EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
17893231	Phosphoinositol phosphatase SHIP2 promotes cancer development and metastasis coupled with alterations in EGF receptor turnover.	Carcinogenesis	2008 Jan	Prasad NK	-
27716613	Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation.	Oncotarget	2016 Nov 8	Hoekstra E	doi: 10.18632/oncotarget.12321.
24133597	Elevated expression of SHIP2 correlates with poor prognosis in non-small cell lung cancer.	Int J Clin Exp Pathol	2013 Sep 15	Fu M	-
24802135	A novel oncogenic role of inositol phosphatase SHIP2 in ER-negative breast cancer stem cells: involvement of JNK/vimentin activation.	Stem Cells	2014 Aug	Fu CH	doi: 10.1002/stem.1735.
26201869	Suppression of SHIP2 contributes to tumorigenesis and proliferation of gastric cancer cells via activation of Akt.	J Gastroenterol	2016 Mar	Ye Y	doi: 10.1007/s00535-015-1101-0
19065064	High expression of obesity-linked phosphatase SHIP2 in invasive breast cancer correlates with reduced disease-free survival.	Tumour Biol	2008	Prasad NK	doi: 10.1159/000172970
25525286	High SHIP2 expression indicates poor survival in colorectal cancer.	Dis Markers	2014	Yang J	doi: 10.1155/2014/218968
24091101	SHIP2 signaling in normal and pathological situations: Its impact on cell proliferation.	Adv Biol Regul	2014 Jan	Elong Edimo W	doi: 10.1016/j.jbior.2013.09.002
27597754	5'-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion.	J Cell Biol	2016 Sep 12	Rajadurai CV	doi: 10.1083/jcb.201501003
28117748	Decreased Sp1 Expression Mediates Downregulation of SHIP2 in Gastric Cancer Cells.	Int J Mol Sci	2017 Jan 22	Ye Y	doi: 10.3390/ijms18010220.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr11	72228398	Silent	rs754321111	I99I	0.46
BLCA	chr11	72228140	Intron	novel		0.54
BLCA	chr11	72228253	Splice_Region	novel	Q82Q	0.3
BLCA	chr11	72238071	Silent	NA	S1194S	0.14
BLCA	chr11	72230196	Missense_Mutation	novel	E339Q	0.43
BLCA	chr11	72235327	Silent	rs375358684	I845I	0.11
BLCA	chr11	72237494	Missense_Mutation	novel	E1084K	0.12
BLCA	chr11	72235421	Missense_Mutation	novel	E877Q	0.45
BLCA	chr11	72235904	Missense_Mutation	novel	E933Q	0.5
BLCA	chr11	72238171	Missense_Mutation	novel	L1228I	0.48
BLCA	chr11	72235315	Silent	NA	L841L	0.17
BLCA	chr11	72238113	Missense_Mutation	NA	I1208M	0.12
BLCA	chr11	72238060	Missense_Mutation	NA	G1191W	0.54
BLCA	chr11	72231602	Silent	rs570236237	I534I	0.27
BLCA	chr11	72237672	Missense_Mutation	novel	S1143L	0.54
BLCA	chr11	72230269	Missense_Mutation	novel	R363L	0.39
BLCA	chr11	72230393	Silent	novel	Q374Q	0.13
BLCA	chr11	72237220	Silent	novel	V992V	0.04
BLCA	chr11	72231036	Silent	novel	S448S	0.14
BLCA	chr11	72235134	Missense_Mutation	novel	D812H	0.36
BLCA	chr11	72232307	Silent	NA	H561H	0.36
BRCA	chr11	72238372	3'UTR	novel		0.11
BRCA	chr11	72232683	Silent	novel	L590L	0.18
BRCA	chr11	72233509	Silent	novel	I703I	0.25
BRCA	chr11	72228738	Missense_Mutation	novel	E137K	0.07
BRCA	chr11	72229736	Nonsense_Mutation	NA	S276*	0.4
BRCA	chr11	72232305	Missense_Mutation	novel	H561Y	0.58	Exo_endo_phos
BRCA	chr11	72232260	Missense_Mutation	rs376117918	V546I	0.25	Exo_endo_phos
BRCA	chr11	72228378	Nonsense_Mutation	NA	Q93*	0.26
BRCA	chr11	72229200	Missense_Mutation	novel	T210N	0.08
BRCA	chr11	72231100	Missense_Mutation	NA	G470R	0.38	Exo_endo_phos
BRCA	chr11	72238045	Missense_Mutation	NA	P1186T	0.19
BRCA	chr11	72230812	Missense_Mutation	NA	C405Y	0.52
BRCA	chr11	72231151	Frame_Shift_Del	NA	*G488Afs43**	0.3	Exo_endo_phos
CESC	chr11	72230017	Missense_Mutation	NA	E313K	0.43
CESC	chr11	72230018	Missense_Mutation	NA	E313V	0.43
CESC	chr11	72233138	Missense_Mutation	NA	A672G	0.39	Exo_endo_phos
CESC	chr11	72230439	Missense_Mutation	rs771324555	R390C	0.41
CESC	chr11	72231507	Nonsense_Mutation	novel	Q503*	0.37	Exo_endo_phos
CESC	chr11	72233116	Missense_Mutation	rs201836862	R665W	0.33	Exo_endo_phos
CESC	chr11	72239072	3'UTR	novel		0.6
CESC	chr11	72233736	Missense_Mutation	NA	S735F	0.36
CHOL	chr11	72228373	Missense_Mutation	rs142516692	R91H	0.11
COAD	chr11	72237194	Missense_Mutation	NA	P984T	0.31
COAD	chr11	72237170	Missense_Mutation	novel	P976S	0.52
COAD	chr11	72235856	Missense_Mutation	rs780472220	R917C	0.44
COAD	chr11	72232680	Silent	NA	Q589Q	0.21
COAD	chr11	72233666	Missense_Mutation	novel	D712N	0.23	Exo_endo_phos
COAD	chr11	72238422	3'UTR	novel		0.22
COAD	chr11	72237164	Frame_Shift_Ins	rs749079348	*P977Tfs7**	0.5
COAD	chr11	72228470	Silent	novel	P123P	0.33
COAD	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.3
COAD	chr11	72230430	Missense_Mutation	rs778197564	R387W	0.07
COAD	chr11	72228211	Silent	novel	T68T	0.32
COAD	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.54
COAD	chr11	72232705	Missense_Mutation	rs753557940	R598C	0.42	Exo_endo_phos
COAD	chr11	72228758	Silent	NA	P143P	0.38
COAD	chr11	72235419	Missense_Mutation	rs367743824	T876M	0.36
COAD	chr11	72232660	Missense_Mutation	NA	L583F	0.38	Exo_endo_phos
COAD	chr11	72230439	Missense_Mutation	rs771324555	R390C	0.06
COAD	chr11	72230206	Missense_Mutation	rs774794017	R342Q	0.14
COAD	chr11	72235734	Nonsense_Mutation	rs781674896	R907*	0.33
COAD	chr11	72232919	Silent	novel	L632L	0.1
COAD	chr11	72235379	Missense_Mutation	novel	T863A	0.32
COAD	chr11	72231129	Silent	rs201505175	R479R	0.27
COAD	chr11	72228462	Nonsense_Mutation	NA	R121*	0.38
COAD	chr11	72237164	Missense_Mutation	NA	A974P	0.28
COAD	chr11	72237270	Missense_Mutation	novel	V1009A	0.1
COAD	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.31
COAD	chr11	72231130	Missense_Mutation	NA	E480K	0.19	Exo_endo_phos
COAD	chr11	72237668	Missense_Mutation	rs374001069	R1142C	0.33
COAD	chr11	72229941	Missense_Mutation	novel	Q287H	0.32
COAD	chr11	72237711	Missense_Mutation	rs773081790	R1156Q	0.25
DLBC	chr11	72238113	Silent	rs776975989	I1208I	0.55
ESCA	chr11	72238750	3'UTR	novel		0.28
ESCA	chr11	72228745	Frame_Shift_Del	novel	*L141Pfs31**	0.16
ESCA	chr11	72237388	Frame_Shift_Ins	novel	*P1051Sfs34**	0.43
ESCA	chr11	72230135	Silent	novel	V318V	0.14
ESCA	chr11	72231130	Missense_Mutation	novel	E480Q	0.43	Exo_endo_phos
GBM	chr11	72232676	Missense_Mutation	novel	R588Q	0.11	Exo_endo_phos
GBM	chr11	72231562	Missense_Mutation	rs769074650	R521H	0.7	Exo_endo_phos
GBM	chr11	72231078	Frame_Shift_Ins	novel	*H464Pfs2**	0.07	Exo_endo_phos
GBM	chr11	72232744	Missense_Mutation	rs771815535	R611C	0.61	Exo_endo_phos
GBM	chr11	72231542	Frame_Shift_Del	novel	*K515Sfs16**	0.63	Exo_endo_phos
HNSC	chr11	72228772	Missense_Mutation	rs201045134	T148I	0.19
HNSC	chr11	72230123	Splice_Region	novel	V314V	0.14
HNSC	chr11	72235862	Missense_Mutation	novel	P919S	0.05
HNSC	chr11	72231135	Nonsense_Mutation	novel	W481*	0.39	Exo_endo_phos
HNSC	chr11	72231170	Missense_Mutation	novel	T493M	0.49	Exo_endo_phos
HNSC	chr11	72232675	Missense_Mutation	NA	R588W	0.14	Exo_endo_phos
HNSC	chr11	72228848	Splice_Site	NA	X173_splice	0.29
HNSC	chr11	72235698	Missense_Mutation	novel	E895K	0.36
KIRC	chr11	72233122	Missense_Mutation	novel	S667A	0.24	Exo_endo_phos
KIRC	chr11	72237404	Missense_Mutation	rs374103936	P1054A	0.24
KIRP	chr11	72237559	Silent	NA	P1105P	0.25
KIRP	chr11	72231184	Missense_Mutation	rs746333764	R498C	0.44	Exo_endo_phos
KIRP	chr11	72238564	3'UTR	novel		0.27
KIRP	chr11	72237332	Missense_Mutation	rs746017563	R1030W	0.17
KIRP	chr11	72230459	Silent	novel	V396V	0.45
KIRP	chr11	72233120	Missense_Mutation	rs748148293	G666V	0.42	Exo_endo_phos
LGG	chr11	72231573	Missense_Mutation	NA	V525I	0.32	Exo_endo_phos
LGG	chr11	72238106	Missense_Mutation	rs772149044	R1206Q	0.26
LGG	chr11	72228438	Missense_Mutation	novel	L113M	0.19
LGG	chr11	72231502	Missense_Mutation	novel	A501V	0.31	Exo_endo_phos
LGG	chr11	72232715	Missense_Mutation	novel	H601R	0.27	Exo_endo_phos
LIHC	chr11	72237716	Silent	NA	L1158L	0.44
LIHC	chr11	72237227	Nonsense_Mutation	NA	Q995*	0.26
LIHC	chr11	72233743	Splice_Region	NA	K737K	0.24
LIHC	chr11	72232693	Missense_Mutation	NA	D594Y	0.28	Exo_endo_phos
LIHC	chr11	72238355	3'UTR	novel		0.46
LUAD	chr11	72235412	Missense_Mutation	NA	V874M	0.17
LUAD	chr11	72238270	Missense_Mutation	novel	T1232A	0.31
LUAD	chr11	72233672	Missense_Mutation	rs750542712	V714I	0.15	Exo_endo_phos
LUAD	chr11	72237711	Missense_Mutation	NA	R1156L	0.34
LUAD	chr11	72235123	Missense_Mutation	novel	P808R	0.21
LUAD	chr11	72233701	Silent	NA	G723G	0.19
LUAD	chr11	72237731	Missense_Mutation	novel	G1163C	0.37
LUAD	chr11	72238362	3'UTR	novel		0.44
LUAD	chr11	72228208	Missense_Mutation	novel	H67Q	0.22
LUAD	chr11	72237264	Missense_Mutation	novel	A1007D	0.09
LUAD	chr11	72229205	Missense_Mutation	NA	A212S	0.15
LUAD	chr11	72231016	Missense_Mutation	NA	V442L	0.31	Exo_endo_phos
LUAD	chr11	72238101	Missense_Mutation	NA	W1204C	0.42
LUAD	chr11	72235175	Silent	rs371376566	V825V	0.36
LUAD	chr11	72238294	Missense_Mutation	NA	G1240W	0.19
LUSC	chr11	72231151	Missense_Mutation	novel	G487R	0.21	Exo_endo_phos
LUSC	chr11	72229488	Missense_Mutation	rs773871418	G228V	0.14
LUSC	chr11	72238125	Frame_Shift_Ins	novel	*Y1213Lfs2**	0.09
LUSC	chr11	72235721	Silent	novel	A902A	0.04
LUSC	chr11	72237608	Missense_Mutation	novel	S1122P	0.31
LUSC	chr11	72228435	Missense_Mutation	NA	A112P	0.22
LUSC	chr11	72228095	Intron	novel		0.21
LUSC	chr11	72237577	Silent	novel	G1111G	0.11
LUSC	chr11	72232911	Missense_Mutation	rs371380700	P630S	0.14	Exo_endo_phos
LUSC	chr11	72231149	Missense_Mutation	rs749091098	R486H	0.1	Exo_endo_phos
LUSC	chr11	72238276	Nonsense_Mutation	novel	E1234*	0.18
LUSC	chr11	72238277	Missense_Mutation	novel	E1234G	0.17
LUSC	chr11	72237181	Frame_Shift_Ins	novel	*S980Kfs4**	0.19
LUSC	chr11	72237183	Missense_Mutation	novel	S980I	0.2
LUSC	chr11	72228127	Intron	novel		0.11
LUSC	chr11	72235678	Frame_Shift_Del	novel	W888*	0.64
LUSC	chr11	72235931	Missense_Mutation	novel	G942W	0.19
LUSC	chr11	72235681	Frame_Shift_Del	novel	*I889Tfs69**	0.74
LUSC	chr11	72237162	Missense_Mutation	rs753171921	A973V	0.47
LUSC	chr11	72232724	Missense_Mutation	novel	W604L	0.09	Exo_endo_phos
LUSC	chr11	72238055	Missense_Mutation	novel	Q1189P	0.26
LUSC	chr11	72229485	Nonsense_Mutation	NA	S227*	0.16
LUSC	chr11	72232627	Missense_Mutation	novel	R572G	0.33	Exo_endo_phos
LUSC	chr11	72234301	Missense_Mutation	novel	Q745E	0.25
MESO	chr11	72235317	Missense_Mutation	rs749358400	K842R	0.21
MESO	chr11	72229196	Missense_Mutation	rs200692358	R209C	0.64
OV	chr11	72228193	Silent	NA	Y62Y	0.31
OV	chr11	72235689	Missense_Mutation	novel	D892N	0.14
OV	chr11	72234555	Silent	NA	A785A	0.25
OV	chr11	72235426	Silent	novel	R878R	0.16
OV	chr11	72228402	Silent	novel	L101L	0.08
OV	chr11	72230206	Missense_Mutation	rs774794017	R342Q	0.38
OV	chr11	72228353	Silent	rs531123246	S84S	0.39
OV	chr11	72228678	Splice_Site	novel	X133_splice	0.33
PAAD	chr11	72230829	Missense_Mutation	novel	M411V	0.19
PAAD	chr11	72237123	Splice_Site	novel	X960_splice	0.19
PRAD	chr11	72235445	Missense_Mutation	novel	L885F	0.14
PRAD	chr11	72237219	Frame_Shift_Del	novel	*V992Afs48**	0.04
PRAD	chr11	72228216	Missense_Mutation	novel	R70P	0.16
READ	chr11	72228155	Intron	novel		0.31
READ	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.53
READ	chr11	72235864	Silent	NA	P919P	0.68
SARC	chr11	72232306	Missense_Mutation	novel	H561L	0.86	Exo_endo_phos
SKCM	chr11	72235733	Silent	novel	S906S	0.3
SKCM	chr11	72237706	Silent	rs748865402	P1154P	0.21
SKCM	chr11	72235349	Silent	NA	L853L	0.57
SKCM	chr11	72237439	Frame_Shift_Ins	novel	*S1068Qfs17**	0.39
SKCM	chr11	72231061	Missense_Mutation	NA	E457K	0.27	Exo_endo_phos
SKCM	chr11	72233712	Missense_Mutation	NA	V727A	0.24
SKCM	chr11	72237500	Missense_Mutation	rs200480750	R1086C	0.29
SKCM	chr11	72230131	Missense_Mutation	NA	D317V	0.17
SKCM	chr11	72233090	Missense_Mutation	NA	S656F	0.52	Exo_endo_phos
SKCM	chr11	72229953	Silent	NA	S291S	0.13
SKCM	chr11	72231030	Silent	NA	F446F	0.2
SKCM	chr11	72233456	Missense_Mutation	novel	P686S	0.85	Exo_endo_phos
SKCM	chr11	72230460	Missense_Mutation	NA	S397G	0.2
SKCM	chr11	72235354	Silent	NA	T854T	0.35
SKCM	chr11	72234316	Missense_Mutation	NA	F750L	0.37
SKCM	chr11	72229746	Silent	novel	Q279Q	0.04
SKCM	chr11	72234599	Missense_Mutation	novel	S800L	0.11
SKCM	chr11	72237551	Missense_Mutation	novel	P1103S	0.33
SKCM	chr11	72228485	Silent	novel	D128D	0.3
SKCM	chr11	72228486	Missense_Mutation	rs745317721	R129W	0.3
SKCM	chr11	72228195	Frame_Shift_Del	novel	*K64Afs10**	0.15
SKCM	chr11	72235893	Missense_Mutation	novel	S929F	0.41
SKCM	chr11	72235894	Silent	novel	S929S	0.41
SKCM	chr11	72235938	Missense_Mutation	NA	P944L	0.14
SKCM	chr11	72231184	Missense_Mutation	rs746333764	R498C	0.33	Exo_endo_phos
SKCM	chr11	72235386	Missense_Mutation	NA	N865I	0.14
SKCM	chr11	72237436	Silent	NA	F1064F	0.26
SKCM	chr11	72237282	Missense_Mutation	NA	T1013I	0.3
SKCM	chr11	72235920	Missense_Mutation	rs144622174	P938L	0.34
SKCM	chr11	72228747	Missense_Mutation	NA	P140S	0.71
SKCM	chr11	72230810	Silent	NA	F404F	0.39
SKCM	chr11	72234351	Silent	NA	S761S	0.19
SKCM	chr11	72235181	Silent	NA	S827S	0.22
SKCM	chr11	72229556	Nonsense_Mutation	NA	Q251*	0.23
SKCM	chr11	72232964	Silent	novel	F647F	0.36
SKCM	chr11	72237166	Silent	rs200100388	A974A	0.26
SKCM	chr11	72230272	Splice_Site	NA	X364_splice	0.17
STAD	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.17
STAD	chr11	72237440	Frame_Shift_Del	NA	*S1068Afs63**	0.25
STAD	chr11	72228216	Missense_Mutation	NA	R70H	0.08
STAD	chr11	72237477	Missense_Mutation	rs750607140	R1078Q	0.31
STAD	chr11	72230998	Missense_Mutation	rs758142583	V436I	0.2	Exo_endo_phos
STAD	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.11
STAD	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.38
STAD	chr11	72231136	Silent	novel	L482L	0.33
STAD	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.69
STAD	chr11	72237283	Silent	NA	T1013T	0.32
STAD	chr11	72235712	Silent	novel	K899K	0.34
STAD	chr11	72231131	Missense_Mutation	NA	E480G	0.08	Exo_endo_phos
STAD	chr11	72231574	Missense_Mutation	NA	V525A	0.1	Exo_endo_phos
STAD	chr11	72235450	Splice_Region	rs778488522	Y886Y	0.24
STAD	chr11	72235720	Frame_Shift_Del	novel	*S904Lfs54**	0.11
STAD	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.6
STAD	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.34
STAD	chr11	72228132	Intron	novel		0.12
STAD	chr11	72235920	Missense_Mutation	rs144622174	P938L	0.27
STAD	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.07
STAD	chr11	72228370	Missense_Mutation	rs762663532	R90H	0.26
STAD	chr11	72228210	Missense_Mutation	NA	T68M	0.26
STAD	chr11	72228757	Missense_Mutation	rs781357595	P143L	0.19
STAD	chr11	72237675	Missense_Mutation	rs778488376	A1144V	0.64
STAD	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.3
STAD	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.25
STAD	chr11	72237166	Silent	rs200100388	A974A	0.26
STAD	chr11	72235189	Missense_Mutation	NA	G830D	0.1
STAD	chr11	72231191	Splice_Site	NA	X499_splice	0.07
STAD	chr11	72233088	In_Frame_Del	rs746559845	S656del	0.12	Exo_endo_phos
STAD	chr11	72232944	Missense_Mutation	NA	R641W	0.14	Exo_endo_phos
STAD	chr11	72237423	Missense_Mutation	NA	D1060V	0.16
STAD	chr11	72228216	Missense_Mutation	NA	R70H	0.42
THCA	chr11	72232722	Silent	NA	F603F	0.06
UCEC	chr11	72233721	Frame_Shift_Del	NA	*S731Pfs27**	0.89
UCEC	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.26
UCEC	chr11	72231009	Frame_Shift_Del	NA	*N441Tfs2**	0.42	Exo_endo_phos
UCEC	chr11	72238317	Missense_Mutation	novel	K1247N	0.42
UCEC	chr11	72228820	Missense_Mutation	NA	E164A	0.37
UCEC	chr11	72238350	Silent	novel	K1258K	0.19
UCEC	chr11	72238352	Frame_Shift_Ins	novel	*1259W	0.18
UCEC	chr11	72231148	Missense_Mutation	NA	R486C	0.36	Exo_endo_phos
UCEC	chr11	72237248	Frame_Shift_Del	NA	*S1003Rfs128**	0.37
UCEC	chr11	72228241	Missense_Mutation	NA	F78L	0.42
UCEC	chr11	72231111	Missense_Mutation	novel	E473D	0.1	Exo_endo_phos
UCEC	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.26
UCEC	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.53
UCEC	chr11	72238450	3'UTR	novel		0.21
UCEC	chr11	72231603	Missense_Mutation	novel	A535T	0.39	Exo_endo_phos
UCEC	chr11	72234347	Missense_Mutation	novel	A760D	0.37
UCEC	chr11	72228406	Missense_Mutation	novel	Y102C	0.25
UCEC	chr11	72234602	Missense_Mutation	novel	R801H	0.21
UCEC	chr11	72229725	Missense_Mutation	novel	K272N	0.39
UCEC	chr11	72235920	Missense_Mutation	rs144622174	P938L	0.5
UCEC	chr11	72238156	Missense_Mutation	novel	D1223N	0.21
UCEC	chr11	72238011	Splice_Site	novel	X1185_splice	0.2
UCEC	chr11	72231150	Silent	rs369385702	R486R	0.38
UCEC	chr11	72231537	Missense_Mutation	NA	L513M	0.3	Exo_endo_phos
UCEC	chr11	72237199	Silent	NA	A985A	0.21
UCEC	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.35
UCEC	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.48
UCEC	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.53
UCEC	chr11	72228353	Silent	rs531123246	S84S	0.27
UCEC	chr11	72231036	Silent	rs769618309	S448S	0.14
UCEC	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.78
UCEC	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.57
UCEC	chr11	72238315	Nonsense_Mutation	novel	K1247*	0.5
UCEC	chr11	72237520	Missense_Mutation	novel	K1092N	0.16
UCEC	chr11	72228373	Missense_Mutation	rs142516692	R91H	0.52
UCEC	chr11	72237331	Silent	NA	H1029H	0.4
UCEC	chr11	72231015	Frame_Shift_Del	novel	*N441Kfs2**	0.43	Exo_endo_phos
UCEC	chr11	72230361	Splice_Site	NA	X364_splice	0.35
UCEC	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.23
UCEC	chr11	72228216	Missense_Mutation	NA	R70H	0.2
UCEC	chr11	72238789	3'UTR	rs371837004		0.36
UCEC	chr11	72229698	Silent	novel	S263S	0.41
UCEC	chr11	72229686	Missense_Mutation	novel	Q259H	0.2
UCEC	chr11	72238942	3'UTR	novel		0.31
UCEC	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.34
UCEC	chr11	72233142	Nonsense_Mutation	NA	W673*	0.62	Exo_endo_phos
UCEC	chr11	72228400	Missense_Mutation	novel	G100D	0.19
UCEC	chr11	72234594	Nonsense_Mutation	novel	W798*	0.17
UCEC	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.39
UCEC	chr11	72229560	Splice_Site	novel	X251_splice	0.3
UCEC	chr11	72232907	Silent	rs775640484	F628F	0.47
UCEC	chr11	72238072	Frame_Shift_Ins	novel	*E1198Gfs7**	0.27
UCEC	chr11	72228370	Missense_Mutation	rs762663532	R90H	0.36
UCEC	chr11	72235735	Missense_Mutation	NA	R907Q	0.32
UCEC	chr11	72232335	Missense_Mutation	NA	R571W	0.17	Exo_endo_phos
UCEC	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.42
UCEC	chr11	72228349	Missense_Mutation	novel	T83I	0.65
UCEC	chr11	72230806	Missense_Mutation	novel	A403V	0.47
UCEC	chr11	72229681	Missense_Mutation	novel	E258K	0.48
UCEC	chr11	72231562	Missense_Mutation	rs769074650	R521H	0.36	Exo_endo_phos
UCEC	chr11	72235199	Silent	novel	S833S	0.53
UCEC	chr11	72235921	Silent	rs372904912	P938P	0.49
UCEC	chr11	72239069	3'UTR	novel		0.58
UCEC	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.37
UCEC	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.89
UCEC	chr11	72233744	Missense_Mutation	NA	G738R	0.33
UCEC	chr11	72232744	Missense_Mutation	rs771815535	R611C	0.44	Exo_endo_phos
UCEC	chr11	72232336	Missense_Mutation	NA	R571Q	0.1	Exo_endo_phos
UCEC	chr11	72231111	Missense_Mutation	novel	E473D	0.36	Exo_endo_phos
UCEC	chr11	72228068	Intron	novel		0.48
UCEC	chr11	72229119	Missense_Mutation	novel	H183R	0.34
UCEC	chr11	72230184	Missense_Mutation	novel	S335G	0.35
UCEC	chr11	72237439	Frame_Shift_Ins	novel	*S1068Qfs17**	0.38
UCEC	chr11	72231009	Frame_Shift_Del	NA	*N441Tfs2**	0.31	Exo_endo_phos
UCEC	chr11	72230867	Missense_Mutation	novel	M423I	0.24
UCEC	chr11	72237308	Missense_Mutation	novel	P1022S	0.33
UCEC	chr11	72237455	Missense_Mutation	novel	P1071S	0.39
UCEC	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.43
UCEC	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.52
UCEC	chr11	72229212	Nonsense_Mutation	NA	S214*	0.44
UCEC	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.39
UCEC	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.32
UCEC	chr11	72238319	Missense_Mutation	novel	R1248H	0.36
UCEC	chr11	72233517	Missense_Mutation	novel	S706Y	0.38	Exo_endo_phos
UCEC	chr11	72235424	Missense_Mutation	NA	R878C	0.5
UCEC	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.96
UCEC	chr11	72234601	Missense_Mutation	rs144781166	R801C	0.3
UCEC	chr11	72232246	Frame_Shift_Ins	novel	*A543Gfs9**	0.41	Exo_endo_phos
UCEC	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.55
UCEC	chr11	72228736	Missense_Mutation	novel	D136G	0.26
UCEC	chr11	72230269	Missense_Mutation	novel	R363H	0.29
UCEC	chr11	72235843	Splice_Region	novel		0.25
UCEC	chr11	72237548	Missense_Mutation	novel	G1102C	0.32
UCEC	chr11	72238984	3'UTR	novel		0.36
UCEC	chr11	72234615	Splice_Region	novel	T805T	0.28
UCEC	chr11	72237549	Frame_Shift_Ins	novel	*S1104Lfs15**	0.37
UCEC	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.33
UCEC	chr11	72229206	Missense_Mutation	rs550597792	A212V	0.26
UCEC	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.38
UCEC	chr11	72237223	Silent	rs140390051	P993P	0.56
UCEC	chr11	72238066	Missense_Mutation	NA	A1193T	0.32
UCEC	chr11	72232973	Splice_Region	rs780987682	F650F	0.4
UCEC	chr11	72231009	Frame_Shift_Del	NA	*N441Tfs2**	0.3	Exo_endo_phos
UCEC	chr11	72237440	Frame_Shift_Del	NA	*S1068Afs63**	0.22
UCEC	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.8
UCEC	chr11	72235450	Splice_Region	rs778488522	Y886Y	0.14
UCEC	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.48
UCEC	chr11	72232335	Missense_Mutation	NA	R571W	0.45	Exo_endo_phos
UCEC	chr11	72233471	Missense_Mutation	NA	R691W	0.48	Exo_endo_phos
UCEC	chr11	72233472	Missense_Mutation	NA	R691Q	0.57	Exo_endo_phos
UCEC	chr11	72238157	Missense_Mutation	NA	D1223G	0.71
UCEC	chr11	72228845	Missense_Mutation	novel	E172D	0.43
UCEC	chr11	72228407	Silent	rs779291537	Y102Y	0.12
UCEC	chr11	72231035	Missense_Mutation	rs139442327	S448L	0.45	Exo_endo_phos
UCEC	chr11	72231603	Missense_Mutation	novel	A535T	0.22	Exo_endo_phos
UCEC	chr11	72235373	Missense_Mutation	novel	E861K	0.39
UCEC	chr11	72228248	Frame_Shift_Del	novel	*V81Cfs37**	0.45
UCEC	chr11	72230147	Silent	novel	D322D	0.43
UCEC	chr11	72232309	Missense_Mutation	novel	L562H	0.4	Exo_endo_phos
UCEC	chr11	72237420	Missense_Mutation	rs769801718	P1059L	0.37
UCEC	chr11	72232695	Silent	NA	D594D	0.22
UCEC	chr11	72237165	Frame_Shift_Del	NA	*P976Hfs155**	0.39
UCEC	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.9
UCEC	chr11	72229539	Missense_Mutation	NA	T245N	0.36
UCEC	chr11	72233688	Frame_Shift_Del	novel	*V721Cfs37**	0.38
UCEC	chr11	72235384	Silent	novel	G864G	0.29
UCEC	chr11	72230230	Missense_Mutation	rs754842505	R350Q	0.33
UCEC	chr11	72234369	Silent	rs753024181	I767I	0.39
UCEC	chr11	72238120	Missense_Mutation	rs145567466	E1211K	0.34
UCEC	chr11	72238678	3'UTR	novel		0.41
UCEC	chr11	72238820	3'UTR	novel		0.45
UCS	chr11	72237704	Frame_Shift_Del	rs764259451	*R1156Gfs46**	0.38
UCS	chr11	72237711	Frame_Shift_Del	novel	*G1157Dfs45**	0.44

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ESCA	AMP	0.3315	0.018342
TGCT	DEL	0.7267	0.21504

Survival Analysis

Cancer	P-value	Q-value
THYM	0.03	Kaplan-Meier Survival Analysis
KIRC	0.0041	Kaplan-Meier Survival Analysis
SARC	0.042	Kaplan-Meier Survival Analysis
MESO	0.011	Kaplan-Meier Survival Analysis
ACC	0.00025	Kaplan-Meier Survival Analysis
UCS	0.019	Kaplan-Meier Survival Analysis
SKCM	0.05	Kaplan-Meier Survival Analysis
LUSC	0.031	Kaplan-Meier Survival Analysis
CESC	0.042	Kaplan-Meier Survival Analysis
LAML	0.014	Kaplan-Meier Survival Analysis
GBM	0.034	Kaplan-Meier Survival Analysis
LIHC	0.0021	Kaplan-Meier Survival Analysis
LGG	0.00011	Kaplan-Meier Survival Analysis
THCA	0.0052	Kaplan-Meier Survival Analysis
LUAD	0.022	Kaplan-Meier Survival Analysis
UVM	0.00025	Kaplan-Meier Survival Analysis
OV	0.024	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000165458 (Gene tree)
Gene ID: 3636
Gene Symbol: INPPL1
Alias: SHIP2
Full Name: inositol polyphosphate phosphatase like 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 15,447 bases
Position: chr11:72,223,701-72,239,147
Accession: 6080
RBP type: canonical RBP
Summary: The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer. [provided by RefSeq, Jan 2009]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000444619	Exo_endo_phos	PF03372.23	3.2e-12	1	1
ENSP00000446360	Exo_endo_phos	PF03372.23	4e-12	1	1
ENSP00000298229	Exo_endo_phos	PF03372.23	4.8e-12	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
17123777	Transcriptional profiling of C2C12 myotubes in response to SHIP2 depletion and insulin stimulation.	Genomics	2007 Feb	Huard C	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000538339	INPPL1-206	505	-	-	- (aa)	-	-
ENST00000541752	INPPL1-212	856	-	ENSP00000441094	197 (aa)	-	H0YFZ4
ENST00000537755	INPPL1-205	535	-	-	- (aa)	-	-
ENST00000541544	INPPL1-211	530	-	-	- (aa)	-	-
ENST00000544806	INPPL1-215	547	-	-	- (aa)	-	-
ENST00000541303	INPPL1-210	1238	-	-	- (aa)	-	-
ENST00000537656	INPPL1-204	550	-	ENSP00000444630	33 (aa)	-	F5H588
ENST00000545355	INPPL1-216	1124	-	-	- (aa)	-	-
ENST00000543234	INPPL1-214	275	-	ENSP00000440512	17 (aa)	-	F5GWY9
ENST00000540973	INPPL1-209	375	-	ENSP00000440904	22 (aa)	-	F5GYK9
ENST00000540329	INPPL1-208	741	-	ENSP00000440018	127 (aa)	-	F5GY16
ENST00000538751	INPPL1-207	4656	-	ENSP00000444619	1016 (aa)	-	O15357
ENST00000535985	INPPL1-203	353	-	ENSP00000437852	41 (aa)	-	H0YFB4
ENST00000320683	INPPL1-202	717	-	ENSP00000321775	149 (aa)	-	H7BXR2
ENST00000298229	INPPL1-201	4733	XM_005273979	ENSP00000298229	1258 (aa)	XP_005274036	O15357
ENST00000541756	INPPL1-213	4649	-	ENSP00000446360	1146 (aa)	-	A0A0A0MTP6

Gene Model

Click here to download ENSG00000165458's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa00562	Inositol phosphate metabolism	KEGG
hsa01100	Metabolic pathways	KEGG
hsa04070	Phosphatidylinositol signaling system	KEGG
hsa04662	B cell receptor signaling pathway	KEGG
hsa04666	Fc gamma R-mediated phagocytosis	KEGG
hsa04910	Insulin signaling pathway	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000165458's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000165458	INPPL1	99	73.469	ENSAPOG00000002267	inppl1a	98	77.217	Acanthochromis_polyacanthus
ENSG00000165458	INPPL1	100	97.837	ENSAMEG00000005610	INPPL1	99	96.730	Ailuropoda_melanoleuca
ENSG00000165458	INPPL1	96	70.732	ENSACIG00000008932	inppl1a	87	76.085	Amphilophus_citrinellus
ENSG00000165458	INPPL1	95	74.590	ENSAOCG00000016059	inppl1a	96	78.596	Amphiprion_ocellaris
ENSG00000165458	INPPL1	100	73.438	ENSAPEG00000017439	inppl1a	96	78.251	Amphiprion_percula
ENSG00000165458	INPPL1	93	81.437	ENSATEG00000006407	inppl1a	97	79.306	Anabas_testudineus
ENSG00000165458	INPPL1	96	81.301	ENSACAG00000015570	INPPL1	100	72.535	Anolis_carolinensis
ENSG00000165458	INPPL1	100	100.000	ENSANAG00000027766	INPPL1	100	97.695	Aotus_nancymaae
ENSG00000165458	INPPL1	96	72.581	ENSACLG00000007842	inppl1a	98	67.557	Astatotilapia_calliptera
ENSG00000165458	INPPL1	93	62.538	ENSAMXG00000011596	inppl1a	77	83.761	Astyanax_mexicanus
ENSG00000165458	INPPL1	100	97.247	ENSBTAG00000019167	INPPL1	100	96.598	Bos_taurus
ENSG00000165458	INPPL1	100	100.000	ENSCJAG00000015191	INPPL1	100	97.783	Callithrix_jacchus
ENSG00000165458	INPPL1	100	97.148	ENSCAFG00000005743	INPPL1	100	96.361	Canis_familiaris
ENSG00000165458	INPPL1	100	96.657	ENSCAFG00020003281	INPPL1	100	95.965	Canis_lupus_dingo
ENSG00000165458	INPPL1	100	97.247	ENSCHIG00000015058	INPPL1	100	96.598	Capra_hircus
ENSG00000165458	INPPL1	100	100.000	ENSTSYG00000004075	INPPL1	95	97.412	Carlito_syrichta
ENSG00000165458	INPPL1	100	93.939	ENSCAPG00000016058	INPPL1	97	92.869	Cavia_aperea
ENSG00000165458	INPPL1	100	96.275	ENSCPOG00000014786	INPPL1	98	96.151	Cavia_porcellus
ENSG00000165458	INPPL1	100	98.228	ENSCCAG00000024212	INPPL1	100	97.704	Cebus_capucinus
ENSG00000165458	INPPL1	100	100.000	ENSCATG00000038751	INPPL1	100	98.569	Cercocebus_atys
ENSG00000165458	INPPL1	100	100.000	ENSCLAG00000014240	INPPL1	100	96.349	Chinchilla_lanigera
ENSG00000165458	INPPL1	100	100.000	ENSCSAG00000004156	INPPL1	100	98.490	Chlorocebus_sabaeus
ENSG00000165458	INPPL1	96	82.927	ENSCPBG00000004673	INPPL1	97	78.644	Chrysemys_picta_bellii
ENSG00000165458	INPPL1	98	49.505	ENSCPBG00000014360	-	90	55.276	Chrysemys_picta_bellii
ENSG00000165458	INPPL1	100	100.000	ENSCANG00000027708	INPPL1	100	97.774	Colobus_angolensis_palliatus
ENSG00000165458	INPPL1	100	96.970	ENSCGRG00001008145	Inppl1	100	95.473	Cricetulus_griseus_chok1gshd
ENSG00000165458	INPPL1	100	96.970	ENSCGRG00000001437	Inppl1	100	93.380	Cricetulus_griseus_crigri
ENSG00000165458	INPPL1	96	74.797	ENSCSEG00000018990	inppl1a	98	67.136	Cynoglossus_semilaevis
ENSG00000165458	INPPL1	96	74.797	ENSCVAG00000017600	inppl1a	98	65.578	Cyprinodon_variegatus
ENSG00000165458	INPPL1	94	74.167	ENSDARG00000104222	inppl1a	70	75.905	Danio_rerio
ENSG00000165458	INPPL1	100	93.939	ENSDNOG00000009804	INPPL1	100	97.101	Dasypus_novemcinctus
ENSG00000165458	INPPL1	100	95.280	ENSDORG00000011283	Inppl1	100	95.971	Dipodomys_ordii
ENSG00000165458	INPPL1	100	94.416	ENSETEG00000017131	INPPL1	90	96.158	Echinops_telfairi
ENSG00000165458	INPPL1	68	55.956	ENSEBUG00000004336	inppl1a	83	45.949	Eptatretus_burgeri
ENSG00000165458	INPPL1	93	55.023	ENSEBUG00000016421	inppl1a	91	54.882	Eptatretus_burgeri
ENSG00000165458	INPPL1	100	97.542	ENSEASG00005000512	INPPL1	100	96.756	Equus_asinus_asinus
ENSG00000165458	INPPL1	100	97.542	ENSECAG00000017064	INPPL1	100	96.756	Equus_caballus
ENSG00000165458	INPPL1	100	84.848	ENSEEUG00000002888	INPPL1	98	88.646	Erinaceus_europaeus
ENSG00000165458	INPPL1	96	72.951	ENSELUG00000011031	inppl1a	93	88.372	Esox_lucius
ENSG00000165458	INPPL1	100	97.935	ENSFCAG00000005323	INPPL1	100	97.231	Felis_catus
ENSG00000165458	INPPL1	100	75.758	ENSFALG00000006266	INPPL1	100	73.099	Ficedula_albicollis
ENSG00000165458	INPPL1	96	40.000	ENSFALG00000004153	-	99	56.498	Ficedula_albicollis
ENSG00000165458	INPPL1	100	96.970	ENSFDAG00000015879	INPPL1	98	95.587	Fukomys_damarensis
ENSG00000165458	INPPL1	100	73.438	ENSFHEG00000003021	inppl1a	97	67.591	Fundulus_heteroclitus
ENSG00000165458	INPPL1	96	73.171	ENSGMOG00000017399	inppl1a	85	77.480	Gadus_morhua
ENSG00000165458	INPPL1	96	36.800	ENSGALG00000004336	INPPL1	86	52.772	Gallus_gallus
ENSG00000165458	INPPL1	91	82.946	ENSGAFG00000008310	inppl1a	95	80.437	Gambusia_affinis
ENSG00000165458	INPPL1	96	72.131	ENSGACG00000007795	inppl1a	98	67.379	Gasterosteus_aculeatus
ENSG00000165458	INPPL1	55	71.779	ENSGAGG00000013511	-	87	68.381	Gopherus_agassizii
ENSG00000165458	INPPL1	96	84.553	ENSGAGG00000000760	INPPL1	99	75.136	Gopherus_agassizii
ENSG00000165458	INPPL1	100	100.000	ENSGGOG00000011295	INPPL1	99	99.332	Gorilla_gorilla
ENSG00000165458	INPPL1	96	72.581	ENSHBUG00000015510	inppl1a	98	67.478	Haplochromis_burtoni
ENSG00000165458	INPPL1	100	96.970	ENSHGLG00000009057	INPPL1	100	96.047	Heterocephalus_glaber_female
ENSG00000165458	INPPL1	100	96.970	ENSHGLG00100002541	INPPL1	99	93.307	Heterocephalus_glaber_male
ENSG00000165458	INPPL1	96	73.984	ENSHCOG00000014440	inppl1a	96	79.777	Hippocampus_comes
ENSG00000165458	INPPL1	96	68.033	ENSIPUG00000014726	inppl1a	99	77.536	Ictalurus_punctatus
ENSG00000165458	INPPL1	100	95.870	ENSSTOG00000010874	INPPL1	100	95.631	Ictidomys_tridecemlineatus
ENSG00000165458	INPPL1	100	96.970	ENSJJAG00000013756	Inppl1	100	95.714	Jaculus_jaculus
ENSG00000165458	INPPL1	96	72.358	ENSKMAG00000001455	inppl1a	98	66.823	Kryptolebias_marmoratus
ENSG00000165458	INPPL1	96	73.171	ENSLBEG00000027829	inppl1a	95	80.473	Labrus_bergylta
ENSG00000165458	INPPL1	96	42.857	ENSLACG00000013370	-	99	59.757	Latimeria_chalumnae
ENSG00000165458	INPPL1	99	65.666	ENSLOCG00000007744	inppl1a	80	70.504	Lepisosteus_oculatus
ENSG00000165458	INPPL1	100	96.970	ENSLAFG00000000930	INPPL1	100	96.047	Loxodonta_africana
ENSG00000165458	INPPL1	100	100.000	ENSMFAG00000037937	INPPL1	100	98.622	Macaca_fascicularis
ENSG00000165458	INPPL1	100	100.000	ENSMMUG00000010451	INPPL1	100	98.524	Macaca_mulatta
ENSG00000165458	INPPL1	100	100.000	ENSMNEG00000031772	INPPL1	100	98.490	Macaca_nemestrina
ENSG00000165458	INPPL1	100	100.000	ENSMLEG00000007523	INPPL1	100	98.003	Mandrillus_leucophaeus
ENSG00000165458	INPPL1	96	75.610	ENSMAMG00000006179	inppl1a	98	66.129	Mastacembelus_armatus
ENSG00000165458	INPPL1	96	72.581	ENSMZEG00005007511	inppl1a	98	67.557	Maylandia_zebra
ENSG00000165458	INPPL1	70	56.604	ENSMGAG00000001328	INPPL1	99	56.604	Meleagris_gallopavo
ENSG00000165458	INPPL1	100	96.970	ENSMAUG00000001936	Inppl1	100	95.711	Mesocricetus_auratus
ENSG00000165458	INPPL1	100	100.000	ENSMICG00000011696	INPPL1	98	97.245	Microcebus_murinus
ENSG00000165458	INPPL1	100	96.970	ENSMOCG00000008314	Inppl1	100	95.631	Microtus_ochrogaster
ENSG00000165458	INPPL1	96	74.797	ENSMMOG00000010408	inppl1a	82	71.754	Mola_mola
ENSG00000165458	INPPL1	100	90.909	ENSMODG00000008002	INPPL1	99	86.378	Monodelphis_domestica
ENSG00000165458	INPPL1	93	64.367	ENSMALG00000002411	inppl1a	93	66.667	Monopterus_albus
ENSG00000165458	INPPL1	100	96.970	MGP_CAROLIEiJ_G0030066	Inppl1	100	95.711	Mus_caroli
ENSG00000165458	INPPL1	100	96.970	ENSMUSG00000032737	Inppl1	100	95.790	Mus_musculus
ENSG00000165458	INPPL1	100	96.970	MGP_PahariEiJ_G0013287	Inppl1	100	95.711	Mus_pahari
ENSG00000165458	INPPL1	100	95.969	MGP_SPRETEiJ_G0031177	Inppl1	100	95.711	Mus_spretus
ENSG00000165458	INPPL1	100	97.837	ENSMPUG00000010200	INPPL1	100	96.598	Mustela_putorius_furo
ENSG00000165458	INPPL1	100	96.970	ENSMLUG00000014132	INPPL1	99	96.102	Myotis_lucifugus
ENSG00000165458	INPPL1	100	96.970	ENSNGAG00000005410	Inppl1	100	96.426	Nannospalax_galili
ENSG00000165458	INPPL1	96	72.581	ENSNBRG00000004581	inppl1a	98	63.328	Neolamprologus_brichardi
ENSG00000165458	INPPL1	100	100.000	ENSNLEG00000017207	INPPL1	100	99.081	Nomascus_leucogenys
ENSG00000165458	INPPL1	100	93.939	ENSOPRG00000002750	INPPL1	78	100.000	Ochotona_princeps
ENSG00000165458	INPPL1	100	94.912	ENSODEG00000006960	INPPL1	99	95.196	Octodon_degus
ENSG00000165458	INPPL1	96	72.581	ENSONIG00000016738	inppl1a	98	68.396	Oreochromis_niloticus
ENSG00000165458	INPPL1	100	97.738	ENSOCUG00000000167	INPPL1	100	97.245	Oryctolagus_cuniculus
ENSG00000165458	INPPL1	96	72.358	ENSORLG00000011228	inppl1a	98	67.190	Oryzias_latipes
ENSG00000165458	INPPL1	96	72.358	ENSORLG00020000412	inppl1a	98	67.111	Oryzias_latipes_hni
ENSG00000165458	INPPL1	96	72.358	ENSORLG00015000617	inppl1a	98	66.954	Oryzias_latipes_hsok
ENSG00000165458	INPPL1	96	73.171	ENSOMEG00000002830	inppl1a	98	66.903	Oryzias_melastigma
ENSG00000165458	INPPL1	100	96.970	ENSOGAG00000012996	INPPL1	99	95.886	Otolemur_garnettii
ENSG00000165458	INPPL1	100	96.970	ENSOARG00000004577	INPPL1	99	96.493	Ovis_aries
ENSG00000165458	INPPL1	100	100.000	ENSPPAG00000044079	INPPL1	99	97.134	Pan_paniscus
ENSG00000165458	INPPL1	100	97.640	ENSPPRG00000003083	INPPL1	100	96.915	Panthera_pardus
ENSG00000165458	INPPL1	100	97.148	ENSPTIG00000014051	INPPL1	97	96.849	Panthera_tigris_altaica
ENSG00000165458	INPPL1	100	100.000	ENSPTRG00000004031	INPPL1	100	99.606	Pan_troglodytes
ENSG00000165458	INPPL1	100	100.000	ENSPANG00000002495	INPPL1	100	98.569	Papio_anubis
ENSG00000165458	INPPL1	96	70.732	ENSPKIG00000022920	inppl1a	75	74.033	Paramormyrops_kingsleyae
ENSG00000165458	INPPL1	79	55.104	ENSPSIG00000011053	-	86	55.005	Pelodiscus_sinensis
ENSG00000165458	INPPL1	96	82.927	ENSPSIG00000002289	INPPL1	97	73.072	Pelodiscus_sinensis
ENSG00000165458	INPPL1	96	74.797	ENSPMGG00000021906	inppl1a	80	72.200	Periophthalmus_magnuspinnatus
ENSG00000165458	INPPL1	100	96.970	ENSPEMG00000001871	Inppl1	100	95.552	Peromyscus_maniculatus_bairdii
ENSG00000165458	INPPL1	100	89.453	ENSPCIG00000021609	INPPL1	98	90.873	Phascolarctos_cinereus
ENSG00000165458	INPPL1	96	73.171	ENSPFOG00000008661	inppl1a	98	67.557	Poecilia_formosa
ENSG00000165458	INPPL1	96	73.171	ENSPLAG00000018457	inppl1a	98	67.478	Poecilia_latipinna
ENSG00000165458	INPPL1	96	73.171	ENSPMEG00000021651	inppl1a	98	67.610	Poecilia_mexicana
ENSG00000165458	INPPL1	96	73.171	ENSPREG00000019344	inppl1a	98	67.191	Poecilia_reticulata
ENSG00000165458	INPPL1	100	100.000	ENSPPYG00000003649	INPPL1	100	98.172	Pongo_abelii
ENSG00000165458	INPPL1	100	96.970	ENSPCAG00000006719	INPPL1	80	96.748	Procavia_capensis
ENSG00000165458	INPPL1	100	100.000	ENSPCOG00000017270	INPPL1	100	96.902	Propithecus_coquereli
ENSG00000165458	INPPL1	100	96.970	ENSPVAG00000002483	INPPL1	100	94.146	Pteropus_vampyrus
ENSG00000165458	INPPL1	96	72.581	ENSPNYG00000013271	inppl1a	98	67.557	Pundamilia_nyererei
ENSG00000165458	INPPL1	93	75.424	ENSPNAG00000000674	inppl1a	71	69.169	Pygocentrus_nattereri
ENSG00000165458	INPPL1	100	96.970	ENSRNOG00000019730	Inppl1	100	96.859	Rattus_norvegicus
ENSG00000165458	INPPL1	100	100.000	ENSRBIG00000040337	INPPL1	100	97.933	Rhinopithecus_bieti
ENSG00000165458	INPPL1	100	100.000	ENSRROG00000030610	INPPL1	100	98.092	Rhinopithecus_roxellana
ENSG00000165458	INPPL1	100	98.130	ENSSBOG00000028042	INPPL1	100	98.130	Saimiri_boliviensis_boliviensis
ENSG00000165458	INPPL1	100	87.879	ENSSHAG00000006877	INPPL1	100	89.167	Sarcophilus_harrisii
ENSG00000165458	INPPL1	100	64.700	ENSSFOG00015016243	inppl1a	99	63.984	Scleropages_formosus
ENSG00000165458	INPPL1	96	73.171	ENSSMAG00000019580	inppl1a	98	66.563	Scophthalmus_maximus
ENSG00000165458	INPPL1	96	73.984	ENSSDUG00000000456	inppl1a	97	76.648	Seriola_dumerili
ENSG00000165458	INPPL1	96	73.984	ENSSLDG00000020696	inppl1a	97	79.665	Seriola_lalandi_dorsalis
ENSG00000165458	INPPL1	98	48.400	ENSSPUG00000001849	-	91	53.507	Sphenodon_punctatus
ENSG00000165458	INPPL1	100	81.818	ENSSPUG00000006321	INPPL1	81	79.301	Sphenodon_punctatus
ENSG00000165458	INPPL1	96	73.171	ENSSPAG00000020205	inppl1a	98	67.656	Stegastes_partitus
ENSG00000165458	INPPL1	100	96.970	ENSSSCG00000014811	INPPL1	100	94.933	Sus_scrofa
ENSG00000165458	INPPL1	96	35.659	ENSTGUG00000002648	-	98	60.092	Taeniopygia_guttata
ENSG00000165458	INPPL1	99	65.433	ENSTRUG00000009438	inppl1a	98	65.588	Takifugu_rubripes
ENSG00000165458	INPPL1	57	92.690	ENSTBEG00000012162	INPPL1	70	92.690	Tupaia_belangeri
ENSG00000165458	INPPL1	100	97.935	ENSUAMG00000027397	INPPL1	99	96.820	Ursus_americanus
ENSG00000165458	INPPL1	100	96.970	ENSUMAG00000007967	INPPL1	99	94.698	Ursus_maritimus
ENSG00000165458	INPPL1	100	97.345	ENSVVUG00000024927	INPPL1	100	97.345	Vulpes_vulpes
ENSG00000165458	INPPL1	96	73.171	ENSXMAG00000011097	inppl1a	98	67.402	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001958	endochondral ossification	23273569.	IMP	Process
GO:0002376	immune system process	-	IEA	Process
GO:0003779	actin binding	-	IEA	Function
GO:0005515	protein binding	11158326.12504111.16302969.18692052.20368287.20933011.21712384.24728074.	IPI	Function
GO:0005794	Golgi apparatus	-	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005856	cytoskeleton	-	IEA	Component
GO:0005886	plasma membrane	-	IEA	Component
GO:0006006	glucose metabolic process	-	IEA	Process
GO:0006661	phosphatidylinositol biosynthetic process	-	TAS	Process
GO:0006897	endocytosis	15668240.	IMP	Process
GO:0007015	actin filament organization	15668240.	IMP	Process
GO:0007155	cell adhesion	15668240.	TAS	Process
GO:0008285	negative regulation of cell proliferation	-	IEA	Process
GO:0009791	post-embryonic development	-	IEA	Process
GO:0010629	negative regulation of gene expression	-	IEA	Process
GO:0016787	hydrolase activity	-	IEA	Function
GO:0017124	SH3 domain binding	-	IEA	Function
GO:0019221	cytokine-mediated signaling pathway	-	TAS	Process
GO:0030027	lamellipodium	-	IEA	Component
GO:0030175	filopodium	-	IEA	Component
GO:0032868	response to insulin	-	IEA	Process
GO:0042169	SH2 domain binding	5668240.	IPI	Function
GO:0043647	inositol phosphate metabolic process	-	TAS	Process
GO:0046856	phosphatidylinositol dephosphorylation	-	IEA	Process
GO:0097178	ruffle assembly	-	IEA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.