EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr19	52881365	Missense_Mutation	novel	F254S	0.11
BLCA	chr19	52881325	Silent	novel	H267H	0.25
BLCA	chr19	52881112	Silent	NA	F338F	0.53
BLCA	chr19	52888152	Silent	rs755239993	E39E	0.18
BLCA	chr19	52888166	Missense_Mutation	novel	D35H	0.08
BLCA	chr19	52881129	Missense_Mutation	novel	E333K	0.24	zf-C2H2
BLCA	chr19	52881148	Silent	NA	E326E	0.35
BLCA	chr19	52881286	Missense_Mutation	novel	K280N	0.23
BLCA	chr19	52880629	Silent	NA	C499C	0.16
BLCA	chr19	52880688	Silent	novel	L480L	0.08
BLCA	chr19	52881616	Missense_Mutation	NA	F170L	0.07
BLCA	chr19	52880830	Silent	novel	R432R	0.42
BLCA	chr19	52881739	Silent	rs776479114	R129R	0.23
BRCA	chr19	52881555	Missense_Mutation	rs770557958	C191R	0.17
BRCA	chr19	52881310	Silent	NA	P272P	0.18
BRCA	chr19	52880816	Missense_Mutation	NA	G437V	0.28
BRCA	chr19	52881869	Missense_Mutation	NA	C86S	0.17
CESC	chr19	52880680	Silent	novel	S482S	0.28
CESC	chr19	52880609	Nonsense_Mutation	novel	S506*	0.37
CESC	chr19	52888223	Nonsense_Mutation	novel	E16*	0.64
CESC	chr19	52880855	Missense_Mutation	rs765248150	R424H	0.36
CESC	chr19	52881600	Missense_Mutation	NA	L176F	0.17
CESC	chr19	52879535	3'UTR	novel		0.67
CHOL	chr19	52890288	5'UTR	novel		0.48
COAD	chr19	52881559	Nonsense_Mutation	NA	Y189*	0.23
COAD	chr19	52880837	Missense_Mutation	NA	R430I	0.56
COAD	chr19	52881027	Missense_Mutation	NA	R367W	0.39
COAD	chr19	52881754	Silent	novel	D124D	0.09
COAD	chr19	52881881	Missense_Mutation	rs138794752	I82T	0.28
COAD	chr19	52881404	Missense_Mutation	NA	G241E	0.48
COAD	chr19	52881378	Missense_Mutation	NA	C250G	0.32
COAD	chr19	52880531	3'UTR	novel		0.11
COAD	chr19	52880886	Missense_Mutation	rs149561496	E414K	0.2
COAD	chr19	52890241	Splice_Region	novel	Q5Q	0.41
COAD	chr19	52877834	3'UTR	novel		0.6
COAD	chr19	52881400	Missense_Mutation	NA	E242D	0.16
COAD	chr19	52881680	Missense_Mutation	rs200745884	R149Q	0.17
COAD	chr19	52881895	Missense_Mutation	novel	Q77H	0.11
COAD	chr19	52880643	Missense_Mutation	NA	N495D	0.32
COAD	chr19	52880744	Missense_Mutation	rs758231454	R461K	0.16
COAD	chr19	52880991	Missense_Mutation	novel	H379Y	0.04
COAD	chr19	52881032	Missense_Mutation	NA	A365V	0.31
COAD	chr19	52881278	Missense_Mutation	novel	A283V	0.3
ESCA	chr19	52881773	Missense_Mutation	novel	K118T	0.38
ESCA	chr19	52881855	Missense_Mutation	novel	E91K	0.3
ESCA	chr19	52881973	Silent	novel	S51S	0.28
GBM	chr19	52881543	Missense_Mutation	rs755970222	D195N	0.36
GBM	chr19	52881212	Missense_Mutation	novel	E305G	0.07
HNSC	chr19	52881901	Silent	NA	Q75Q	0.06
HNSC	chr19	52880781	Missense_Mutation	novel	A449T	0.09
HNSC	chr19	52881278	In_Frame_Del	novel	K280_A283delinsN	0.21
HNSC	chr19	52881092	Missense_Mutation	novel	E345V	0.71	zf-C2H2
HNSC	chr19	52881415	Missense_Mutation	novel	R237S	0.12
HNSC	chr19	52880924	Missense_Mutation	rs748325945	A401V	0.35
HNSC	chr19	52880654	Missense_Mutation	NA	P491L	0.08
KIRC	chr19	52880586	3'UTR	novel		0.25
KIRC	chr19	52881768	Missense_Mutation	NA	T120A	0.14
KIRC	chr19	52881769	Missense_Mutation	NA	L119F	0.14
KIRC	chr19	52881471	Missense_Mutation	rs780919455	C219G	0.34
KIRP	chr19	52881689	Missense_Mutation	NA	L146S	0.43
LGG	chr19	52880942	Frame_Shift_Del	novel	*S395Ifs86**	0.27
LIHC	chr19	52881031	Silent	NA	A365A	0.41
LIHC	chr19	52881085	Missense_Mutation	novel	H347Q	0.27	zf-C2H2
LIHC	chr19	52881032	Missense_Mutation	NA	A365V	0.05
LUAD	chr19	52881927	Missense_Mutation	novel	E67K	0.04
LUAD	chr19	52888132	Missense_Mutation	NA	S46F	0.14
LUAD	chr19	52880708	Missense_Mutation	novel	Q473L	0.69
LUAD	chr19	52880888	Missense_Mutation	novel	Y413C	0.4
LUAD	chr19	52880904	Missense_Mutation	novel	T408A	0.2
LUAD	chr19	52881597	Missense_Mutation	NA	E177Q	0.11
LUAD	chr19	52888206	Silent	novel	E21E	0.22
LUAD	chr19	52880762	Missense_Mutation	NA	H455P	0.21
LUAD	chr19	52880679	Missense_Mutation	novel	L483I	0.18
LUSC	chr19	52880563	3'UTR	novel		0.11
LUSC	chr19	52881938	Missense_Mutation	NA	Q63P	0.4
LUSC	chr19	52880805	Missense_Mutation	novel	H441Y	0.2
LUSC	chr19	52881028	Silent	novel	F366F	0.18
LUSC	chr19	52881974	Missense_Mutation	novel	S51C	0.1
LUSC	chr19	52880953	Silent	NA	G391G	0.11
LUSC	chr19	52880988	Missense_Mutation	NA	T380P	0.4
LUSC	chr19	52880723	Missense_Mutation	NA	S468Y	0.1
LUSC	chr19	52881233	Missense_Mutation	novel	E298V	0.07
LUSC	chr19	52888176	Silent	novel	T31T	0.16
LUSC	chr19	52880827	Missense_Mutation	NA	R433S	0.24
LUSC	chr19	52881437	Frame_Shift_Ins	novel	*A230Gfs8**	0.43
LUSC	chr19	52881870	Missense_Mutation	NA	C86S	0.39
LUSC	chr19	52881936	Missense_Mutation	NA	G64S	0.28
LUSC	chr19	52880705	Missense_Mutation	NA	C474F	0.41
PAAD	chr19	52881495	Missense_Mutation	novel	H211Y	0.13
PAAD	chr19	52881899	Missense_Mutation	novel	R76K	0.21
READ	chr19	52880978	Missense_Mutation	novel	R383I	0.05
READ	chr19	52880996	Missense_Mutation	novel	R377I	0.37
READ	chr19	52881568	Missense_Mutation	NA	E186D	0.47
SKCM	chr19	52880655	Missense_Mutation	NA	P491S	0.31
SKCM	chr19	52881159	Missense_Mutation	NA	H323Y	0.35
SKCM	chr19	52881881	Missense_Mutation	rs138794752	I82T	0.41
SKCM	chr19	52880476	3'UTR	novel		0.31
SKCM	chr19	52881663	Missense_Mutation	NA	H155Y	0.24
SKCM	chr19	52888132	Missense_Mutation	NA	S46F	0.47
SKCM	chr19	52881861	Missense_Mutation	novel	E89K	0.32
SKCM	chr19	52874063	3'Flank	rs757075057		0.14
SKCM	chr19	52881381	Missense_Mutation	NA	E249Q	0.47
SKCM	chr19	52880889	Missense_Mutation	rs145022961	Y413H	0.5
SKCM	chr19	52880655	Missense_Mutation	NA	P491S	0.36
SKCM	chr19	52880655	Missense_Mutation	NA	P491S	0.41
SKCM	chr19	52881521	Missense_Mutation	novel	S202L	0.34
SKCM	chr19	52880654	Missense_Mutation	NA	P491L	0.15
STAD	chr19	52880891	Missense_Mutation	novel	L412R	0.22
STAD	chr19	52881823	Missense_Mutation	novel	W101C	0.18
STAD	chr19	52881826	Silent	NA	Q100Q	0.21
STAD	chr19	52881308	Missense_Mutation	novel	Y273C	0.1
STAD	chr19	52880777	Missense_Mutation	NA	F450S	0.1
STAD	chr19	52881253	Missense_Mutation	NA	H291Q	0.11
STAD	chr19	52881014	Missense_Mutation	rs770340803	R371H	0.29
STAD	chr19	52880968	Silent	NA	T386T	0.17
STAD	chr19	52881107	Missense_Mutation	rs752009361	R340H	0.61	zf-C2H2
STAD	chr19	52880855	Missense_Mutation	rs765248150	R424H	0.21
UCEC	chr19	52880439	3'UTR	novel		0.48
UCEC	chr19	52874030	3'Flank	novel		0.39
UCEC	chr19	52881771	Missense_Mutation	novel	L119V	0.31
UCEC	chr19	52881124	Silent	rs756372350	C334C	0.5
UCEC	chr19	52881188	Missense_Mutation	rs778986595	R313Q	0.44
UCEC	chr19	52880606	Missense_Mutation	novel	S507I	0.48
UCEC	chr19	52879477	3'UTR	novel		0.38
UCEC	chr19	52881296	Missense_Mutation	novel	E277G	0.46
UCEC	chr19	52880866	Missense_Mutation	NA	K420N	0.45
UCEC	chr19	52881374	Missense_Mutation	NA	G251D	0.16
UCEC	chr19	52881544	Silent	rs777480191	C194C	0.29
UCEC	chr19	52881681	Nonsense_Mutation	NA	R149*	0.09
UCEC	chr19	52881855	Missense_Mutation	NA	E91Q	0.39
UCEC	chr19	52888164	Silent	rs770988550	D35D	0.18
UCEC	chr19	52881152	Missense_Mutation	novel	G325V	0.48
UCEC	chr19	52880606	Missense_Mutation	novel	S507N	0.4
UCEC	chr19	52880887	Silent	rs755709205	Y413Y	0.31
UCEC	chr19	52881239	Missense_Mutation	NA	T296I	0.37
UCEC	chr19	52881777	Missense_Mutation	novel	K117Q	0.17
UCEC	chr19	52881785	Missense_Mutation	NA	T114I	0.37
UCEC	chr19	52881666	Missense_Mutation	novel	I154F	0.24
UCEC	chr19	52881080	Missense_Mutation	novel	R349M	0.27
UCEC	chr19	52881221	Missense_Mutation	novel	K302T	0.32
UCEC	chr19	52890283	5'UTR	novel		0.4
UCEC	chr19	52880485	3'UTR	novel		0.3
UCEC	chr19	52881668	Missense_Mutation	novel	R153K	0.36
UCEC	chr19	52880286	3'UTR	novel		1
UCEC	chr19	52874068	3'Flank	novel		0.25
UCEC	chr19	52881305	Missense_Mutation	NA	K274T	0.24
UCEC	chr19	52880442	3'UTR	novel		0.43
UCEC	chr19	52888176	Silent	novel	T31T	0.09
UCEC	chr19	52881224	Nonsense_Mutation	novel	*Y301Sfs4**	0.09
UCEC	chr19	52881772	Frame_Shift_Ins	NA	*L119Vfs3**	0.26
UCEC	chr19	52874030	3'Flank	novel		0.35
UCEC	chr19	52881976	In_Frame_Ins	novel	S50_S51insFLQKPI	0.13
UCEC	chr19	52881179	Missense_Mutation	novel	L316R	0.21
UCEC	chr19	52881740	Missense_Mutation	novel	R129K	0.17
UCEC	chr19	52880912	Missense_Mutation	novel	K405T	0.38
UCEC	chr19	52880499	3'UTR	novel		0.14
UCEC	chr19	52881374	Missense_Mutation	NA	G251D	0.34

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.3137	0.013691
CESC	DEL	0.078	0.027508
KIRP	DEL	0.0486	0.054726
PAAD	DEL	0.0761	0.035089
READ	DEL	0.097	0.23023
TGCT	DEL	0.2867	0.0046229
UCS	DEL	0.1429	0.12448

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0012	Kaplan-Meier Survival Analysis
SARC	0.016	Kaplan-Meier Survival Analysis
PRAD	0.0087	Kaplan-Meier Survival Analysis
LUSC	0.035	Kaplan-Meier Survival Analysis
KIRP	0.019	Kaplan-Meier Survival Analysis
BLCA	0.0033	Kaplan-Meier Survival Analysis
LAML	0.028	Kaplan-Meier Survival Analysis
KICH	0.034	Kaplan-Meier Survival Analysis
GBM	0.036	Kaplan-Meier Survival Analysis
LIHC	0.0024	Kaplan-Meier Survival Analysis
LGG	0.00011	Kaplan-Meier Survival Analysis
OV	0.0039	Kaplan-Meier Survival Analysis

Description

RBDs

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Description

Ensembl ID: ENSG00000182986 (Gene tree)
Gene ID: 162967
Gene Symbol: ZNF320
Alias: ZFPL|DKFZp686G16228
Full Name: zinc finger protein 320
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 33,904 bases
Position: chr19:52,863,790-52,897,693
Accession: 13842
RBP type: canonical RBP
Summary: ZNF320 encodes a Kruppel-like zinc finger protein. Members of this protein family are involved in activation or repression of transcription.[supplied by OMIM, Jul 2002]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000473091	zf-C2H2	PF00096.26	7.3e-59	1	11
ENSP00000473091	zf-C2H2	PF00096.26	7.3e-59	2	11
ENSP00000473091	zf-C2H2	PF00096.26	7.3e-59	3	11
ENSP00000473091	zf-C2H2	PF00096.26	7.3e-59	4	11
ENSP00000473091	zf-C2H2	PF00096.26	7.3e-59	5	11
ENSP00000473091	zf-C2H2	PF00096.26	7.3e-59	6	11
ENSP00000473091	zf-C2H2	PF00096.26	7.3e-59	7	11
ENSP00000473091	zf-C2H2	PF00096.26	7.3e-59	8	11
ENSP00000473091	zf-C2H2	PF00096.26	7.3e-59	9	11
ENSP00000473091	zf-C2H2	PF00096.26	7.3e-59	10	11
ENSP00000473091	zf-C2H2	PF00096.26	7.3e-59	11	11
ENSP00000473091	zf-met	PF12874.7	4.1e-14	1	2
ENSP00000473091	zf-met	PF12874.7	4.1e-14	2	2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000593618	ZNF320-201	598	-	ENSP00000472651	123 (aa)	-	M0R2L4
ENST00000594741	ZNF320-202	590	-	ENSP00000470403	86 (aa)	-	M0QZA2
ENST00000597909	ZNF320-210	754	-	-	- (aa)	-	-
ENST00000595202	ZNF320-203	531	-	-	- (aa)	-	-
ENST00000597091	ZNF320-206	658	-	ENSP00000468995	155 (aa)	-	M0QX96
ENST00000596215	ZNF320-205	508	-	-	- (aa)	-	-
ENST00000595635	ZNF320-204	6448	-	ENSP00000473091	509 (aa)	-	A2RRD8
ENST00000597265	ZNF320-208	583	-	ENSP00000471938	57 (aa)	-	M0R1K6
ENST00000597111	ZNF320-207	552	-	ENSP00000471548	25 (aa)	-	M0R0Z8
ENST00000598199	ZNF320-211	502	-	-	- (aa)	-	-
ENST00000601334	ZNF320-213	558	-	-	- (aa)	-	-
ENST00000597856	ZNF320-209	582	-	-	- (aa)	-	-
ENST00000600930	ZNF320-212	720	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000182986's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000182986	rs6509701	19	52880932	?	Psychosis in Alzheimer's disease	22005930	[NR]	1.4084507	EFO_0000249\|EFO_0005940

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000182986's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000182986	ZNF320	100	98.246	ENSCATG00000042172	-	100	90.177	Cercocebus_atys
ENSG00000182986	ZNF320	99	95.050	ENSCSAG00000001956	-	100	95.050	Chlorocebus_sabaeus
ENSG00000182986	ZNF320	100	96.491	ENSCANG00000031077	-	100	94.892	Colobus_angolensis_palliatus
ENSG00000182986	ZNF320	100	98.821	ENSGGOG00000014972	-	100	98.821	Gorilla_gorilla
ENSG00000182986	ZNF320	100	98.246	ENSMFAG00000005779	-	99	90.119	Macaca_fascicularis
ENSG00000182986	ZNF320	100	98.246	ENSMMUG00000012085	-	100	90.177	Macaca_mulatta
ENSG00000182986	ZNF320	93	89.429	ENSMNEG00000039739	-	100	89.429	Macaca_nemestrina
ENSG00000182986	ZNF320	91	89.154	ENSMLEG00000011375	-	99	89.154	Mandrillus_leucophaeus
ENSG00000182986	ZNF320	99	96.634	ENSNLEG00000006053	-	99	96.634	Nomascus_leucogenys
ENSG00000182986	ZNF320	100	98.821	ENSPPAG00000029412	-	100	98.821	Pan_paniscus
ENSG00000182986	ZNF320	100	99.018	ENSPTRG00000011427	ZNF320	100	99.018	Pan_troglodytes
ENSG00000182986	ZNF320	100	96.610	ENSPANG00000031583	-	100	89.628	Papio_anubis

Note: Click here to get the extension of tumor abbreviations.

Note: to get the extension of tumor abbreviations.