19720368	Silent	NA	F137F	0.29
SKCM	chr22	19720194	Frame_Shift_Del	novel	*V107Afs25**	0.09	MMR_HSR1
SKCM	chr22	19718567	Intron	novel		0.19
SKCM	chr22	19721835	Silent	novel	A276A	0.1
SKCM	chr22	19719819	Silent	NA	L55L	0.14
SKCM	chr22	19720368	Silent	NA	F137F	0.49
STAD	chr22	19720381	Missense_Mutation	NA	G142S	0.08
STAD	chr22	19718670	Intron	novel		0.32
STAD	chr22	19721662	Missense_Mutation	NA	I247T	0.31
STAD	chr22	19721876	Missense_Mutation	NA	T290M	0.19
STAD	chr22	19718577	Intron	novel		0.26
STAD	chr22	19720422	Silent	NA	C155C	0.06
THCA	chr22	19722068	Intron	novel		0.75
THCA	chr22	19720599	Missense_Mutation	rs768217482	N183S	0.25
UCEC	chr22	19721847	Silent	rs779266097	F280F	0.39
UCEC	chr22	19719609	Missense_Mutation	novel	D21G	0.22	MMR_HSR1
UCEC	chr22	19721702	Silent	novel	V260V	0.3
UCEC	chr22	19720784	Missense_Mutation	novel	D211G	0.33
UCEC	chr22	19721730	Missense_Mutation	novel	V270M	0.12
UCEC	chr22	19717572	Intron	novel		0.6
UCEC	chr22	19720380	Silent	rs369695421	S141S	0.45
UCEC	chr22	19721872	Missense_Mutation	rs773477864	R289C	0.2
UCEC	chr22	19720553	Missense_Mutation	rs201668611	R168W	0.21
UCEC	chr22	19717487	Intron	novel		0.5
UCEC	chr22	19722454	Silent	novel	Q360Q	0.3
UCEC	chr22	19721655	Missense_Mutation	rs760908390	A245T	0.36
UCEC	chr22	19720327	Missense_Mutation	NA	P124S	0.15	MMR_HSR1
UCEC	chr22	19720219	Missense_Mutation	novel	A115T	0.44	MMR_HSR1
UCEC	chr22	19719859	Missense_Mutation	novel	L69V	0.48	MMR_HSR1
UCEC	chr22	19721694	Nonsense_Mutation	NA	Q258*	0.16
UCEC	chr22	19721933	Missense_Mutation	novel	A309V	0.47
UCEC	chr22	19721658	Missense_Mutation	novel	V246I	0.06
UCEC	chr22	19720801	Missense_Mutation	NA	V217I	0.83
UCEC	chr22	19719699	Splice_Site	novel	X51_splice	0.38
UCEC	chr22	19721868	Silent	NA	L287L	0.27
UCEC	chr22	19721857	Missense_Mutation	rs772586066	R284C	0.37
UCEC	chr22	19722445	Missense_Mutation	NA	E357D	0.25
UCEC	chr22	19717400	Intron	novel		0.34
UCEC	chr22	19720858	Missense_Mutation	novel	R236W	0.24
UCEC	chr22	19719844	Missense_Mutation	novel	L64I	0.4	MMR_HSR1
UCS	chr22	19721697	Missense_Mutation	rs745550752	R259W	0.23

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
LUSC	AMP	0.3892	2.9109e-05
LUSC	DEL	0.1178	0.0093511
TGCT	AMP	0.3533	5.309e-06
THCA	AMP	0.008	0.056221

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00012	Kaplan-Meier Survival Analysis
STAD	0.017	Kaplan-Meier Survival Analysis
MESO	0.0023	Kaplan-Meier Survival Analysis
ACC	0.00011	Kaplan-Meier Survival Analysis
SKCM	0.0047	Kaplan-Meier Survival Analysis
COAD	0.044	Kaplan-Meier Survival Analysis
PAAD	0.0014	Kaplan-Meier Survival Analysis
BLCA	0.018	Kaplan-Meier Survival Analysis
READ	0.034	Kaplan-Meier Survival Analysis
UCEC	0.016	Kaplan-Meier Survival Analysis
LIHC	0.0086	Kaplan-Meier Survival Analysis
LGG	0.0011	Kaplan-Meier Survival Analysis
UVM	0.013	Kaplan-Meier Survival Analysis

Description

RBDs

Expression

Transcripts

Gene Model

Pathway

PPI

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000184702 (Gene tree)
Gene ID: 5413
Gene Symbol: SEPT5
Alias: HCDCREL-1|H5|PNUTL1
Full Name: septin 5
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Plus strand
Length: 9,761 bases
Position: chr22:19,714,464-19,724,224
Accession: 9164
Summary: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000378541	MMR_HSR1	PF01926.23	4.2e-06	1	1
ENSP00000414488	MMR_HSR1	PF01926.23	5.3e-06	1	1
ENSP00000391311	MMR_HSR1	PF01926.23	6.9e-06	1	1
ENSP00000384535	MMR_HSR1	PF01926.23	7e-06	1	1
ENSP00000372515	MMR_HSR1	PF01926.23	7.3e-06	1	1
ENSP00000394541	MMR_HSR1	PF01926.23	7.4e-06	1	1
ENSP00000408678	MMR_HSR1	PF01926.23	9.7e-06	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000431124	SEPT5-207	920	-	ENSP00000414488	304 (aa)	-	E7EPG2
ENST00000438754	SEPT5-208	2241	-	ENSP00000394541	346 (aa)	-	Q99719
ENST00000406172	SEPT5-203	1996	-	ENSP00000385356	248 (aa)	-	E7EQM7
ENST00000383045	SEPT5-201	1588	-	ENSP00000372515	378 (aa)	-	G3XAH0
ENST00000480423	SEPT5-212	563	-	-	- (aa)	-	-
ENST00000490204	SEPT5-213	774	-	-	- (aa)	-	-
ENST00000455784	SEPT5-209	2070	-	ENSP00000391311	369 (aa)	-	Q99719
ENST00000406395	SEPT5-204	1974	-	ENSP00000384535	337 (aa)	-	E7EX32
ENST00000470814	SEPT5-210	2353	-	-	- (aa)	-	-
ENST00000412544	SEPT5-205	1108	-	ENSP00000408678	301 (aa)	-	C9JM82
ENST00000395109	SEPT5-202	794	-	ENSP00000378541	180 (aa)	-	F8W9E5
ENST00000477238	SEPT5-211	577	-	-	- (aa)	-	-
ENST00000413258	SEPT5-206	318	-	ENSP00000404673	106 (aa)	-	H7C299

Gene Model

Click here to download ENSG00000184702's gene model file

Pathway

Pathway ID	Pathway Name	Source
hsa05012	Parkinson disease	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000184702's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000184702	SEPT5	100	91.667	ENSAPOG00000021568	sept5a	99	85.366	Acanthochromis_polyacanthus
ENSG00000184702	SEPT5	100	87.222	ENSAPOG00000004707	sept5b	98	79.133	Acanthochromis_polyacanthus
ENSG00000184702	SEPT5	100	98.007	ENSAMEG00000011509	-	87	94.215	Ailuropoda_melanoleuca
ENSG00000184702	SEPT5	100	87.778	ENSACIG00000000964	-	99	78.693	Amphilophus_citrinellus
ENSG00000184702	SEPT5	100	91.667	ENSACIG00000006554	sept5a	97	89.143	Amphilophus_citrinellus
ENSG00000184702	SEPT5	100	87.222	ENSAOCG00000019424	sept5b	93	85.387	Amphiprion_ocellaris
ENSG00000184702	SEPT5	100	91.667	ENSAOCG00000015062	sept5a	99	85.366	Amphiprion_ocellaris
ENSG00000184702	SEPT5	100	91.667	ENSAPEG00000017611	sept5a	99	85.366	Amphiprion_percula
ENSG00000184702	SEPT5	100	87.222	ENSAPEG00000008250	sept5b	98	79.675	Amphiprion_percula
ENSG00000184702	SEPT5	100	86.667	ENSATEG00000006356	sept5b	98	83.056	Anabas_testudineus
ENSG00000184702	SEPT5	100	91.667	ENSATEG00000020583	sept5a	99	85.637	Anabas_testudineus
ENSG00000184702	SEPT5	100	95.017	ENSAPLG00000016224	-	100	94.587	Anas_platyrhynchos
ENSG00000184702	SEPT5	100	95.681	ENSACAG00000000290	-	82	93.767	Anolis_carolinensis
ENSG00000184702	SEPT5	100	100.000	ENSANAG00000025950	-	100	100.000	Aotus_nancymaae
ENSG00000184702	SEPT5	100	86.667	ENSACLG00000008299	sept5b	99	80.759	Astatotilapia_calliptera
ENSG00000184702	SEPT5	100	91.667	ENSACLG00000011272	sept5a	97	89.112	Astatotilapia_calliptera
ENSG00000184702	SEPT5	100	88.889	ENSAMXG00000006159	sept5a	99	85.366	Astyanax_mexicanus
ENSG00000184702	SEPT5	100	99.003	ENSBTAG00000008320	SEPT5	100	98.413	Bos_taurus
ENSG00000184702	SEPT5	100	100.000	ENSCJAG00000031147	-	100	100.000	Callithrix_jacchus
ENSG00000184702	SEPT5	100	99.336	ENSCAFG00000014533	SEPT5	100	99.206	Canis_familiaris
ENSG00000184702	SEPT5	100	99.336	ENSCAFG00020007897	-	100	99.206	Canis_lupus_dingo
ENSG00000184702	SEPT5	100	95.580	ENSCHIG00000000129	-	92	91.185	Capra_hircus
ENSG00000184702	SEPT5	100	99.003	ENSTSYG00000037551	-	100	98.677	Carlito_syrichta
ENSG00000184702	SEPT5	100	97.778	ENSCAPG00000006545	-	100	98.697	Cavia_aperea
ENSG00000184702	SEPT5	100	98.677	ENSCPOG00000010483	-	100	98.677	Cavia_porcellus
ENSG00000184702	SEPT5	100	100.000	ENSCCAG00000036918	-	100	100.000	Cebus_capucinus
ENSG00000184702	SEPT5	100	100.000	ENSCATG00000040593	-	100	100.000	Cercocebus_atys
ENSG00000184702	SEPT5	100	98.148	ENSCLAG00000015333	-	100	98.148	Chinchilla_lanigera
ENSG00000184702	SEPT5	100	100.000	ENSCSAG00000011732	-	100	100.000	Chlorocebus_sabaeus
ENSG00000184702	SEPT5	100	96.111	ENSCPBG00000010660	-	100	94.851	Chrysemys_picta_bellii
ENSG00000184702	SEPT5	100	100.000	ENSCANG00000030373	-	100	99.464	Colobus_angolensis_palliatus
ENSG00000184702	SEPT5	100	99.003	ENSCGRG00001018409	-	100	98.916	Cricetulus_griseus_chok1gshd
ENSG00000184702	SEPT5	100	99.003	ENSCGRG00000011656	-	93	96.000	Cricetulus_griseus_crigri
ENSG00000184702	SEPT5	100	91.111	ENSCSEG00000019641	sept5a	99	85.100	Cynoglossus_semilaevis
ENSG00000184702	SEPT5	100	89.444	ENSCSEG00000009877	-	91	87.162	Cynoglossus_semilaevis
ENSG00000184702	SEPT5	100	91.667	ENSCVAG00000017986	sept5a	98	87.115	Cyprinodon_variegatus
ENSG00000184702	SEPT5	100	87.778	ENSDARG00000013843	sept5a	90	84.282	Danio_rerio
ENSG00000184702	SEPT5	100	87.778	ENSDARG00000036031	sept5b	100	84.133	Danio_rerio
ENSG00000184702	SEPT5	100	99.336	ENSDORG00000013930	-	100	99.187	Dipodomys_ordii
ENSG00000184702	SEPT5	100	98.007	ENSEASG00005010502	-	96	97.826	Equus_asinus_asinus
ENSG00000184702	SEPT5	100	98.671	ENSECAG00000020718	-	70	98.374	Equus_caballus
ENSG00000184702	SEPT5	100	89.444	ENSELUG00000009028	sept5a	99	84.085	Esox_lucius
ENSG00000184702	SEPT5	100	87.778	ENSELUG00000005164	sept5b	99	82.289	Esox_lucius
ENSG00000184702	SEPT5	100	99.003	ENSFCAG00000035936	-	100	97.561	Felis_catus
ENSG00000184702	SEPT5	100	96.111	ENSFALG00000008028	-	100	93.767	Ficedula_albicollis
ENSG00000184702	SEPT5	100	98.671	ENSFDAG00000014909	-	100	98.588	Fukomys_damarensis
ENSG00000184702	SEPT5	100	91.667	ENSFHEG00000018533	sept5a	98	88.286	Fundulus_heteroclitus
ENSG00000184702	SEPT5	100	72.848	ENSFHEG00000003693	sept5b	99	74.013	Fundulus_heteroclitus
ENSG00000184702	SEPT5	100	95.556	ENSGALG00000001688	SEPT5	100	92.954	Gallus_gallus
ENSG00000184702	SEPT5	100	91.667	ENSGAFG00000000767	sept5a	98	89.398	Gambusia_affinis
ENSG00000184702	SEPT5	100	85.556	ENSGAFG00000007663	sept5b	90	79.545	Gambusia_affinis
ENSG00000184702	SEPT5	100	91.667	ENSGACG00000005538	sept5a	98	88.761	Gasterosteus_aculeatus
ENSG00000184702	SEPT5	100	96.111	ENSGAGG00000014385	-	100	92.670	Gopherus_agassizii
ENSG00000184702	SEPT5	100	100.000	ENSGGOG00000016545	-	100	100.000	Gorilla_gorilla
ENSG00000184702	SEPT5	100	87.222	ENSHBUG00000007908	sept5b	99	81.030	Haplochromis_burtoni
ENSG00000184702	SEPT5	68	91.803	ENSHBUG00000013963	sept5a	93	92.617	Haplochromis_burtoni
ENSG00000184702	SEPT5	100	98.671	ENSHGLG00000013741	-	100	98.645	Heterocephalus_glaber_female
ENSG00000184702	SEPT5	100	91.111	ENSHCOG00000005881	sept5a	99	85.366	Hippocampus_comes
ENSG00000184702	SEPT5	100	78.405	ENSIPUG00000025006	sept5a	94	59.593	Ictalurus_punctatus
ENSG00000184702	SEPT5	100	99.668	ENSSTOG00000010725	-	100	99.471	Ictidomys_tridecemlineatus
ENSG00000184702	SEPT5	100	99.003	ENSJJAG00000000091	-	100	98.916	Jaculus_jaculus
ENSG00000184702	SEPT5	100	91.667	ENSKMAG00000003408	sept5a	99	85.908	Kryptolebias_marmoratus
ENSG00000184702	SEPT5	100	90.556	ENSLBEG00000025389	sept5a	99	85.366	Labrus_bergylta
ENSG00000184702	SEPT5	100	85.000	ENSLBEG00000028216	-	92	83.815	Labrus_bergylta
ENSG00000184702	SEPT5	100	92.222	ENSLACG00000015559	sept5b	100	84.304	Latimeria_chalumnae
ENSG00000184702	SEPT5	100	99.003	ENSLAFG00000028004	-	100	98.113	Loxodonta_africana
ENSG00000184702	SEPT5	100	100.000	ENSMFAG00000038117	-	100	100.000	Macaca_fascicularis
ENSG00000184702	SEPT5	100	100.000	ENSMMUG00000017134	-	100	100.000	Macaca_mulatta
ENSG00000184702	SEPT5	100	100.000	ENSMNEG00000036305	-	100	100.000	Macaca_nemestrina
ENSG00000184702	SEPT5	100	100.000	ENSMLEG00000029088	-	100	100.000	Mandrillus_leucophaeus
ENSG00000184702	SEPT5	100	91.667	ENSMAMG00000014426	sept5a	99	85.637	Mastacembelus_armatus
ENSG00000184702	SEPT5	100	86.667	ENSMAMG00000006704	sept5b	99	82.102	Mastacembelus_armatus
ENSG00000184702	SEPT5	100	91.667	ENSMZEG00005009762	sept5a	97	87.675	Maylandia_zebra
ENSG00000184702	SEPT5	100	86.667	ENSMZEG00005011980	sept5b	96	83.862	Maylandia_zebra
ENSG00000184702	SEPT5	100	93.069	ENSMGAG00000001319	-	96	92.938	Meleagris_gallopavo
ENSG00000184702	SEPT5	100	99.003	ENSMAUG00000014786	-	100	98.916	Mesocricetus_auratus
ENSG00000184702	SEPT5	100	99.003	ENSMICG00000028407	-	100	98.677	Microcebus_murinus
ENSG00000184702	SEPT5	100	99.003	ENSMOCG00000000071	-	100	98.916	Microtus_ochrogaster
ENSG00000184702	SEPT5	100	84.444	ENSMMOG00000010567	sept5b	99	78.049	Mola_mola
ENSG00000184702	SEPT5	100	91.667	ENSMMOG00000011704	sept5a	99	89.112	Mola_mola
ENSG00000184702	SEPT5	100	91.667	ENSMALG00000020359	sept5a	98	93.836	Monopterus_albus
ENSG00000184702	SEPT5	100	84.444	ENSMALG00000005830	sept5b	99	82.633	Monopterus_albus
ENSG00000184702	SEPT5	100	99.003	MGP_CAROLIEiJ_G0020551	-	100	98.916	Mus_caroli
ENSG00000184702	SEPT5	100	99.003	ENSMUSG00000072214	Sept5	100	98.942	Mus_musculus
ENSG00000184702	SEPT5	100	99.003	ENSMUSG00000116594	AC133488.1	99	99.167	Mus_musculus
ENSG00000184702	SEPT5	100	99.003	MGP_PahariEiJ_G0016256	-	100	98.916	Mus_pahari
ENSG00000184702	SEPT5	100	99.003	MGP_SPRETEiJ_G0021446	-	100	98.942	Mus_spretus
ENSG00000184702	SEPT5	100	99.336	ENSMPUG00000003893	-	100	99.068	Mustela_putorius_furo
ENSG00000184702	SEPT5	100	99.003	ENSMLUG00000002506	-	96	98.942	Myotis_lucifugus
ENSG00000184702	SEPT5	100	99.336	ENSNGAG00000013782	-	100	99.187	Nannospalax_galili
ENSG00000184702	SEPT5	100	86.667	ENSNBRG00000004761	sept5b	96	83.862	Neolamprologus_brichardi
ENSG00000184702	SEPT5	100	91.667	ENSNBRG00000018717	sept5a	97	89.112	Neolamprologus_brichardi
ENSG00000184702	SEPT5	100	100.000	ENSNLEG00000005511	-	100	99.074	Nomascus_leucogenys
ENSG00000184702	SEPT5	100	96.111	ENSMEUG00000015556	-	100	95.726	Notamacropus_eugenii
ENSG00000184702	SEPT5	100	95.349	ENSOPRG00000007708	-	100	95.726	Ochotona_princeps
ENSG00000184702	SEPT5	100	98.671	ENSODEG00000016498	-	100	98.645	Octodon_degus
ENSG00000184702	SEPT5	100	87.222	ENSONIG00000011388	sept5b	99	81.301	Oreochromis_niloticus
ENSG00000184702	SEPT5	100	83.889	ENSORLG00000001081	sept5b	98	81.440	Oryzias_latipes
ENSG00000184702	SEPT5	100	91.667	ENSORLG00000024104	sept5a	98	89.112	Oryzias_latipes
ENSG00000184702	SEPT5	100	83.333	ENSORLG00020016872	sept5b	94	82.808	Oryzias_latipes_hni
ENSG00000184702	SEPT5	100	91.667	ENSORLG00020005445	sept5a	98	89.112	Oryzias_latipes_hni
ENSG00000184702	SEPT5	100	91.667	ENSORLG00015015192	sept5a	99	85.637	Oryzias_latipes_hsok
ENSG00000184702	SEPT5	100	83.333	ENSORLG00015003711	sept5b	98	81.440	Oryzias_latipes_hsok
ENSG00000184702	SEPT5	99	84.270	ENSOMEG00000022819	sept5b	89	82.963	Oryzias_melastigma
ENSG00000184702	SEPT5	100	91.667	ENSOMEG00000017874	sept5a	99	89.112	Oryzias_melastigma
ENSG00000184702	SEPT5	100	99.003	ENSOGAG00000026834	-	99	95.640	Otolemur_garnettii
ENSG00000184702	SEPT5	66	95.798	ENSOARG00000001444	-	90	95.798	Ovis_aries
ENSG00000184702	SEPT5	100	100.000	ENSPPAG00000042516	-	100	100.000	Pan_paniscus
ENSG00000184702	SEPT5	100	99.668	ENSPPRG00000002930	-	100	99.471	Panthera_pardus
ENSG00000184702	SEPT5	100	99.668	ENSPTIG00000019967	-	100	99.471	Panthera_tigris_altaica
ENSG00000184702	SEPT5	100	100.000	ENSPTRG00000014066	-	100	100.000	Pan_troglodytes
ENSG00000184702	SEPT5	100	100.000	ENSPANG00000001023	-	100	100.000	Papio_anubis
ENSG00000184702	SEPT5	100	91.667	ENSPKIG00000024641	sept5b	99	87.805	Paramormyrops_kingsleyae
ENSG00000184702	SEPT5	100	95.681	ENSPSIG00000002889	-	100	95.342	Pelodiscus_sinensis
ENSG00000184702	SEPT5	100	87.222	ENSPMGG00000021306	sept5b	98	83.333	Periophthalmus_magnuspinnatus
ENSG00000184702	SEPT5	100	91.667	ENSPMGG00000018375	sept5a	99	86.339	Periophthalmus_magnuspinnatus
ENSG00000184702	SEPT5	100	99.003	ENSPEMG00000013636	-	100	98.870	Peromyscus_maniculatus_bairdii
ENSG00000184702	SEPT5	100	91.667	ENSPFOG00000011811	sept5a	99	86.179	Poecilia_formosa
ENSG00000184702	SEPT5	100	85.556	ENSPFOG00000016894	sept5b	98	81.111	Poecilia_formosa
ENSG00000184702	SEPT5	100	91.667	ENSPLAG00000018547	sept5a	98	89.685	Poecilia_latipinna
ENSG00000184702	SEPT5	100	85.000	ENSPLAG00000005877	sept5b	99	79.620	Poecilia_latipinna
ENSG00000184702	SEPT5	100	85.556	ENSPMEG00000017826	sept5b	96	79.184	Poecilia_mexicana
ENSG00000184702	SEPT5	100	91.667	ENSPMEG00000004070	sept5a	99	85.908	Poecilia_mexicana
ENSG00000184702	SEPT5	100	91.667	ENSPREG00000011585	sept5a	99	85.450	Poecilia_reticulata
ENSG00000184702	SEPT5	100	85.083	ENSPREG00000013868	sept5b	97	79.245	Poecilia_reticulata
ENSG00000184702	SEPT5	100	99.444	ENSPPYG00000011583	-	87	99.550	Pongo_abelii
ENSG00000184702	SEPT5	100	99.003	ENSPCOG00000012479	-	100	98.916	Propithecus_coquereli
ENSG00000184702	SEPT5	100	99.336	ENSPVAG00000012974	-	93	93.634	Pteropus_vampyrus
ENSG00000184702	SEPT5	100	91.667	ENSPNYG00000008373	sept5a	97	89.112	Pundamilia_nyererei
ENSG00000184702	SEPT5	100	86.667	ENSPNYG00000010341	sept5b	99	83.621	Pundamilia_nyererei
ENSG00000184702	SEPT5	100	89.369	ENSPNAG00000001270	sept5b	99	86.179	Pygocentrus_nattereri
ENSG00000184702	SEPT5	100	89.444	ENSPNAG00000007785	sept5a	99	85.908	Pygocentrus_nattereri
ENSG00000184702	SEPT5	100	98.677	ENSRNOG00000029912	Sept5	100	98.677	Rattus_norvegicus
ENSG00000184702	SEPT5	100	100.000	ENSRBIG00000041362	-	100	100.000	Rhinopithecus_bieti
ENSG00000184702	SEPT5	100	100.000	ENSRROG00000041246	-	100	100.000	Rhinopithecus_roxellana
ENSG00000184702	SEPT5	100	100.000	ENSSBOG00000027910	-	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000184702	SEPT5	100	96.111	ENSSHAG00000011753	-	92	95.130	Sarcophilus_harrisii
ENSG00000184702	SEPT5	100	91.111	ENSSFOG00015014043	sept5	98	90.258	Scleropages_formosus
ENSG00000184702	SEPT5	100	91.667	ENSSMAG00000006148	sept5a	99	85.185	Scophthalmus_maximus
ENSG00000184702	SEPT5	100	87.778	ENSSMAG00000009333	sept5b	98	83.056	Scophthalmus_maximus
ENSG00000184702	SEPT5	100	91.667	ENSSDUG00000002398	sept5a	97	89.177	Seriola_dumerili
ENSG00000184702	SEPT5	100	86.667	ENSSDUG00000006594	sept5b	99	81.843	Seriola_dumerili
ENSG00000184702	SEPT5	100	87.222	ENSSLDG00000005541	sept5b	76	84.211	Seriola_lalandi_dorsalis
ENSG00000184702	SEPT5	100	91.667	ENSSLDG00000003964	sept5a	97	87.446	Seriola_lalandi_dorsalis
ENSG00000184702	SEPT5	100	95.017	ENSSPUG00000015346	-	100	94.587	Sphenodon_punctatus
ENSG00000184702	SEPT5	100	91.667	ENSSPAG00000015627	sept5a	99	84.921	Stegastes_partitus
ENSG00000184702	SEPT5	100	88.333	ENSSPAG00000000073	sept5b	93	86.246	Stegastes_partitus
ENSG00000184702	SEPT5	100	99.003	ENSSSCG00000010128	-	100	92.118	Sus_scrofa
ENSG00000184702	SEPT5	100	95.556	ENSTGUG00000008412	-	96	92.147	Taeniopygia_guttata
ENSG00000184702	SEPT5	100	85.000	ENSTRUG00000018608	sept5b	98	80.165	Takifugu_rubripes
ENSG00000184702	SEPT5	100	90.556	ENSTRUG00000016478	sept5a	97	88.728	Takifugu_rubripes
ENSG00000184702	SEPT5	100	84.444	ENSTNIG00000013578	sept5b	99	79.730	Tetraodon_nigroviridis
ENSG00000184702	SEPT5	100	86.188	ENSTNIG00000015926	sept5a	99	80.161	Tetraodon_nigroviridis
ENSG00000184702	SEPT5	100	99.336	ENSUAMG00000011220	-	100	99.206	Ursus_americanus
ENSG00000184702	SEPT5	100	99.336	ENSVVUG00000025380	-	88	99.148	Vulpes_vulpes
ENSG00000184702	SEPT5	100	95.017	ENSXETG00000030888	sept5	100	92.141	Xenopus_tropicalis
ENSG00000184702	SEPT5	100	91.111	ENSXCOG00000002175	sept5a	99	89.112	Xiphophorus_couchianus
ENSG00000184702	SEPT5	100	85.083	ENSXCOG00000016246	sept5b	97	82.759	Xiphophorus_couchianus
ENSG00000184702	SEPT5	100	85.083	ENSXMAG00000016115	sept5b	97	82.759	Xiphophorus_maculatus
ENSG00000184702	SEPT5	100	91.111	ENSXMAG00000014644	sept5a	98	89.112	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003924	GTPase activity	21873635.	IBA	Function
GO:0003924	GTPase activity	21563316.	TAS	Function
GO:0005198	structural molecule activity	9611266.	TAS	Function
GO:0005515	protein binding	10321247.16767699.18330356.25416956.	IPI	Function
GO:0005525	GTP binding	-	IEA	Function
GO:0005886	plasma membrane	10321247.	IDA	Component
GO:0005940	septin ring	21873635.	IBA	Component
GO:0008021	synaptic vesicle	21873635.	IBA	Component
GO:0008021	synaptic vesicle	10321247.	IDA	Component
GO:0015630	microtubule cytoskeleton	21873635.	IBA	Component
GO:0016080	synaptic vesicle targeting	10321247.	TAS	Process
GO:0017157	regulation of exocytosis	21873635.	IBA	Process
GO:0017157	regulation of exocytosis	10321247.	IMP	Process
GO:0030534	adult behavior	-	ISS	Process
GO:0031105	septin complex	21873635.	IBA	Component
GO:0031105	septin complex	-	ISS	Component
GO:0035176	social behavior	-	ISS	Process
GO:0060090	molecular adaptor activity	21873635.	IBA	Function
GO:0061640	cytoskeleton-dependent cytokinesis	21873635.	IBA	Process
GO:2000300	regulation of synaptic vesicle exocytosis	21563316.	TAS	Process

Note: Click here to get the extension of tumor abbreviations.

Note: to get the extension of tumor abbreviations.