EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
27611951	Aberrant expression of KPNA2 is associated with a poor prognosis and contributes to OCT4 nuclear transportation in bladder cancer.	Oncotarget	2016 Nov 8	Zhou J	doi: 10.18632/oncotarget.11889.
20393006	Significance of karyopherin-{alpha} 2 (KPNA2) expression in esophageal squamous cell carcinoma.	Anticancer Res	2010 Mar	Sakai M	-
22962582	Overexpression of karyopherin 2 in human ovarian malignant germ cell tumor correlates with poor prognosis.	PLoS One	2012	He L	doi: 10.1371/journal.pone.0042992
24799195	Prosurvival function of the cellular apoptosis susceptibility/importin-α1 transport cycle is repressed by p53 in liver cancer.	Hepatology	2014 Sep	Winkler J	doi: 10.1002/hep.27207
16188882	Importin KPNA2 is required for proper nuclear localization and multiple functions of NBS1.	J Biol Chem	2005 Nov 25	Tseng SF	-
30115078	KPNA2 promotes metabolic reprogramming in glioblastomas by regulation of c-myc.	J Exp Clin Cancer Res	2018 Aug 16	Li J	doi: 10.1186/s13046-018-0861-9.
22125623	Overexpression of Kpnβ1 and Kpnα2 importin proteins in cancer derives from deregulated E2F activity.	PLoS One	2011	van der Watt PJ	doi: 10.1371/journal.pone.0027723
20859152	Overexpression of karyopherin-2 in epithelial ovarian cancer and correlation with poor prognosis.	Obstet Gynecol	2010 Oct	Zheng M	doi: 10.1097/AOG.0b013e3181f104ce.
20658535	Importin subunit alpha-2 is identified as a potential biomarker for non-small cell lung cancer by integration of the cancer cell secretome and tissue transcriptome.	Int J Cancer	2011 May 15	Wang CI	doi: 10.1002/ijc.25568.
16818692	Molecular profiling of laser-microdissected matched tumor and normal breast tissue identifies karyopherin alpha2 as a potential novel prognostic marker in breast cancer.	Clin Cancer Res	2006 Jul 1	Dahl E	-
23536776	Molecular profiling of multiple human cancers defines an inflammatory cancer-associated molecular pattern and uncovers KPNA2 as a uniform poor prognostic cancer marker.	PLoS One	2013	Rachidi SM	doi: 10.1371/journal.pone.0057911
19117056	The Karyopherin proteins, Crm1 and Karyopherin beta1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation.	Int J Cancer	2009 Apr 15	van der Watt PJ	doi: 10.1002/ijc.24146.
23749771	Nuclear karyopherin-α2 expression in primary lesions and metastatic lymph nodes was associated with poor prognosis and progression in gastric cancer.	Carcinogenesis	2013 Oct	Altan B	doi: 10.1093/carcin/bgt214
17899179	KPNA2 protein expression in invasive breast carcinoma and matched peritumoral ductal carcinoma in situ.	Virchows Arch	2007 Nov	Dankof A	-
21220479	KPNA2 expression is an independent adverse predictor of biochemical recurrence after radical prostatectomy.	Clin Cancer Res	2011 Mar 1	Mortezavi A	doi: 10.1158/1078-0432.CCR-10-0081
25728791	Quantitative proteomics reveals a novel role of karyopherin alpha 2 in cell migration through the regulation of vimentin-pErk protein complex levels in lung cancer.	J Proteome Res	2015 Apr 3	Wang CI	doi: 10.1021/pr501097a
23887301	High nuclear karyopherin α 2 expression is a strong and independent predictor of biochemical recurrence in prostate cancer patients treated by radical prostatectomy.	Mod Pathol	2014 Jan	Grupp K	doi: 10.1038/modpathol.2013.127
27154959	Aptamers that bind specifically to human KPNA2 (importin-α1) and efficiently interfere with nuclear transport.	J Biochem	2016 Nov	Yasuhara N	-
26887791	Cell surface localization of importin α1/KPNA2 affects cancer cell proliferation by regulating FGF1 signalling.	Sci Rep	2016 Feb 18	Yamada K	doi: 10.1038/srep21410.
24070213	Downregulation of KPNA2 in non-small-cell lung cancer is associated with Oct4 expression.	J Transl Med	2013 Sep 26	Li XL	doi: 10.1186/1479-5876-11-232.
21909132	Nuclear transport receptor karyopherin-α2 promotes malignant breast cancer phenotypes in vitro.	Oncogene	2012 Apr 19	Noetzel E	doi: 10.1038/onc.2011.403
27107455	Induction of immunogenic cell death by radiation-upregulated karyopherin alpha 2 in vitro.	Eur J Cell Biol	2016 Jun-Jul	Song KH	doi: 10.1016/j.ejcb.2016.04.002
18561322	Nuclear karyopherin alpha2 expression predicts poor survival in patients with advanced breast cancer irrespective of treatment intensity.	Int J Cancer	2008 Sep 15	Gluz O	doi: 10.1002/ijc.23628.
26626145	Karyopherin alpha 2 is a novel prognostic marker and a potential therapeutic target for colon cancer.	J Exp Clin Cancer Res	2015 Dec 1	Zhang Y	doi: 10.1186/s13046-015-0261-3.
21330047	High expression of karyopherin-α2 defines poor prognosis in non-muscle-invasive bladder cancer and in patients with invasive bladder cancer undergoing radical cystectomy.	Eur Urol	2011 May	Jensen JB	doi: 10.1016/j.eururo.2011.01.048
28875407	Karyopherin α-2 is a reliable marker for identification of patients with high-risk stage II colorectal cancer.	J Cancer Res Clin Oncol	2017 Dec	Jeong D	doi: 10.1007/s00432-017-2512-5
27009856	mTOR regulates proteasomal degradation and Dp1/E2F1- mediated transcription of KPNA2 in lung cancer cells.	Oncotarget	2016 May 3	Wang CI	doi: 10.18632/oncotarget.8170.
27078844	MicroRNA-26b inhibits tumor metastasis by targeting the KPNA2/c-jun pathway in human gastric cancer.	Oncotarget	2016 Jun 28	Tsai MM	doi: 10.18632/oncotarget.8629.
27974678	Prognostic value of increased KPNA2 expression in some solid tumors: A systematic review and meta-analysis.	Oncotarget	2017 Jan 3	Zhou LN	doi: 10.18632/oncotarget.13863.
30254209	E2F1 and E2F7 differentially regulate KPNA2 to promote the development of gallbladder cancer.	Oncogene	2019 Feb	Xiang S	doi: 10.1038/s41388-018-0494-7

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr17	68037485	Missense_Mutation	rs369989302	R68H	0.15
BLCA	chr17	68037463	Missense_Mutation	rs782088901	T61A	0.54
BLCA	chr17	68044014	Missense_Mutation	NA	Q369H	0.48
BLCA	chr17	68037379	Missense_Mutation	novel	E33Q	0.32
BLCA	chr17	68045773	Missense_Mutation	novel	A450V	0.42
BLCA	chr17	68040743	Silent	novel	Q93Q	0.13
BLCA	chr17	68042186	Missense_Mutation	novel	P135H	0.15
BRCA	chr17	68044031	Missense_Mutation	NA	N375S	0.24
BRCA	chr17	68046771	3'UTR	novel		0.17
BRCA	chr17	68044004	Missense_Mutation	rs782787344	R366H	0.24
BRCA	chr17	68040699	Missense_Mutation	NA	D79N	0.24
BRCA	chr17	68044051	Missense_Mutation	novel	L382F	0.08
BRCA	chr17	68037367	Missense_Mutation	rs782272780	R29C	0.46
CESC	chr17	68042260	Missense_Mutation	NA	D160H	0.24
CESC	chr17	68043900	Silent	NA	V331V	0.2
CESC	chr17	68043311	Missense_Mutation	NA	G293V	0.21
CESC	chr17	68043286	Nonsense_Mutation	NA	R285*	0.09
CESC	chr17	68042982	Missense_Mutation	NA	D217H	0.21
CESC	chr17	68044490	Nonsense_Mutation	novel	S445*	0.05
COAD	chr17	68037199	Missense_Mutation	rs183061920	D23N	0.3
COAD	chr17	68043112	Missense_Mutation	rs782396125	R227C	0.1
COAD	chr17	68042110	Missense_Mutation	novel	P110S	0.22
COAD	chr17	68043168	Silent	rs782575040	P245P	0.25
COAD	chr17	68043854	Missense_Mutation	NA	A316V	0.26
COAD	chr17	68046749	3'UTR	novel		0.27
ESCA	chr17	68044001	Missense_Mutation	novel	G365V	0.15
GBM	chr17	68042156	Missense_Mutation	novel	V125G	0.04
GBM	chr17	68043279	Silent	novel	P282P	0.06
GBM	chr17	68042119	Missense_Mutation	novel	D113Y	0.05
GBM	chr17	68043258	Silent	novel	I275I	0.1
GBM	chr17	68042174	Missense_Mutation	novel	T131N	0.08
GBM	chr17	68042184	Silent	novel	S134S	0.11
GBM	chr17	68043179	Missense_Mutation	novel	V249A	0.2
GBM	chr17	68046641	3'UTR	novel		0.45
GBM	chr17	68037471	Silent	rs782745827	P63P	0.36
HNSC	chr17	68043134	Missense_Mutation	rs782797109	S234C	0.3
HNSC	chr17	68043193	Missense_Mutation	novel	P254S	0.14
HNSC	chr17	68045919	Missense_Mutation	novel	E499K	0.19
HNSC	chr17	68044394	Missense_Mutation	novel	I413N	0.25
HNSC	chr17	68037457	Missense_Mutation	novel	D59N	0.45
HNSC	chr17	68043915	Silent	rs781940531	A336A	0.18
HNSC	chr17	68046569	Frame_Shift_Ins	novel	*A523Gfs6**	0.21
KIRC	chr17	68046580	Missense_Mutation	NA	G525V	0.26
KIRP	chr17	68043200	Missense_Mutation	novel	L256S	0.54
LGG	chr17	68043971	Missense_Mutation	novel	A355V	0.36
LIHC	chr17	68044434	Missense_Mutation	NA	M426I	0.12
LIHC	chr17	68043995	Missense_Mutation	novel	T363R	0.45
LIHC	chr17	68045786	Silent	novel	L454L	0.19
LIHC	chr17	68042219	Missense_Mutation	NA	N146S	0.69
LUAD	chr17	68037179	Missense_Mutation	novel	R16K	0.28
LUAD	chr17	68042278	Missense_Mutation	NA	A166S	0.19
LUAD	chr17	68042949	Missense_Mutation	NA	V206F	0.4
LUAD	chr17	68045903	Missense_Mutation	NA	E493D	0.19
LUSC	chr17	68044006	Nonsense_Mutation	NA	Q367*	0.22
LUSC	chr17	68046649	3'UTR	novel		0.15
LUSC	chr17	68043286	Nonsense_Mutation	NA	R285*	0.39
LUSC	chr17	68037181	Missense_Mutation	NA	F17I	0.69
OV	chr17	68042922	Nonsense_Mutation	novel	R197*	0.09
OV	chr17	68042975	Silent	novel	A214A	0.08
OV	chr17	68042114	Missense_Mutation	novel	P111L	0.11
OV	chr17	68043205	Frame_Shift_Ins	novel	*R258Pfs16**	0.15
OV	chr17	68042292	Silent	novel	L170L	0.17
OV	chr17	68043165	Silent	novel	P244P	0.03
OV	chr17	68042239	Missense_Mutation	novel	E153Q	0.04
OV	chr17	68044366	Missense_Mutation	novel	Y404N	0.06
OV	chr17	68043104	Missense_Mutation	novel	G224V	0.07
OV	chr17	68042201	Missense_Mutation	novel	S140F	0.07
READ	chr17	68044497	Silent	NA	I447I	0.11
READ	chr17	68044048	Missense_Mutation	novel	F381V	0.09
SARC	chr17	68045872	Missense_Mutation	novel	S483F	0.18
SARC	chr17	68045821	Missense_Mutation	novel	E466A	0.33
SKCM	chr17	68037451	Missense_Mutation	novel	P57S	0.48
SKCM	chr17	68044343	Missense_Mutation	NA	E396A	0.26
SKCM	chr17	68045887	Missense_Mutation	rs781870365	S488L	0.32
SKCM	chr17	68037387	Silent	NA	N35N	0.54
SKCM	chr17	68042146	Missense_Mutation	NA	P122S	0.46
SKCM	chr17	68037116	5'UTR	novel		0.39
SKCM	chr17	68040746	Silent	NA	L94L	0.28
SKCM	chr17	68044497	Silent	NA	I447I	0.05
SKCM	chr17	68043205	Missense_Mutation	NA	R258W	0.37
SKCM	chr17	68043319	Missense_Mutation	NA	P296S	0.16
STAD	chr17	68044357	Missense_Mutation	rs782484137	V401M	0.08
STAD	chr17	68037456	Silent	NA	D58D	0.09
STAD	chr17	68043286	Nonsense_Mutation	NA	R285*	0.18
STAD	chr17	68037481	Missense_Mutation	NA	N67H	0.33
STAD	chr17	68042287	Missense_Mutation	NA	S169P	0.34
STAD	chr17	68044032	Frame_Shift_Del	novel	*H376Pfs9**	0.06
STAD	chr17	68037199	Missense_Mutation	rs183061920	D23H	0.22
STAD	chr17	68040746	Silent	NA	L94L	0.18
STAD	chr17	68044484	Missense_Mutation	NA	A443V	0.12
THCA	chr17	68044318	Splice_Region	novel		0.41
UCEC	chr17	68037434	Missense_Mutation	NA	R51I	0.24
UCEC	chr17	68043112	Missense_Mutation	rs782396125	R227C	0.45
UCEC	chr17	68046609	3'UTR	novel		0.51
UCEC	chr17	68043206	Missense_Mutation	rs374149935	R258Q	0.46
UCEC	chr17	68037417	Missense_Mutation	novel	D45E	0.45
UCEC	chr17	68044497	Silent	novel	I447I	0.23
UCEC	chr17	68043146	Missense_Mutation	novel	R238H	0.38
UCEC	chr17	68045896	Missense_Mutation	novel	L491S	0.39
UCEC	chr17	68044061	Missense_Mutation	novel	V385A	0.32
UCEC	chr17	68043975	Silent	rs374422131	T356T	0.04
UCEC	chr17	68042109	Frame_Shift_Ins	novel	*I112Pfs2**	0.37
UCEC	chr17	68046521	Silent	rs782305218	N505N	0.27
UCEC	chr17	68044350	Silent	rs1136736	V398V	0.32
UCEC	chr17	68043131	Missense_Mutation	NA	L233H	0.04
UCEC	chr17	68045912	Missense_Mutation	NA	F496L	0.68
UCEC	chr17	68045791	Missense_Mutation	novel	E456G	0.04
UCEC	chr17	68045912	Missense_Mutation	NA	F496L	0.33
UCEC	chr17	68037472	Silent	novel	L64L	0.17
UCEC	chr17	68046603	3'UTR	novel		0.27
UCEC	chr17	68044393	Missense_Mutation	novel	I413L	0.38
UCEC	chr17	68037178	Nonsense_Mutation	novel	R16*	0.39
UCEC	chr17	68042293	Silent	novel	L171L	0.42
UCEC	chr17	68046632	3'UTR	rs1059424		0.28

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.3897	0.00012456
COAD	AMP	0.1818	0.00359
KIRP	AMP	0.6667	0.14801
LGG	AMP	0.0624	1.52e-05
READ	AMP	0.1879	0.15915
SARC	AMP	0.2335	0.032181
THCA	DEL	0.002	0.221
UVM	AMP	0.1625	0.054583

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0082	Kaplan-Meier Survival Analysis
KIRC	0.0044	Kaplan-Meier Survival Analysis
STAD	0.026	Kaplan-Meier Survival Analysis
SARC	0.029	Kaplan-Meier Survival Analysis
MESO	0.00011	Kaplan-Meier Survival Analysis
ACC	0.00012	Kaplan-Meier Survival Analysis
HNSC	0.0062	Kaplan-Meier Survival Analysis
SKCM	0.00077	Kaplan-Meier Survival Analysis
KIRP	0.00013	Kaplan-Meier Survival Analysis
COAD	0.00032	Kaplan-Meier Survival Analysis
PAAD	0.017	Kaplan-Meier Survival Analysis
PCPG	0.048	Kaplan-Meier Survival Analysis
BLCA	0.0071	Kaplan-Meier Survival Analysis
READ	0.026	Kaplan-Meier Survival Analysis
KICH	0.0068	Kaplan-Meier Survival Analysis
UCEC	0.026	Kaplan-Meier Survival Analysis
LIHC	0.00011	Kaplan-Meier Survival Analysis
CHOL	0.014	Kaplan-Meier Survival Analysis
LUAD	0.00011	Kaplan-Meier Survival Analysis
UVM	0.00011	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathway

Phenotype

GWAS

PPI

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000182481 (Gene tree)
Gene ID: 3838
Gene Symbol: KPNA2
Alias: SRP1alpha|IPOA1|QIP2|RCH1
Full Name: karyopherin subunit alpha 2
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Plus strand
Length: 11,336 bases
Position: chr17:68,035,519-68,046,854
Accession: 6395
Summary: The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
8777717	Localization, interaction, and RNA binding properties of the V(D)J recombination-activating proteins RAG1 and RAG2.	Immunity	1995 Dec	Spanopoulou E	-
15342649	AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1: involvement in the nuclear import of RNA-binding protein HuR.	J Biol Chem	2004 Nov 12	Wang W	-
17919121	Polyamines modulate the subcellular localization of RNA-binding protein HuR through AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1.	Biochem J	2008 Jan 15	Zou T	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000583269	KPNA2-205	611	-	ENSP00000463320	50 (aa)	-	J3QL07
ENST00000582898	KPNA2-204	394	-	-	- (aa)	-	-
ENST00000579754	KPNA2-203	569	-	ENSP00000462331	143 (aa)	-	J3KS65
ENST00000537025	KPNA2-202	2456	-	ENSP00000438483	529 (aa)	-	P52292
ENST00000583392	KPNA2-206	507	-	-	- (aa)	-	-
ENST00000584026	KPNA2-207	561	-	ENSP00000463602	134 (aa)	-	J3QLL0
ENST00000330459	KPNA2-201	2181	-	ENSP00000332455	529 (aa)	-	P52292

Gene Model

Click here to download 's gene model file

Pathway

Pathway ID	Pathway Name	Source
hsa05164	Influenza A	KEGG

Phenotype

ensgID	Trait	pValue	Pubmed ID
ENSG00000182481	Alcoholism	5.86989e-005	22978509

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000182481	rs62084690	17	68039295	A	Self-reported math ability	30038396	[0.0098-0.018] unit increase	0.0139	EFO_0004875
ENSG00000182481	rs62084693	17	68039994	?	Lung function (FEV1/FVC)	30595370			EFO_0004713

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000182481's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000182481	KPNA2	95	38.077	WBGene00002073	ima-2	97	38.077	Caenorhabditis_elegans
ENSG00000182481	KPNA2	100	94.518	ENSMUSG00000018362	Kpna2	100	95.294	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000018	regulation of DNA recombination	8016130.	TAS	Process
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0005515	protein binding	9168958.9405152.9497340.10353244.10523667.10980193.11024021.11971900.12551970.15507604.15870280.15942031.17324944.19668212.19883659.20551905.20701745.20965181.21385873.21988832.24965446.25416956.25556234.25609649.26420826.26496610.29042515.	IPI	Function
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	7754385.	TAS	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006259	DNA metabolic process	9168958.	TAS	Process
GO:0006607	NLS-bearing protein import into nucleus	17324944.	IDA	Process
GO:0008139	nuclear localization sequence binding	17324944.	IDA	Function
GO:0008565	protein transporter activity	-	IEA	Function
GO:0016020	membrane	19946888.	HDA	Component
GO:0019054	modulation by virus of host process	-	TAS	Process
GO:0042826	histone deacetylase binding	10869435.	IPI	Function
GO:0043657	host cell	-	IEA	Component
GO:0061608	nuclear import signal receptor activity	-	IEA	Function
GO:0075506	entry of viral genome into host nucleus through nuclear pore complex via importin	28189564.	IMP	Process
GO:0098892	extrinsic component of postsynaptic specialization membrane	15603742.	IDA	Component
GO:0098978	glutamatergic synapse	15603742.	EXP	Component
GO:0098978	glutamatergic synapse	15603742.	IDA	Component
GO:0099527	postsynapse to nucleus signaling pathway	15603742.	EXP	Process
GO:0099527	postsynapse to nucleus signaling pathway	15603742.	IDA	Process
GO:1903902	positive regulation of viral life cycle	28189564.	IMP	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathway

Phenotype

GWAS

PPI

Ortholog

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.