EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
27730215	The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer.	Sci Adv	2016 Oct 7	Law EK	-
29140415	APOBEC3A/B deletion polymorphism and cancer risk.	Carcinogenesis	2018 Feb 9	Gansmo LB	doi: 10.1093/carcin/bgx131.
25750306	APOBEC3B: a potential factor suppressing growth of human hepatocellular carcinoma cells.	Anticancer Res	2015 Mar	Wu PF	-
27044816	APOBEC3B expression in drug resistant MCF-7 breast cancer cell lines.	Biomed Pharmacother	2016 Apr	Onguru O	doi: 10.1016/j.biopha.2016.02.004
24154874	APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma.	Cancer Res	2013 Dec 15	Leonard B	doi: 10.1158/0008-5472.CAN-13-1753
26476745	APOBEC3B high expression status is associated with aggressive phenotype in Japanese breast cancers.	Breast Cancer	2016 Sep	Tsuboi M	doi: 10.1007/s12282-015-0641-8
26191203	The roles of APOBEC3B in gastric cancer.	Int J Clin Exp Pathol	2015 May 1	Zhang J	-
27155849	Analysis of APOBEC3A/3B germline deletion polymorphism in breast, cervical and oral cancers from South India and its impact on miRNA regulation.	Tumour Biol	2016 Sep	Revathidevi S	-
23598277	APOBEC3 cytidine deaminases in double-strand DNA break repair and cancer promotion.	Cancer Res	2013 Jun 15	Nowarski R	doi: 10.1158/0008-5472.CAN-13-0728
26320772	Impact of functional germline variants and a deletion polymorphism in APOBEC3A and APOBEC3B on breast cancer risk and survival in a Swedish study population.	J Cancer Res Clin Oncol	2016 Jan	Ghler S	doi: 10.1007/s00432-015-2038-7
26682542	Integrative genomic analysis reveals functional diversification of APOBEC gene family in breast cancer.	Hum Genomics	2015 Dec 18	Zhang Y	doi: 10.1186/s40246-015-0056-9.
23599896	DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis.	Elife	2013 Apr 16	Taylor BJ	doi: 10.7554/eLife.00534.
25401976	FHIT loss-induced DNA damage creates optimal APOBEC substrates: Insights into APOBEC-mediated mutagenesis.	Oncotarget	2015 Feb 20	Waters CE	-
24728294	Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer.	Nat Genet	2014 May	Nik-Zainal S	doi: 10.1038/ng.2955
25123150	Elevated APOBEC3B correlates with poor outcomes for estrogen-receptor-positive breast cancers.	Horm Cancer	2014 Dec	Sieuwerts AM	doi: 10.1007/s12672-014-0196-8
27977754	Expression of APOBEC3B mRNA in Primary Breast Cancer of Japanese Women.	PLoS One	2016 Dec 15	Tokunaga E	doi: 10.1371/journal.pone.0168090
27552096	The 29.5 kb APOBEC3B Deletion Polymorphism Is Not Associated with Clinical Outcome of Breast Cancer.	PLoS One	2016 Aug 23	Liu J	doi: 10.1371/journal.pone.0161731
28141868	Progressive APOBEC3B mRNA expression in distant breast cancer metastases.	PLoS One	2017 Jan 31	Sieuwerts AM	doi: 10.1371/journal.pone.0171343
28977491	p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells.	Nucleic Acids Res	2017 Nov 2	Periyasamy M	doi: 10.1093/nar/gkx721.
28062980	Assessment of an APOBEC3B truncating mutation, c.783delG, in patients with breast cancer.	Breast Cancer Res Treat	2017 Feb	Radmanesh H	doi: 10.1007/s10549-016-4100-9
28825669	Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression.	Viruses	2017 Aug 21	Warren CJ	doi: 10.3390/v9080233.
30130388	Evaluation of APOBEC3B Recognition Motifs by NMR Reveals Preferred Substrates.	ACS Chem Biol	2018 Sep 21	Liu M	doi: 10.1021/acschembio.8b00639
30457868	Structural Analysis of the Active Site and DNA Binding of Human Cytidine Deaminase APOBEC3B.	J Chem Theory Comput	2019 Jan 8	Hou S	doi: 10.1021/acs.jctc.8b00545

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr22	38982456	Translation_Start_Site	NA	M1?	0.58
BLCA	chr22	38992495	3'UTR	novel		0.43
BLCA	chr22	38992031	Splice_Region	novel		0.17
BLCA	chr22	38992544	3'UTR	novel		0.36
BLCA	chr22	38992457	3'UTR	novel		0.47
BLCA	chr22	38985963	Missense_Mutation	novel	S109C	0.12
BLCA	chr22	38985809	Splice_Region	novel		0.32
BRCA	chr22	38992513	3'UTR	novel		0.07
BRCA	chr22	38991500	Nonsense_Mutation	novel	Q298*	0.06
BRCA	chr22	38986032	Missense_Mutation	rs766117548	R132Q	0.2
BRCA	chr22	38984194	Nonsense_Mutation	NA	S46*	0.66
BRCA	chr22	38991540	Missense_Mutation	rs377377948	R311H	0.05	APOBEC_N
BRCA	chr22	38992060	Frame_Shift_Del	novel	*V349Gfs71**	0.16	APOBEC_N
CESC	chr22	38985833	Missense_Mutation	NA	H66Y	0.19
CESC	chr22	38982410	5'UTR	novel		0.34
CESC	chr22	38989577	Silent	NA	L230L	0.33
CESC	chr22	38992528	3'UTR	novel		0.12
COAD	chr22	38986075	Silent	NA	T146T	0.38
COAD	chr22	38991515	Missense_Mutation	rs772434543	V303M	0.11	APOBEC_N
COAD	chr22	38991524	Missense_Mutation	rs747498277	R306C	0.29	APOBEC_N
COAD	chr22	38991393	Missense_Mutation	novel	V262A	0.1
COAD	chr22	38992506	3'UTR	novel		0.2
COAD	chr22	38991578	Missense_Mutation	NA	Q324K	0.23	APOBEC_N
COAD	chr22	38991505	Missense_Mutation	novel	E299D	0.72
COAD	chr22	38982433	5'UTR	novel		0.07
COAD	chr22	38989460	Nonsense_Mutation	novel	L192*	0.06
COAD	chr22	38992136	Missense_Mutation	rs747995529	R374Q	0.25	APOBEC_N
GBM	chr22	38985900	Missense_Mutation	novel	I88T	0.03
GBM	chr22	38986068	Missense_Mutation	rs200407707	R144H	0.35
GBM	chr22	38985837	Missense_Mutation	novel	A67V	0.2
HNSC	chr22	38989559	Missense_Mutation	novel	D224E	0.2
HNSC	chr22	38982463	Missense_Mutation	novel	Q4E	0.53
HNSC	chr22	38984215	Missense_Mutation	novel	G53V	0.76
HNSC	chr22	38991513	Missense_Mutation	novel	H302R	0.06	APOBEC_N
HNSC	chr22	38991517	Silent	novel	V303V	0.1
KIRC	chr22	38984183	Silent	NA	K42K	0.1
KIRC	chr22	38992593	3'UTR	novel		0.2
KIRP	chr22	38991402	Missense_Mutation	novel	L265W	0.34
LGG	chr22	38986390	Missense_Mutation	rs771690446	R183C	0.16
LGG	chr22	38991532	Silent	rs144471703	F308F	0.15
LIHC	chr22	38992136	Frame_Shift_Del	novel	*A375Pfs23**	0.22	APOBEC_N
LIHC	chr22	38992600	3'UTR	novel		0.14
LIHC	chr22	38991538	Silent	novel	A310A	0.2
LUAD	chr22	38989545	Missense_Mutation	NA	V220L	0.13
LUAD	chr22	38982403	5'Flank	novel		0.3
LUAD	chr22	38992584	3'UTR	novel		0.36
LUSC	chr22	38986091	Nonsense_Mutation	novel	E152*	0.14
LUSC	chr22	38984121	Missense_Mutation	novel	E22Q	0.07
LUSC	chr22	38985993	Missense_Mutation	novel	S119F	0.11
LUSC	chr22	38992078	Missense_Mutation	novel	P355S	0.18	APOBEC_N
LUSC	chr22	38984226	Missense_Mutation	novel	G57S	0.44
OV	chr22	38986035	Frame_Shift_Del	novel	*R133Sfs5**	0.1
OV	chr22	38991492	Missense_Mutation	rs149274572	A295V	0.32
PAAD	chr22	38986038	Missense_Mutation	rs751320407	A134V	0.14
PRAD	chr22	38986331	Missense_Mutation	rs758686056	N163S	0.22
PRAD	chr22	38986068	Missense_Mutation	rs200407707	R144H	0.22
PRAD	chr22	38989563	Missense_Mutation	NA	G226S	0.33
SARC	chr22	38984207	Nonsense_Mutation	novel	W50*	0.26
SARC	chr22	38984208	Missense_Mutation	NA	D51N	0.26
SKCM	chr22	38985958	Silent	NA	F107F	0.38
SKCM	chr22	38992078	Missense_Mutation	novel	P355S	0.28	APOBEC_N
SKCM	chr22	38991455	Missense_Mutation	novel	P283S	0.4
SKCM	chr22	38991456	Missense_Mutation	novel	P283L	0.41
SKCM	chr22	38991331	Splice_Site	novel	X242_splice	0.26
SKCM	chr22	38984169	Missense_Mutation	novel	E38K	0.36
SKCM	chr22	38984201	Silent	NA	L48L	0.33
SKCM	chr22	38991395	Missense_Mutation	novel	P263S	0.3
SKCM	chr22	38992448	3'UTR	novel		0.17
SKCM	chr22	38992475	3'UTR	novel		0.8
SKCM	chr22	38991382	Silent	novel	F258F	0.29
SKCM	chr22	38985851	Missense_Mutation	NA	L72F	0.07
STAD	chr22	38992136	Missense_Mutation	rs747995529	R374Q	0.53	APOBEC_N
STAD	chr22	38992067	Missense_Mutation	rs1053813	R351H	0.2	APOBEC_N
STAD	chr22	38986067	Missense_Mutation	NA	R144S	0.27
STAD	chr22	38986378	Missense_Mutation	NA	A179T	0.27
STAD	chr22	38991484	Silent	NA	E292E	0.18
STAD	chr22	38991620	Missense_Mutation	novel	Y338H	0.17	APOBEC_N
STAD	chr22	38984098	Missense_Mutation	rs551433639	R14Q	0.57
UCEC	chr22	38989521	Missense_Mutation	rs148246014	R212C	0.3
UCEC	chr22	38991426	Missense_Mutation	novel	Y273C	0.14
UCEC	chr22	38991623	Missense_Mutation	NA	D339N	0.14	APOBEC_N
UCEC	chr22	38992457	3'UTR	novel		0.11
UCEC	chr22	38992687	3'UTR	novel		0.18
UCEC	chr22	38991525	Missense_Mutation	rs772607602	R306H	0.17	APOBEC_N
UCEC	chr22	38992654	3'UTR	novel		0.5
UCEC	chr22	38989582	Missense_Mutation	novel	D232G	0.21
UCEC	chr22	38992594	3'UTR	novel		0.29
UCEC	chr22	38986323	Silent	NA	F160F	0.25
UCEC	chr22	38984155	Missense_Mutation	novel	T33I	0.22
UCEC	chr22	38991594	Missense_Mutation	novel	A329D	0.14	APOBEC_N
UCEC	chr22	38991540	Missense_Mutation	rs377377948	R311H	0.34	APOBEC_N
UCEC	chr22	38989522	Missense_Mutation	rs113792154	R212H	0.34
UCEC	chr22	38982456	Translation_Start_Site	novel	M1?	0.46
UCEC	chr22	38992590	3'UTR	novel		0.44
UCEC	chr22	38985921	Frame_Shift_Del	novel	*C97Afs20**	0.28
UCEC	chr22	38982432	5'UTR	novel		0.32
UCEC	chr22	38985907	Nonsense_Mutation	novel	W90*	0.31
UCEC	chr22	38986365	Silent	NA	F174F	0.6
UCEC	chr22	38989466	Missense_Mutation	novel	M193I	0.35
UCEC	chr22	38986365	Silent	NA	F174F	0.38
UCEC	chr22	38992127	Missense_Mutation	novel	G371E	0.46	APOBEC_N
UCEC	chr22	38989518	Missense_Mutation	rs200770515	R211W	0.28
UCEC	chr22	38992545	3'UTR	novel		0.22
UCEC	chr22	38984191	Missense_Mutation	rs145424338	R45H	0.26
UCEC	chr22	38985827	Nonsense_Mutation	novel	Q64*	0.11
UCEC	chr22	38991454	Silent	novel	S282S	0.23
UCEC	chr22	38991617	Missense_Mutation	novel	T337A	0.5	APOBEC_N
UCEC	chr22	38992135	Missense_Mutation	rs781129393	R374W	0.32	APOBEC_N
UCEC	chr22	38992530	3'UTR	novel		0.45

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
PCPG	DEL	0.3333	0.044123
THCA	DEL	0.1563	0.046486
THYM	DEL	0.0813	0.063154

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0082	Kaplan-Meier Survival Analysis
ACC	0.00012	Kaplan-Meier Survival Analysis
LUSC	0.028	Kaplan-Meier Survival Analysis
KIRP	0.0052	Kaplan-Meier Survival Analysis
PAAD	0.0044	Kaplan-Meier Survival Analysis
CESC	0.0001	Kaplan-Meier Survival Analysis
LIHC	0.018	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
CHOL	0.04	Kaplan-Meier Survival Analysis
UVM	0.0029	Kaplan-Meier Survival Analysis
OV	0.042	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000179750 (Gene tree)
Gene ID: 9582
Gene Symbol: APOBEC3B
Alias: PHRBNL|FLJ21201
Full Name: apolipoprotein B mRNA editing enzyme catalytic subunit 3B
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 10,458 bases
Position: chr22:38,982,347-38,992,804
Accession: 17352
RBP type: canonical RBP
Summary: This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000327459	APOBEC_N	PF08210.11	1.3e-96	1	2
ENSP00000327459	APOBEC_N	PF08210.11	1.3e-96	2	2
ENSP00000385060	APOBEC_N	PF08210.11	3.9e-96	1	2
ENSP00000385060	APOBEC_N	PF08210.11	3.9e-96	2	2
ENSP00000385068	APOBEC_N	PF08210.11	4.5e-89	1	2
ENSP00000385068	APOBEC_N	PF08210.11	4.5e-89	2	2
ENSP00000385068	APOBEC_C	PF05240.14	4.2e-63	1	2
ENSP00000385068	APOBEC_C	PF05240.14	4.2e-63	2	2
ENSP00000327459	APOBEC_C	PF05240.14	5.5e-63	1	2
ENSP00000327459	APOBEC_C	PF05240.14	5.5e-63	2	2
ENSP00000385060	APOBEC_C	PF05240.14	1.3e-62	1	2
ENSP00000385060	APOBEC_C	PF05240.14	1.3e-62	2	2

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
9274872	A cytidine deaminase expressed in the post-infective L3 stage of the filarial nematode, Brugia pahangi, has a novel RNA-binding activity.	Mol Biochem Parasitol	1997 Sep	Anant S	-
7972084	Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing.	Proc Natl Acad Sci U S A	1994 Nov 22	Kim U	-
11698249	ARCD-1, an apobec-1-related cytidine deaminase, exerts a dominant negative effect on C to U RNA editing.	Am J Physiol Cell Physiol	2001 Dec	Anant S	-
11134005	Identification of GRY-RBP as an apolipoprotein B RNA-binding protein that interacts with both apobec-1 and apobec-1 complementation factor to modulate C to U editing.	J Biol Chem	2001 Mar 30	Blanc V	-
9822632	Secondary structure for the apolipoprotein B mRNA editing site. Au-binding proteins interact with a stem loop.	J Biol Chem	1998 Nov 27	Richardson N	-
7736571	Evolutionary origins of apoB mRNA editing: catalysis by a cytidine deaminase that has acquired a novel RNA-binding motif at its active site.	Cell	1995 Apr 21	Navaratnam N	-
10688645	An AU-rich sequence element (UUUN[A/U]U) downstream of the edited C in apolipoprotein B mRNA is a high-affinity binding site for Apobec-1: binding of Apobec-1 to this motif in the 3' untranslated region of c-myc increases mRNA stability.	Mol Cell Biol	2000 Mar	Anant S	-
15721369	Complementary function of the two catalytic domains of APOBEC3G.	Virology	2005 Mar 15	Navarro F	-
22923694	Transgenerational epigenetic effects of the Apobec1 cytidine deaminase deficiency on testicular germ cell tumor susceptibility and embryonic viability.	Proc Natl Acad Sci U S A	2012 Oct 9	Nelson VR	doi: 10.1073/pnas.1207169109
24664896	The multifaceted roles of RNA binding in APOBEC cytidine deaminase functions.	Wiley Interdiscip Rev RNA	2014 Jul-Aug	Prohaska KM	doi: 10.1002/wrna.1226
30679582	A panel of eGFP reporters for single base editing by APOBEC-Cas9 editosome complexes.	Sci Rep	2019 Jan 24	Martin AS	doi: 10.1038/s41598-018-36739-9.
28575276	Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation.	Nucleic Acids Res	2017 Jul 7	Xiao X	doi: 10.1093/nar/gkx362.
7782343	Mutagenesis of apobec-1, the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme, reveals distinct domains that mediate cytosine nucleoside deaminase, RNA binding, and RNA editing activity.	J Biol Chem	1995 Jun 16	MacGinnitie AJ	-
24194514	Identification of two pentatricopeptide repeat genes required for RNA editing and zinc binding by C-terminal cytidine deaminase-like domains.	J Biol Chem	2013 Dec 20	Hayes ML	doi: 10.1074/jbc.M113.485755

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000333467	APOBEC3B-201	1533	-	ENSP00000327459	382 (aa)	-	Q9UH17
ENST00000402182	APOBEC3B-203	1844	-	ENSP00000385060	490 (aa)	-	B0QYD3
ENST00000407298	APOBEC3B-204	1282	-	ENSP00000385068	357 (aa)	-	Q9UH17
ENST00000335760	APOBEC3B-202	1359	-	ENSP00000338897	251 (aa)	-	Q9UH17

Gene Model

Click here to download ENSG00000179750's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa05170	Human immunodeficiency virus 1 infection	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000179750's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000179750	APOBEC3B	95	31.892	ENSG00000124701	APOBEC2	80	32.796
ENSG00000179750	APOBEC3B	98	52.105	ENSG00000244509	APOBEC3C	100	52.105
ENSG00000179750	APOBEC3B	99	59.530	ENSG00000128394	APOBEC3F	100	82.105
ENSG00000179750	APOBEC3B	90	35.294	ENSG00000111701	APOBEC1	96	35.294
ENSG00000179750	APOBEC3B	90	32.911	ENSG00000100298	APOBEC3H	99	33.163
ENSG00000179750	APOBEC3B	100	56.589	ENSG00000239713	APOBEC3G	100	56.589

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000179750	APOBEC3B	98	55.914	ENSCJAG00000012500	-	100	55.914	Callithrix_jacchus
ENSG00000179750	APOBEC3B	99	57.513	ENSTSYG00000035593	-	99	57.513	Carlito_syrichta
ENSG00000179750	APOBEC3B	100	61.399	ENSCCAG00000027450	-	100	61.399	Cebus_capucinus
ENSG00000179750	APOBEC3B	100	83.878	ENSCATG00000013527	-	100	83.878	Cercocebus_atys
ENSG00000179750	APOBEC3B	75	80.952	ENSCSAG00000018401	-	70	80.952	Chlorocebus_sabaeus
ENSG00000179750	APOBEC3B	100	85.102	ENSCSAG00000006445	-	100	85.102	Chlorocebus_sabaeus
ENSG00000179750	APOBEC3B	99	82.474	ENSCANG00000030513	-	97	82.474	Colobus_angolensis_palliatus
ENSG00000179750	APOBEC3B	100	92.670	ENSGGOG00000006721	APOBEC3B	100	92.670	Gorilla_gorilla
ENSG00000179750	APOBEC3B	99	81.414	ENSMFAG00000008980	APOBEC3A	99	81.443	Macaca_fascicularis
ENSG00000179750	APOBEC3B	98	81.865	ENSMMUG00000042504	APOBEC3A	97	81.383	Macaca_mulatta
ENSG00000179750	APOBEC3B	99	84.392	ENSMMUG00000004015	-	98	85.417	Macaca_mulatta
ENSG00000179750	APOBEC3B	99	81.515	ENSMNEG00000043211	-	95	81.515	Macaca_nemestrina
ENSG00000179750	APOBEC3B	100	83.508	ENSMLEG00000004809	-	100	83.508	Mandrillus_leucophaeus
ENSG00000179750	APOBEC3B	98	84.375	ENSNLEG00000015215	-	99	81.563	Nomascus_leucogenys
ENSG00000179750	APOBEC3B	100	94.286	ENSPPAG00000009288	APOBEC3B	100	94.286	Pan_paniscus
ENSG00000179750	APOBEC3B	100	85.918	ENSPTRG00000014384	APOBEC3B	100	85.918	Pan_troglodytes
ENSG00000179750	APOBEC3B	99	83.523	ENSPANG00000006941	APOBEC3B	96	78.756	Papio_anubis
ENSG00000179750	APOBEC3B	100	85.602	ENSPPYG00000011831	-	100	85.602	Pongo_abelii
ENSG00000179750	APOBEC3B	76	60.811	ENSPCOG00000017606	-	95	60.811	Propithecus_coquereli
ENSG00000179750	APOBEC3B	100	84.555	ENSRBIG00000042829	-	100	84.555	Rhinopithecus_bieti
ENSG00000179750	APOBEC3B	100	84.555	ENSRROG00000028773	APOBEC3G	100	84.555	Rhinopithecus_roxellana

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0004126	cytidine deaminase activity	21873635.	IBA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	16699599.21835787.	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0008270	zinc ion binding	-	IEA	Function
GO:0009972	cytidine deamination	-	IEA	Process
GO:0010529	negative regulation of transposition	16527742.20062055.	IDA	Process
GO:0016554	cytidine to uridine editing	21873635.	IBA	Process
GO:0045087	innate immune response	-	IEA	Process
GO:0047844	deoxycytidine deaminase activity	22457529.	IMP	Function
GO:0051607	defense response to virus	22457529.22915799.	IDA	Process
GO:0080111	DNA demethylation	21873635.	IBA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.