EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr17	81890721	Missense_Mutation	novel	L120V	0.04	RRM_1
BLCA	chr17	81889224	Missense_Mutation	rs777282962	A166T	0.5	RRM_1
BLCA	chr17	81888299	Missense_Mutation	novel	S241L	0.42
BLCA	chr17	81888380	Missense_Mutation	NA	G214A	0.35
BLCA	chr17	81889192	Silent	novel	V176V	0.11
BLCA	chr17	81890705	Nonsense_Mutation	novel	S125*	0.1	RRM_1
BLCA	chr17	81890691	Nonsense_Mutation	novel	Q130*	0.24	RRM_1
BLCA	chr17	81888362	Missense_Mutation	rs752276341	G220A	0.24
BLCA	chr17	81890703	Missense_Mutation	novel	D126H	0.14	RRM_1
BLCA	chr17	81888535	Missense_Mutation	novel	R196Q	0.21
BLCA	chr17	81889319	Missense_Mutation	novel	A134D	0.09	RRM_1
BLCA	chr17	81890691	Nonsense_Mutation	novel	Q130*	0.15	RRM_1
BLCA	chr17	81889251	Missense_Mutation	novel	D157H	0.21	RRM_1
BRCA	chr17	81889223	In_Frame_Ins	novel	D165dup	0.63	RRM_1
CESC	chr17	81887843	3'Flank	novel		0.6
COAD	chr17	81889194	Missense_Mutation	novel	V176I	0.31	RRM_1
COAD	chr17	81888071	3'UTR	novel		0.63
COAD	chr17	81889185	Missense_Mutation	NA	D179H	0.28	RRM_1
ESCA	chr17	81887925	3'UTR	novel		0.09
HNSC	chr17	81888311	Missense_Mutation	novel	A237V	0.55
HNSC	chr17	81888146	Splice_Site	novel	X261_splice	0.16
HNSC	chr17	81889306	Silent	novel	T138T	0.76
KIRC	chr17	81888404	Missense_Mutation	novel	G206V	0.55
KIRC	chr17	81888531	Missense_Mutation	NA	R197S	0.16
LGG	chr17	81888048	3'UTR	novel		0.11
LIHC	chr17	81890719	Silent	rs759837859	L120L	0.5
LIHC	chr17	81888354	Silent	novel	R223R	0.09
LUAD	chr17	81889234	Silent	novel	R162R	0.16
LUAD	chr17	81888306	Silent	novel	R239R	0.23
LUSC	chr17	81888324	Missense_Mutation	NA	R233G	0.41
LUSC	chr17	81888366	Missense_Mutation	rs769045326	G219S	0.13
OV	chr17	81889258	Silent	novel	G154G	0.04
PRAD	chr17	81889251	Missense_Mutation	novel	D157N	0.45	RRM_1
READ	chr17	81888309	Missense_Mutation	NA	G238S	0.79
SARC	chr17	81888079	3'UTR	novel		0.47
SKCM	chr17	81888115	3'UTR	rs763559518		0.26
SKCM	chr17	81888304	Silent	rs765953765	R239R	0.27
SKCM	chr17	81889278	Missense_Mutation	NA	R148C	0.4	RRM_1
STAD	chr17	81888245	Missense_Mutation	NA	A259G	0.4
UCEC	chr17	81889295	Missense_Mutation	NA	A142V	0.48	RRM_1
UCEC	chr17	81888536	Missense_Mutation	rs781729860	R196W	0.19
UCEC	chr17	81887931	3'UTR	novel		0.5
UCEC	chr17	81890726	Missense_Mutation	novel	S118F	0.38	RRM_1
UCEC	chr17	81889306	Silent	novel	T138T	0.2
UCEC	chr17	81888093	3'UTR	novel		0.38
UCEC	chr17	81889292	Missense_Mutation	novel	A143V	0.13	RRM_1
UCEC	chr17	81888295	Missense_Mutation	novel	K242N	0.29
UCEC	chr17	81888113	3'UTR	rs759827154		0.34
UCEC	chr17	81889223	Missense_Mutation	NA	A166V	0.69	RRM_1
UCEC	chr17	81888256	Silent	rs749604246	D255D	0.48
UCEC	chr17	81888547	Missense_Mutation	novel	I192S	0.48
UCEC	chr17	81889248	Missense_Mutation	NA	V158M	0.32	RRM_1
UCEC	chr17	81889216	Missense_Mutation	NA	K168N	0.46	RRM_1
UCEC	chr17	81888018	3'UTR	novel		0.5
UCEC	chr17	81888389	Missense_Mutation	rs766163313	R211H	0.35
UCEC	chr17	81888116	3'UTR	novel		0.42
UCEC	chr17	81890728	Silent	NA	V117V	0.17

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.3897	0.00012456
CESC	DEL	0.1051	0.00067839
KIRP	AMP	0.6701	0.14801
LGG	AMP	0.0682	1.52e-05
SARC	AMP	0.1984	0.032181
SKCM	AMP	0.2834	7.0388e-08
THCA	DEL	0.002	0.221
UVM	AMP	0.1625	0.054583

Survival Analysis

Cancer	P-value	Q-value
THYM	0.026	Kaplan-Meier Survival Analysis
KIRC	0.029	Kaplan-Meier Survival Analysis
STAD	0.024	Kaplan-Meier Survival Analysis
MESO	0.021	Kaplan-Meier Survival Analysis
ACC	0.00042	Kaplan-Meier Survival Analysis
ESCA	0.014	Kaplan-Meier Survival Analysis
KIRP	0.0012	Kaplan-Meier Survival Analysis
COAD	0.017	Kaplan-Meier Survival Analysis
BLCA	0.025	Kaplan-Meier Survival Analysis
CESC	0.0077	Kaplan-Meier Survival Analysis
UCEC	0.0036	Kaplan-Meier Survival Analysis
LIHC	0.00012	Kaplan-Meier Survival Analysis
DLBC	0.026	Kaplan-Meier Survival Analysis
LGG	0.0086	Kaplan-Meier Survival Analysis
LUAD	0.011	Kaplan-Meier Survival Analysis
UVM	0.031	Kaplan-Meier Survival Analysis
OV	0.00099	Kaplan-Meier Survival Analysis

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathway

PPI

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000183684 (Gene tree)
Gene ID: 10189
Gene Symbol: ALYREF
Alias: ALY|BEF|ALY/REF|REF|THOC4
Full Name: Aly/REF export factor
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Minus strand
Length: 3,788 bases
Position: chr17:81,887,835-81,891,622
Accession: 19071
Summary: The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000421592	RRM_1	PF00076.22	4.9e-13	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	polyT & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	PolyT & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
18364396	Mutually exclusive interactions drive handover of mRNA from export adaptors to TAP.	Proc Natl Acad Sci U S A	2008 Apr 1	Hautbergue GM	doi: 10.1073/pnas.0709167105
22893130	TREX exposes the RNA-binding domain of Nxf1 to enable mRNA export.	Nat Commun	2012	Viphakone N	doi: 10.1038/ncomms2005.
19609631	Bortezomib induces the formation of nuclear poly(A) RNA granules enriched in Sam68 and PABPN1 in sensory ganglia neurons.	Neurotox Res	2010 Feb	Casafont I	doi: 10.1007/s12640-009-9086-1
20129943	Arginine methylation of REF/ALY promotes efficient handover of mRNA to TAP/NXF1.	Nucleic Acids Res	2010 Jun	Hung ML	doi: 10.1093/nar/gkq033
17609285	Kaposi's sarcoma-associated herpesvirus ORF57 protein enhances mRNA accumulation independently of effects on nuclear RNA export.	J Virol	2007 Sep	Nekorchuk M	-
22761374	Binding of cellular export factor REF/Aly by Kaposi's sarcoma-associated herpesvirus (KSHV) ORF57 protein is not required for efficient KSHV lytic replication.	J Virol	2012 Sep	Li DJ	doi: 10.1128/JVI.01190-12
21329510	Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers.	BMC Cancer	2011 Feb 17	Dominguez-Sanchez MS	doi: 10.1186/1471-2407-11-77.
16769980	Genomic localization of RNA binding proteins reveals links between pre-mRNA processing and transcription.	Genome Res	2006 Jul	Swinburne IA	-
28990926	IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs.	Elife	2017 Oct 9	Zhou H	doi: 10.7554/eLife.29630.
12809490	Structure of the nuclear factor ALY: insights into post-transcriptional regulatory and mRNA nuclear export processes.	Biochemistry	2003 Jun 24	Perez-Alvarado GC	-
12667464	SR splicing factors serve as adapter proteins for TAP-dependent mRNA export.	Mol Cell	2003 Mar	Huang Y	-
11158589	REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus.	Proc Natl Acad Sci U S A	2001 Jan 30	Rodrigues JP	-
15299117	Relocalization of nuclear ALY proteins to the cytoplasm by the tomato bushy stunt virus P19 pathogenicity protein.	Plant Physiol	2004 Aug	Uhrig JF	-
19106628	Nuclear phosphoinositide signaling regulates messenger RNA export.	RNA Biol	2009 Jan-Mar	Okada M	-
16971461	Zfp206 regulates ES cell gene expression and differentiation.	Nucleic Acids Res	2006	Zhang W	-
25662211	Luzp4 defines a new mRNA export pathway in cancer cells.	Nucleic Acids Res	2015 Feb 27	Viphakone N	doi: 10.1093/nar/gkv070
24550725	Competitive and cooperative interactions mediate RNA transfer from herpesvirus saimiri ORF57 to the mammalian export adaptor ALYREF.	PLoS Pathog	2014 Feb 13	Tunnicliffe RB	doi: 10.1371/journal.ppat.1003907
26773052	A short conserved motif in ALYREF directs cap- and EJC-dependent assembly of export complexes on spliced mRNAs.	Nucleic Acids Res	2016 Mar 18	Gromadzka AM	doi: 10.1093/nar/gkw009
28418038	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m5C reader.	Cell Res	2017 May	Yang X	doi: 10.1038/cr.2017.55
29540591	ALY RNA-Binding Proteins Are Required for Nucleocytosolic mRNA Transport and Modulate Plant Growth and Development.	Plant Physiol	2018 May	Pfaff C	doi: 10.1104/pp.18.00173
29728564	Nuclear egress of TDP-43 and FUS occurs independently of Exportin-1/CRM1.	Sci Rep	2018 May 4	Ederle H	doi: 10.1038/s41598-018-25007-5.
29941967	Accumulation of poly(A) RNA in nuclear granules enriched in Sam68 in motor neurons from the SMNdelta7 mouse model of SMA.	Sci Rep	2018 Jun 25	Narcis JO	doi: 10.1038/s41598-018-27821-3.
30858280	ALYREF links 3'-end processing to nuclear export of non-polyadenylated mRNAs.	EMBO J	2019 May 2	Fan J	doi: 10.15252/embj.201899910
21402597	Cellular cap-binding proteins associate with influenza virus mRNAs.	J Gen Virol	2011 Jul	Bier K	doi: 10.1099/vir.0.029231-0
18255312	Nuclear compartmentalization and dynamics of the poly(A)-binding protein nuclear 1 (PABPN1) inclusions in supraoptic neurons under physiological and osmotic stress conditions.	Mol Cell Neurosci	2008 Mar	Villagra NT	doi: 10.1016/j.mcn.2007.12.012
17984224	ATP-dependent recruitment of export factor Aly/REF onto intronless mRNAs by RNA helicase UAP56.	Mol Cell Biol	2008 Jan	Taniguchi I	-
24073193	Highly pathogenic avian influenza virus nucleoprotein interacts with TREX complex adaptor protein Aly/REF.	PLoS One	2013 Sep 20	Balasubramaniam VR	doi: 10.1371/journal.pone.0072429
28801509	Exosome cofactor hMTR4 competes with export adaptor ALYREF to ensure balanced nuclear RNA pools for degradation and export.	EMBO J	2017 Oct 2	Fan J	doi: 10.15252/embj.201696139

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000511412	ALYREF-203	533	-	-	- (aa)	-	-
ENST00000505490	ALYREF-202	1088	-	ENSP00000421592	264 (aa)	-	E9PB61
ENST00000504015	ALYREF-201	254	-	-	- (aa)	-	-
ENST00000512673	ALYREF-204	441	-	-	- (aa)	-	-

Gene Model

Click here to download 's gene model file

Pathway

Pathway ID	Pathway Name	Source
hsa03013	RNA transport	KEGG
hsa03015	mRNA surveillance pathway	KEGG
hsa03040	Spliceosome	KEGG
hsa05168	Herpes simplex virus 1 infection	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000183684's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000183684	ALYREF	97	67.986	ENSAPOG00000018455	ALYREF	100	71.942	Acanthochromis_polyacanthus
ENSG00000183684	ALYREF	78	85.714	ENSAMEG00000017463	ALYREF	74	91.304	Ailuropoda_melanoleuca
ENSG00000183684	ALYREF	97	75.573	ENSACAG00000010526	ALYREF	100	73.664	Anolis_carolinensis
ENSG00000183684	ALYREF	67	97.175	ENSANAG00000022638	-	75	97.175	Aotus_nancymaae
ENSG00000183684	ALYREF	100	84.091	ENSANAG00000028229	-	80	84.848	Aotus_nancymaae
ENSG00000183684	ALYREF	97	98.054	ENSBTAG00000008498	ALYREF	100	98.054	Bos_taurus
ENSG00000183684	ALYREF	100	98.485	ENSCJAG00000039942	ALYREF	100	98.485	Callithrix_jacchus
ENSG00000183684	ALYREF	97	97.276	ENSCAFG00000005877	ALYREF	100	97.276	Canis_familiaris
ENSG00000183684	ALYREF	97	97.276	ENSCAFG00020009815	ALYREF	100	97.276	Canis_lupus_dingo
ENSG00000183684	ALYREF	97	97.287	ENSCHIG00000017396	ALYREF	97	97.287	Capra_hircus
ENSG00000183684	ALYREF	85	82.684	ENSTSYG00000002272	ALYREF	69	97.714	Carlito_syrichta
ENSG00000183684	ALYREF	51	95.522	ENSCAPG00000014727	-	100	95.522	Cavia_aperea
ENSG00000183684	ALYREF	97	96.887	ENSCPOG00000013710	ALYREF	100	96.887	Cavia_porcellus
ENSG00000183684	ALYREF	100	98.864	ENSCCAG00000020578	-	100	98.864	Cebus_capucinus
ENSG00000183684	ALYREF	97	76.265	ENSCCAG00000030237	-	100	73.152	Cebus_capucinus
ENSG00000183684	ALYREF	100	99.242	ENSCATG00000033169	ALYREF	100	99.242	Cercocebus_atys
ENSG00000183684	ALYREF	97	88.327	ENSCLAG00000015026	ALYREF	100	88.327	Chinchilla_lanigera
ENSG00000183684	ALYREF	100	99.242	ENSCSAG00000002216	ALYREF	100	99.242	Chlorocebus_sabaeus
ENSG00000183684	ALYREF	69	96.133	ENSCANG00000034056	ALYREF	89	89.266	Colobus_angolensis_palliatus
ENSG00000183684	ALYREF	97	94.163	ENSCGRG00001018191	-	100	92.218	Cricetulus_griseus_chok1gshd
ENSG00000183684	ALYREF	72	91.099	ENSCGRG00000015871	-	90	86.559	Cricetulus_griseus_crigri
ENSG00000183684	ALYREF	70	56.186	ENSCSEG00000015438	-	98	54.187	Cynoglossus_semilaevis
ENSG00000183684	ALYREF	67	95.506	ENSDNOG00000002563	ALYREF	75	95.506	Dasypus_novemcinctus
ENSG00000183684	ALYREF	85	82.667	ENSDORG00000025849	-	73	96.111	Dipodomys_ordii
ENSG00000183684	ALYREF	67	93.258	ENSETEG00000016596	ALYREF	100	92.697	Echinops_telfairi
ENSG00000183684	ALYREF	100	97.348	ENSEASG00005005824	ALYREF	98	97.348	Equus_asinus_asinus
ENSG00000183684	ALYREF	100	97.348	ENSECAG00000018754	ALYREF	98	97.348	Equus_caballus
ENSG00000183684	ALYREF	65	97.674	ENSEEUG00000010164	ALYREF	100	97.674	Erinaceus_europaeus
ENSG00000183684	ALYREF	99	97.710	ENSFCAG00000022549	ALYREF	99	97.710	Felis_catus
ENSG00000183684	ALYREF	78	87.379	ENSFDAG00000001213	ALYREF	93	85.922	Fukomys_damarensis
ENSG00000183684	ALYREF	97	83.784	ENSGALG00000007237	ALYREF	100	83.398	Gallus_gallus
ENSG00000183684	ALYREF	97	70.189	ENSGACG00000013328	ALYREF	100	72.180	Gasterosteus_aculeatus
ENSG00000183684	ALYREF	97	82.824	ENSGAGG00000008536	ALYREF	100	82.061	Gopherus_agassizii
ENSG00000183684	ALYREF	100	99.621	ENSGGOG00000013935	ALYREF	100	99.621	Gorilla_gorilla
ENSG00000183684	ALYREF	97	93.385	ENSHGLG00000008293	ALYREF	100	93.774	Heterocephalus_glaber_female
ENSG00000183684	ALYREF	78	80.617	ENSHGLG00100006949	ALYREF	77	93.370	Heterocephalus_glaber_male
ENSG00000183684	ALYREF	97	67.790	ENSHCOG00000015046	ALYREF	100	69.118	Hippocampus_comes
ENSG00000183684	ALYREF	97	93.774	ENSJJAG00000004134	-	100	93.774	Jaculus_jaculus
ENSG00000183684	ALYREF	97	70.455	ENSLACG00000005694	ALYREF	100	71.212	Latimeria_chalumnae
ENSG00000183684	ALYREF	71	94.149	ENSLAFG00000003083	ALYREF	98	92.935	Loxodonta_africana
ENSG00000183684	ALYREF	100	96.591	ENSMFAG00000001394	ALYREF	100	96.591	Macaca_fascicularis
ENSG00000183684	ALYREF	100	99.242	ENSMMUG00000012884	ALYREF	100	99.242	Macaca_mulatta
ENSG00000183684	ALYREF	100	99.242	ENSMNEG00000043666	ALYREF	100	99.242	Macaca_nemestrina
ENSG00000183684	ALYREF	70	87.895	ENSMLEG00000043353	ALYREF	82	89.385	Mandrillus_leucophaeus
ENSG00000183684	ALYREF	97	78.599	ENSMAUG00000020552	-	100	72.932	Mesocricetus_auratus
ENSG00000183684	ALYREF	99	97.338	ENSMICG00000017403	ALYREF	99	97.338	Microcebus_murinus
ENSG00000183684	ALYREF	97	83.462	ENSMOCG00000016792	-	100	81.439	Microtus_ochrogaster
ENSG00000183684	ALYREF	97	93.774	ENSMODG00000003030	ALYREF	84	93.774	Monodelphis_domestica
ENSG00000183684	ALYREF	97	69.091	ENSMALG00000019408	ALYREF	100	72.000	Monopterus_albus
ENSG00000183684	ALYREF	97	73.930	MGP_CAROLIEiJ_G0014874	Alyref2	100	70.817	Mus_caroli
ENSG00000183684	ALYREF	97	96.109	MGP_CAROLIEiJ_G0017529	Alyref	100	96.109	Mus_caroli
ENSG00000183684	ALYREF	97	96.109	ENSMUSG00000025134	Alyref	100	96.109	Mus_musculus
ENSG00000183684	ALYREF	98	61.888	ENSMUSG00000095022	Gm20765	100	53.873	Mus_musculus
ENSG00000183684	ALYREF	89	65.106	ENSMUSG00000112931	Gm4303	63	64.706	Mus_musculus
ENSG00000183684	ALYREF	89	65.106	ENSMUSG00000096744	Gm4307	63	64.706	Mus_musculus
ENSG00000183684	ALYREF	89	63.983	ENSMUSG00000094314	Gm4301	63	63.235	Mus_musculus
ENSG00000183684	ALYREF	89	65.254	ENSMUSG00000091101	Gm4302	62	64.706	Mus_musculus
ENSG00000183684	ALYREF	97	74.031	ENSMUSG00000060244	Alyref2	100	72.481	Mus_musculus
ENSG00000183684	ALYREF	89	63.983	ENSMUSG00000096640	Gm4312	63	63.235	Mus_musculus
ENSG00000183684	ALYREF	97	62.105	ENSMUSG00000097550	Gm21304	100	53.873	Mus_musculus
ENSG00000183684	ALYREF	89	65.106	ENSMUSG00000112856	Gm4305	63	64.706	Mus_musculus
ENSG00000183684	ALYREF	97	61.278	ENSMUSG00000086727	4931428L18Rik	100	57.955	Mus_musculus
ENSG00000183684	ALYREF	97	60.902	ENSMUSG00000117091	AC153137.1	100	57.197	Mus_musculus
ENSG00000183684	ALYREF	98	61.888	ENSMUSG00000094144	Gm21312	100	53.873	Mus_musculus
ENSG00000183684	ALYREF	98	61.888	ENSMUSG00000097878	Gm8764	99	60.479	Mus_musculus
ENSG00000183684	ALYREF	98	61.888	ENSMUSG00000097427	Gm6763	99	60.479	Mus_musculus
ENSG00000183684	ALYREF	98	61.034	ENSMUSG00000090854	Gm4340	100	52.778	Mus_musculus
ENSG00000183684	ALYREF	97	62.105	ENSMUSG00000091779	Gm21293	100	53.873	Mus_musculus
ENSG00000183684	ALYREF	72	97.354	MGP_PahariEiJ_G0018656	-	99	97.354	Mus_pahari
ENSG00000183684	ALYREF	97	96.109	MGP_PahariEiJ_G0018655	-	100	96.109	Mus_pahari
ENSG00000183684	ALYREF	81	67.442	MGP_PahariEiJ_G0027254	-	84	65.700	Mus_pahari
ENSG00000183684	ALYREF	81	67.442	MGP_PahariEiJ_G0027255	-	82	65.700	Mus_pahari
ENSG00000183684	ALYREF	67	57.269	MGP_SPRETEiJ_G0016590	-	55	77.419	Mus_spretus
ENSG00000183684	ALYREF	97	73.643	MGP_SPRETEiJ_G0015679	Alyref2	100	72.093	Mus_spretus
ENSG00000183684	ALYREF	97	96.109	MGP_SPRETEiJ_G0018373	Alyref	100	96.109	Mus_spretus
ENSG00000183684	ALYREF	95	62.948	ENSMLUG00000026271	-	79	61.753	Myotis_lucifugus
ENSG00000183684	ALYREF	95	62.302	ENSMLUG00000027352	-	77	61.508	Myotis_lucifugus
ENSG00000183684	ALYREF	97	52.632	ENSMLUG00000023213	-	72	52.941	Myotis_lucifugus
ENSG00000183684	ALYREF	95	62.055	ENSMLUG00000024976	-	79	59.289	Myotis_lucifugus
ENSG00000183684	ALYREF	80	82.243	ENSMLUG00000009555	-	66	92.135	Myotis_lucifugus
ENSG00000183684	ALYREF	95	59.375	ENSMLUG00000022869	-	71	61.836	Myotis_lucifugus
ENSG00000183684	ALYREF	95	69.444	ENSMLUG00000027516	-	78	66.667	Myotis_lucifugus
ENSG00000183684	ALYREF	95	61.961	ENSMLUG00000025677	-	77	60.784	Myotis_lucifugus
ENSG00000183684	ALYREF	95	60.714	ENSMLUG00000024447	-	76	60.317	Myotis_lucifugus
ENSG00000183684	ALYREF	95	63.953	ENSMLUG00000002626	-	98	65.116	Myotis_lucifugus
ENSG00000183684	ALYREF	95	57.692	ENSMLUG00000024471	-	82	52.490	Myotis_lucifugus
ENSG00000183684	ALYREF	95	60.784	ENSMLUG00000030407	-	77	59.608	Myotis_lucifugus
ENSG00000183684	ALYREF	82	58.447	ENSMLUG00000028343	-	85	64.045	Myotis_lucifugus
ENSG00000183684	ALYREF	95	55.814	ENSMLUG00000015043	-	98	52.124	Myotis_lucifugus
ENSG00000183684	ALYREF	100	99.621	ENSNLEG00000010313	ALYREF	100	99.621	Nomascus_leucogenys
ENSG00000183684	ALYREF	80	73.810	ENSMEUG00000002210	ALYREF	92	73.810	Notamacropus_eugenii
ENSG00000183684	ALYREF	51	91.045	ENSOPRG00000005551	-	52	89.552	Ochotona_princeps
ENSG00000183684	ALYREF	97	96.154	ENSODEG00000008359	ALYREF	100	96.154	Octodon_degus
ENSG00000183684	ALYREF	97	68.727	ENSORLG00000012331	ALYREF	100	70.909	Oryzias_latipes
ENSG00000183684	ALYREF	75	89.394	ENSOGAG00000012409	ALYREF	76	93.889	Otolemur_garnettii
ENSG00000183684	ALYREF	67	97.191	ENSOARG00000017932	ALYREF	67	97.191	Ovis_aries
ENSG00000183684	ALYREF	99	97.710	ENSPPRG00000010829	ALYREF	99	97.710	Panthera_pardus
ENSG00000183684	ALYREF	55	97.241	ENSPTIG00000006399	ALYREF	81	97.241	Panthera_tigris_altaica
ENSG00000183684	ALYREF	100	99.621	ENSPTRG00000009774	ALYREF	100	99.621	Pan_troglodytes
ENSG00000183684	ALYREF	100	99.242	ENSPANG00000019265	ALYREF	100	99.242	Papio_anubis
ENSG00000183684	ALYREF	50	91.729	ENSPSIG00000017541	ALYREF	98	92.481	Pelodiscus_sinensis
ENSG00000183684	ALYREF	100	99.242	ENSPPYG00000008749	ALYREF	100	99.242	Pongo_abelii
ENSG00000183684	ALYREF	99	97.338	ENSPCOG00000020874	ALYREF	99	97.338	Propithecus_coquereli
ENSG00000183684	ALYREF	97	78.988	ENSPVAG00000017866	ALYREF	100	78.988	Pteropus_vampyrus
ENSG00000183684	ALYREF	65	98.256	ENSRNOG00000036687	Alyref	91	98.256	Rattus_norvegicus
ENSG00000183684	ALYREF	69	96.133	ENSRBIG00000039651	ALYREF	74	96.133	Rhinopithecus_bieti
ENSG00000183684	ALYREF	88	91.379	ENSRROG00000045364	ALYREF	83	97.156	Rhinopithecus_roxellana
ENSG00000183684	ALYREF	73	92.746	ENSSHAG00000010459	ALYREF	95	94.565	Sarcophilus_harrisii
ENSG00000183684	ALYREF	97	52.158	ENSSDUG00000003992	-	100	53.381	Seriola_dumerili
ENSG00000183684	ALYREF	97	53.091	ENSSLDG00000005386	-	100	53.957	Seriola_lalandi_dorsalis
ENSG00000183684	ALYREF	97	82.061	ENSSPUG00000004600	ALYREF	100	80.153	Sphenodon_punctatus
ENSG00000183684	ALYREF	97	68.100	ENSSPAG00000011178	ALYREF	97	69.892	Stegastes_partitus
ENSG00000183684	ALYREF	97	97.276	ENSSSCG00000032655	ALYREF	100	97.276	Sus_scrofa
ENSG00000183684	ALYREF	50	93.182	ENSTGUG00000003513	ALYREF	100	91.111	Taeniopygia_guttata
ENSG00000183684	ALYREF	97	69.118	ENSTRUG00000008828	ALYREF	100	67.897	Takifugu_rubripes
ENSG00000183684	ALYREF	67	95.506	ENSTBEG00000005834	ALYREF	100	95.506	Tupaia_belangeri
ENSG00000183684	ALYREF	97	96.109	ENSTTRG00000012275	ALYREF	100	96.109	Tursiops_truncatus
ENSG00000183684	ALYREF	67	83.616	ENSUAMG00000016931	ALYREF	66	81.921	Ursus_americanus
ENSG00000183684	ALYREF	67	83.051	ENSUMAG00000016384	ALYREF	65	81.356	Ursus_maritimus
ENSG00000183684	ALYREF	97	75.969	ENSXETG00000005391	alyref	100	74.517	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000018	regulation of DNA recombination	22144908.	IMP	Process
GO:0000346	transcription export complex	15833825.15998806.	IDA	Component
GO:0000398	mRNA splicing, via spliceosome	11991638.	IC	Process
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0000784	nuclear chromosome, telomeric region	24270157.	IDA	Component
GO:0001649	osteoblast differentiation	16210410.	HDA	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	11546874.11979277.14667819.15047853.17190602.17234882.18562279.19165146.23299939.29128334.	IPI	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006405	RNA export from nucleus	-	TAS	Process
GO:0006406	mRNA export from nucleus	17190602.25662211.	IMP	Process
GO:0006406	mRNA export from nucleus	-	TAS	Process
GO:0016020	membrane	16210410.	HDA	Component
GO:0016032	viral process	-	IEA	Process
GO:0016607	nuclear speck	-	IEA	Component
GO:0031124	mRNA 3'-end processing	-	TAS	Process
GO:0031297	replication fork processing	22144908.	IMP	Process
GO:0032786	positive regulation of DNA-templated transcription, elongation	22144908.	IMP	Process
GO:0035145	exon-exon junction complex	16314458.	IDA	Component
GO:0046784	viral mRNA export from host cell nucleus	18974867.	IDA	Process
GO:0070062	extracellular exosome	19056867.	HDA	Component
GO:0071013	catalytic step 2 spliceosome	11991638.	IDA	Component

Note: Click here to get the extension of tumor abbreviations.

Note: to get the extension of tumor abbreviations.