EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
25716692	The prognostic significance of bromodomain PHD-finger transcription factor in colorectal carcinoma and association with vimentin and E-cadherin.	J Cancer Res Clin Oncol	2015 Aug	Xiao S	doi: 10.1007/s00432-015-1937-y
30419422	BPTF promotes hepatocellular carcinoma growth by modulating hTERT signaling and cancer stem cell traits.	Redox Biol	2019 Jan	Zhao X	doi: 10.1016/j.redox.2018.10.018
30542695	Bromodomain PHDfinger transcription factor promotes glioma progression and indicates poor prognosis.	Oncol Rep	2019 Jan	Pan Y	doi: 10.3892/or.2018.6832
26899553	BPTF, a chromatin remodeling-related gene, exhibits frameshift mutations in gastric and colorectal cancers.	APMIS	2016 May	Lee JH	doi: 10.1111/apm.12512
19190132	The expression of three genes in primary non-small cell lung cancer is associated with metastatic spread to the brain.	Clin Cancer Res	2009 Mar 1	Grinberg-Rashi H	doi: 10.1158/1078-0432.CCR-08-2124

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr17	67946158	Missense_Mutation	NA	H2610Y	0.2
BLCA	chr17	67874903	Missense_Mutation	rs771413164	T583A	0.13
BLCA	chr17	67948228	Silent	rs782185025	F2742F	0.23
BLCA	chr17	67945948	Missense_Mutation	novel	T2540S	0.21
BLCA	chr17	67911130	Missense_Mutation	novel	I1208M	0.31
BLCA	chr17	67911595	Silent	novel	L1363L	0.26
BLCA	chr17	67912500	Missense_Mutation	novel	S1665L	0.26
BLCA	chr17	67945446	Silent	NA	Q2372Q	0.33
BLCA	chr17	67911627	Missense_Mutation	novel	S1374F	0.37
BLCA	chr17	67912064	Missense_Mutation	NA	E1520Q	0.23
BLCA	chr17	67894046	Missense_Mutation	NA	I934M	0.4
BLCA	chr17	67912358	Missense_Mutation	NA	D1618N	0.35
BLCA	chr17	67874816	Splice_Site	novel	X554_splice	0.43
BLCA	chr17	67911394	Silent	novel	V1296V	0.52
BLCA	chr17	67912338	Missense_Mutation	rs776598623	S1611L	0.42
BLCA	chr17	67886310	Missense_Mutation	novel	E746Q	0.25
BLCA	chr17	67854703	Silent	novel	E459E	0.23
BLCA	chr17	67912925	Missense_Mutation	novel	E1807Q	0.51
BLCA	chr17	67946203	Missense_Mutation	novel	E2625K	0.2
BLCA	chr17	67854557	Missense_Mutation	novel	V411I	0.2
BLCA	chr17	67910975	Missense_Mutation	NA	Q1157K	0.11
BLCA	chr17	67909735	Missense_Mutation	novel	S1115L	0.23
BLCA	chr17	67911192	Missense_Mutation	novel	S1229C	0.39
BLCA	chr17	67929468	Missense_Mutation	NA	G2170E	0.13
BLCA	chr17	67911381	Frame_Shift_Ins	novel	*L1293Vfs3**	0.07
BLCA	chr17	67911382	In_Frame_Ins	novel	L1293_D1294insFL	0.07
BLCA	chr17	67911326	Missense_Mutation	novel	L1274F	0.11
BLCA	chr17	67946027	Missense_Mutation	novel	Q2566L	0.08
BLCA	chr17	67922885	Missense_Mutation	novel	R1994Q	0.17
BLCA	chr17	67854431	Missense_Mutation	NA	D369N	0.18
BLCA	chr17	67891929	Silent	rs759197596	I776I	0.57
BLCA	chr17	67911821	Missense_Mutation	novel	E1439Q	0.67
BLCA	chr17	67886179	Missense_Mutation	novel	S702F	0.38
BLCA	chr17	67912759	Silent	novel	V1751V	0.2
BLCA	chr17	67918726	Silent	novel	Q1898Q	0.21
BLCA	chr17	67982256	Missense_Mutation	rs782703860	H3037D	0.28
BLCA	chr17	67911410	Missense_Mutation	NA	E1302K	0.74
BRCA	chr17	67940547	Missense_Mutation	NA	S2249L	0.19
BRCA	chr17	67983691	3'UTR	novel		0.2
BRCA	chr17	67983183	3'UTR	novel		0.09
BRCA	chr17	67893627	Silent	novel	G897G	0.09
BRCA	chr17	67983487	3'UTR	novel		0.04
BRCA	chr17	67982482	3'UTR	novel		0.59
BRCA	chr17	67909677	Missense_Mutation	NA	D1096H	0.13
BRCA	chr17	67982577	3'UTR	novel		0.16
BRCA	chr17	67854136	Silent	NA	F270F	0.14
BRCA	chr17	67929337	Splice_Region	rs759696294	G2126G	0.44
BRCA	chr17	67894058	Silent	novel	Q938Q	0.07
BRCA	chr17	67912105	Missense_Mutation	NA	I1533M	0.3
BRCA	chr17	67918814	Missense_Mutation	rs761085604	P1928S	0.14
BRCA	chr17	67912326	Missense_Mutation	NA	S1607C	0.39
BRCA	chr17	67929424	Missense_Mutation	NA	R2155S	0.17
BRCA	chr17	67931954	Missense_Mutation	NA	R2191T	0.12
BRCA	chr17	67920103	Missense_Mutation	novel	R1965S	0.12
BRCA	chr17	67984345	3'UTR	novel		0.08
BRCA	chr17	67854077	Missense_Mutation	NA	E251K	0.16
BRCA	chr17	67918811	Missense_Mutation	NA	P1927T	0.37
BRCA	chr17	67911982	In_Frame_Ins	novel	K1492_L1493insKSFPFVLL	0.13
BRCA	chr17	67946260	In_Frame_Ins	novel	Q2644delinsLDLK	0.14
BRCA	chr17	67826311	Missense_Mutation	novel	S196N	0.19
BRCA	chr17	67920100	Missense_Mutation	NA	I1964M	0.18
CESC	chr17	67948261	Silent	novel	L2753L	0.4
CESC	chr17	67911797	Missense_Mutation	NA	D1431Y	0.18
CESC	chr17	67981461	Intron	novel		0.35
CESC	chr17	67982362	3'UTR	novel		0.48
CESC	chr17	67911054	Nonsense_Mutation	NA	S1183*	0.4
CESC	chr17	67983551	3'UTR	novel		0.19
CESC	chr17	67982632	3'UTR	novel		0.16
CESC	chr17	67945477	Missense_Mutation	NA	P2383S	0.21
CESC	chr17	67911104	Nonsense_Mutation	novel	E1200*	0.11
CESC	chr17	67911105	Missense_Mutation	novel	E1200A	0.11
CESC	chr17	67911580	Missense_Mutation	novel	K1358N	0.14
CESC	chr17	67891891	Missense_Mutation	novel	P764A	0.29
CESC	chr17	67826266	Missense_Mutation	rs749305717	D181G	0.19
CESC	chr17	67984345	3'UTR	novel		0.12
CESC	chr17	67918785	Missense_Mutation	NA	R1918K	0.38
CESC	chr17	67904798	Missense_Mutation	novel	P1050S	0.39
CESC	chr17	67959574	Missense_Mutation	rs782539445	E2780K	0.41
CESC	chr17	67893692	Missense_Mutation	NA	S919L	0.16
CESC	chr17	67904823	Missense_Mutation	novel	R1058K	0.1
CESC	chr17	67875588	Missense_Mutation	rs139353057	V633M	0.59
CESC	chr17	67912574	Missense_Mutation	NA	E1690K	0.24
CESC	chr17	67854209	Missense_Mutation	NA	L295V	0.38
CHOL	chr17	67984039	3'UTR	novel		0.29
COAD	chr17	67911363	Missense_Mutation	novel	L1286R	0.14
COAD	chr17	67959766	Frame_Shift_Ins	novel	*D2844Afs20**	0.08
COAD	chr17	67911458	Missense_Mutation	novel	K1318Q	0.09
COAD	chr17	67948163	Missense_Mutation	novel	R2721C	0.17
COAD	chr17	67948150	Frame_Shift_Del	NA	*K2718Nfs36**	0.12
COAD	chr17	67911043	Missense_Mutation	NA	K1179N	0.27
COAD	chr17	67904772	Missense_Mutation	NA	H1041L	0.53
COAD	chr17	67959754	Missense_Mutation	NA	E2840K	0.14
COAD	chr17	67945996	Missense_Mutation	novel	P2556S	0.35
COAD	chr17	67931916	Silent	rs773414397	I2178I	0.25
COAD	chr17	67982338	3'UTR	novel		0.08
COAD	chr17	67946199	Silent	NA	V2623V	0.32
COAD	chr17	67912381	Silent	novel	D1625D	0.37
COAD	chr17	67945622	Missense_Mutation	novel	V2431A	0.4
COAD	chr17	67982552	3'UTR	novel		0.43
COAD	chr17	67975815	Silent	NA	E2987E	0.11
COAD	chr17	67911613	Silent	NA	D1369D	0.32
COAD	chr17	67948150	Frame_Shift_Del	NA	*K2718Nfs36**	0.3
COAD	chr17	67826310	Missense_Mutation	novel	S196G	0.1
COAD	chr17	67894077	Nonsense_Mutation	NA	E945*	0.24
COAD	chr17	67894167	Splice_Site	novel	X974_splice	0.1
COAD	chr17	67909738	Missense_Mutation	NA	K1116T	0.22
COAD	chr17	67947775	Missense_Mutation	novel	S2682N	0.11
COAD	chr17	67912072	Missense_Mutation	NA	E1522D	0.43
COAD	chr17	67892012	Missense_Mutation	NA	K804T	0.42
COAD	chr17	67894077	Nonsense_Mutation	NA	E945*	0.42
COAD	chr17	67904724	Missense_Mutation	NA	E1025A	0.24
COAD	chr17	67853997	Missense_Mutation	novel	I224N	0.06
COAD	chr17	67909636	Missense_Mutation	rs764527892	R1082Q	0.39
COAD	chr17	67920084	Missense_Mutation	rs556375365	R1959Q	0.23
COAD	chr17	67946322	Missense_Mutation	novel	K2664N	0.06
COAD	chr17	67946324	Missense_Mutation	novel	Q2665L	0.06
COAD	chr17	67946276	Missense_Mutation	rs782594079	R2649H	0.14
COAD	chr17	67948150	Frame_Shift_Del	NA	*K2718Nfs36**	0.12
COAD	chr17	67854702	Missense_Mutation	NA	E459G	0.37
COAD	chr17	67886304	Missense_Mutation	novel	Q744E	0.35
DLBC	chr17	67959787	Nonsense_Mutation	novel	K2851*	0.51
ESCA	chr17	67909590	In_Frame_Del	rs749412697	N1071_E1074del	0.38
ESCA	chr17	67909663	Missense_Mutation	novel	P1091L	0.14
ESCA	chr17	67945870	Nonsense_Mutation	novel	Q2514*	0.38
ESCA	chr17	67984296	3'UTR	rs117652432		0.14
GBM	chr17	67964230	Silent	novel	D2886D	0.76
GBM	chr17	67854583	Silent	novel	P419P	0.17
GBM	chr17	67874969	Missense_Mutation	novel	D605Y	0.41
GBM	chr17	67911463	Silent	novel	V1319V	0.26
GBM	chr17	67911732	Missense_Mutation	novel	S1409Y	0.17
GBM	chr17	67959830	Missense_Mutation	novel	D2865G	0.45
GBM	chr17	67928540	Silent	NA	Q2105Q	0.25
GBM	chr17	67929349	Silent	novel	V2130V	0.2
GBM	chr17	67894077	Nonsense_Mutation	NA	E945*	0.12
GBM	chr17	67944193	Missense_Mutation	novel	Q2300R	0.04
GBM	chr17	67946155	Missense_Mutation	rs782403455	T2609P	0.1
GBM	chr17	67912428	Missense_Mutation	novel	T1641M	0.46
GBM	chr17	67982407	3'UTR	rs543416875		0.21
GBM	chr17	67909685	Silent	novel	V1098V	0.08
GBM	chr17	67893456	Silent	NA	F840F	0.42
GBM	chr17	67948158	Missense_Mutation	NA	R2719Q	0.95
GBM	chr17	67891982	Missense_Mutation	NA	Q794L	0.5
HNSC	chr17	67913007	Missense_Mutation	novel	Y1834C	0.18
HNSC	chr17	67940439	Missense_Mutation	novel	G2213V	0.31
HNSC	chr17	67893494	Missense_Mutation	novel	N853S	0.1
HNSC	chr17	67982382	3'UTR	novel		0.38
HNSC	chr17	67911779	Nonsense_Mutation	novel	Q1425*	0.13
HNSC	chr17	67909677	Missense_Mutation	novel	D1096N	0.23
HNSC	chr17	67891942	Missense_Mutation	novel	R781W	0.32
HNSC	chr17	67918818	Missense_Mutation	novel	G1929V	0.33
KICH	chr17	67893414	Silent	novel	T826T	0.04
KICH	chr17	67964255	Missense_Mutation	NA	R2895C	0.2
KICH	chr17	67913175	Missense_Mutation	NA	G1890D	0.06
KIRC	chr17	67913012	Nonsense_Mutation	NA	K1836*	0.37
KIRC	chr17	67854706	In_Frame_Ins	novel	P460_I461insT	0.04
KIRC	chr17	67854708	Frame_Shift_Ins	novel	*I461Mfs17**	0.04
KIRC	chr17	67975903	Frame_Shift_Ins	novel	*A3017Efs15**	0.04
KIRC	chr17	67975905	Silent	novel	A3017A	0.02
KIRC	chr17	67959588	Missense_Mutation	NA	M2784I	0.41
KIRC	chr17	67959589	Missense_Mutation	NA	Q2785E	0.4
KIRC	chr17	67964366	Missense_Mutation	NA	D2932H	0.41
KIRC	chr17	67854137	Missense_Mutation	novel	C271R	0.28
KIRP	chr17	67912172	Missense_Mutation	novel	R1556G	0.28
KIRP	chr17	67928380	Missense_Mutation	novel	T2052R	0.34
KIRP	chr17	67964394	Missense_Mutation	NA	R2941L	0.1
KIRP	chr17	67922965	Frame_Shift_Ins	novel	*E2022Gfs7**	0.63
KIRP	chr17	67948196	Nonsense_Mutation	novel	Q2732*	0.22
KIRP	chr17	67920067	Silent	novel	V1953V	0.33
LAML	chr17	67946257	Nonsense_Mutation	novel	Q2643*	0.06
LGG	chr17	67903792	Silent	novel	L975L	0.06
LGG	chr17	67945551	Silent	novel	P2407P	0.44
LGG	chr17	67854569	Missense_Mutation	novel	E415K	0.35
LGG	chr17	67911893	Missense_Mutation	novel	V1463F	0.64
LGG	chr17	67959823	Missense_Mutation	novel	K2863E	0.22
LGG	chr17	67982255	Silent	novel	S3036S	0.53
LGG	chr17	67903797	Missense_Mutation	NA	R977Q	0.09
LIHC	chr17	67866505	Missense_Mutation	novel	Y493C	0.46
LIHC	chr17	67924545	Splice_Site	novel	X2029_splice	0.29
LIHC	chr17	67854753	Frame_Shift_Ins	novel	*R476Sfs21**	0.08
LIHC	chr17	67826236	Missense_Mutation	NA	D171G	0.16
LIHC	chr17	67875575	Missense_Mutation	novel	D628E	0.47
LIHC	chr17	67874856	Missense_Mutation	rs781047955	I567T	0.48
LIHC	chr17	67911635	Missense_Mutation	NA	S1377G	0.39
LIHC	chr17	67893519	Silent	NA	A861A	0.4
LIHC	chr17	67909686	Missense_Mutation	novel	K1099E	0.26
LIHC	chr17	67945997	Missense_Mutation	NA	P2556L	0.18
LIHC	chr17	67909729	Missense_Mutation	NA	D1113G	0.16
LIHC	chr17	67928357	Splice_Region	novel	K2044K	0.11
LIHC	chr17	67924552	Missense_Mutation	NA	E2031G	0.36
LUAD	chr17	67966599	Missense_Mutation	NA	E2954Q	0.08
LUAD	chr17	67826232	Missense_Mutation	novel	D170N	0.12
LUAD	chr17	67944253	Missense_Mutation	novel	Q2320L	0.36
LUAD	chr17	67910957	Missense_Mutation	novel	E1151Q	0.17
LUAD	chr17	67911580	Missense_Mutation	novel	K1358N	0.15
LUAD	chr17	67959857	Missense_Mutation	rs781919328	T2874M	0.07
LUAD	chr17	67931916	Silent	rs773414397	I2178I	0.14
LUAD	chr17	67911713	Missense_Mutation	novel	G1403R	0.61
LUAD	chr17	67928563	Missense_Mutation	NA	T2113I	0.14
LUAD	chr17	67875628	Missense_Mutation	novel	S646L	0.21
LUAD	chr17	67940636	Missense_Mutation	novel	T2279A	0.46
LUAD	chr17	67909656	Frame_Shift_Ins	novel	*I1089Rfs7**	0.07
LUAD	chr17	67948171	Frame_Shift_Ins	novel	*S2724Wfs10**	0.06
LUAD	chr17	67893692	Missense_Mutation	NA	S919L	0.06
LUAD	chr17	67875734	Missense_Mutation	novel	Q681H	0.22
LUAD	chr17	67911052	Missense_Mutation	novel	K1182N	0.16
LUAD	chr17	67913035	Silent	novel	K1843K	0.07
LUAD	chr17	67910906	Missense_Mutation	novel	D1134N	0.14
LUAD	chr17	67886146	Missense_Mutation	novel	C691Y	0.1
LUAD	chr17	67875639	Missense_Mutation	novel	S650G	0.23
LUAD	chr17	67891875	Silent	rs576607155	G758G	0.37
LUAD	chr17	67893444	Missense_Mutation	novel	I836M	0.05
LUAD	chr17	67854345	Missense_Mutation	novel	Y340S	0.17
LUAD	chr17	67948287	Missense_Mutation	NA	D2762V	0.29
LUAD	chr17	67854602	Missense_Mutation	NA	E426K	0.08
LUAD	chr17	67854028	Missense_Mutation	NA	E234D	0.34
LUAD	chr17	67928388	Missense_Mutation	NA	A2055T	0.12
LUAD	chr17	67913185	Missense_Mutation	NA	W1893C	0.16
LUAD	chr17	67854739	Missense_Mutation	novel	W471C	0.1
LUAD	chr17	67910957	Missense_Mutation	novel	E1151Q	0.22
LUAD	chr17	67912609	Silent	novel	V1701V	0.09
LUAD	chr17	67875666	Missense_Mutation	novel	G659W	0.32
LUAD	chr17	67894058	Missense_Mutation	novel	Q938H	0.13
LUAD	chr17	67975821	Silent	novel	L2989L	0.09
LUAD	chr17	67854745	Silent	NA	L473L	0.13
LUAD	chr17	67929465	Missense_Mutation	novel	G2169V	0.16
LUAD	chr17	67853970	Missense_Mutation	rs754887842	R215H	0.14
LUAD	chr17	67966585	Missense_Mutation	novel	A2949V	0.15
LUAD	chr17	67924553	Missense_Mutation	novel	E2031D	0.36
LUSC	chr17	67912043	Missense_Mutation	NA	K1513E	0.35
LUSC	chr17	67946149	Missense_Mutation	novel	V2607L	0.21
LUSC	chr17	67911712	Missense_Mutation	NA	E1402D	0.64
LUSC	chr17	67909640	Silent	novel	S1083S	0.16
LUSC	chr17	67959547	Missense_Mutation	NA	L2771M	0.27
LUSC	chr17	67854416	Silent	NA	L364L	0.16
LUSC	chr17	67853987	Missense_Mutation	novel	E221Q	0.13
LUSC	chr17	67854733	Missense_Mutation	NA	K469N	0.27
LUSC	chr17	67891924	Missense_Mutation	novel	R775G	0.24
LUSC	chr17	67966617	Missense_Mutation	novel	D2960N	0.15
LUSC	chr17	67893596	Missense_Mutation	NA	G887E	0.27
LUSC	chr17	67918718	Missense_Mutation	NA	R1896G	0.27
LUSC	chr17	67918811	Missense_Mutation	novel	P1927A	0.51
LUSC	chr17	67928464	Missense_Mutation	NA	I2080R	0.15
LUSC	chr17	67928401	Missense_Mutation	novel	T2059S	0.28
LUSC	chr17	67903842	Missense_Mutation	NA	K992R	0.13
LUSC	chr17	67922876	Missense_Mutation	NA	S1991I	0.36
LUSC	chr17	67909649	Missense_Mutation	novel	K1086N	0.42
LUSC	chr17	67912553	Missense_Mutation	novel	L1683V	0.05
LUSC	chr17	67893609	Missense_Mutation	NA	W891C	0.23
LUSC	chr17	67929337	Splice_Region	rs759696294	G2126G	0.47
LUSC	chr17	67940462	Missense_Mutation	novel	Q2221E	0.17
OV	chr17	67904786	Missense_Mutation	NA	V1046L	0.39
OV	chr17	67911634	Missense_Mutation	NA	K1376N	0.46
OV	chr17	67922988	Splice_Region	novel	E2028E	0.03
OV	chr17	67911366	Nonsense_Mutation	novel	Y1287*	0.05
OV	chr17	67924571	Silent	novel	A2037A	0.24
OV	chr17	67924572	Missense_Mutation	novel	V2038L	0.24
OV	chr17	67946026	Missense_Mutation	NA	Q2566K	0.3
OV	chr17	67945564	Missense_Mutation	NA	Q2412E	0.67
OV	chr17	67893541	In_Frame_Ins	novel	E869delinsDGQRVFSK	0.04
OV	chr17	67911897	Missense_Mutation	novel	S1464F	0.11
OV	chr17	67911899	Missense_Mutation	novel	G1465C	0.1
OV	chr17	67911014	Missense_Mutation	novel	G1170C	0.83
PAAD	chr17	67929338	Missense_Mutation	rs201775041	V2127I	0.05
PAAD	chr17	67886168	Silent	novel	A698A	0.03
PAAD	chr17	67854434	Nonsense_Mutation	novel	Q370*	0.11
PAAD	chr17	67945733	Missense_Mutation	novel	R2468H	0.22
PAAD	chr17	67866471	Missense_Mutation	novel	D482Y	0.17
PAAD	chr17	67866477	Missense_Mutation	novel	E484K	0.16
PAAD	chr17	67909639	Missense_Mutation	novel	S1083N	0.19
PAAD	chr17	67911786	Missense_Mutation	novel	S1427N	0.12
PAAD	chr17	67928358	Nonsense_Mutation	novel	R2045*	0.15
PAAD	chr17	67975804	Nonsense_Mutation	novel	R2984*	0.15
PAAD	chr17	67959640	Missense_Mutation	novel	A2802P	0.04
PCPG	chr17	67948298	Missense_Mutation	rs782100405	E2766K	0.16
PRAD	chr17	67944321	Missense_Mutation	NA	T2343A	0.42
PRAD	chr17	67945886	Missense_Mutation	NA	S2519L	0.06
PRAD	chr17	67911448	Silent	NA	D1314D	0.54
PRAD	chr17	67946097	Silent	novel	V2589V	0.47
READ	chr17	67875670	Missense_Mutation	NA	C660Y	0.31
READ	chr17	67912372	Silent	rs148696633	N1622N	0.13
READ	chr17	67909642	Frame_Shift_Ins	NA	*I1087Nfs6**	0.25
READ	chr17	67875658	Missense_Mutation	novel	S656N	0.48
READ	chr17	67894077	Nonsense_Mutation	NA	E945*	0.33
READ	chr17	67910961	Nonsense_Mutation	novel	S1152*	0.41
READ	chr17	67946114	Missense_Mutation	novel	L2595R	0.38
READ	chr17	67912216	Missense_Mutation	novel	N1570K	0.22
READ	chr17	67866553	Missense_Mutation	NA	K509T	0.2
READ	chr17	67893482	Missense_Mutation	NA	R849H	0.44
READ	chr17	67911530	Missense_Mutation	NA	D1342N	0.35
READ	chr17	67922883	Silent	NA	L1993L	0.29
SARC	chr17	67946108	Missense_Mutation	novel	I2593S	0.09
SARC	chr17	67922904	Silent	novel	T2000T	0.04
SARC	chr17	67866555	Missense_Mutation	novel	D510N	0.38
SARC	chr17	67966591	Missense_Mutation	novel	P2951L	0.35
SARC	chr17	67945713	Silent	rs782112255	V2461V	0.68
SKCM	chr17	67854122	Missense_Mutation	rs765443034	R266C	0.26
SKCM	chr17	67913068	Silent	NA	L1854L	0.14
SKCM	chr17	67866647	Silent	novel	K540K	0.11
SKCM	chr17	67959643	Missense_Mutation	NA	P2803S	0.42
SKCM	chr17	67945630	Missense_Mutation	novel	H2434Y	0.35
SKCM	chr17	67913002	Silent	NA	P1832P	0.17
SKCM	chr17	67945835	Missense_Mutation	NA	P2502L	0.1
SKCM	chr17	67911377	Nonsense_Mutation	rs145463211	R1291*	0.18
SKCM	chr17	67920083	Nonsense_Mutation	NA	R1959*	0.28
SKCM	chr17	67911122	Missense_Mutation	rs753831908	E1206K	0.59
SKCM	chr17	67913159	Missense_Mutation	novel	P1885S	0.24
SKCM	chr17	67913160	Missense_Mutation	novel	P1885L	0.25
SKCM	chr17	67909586	Silent	NA	K1065K	0.21
SKCM	chr17	67931990	Missense_Mutation	NA	I2203S	0.27
SKCM	chr17	67911648	Missense_Mutation	NA	S1381L	0.67
SKCM	chr17	67912225	Silent	rs757112658	I1573I	0.29
SKCM	chr17	67946273	Missense_Mutation	novel	K2648R	0.39
SKCM	chr17	67893622	Missense_Mutation	NA	H896Y	0.35
SKCM	chr17	67826296	Missense_Mutation	NA	E191V	0.07
SKCM	chr17	67874960	Missense_Mutation	NA	L602F	0.63
SKCM	chr17	67975901	Missense_Mutation	NA	C3016F	0.51
SKCM	chr17	67909679	Missense_Mutation	novel	D1096E	0.4
SKCM	chr17	67912796	Missense_Mutation	NA	P1764S	0.28
SKCM	chr17	67944309	Missense_Mutation	NA	P2339S	0.26
SKCM	chr17	67912620	Missense_Mutation	novel	S1705F	0.39
SKCM	chr17	67918738	Silent	NA	S1902S	0.38
SKCM	chr17	67940487	Missense_Mutation	NA	S2229F	0.32
SKCM	chr17	67903823	Missense_Mutation	NA	K986E	0.21
SKCM	chr17	67913095	Silent	novel	I1863I	0.12
SKCM	chr17	67913096	Nonsense_Mutation	NA	R1864*	0.11
SKCM	chr17	67975919	Missense_Mutation	novel	S3022L	0.41
SKCM	chr17	67854179	Missense_Mutation	NA	E285K	0.21
SKCM	chr17	67911550	Missense_Mutation	NA	S1348R	0.42
SKCM	chr17	67912125	Missense_Mutation	NA	P1540L	0.14
SKCM	chr17	67975886	Missense_Mutation	NA	S3011F	0.56
SKCM	chr17	67948200	Missense_Mutation	NA	N2733S	0.08
SKCM	chr17	67894115	Silent	NA	V957V	0.24
SKCM	chr17	67875642	Missense_Mutation	novel	P651S	0.23
SKCM	chr17	67910950	Missense_Mutation	NA	M1148I	0.16
SKCM	chr17	67911526	Silent	NA	F1340F	0.31
SKCM	chr17	67918724	Nonsense_Mutation	NA	Q1898*	0.23
SKCM	chr17	67854303	Nonsense_Mutation	NA	W326*	0.14
SKCM	chr17	67894143	Nonsense_Mutation	NA	R967*	0.16
SKCM	chr17	67912875	Missense_Mutation	NA	S1790F	0.24
SKCM	chr17	67918835	Missense_Mutation	NA	T1935S	0.72
SKCM	chr17	67886297	Silent	novel	V741V	0.2
SKCM	chr17	67913109	Missense_Mutation	NA	Y1868F	0.1
SKCM	chr17	67913111	Missense_Mutation	NA	F1869L	0.1
SKCM	chr17	67894123	Missense_Mutation	NA	V960A	0.17
SKCM	chr17	67912827	Missense_Mutation	NA	S1774F	0.33
STAD	chr17	67911845	Missense_Mutation	novel	T1447S	0.29
STAD	chr17	67945504	Missense_Mutation	novel	A2392T	0.08
STAD	chr17	67854675	Frame_Shift_Del	novel	*N452Ifs22**	0.32
STAD	chr17	67903879	Silent	NA	Q1004Q	0.35
STAD	chr17	67903835	Frame_Shift_Del	rs768059042	*E993Rfs16**	0.45
STAD	chr17	67911441	Frame_Shift_Del	novel	*N1313Mfs3**	0.12
STAD	chr17	67892027	Missense_Mutation	rs751572182	G809D	0.39
STAD	chr17	67854189	Missense_Mutation	NA	V288A	0.22
STAD	chr17	67946079	Missense_Mutation	NA	Q2583H	0.24
STAD	chr17	67931954	Missense_Mutation	NA	R2191T	0.26
STAD	chr17	67948198	Missense_Mutation	novel	Q2732H	0.37
STAD	chr17	67909589	Silent	NA	N1066N	0.29
STAD	chr17	67903835	Frame_Shift_Del	rs768059042	*E993Rfs16**	0.45
STAD	chr17	67948150	Frame_Shift_Del	NA	*K2718Nfs36**	0.4
STAD	chr17	67866511	Missense_Mutation	NA	S495T	0.49
STAD	chr17	67912470	Missense_Mutation	novel	N1655S	0.21
STAD	chr17	67903882	Silent	rs546466065	A1005A	0.31
STAD	chr17	67912458	Missense_Mutation	NA	S1651I	0.39
STAD	chr17	67964394	Missense_Mutation	rs368469411	R2941H	0.3
STAD	chr17	67945449	Missense_Mutation	rs781794996	M2373I	0.32
STAD	chr17	67945959	Silent	novel	S2543S	0.17
STAD	chr17	67913096	Nonsense_Mutation	NA	R1864*	0.29
STAD	chr17	67911725	Missense_Mutation	novel	C1407R	0.14
STAD	chr17	67944365	Silent	NA	T2357T	0.22
STAD	chr17	67913100	Missense_Mutation	NA	E1865G	0.06
STAD	chr17	67893612	Silent	rs146795207	N892N	0.27
STAD	chr17	67904830	Silent	rs187203989	S1060S	0.24
STAD	chr17	67928481	Missense_Mutation	NA	T2086S	0.11
STAD	chr17	67946279	Missense_Mutation	NA	E2650G	0.06
STAD	chr17	67875644	Silent	novel	P651P	0.25
STAD	chr17	67964390	Missense_Mutation	novel	L2940I	0.13
STAD	chr17	67922844	Silent	rs763992744	T1980T	0.38
STAD	chr17	67892011	Missense_Mutation	NA	K804E	0.38
STAD	chr17	67948278	Missense_Mutation	NA	L2759P	0.18
STAD	chr17	67893483	Silent	rs763441304	R849R	0.18
STAD	chr17	67922903	Missense_Mutation	rs148728817	T2000M	0.29
STAD	chr17	67854123	Missense_Mutation	rs773171191	R266H	0.23
STAD	chr17	67912362	Missense_Mutation	NA	A1619V	0.26
STAD	chr17	67920060	Missense_Mutation	NA	R1951I	0.07
TGCT	chr17	67894077	Nonsense_Mutation	NA	E945*	0.28
THCA	chr17	67874912	Missense_Mutation	NA	D586H	0.08
THCA	chr17	67945600	Nonsense_Mutation	NA	E2424*	0.14
THCA	chr17	67891934	Missense_Mutation	novel	T778N	0.11
THCA	chr17	67948173	Frame_Shift_Ins	novel	*S2724Rfs15**	0.04
THCA	chr17	67911701	Missense_Mutation	rs200808758	M1399V	0.29
UCEC	chr17	67875635	Missense_Mutation	rs769949554	E648D	0.3
UCEC	chr17	67891993	Missense_Mutation	rs149719620	A798T	0.27
UCEC	chr17	67909636	Missense_Mutation	rs764527892	R1082Q	0.28
UCEC	chr17	67911529	Silent	rs573741875	I1341I	0.29
UCEC	chr17	67911992	Missense_Mutation	NA	R1496G	0.35
UCEC	chr17	67959548	Missense_Mutation	NA	L2771P	0.21
UCEC	chr17	67918719	Missense_Mutation	novel	R1896I	0.1
UCEC	chr17	67945430	Missense_Mutation	NA	S2367N	0.27
UCEC	chr17	67893482	Missense_Mutation	NA	R849P	0.28
UCEC	chr17	67826329	Missense_Mutation	novel	S202I	0.29
UCEC	chr17	67909624	Missense_Mutation	novel	R1078K	0.42
UCEC	chr17	67911792	Missense_Mutation	novel	E1429G	0.26
UCEC	chr17	67983795	3'UTR	novel		0.33
UCEC	chr17	67854535	Silent	NA	L403L	0.11
UCEC	chr17	67912938	Missense_Mutation	rs567290654	R1811Q	0.39
UCEC	chr17	67912328	Missense_Mutation	rs759643114	E1608K	0.35
UCEC	chr17	67928491	Missense_Mutation	novel	K2089R	0.36
UCEC	chr17	67948173	Missense_Mutation	novel	S2724N	0.13
UCEC	chr17	67893683	Missense_Mutation	novel	N916S	0.46
UCEC	chr17	67911726	Missense_Mutation	NA	C1407Y	0.35
UCEC	chr17	67892012	Missense_Mutation	NA	K804T	0.42
UCEC	chr17	67982622	3'UTR	rs559708134		0.4
UCEC	chr17	67984024	3'UTR	novel		0.35
UCEC	chr17	67910942	Missense_Mutation	rs201720584	D1146N	0.11
UCEC	chr17	67940508	Missense_Mutation	novel	N2236T	0.38
UCEC	chr17	67984159	3'UTR	novel		0.22
UCEC	chr17	67892017	Nonsense_Mutation	novel	F806*	0.07
UCEC	chr17	67920057	Missense_Mutation	NA	R1950M	0.27
UCEC	chr17	67982552	3'UTR	novel		0.48
UCEC	chr17	67854064	Silent	NA	V246V	0.31
UCEC	chr17	67911768	Missense_Mutation	NA	T1421I	0.24
UCEC	chr17	67982494	3'UTR	novel		0.34
UCEC	chr17	67911803	Missense_Mutation	novel	I1433L	0.2
UCEC	chr17	67984346	3'UTR	novel		0.37
UCEC	chr17	67893625	Missense_Mutation	NA	G897R	0.49
UCEC	chr17	67945410	Splice_Region	NA	G2360G	0.21
UCEC	chr17	67945724	Missense_Mutation	NA	S2465F	0.44
UCEC	chr17	67946287	Missense_Mutation	NA	L2653I	0.8
UCEC	chr17	67948157	Missense_Mutation	NA	R2719W	0.55
UCEC	chr17	67964255	Missense_Mutation	NA	R2895C	0.51
UCEC	chr17	67866557	Missense_Mutation	novel	D510E	0.29
UCEC	chr17	67911896	Frame_Shift_Ins	novel	*S1464Ffs6**	0.05
UCEC	chr17	67874819	Missense_Mutation	novel	E555K	1
UCEC	chr17	67918726	Missense_Mutation	NA	Q1898H	0.28
UCEC	chr17	67911489	Missense_Mutation	novel	E1328A	0.32
UCEC	chr17	67983460	3'UTR	novel		0.1
UCEC	chr17	67912056	Missense_Mutation	novel	E1517G	0.31
UCEC	chr17	67854204	Missense_Mutation	novel	A293V	0.12
UCEC	chr17	67911686	Missense_Mutation	novel	P1394S	0.14
UCEC	chr17	67911116	Nonsense_Mutation	novel	R1204*	0.17
UCEC	chr17	67912977	Missense_Mutation	novel	K1824R	0.31
UCEC	chr17	67920023	Missense_Mutation	rs780605303	E1939K	0.43
UCEC	chr17	67944276	Missense_Mutation	novel	P2328S	0.44
UCEC	chr17	67983471	3'UTR	novel		0.34
UCEC	chr17	67983988	3'UTR	novel		0.63
UCEC	chr17	67854387	Missense_Mutation	NA	Y354F	0.35
UCEC	chr17	67886183	Silent	NA	I703I	0.36
UCEC	chr17	67964385	Missense_Mutation	novel	R2938M	0.98
UCEC	chr17	67982552	3'UTR	novel		0.63
UCEC	chr17	67874880	Frame_Shift_Del	NA	*T576Qfs141**	0.45
UCEC	chr17	67983086	3'UTR	novel		0.33
UCEC	chr17	67893469	Nonsense_Mutation	novel	E845*	0.16
UCEC	chr17	67912516	Silent	novel	V1670V	0.5
UCEC	chr17	67911163	Missense_Mutation	novel	K1219N	0.52
UCEC	chr17	67964253	Missense_Mutation	novel	G2894V	0.11
UCEC	chr17	67983444	3'UTR	novel		0.36
UCEC	chr17	67975835	Missense_Mutation	NA	A2994V	0.32
UCEC	chr17	67854213	Missense_Mutation	novel	R296H	0.56
UCEC	chr17	67866471	Missense_Mutation	novel	D482Y	0.51
UCEC	chr17	67911529	Silent	rs573741875	I1341I	0.43
UCEC	chr17	67944219	Missense_Mutation	novel	P2309S	0.47
UCEC	chr17	67911463	Silent	novel	V1319V	0.3
UCEC	chr17	67983880	3'UTR	novel		0.47
UCEC	chr17	67909643	Frame_Shift_Del	rs757520968	I1087*	0.54
UCEC	chr17	67854375	Missense_Mutation	novel	E350A	0.42
UCEC	chr17	67920023	Missense_Mutation	rs780605303	E1939K	0.32
UCEC	chr17	67929383	Missense_Mutation	NA	T2142A	0.34
UCEC	chr17	67940598	Missense_Mutation	novel	P2266L	0.4
UCEC	chr17	67911524	Missense_Mutation	novel	F1340V	0.46
UCEC	chr17	67983086	3'UTR	novel		0.5
UCEC	chr17	67983282	3'UTR	novel		0.48
UCEC	chr17	67944253	Missense_Mutation	novel	Q2320R	0.28
UCEC	chr17	67945929	Silent	novel	G2533G	0.17
UCEC	chr17	67911431	Frame_Shift_Ins	novel	*N1309Rfs13**	0.11
UCEC	chr17	67981446	Intron	novel		0.4
UCEC	chr17	67984306	3'UTR	novel		0.13
UCEC	chr17	67903835	Frame_Shift_Del	rs768059042	*E993Rfs16**	0.49
UCEC	chr17	67911877	Silent	rs371084809	P1457P	0.2
UCEC	chr17	67854049	Silent	novel	E241E	0.25
UCEC	chr17	67929338	Missense_Mutation	rs201775041	V2127I	0.42
UCEC	chr17	67946211	Silent	novel	L2627L	0.26
UCEC	chr17	67854400	Missense_Mutation	novel	E358D	0.38
UCEC	chr17	67959556	Missense_Mutation	novel	D2774N	0.18
UCEC	chr17	67920022	Silent	rs758887059	S1938S	0.41
UCEC	chr17	67984159	3'UTR	novel		0.45
UCEC	chr17	67854313	Silent	novel	V329V	0.44
UCEC	chr17	67886179	Missense_Mutation	novel	S702F	0.42
UCEC	chr17	67911314	Missense_Mutation	NA	D1270Y	0.17
UCEC	chr17	67959567	Missense_Mutation	NA	I2777M	0.34
UCEC	chr17	67975911	Silent	NA	V3019V	0.22
UCEC	chr17	67945713	Silent	rs782112255	V2461V	0.41
UCEC	chr17	67982821	3'UTR	novel		0.39
UCEC	chr17	67983472	3'UTR	novel		0.29
UCEC	chr17	67946112	Silent	novel	K2594K	0.37
UCEC	chr17	67940656	Splice_Region	rs782750355	H2285H	0.28
UCEC	chr17	67886134	Missense_Mutation	novel	P687H	0.29
UCEC	chr17	67893416	Missense_Mutation	NA	K827T	0.45
UCEC	chr17	67909664	Silent	NA	P1091P	0.34
UCEC	chr17	67946130	Missense_Mutation	NA	Q2600H	0.38
UCEC	chr17	67959766	Missense_Mutation	NA	D2844Y	0.46
UCEC	chr17	67893483	Silent	novel	R849R	0.26
UCEC	chr17	67964316	Missense_Mutation	novel	C2915Y	0.06
UCEC	chr17	67893544	Missense_Mutation	novel	D870Y	0.1
UCEC	chr17	67903893	Missense_Mutation	NA	K1009T	0.25
UCEC	chr17	67912887	Missense_Mutation	NA	T1794M	0.23
UCEC	chr17	67854038	Missense_Mutation	rs779611691	V238M	0.16
UCEC	chr17	67866643	Missense_Mutation	rs150449990	N539S	0.15
UCEC	chr17	67874933	Missense_Mutation	novel	N593H	0.19
UCEC	chr17	67911378	Missense_Mutation	rs768837896	R1291Q	0.21
UCEC	chr17	67912383	Missense_Mutation	rs781602924	S1626N	0.28
UCEC	chr17	67918790	Missense_Mutation	novel	D1920N	0.35
UCEC	chr17	67932015	Missense_Mutation	novel	Q2211H	0.27
UCEC	chr17	67944362	Silent	novel	T2356T	0.46
UCEC	chr17	67948269	Missense_Mutation	novel	R2756K	0.17
UCEC	chr17	67948258	Silent	novel	I2752I	0.44
UCEC	chr17	67984027	3'UTR	novel		0.4
UCEC	chr17	67946260	Frame_Shift_Ins	novel	*Q2644Lfs7**	0.07
UCEC	chr17	67854353	Missense_Mutation	rs200853934	V343I	0.54
UCEC	chr17	67912272	Missense_Mutation	NA	R1589M	0.25
UCEC	chr17	67894049	Missense_Mutation	NA	K935N	0.4
UCEC	chr17	67893548	In_Frame_Del	NA	D872del	0.28
UCEC	chr17	67874885	Frame_Shift_Ins	novel	*D579Rfs4**	0.35
UCEC	chr17	67912062	Missense_Mutation	novel	R1519Q	0.35
UCEC	chr17	67982587	3'UTR	novel		0.36
UCEC	chr17	67983577	3'UTR	novel		0.49
UCEC	chr17	67875667	Missense_Mutation	novel	G659E	0.38
UCEC	chr17	67904803	Silent	novel	G1051G	0.26
UCEC	chr17	67983312	3'UTR	novel		0.48
UCEC	chr17	67983768	3'UTR	novel		0.32
UCEC	chr17	67984092	3'UTR	novel		0.43
UCEC	chr17	67893483	Silent	rs763441304	R849R	0.53
UCS	chr17	67920022	Silent	rs758887059	S1938S	0.72

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.3922	0.00012456
COAD	AMP	0.1885	0.00359
KIRP	AMP	0.6667	0.14801
LGG	AMP	0.0604	1.52e-05
READ	AMP	0.1879	0.15915
SARC	AMP	0.2335	0.032181
THCA	DEL	0.002	0.221
UVM	AMP	0.1625	0.054583

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
SARC	0.02	Kaplan-Meier Survival Analysis
COAD	0.049	Kaplan-Meier Survival Analysis
PAAD	0.04	Kaplan-Meier Survival Analysis
PCPG	0.029	Kaplan-Meier Survival Analysis
READ	0.0031	Kaplan-Meier Survival Analysis
LAML	0.0025	Kaplan-Meier Survival Analysis
LIHC	0.016	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000171634 (Gene tree)
Gene ID: 2186
Gene Symbol: BPTF
Alias: FAC1|NURF301|FALZ
Full Name: bromodomain PHD finger transcription factor
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 158,855 bases
Position: chr17:67,825,524-67,984,378
Accession: 3581
RBP type: non-canonical RBP
Summary: This gene was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer's disease. Analysis of the original protein (fetal Alz-50 reactive clone 1, or FAC1), identified as an 810 aa protein containing a DNA-binding domain and a zinc finger motif, suggested it might play a role in the regulation of transcription. High levels of FAC1 were detected in fetal brain and in patients with neurodegenerative diseases. The protein encoded by this gene is actually much larger than originally thought, and it also contains a C-terminal bromodomain characteristic of proteins that regulate transcription during proliferation. The encoded protein is highly similar to the largest subunit of the Drosophila NURF (nucleosome remodeling factor) complex. In Drosophila, the NURF complex, which catalyzes nucleosome sliding on DNA and interacts with sequence-specific transcription factors, is necessary for the chromatin remodeling required for transcription. Two alternative transcripts encoding different isoforms have been described completely. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000577770	BPTF-209	475	-	-	- (aa)	-	-
ENST00000582467	BPTF-216	1015	-	ENSP00000463776	339 (aa)	-	J3QQK4
ENST00000644067	BPTF-219	11036	XM_005257150	ENSP00000496182	2965 (aa)	XP_005257207	A0A2R8Y7Q1
ENST00000544778	BPTF-208	7573	-	ENSP00000440854	2457 (aa)	-	F5GXF5
ENST00000306378	BPTF-201	9688	XM_005257158	ENSP00000307208	2920 (aa)	XP_005257215	Q12830
ENST00000335221	BPTF-203	2627	-	ENSP00000334351	810 (aa)	-	A0A0A0MR81
ENST00000582406	BPTF-215	378	-	-	- (aa)	-	-
ENST00000584931	BPTF-218	571	-	-	- (aa)	-	-
ENST00000577837	BPTF-210	594	-	ENSP00000462703	64 (aa)	-	J3KSY0
ENST00000321892	BPTF-202	11292	XM_005257154	ENSP00000315454	3046 (aa)	XP_005257211	Q12830
ENST00000580465	BPTF-213	1951	-	ENSP00000462535	484 (aa)	-	J3KSK9
ENST00000583990	BPTF-217	464	-	ENSP00000463736	69 (aa)	-	J3QLW4
ENST00000467104	BPTF-206	550	-	-	- (aa)	-	-
ENST00000424123	BPTF-205	8295	-	ENSP00000388405	2764 (aa)	-	E7ETD6
ENST00000342579	BPTF-204	10607	XM_005257159	ENSP00000343837	2822 (aa)	XP_005257216	E9PE19
ENST00000544491	BPTF-207	409	-	ENSP00000443949	137 (aa)	-	F5H176
ENST00000579173	BPTF-212	770	-	-	- (aa)	-	-
ENST00000581258	BPTF-214	1582	-	ENSP00000463845	420 (aa)	-	J3QQQ8
ENST00000578307	BPTF-211	2121	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000171634's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000171634	Alcoholism	8.97663e-005	22978509
ENSG00000171634	Alcoholism	6.83565e-005	22978509
ENSG00000171634	Alcoholism	8.68089e-005	22978509
ENSG00000171634	Alcoholism	6.71392e-005	22978509
ENSG00000171634	Alcoholism	1.37004e-005	22978509
ENSG00000171634	Alcoholism	3.41477e-005	22978509
ENSG00000171634	Alcoholism	1.61778e-005	22978509
ENSG00000171634	Alcoholism	1.03515e-005	22978509
ENSG00000171634	Alcoholism	9.91355e-005	22978509
ENSG00000171634	Alcoholism	6.38813e-005	22978509
ENSG00000171634	Alcoholism	9.3695e-005	22978509
ENSG00000171634	Alcoholism	6.12785e-005	22978509
ENSG00000171634	Alcoholism	7.67214e-006	22978509
ENSG00000171634	Alcoholism	3.09899e-005	22978509
ENSG00000171634	Alcoholism	8.18644e-005	22978509
ENSG00000171634	Alcoholism	9.36801e-005	22978509
ENSG00000171634	Alcoholism	6.65594e-005	22978509
ENSG00000171634	Alcoholism	3.5341e-005	22978509
ENSG00000171634	Ankle Brachial Index	1.8233524E-005	-
ENSG00000171634	Platelet Function Tests	5.8800000E-006	-
ENSG00000171634	Platelet Function Tests	1.2741000E-005	-
ENSG00000171634	Lung Neoplasms	1.0850000E-005	-
ENSG00000171634	Lung Neoplasms	2.6220000E-005	-
ENSG00000171634	Lung Neoplasms	1.5400000E-005	-
ENSG00000171634	Lung Neoplasms	2.0860000E-005	-
ENSG00000171634	Adenocarcinoma of lung	1.2200000E-005	-
ENSG00000171634	Adenocarcinoma of lung	6.5860000E-006	-
ENSG00000171634	Adenocarcinoma of lung	5.3120000E-006	-
ENSG00000171634	Adenocarcinoma of lung	5.9030000E-006	-
ENSG00000171634	Adenocarcinoma of lung	1.9360000E-005	-
ENSG00000171634	Adenocarcinoma of lung	2E-12	27501781
ENSG00000171634	Adenocarcinoma of lung	7E-11	22797724
ENSG00000171634	Lung Neoplasms	7E-6	23143601
ENSG00000171634	Alcoholism	5E-7	27151647

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000171634	rs11870068	17	67948399	?	Alcohol dependence symptom count	27151647	[0.14-0.32] unit decrease	0.227	EFO_0007835
ENSG00000171634	rs7216064	17	67902693	A	EGFR mutation-positive lung adenocarcinoma	27501781	[1.19-1.35]	1.27	EFO_0000571
ENSG00000171634	rs7216064	17	67902693	A	Lung cancer	23143601	[1.09-1.25]	1.16	EFO_0001071
ENSG00000171634	rs7216064	17	67902693	A	Lung adenocarcinoma	22797724	[1.13-1.26]	1.2	EFO_0000571
ENSG00000171634	rs12602912	17	67873957	T	Body mass index	28892062	[0.013-0.025] kg/m2 increase	0.019	EFO_0004340
ENSG00000171634	rs4790981	17	67925718	G	Body mass index	28892062	[0.016-0.032] kg/m2 increase	0.024	EFO_0004340
ENSG00000171634	rs148803332	17	67962135	C	Neutrophil percentage of granulocytes	27863252	[0.026-0.044] unit increase	0.03498489	EFO_0007994
ENSG00000171634	rs5821446	17	67966423	AT	Eosinophil percentage of granulocytes	27863252	[0.029-0.046] unit decrease	0.03720467	EFO_0007996
ENSG00000171634	rs60432162	17	67884422	C	Sum eosinophil basophil counts	27863252	[0.03-0.048] unit increase	0.0388262	EFO_0005090\|EFO_0004842
ENSG00000171634	rs148803332	17	67962135	C	Eosinophil percentage of white cells	27863252	[0.03-0.047] unit decrease	0.03850312	EFO_0007991
ENSG00000171634	rs60432162	17	67884422	C	Eosinophil counts	27863252	[0.032-0.05] unit increase	0.04065155	EFO_0004842
ENSG00000171634	rs80135947	17	67839885	C	Hand grip strength	29691431	[0.0022-0.0038] unit decrease	0.003	EFO_0006941
ENSG00000171634	rs8073510	17	67843094	A	Hand grip strength	29691431	[0.0022-0.0038] unit increase	0.003	EFO_0006941
ENSG00000171634	rs60856912	17	67896227	T	Endometrial cancer	30093612	[1.06-1.15]	1.11	EFO_1001512
ENSG00000171634	rs60856912	17	67896227	T	Endometrial cancer (endometrioid histology)	30093612	[1.06-1.17]	1.12	EFO_1001512
ENSG00000171634	rs12602912	17	67873957	C	Body mass index	30108127	[NR] unit decrease	0.017	EFO_0004340
ENSG00000171634	rs2080090	17	67832255	?	Body fat percentage	30593698	[0.1-0.21] unit increase	0.15811	EFO_0007800
ENSG00000171634	rs2080090	17	67832255	?	Body fat percentage	30593698	[0.11-0.25] unit increase	0.18015	EFO_0007800
ENSG00000171634	rs7218014	17	67835900	?	Body mass index	30595370			EFO_0004340
ENSG00000171634	rs12449442	17	67951524	?	Macular thickness	30535121	[0.41-0.75] unit decrease	0.577	EFO_0008375
ENSG00000171634	rs11867618	17	67879471	A	Risk-taking tendency (4-domain principal component model)	30643258	[0.014-0.029] unit increase	0.021921	EFO_0008579
ENSG00000171634	rs4791212	17	67979269	?	Eosinophil counts	30595370			EFO_0004842
ENSG00000171634	rs60856912	17	67896227	T	Smoking initiation (ever regular vs never regular) (MTAG)	30643251	[0.0058-0.0116] unit increase	0.00872394	EFO_0006527

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000171634's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000171634	BPTF	94	89.663	ENSMUSG00000040481	Bptf	96	92.058	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	10727212.	IDA	Process
GO:0000790	nuclear chromatin	27141965.	IDA	Component
GO:0001892	embryonic placenta development	-	IEA	Process
GO:0005515	protein binding	14609955.15640247.21596426.	IPI	Function
GO:0005634	nucleus	10403843.14609955.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0006338	chromatin remodeling	14609955.	IDA	Process
GO:0006357	regulation of transcription by RNA polymerase II	10575013.	IMP	Process
GO:0007420	brain development	14609955.	IMP	Process
GO:0007492	endoderm development	-	IEA	Process
GO:0008094	DNA-dependent ATPase activity	14609955.	IDA	Function
GO:0008134	transcription factor binding	10727212.	IDA	Function
GO:0009952	anterior/posterior pattern specification	-	IEA	Process
GO:0016589	NURF complex	20850016.	IDA	Component
GO:0035064	methylated histone binding	-	IEA	Function
GO:0043565	sequence-specific DNA binding	10403843.	IDA	Function
GO:0043565	sequence-specific DNA binding	10575013.	IMP	Function
GO:0045944	positive regulation of transcription by RNA polymerase II	14609955.	IMP	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0048188	Set1C/COMPASS complex	27141965.	IDA	Component
GO:0070062	extracellular exosome	18570454.	HDA	Component

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.