EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr12	122605033	Missense_Mutation	rs542508586	E1778K	0.52
BLCA	chr12	122561950	Silent	novel	L506L	0.23
BLCA	chr12	122615072	Missense_Mutation	novel	L1987V	0.14
BLCA	chr12	122551363	Splice_Site	novel	X377_splice	0.41
BLCA	chr12	122587827	Missense_Mutation	novel	L1283F	0.51
BLCA	chr12	122562642	Missense_Mutation	novel	L516R	0.58
BLCA	chr12	122579941	Missense_Mutation	novel	V960L	0.2
BLCA	chr12	122618381	Silent	novel	Q2023Q	0.24
BLCA	chr12	122538422	Missense_Mutation	novel	H112Y	0.43
BLCA	chr12	122586700	Splice_Site	rs779572734	X1225_splice	0.21
BLCA	chr12	122610890	Missense_Mutation	NA	S1871L	0.21
BLCA	chr12	122584309	Missense_Mutation	novel	T1099S	0.47
BLCA	chr12	122587812	Missense_Mutation	NA	S1278A	0.09
BLCA	chr12	122594362	Silent	NA	T1444T	0.37
BLCA	chr12	122584450	Missense_Mutation	novel	D1146N	0.16
BLCA	chr12	122602874	Missense_Mutation	novel	S1624W	0.35
BLCA	chr12	122604571	Missense_Mutation	novel	F1703L	0.11
BLCA	chr12	122602674	Frame_Shift_Del	novel	*A1587Pfs3**	0.25
BLCA	chr12	122573227	Missense_Mutation	novel	R742K	0.06
BLCA	chr12	122577777	Missense_Mutation	novel	D943H	0.23
BLCA	chr12	122604957	Silent	NA	L1752L	0.46
BRCA	chr12	122584953	Missense_Mutation	NA	R1166K	0.21
BRCA	chr12	122582874	Missense_Mutation	novel	K1051R	0.15
BRCA	chr12	122530073	Missense_Mutation	NA	D4Y	0.3
BRCA	chr12	122574293	Silent	rs768380870	N765N	0.1
BRCA	chr12	122620468	Intron	novel		0.13
BRCA	chr12	122622469	Missense_Mutation	NA	S2126T	0.14
BRCA	chr12	122584329	Silent	NA	L1105L	0.38
BRCA	chr12	122575853	Missense_Mutation	rs769739544	R847Q	0.15
BRCA	chr12	122577029	Splice_Region	NA	Q907Q	0.29
BRCA	chr12	122580608	Missense_Mutation	NA	L974V	0.38
BRCA	chr12	122604887	Missense_Mutation	rs766109359	R1729H	0.33
BRCA	chr12	122604608	Nonsense_Mutation	NA	E1716*	0.14
BRCA	chr12	122604898	Missense_Mutation	novel	E1733Q	0.06
CESC	chr12	122539733	Missense_Mutation	novel	E142Q	0.35
CESC	chr12	122574304	Nonsense_Mutation	NA	S769*	0.15
CESC	chr12	122573241	Missense_Mutation	NA	E747Q	0.27
CESC	chr12	122573167	Missense_Mutation	NA	R722Q	0.33
CESC	chr12	122577780	Missense_Mutation	NA	H944N	0.43
CESC	chr12	122568298	Missense_Mutation	NA	D548N	0.43
CESC	chr12	122549827	Missense_Mutation	rs147259173	S350F	0.37
CESC	chr12	122602875	Silent	NA	S1624S	0.26
CESC	chr12	122594351	Missense_Mutation	NA	D1441H	0.4
CESC	chr12	122603153	Frame_Shift_Ins	novel	*T1671Sfs30**	0.23
CESC	chr12	122603154	Missense_Mutation	novel	T1671K	0.23
CESC	chr12	122586741	Silent	novel	Y1238Y	0.31
CESC	chr12	122534758	Missense_Mutation	NA	R75T	0.11
CESC	chr12	122604880	Missense_Mutation	NA	E1727K	0.25
CESC	chr12	122577736	Missense_Mutation	NA	R929T	0.36
CESC	chr12	122575862	Missense_Mutation	novel	G850A	0.23
CESC	chr12	122594375	Missense_Mutation	novel	E1449Q	0.32
CESC	chr12	122584987	Missense_Mutation	NA	M1177I	0.28
CESC	chr12	122587869	Missense_Mutation	NA	E1297K	0.55
COAD	chr12	122544166	Missense_Mutation	novel	G189E	0.26
COAD	chr12	122542097	Missense_Mutation	NA	T165A	0.37
COAD	chr12	122590647	Missense_Mutation	NA	G1347D	0.32
COAD	chr12	122605055	Missense_Mutation	NA	R1785I	0.38
COAD	chr12	122603057	Missense_Mutation	NA	A1639T	0.14
COAD	chr12	122557464	Nonsense_Mutation	novel	W451*	0.17
COAD	chr12	122568365	Missense_Mutation	rs781762358	R570Q	0.21
COAD	chr12	122605055	Missense_Mutation	NA	R1785I	0.07
COAD	chr12	122577754	Missense_Mutation	rs754831260	R935Q	0.26
COAD	chr12	122584897	Missense_Mutation	NA	F1147L	0.25
COAD	chr12	122604999	Silent	rs751686054	I1766I	0.34
COAD	chr12	122613726	Missense_Mutation	NA	K1948E	0.77
COAD	chr12	122544206	Silent	novel	H202H	0.16
COAD	chr12	122603072	Frame_Shift_Ins	NA	*L1647Tfs12**	0.3
COAD	chr12	122620641	Intron	novel		0.38
COAD	chr12	122597842	Silent	novel	R1489R	0.14
COAD	chr12	122587716	Missense_Mutation	novel	G1246C	0.09
COAD	chr12	122591403	Missense_Mutation	rs566613986	R1399C	0.33
COAD	chr12	122603153	Missense_Mutation	novel	T1671A	0.1
COAD	chr12	122571076	Frame_Shift_Ins	novel	*T659Nfs33**	0.07
COAD	chr12	122573262	Nonsense_Mutation	NA	E754*	0.43
COAD	chr12	122542100	Missense_Mutation	NA	N166Y	0.46
COAD	chr12	122546242	Missense_Mutation	NA	N246H	0.19
COAD	chr12	122585722	Missense_Mutation	novel	Q1207H	0.08
COAD	chr12	122587801	Missense_Mutation	NA	F1274C	0.15
COAD	chr12	122591396	Silent	novel	L1396L	0.21
COAD	chr12	122601559	Missense_Mutation	NA	M1529I	0.15
COAD	chr12	122620432	Intron	novel		0.13
COAD	chr12	122604881	Missense_Mutation	NA	E1727G	0.32
COAD	chr12	122605335	Missense_Mutation	rs529981688	E1806K	0.4
COAD	chr12	122620514	Missense_Mutation	NA	V2062A	0.32
COAD	chr12	122568311	Frame_Shift_Del	NA	*L554Yfs3**	0.11
COAD	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.48
COAD	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.23
COAD	chr12	122590724	Missense_Mutation	NA	D1373N	0.2
COAD	chr12	122587839	Missense_Mutation	NA	V1287M	0.09
COAD	chr12	122590641	Missense_Mutation	rs745930138	A1345V	0.31
COAD	chr12	122602688	Nonsense_Mutation	novel	*L1591_P1592insSN**	0.04
COAD	chr12	122602690	Missense_Mutation	novel	P1592H	0.01
COAD	chr12	122568278	Missense_Mutation	novel	E541A	0.06
COAD	chr12	122609389	Silent	rs534116201	P1834P	0.03
COAD	chr12	122603073	Frame_Shift_Del	novel	*K1646Tfs12**	0.13
DLBC	chr12	122622545	Silent	novel	K2151K	0.3
ESCA	chr12	122551504	Missense_Mutation	novel	E393K	0.22
ESCA	chr12	122551620	Splice_Site	novel	X399_splice	0.08
ESCA	chr12	122597803	Silent	NA	G1476G	0.13
ESCA	chr12	122572975	Missense_Mutation	novel	R686S	0.09
GBM	chr12	122622535	Missense_Mutation	novel	Q2148R	0.07
GBM	chr12	122609383	Splice_Site	novel	X1833_splice	0.32
GBM	chr12	122613651	Silent	novel	L1923L	0.48
GBM	chr12	122582800	Silent	novel	A1026A	0.35
GBM	chr12	122603029	Missense_Mutation	novel	F1629L	0.14
GBM	chr12	122610901	Splice_Site	rs752265057	X1874_splice	0.34
GBM	chr12	122613674	Missense_Mutation	novel	N1930K	0.04
HNSC	chr12	122602836	Silent	rs760590719	E1611E	0.28
HNSC	chr12	122618395	Nonsense_Mutation	novel	S2028*	0.3
HNSC	chr12	122604619	Silent	novel	L1719L	0.19
HNSC	chr12	122605308	Missense_Mutation	novel	I1797V	0.25
HNSC	chr12	122597893	Silent	rs764898553	T1506T	0.17
HNSC	chr12	122538422	Missense_Mutation	novel	H112Y	0.5
HNSC	chr12	122534732	Silent	novel	S66S	0.15
HNSC	chr12	122610857	Missense_Mutation	novel	Y1860C	0.31
HNSC	chr12	122618535	Missense_Mutation	novel	A2047T	0.27
HNSC	chr12	122605389	Silent	novel	L1824L	0.47
HNSC	chr12	122585666	Missense_Mutation	novel	E1189K	0.16
HNSC	chr12	122613181	Missense_Mutation	novel	D1898N	0.16
HNSC	chr12	122576915	Silent	NA	L869L	0.41
HNSC	chr12	122569728	Silent	novel	L588L	0.27
KIRC	chr12	122603155	Silent	rs757883690	T1671T	0.11
KIRC	chr12	122569711	Missense_Mutation	NA	M583L	0.21
KIRC	chr12	122575822	Missense_Mutation	novel	Y837N	0.32
KIRC	chr12	122579942	Missense_Mutation	novel	V960A	0.23
KIRC	chr12	122549848	Missense_Mutation	NA	Q357R	0.27
KIRC	chr12	122551354	Frame_Shift_Ins	novel	*D375Lfs14**	0.04
KIRC	chr12	122551356	In_Frame_Ins	novel	D375delinsEKKKHWEKMA	0.02
KIRP	chr12	122549777	Silent	novel	L333L	0.44
KIRP	chr12	122586741	Frame_Shift_Del	novel	*C1239Afs14**	0.11
KIRP	chr12	122590650	Frame_Shift_Del	novel	*C1349Sfs9**	0.38
KIRP	chr12	122580637	Missense_Mutation	novel	M983I	0.53
KIRP	chr12	122604615	Nonsense_Mutation	novel	W1718*	0.31
KIRP	chr12	122604616	Missense_Mutation	novel	W1718C	0.31
KIRP	chr12	122568367	Missense_Mutation	novel	H571Y	0.46
LAML	chr12	122613738	Nonsense_Mutation	novel	K1952*	0.26
LAML	chr12	122580609	Missense_Mutation	novel	L974Q	0.5
LGG	chr12	122549832	Missense_Mutation	novel	V352I	0.4
LGG	chr12	122562677	Missense_Mutation	novel	A528T	0.41
LGG	chr12	122582776	Silent	novel	Q1018Q	0.37
LGG	chr12	122582827	Silent	novel	T1035T	0.11
LIHC	chr12	122601552	Missense_Mutation	NA	Y1527C	0.13
LIHC	chr12	122621879	Splice_Site	novel	X2094_splice	0.36
LIHC	chr12	122626268	3'UTR	novel		0.13
LIHC	chr12	122570870	Splice_Site	novel	X621_splice	0.25
LIHC	chr12	122573167	Missense_Mutation	novel	R722P	0.25
LIHC	chr12	122620447	Intron	novel		0.33
LIHC	chr12	122620448	Intron	novel		0.35
LIHC	chr12	122585715	Missense_Mutation	NA	E1205V	0.44
LIHC	chr12	122571060	Missense_Mutation	NA	E651D	0.07
LUAD	chr12	122602695	Missense_Mutation	NA	H1594Y	0.21
LUAD	chr12	122620620	Intron	novel		0.38
LUAD	chr12	122602646	Missense_Mutation	novel	L1577F	0.49
LUAD	chr12	122582971	Silent	NA	A1083A	0.65
LUAD	chr12	122620543	Missense_Mutation	rs377336279	P2072S	0.17
LUAD	chr12	122585689	Missense_Mutation	NA	F1196L	0.29
LUAD	chr12	122597898	Missense_Mutation	NA	T1508K	0.07
LUAD	chr12	122569760	Missense_Mutation	novel	K599T	0.06
LUAD	chr12	122602875	Silent	NA	S1624S	0.11
LUAD	chr12	122557419	Missense_Mutation	NA	E436D	0.34
LUAD	chr12	122582714	Missense_Mutation	novel	E998Q	0.35
LUAD	chr12	122582846	Missense_Mutation	novel	E1042K	0.22
LUAD	chr12	122618514	Missense_Mutation	NA	D2040Y	0.18
LUAD	chr12	122605048	Missense_Mutation	NA	N1783H	0.5
LUAD	chr12	122587710	Splice_Site	NA	X1244_splice	0.62
LUAD	chr12	122590673	Missense_Mutation	novel	D1356Y	0.24
LUAD	chr12	122603075	Nonsense_Mutation	novel	K1645*	0.21
LUAD	chr12	122530077	Missense_Mutation	rs556183893	I5T	0.23
LUAD	chr12	122562646	Missense_Mutation	novel	R517S	0.38
LUAD	chr12	122604877	Missense_Mutation	rs772711216	D1726Y	0.3
LUAD	chr12	122557649	Missense_Mutation	novel	Y483C	0.47
LUAD	chr12	122597840	Missense_Mutation	rs201757501	R1489W	0.6
LUAD	chr12	122530040	5'UTR	novel		0.32
LUAD	chr12	122602722	Missense_Mutation	NA	N1603H	0.17
LUSC	chr12	122615016	Missense_Mutation	NA	C1968Y	0.26
LUSC	chr12	122618347	Missense_Mutation	novel	P2012L	0.23
LUSC	chr12	122569788	Silent	novel	V608V	0.15
LUSC	chr12	122597873	Nonsense_Mutation	novel	E1500*	0.3
LUSC	chr12	122604590	Missense_Mutation	NA	F1710L	0.23
LUSC	chr12	122534731	Missense_Mutation	novel	S66L	0.28
LUSC	chr12	122610837	Silent	novel	L1853L	0.14
LUSC	chr12	122575558	Missense_Mutation	novel	V800L	0.38
LUSC	chr12	122551498	Missense_Mutation	novel	L391V	0.21
LUSC	chr12	122574293	Silent	rs768380870	N765N	0.35
LUSC	chr12	122569818	Silent	novel	E618E	0.2
LUSC	chr12	122587709	Splice_Site	rs753300288	X1244_splice	0.33
LUSC	chr12	122620629	Intron	novel		0.17
LUSC	chr12	122557455	Missense_Mutation	NA	Q448H	0.27
LUSC	chr12	122557482	Silent	rs201683456	D457D	0.08
LUSC	chr12	122597923	Silent	novel	S1516S	0.54
LUSC	chr12	122582883	Missense_Mutation	novel	R1054K	0.33
LUSC	chr12	122605374	Silent	novel	L1819L	0.3
LUSC	chr12	122620603	Missense_Mutation	novel	I2092V	0.13
LUSC	chr12	122622497	Missense_Mutation	novel	K2135N	0.5
LUSC	chr12	122584436	Missense_Mutation	novel	T1141S	0.09
LUSC	chr12	122562697	Splice_Region	NA	F534F	0.14
OV	chr12	122577749	Frame_Shift_Ins	novel	*A934Lfs16**	0.04
OV	chr12	122573210	Silent	NA	I736I	0.38
OV	chr12	122575800	Frame_Shift_Del	novel	*K831Tfs3**	0.29
OV	chr12	122569685	Missense_Mutation	novel	N574I	0.07
OV	chr12	122530102	Silent	rs763877172	T13T	0.18
OV	chr12	122568272	Missense_Mutation	rs199501312	W539L	0.19
OV	chr12	122603218	Silent	NA	I1692I	0.38
OV	chr12	122557455	Missense_Mutation	NA	Q448H	0.29
OV	chr12	122534731	Nonsense_Mutation	novel	S66*	0.1
OV	chr12	122573199	Missense_Mutation	novel	I733V	0.05
OV	chr12	122577764	Frame_Shift_Del	novel	*Q939Gfs17**	0.35
PAAD	chr12	122587814	Silent	novel	S1278S	0.16
PAAD	chr12	122597779	Silent	rs548835839	T1468T	0.22
PRAD	chr12	122574378	Missense_Mutation	novel	D794N	0.26
PRAD	chr12	122575896	Missense_Mutation	novel	I861M	0.43
READ	chr12	122615502	Missense_Mutation	NA	I2002M	0.05
READ	chr12	122574324	Nonsense_Mutation	NA	E776*	0.59
READ	chr12	122613753	Missense_Mutation	rs759532010	E1957K	0.53
READ	chr12	122622554	Silent	rs538519234	A2154A	0.53
READ	chr12	122626394	3'UTR	novel		0.67
READ	chr12	122547928	Missense_Mutation	novel	N316H	0.1
SARC	chr12	122551465	Missense_Mutation	novel	E380K	0.23
SARC	chr12	122585644	Silent	rs546067080	F1181F	0.4
SARC	chr12	122575588	Missense_Mutation	rs151068294	P810S	0.22
SARC	chr12	122530123	Silent	rs370631854	V20V	0.3
SARC	chr12	122557475	Missense_Mutation	novel	V455A	0.11
SARC	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.34
SKCM	chr12	122588765	Missense_Mutation	NA	K1316N	0.46
SKCM	chr12	122613758	Silent	NA	S1958S	0.4
SKCM	chr12	122586712	Frame_Shift_Del	novel	*Y1229Cfs17**	0.23
SKCM	chr12	122575556	Missense_Mutation	NA	A799V	0.56
SKCM	chr12	122594320	Silent	NA	K1430K	0.18
SKCM	chr12	122602874	Missense_Mutation	rs763188648	S1624L	0.11
SKCM	chr12	122582792	Missense_Mutation	rs760669670	E1024K	0.15
SKCM	chr12	122618346	Missense_Mutation	NA	P2012S	0.14
SKCM	chr12	122549775	Missense_Mutation	NA	L333F	0.25
SKCM	chr12	122584392	Silent	NA	L1126L	0.24
SKCM	chr12	122544178	Missense_Mutation	NA	S193F	0.4
SKCM	chr12	122610838	Silent	rs190394641	L1854L	0.21
SKCM	chr12	122613213	Missense_Mutation	NA	K1908N	0.5
SKCM	chr12	122618346	Missense_Mutation	NA	P2012S	0.3
SKCM	chr12	122585754	Missense_Mutation	NA	S1218L	0.22
SKCM	chr12	122571123	Silent	NA	S672S	0.18
SKCM	chr12	122604944	Missense_Mutation	NA	T1748R	0.7
SKCM	chr12	122602695	Missense_Mutation	NA	H1594Y	0.18
SKCM	chr12	122546219	Missense_Mutation	NA	S238C	0.1
SKCM	chr12	122610819	Splice_Region	novel		0.44
SKCM	chr12	122613677	Silent	novel	I1931I	0.61
STAD	chr12	122534689	Missense_Mutation	NA	A52V	0.33
STAD	chr12	122575577	Missense_Mutation	rs757801099	A806V	0.2
STAD	chr12	122584969	Silent	novel	D1171D	0.11
STAD	chr12	122575573	Missense_Mutation	NA	Y805H	0.24
STAD	chr12	122603176	Silent	NA	L1678L	0.24
STAD	chr12	122626240	3'UTR	rs760503972		0.26
STAD	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.38
STAD	chr12	122588716	Missense_Mutation	NA	F1300S	0.5
STAD	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.38
STAD	chr12	122568311	Frame_Shift_Del	NA	*L554Yfs3**	0.33
STAD	chr12	122591437	Missense_Mutation	NA	R1410H	0.33
STAD	chr12	122613212	Missense_Mutation	NA	K1908T	0.38
STAD	chr12	122568328	Missense_Mutation	novel	E558K	0.31
STAD	chr12	122615074	Silent	NA	L1987L	0.35
STAD	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.36
STAD	chr12	122584449	Splice_Region	NA	P1145P	0.47
STAD	chr12	122603179	Silent	NA	L1679L	0.3
STAD	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.44
STAD	chr12	122597773	Silent	NA	I1466I	0.12
STAD	chr12	122568311	Frame_Shift_Del	NA	*L554Yfs3**	0.07
STAD	chr12	122570894	Silent	NA	L627L	0.25
STAD	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.38
STAD	chr12	122568311	Frame_Shift_Del	NA	*L554Yfs3**	0.3
STAD	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.42
STAD	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.22
STAD	chr12	122568311	Frame_Shift_Del	NA	*L554Yfs3**	0.24
STAD	chr12	122590611	Frame_Shift_Del	novel	*N1336Vfs4**	0.03
STAD	chr12	122620544	Missense_Mutation	rs370269719	P2072L	0.13
STAD	chr12	122575635	Missense_Mutation	NA	M825I	0.47
STAD	chr12	122615055	Missense_Mutation	NA	G1981E	0.18
STAD	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.25
TGCT	chr12	122557423	Missense_Mutation	novel	L438V	0.24
TGCT	chr12	122572936	Splice_Site	rs779604603	X674_splice	0.31
TGCT	chr12	122622491	Missense_Mutation	novel	I2133M	0.1
UCEC	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.12
UCEC	chr12	122594312	Missense_Mutation	novel	T1428A	0.14
UCEC	chr12	122620576	Missense_Mutation	rs756158800	P2083S	0.31
UCEC	chr12	122626227	Silent	novel	*2210*	0.14
UCEC	chr12	122620468	Intron	novel		0.36
UCEC	chr12	122562639	Missense_Mutation	novel	V515A	0.3
UCEC	chr12	122568365	Missense_Mutation	rs781762358	R570Q	0.09
UCEC	chr12	122602737	Missense_Mutation	rs755131976	L1608I	0.44
UCEC	chr12	122610842	Missense_Mutation	rs374343598	S1855F	0.27
UCEC	chr12	122571088	Missense_Mutation	rs765751440	E661K	0.41
UCEC	chr12	122602737	Missense_Mutation	rs755131976	L1608I	0.32
UCEC	chr12	122622491	Silent	NA	I2133I	0.14
UCEC	chr12	122546645	Missense_Mutation	novel	D263N	0.37
UCEC	chr12	122582765	Missense_Mutation	novel	L1015I	0.33
UCEC	chr12	122613226	Missense_Mutation	novel	V1913M	0.31
UCEC	chr12	122620658	Intron	novel		0.4
UCEC	chr12	122587767	Missense_Mutation	rs748027315	Q1263E	0.05
UCEC	chr12	122602691	Frame_Shift_Del	novel	*H1594Tfs2**	0.22
UCEC	chr12	122602717	Missense_Mutation	NA	A1601V	0.43
UCEC	chr12	122609427	Missense_Mutation	rs202054994	R1847Q	0.47
UCEC	chr12	122620291	Intron	novel		0.5
UCEC	chr12	122620592	Missense_Mutation	NA	R2088I	0.16
UCEC	chr12	122585655	Missense_Mutation	novel	K1185T	0.51
UCEC	chr12	122575557	Silent	rs765314103	A799A	0.41
UCEC	chr12	122576899	Missense_Mutation	novel	V864G	0.51
UCEC	chr12	122588746	Missense_Mutation	novel	H1310R	0.18
UCEC	chr12	122597844	Missense_Mutation	rs746207263	R1490Q	0.47
UCEC	chr12	122601550	Missense_Mutation	novel	D1526E	0.36
UCEC	chr12	122561921	Missense_Mutation	novel	L497F	0.35
UCEC	chr12	122582940	Missense_Mutation	novel	R1073I	0.36
UCEC	chr12	122590690	Silent	novel	L1361L	0.47
UCEC	chr12	122539720	Missense_Mutation	novel	Q137H	0.13
UCEC	chr12	122568277	Missense_Mutation	novel	E541K	0.2
UCEC	chr12	122602737	Missense_Mutation	rs755131976	L1608I	0.23
UCEC	chr12	122585735	Missense_Mutation	rs777382168	V1212M	0.26
UCEC	chr12	122604879	Splice_Region	NA	D1726D	0.42
UCEC	chr12	122530187	Frame_Shift_Ins	novel	*A44Gfs14**	0.47
UCEC	chr12	122549831	Silent	NA	S351S	0.46
UCEC	chr12	122622502	Missense_Mutation	NA	E2137G	0.44
UCEC	chr12	122603165	Missense_Mutation	novel	E1675K	0.33
UCEC	chr12	122577700	Missense_Mutation	NA	S917Y	0.27
UCEC	chr12	122579924	Missense_Mutation	NA	S954Y	0.13
UCEC	chr12	122621942	Missense_Mutation	rs771390477	T2114M	0.25
UCEC	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.48
UCEC	chr12	122575577	Missense_Mutation	rs757801099	A806V	0.27
UCEC	chr12	122624643	Silent	rs559434593	C2187C	0.25
UCEC	chr12	122575853	Missense_Mutation	rs769739544	R847Q	0.26
UCEC	chr12	122590688	Missense_Mutation	NA	L1361I	0.46
UCEC	chr12	122577031	Splice_Site	novel	X907_splice	0.43
UCEC	chr12	122585684	Missense_Mutation	novel	D1195Y	0.16
UCEC	chr12	122588723	Silent	novel	E1302E	0.21
UCEC	chr12	122602846	Nonsense_Mutation	novel	E1615*	0.41
UCEC	chr12	122620592	Missense_Mutation	NA	R2088I	0.5
UCEC	chr12	122575852	Nonsense_Mutation	rs745858002	R847*	0.43
UCEC	chr12	122579948	Missense_Mutation	novel	I962T	0.18
UCEC	chr12	122618535	Missense_Mutation	novel	A2047T	0.24
UCEC	chr12	122605055	Missense_Mutation	NA	R1785I	0.63
UCEC	chr12	122580623	Missense_Mutation	rs201575472	E979K	0.46
UCEC	chr12	122604634	Silent	rs770373434	S1724S	0.38
UCEC	chr12	122534688	Missense_Mutation	novel	A52T	0.36
UCEC	chr12	122568311	Frame_Shift_Del	NA	*L554Yfs3**	0.51
UCEC	chr12	122575578	Silent	novel	A806A	0.51
UCEC	chr12	122597798	Missense_Mutation	novel	A1475T	0.52
UCEC	chr12	122601544	Silent	novel	P1524P	0.38
UCEC	chr12	122597803	Silent	NA	G1476G	0.36
UCEC	chr12	122539675	Splice_Site	novel	X123_splice	0.56
UCEC	chr12	122602581	Missense_Mutation	novel	L1556M	0.37
UCEC	chr12	122604567	Missense_Mutation	novel	S1702F	0.37
UCEC	chr12	122613657	Missense_Mutation	novel	S1925P	0.26
UCEC	chr12	122569819	Nonsense_Mutation	novel	G619*	0.13
UCEC	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.44
UCEC	chr12	122584360	Missense_Mutation	NA	D1116N	0.37
UCEC	chr12	122584970	Missense_Mutation	NA	D1172N	0.45
UCEC	chr12	122577779	Missense_Mutation	NA	D943E	0.5
UCEC	chr12	122613738	Frame_Shift_Del	novel	*N1953Tfs9**	0.4
UCEC	chr12	122530122	Missense_Mutation	NA	V20A	0.18
UCEC	chr12	122584341	Silent	novel	K1109K	0.06
UCEC	chr12	122587713	Missense_Mutation	NA	D1245Y	0.37
UCEC	chr12	122620665	Intron	novel		0.14
UCEC	chr12	122588727	Missense_Mutation	novel	T1304A	0.41
UCEC	chr12	122605326	Nonsense_Mutation	novel	E1803*	0.21
UCEC	chr12	122626263	3'UTR	novel		0.5
UCEC	chr12	122551321	Splice_Region	novel	D363D	0.15
UCEC	chr12	122582971	Silent	NA	A1083A	0.28
UCEC	chr12	122621942	Missense_Mutation	rs771390477	T2114M	0.32
UCEC	chr12	122624623	Missense_Mutation	novel	T2181A	0.31
UCEC	chr12	122572995	Missense_Mutation	rs772245787	R693Q	0.3
UCEC	chr12	122594280	Missense_Mutation	rs745665785	S1417Y	0.07
UCEC	chr12	122621944	Missense_Mutation	novel	G2115S	0.17
UCEC	chr12	122618362	Missense_Mutation	rs748143502	A2017V	0.4
UCEC	chr12	122622553	Missense_Mutation	rs760448774	A2154V	0.54
UCEC	chr12	122551627	Silent	rs370532690	S401S	0.41
UCEC	chr12	122587798	Missense_Mutation	novel	R1273I	0.26
UCEC	chr12	122530163	Missense_Mutation	novel	D34Y	0.38
UCEC	chr12	122574373	Missense_Mutation	novel	D792G	0.42
UCEC	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.46
UCEC	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.36
UCEC	chr12	122546216	Missense_Mutation	NA	S237Y	0.18
UCEC	chr12	122571060	Missense_Mutation	NA	E651D	0.4
UCEC	chr12	122539706	Missense_Mutation	rs775527571	R133W	0.19
UCEC	chr12	122549810	Silent	novel	L344L	0.14
UCEC	chr12	122602838	Missense_Mutation	novel	L1612P	0.18
UCEC	chr12	122547528	Splice_Region	novel	T310T	0.54
UCEC	chr12	122597843	Missense_Mutation	rs369923772	R1490W	0.13
UCEC	chr12	122575557	Silent	rs765314103	A799A	0.38
UCEC	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.2
UCEC	chr12	122568311	Frame_Shift_Del	NA	*L554Yfs3**	0.24
UCEC	chr12	122604962	Missense_Mutation	NA	A1754V	0.2
UCEC	chr12	122542121	Missense_Mutation	NA	Q173K	0.46
UCEC	chr12	122571060	Missense_Mutation	NA	E651D	0.46
UCEC	chr12	122586710	Missense_Mutation	NA	R1228I	0.43
UCEC	chr12	122590619	Missense_Mutation	rs752336311	R1338C	0.4
UCEC	chr12	122620291	Intron	novel		0.73
UCEC	chr12	122577001	Missense_Mutation	novel	R898I	0.03
UCEC	chr12	122603073	Frame_Shift_Del	NA	*K1646Nfs2**	0.47
UCEC	chr12	122568310	Frame_Shift_Ins	novel	*L554Ffs23**	0.47
UCEC	chr12	122557634	Missense_Mutation	rs778452685	A478D	0.12
UCEC	chr12	122568285	Silent	rs374104707	L543L	0.29
UCEC	chr12	122569708	Missense_Mutation	novel	K582Q	0.18
UCEC	chr12	122605020	Silent	novel	I1773I	0.22
UCEC	chr12	122610828	Silent	rs370414071	Q1850Q	0.14
UCEC	chr12	122615047	Silent	novel	L1978L	0.2
UCEC	chr12	122575553	Missense_Mutation	novel	D798V	0.38
UCEC	chr12	122621894	Missense_Mutation	novel	S2098F	0.43
UCEC	chr12	122597745	Missense_Mutation	NA	D1457G	0.29
UCEC	chr12	122584341	Silent	novel	K1109K	0.45
UCEC	chr12	122584893	Frame_Shift_Ins	novel	*L1148Ffs9**	0.43
UCEC	chr12	122577684	Missense_Mutation	novel	L912F	0.34
UCEC	chr12	122587875	Splice_Site	novel	X1298_splice	0.41
UCEC	chr12	122620466	Intron	novel		0.51
UCS	chr12	122582793	Missense_Mutation	novel	E1024G	0.41
UCS	chr12	122602737	Missense_Mutation	rs755131976	L1608I	0.28

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BRCA	DEL	0.1611	6.3933e-07
CHOL	DEL	0.1944	0.067545
HNSC	DEL	0.0556	0.22646
LIHC	DEL	0.1189	2.3723e-05
LUAD	DEL	0.1453	0.0059643
LUSC	DEL	0.1098	0.038823
PAAD	DEL	0.1685	0.0030251
PRAD	AMP	0.0427	0.016187
SKCM	DEL	0.1853	0.00079981
UCEC	DEL	0.0928	0.00053229
UCS	DEL	0.3214	0.033261

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0021	Kaplan-Meier Survival Analysis
KIRC	0.0001	Kaplan-Meier Survival Analysis
STAD	0.019	Kaplan-Meier Survival Analysis
SARC	0.0015	Kaplan-Meier Survival Analysis
MESO	0.00022	Kaplan-Meier Survival Analysis
ACC	0.00012	Kaplan-Meier Survival Analysis
UCS	0.017	Kaplan-Meier Survival Analysis
PRAD	0.03	Kaplan-Meier Survival Analysis
LUSC	0.03	Kaplan-Meier Survival Analysis
KIRP	0.0015	Kaplan-Meier Survival Analysis
PAAD	0.045	Kaplan-Meier Survival Analysis
PCPG	0.013	Kaplan-Meier Survival Analysis
CESC	0.009	Kaplan-Meier Survival Analysis
READ	0.035	Kaplan-Meier Survival Analysis
KICH	0.0009	Kaplan-Meier Survival Analysis
UCEC	0.0089	Kaplan-Meier Survival Analysis
LIHC	0.00013	Kaplan-Meier Survival Analysis
LUAD	0.01	Kaplan-Meier Survival Analysis
UVM	0.028	Kaplan-Meier Survival Analysis
OV	0.0092	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Phenotype

GWAS

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000184445 (Gene tree)
Gene ID: 9735
Gene Symbol: KNTC1
Alias: KIAA0166|ROD
Full Name: kinetochore associated 1
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Plus strand
Length: 100,066 bases
Position: chr12:122,527,246-122,627,311
Accession: 17255
Summary: This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. Experimental evidence indicated that the encoded protein functioned in a similar manner to that of the Drosophila rough deal protein. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000333479	KNTC1-201	6975	XM_006719706	ENSP00000328236	2209 (aa)	XP_006719769	P50748
ENST00000377192	KNTC1-202	1519	-	-	- (aa)	-	-
ENST00000450485	KNTC1-205	3655	-	ENSP00000397992	1134 (aa)	-	E7ES84
ENST00000546125	KNTC1-215	624	-	ENSP00000439119	208 (aa)	-	H0YFL5
ENST00000541427	KNTC1-211	641	-	-	- (aa)	-	-
ENST00000423927	KNTC1-203	1250	-	ENSP00000397140	104 (aa)	-	J3KQF2
ENST00000539013	KNTC1-210	615	-	-	- (aa)	-	-
ENST00000536625	KNTC1-209	1178	-	-	- (aa)	-	-
ENST00000436959	KNTC1-204	2412	-	ENSP00000408760	130 (aa)	-	F5H5V0
ENST00000534995	KNTC1-206	1065	-	ENSP00000437344	130 (aa)	-	F5H5V0
ENST00000541466	KNTC1-212	616	-	-	- (aa)	-	-
ENST00000542727	KNTC1-213	203	-	-	- (aa)	-	-
ENST00000545065	KNTC1-214	782	-	-	- (aa)	-	-
ENST00000535410	KNTC1-208	331	-	-	- (aa)	-	-
ENST00000535186	KNTC1-207	553	-	-	- (aa)	-	-

Gene Model

Click here to download 's gene model file

Phenotype

ensgID	Trait	pValue	Pubmed ID
ENSG00000184445	Platelet Function Tests	1.1536500E-005	-
ENSG00000184445	Platelet Function Tests	1.5662700E-005	-
ENSG00000184445	Adiponectin	4E-6	22479202

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000184445	rs4319547	12	122594488	G	Body mass index	28892062	[0.01-0.022] kg/m2 increase	0.016	EFO_0004340
ENSG00000184445	rs10734924	12	122534347	T	Educational attainment (MTAG)	30038396	[0.0073-0.0131] unit decrease	0.0102	EFO_0004784
ENSG00000184445	rs10734924	12	122534347	T	Highest math class taken (MTAG)	30038396	[0.0079-0.0153] unit decrease	0.0116	EFO_0004875
ENSG00000184445	rs36117464	12	122585671	A	Cognitive performance (MTAG)	30038396	[0.02-0.043] unit increase	0.0314	EFO_0008354
ENSG00000184445	rs147730268	12	122539929	T	Hand grip strength	29691431	[0.002-0.004] unit increase	0.003	EFO_0006941
ENSG00000184445	rs4319547	12	122594488	A	Body mass index	30108127	[NR] unit decrease	0.015	EFO_0004340
ENSG00000184445	rs147730268	12	122539929	?	Body mass index	30595370			EFO_0004340
ENSG00000184445	rs6489111	12	122566471	G	Body fat distribution (leg fat ratio)	30664634	NR unit decrease (replication)	0.01068	EFO_0004341
ENSG00000184445	rs6489111	12	122566471	G	Body fat distribution (trunk fat ratio)	30664634	NR unit increase (replication)	0.01512	EFO_0004341
ENSG00000184445	rs6489111	12	122566471	G	Body fat distribution (leg fat ratio)	30664634	NR unit decrease (replication)	0.01874	EFO_0004341

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000184445's network

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000777	condensed chromosome kinetochore	-	IEA	Component
GO:0000922	spindle pole	11146660.	IDA	Component
GO:0005515	protein binding	11146660.12686595.19468067.20462495.	IPI	Function
GO:0005634	nucleus	11146660.	NAS	Component
GO:0005828	kinetochore microtubule	11146660.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005886	plasma membrane	-	IDA	Component
GO:0007093	mitotic cell cycle checkpoint	11146660.	IDA	Process
GO:0007096	regulation of exit from mitosis	11146660.	NAS	Process
GO:0015629	actin cytoskeleton	-	IDA	Component
GO:0051301	cell division	-	IEA	Process
GO:0065003	protein-containing complex assembly	11146660.	NAS	Process
GO:1990423	RZZ complex	20462495.	IDA	Component

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Phenotype

GWAS

PPI

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.