EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
21387291	The novel lupus antigen related protein acheron enhances the development of human breast cancer.	Int J Cancer	2012 Feb 1	Shao R	doi: 10.1002/ijc.26015

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr15	70836343	Missense_Mutation	novel	R121S	0.12	La
BLCA	chr15	70832560	Missense_Mutation	novel	R323T	0.08
BLCA	chr15	70832856	Silent	novel	F224F	0.28
BRCA	chr15	70832994	Silent	rs766611090	N178N	0.12
BRCA	chr15	70836321	Missense_Mutation	rs147847290	V129I	0.31	La
BRCA	chr15	70832982	Silent	novel	P182P	0.25
BRCA	chr15	70832816	Missense_Mutation	novel	E238Q	0.09
BRCA	chr15	70832470	Missense_Mutation	novel	R353Q	0.29
BRCA	chr15	70836369	Missense_Mutation	rs771366776	A113T	0.46	La
CESC	chr15	70832837	Missense_Mutation	novel	R231W	0.46
CESC	chr15	70836325	Silent	NA	V127V	0.11
CESC	chr15	70836390	Missense_Mutation	NA	D106H	0.15	La
CESC	chr15	70836483	Missense_Mutation	NA	E75K	0.13
CESC	chr15	70836451	Nonsense_Mutation	NA	W85*	0.27
CESC	chr15	70832255	Missense_Mutation	rs765085044	V425I	0.11
CHOL	chr15	70832695	Missense_Mutation	novel	T278I	0.17
COAD	chr15	70836362	Frame_Shift_Del	novel	*L115Cfs2**	0.08	La
COAD	chr15	70853961	Missense_Mutation	novel	A43V	0.14
COAD	chr15	70853991	Missense_Mutation	novel	D33G	0.46
COAD	chr15	70832318	Silent	novel	L404L	0.1
COAD	chr15	70832279	Missense_Mutation	novel	M417V	0.38
COAD	chr15	70832132	Missense_Mutation	rs201700915	V466I	0.23
COAD	chr15	70832111	Missense_Mutation	NA	R473G	0.27
COAD	chr15	70832221	Missense_Mutation	rs372104696	R436H	0.66
COAD	chr15	70832283	Silent	NA	K415K	0.26
COAD	chr15	70832355	Silent	novel	G391G	0.15
COAD	chr15	70832354	Missense_Mutation	rs561519879	V392I	0.44
COAD	chr15	70851521	Intron	novel		0.32
COAD	chr15	70851617	Intron	rs776747923		0.44
COAD	chr15	70831900	3'UTR	novel		0.43
COAD	chr15	70831964	3'UTR	novel		0.21
COAD	chr15	70832919	Silent	rs766327224	P203P	0.37
ESCA	chr15	70836478	Silent	rs138869907	N76N	0.48
ESCA	chr15	70832752	Missense_Mutation	novel	A259V	0.26
GBM	chr15	70836406	Silent	rs760707940	I100I	0.39
GBM	chr15	70832566	Missense_Mutation	novel	N321I	0.05
GBM	chr15	70833083	Missense_Mutation	novel	A149S	0.33	La
GBM	chr15	70832935	Missense_Mutation	novel	W198S	0.32
GBM	chr15	70833035	Missense_Mutation	NA	R165W	0.08
GBM	chr15	70833038	Missense_Mutation	novel	H164D	0.05
GBM	chr15	70832860	Missense_Mutation	novel	T223S	0.16
GBM	chr15	70836399	Missense_Mutation	novel	Y103N	0.1	La
GBM	chr15	70836373	Frame_Shift_Ins	novel	*K111Nfs7**	0.03	La
GBM	chr15	70832906	Missense_Mutation	novel	R208W	0.43
HNSC	chr15	70833082	Missense_Mutation	novel	A149E	0.35	La
HNSC	chr15	70832738	Missense_Mutation	novel	E264K	0.22
HNSC	chr15	70832008	3'UTR	rs377477264		0.22
HNSC	chr15	70832238	In_Frame_Del	novel	S424_S430del	0.05
HNSC	chr15	70832115	Missense_Mutation	novel	L471F	0.22
HNSC	chr15	70832225	Missense_Mutation	novel	R435W	0.34
HNSC	chr15	70832439	Silent	novel	P363P	0.19
KIRC	chr15	70832070	Missense_Mutation	NA	R486S	0.21
KIRP	chr15	70836487	Silent	NA	G73G	0.33
LGG	chr15	70832753	Missense_Mutation	rs761513596	A259T	0.34
LGG	chr15	70832964	Silent	novel	V188V	0.16
LIHC	chr15	70832183	Missense_Mutation	novel	G449S	0.35
LIHC	chr15	70832348	Nonsense_Mutation	novel	R394*	0.59
LIHC	chr15	70832503	Missense_Mutation	novel	P342L	0.18
LUAD	chr15	70836441	Missense_Mutation	novel	D89Y	0.4
LUAD	chr15	70832769	Silent	novel	V253V	0.11
LUAD	chr15	70836474	Missense_Mutation	rs778158575	R78C	0.1
LUAD	chr15	70832921	Missense_Mutation	NA	P203T	0.12
LUAD	chr15	70836417	Missense_Mutation	novel	V97M	0.25	La
LUAD	chr15	70836418	Silent	rs753751147	L96L	0.26
LUAD	chr15	70833011	Missense_Mutation	novel	V173F	0.23
LUAD	chr15	70833117	Splice_Site	novel	X138_splice	0.08
LUAD	chr15	70832475	Silent	rs148356697	A351A	0.19
LUAD	chr15	70832736	Silent	NA	E264E	0.29
LUSC	chr15	70832897	Missense_Mutation	novel	E211Q	0.68
LUSC	chr15	70832382	Nonsense_Mutation	NA	W382*	0.1
LUSC	chr15	70836322	Silent	rs141487882	S128S	0.28
LUSC	chr15	70833048	Missense_Mutation	novel	L160F	0.24
OV	chr15	70832015	3'UTR	novel		0.22
OV	chr15	70832511	Silent	novel	S339S	0.05
READ	chr15	70832160	Silent	novel	R456R	0.16
READ	chr15	70831956	3'UTR	novel		0.13
READ	chr15	70832511	Silent	novel	S339S	0.1
READ	chr15	70851640	Intron	rs759180458		0.42
READ	chr15	70832556	Silent	rs752044115	V324V	0.42
READ	chr15	70832739	Silent	rs371562863	F263F	0.49
READ	chr15	70831964	3'UTR	novel		0.46
READ	chr15	70832593	Missense_Mutation	rs770915412	A312V	0.19
SARC	chr15	70832656	Missense_Mutation	novel	I291T	0.28
SKCM	chr15	70836444	Missense_Mutation	novel	P88S	0.75
SKCM	chr15	70831964	3'UTR	novel		0.1
SKCM	chr15	70836376	Silent	NA	E110E	0.45
SKCM	chr15	70851682	Intron	rs181414435		0.38
SKCM	chr15	70832350	Missense_Mutation	NA	S393F	0.49
SKCM	chr15	70832172	Silent	novel	P452P	0.25
SKCM	chr15	70832173	Missense_Mutation	novel	P452L	0.25
SKCM	chr15	70832399	Missense_Mutation	novel	P377S	0.27
SKCM	chr15	70832660	Silent	NA	L290L	0.25
SKCM	chr15	70832836	Missense_Mutation	rs746873492	R231Q	0.33
SKCM	chr15	70832009	3'UTR	novel		0.36
SKCM	chr15	70832134	Missense_Mutation	NA	P465L	0.46
SKCM	chr15	70851720	Intron	novel		0.61
SKCM	chr15	70832009	3'UTR	novel		0.34
SKCM	chr15	70836295	Splice_Region	novel	K137K	0.57
SKCM	chr15	70832363	Missense_Mutation	rs780518378	R389C	0.4
SKCM	chr15	70832009	3'UTR	novel		0.19
SKCM	chr15	70832339	Missense_Mutation	novel	P397S	0.24
STAD	chr15	70832101	Missense_Mutation	NA	D476A	0.28
STAD	chr15	70832602	Missense_Mutation	rs368859399	E309G	0.23
STAD	chr15	70832183	Missense_Mutation	novel	G449S	0.14
STAD	chr15	70832607	Silent	rs760442315	D307D	0.07
STAD	chr15	70832989	Frame_Shift_Del	novel	*N180Tfs34**	0.29
STAD	chr15	70831892	3'UTR	novel		0.27
STAD	chr15	70836442	Silent	rs150115251	P88P	0.22
UCEC	chr15	70851617	Intron	rs776747923		0.18
UCEC	chr15	70831932	3'UTR	novel		0.38
UCEC	chr15	70832607	Silent	rs760442315	D307D	0.28
UCEC	chr15	70831896	3'UTR	rs148320872		0.38
UCEC	chr15	70832608	Missense_Mutation	novel	D307G	0.19
UCEC	chr15	70851711	Intron	novel		0.36
UCEC	chr15	70832317	Missense_Mutation	novel	L404P	0.29
UCEC	chr15	70832051	3'UTR	novel		0.39
UCEC	chr15	70832783	Missense_Mutation	NA	R249S	0.09
UCEC	chr15	70832037	3'UTR	novel		0.31
UCEC	chr15	70851443	Intron	novel		0.28
UCEC	chr15	70832864	Missense_Mutation	rs772667024	G222R	0.19
UCEC	chr15	70851681	Intron	rs755192640		0.09
UCEC	chr15	70851643	Intron	NA		0.39
UCEC	chr15	70836405	Missense_Mutation	novel	E101K	0.07	La
UCEC	chr15	70832222	Missense_Mutation	rs760940752	R436C	0.47
UCEC	chr15	70832867	Missense_Mutation	novel	F221V	0.09
UCEC	chr15	70832423	Missense_Mutation	novel	L369I	0.43
UCEC	chr15	70851589	Intron	novel		0.34
UCEC	chr15	70832806	Frame_Shift_Del	novel	*P241Lfs36**	0.53
UCEC	chr15	70832133	Silent	rs150993636	P465P	0.4
UCEC	chr15	70832739	Silent	rs371562863	F263F	0.4
UCEC	chr15	70832243	Missense_Mutation	novel	G429R	0.3
UCEC	chr15	70832748	Silent	rs776423353	I260I	0.15
UCEC	chr15	70836298	Missense_Mutation	novel	K136N	0.35	La
UCEC	chr15	70832196	Missense_Mutation	novel	Q444H	0.34
UCEC	chr15	70833026	Missense_Mutation	novel	R168W	0.5
UCEC	chr15	70832218	Missense_Mutation	rs772932234	R437H	0.27
UCEC	chr15	70832397	Silent	rs768731269	P377P	0.32
UCEC	chr15	70832000	3'UTR	novel		0.48
UCEC	chr15	70836293	Splice_Site	novel	X137_splice	0.33
UCEC	chr15	70851681	Intron	rs755192640		0.2
UCEC	chr15	70832354	Missense_Mutation	rs561519879	V392I	0.31

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
LGG	AMP	0.0175	0.19963
PAAD	AMP	0.0652	0.20695
PAAD	DEL	0.1033	0.13216

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.008	Kaplan-Meier Survival Analysis
STAD	0.0045	Kaplan-Meier Survival Analysis
MESO	0.00077	Kaplan-Meier Survival Analysis
HNSC	0.035	Kaplan-Meier Survival Analysis
SKCM	0.033	Kaplan-Meier Survival Analysis
PRAD	0.035	Kaplan-Meier Survival Analysis
BRCA	0.008	Kaplan-Meier Survival Analysis
COAD	0.049	Kaplan-Meier Survival Analysis
LAML	0.047	Kaplan-Meier Survival Analysis
UCEC	0.0023	Kaplan-Meier Survival Analysis
CHOL	0.05	Kaplan-Meier Survival Analysis
LUAD	0.011	Kaplan-Meier Survival Analysis
UVM	0.0045	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000166173 (Gene tree)
Gene ID: 55323
Gene Symbol: LARP6
Alias: acheron|FLJ11196
Full Name: La ribonucleoprotein domain family member 6
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 25,136 bases
Position: chr15:70,829,130-70,854,265
Accession: 24012
RBP type: canonical RBP
Summary: (La Ribonucleoprotein Domain Family Member 6) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is LARP1B.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000299213	La	PF05383.17	4e-20	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
25896032	(1)H, (15)N and (13)C chemical shift assignments of the La motif and RRM1 from human LARP6.	Biomol NMR Assign	2015 Oct	Martino L	doi: 10.1007/s12104-015-9605-3
19917293	Binding of LARP6 to the conserved 5' stem-loop regulates translation of mRNAs encoding type I collagen.	J Mol Biol	2010 Jan 15	Cai L	doi: 10.1016/j.jmb.2009.11.020
19481601	Regulation of muscle differentiation and survival by Acheron.	Mech Dev	2009 Aug-Sep	Wang Z	doi: 10.1016/j.mod.2009.05.003
22139627	Acheron regulates vascular endothelial proliferation and angiogenesis together with Id1 during wound healing.	Cell Biochem Funct	2011 Dec	Sun R	doi: 10.1002/cbf.1799
21387291	The novel lupus antigen related protein acheron enhances the development of human breast cancer.	Int J Cancer	2012 Feb 1	Shao R	doi: 10.1002/ijc.26015
20603131	Nonmuscle myosin-dependent synthesis of type I collagen.	J Mol Biol	2010 Aug 27	Cai L	doi: 10.1016/j.jmb.2010.06.057
23148093	The association of a La module with the PABP-interacting motif PAM2 is a recurrent evolutionary process that led to the neofunctionalization of La-related proteins.	RNA	2013 Jan	Merret R	doi: 10.1261/rna.035469.112
25488812	Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.	Nucleic Acids Res	2015 Jan	Martino L	doi: 10.1093/nar/gku1287
25271881	Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane.	PLoS One	2014 Oct 1	Wang H	doi: 10.1371/journal.pone.0108870
26932461	Akt mediated phosphorylation of LARP6; critical step in biosynthesis of type I collagen.	Sci Rep	2016 Mar 2	Zhang Y	doi: 10.1038/srep22597.
28344782	La-related protein 6 controls ciliated cell differentiation.	Cilia	2017 Mar 23	Manojlovic Z	doi: 10.1186/s13630-017-0047-7
27011170	LARP6 Meets Collagen mRNA: Specific Regulation of Type I Collagen Expression.	Int J Mol Sci	2016 Mar 22	Zhang Y	doi: 10.3390/ijms17030419.
28400296	Recombinant expression and purification of the RNA-binding LARP6 proteins from fish genetic model organisms.	Protein Expr Purif	2017 Jun	Castro JM	doi: 10.1016/j.pep.2017.04.004
21728959	Progress towards discovery of antifibrotic drugs targeting synthesis of type I collagen.	Curr Med Chem	2011	Fritz D	-
30674965	Discovery and evaluation of inhibitor of LARP6 as specific antifibrotic compound.	Sci Rep	2019 Jan 23	Stefanovic B	doi: 10.1038/s41598-018-36841-y.
30901265	Technology for Discovery of Antifibrotic Drugs: Phenotypic Screening for LARP6 Inhibitors Using Inverted Yeast Three Hybrid System.	Assay Drug Dev Technol	2019 Apr	Stefanovic L	doi: 10.1089/adt.2018.904

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000299213	LARP6-201	4469	-	ENSP00000299213	491 (aa)	-	Q9BRS8
ENST00000560052	LARP6-205	473	-	-	- (aa)	-	-
ENST00000559316	LARP6-204	558	-	ENSP00000467334	31 (aa)	-	K7EPD2
ENST00000559140	LARP6-203	964	-	ENSP00000453551	78 (aa)	-	H0YMC6
ENST00000344870	LARP6-202	527	-	ENSP00000343869	93 (aa)	-	Q9BRS8

Gene Model

Click here to download ENSG00000166173's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000166173's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000166173	LARP6	95	56.612	ENSAPOG00000021773	larp6a	63	59.101	Acanthochromis_polyacanthus
ENSG00000166173	LARP6	100	93.548	ENSAMEG00000008897	LARP6	100	92.523	Ailuropoda_melanoleuca
ENSG00000166173	LARP6	95	57.231	ENSACIG00000005166	larp6a	86	59.551	Amphilophus_citrinellus
ENSG00000166173	LARP6	95	56.612	ENSAOCG00000002284	larp6a	63	59.101	Amphiprion_ocellaris
ENSG00000166173	LARP6	95	56.612	ENSAPEG00000008077	larp6a	84	59.101	Amphiprion_percula
ENSG00000166173	LARP6	95	56.405	ENSATEG00000004018	larp6a	62	58.876	Anabas_testudineus
ENSG00000166173	LARP6	85	71.395	ENSAPLG00000009914	LARP6	99	71.395	Anas_platyrhynchos
ENSG00000166173	LARP6	84	68.029	ENSACAG00000008613	LARP6	98	68.029	Anolis_carolinensis
ENSG00000166173	LARP6	100	100.000	ENSANAG00000024860	LARP6	100	98.778	Aotus_nancymaae
ENSG00000166173	LARP6	95	57.025	ENSACLG00000018561	larp6a	61	59.326	Astatotilapia_calliptera
ENSG00000166173	LARP6	90	57.081	ENSAMXG00000029387	larp6a	68	57.895	Astyanax_mexicanus
ENSG00000166173	LARP6	83	41.019	ENSAMXG00000036816	-	93	40.920	Astyanax_mexicanus
ENSG00000166173	LARP6	100	100.000	ENSBTAG00000003915	LARP6	100	92.683	Bos_taurus
ENSG00000166173	LARP6	100	100.000	ENSCJAG00000018642	-	100	98.574	Callithrix_jacchus
ENSG00000166173	LARP6	100	100.000	ENSCJAG00000046236	-	100	97.963	Callithrix_jacchus
ENSG00000166173	LARP6	100	93.548	ENSCAFG00000017616	LARP6	99	94.118	Canis_familiaris
ENSG00000166173	LARP6	100	93.548	ENSCAFG00020007296	LARP6	100	92.480	Canis_lupus_dingo
ENSG00000166173	LARP6	100	100.000	ENSCHIG00000013742	LARP6	100	92.480	Capra_hircus
ENSG00000166173	LARP6	100	96.774	ENSTSYG00000028124	LARP6	87	93.882	Carlito_syrichta
ENSG00000166173	LARP6	100	90.323	ENSCAPG00000015452	LARP6	99	91.274	Cavia_aperea
ENSG00000166173	LARP6	100	90.323	ENSCPOG00000022687	LARP6	100	90.061	Cavia_porcellus
ENSG00000166173	LARP6	100	100.000	ENSCCAG00000036320	LARP6	100	98.167	Cebus_capucinus
ENSG00000166173	LARP6	100	100.000	ENSCATG00000042432	LARP6	100	99.185	Cercocebus_atys
ENSG00000166173	LARP6	100	93.548	ENSCLAG00000007893	LARP6	100	92.292	Chinchilla_lanigera
ENSG00000166173	LARP6	100	100.000	ENSCSAG00000013672	LARP6	100	99.389	Chlorocebus_sabaeus
ENSG00000166173	LARP6	100	100.000	ENSCHOG00000003318	LARP6	100	93.096	Choloepus_hoffmanni
ENSG00000166173	LARP6	89	70.023	ENSCPBG00000010771	LARP6	84	70.320	Chrysemys_picta_bellii
ENSG00000166173	LARP6	100	100.000	ENSCANG00000025833	LARP6	100	99.528	Colobus_angolensis_palliatus
ENSG00000166173	LARP6	100	93.548	ENSCGRG00001024472	Larp6	100	90.854	Cricetulus_griseus_chok1gshd
ENSG00000166173	LARP6	100	93.548	ENSCGRG00000004527	Larp6	100	90.854	Cricetulus_griseus_crigri
ENSG00000166173	LARP6	95	56.936	ENSCSEG00000011196	larp6a	65	59.234	Cynoglossus_semilaevis
ENSG00000166173	LARP6	87	58.744	ENSCVAG00000009605	larp6a	65	58.744	Cyprinodon_variegatus
ENSG00000166173	LARP6	87	58.036	ENSDARG00000005355	larp6a	97	61.033	Danio_rerio
ENSG00000166173	LARP6	100	100.000	ENSDNOG00000042993	LARP6	100	92.276	Dasypus_novemcinctus
ENSG00000166173	LARP6	100	80.769	ENSDORG00000023910	Larp6	100	80.162	Dipodomys_ordii
ENSG00000166173	LARP6	100	87.097	ENSETEG00000020390	LARP6	78	90.400	Echinops_telfairi
ENSG00000166173	LARP6	100	100.000	ENSEASG00005005490	LARP6	73	94.715	Equus_asinus_asinus
ENSG00000166173	LARP6	100	100.000	ENSECAG00000014190	LARP6	100	94.512	Equus_caballus
ENSG00000166173	LARP6	87	58.613	ENSELUG00000007341	larp6a	64	58.613	Esox_lucius
ENSG00000166173	LARP6	100	100.000	ENSFCAG00000001361	LARP6	100	92.886	Felis_catus
ENSG00000166173	LARP6	88	68.636	ENSFALG00000012389	LARP6	99	65.625	Ficedula_albicollis
ENSG00000166173	LARP6	100	90.323	ENSFDAG00000019994	LARP6	86	92.500	Fukomys_damarensis
ENSG00000166173	LARP6	87	58.744	ENSFHEG00000010312	larp6a	63	58.744	Fundulus_heteroclitus
ENSG00000166173	LARP6	89	70.588	ENSGALG00000004046	LARP6	94	67.432	Gallus_gallus
ENSG00000166173	LARP6	87	58.969	ENSGAFG00000009426	larp6a	65	58.969	Gambusia_affinis
ENSG00000166173	LARP6	86	59.497	ENSGACG00000014622	larp6a	97	59.497	Gasterosteus_aculeatus
ENSG00000166173	LARP6	90	66.216	ENSGAGG00000010802	LARP6	58	70.707	Gopherus_agassizii
ENSG00000166173	LARP6	100	100.000	ENSGGOG00000024151	LARP6	100	100.000	Gorilla_gorilla
ENSG00000166173	LARP6	95	57.025	ENSHBUG00000021014	larp6a	61	59.326	Haplochromis_burtoni
ENSG00000166173	LARP6	100	93.548	ENSHGLG00000015112	LARP6	100	91.717	Heterocephalus_glaber_female
ENSG00000166173	LARP6	100	93.548	ENSHGLG00100013159	LARP6	100	94.353	Heterocephalus_glaber_male
ENSG00000166173	LARP6	95	55.761	ENSHCOG00000001241	larp6a	84	58.145	Hippocampus_comes
ENSG00000166173	LARP6	85	59.039	ENSIPUG00000010187	larp6	65	60.277	Ictalurus_punctatus
ENSG00000166173	LARP6	90	36.444	ENSIPUG00000002828	-	96	37.333	Ictalurus_punctatus
ENSG00000166173	LARP6	100	93.548	ENSSTOG00000024279	LARP6	98	95.364	Ictidomys_tridecemlineatus
ENSG00000166173	LARP6	100	89.024	ENSJJAG00000011013	Larp6	100	89.024	Jaculus_jaculus
ENSG00000166173	LARP6	87	59.955	ENSKMAG00000001702	larp6a	60	59.955	Kryptolebias_marmoratus
ENSG00000166173	LARP6	95	55.350	ENSLBEG00000000170	larp6a	84	57.271	Labrus_bergylta
ENSG00000166173	LARP6	97	65.208	ENSLACG00000018706	LARP6	90	64.583	Latimeria_chalumnae
ENSG00000166173	LARP6	83	41.805	ENSLACG00000002786	-	96	44.498	Latimeria_chalumnae
ENSG00000166173	LARP6	85	44.131	ENSLOCG00000008547	-	83	44.028	Lepisosteus_oculatus
ENSG00000166173	LARP6	96	59.794	ENSLOCG00000014592	larp6a	69	59.221	Lepisosteus_oculatus
ENSG00000166173	LARP6	100	96.774	ENSLAFG00000016343	LARP6	100	93.065	Loxodonta_africana
ENSG00000166173	LARP6	100	100.000	ENSMFAG00000035507	LARP6	100	99.555	Macaca_fascicularis
ENSG00000166173	LARP6	100	100.000	ENSMMUG00000004429	LARP6	100	96.741	Macaca_mulatta
ENSG00000166173	LARP6	100	100.000	ENSMNEG00000045335	LARP6	100	99.389	Macaca_nemestrina
ENSG00000166173	LARP6	100	100.000	ENSMLEG00000038587	LARP6	100	99.528	Mandrillus_leucophaeus
ENSG00000166173	LARP6	95	56.584	ENSMAMG00000005261	larp6a	62	59.060	Mastacembelus_armatus
ENSG00000166173	LARP6	95	57.025	ENSMZEG00005005774	larp6a	61	59.326	Maylandia_zebra
ENSG00000166173	LARP6	85	71.564	ENSMGAG00000005077	LARP6	99	71.564	Meleagris_gallopavo
ENSG00000166173	LARP6	100	96.774	ENSMAUG00000018486	Larp6	100	90.447	Mesocricetus_auratus
ENSG00000166173	LARP6	100	93.548	ENSMICG00000011234	LARP6	100	92.073	Microcebus_murinus
ENSG00000166173	LARP6	100	96.774	ENSMOCG00000010492	Larp6	100	90.041	Microtus_ochrogaster
ENSG00000166173	LARP6	95	57.557	ENSMMOG00000016284	larp6a	85	60.135	Mola_mola
ENSG00000166173	LARP6	100	77.419	ENSMODG00000009034	LARP6	94	74.120	Monodelphis_domestica
ENSG00000166173	LARP6	95	57.202	ENSMALG00000014439	larp6a	84	59.284	Monopterus_albus
ENSG00000166173	LARP6	100	96.774	MGP_CAROLIEiJ_G0032314	Larp6	98	91.925	Mus_caroli
ENSG00000166173	LARP6	100	96.774	ENSMUSG00000034839	Larp6	100	91.057	Mus_musculus
ENSG00000166173	LARP6	100	96.774	MGP_PahariEiJ_G0015180	Larp6	100	90.244	Mus_pahari
ENSG00000166173	LARP6	100	96.774	MGP_SPRETEiJ_G0033452	Larp6	100	90.854	Mus_spretus
ENSG00000166173	LARP6	100	90.323	ENSMPUG00000017086	LARP6	100	93.224	Mustela_putorius_furo
ENSG00000166173	LARP6	100	94.106	ENSMLUG00000010319	LARP6	100	94.106	Myotis_lucifugus
ENSG00000166173	LARP6	100	96.774	ENSNGAG00000014238	Larp6	100	89.634	Nannospalax_galili
ENSG00000166173	LARP6	95	57.025	ENSNBRG00000008120	larp6a	84	59.326	Neolamprologus_brichardi
ENSG00000166173	LARP6	100	100.000	ENSNLEG00000013691	LARP6	100	99.185	Nomascus_leucogenys
ENSG00000166173	LARP6	100	77.419	ENSMEUG00000002270	LARP6	98	65.638	Notamacropus_eugenii
ENSG00000166173	LARP6	71	80.912	ENSOPRG00000004868	-	99	80.912	Ochotona_princeps
ENSG00000166173	LARP6	100	90.323	ENSODEG00000015958	LARP6	100	87.627	Octodon_degus
ENSG00000166173	LARP6	95	56.996	ENSONIG00000002901	larp6a	84	59.284	Oreochromis_niloticus
ENSG00000166173	LARP6	100	96.774	ENSOCUG00000009306	LARP6	99	83.452	Oryctolagus_cuniculus
ENSG00000166173	LARP6	95	57.231	ENSORLG00000014256	larp6a	86	59.685	Oryzias_latipes
ENSG00000166173	LARP6	95	57.231	ENSORLG00020019657	larp6a	63	59.685	Oryzias_latipes_hni
ENSG00000166173	LARP6	95	57.231	ENSORLG00015017915	larp6a	63	59.685	Oryzias_latipes_hsok
ENSG00000166173	LARP6	95	57.645	ENSOMEG00000017049	larp6a	63	60.135	Oryzias_melastigma
ENSG00000166173	LARP6	100	92.480	ENSOGAG00000000522	LARP6	100	92.480	Otolemur_garnettii
ENSG00000166173	LARP6	100	100.000	ENSOARG00000018750	LARP6	99	92.290	Ovis_aries
ENSG00000166173	LARP6	100	100.000	ENSPPAG00000031247	LARP6	100	100.000	Pan_paniscus
ENSG00000166173	LARP6	100	100.000	ENSPPRG00000011282	LARP6	100	92.276	Panthera_pardus
ENSG00000166173	LARP6	100	100.000	ENSPTIG00000015318	LARP6	86	93.412	Panthera_tigris_altaica
ENSG00000166173	LARP6	100	100.000	ENSPTRG00000007234	LARP6	100	100.000	Pan_troglodytes
ENSG00000166173	LARP6	100	100.000	ENSPANG00000016362	LARP6	100	99.389	Papio_anubis
ENSG00000166173	LARP6	96	56.619	ENSPKIG00000004511	LARP6	65	58.222	Paramormyrops_kingsleyae
ENSG00000166173	LARP6	96	59.375	ENSPKIG00000020103	larp6a	84	61.348	Paramormyrops_kingsleyae
ENSG00000166173	LARP6	62	80.769	ENSPSIG00000009071	LARP6	91	74.783	Pelodiscus_sinensis
ENSG00000166173	LARP6	95	57.645	ENSPMGG00000006958	larp6a	86	60.225	Periophthalmus_magnuspinnatus
ENSG00000166173	LARP6	100	90.854	ENSPEMG00000012909	Larp6	100	90.854	Peromyscus_maniculatus_bairdii
ENSG00000166173	LARP6	100	77.419	ENSPCIG00000020765	LARP6	94	75.569	Phascolarctos_cinereus
ENSG00000166173	LARP6	87	59.598	ENSPFOG00000014175	larp6a	84	59.598	Poecilia_formosa
ENSG00000166173	LARP6	87	59.641	ENSPLAG00000011105	larp6a	62	59.641	Poecilia_latipinna
ENSG00000166173	LARP6	87	59.417	ENSPMEG00000011085	larp6a	63	59.417	Poecilia_mexicana
ENSG00000166173	LARP6	87	59.193	ENSPREG00000008067	larp6a	63	59.193	Poecilia_reticulata
ENSG00000166173	LARP6	100	100.000	ENSPPYG00000006604	LARP6	100	99.593	Pongo_abelii
ENSG00000166173	LARP6	100	87.097	ENSPCAG00000014197	LARP6	76	93.333	Procavia_capensis
ENSG00000166173	LARP6	100	96.774	ENSPCOG00000022934	LARP6	100	92.480	Propithecus_coquereli
ENSG00000166173	LARP6	100	93.496	ENSPVAG00000005618	LARP6	100	93.496	Pteropus_vampyrus
ENSG00000166173	LARP6	95	57.025	ENSPNYG00000009835	larp6a	84	59.326	Pundamilia_nyererei
ENSG00000166173	LARP6	87	57.494	ENSPNAG00000017966	larp6a	72	58.389	Pygocentrus_nattereri
ENSG00000166173	LARP6	100	90.323	ENSRNOG00000012438	Larp6	100	89.634	Rattus_norvegicus
ENSG00000166173	LARP6	100	100.000	ENSRBIG00000032902	LARP6	99	95.297	Rhinopithecus_bieti
ENSG00000166173	LARP6	100	100.000	ENSRROG00000043074	LARP6	99	99.174	Rhinopithecus_roxellana
ENSG00000166173	LARP6	100	100.000	ENSSBOG00000024190	LARP6	100	98.585	Saimiri_boliviensis_boliviensis
ENSG00000166173	LARP6	100	77.419	ENSSHAG00000018495	LARP6	100	75.701	Sarcophilus_harrisii
ENSG00000166173	LARP6	95	51.782	ENSSFOG00015002254	LARP6	91	52.321	Scleropages_formosus
ENSG00000166173	LARP6	85	59.584	ENSSFOG00015023268	larp6a	82	61.972	Scleropages_formosus
ENSG00000166173	LARP6	95	57.350	ENSSMAG00000009953	larp6a	62	59.910	Scophthalmus_maximus
ENSG00000166173	LARP6	95	57.113	ENSSDUG00000007438	larp6a	62	59.641	Seriola_dumerili
ENSG00000166173	LARP6	95	57.113	ENSSLDG00000016647	larp6a	62	59.641	Seriola_lalandi_dorsalis
ENSG00000166173	LARP6	86	71.564	ENSSPUG00000011312	LARP6	99	71.564	Sphenodon_punctatus
ENSG00000166173	LARP6	95	56.612	ENSSPAG00000020502	larp6a	62	59.101	Stegastes_partitus
ENSG00000166173	LARP6	100	100.000	ENSSSCG00000004974	LARP6	100	93.496	Sus_scrofa
ENSG00000166173	LARP6	85	69.905	ENSTGUG00000005808	LARP6	99	69.905	Taeniopygia_guttata
ENSG00000166173	LARP6	95	57.407	ENSTRUG00000003151	larp6a	65	59.465	Takifugu_rubripes
ENSG00000166173	LARP6	95	56.133	ENSTNIG00000011926	larp6a	88	58.124	Tetraodon_nigroviridis
ENSG00000166173	LARP6	100	87.097	ENSTBEG00000015077	LARP6	99	92.417	Tupaia_belangeri
ENSG00000166173	LARP6	100	90.323	ENSUAMG00000010467	LARP6	89	87.611	Ursus_americanus
ENSG00000166173	LARP6	100	93.548	ENSVVUG00000015227	LARP6	99	90.244	Vulpes_vulpes
ENSG00000166173	LARP6	96	66.597	ENSXETG00000020340	larp6	88	69.794	Xenopus_tropicalis
ENSG00000166173	LARP6	87	59.193	ENSXCOG00000012654	larp6a	89	59.193	Xiphophorus_couchianus
ENSG00000166173	LARP6	87	59.193	ENSXMAG00000021015	larp6a	60	59.193	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	20603131.21746880.22190748.	IPI	Function
GO:0005634	nucleus	21746880.	IDA	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0005844	polysome	20603131.22190748.	IDA	Component
GO:0005844	polysome	21746880.	IMP	Component
GO:0006396	RNA processing	-	IEA	Process
GO:0017022	myosin binding	20603131.	IPI	Function
GO:0032967	positive regulation of collagen biosynthetic process	21746880.	IMP	Process
GO:0035613	RNA stem-loop binding	20603131.	IDA	Function
GO:0035613	RNA stem-loop binding	21746880.	IMP	Function
GO:0045727	positive regulation of translation	21746880.	IMP	Process
GO:0048027	mRNA 5'-UTR binding	20603131.22190748.	IDA	Function
GO:0048027	mRNA 5'-UTR binding	21746880.	IMP	Function
GO:1902416	positive regulation of mRNA binding	22190748.	IDA	Process
GO:1902416	positive regulation of mRNA binding	21746880.	IMP	Process
GO:1990825	sequence-specific mRNA binding	22190748.	IDA	Function
GO:1990904	ribonucleoprotein complex	22190748.	IDA	Component
GO:1990904	ribonucleoprotein complex	21746880.	IMP	Component

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.