EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
23782473	Clinicopathological features and CCT2 and PDIA2 expression in gallbladder squamous/adenosquamous carcinoma and gallbladder adenocarcinoma.	World J Surg Oncol	2013 Jun 19	Zou Q	doi: 10.1186/1477-7819-11-143.
27363653	MiR-330-5p regulates tyrosinase and PDIA3 expression and suppresses cell proliferation and invasion in cutaneous malignant melanoma.	J Surg Res	2016 Jun 15	Su BB	doi: 10.1016/j.jss.2016.03.021
20596667	ER-60 (PDIA3) is highly expressed in a newly established serous ovarian cancer cell line, YDOV-139.	Int J Oncol	2010 Aug	Chay D	-
30431082	ERp57small interfering RNA silencing can enhance the sensitivity of drugresistant human ovarian cancer cells to paclitaxel.	Int J Oncol	2019 Jan	Li S	doi: 10.3892/ijo.2018.4628
26772958	Protein disulfide isomerase A3-specific Th1 effector cells infiltrate colon cancer tissue of patients with circulating anti-protein disulfide isomerase A3 autoantibodies.	Transl Res	2016 May	Caorsi C	doi: 10.1016/j.trsl.2015.12.013
24490732	AGR2, ERp57/GRP58, and some other human protein disulfide isomerases.	Biochemistry (Mosc)	2013 Dec	Shishkin SS	doi: 10.1134/S000629791313004X.
26771192	LEDGF/p75 Overexpression Attenuates Oxidative Stress-Induced Necrosis and Upregulates the Oxidoreductase ERP57/PDIA3/GRP58 in Prostate Cancer.	PLoS One	2016 Jan 15	Basu A	doi: 10.1371/journal.pone.0146549
20035634	Differential expression of apoptotic genes PDIA3 and MAP3K5 distinguishes between low- and high-risk prostate cancer.	Mol Cancer	2009 Dec 27	Pressinotti NC	doi: 10.1186/1476-4598-8-130.
23957851	Downregulation of ERp57 expression is associated with poor prognosis in early-stage cervical cancer.	Biomarkers	2013 Nov	Chung H	doi: 10.3109/1354750X.2013.827742
27492604	Depletion of Dicer promotes epithelial ovarian cancer progression by elevating PDIA3 expression.	Tumour Biol	2016 Oct	Zhu Y	-
23625662	A transcriptome-proteome integrated network identifies endoplasmic reticulum thiol oxidoreductase (ERp57) as a hub that mediates bone metastasis.	Mol Cell Proteomics	2013 Aug	Santana-Codina N	doi: 10.1074/mcp.M112.022772
25605256	ERp57 modulates STAT3 activity in radioresistant laryngeal cancer cells and serves as a prognostic marker for laryngeal cancer.	Oncotarget	2015 Feb 20	Choe MH	-
25081282	Glucose-regulated protein 58 modulates β-catenin protein stability in a cervical adenocarcinoma cell line.	BMC Cancer	2014 Aug 1	Liao CJ	doi: 10.1186/1471-2407-14-555.
17188166	Expression and prognostic significance of prothymosin-alpha and ERp57 in human gastric cancer.	Surgery	2007 Jan	Leys CM	-
26004124	MicroRNA-148a inhibits the proliferation and promotes the paclitaxel-induced apoptosis of ovarian cancer cells by targeting PDIA3.	Mol Med Rep	2015 Sep	Zhao S	doi: 10.3892/mmr.2015.3826
26125904	PDIA3 and PDIA6 gene expression as an aggressiveness marker in primary ductal breast cancer.	Genet Mol Res	2015 Jun 26	Ramos FS	doi: 10.4238/2015.June.26.4.
17456022	The ERp57/GRp58/1,25D3-MARRS receptor: multiple functional roles in diverse cell systems.	Curr Med Chem	2007	Khanal RC	-
22266712	Downregulation of ER60 protease inhibits cellular proliferation by inducing G1/S arrest in breast cancer cells in vitro.	Anat Rec (Hoboken)	2012 Mar	Lwin ZM	doi: 10.1002/ar.22413
19714814	Comparative proteomic analysis of paclitaxel sensitive A2780 epithelial ovarian cancer cell line and its resistant counterpart A2780TC1 by 2D-DIGE: the role of ERp57.	J Proteome Res	2009 Apr	Cicchillitti L	-

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr15	43744349	5'Flank	novel		0.86
BLCA	chr15	43765482	Missense_Mutation	NA	T212S	0.42
BLCA	chr15	43765509	Missense_Mutation	novel	A221V	0.4
BLCA	chr15	43763110	Frame_Shift_Del	novel	*E170Sfs3**	0.25
BLCA	chr15	43756740	Missense_Mutation	rs553813975	G113V	0.13
BLCA	chr15	43744141	5'Flank	novel		0.65
BLCA	chr15	43769603	Missense_Mutation	NA	H408R	0.15
BRCA	chr15	43768576	Silent	novel	E372E	0.06
BRCA	chr15	43773075	3'UTR	novel		0.18
BRCA	chr15	43763097	Missense_Mutation	novel	S165G	0.12
BRCA	chr15	43744179	5'Flank	NA		0.22
BRCA	chr15	43771315	3'UTR	novel		0.23
CESC	chr15	43746585	Missense_Mutation	NA	L16V	1
CESC	chr15	43765997	Missense_Mutation	rs756782649	N277S	0.13
CESC	chr15	43761434	Silent	novel	V125V	0.4
CESC	chr15	43772887	3'UTR	novel		0.25
CESC	chr15	43771315	3'UTR	novel		0.53
CESC	chr15	43744148	5'Flank	novel		0.44
CESC	chr15	43746753	Intron	novel		0.38
COAD	chr15	43773052	3'UTR	novel		0.35
COAD	chr15	43765560	Missense_Mutation	novel	E238G	0.18
COAD	chr15	43771166	Missense_Mutation	novel	V489A	0.14
COAD	chr15	43763187	Missense_Mutation	NA	E195K	0.34
COAD	chr15	43744405	5'Flank	novel		0.28
COAD	chr15	43746699	Frame_Shift_Ins	NA	*W56Lfs11**	0.47
COAD	chr15	43771204	Frame_Shift_Del	NA	*Q502Rfs46**	0.48
COAD	chr15	43756751	Nonsense_Mutation	NA	G117*	0.1
COAD	chr15	43746699	Missense_Mutation	novel	A54T	0.07
COAD	chr15	43744516	5'Flank	rs540188450		0.18
COAD	chr15	43766906	Missense_Mutation	NA	F342L	0.76
COAD	chr15	43746711	Splice_Region	NA		0.16
COAD	chr15	43765923	Missense_Mutation	novel	K252N	0.1
COAD	chr15	43768490	Missense_Mutation	rs757380536	R344C	0.11
COAD	chr15	43765520	Frame_Shift_Ins	NA	*M227Nfs7**	0.34
ESCA	chr15	43746656	Silent	novel	I39I	0.26
GBM	chr15	43763164	Missense_Mutation	NA	T187M	0.46
GBM	chr15	43756651	Splice_Region	novel	V83V	0.32
GBM	chr15	43765554	Missense_Mutation	novel	I236S	0.12
GBM	chr15	43772997	3'UTR	novel		0.4
GBM	chr15	43746726	Intron	novel		0.34
GBM	chr15	43744445	5'Flank	novel		0.78
GBM	chr15	43766759	Missense_Mutation	novel	A293S	0.09
GBM	chr15	43753882	Missense_Mutation	novel	G76R	0.15
HNSC	chr15	43744157	5'Flank	novel		0.12
HNSC	chr15	43745061	5'Flank	novel		0.19
HNSC	chr15	43766773	Silent	novel	L297L	0.29
KIRC	chr15	43768543	Silent	NA	L361L	0.36
KIRP	chr15	43744286	5'Flank	novel		0.57
LAML	chr15	43756669	Silent	novel	T89T	0.08
LAML	chr15	43761427	Missense_Mutation	novel	G123E	0.08
LAML	chr15	43766908	Splice_Region	novel	F342F	0.12
LGG	chr15	43746478	5'UTR	novel		0.53
LGG	chr15	43771229	3'UTR	novel		0.13
LGG	chr15	43771230	3'UTR	novel		0.13
LIHC	chr15	43768548	Missense_Mutation	novel	R363I	0.39
LIHC	chr15	43751674	Intron	novel		0.22
LUAD	chr15	43765958	Missense_Mutation	NA	Y264F	0.64
LUAD	chr15	43746602	Silent	NA	L21L	0.28
LUAD	chr15	43765517	Missense_Mutation	rs772223861	E224Q	0.13
LUAD	chr15	43765969	Missense_Mutation	NA	D268Y	0.1
LUAD	chr15	43761456	Nonsense_Mutation	novel	G133*	0.55
LUAD	chr15	43745154	5'Flank	novel		0.11
LUAD	chr15	43771171	Missense_Mutation	novel	Q491E	0.53
LUAD	chr15	43766805	Missense_Mutation	novel	S308I	0.1
LUSC	chr15	43765463	Missense_Mutation	novel	F206L	0.29
LUSC	chr15	43769556	Missense_Mutation	novel	N392K	0.1
LUSC	chr15	43770249	Splice_Site	NA	X423_splice	0.12
LUSC	chr15	43770250	Missense_Mutation	NA	L423I	0.13
LUSC	chr15	43761503	Silent	novel	F148F	0.07
LUSC	chr15	43765475	Missense_Mutation	rs755677588	H210Y	0.12
OV	chr15	43744314	5'Flank	novel		0.16
OV	chr15	43766819	Missense_Mutation	novel	D313N	0.07
OV	chr15	43756657	Nonsense_Mutation	novel	C85*	0.07
OV	chr15	43745169	5'Flank	NA		0.76
OV	chr15	43765929	Missense_Mutation	NA	L254F	0.87
OV	chr15	43768508	Nonsense_Mutation	novel	E350*	0.05
PAAD	chr15	43745048	5'Flank	novel		0.18
PAAD	chr15	43766874	Missense_Mutation	novel	A331D	0.04
PAAD	chr15	43770295	Missense_Mutation	NA	A438T	0.18
PRAD	chr15	43771206	Missense_Mutation	novel	Q502H	0.42
READ	chr15	43768536	Missense_Mutation	novel	G359A	0.08
READ	chr15	43766911	Splice_Site	novel	X343_splice	0.27
READ	chr15	43756718	Missense_Mutation	rs779107688	F106L	0.76
READ	chr15	43766908	Missense_Mutation	novel	F342L	0.04
READ	chr15	43772947	3'UTR	novel		0.41
READ	chr15	43773100	3'UTR	rs745711018		0.13
SARC	chr15	43744191	5'Flank	novel		0.52
SKCM	chr15	43773039	3'UTR	novel		0.36
SKCM	chr15	43761452	Silent	NA	Q131Q	0.2
SKCM	chr15	43770270	Silent	rs371186647	I429I	0.22
SKCM	chr15	43771194	Missense_Mutation	NA	K498N	0.15
SKCM	chr15	43761422	Splice_Site	novel	X122_splice	0.26
SKCM	chr15	43761494	Silent	NA	F145F	0.2
SKCM	chr15	43756689	Missense_Mutation	NA	G96E	0.08
SKCM	chr15	43770295	Missense_Mutation	NA	A438T	0.28
SKCM	chr15	43763115	Missense_Mutation	NA	F171L	0.24
STAD	chr15	43744095	5'Flank	novel		0.33
STAD	chr15	43746669	Missense_Mutation	novel	S44P	0.18
STAD	chr15	43744108	5'Flank	novel		0.11
STAD	chr15	43756752	Missense_Mutation	NA	G117V	0.42
STAD	chr15	43744292	5'Flank	novel		0.37
STAD	chr15	43744174	5'Flank	novel		0.55
STAD	chr15	43744559	5'Flank	novel		0.17
STAD	chr15	43745066	5'Flank	novel		0.42
STAD	chr15	43771266	3'UTR	novel		0.42
STAD	chr15	43766753	Missense_Mutation	novel	L291M	0.21
THCA	chr15	43771213	Frame_Shift_Ins	novel	*L505Qfs50**	0.07
UCEC	chr15	43744146	5'Flank	novel		0.39
UCEC	chr15	43768490	Missense_Mutation	rs757380536	R344C	0.36
UCEC	chr15	43744318	5'Flank	novel		0.22
UCEC	chr15	43770327	Splice_Region	novel	R448R	0.27
UCEC	chr15	43766727	Splice_Site	novel	X282_splice	0.03
UCEC	chr15	43763152	Missense_Mutation	rs759578661	R183Q	0.34
UCEC	chr15	43753862	Missense_Mutation	novel	A69D	0.42
UCEC	chr15	43745111	5'Flank	novel		0.24
UCEC	chr15	43743973	5'Flank	novel		0.38
UCEC	chr15	43746612	Missense_Mutation	novel	S25P	0.54
UCEC	chr15	43744108	5'Flank	novel		0.11
UCEC	chr15	43766908	Missense_Mutation	novel	F342L	0.33
UCEC	chr15	43744516	5'Flank	rs540188450		0.44
UCEC	chr15	43769530	Nonsense_Mutation	NA	E384*	0.44
UCEC	chr15	43745082	5'Flank	novel		0.29
UCEC	chr15	43771493	3'UTR	novel		0.41
UCEC	chr15	43751689	Intron	novel		0.4
UCEC	chr15	43745045	5'Flank	novel		0.45
UCEC	chr15	43773045	3'UTR	novel		0.39
UCEC	chr15	43744174	5'Flank	novel		0.81
UCEC	chr15	43769632	Nonsense_Mutation	novel	E418*	0.5
UCEC	chr15	43745088	5'Flank	novel		0.36
UCEC	chr15	43756704	Missense_Mutation	novel	P101Q	0.34
UCEC	chr15	43765467	Missense_Mutation	rs113762568	R207H	0.1
UCEC	chr15	43768490	Missense_Mutation	rs757380536	R344C	0.31
UCEC	chr15	43773030	3'UTR	rs544800114		0.48
UCEC	chr15	43772797	3'UTR	novel		0.29
UCEC	chr15	43745093	5'Flank	novel		0.34
UCEC	chr15	43751590	Intron	novel		0.27
UCEC	chr15	43763120	Frame_Shift_Del	novel	*A174Qfs5**	0.36
UCEC	chr15	43765947	Silent	novel	L260L	0.26
UCEC	chr15	43770255	Frame_Shift_Ins	novel	*D426Rfs15**	0.37
UCEC	chr15	43765533	Missense_Mutation	novel	S229N	0.07
UCEC	chr15	43765541	Missense_Mutation	NA	I232F	0.33
UCEC	chr15	43753874	Missense_Mutation	novel	R73I	0.61
UCEC	chr15	43771188	Missense_Mutation	NA	K496N	0.56
UCEC	chr15	43763120	Frame_Shift_Del	novel	*A174Qfs5**	0.48
UCEC	chr15	43765539	Missense_Mutation	novel	K231T	0.05
UCEC	chr15	43772677	3'UTR	novel		0.63
UCEC	chr15	43765520	Frame_Shift_Ins	NA	*M227Nfs7**	0.31
UCEC	chr15	43771239	3'UTR	novel		0.45
UCEC	chr15	43745171	5'Flank	NA		0.05
UCEC	chr15	43745097	5'Flank	novel		0.05
UCEC	chr15	43753841	Missense_Mutation	novel	R62K	0.36
UCEC	chr15	43771335	3'UTR	novel		0.38
UCEC	chr15	43772880	3'UTR	novel		0.2
UCEC	chr15	43744260	5'Flank	novel		0.4
UCEC	chr15	43753861	Missense_Mutation	NA	A69T	0.32
UCEC	chr15	43765508	Missense_Mutation	novel	A221T	0.31
UCEC	chr15	43770286	Missense_Mutation	novel	D435Y	0.36
UCEC	chr15	43771470	3'UTR	novel		0.17
UCS	chr15	43756693	Silent	novel	V97V	0.37
UCS	chr15	43744187	5'Flank	novel		0.21

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.2222	0.079424
CESC	DEL	0.1864	0.00049652
COAD	DEL	0.3437	2.3878e-07
GBM	DEL	0.208	3.453e-12
HNSC	DEL	0.1628	0.11567
KICH	AMP	0.2576	0.21756
KIRP	DEL	0.1076	0.2062
LUAD	DEL	0.3818	6.8561e-07
MESO	DEL	0.2759	4.5411e-10
PAAD	DEL	0.125	0.13216
READ	DEL	0.4424	0.025797
SARC	DEL	0.1829	0.18974
UCEC	DEL	0.2301	7.1012e-08

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0067	Kaplan-Meier Survival Analysis
HNSC	0.00066	Kaplan-Meier Survival Analysis
SKCM	0.011	Kaplan-Meier Survival Analysis
KIRP	0.0013	Kaplan-Meier Survival Analysis
PAAD	0.013	Kaplan-Meier Survival Analysis
CESC	0.0014	Kaplan-Meier Survival Analysis
LAML	0.049	Kaplan-Meier Survival Analysis
KICH	0.024	Kaplan-Meier Survival Analysis
UCEC	0.00018	Kaplan-Meier Survival Analysis
GBM	0.005	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
UVM	0.00016	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000167004 (Gene tree)
Gene ID: 2923
Gene Symbol: PDIA3
Alias: P58|ERp61|ERp57|ERp60|GRP57|PI-PLC|HsT17083|GRP58
Full Name: protein disulfide isomerase family A member 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 26,888 bases
Position: chr15:43,746,392-43,773,279
Accession: 4606
RBP type: non-canonical RBP
Summary: This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates. [provided by RefSeq, Dec 2016]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
18370413	Proteomic analysis of diaminochlorotriazine adducts in wistar rat pituitary glands and LbetaT2 rat pituitary cells.	Chem Res Toxicol	2008 Apr	Dooley GP	doi: 10.1021/tx700386f
24823364	Identification of miR-494 direct targets involved in senescence of human diploid fibroblasts.	FASEB J	2014 Aug	Comegna M	doi: 10.1096/fj.13-239129
23791840	Superoxide dismutase 1 overexpression in mice abolishes maternal diabetes-induced endoplasmic reticulum stress indiabetic embryopathy.	Am J Obstet Gynecol	2013 Oct	Wang F	doi: 10.1016/j.ajog.2013.06.037

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000446523	PDIA3-203	596	-	ENSP00000391111	75 (aa)	-	F8WBW5
ENST00000300289	PDIA3-201	3727	-	ENSP00000300289	505 (aa)	-	P30101
ENST00000455250	PDIA3-204	725	-	ENSP00000389906	123 (aa)	-	H7BZJ3
ENST00000497349	PDIA3-206	739	-	-	- (aa)	-	-
ENST00000434494	PDIA3-202	2107	-	ENSP00000398005	71 (aa)	-	F8WBS6
ENST00000469684	PDIA3-205	374	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000167004's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04141	Protein processing in endoplasmic reticulum	KEGG
hsa04612	Antigen processing and presentation	KEGG
hsa05163	Human cytomegalovirus infection	KEGG
hsa05168	Herpes simplex virus 1 infection	KEGG
hsa05169	Epstein-Barr virus infection	KEGG
hsa05170	Human immunodeficiency virus 1 infection	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000167004	Platelet Count	5.118e-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000167004	rs3087657	15	43771661	A	Self-reported math ability (MTAG)	30038396	[0.0082-0.016] unit decrease	0.0121	EFO_0004875

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000167004's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000167004	PDIA3	100	93.069	ENSMUSG00000027248	Pdia3	100	93.069	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	-	TAS	Process
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	-	TAS	Process
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0003756	protein disulfide isomerase activity	21873635.	IBA	Function
GO:0004197	cysteine-type endopeptidase activity	9399589.	TAS	Function
GO:0004629	phospholipase C activity	3398923.	TAS	Function
GO:0005515	protein binding	15896298.16905107.17055437.17170699.17947644.20802462.21057456.21670307.21941299.22665516.23826168.26496610.	IPI	Function
GO:0005615	extracellular space	19995400.	IDA	Component
GO:0005634	nucleus	21630459.	HDA	Component
GO:0005783	endoplasmic reticulum	21873635.	IBA	Component
GO:0005783	endoplasmic reticulum	23826168.	IDA	Component
GO:0005783	endoplasmic reticulum	16130169.	TAS	Component
GO:0005788	endoplasmic reticulum lumen	-	TAS	Component
GO:0005925	focal adhesion	21423176.	HDA	Component
GO:0006457	protein folding	21873635.	IBA	Process
GO:0006457	protein folding	-	TAS	Process
GO:0006508	proteolysis	-	IEA	Process
GO:0009986	cell surface	21873635.	IBA	Component
GO:0009986	cell surface	19995400.	IDA	Component
GO:0015036	disulfide oxidoreductase activity	22013210.	TAS	Function
GO:0015037	peptide disulfide oxidoreductase activity	16677074.	IDA	Function
GO:0034975	protein folding in endoplasmic reticulum	22013210.	TAS	Process
GO:0034976	response to endoplasmic reticulum stress	21873635.	IBA	Process
GO:0042470	melanosome	-	IEA	Component
GO:0042802	identical protein binding	16905107.	IPI	Function
GO:0042824	MHC class I peptide loading complex	17947644.21263072.	IDA	Component
GO:0045335	phagocytic vesicle	-	TAS	Component
GO:0045454	cell redox homeostasis	-	IEA	Process
GO:0055038	recycling endosome membrane	-	TAS	Component
GO:0055114	oxidation-reduction process	-	IEA	Process
GO:0070062	extracellular exosome	19199708.	HDA	Component
GO:0098761	cellular response to interleukin-7	-	IEA	Process
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	-	IEA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.