EuRBPDB

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TCGA tumor abbreviations
  • ACCAdrenocortical carcinoma
  • BLCABladder Urothelial Carcinoma
  • BRCABreast invasive carcinoma
  • CESCCervical squamous cell carcinoma and endocervical adenocarcinoma
  • CHOLCholangio carcinoma
  • COADColon adenocarcinoma
  • DLBCLymphoid Neoplasm Diffuse Large B-cell Lymphoma
  • ESCAEsophageal carcinoma
  • GBMGlioblastoma multiforme
  • HNSCHead and Neck squamous cell carcinoma
  • KICHKidney Chromophobe
  • KIRCKidney renal clear cell carcinoma
  • KIRPKidney renal papillary cell carcinoma
  • LAMLAcute Myeloid Leukemia
  • LGGBrain Lower Grade Glioma
  • LIHCLiver hepatocellular carcinoma
  • LUADLung adenocarcinoma
  • LUSCLung squamous cell carcinoma
  • MESOMesothelioma
  • OVOvarian serous cystadenocarcinoma
  • PAADPancreatic adenocarcinoma
  • PCPGPheochromocytoma and Paraganglioma
  • PRADProstate adenocarcinoma
  • READRectum adenocarcinoma
  • SARCSarcoma
  • SKCMSkin Cutaneous Melanoma
  • STADStomach adenocarcinoma
  • TGCTThyroid carcinoma
  • THCAThyroid carcinoma
  • THYMThymoma
  • UCECUterine Corpus Endometrial Carcinoma
  • UCSUterine Carcinosarcoma
  • UVMUveal Melanoma

Note: Click here to get the extension of tumor abbreviations.


  • Cancer Related Information
  • Basic Information

Cancer associated literatures
PIDTitleArticle TimeAuthorDoi
18607064Molecular detection of neuron-specific ELAV-like-positive cells in the peripheral blood of patients with small-cell lung cancer.Cell Oncol2008D'Alessandro V-

Differential Expression

Expression in 33 cancers

Mutations
CancerChrPosition Mutation TypedbSNPProtein-change Allele FreqRBD
ACCchr150193912Missense_MutationnovelV168F0.41
ACCchr1502011833'UTRnovel0.95
ACCchr150145145Silentrs754162796F66F0.4
ACCchr150193816Missense_MutationnovelV136F0.25
BLCAchr150200925Missense_MutationnovelW297S0.22
BLCAchr150200986SilentNAF317F0.2
BLCAchr150145094SilentNAI49I0.18
BLCAchr150200835Missense_MutationNAS267F0.22
BLCAchr150201132Missense_MutationnovelR366T0.65RRM_5
BLCAchr150177098Nonsense_MutationNAL87*0.13
BLCAchr150200927Missense_MutationnovelC298R0.05
BLCAchr1501091565'UTRnovel0.1
BLCAchr150145140Missense_MutationNAL65F0.14
BLCAchr1501039695'Flanknovel0.13
BLCAchr150195593Missense_MutationnovelD181H0.31
BLCAchr150177146Missense_MutationNAA103V0.29
BLCAchr150197432Frame_Shift_InsnovelL250Tfs*100.19
BLCAchr150195611Missense_MutationNAE187K0.28
BRCAchr1501063875'FlankNA0.29
BRCAchr1502014733'Flanknovel0.63
BRCAchr150195598Missense_MutationNAK182N0.1
BRCAchr150109843Intronnovel0.19
BRCAchr150145145Silentrs754162796F66F0.1
BRCAchr150201055Silentrs764075721F340F0.33
CESCchr150195588Missense_MutationNAR179H0.22
CESCchr150195588Missense_MutationNAR179H0.1
CESCchr150195778Missense_MutationnovelQ242H0.24
CESCchr150193868Missense_MutationNAS153L0.26
CESCchr150193829Missense_MutationnovelP140L0.35
CESCchr1501091365'UTRnovel0.23
CHOLchr1502012393'UTRnovel0.06
COADchr150195575Missense_MutationnovelV175M0.21
COADchr150200934Missense_MutationNAF300S0.37
COADchr150197459Silentrs761380670G255G0.31
COADchr1502012243'UTRnovel0.42
COADchr150201023Missense_MutationNAR330C0.33RRM_5
COADchr150200959Silentrs138724011S308S0.31
COADchr150201113Missense_MutationNAG360R0.28RRM_5
COADchr150201089Missense_MutationnovelA352T0.07RRM_5
COADchr150144975Missense_MutationnovelP10T0.15
COADchr150200808Splice_SiteNAX258_splice0.27
COADchr1502011983'UTRnovel0.1
COADchr1501063465'Flanknovel0.1
COADchr150195583Missense_MutationNAF177L0.38
COADchr150201023Missense_MutationNAR330C0.39RRM_5
COADchr150195744Missense_MutationNAR231Q0.35
COADchr150145053Nonsense_MutationNAQ36*0.31
COADchr1501063765'Flanknovel0.38
COADchr150193782Silentrs528644967P124P0.41
COADchr1501063775'Flanknovel0.08
COADchr150197434Missense_MutationnovelD247G0.08
DLBCchr1501091565'UTRnovel0.59
ESCAchr150195646SilentnovelP198P0.09
ESCAchr150197548Intronnovel0.54
ESCAchr150145144Missense_MutationnovelF66C0.07
ESCAchr1501063765'Flanknovel0.16
ESCAchr1502012383'UTRnovel0.26
GBMchr150145095Missense_Mutationrs116391279V50I0.23
GBMchr150193888Missense_MutationnovelT160A0.19
GBMchr150200864Missense_MutationnovelT277P0.08
GBMchr150195684Missense_MutationNAN211I0.28
HNSCchr150197511Intronnovel0.08
HNSCchr1501091565'UTRnovel0.09
HNSCchr150145030Missense_MutationnovelN28S0.34
HNSCchr1501091885'UTRnovel0.17
HNSCchr150197560Intronnovel0.26
HNSCchr150195680Missense_MutationnovelA210S0.36
HNSCchr150201024Missense_MutationNAR330H0.14RRM_5
HNSCchr1501091255'UTRnovel0.58
HNSCchr150177102Silentrs766623314G88G0.33
HNSCchr150193781Missense_MutationnovelP124L0.14
HNSCchr150201124SilentnovelL363L0.33
HNSCchr150197450Missense_MutationnovelM252I0.33
HNSCchr150195646Frame_Shift_InsnovelS199Kfs*530.61
HNSCchr150193882In_Frame_DelnovelI159_I163del0.13
HNSCchr150193822Missense_Mutationrs199932597G138S0.43
KICHchr150193879Missense_Mutationrs138779266R157C0.08
KIRCchr150145187Missense_MutationnovelD80E0.05
LGGchr150177132Missense_MutationnovelK98N0.11
LIHCchr1500481505'UTRnovel0.5
LIHCchr1501063535'Flanknovel0.51
LUADchr150201169Missense_MutationNAH378Q0.29RRM_5
LUADchr150145128Nonsense_MutationnovelE61*0.13
LUADchr150193828Frame_Shift_DelnovelT142Pfs*20.18
LUADchr1501063535'Flanknovel0.47
LUADchr150201010Silentrs769519214N325N0.1
LUADchr150200858Missense_MutationnovelP275T0.13
LUADchr150200859Missense_MutationnovelP275Q0.13
LUADchr150145109SilentnovelP54P0.33
LUADchr150145000Missense_MutationnovelS18Y0.13
LUADchr150145001SilentnovelS18S0.14
LUADchr150195586SilentnovelI178I0.44
LUADchr150145066Missense_MutationNAT40N0.18
LUADchr150197516IntronNA0.27
LUADchr150193892Nonsense_MutationnovelS161*0.45
LUADchr150145084Missense_MutationNAT46I0.25
LUADchr1501091045'UTRnovel0.55
LUADchr150200837Missense_MutationNAA268S0.15
LUADchr150193825Missense_MutationnovelL139I0.17
LUADchr150195657Missense_MutationnovelT202K0.23
LUSCchr150145128Nonsense_MutationnovelE61*0.42
LUSCchr150193900SilentnovelL164L0.4
LUSCchr150145142SilentnovelL65L0.2
LUSCchr150197521Intronnovel0.15
LUSCchr150200959Silentrs138724011S308S0.09
LUSCchr150193880Missense_Mutationrs200396874R157H0.21
LUSCchr150177153SilentnovelN105N0.13
LUSCchr1501063905'Flanknovel0.13
LUSCchr150197511Intronnovel0.34
LUSCchr150195593Missense_MutationNAD181N0.38
LUSCchr150177127Missense_MutationNAP97A0.18
LUSCchr150195746Missense_Mutationrs763739803R232C0.21
LUSCchr150195747Missense_Mutationrs761620230R232L0.21
LUSCchr1501039895'Flanknovel0.57
LUSCchr150201073SilentnovelT346T0.36
LUSCchr150200952Missense_MutationnovelP306H0.58
LUSCchr150145184Missense_MutationnovelR79S0.14
LUSCchr150195586SilentnovelI178I0.36
LUSCchr150177155Missense_MutationnovelT106N0.11
OVchr150201026Missense_MutationnovelD331Y0.05RRM_5
OVchr150201028Frame_Shift_DelnovelF332Sfs*140.04RRM_5
OVchr150197558Intronnovel0.15
OVchr150200914SilentnovelT293T0.24
OVchr150195733SilentnovelQ227Q0.09
PAADchr1501091655'UTRnovel0.29
PAADchr150197430Missense_MutationnovelL246M0.09
PRADchr150177155Missense_Mutationrs758825213T106I0.3
READchr150201175SilentNAS380S0.44
READchr150201087Missense_MutationNAA351V0.26RRM_5
SARCchr150109964Intronnovel0.28
SKCMchr150145156Missense_MutationNAG70D0.12
SKCMchr150145135Missense_MutationnovelR63K0.05
SKCMchr150145136SilentnovelR63R0.05
SKCMchr1501063555'Flanknovel0.33
SKCMchr150177106Missense_MutationnovelG90R0.24
SKCMchr150201028Frame_Shift_DelnovelF332Sfs*140.68RRM_5
SKCMchr150201147Missense_MutationNAS371F0.23RRM_5
SKCMchr150145018Missense_MutationnovelP24L0.31
SKCMchr150193895Missense_MutationNAR162Q0.25
SKCMchr150201113Missense_MutationNAG360R0.63RRM_5
SKCMchr1502011833'UTRnovel0.54
SKCMchr150201049SilentnovelK338K0.29
SKCMchr150177143Missense_MutationnovelK102T0.4
SKCMchr150195737Missense_MutationNAP229S0.13
SKCMchr150195744Missense_MutationNAR231Q0.5
SKCMchr150145148SilentNAG67G0.37
SKCMchr150200870Missense_MutationnovelD279N0.49
SKCMchr150177163Missense_MutationnovelG109R0.32
SKCMchr150193782Silentrs528644967P124P0.43
SKCMchr150201023Missense_MutationNAR330C0.29RRM_5
SKCMchr150201066Missense_MutationNAT344I0.16RRM_5
SKCMchr150200932SilentnovelI299I0.4
SKCMchr1501063945'Flanknovel0.29
SKCMchr150195573Missense_MutationNAG174E0.28
SKCMchr150109961Intronnovel0.36
SKCMchr150145164Missense_MutationNAE73K0.9
SKCMchr150201137SilentnovelL368L0.53
SKCMchr150193853Missense_MutationNAL148P0.27
SKCMchr150195659Missense_MutationNAE203K0.09
SKCMchr150145125Missense_MutationNAE60K0.96
SKCMchr150193895Missense_MutationNAR162Q0.42
SKCMchr150145014Missense_MutationNAG23R0.41
SKCMchr150195682SilentnovelA210A0.41
SKCMchr150200856Missense_MutationnovelS274F0.39
SKCMchr1501090775'UTRnovel0.23
SKCMchr150193854SilentNAL148L0.14
STADchr150193874Missense_MutationNAY155C0.04
STADchr150200850Missense_MutationnovelR272K0.41
STADchr1501091655'UTRnovel0.41
STADchr150193822Missense_MutationnovelG138C0.15
STADchr1502012013'UTRnovel0.31
STADchr150193782Silentrs528644967P124P0.38
STADchr150201120Missense_Mutationrs377132231R362H0.33RRM_5
STADchr150193821Silentrs374149997S137S0.22
STADchr150193822Missense_Mutationrs199932597G138S0.27
STADchr150145010SilentNAS21S0.35
STADchr150195587Missense_MutationNAR179C0.24
STADchr150144974Missense_MutationNAE9D0.28
STADchr150177155Missense_MutationNAT106S0.46
STADchr150193888Missense_MutationnovelT160A0.38
STADchr150201024Missense_MutationNAR330H0.12RRM_5
TGCTchr1502012393'UTRnovel0.08
UCECchr1501039795'Flanknovel0.34
UCECchr1501063635'FlankNA0.32
UCECchr1501091315'UTRnovel0.23
UCECchr1501091315'UTRnovel0.36
UCECchr1501063375'Flanknovel0.45
UCECchr150193868Missense_MutationNAS153L0.56
UCECchr150145176Missense_MutationnovelL77F0.35
UCECchr150193825Missense_MutationnovelL139I0.31
UCECchr150197489Intronnovel0.39
UCECchr150195563Missense_MutationNAV171M0.22
UCECchr150193810Missense_MutationNAL134F0.26
UCECchr1501090735'UTRnovel0.19
UCECchr150193862Missense_MutationnovelL151R0.08
UCECchr150177179Missense_MutationnovelT114I0.13
UCECchr1501063815'Flanknovel0.41
UCECchr150109195SilentnovelV2V0.27
UCECchr150197490Intronnovel0.35
UCECchr1501063835'Flanknovel0.07
UCECchr1501091425'UTRnovel0.42
UCECchr150145145Silentrs754162796F66F0.24
UCECchr150109839Intronnovel0.33
UCECchr1502014733'Flanknovel0.33
UCECchr150201177Nonstop_MutationNA*381Lext*110.09
UCECchr1501090815'UTRnovel0.46
UCECchr150200868Missense_Mutationrs765189019I278T0.43
UCECchr1502012533'UTRnovel0.25
UCECchr150193782Silentrs528644967P124P0.54
UCECchr1501091025'UTRnovel0.13
UCECchr1501091655'UTRnovel0.34
UCECchr150193767Splice_RegionnovelV119V0.27
UCECchr150193874Missense_MutationNAY155C0.08
UCECchr150200945Missense_MutationnovelL304M0.2
UCECchr150201164Missense_MutationnovelA377T0.33RRM_5
UCECchr1501039645'Flanknovel0.36
UCECchr150200984Missense_MutationnovelF317V0.09
UCECchr1502012213'UTRrs2020159470.25
UCECchr150201055Silentrs764075721F340F0.21
UCECchr150193836SilentnovelT142T0.28
UCECchr1502012353'UTRnovel0.25
UCECchr150144979Missense_MutationnovelQ11R0.29
UCECchr1501091315'UTRnovel0.21
UCECchr150195677Missense_MutationNAF209V0.44
UCECchr1502012643'UTRnovel0.25
UCECchr150177166Missense_MutationnovelL110I0.36
UCECchr150201010Silentrs769519214N325N0.58
UCECchr1502012353'UTRnovel0.4

Copy Number Variations (CNVs)
CancerTypeFreq Q-value

Survival Analysis
CancerP-value Q-value
THYM0.039

Kaplan-Meier Survival Analysis

MESO0.012

Kaplan-Meier Survival Analysis

ACC0.0078

Kaplan-Meier Survival Analysis

SKCM0.00066

Kaplan-Meier Survival Analysis

PAAD0.0034

Kaplan-Meier Survival Analysis

BLCA0.039

Kaplan-Meier Survival Analysis

CESC0.01

Kaplan-Meier Survival Analysis

LIHC0.012

Kaplan-Meier Survival Analysis

LGG0.00019

Kaplan-Meier Survival Analysis

LUAD0.005

Kaplan-Meier Survival Analysis

Drugs

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Eesembl ID



Cell lines and drugs in GSE70138 or GSE92742

  • Description
  • RBDs
  • Literatures
  • Expression
  • Transcripts
  • Gene Model
  • Phenotypes
  • GWAS
  • PPI
  • Paralogs
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000162374 (Gene tree)
Gene ID
1996
Gene Symbol
ELAVL4
Alias
PNEM|HUD
Full Name
ELAV like RNA binding protein 4
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Plus strand
Length
155,773 bases
Position
chr1:50,048,014-50,203,786
Accession
3315
RBP type
canonical RBP
Summary
(ELAV Like RNA Binding Protein 4) is a Protein Coding gene. Diseases associated with ELAVL4 include Hallucinogen Abuse and Sensory Peripheral Neuropathy. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is ELAVL2.
RNA binding domains(RBDs)
Protein IDDomain Pfam IDE-value Domain number Total number
ENSP00000360889RRM_5PF13893.67.3e-1312
ENSP00000360889RRM_5PF13893.67.3e-1322
ENSP00000360892RRM_5PF13893.67.5e-1312
ENSP00000360892RRM_5PF13893.67.5e-1322
ENSP00000399939RRM_5PF13893.67.8e-1312
ENSP00000399939RRM_5PF13893.67.8e-1322
ENSP00000360884RRM_5PF13893.68e-1312
ENSP00000360884RRM_5PF13893.68e-1322
ENSP00000360888RRM_5PF13893.68.4e-1312
ENSP00000360888RRM_5PF13893.68.4e-1322
ENSP00000360886RRM_5PF13893.69.2e-1312
ENSP00000360886RRM_5PF13893.69.2e-1322
ENSP00000349594RRM_5PF13893.61.2e-1212
ENSP00000349594RRM_5PF13893.61.2e-1222
ENSP00000360892RRM_1PF00076.225e-6513
ENSP00000360892RRM_1PF00076.225e-6523
ENSP00000360892RRM_1PF00076.225e-6533
ENSP00000360889RRM_1PF00076.225e-6513
ENSP00000360889RRM_1PF00076.225e-6523
ENSP00000360889RRM_1PF00076.225e-6533
ENSP00000399939RRM_1PF00076.225.2e-6513
ENSP00000399939RRM_1PF00076.225.2e-6523
ENSP00000399939RRM_1PF00076.225.2e-6533
ENSP00000360884RRM_1PF00076.225.2e-6513
ENSP00000360884RRM_1PF00076.225.2e-6523
ENSP00000360884RRM_1PF00076.225.2e-6533
ENSP00000360888RRM_1PF00076.226e-6513
ENSP00000360888RRM_1PF00076.226e-6523
ENSP00000360888RRM_1PF00076.226e-6533
ENSP00000360886RRM_1PF00076.226.3e-6513
ENSP00000360886RRM_1PF00076.226.3e-6523
ENSP00000360886RRM_1PF00076.226.3e-6533
ENSP00000349594RRM_1PF00076.227.7e-6513
ENSP00000349594RRM_1PF00076.227.7e-6523
ENSP00000349594RRM_1PF00076.227.7e-6533

Literatures on RNA binding capacity
PIDTitleArticle TimeAuthorDoi
11711535HuD, a neuronal-specific RNA-binding protein, increases the in vivo stability of MYCN RNA.J Biol Chem2002 Jan 18Manohar CF-
10848602HuD RNA recognition motifs play distinct roles in the formation of a stable complex with AU-rich RNA.Mol Cell Biol2000 JulPark S-
9045688The Elav-like proteins bind to a conserved regulatory element in the 3'-untranslated region of GAP-43 mRNA.J Biol Chem1997 Mar 7Chung S-
11573004Posttranscriptional regulation of gene expression in learning by the neuronal ELAV-like mRNA-stabilizing proteins.Proc Natl Acad Sci U S A2001 Sep 25Quattrone A-
21288476Microtubule association of a neuronal RNA-binding protein HuD through its binding to the light chain of MAP1B.Biochimie2011 MayFujiwara Ydoi: 10.1016/j.biochi.2011.01.008
24036060Neuroserpin up-regulation in the Alzheimer's disease brain is associated with elevated thyroid hormone receptor--and-beta;1 and HuD expression.Neurochem Int2013 NovSubhadra Bdoi: 10.1016/j.neuint.2013.08.010
28560387Reciprocal antagonistic regulation of N-myc mRNA by miR17 and the neuronal-specific RNA-binding protein HuD.Oncol Rep2017 JulSamaraweera Ldoi: 10.3892/or.2017.5664
7541976Hu antigens: reactivity with Hu antibodies, tumor expression, and major immunogenic sites.Ann Neurol1995 JulManley GT-
9815574Neuron-specific hel-N1 and HuD as novel molecular markers of neuroblastoma: a correlation of HuD messenger RNA levels with favorable prognostic features.Clin Cancer Res1997 OctBall NS-
9729424Expression of mRNA for the elav-like neural-specific RNA binding protein, HuD, during nervous system development.Brain Res Dev Brain Res1998 Aug 8Clayton GH-
1655278HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal.Cell1991 Oct 18Szabo A-
9516855HuD, a neuronal-specific RNA-binding protein, is a potential regulator of MYCN expression in human neuroblastoma cells.Eur J Cancer1997 OctRoss RA-
9524251Gene organization and chromosome location of the neural-specific RNA binding protein Elavl4.Gene1998 Feb 27Inman MV-
8982120The HuD paraneoplastic protein shares immunogenic regions between PEM/PSN patients and several strains and species of experimental animals.J Neuroimmunol1996 DecSillevis Smitt P-
8619556Expression of Hel-N1 and Hel-N2 in small-cell lung carcinoma.Ann Neurol1996 MayKing PH-
8053656Autoantibodies against the Hel-N1 RNA-binding protein among patients with lung carcinoma: an association with type I anti-neuronal nuclear antibodies.Ann Neurol1994 AugDropcho EJ-
8036161GRSF-1: a poly(A)+ mRNA binding protein which interacts with a conserved G-rich element.Nucleic Acids Res1994 Jun 25Qian Z-
16927307The RNA-binding protein HuD: a regulator of neuronal differentiation, maintenance and plasticity.Bioessays2006 AugDeschenes-Furry J-
12605686The 3'-UTR of the mRNA coding for the major protein kinase C substrate MARCKS contains a novel CU-rich element interacting with the mRNA stabilizing factors HuD and HuR.Eur J Biochem2003 JanWein G-
12468554Post-transcriptional regulation of acetylcholinesterase mRNAs in nerve growth factor-treated PC12 cells by the RNA-binding protein HuD.J Biol Chem2003 Feb 21Deschenes-Furry J-
12384599Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins.Nucleic Acids Res2002 Oct 15Kasashima K-
12034726Poly(A) tail length-dependent stabilization of GAP-43 mRNA by the RNA-binding protein HuD.J Biol Chem2002 Aug 2Beckel-Mitchener AC-
12000840HuD binds to three AU-rich sequences in the 3'-UTR of neuroserpin mRNA and promotes the accumulation of neuroserpin mRNA and protein.Nucleic Acids Res2002 May 15Cuadrado A-
12006625Ectopic expression of Drosophila ELAV and human HuD in Drosophila wing disc cells reveals functional distinctions and similarities.J Cell Sci2002 Jun 1Toba G-
11948657Role of HuD and other RNA-binding proteins in neural development and plasticity.J Neurosci Res2002 Apr 15Perrone-Bizzozero N-
11259113Overexpression of HuD accelerates neurite outgrowth and increases GAP-43 mRNA expression in cortical neurons and retinoic acid-induced embryonic stem cells in vitro.Exp Neurol2001 AprAnderson KD-
10710437RNA-binding analyses of HuC and HuD with the VEGF and c-myc 3'-untranslated regions using a novel ELISA-based assay.Nucleic Acids Res2000 Apr 1King PH-
10620013Cytoplasmic localization is required for the mammalian ELAV-like protein HuD to induce neuronal differentiation.Genes Cells1999 NovKasashima K-
16278682Loss of one HuD allele on chromosome #1p selects for amplification of the N-myc proto-oncogene in human neuroblastoma cells.Oncogene2006 Feb 2Grandinetti KB-
16242680Role of ELAV-like RNA-binding proteins HuD and HuR in the post-transcriptional regulation of acetylcholinesterase in neurons and skeletal muscle cells.Chem Biol Interact2005 Dec 15Deschenes-Furry J-
15827745Association between the neuron-specific RNA-binding protein ELAVL4 and Parkinson disease.Hum Genet2005 JunNoureddine MA-
16801526HuD distribution changes in response to heat shock but not neurotrophic stimulation.J Histochem Cytochem2006 OctBurry RW-
15358174TAP/NXF1, the primary mRNA export receptor, specifically interacts with a neuronal RNA-binding protein HuD.Biochem Biophys Res Commun2004 Aug 20Saito K-
14745023Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory.Proc Natl Acad Sci U S A2004 Feb 3Pascale A-
20159993Promotion of exon 6 inclusion in HuD pre-mRNA by Hu protein family members.Nucleic Acids Res2010 JunWang Hdoi: 10.1093/nar/gkq028
20064466The ELAV protein HuD stimulates cap-dependent translation in a Poly(A)- and eIF4A-dependent manner.Mol Cell2009 Dec 25Fukao Adoi: 10.1016/j.molcel.2009.11.013.
20047656A computational screen for site selective A-to-I editing detects novel sites in neuron specific Hu proteins.BMC Bioinformatics2010 Jan 4Enstero Mdoi: 10.1186/1471-2105-11-6.
19846595Novel recognition motifs and biological functions of the RNA-binding protein HuD revealed by genome-wide identification of its targets.Nucleic Acids Res2010 JanBolognani Fdoi: 10.1093/nar/gkp863
19014379Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain.J Neurochem2008 DecTiruchinapalli DMdoi: 10.1111/j.1471-4159.2008.05718.x
18493953Alterations in mossy fiber physiology and GAP-43 expression and function in transgenic mice overexpressing HuD.Hippocampus2008Tanner DCdoi: 10.1002/hipo.20442.
22895702Characterization of multiple exon 1 variants in mammalian HuD mRNA and neuron-specific transcriptional control via neurogenin 2.J Neurosci2012 Aug 15Bronicki LMdoi: 10.1523/JNEUROSCI.2247-12.2012.
17234598The RNA-binding protein HuD binds acetylcholinesterase mRNA in neurons and regulates its expression after axotomy.J Neurosci2007 Jan 17Deschenes-Furry J-
17035636A nuclear function of Hu proteins as neuron-specific alternative RNA processing regulators.Mol Biol Cell2006 DecZhu H-
23383270HuD promotes BDNF expression in brain neurons via selective stabilization of the BDNF long 3'UTR mRNA.PLoS One2013Allen Mdoi: 10.1371/journal.pone.0055718
22075994Functional and direct interaction between the RNA binding protein HuD and active Akt1.Nucleic Acids Res2012 MarFujiwara Tdoi: 10.1093/nar/gkr979
22004431Increased expression of axogenesis-related genes and mossy fibre length in dentate granule cells from adult HuD overexpressor mice.ASN Neuro2011Perrone-Bizzozero NIdoi: 10.1042/AN20110015.
21652774Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits.Proc Natl Acad Sci U S A2011 Jun 21Akten Bdoi: 10.1073/pnas.1104928108
21088113HuD interacts with survival motor neuron protein and can rescue spinal muscular atrophy-like neuronal defects.Hum Mol Genet2011 Feb 1Hubers Ldoi: 10.1093/hmg/ddq500
25692578HuD interacts with Bdnf mRNA and is essential for activity-induced BDNF synthesis in dendrites.PLoS One2015 Feb 18Vanevski Fdoi: 10.1371/journal.pone.0117264
24857657HuD regulates coding and noncoding RNA to induce APP-A-and-beta; processing.Cell Rep2014 Jun 12Kang MJdoi: 10.1016/j.celrep.2014.04.050
24658850RNA-binding proteins in neurological diseases.Sci China Life Sci2014 AprZhou H-
24599466Prenatal deletion of the RNA-binding protein HuD disrupts postnatal cortical circuit maturation and behavior.J Neurosci2014 Mar 5DeBoer EMdoi: 10.1523/JNEUROSCI.3703-13.2014.
23836929Degradation of high affinity HuD targets releases Kv1.1 mRNA from miR-129 repression by mTORC1.J Cell Biol2013 Jul 8Sosanya NMdoi: 10.1083/jcb.201212089.
25818007Molecular alterations in areas generating fast ripples in an animal model of temporal lobe epilepsy.Neurobiol Dis2015 JunWinden KDdoi: 10.1016/j.nbd.2015.02.011
26305964Positive feedback between RNA-binding protein HuD and transcription factor SATB1 promotes neurogenesis.Proc Natl Acad Sci U S A2015 Sep 8Wang Fdoi: 10.1073/pnas.1513780112
25944900Mammalian Target of Rapamycin (mTOR) Tagging Promotes Dendritic Branch Variability through the Capture of Ca2+/Calmodulin-dependent Protein Kinase II -and-alpha; (CaMKII-and-alpha;) mRNAs by the RNA-binding Protein HuD.J Biol Chem2015 Jun 26Sosanya NMdoi: 10.1074/jbc.M114.599399
28739747Application of Serum ELAVL4 (HuD) Antigen Assay for Small Cell Lung Cancer Diagnosis.Anticancer Res2017 AugWang F-
28988989FUS Mutant Human Motoneurons Display Altered Transcriptome and microRNA Pathways with Implications for ALS Pathogenesis.Stem Cell Reports2017 Nov 14De Santis Rdoi: 10.1016/j.stemcr.2017.09.004
29061699HuD and the Survival Motor Neuron Protein Interact in Motoneurons and Are Essential for Motoneuron Development, Function, and mRNA Regulation.J Neurosci2017 Nov 29Hao le Tdoi: 10.1523/JNEUROSCI.1528-17.2017
29614249Elavl3 regulates neuronal polarity through the alternative splicing of an embryo-specific exon in AnkyrinG.Neurosci Res2018 OctOgawa Ydoi: 10.1016/j.neures.2018.03.008
30014466Reduced expression of the RNA-binding protein HuD in pancreatic neuroendocrine tumors correlates with low p27Kip1 levels and poor prognosis.J Pathol2018 OctKim Cdoi: 10.1002/path.5135
30028999A Translation Tuning HuDdle for Neurons.Mol Cell2018 Jul 19McMahon Mdoi: 10.1016/j.molcel.2018.07.007.
30029004HuD Is a Neural Translation Enhancer Acting on mTORC1-Responsive Genes and Counteracted by the Y3 Small Non-coding RNA.Mol Cell2018 Jul 19Tebaldi Tdoi: 10.1016/j.molcel.2018.06.032.
30377250Regulation of Kv11.1 potassium channel C-terminal isoform expression by the RNA-binding proteins HuR and HuD.J Biol Chem2018 Dec 21Gong Qdoi: 10.1074/jbc.RA118.003720
31013625RNA-Binding Proteins HuB, HuC, and HuD are Distinctly Regulated in Dorsal Root Ganglia Neurons from STZ-Sensitive Compared to STZ-Resistant Diabetic Mice.Int J Mol Sci2019 Apr 22Mustaciosu CCdoi: 10.3390/ijms20081965.
9685407p21(waf1) mRNA contains a conserved element in its 3'-untranslated region that is bound by the Elav-like mRNA-stabilizing proteins.J Biol Chem1998 Aug 7Joseph B-
20508147Signatures of RNA binding proteins globally coupled to effective microRNA target sites.Genome Res2010 AugJacobsen Adoi: 10.1101/gr.103259.109
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000492299ELAVL4-2102106--- (aa)--
ENST00000371819ELAVL4-2022467-ENSP00000360884371 (aa)-B1APY9
ENST00000371821ELAVL4-2033349XM_006710411ENSP00000360886385 (aa)XP_006710474B1APY8
ENST00000357083ELAVL4-2011442XM_011540889ENSP00000349594402 (aa)XP_011539191A0A0R4J2E6
ENST00000463650ELAVL4-208489--- (aa)--
ENST00000474675ELAVL4-209600--- (aa)--
ENST00000371823ELAVL4-2041591XM_011540895ENSP00000360888380 (aa)XP_011539197P26378
ENST00000371824ELAVL4-2053966XM_024453829ENSP00000360889366 (aa)XP_024309597P26378
ENST00000448907ELAVL4-2071951-ENSP00000399939369 (aa)-P26378
ENST00000371827ELAVL4-2063775XM_011540893ENSP00000360892366 (aa)XP_011539195P26378
ENST00000494555ELAVL4-211458--- (aa)--
Gene Model
Click here to download ENSG00000162374's gene model file
Phenotypes
ensgIDTraitpValuePubmed ID
ENSG00000162374Anthropometry8.5960000E-005-
ENSG00000162374Creatinine7.7010000E-005-
ENSG00000162374Platelet Function Tests4.0056500E-005-
ENSG00000162374Platelet Function Tests9.0948907E-006-
ENSG00000162374Insulin-Like Growth Factor Binding Proteins6E-623251661
ENSG00000162374Body Mass Index1E-825673413
ENSG00000162374Schizophrenia6E-626198764
ENSG00000162374Body Mass Index6E-925673413
GWAS
ensgIDSNPChromosomePositionSNP-risk TraitPubmedID95% CIOr or BEAT EFO ID
ENSG00000162374rs12138061150106424ASchizophrenia26198764[NR]1.06EFO_0000692
ENSG00000162374rs12092053150141357CObesity-related traits23251661[NR] ng/mL increase0.02EFO_0005118
ENSG00000162374rs12138061150106424ASchizophrenia28991256[1.04-1.08]1.057EFO_0000692
ENSG00000162374rs11583200150094148TBMI (adjusted for smoking behaviour)28443625[0.013-0.031] kg/m2 decrease0.0222EFO_0004318|EFO_0004340
ENSG00000162374rs11583200150094148TBMI (adjusted for smoking behaviour)28443625[0.0094-0.0228] kg/m2 decrease0.0161EFO_0004318|EFO_0004340
ENSG00000162374rs11583200150094148TBody mass index (joint analysis main effects and smoking interaction)28443625EFO_0004318|EFO_0004340
ENSG00000162374rs11583200150094148TBody mass index (joint analysis main effects and smoking interaction)28443625EFO_0004318|EFO_0004340
ENSG00000162374rs11583200150094148TBody mass index26426971unit decrease0.015170207EFO_0004340
ENSG00000162374rs6685278150078144?Reaction time29844566[0.006-0.0129] unit increase0.0094725EFO_0008393
ENSG00000162374rs11583200150094148CBody mass index30108127[NR] unit increase0.019EFO_0004340
ENSG00000162374rs11583200150094148CBody mass index26961502[0.011-0.027] unit increase0.019EFO_0004340
ENSG00000162374rs12022778150138323ASmoking status (ever vs never smokers)30643258[0.011-0.021] unit decrease0.015913688EFO_0004318
ENSG00000162374rs9436888150113565CAge of smoking initiation (MTAG)30643251[0.0095-0.0163] unit decrease0.0129134EFO_0005670
ENSG00000162374rs12733544150097141ACigarettes smoked per day (MTAG)30643251[0.011-0.02] unit increase0.0152603EFO_0006525
ENSG00000162374rs7515768150122210TSmoking cessation (MTAG)30643251[0.0076-0.0148] unit increase0.0112335EFO_0004319
ENSG00000162374rs11579246150093490ADepression30718901[1.025-1.04]1.033EFO_0003761
ENSG00000162374rs12138061150106424ASchizophrenia30285260[1.04-1.08]1.059EFO_0000692
ENSG00000162374rs12022778150138323CSmoking initiation (ever regular vs never regular)30643251[0.021-0.033] unit increase0.0268248EFO_0006527
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000162374's network

* RBP PPI network refers to all genes directly bind to RBP
Paralogs
Ensembl IDGene SymbolCoverageIdentiy ParalogGene SymbolCoverageIdentiy
ENSG00000162374ELAVL48841.429ENSG00000101104PABPC1L9641.429
ENSG00000162374ELAVL48835.897ENSG00000151923TIAL19136.620
ENSG00000162374ELAVL46634.118ENSG00000213516RBMXL15334.118
ENSG00000162374ELAVL46438.333ENSG00000144642RBMS37738.333
ENSG00000162374ELAVL49981.694ENSG00000196361ELAVL39981.967
ENSG00000162374ELAVL46235.821ENSG00000164548TRA2A6031.068
ENSG00000162374ELAVL45739.726ENSG00000101489CELF48930.097
ENSG00000162374ELAVL46838.889ENSG00000099622CIRBP9638.889
ENSG00000162374ELAVL49070.997ENSG00000066044ELAVL19772.222
ENSG00000162374ELAVL48940.541ENSG00000131051RBM397440.541
ENSG00000162374ELAVL48831.579ENSG00000151846PABPC36331.579
ENSG00000162374ELAVL49989.071ENSG00000107105ELAVL210094.444
ENSG00000162374ELAVL46436.111ENSG00000153250RBMS19036.111
ENSG00000162374ELAVL49435.897ENSG00000116001TIA18635.897
ENSG00000162374ELAVL48138.272ENSG00000048740CELF25938.272
ENSG00000162374ELAVL48836.145ENSG00000070756PABPC19540.323
ENSG00000162374ELAVL46534.118ENSG00000147274RBMX8634.328
ENSG00000162374ELAVL49030.726ENSG00000143368SF3B47435.294
ENSG00000162374ELAVL49340.741ENSG00000140488CELF69735.802
ENSG00000162374ELAVL47640.741ENSG00000149187CELF19431.461
ENSG00000162374ELAVL47140.741ENSG00000159409CELF36140.741
ENSG00000162374ELAVL49035.135ENSG00000100461RBM236335.135
ENSG00000162374ELAVL48730.921ENSG00000090621PABPC49735.294
Orthologs
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000162374ELAVL49993.989ENSAPOG00000020329elavl49793.496Acanthochromis_polyacanthus
ENSG00000162374ELAVL410099.740ENSAMEG00000017455ELAVL410099.740Ailuropoda_melanoleuca
ENSG00000162374ELAVL49894.460ENSACIG00000008793elavl410094.460Amphilophus_citrinellus
ENSG00000162374ELAVL48190.217ENSAOCG00000022907elavl48990.217Amphiprion_ocellaris
ENSG00000162374ELAVL46682.400ENSAOCG00000022503elavl47082.540Amphiprion_ocellaris
ENSG00000162374ELAVL410093.207ENSAPEG00000022826elavl49593.207Amphiprion_percula
ENSG00000162374ELAVL410093.478ENSATEG00000006136elavl49994.262Anabas_testudineus
ENSG00000162374ELAVL410095.288ENSACAG00000004527ELAVL410095.288Anolis_carolinensis
ENSG00000162374ELAVL410099.751ENSANAG00000030598ELAVL410099.751Aotus_nancymaae
ENSG00000162374ELAVL49993.496ENSACLG00000002786elavl49793.011Astatotilapia_calliptera
ENSG00000162374ELAVL49995.330ENSAMXG00000000687elavl49794.823Astyanax_mexicanus
ENSG00000162374ELAVL410099.730ENSBTAG00000021046ELAVL410099.730Bos_taurus
ENSG00000162374ELAVL49561.333WBGene00001368exc-77062.385Caenorhabditis_elegans
ENSG00000162374ELAVL410099.751ENSCJAG00000013725ELAVL410099.751Callithrix_jacchus
ENSG00000162374ELAVL410099.727ENSCAFG00000003927ELAVL410099.727Canis_familiaris
ENSG00000162374ELAVL410099.180ENSCAFG00020013581ELAVL410098.756Canis_lupus_dingo
ENSG00000162374ELAVL410099.730ENSCHIG00000002038ELAVL410099.730Capra_hircus
ENSG00000162374ELAVL48899.245ENSTSYG00000004130ELAVL49499.200Carlito_syrichta
ENSG00000162374ELAVL49871.309ENSCAPG00000011942-9971.309Cavia_aperea
ENSG00000162374ELAVL476100.000ENSCAPG00000005993ELAVL483100.000Cavia_aperea
ENSG00000162374ELAVL410099.740ENSCPOG00000002044-10099.740Cavia_porcellus
ENSG00000162374ELAVL49870.166ENSCPOG00000022816-9970.166Cavia_porcellus
ENSG00000162374ELAVL410099.751ENSCCAG00000024797ELAVL410099.751Cebus_capucinus
ENSG00000162374ELAVL4100100.000ENSCATG00000029867ELAVL4100100.000Cercocebus_atys
ENSG00000162374ELAVL410099.730ENSCLAG00000005476ELAVL410099.739Chinchilla_lanigera
ENSG00000162374ELAVL4100100.000ENSCSAG00000001257ELAVL4100100.000Chlorocebus_sabaeus
ENSG00000162374ELAVL410098.442ENSCHOG00000002464ELAVL410098.442Choloepus_hoffmanni
ENSG00000162374ELAVL410098.652ENSCPBG00000010017ELAVL410098.652Chrysemys_picta_bellii
ENSG00000162374ELAVL49243.548ENSCING00000009052-10043.548Ciona_intestinalis
ENSG00000162374ELAVL4100100.000ENSCANG00000043683ELAVL4100100.000Colobus_angolensis_palliatus
ENSG00000162374ELAVL410099.740ENSCGRG00001020348Elavl410099.740Cricetulus_griseus_chok1gshd
ENSG00000162374ELAVL410099.740ENSCGRG00000009162Elavl410099.740Cricetulus_griseus_crigri
ENSG00000162374ELAVL49994.262ENSCSEG00000020141elavl49793.767Cynoglossus_semilaevis
ENSG00000162374ELAVL49993.750ENSCVAG00000019080elavl410090.160Cyprinodon_variegatus
ENSG00000162374ELAVL49995.879ENSDARG00000045639elavl49195.109Danio_rerio
ENSG00000162374ELAVL410099.730ENSDNOG00000033502ELAVL410099.730Dasypus_novemcinctus
ENSG00000162374ELAVL410099.740ENSDORG00000012729Elavl410099.740Dipodomys_ordii
ENSG00000162374ELAVL49992.838ENSETEG00000013779ELAVL410092.838Echinops_telfairi
ENSG00000162374ELAVL410099.461ENSEASG00005010728ELAVL410099.461Equus_asinus_asinus
ENSG00000162374ELAVL410099.461ENSECAG00000022284ELAVL410099.461Equus_caballus
ENSG00000162374ELAVL410099.481ENSEEUG00000008766ELAVL410099.481Erinaceus_europaeus
ENSG00000162374ELAVL49995.095ENSELUG00000008025elavl49195.109Esox_lucius
ENSG00000162374ELAVL410099.740ENSFCAG00000010438ELAVL410099.740Felis_catus
ENSG00000162374ELAVL410098.652ENSFALG00000005331ELAVL410098.652Ficedula_albicollis
ENSG00000162374ELAVL410099.730ENSFDAG00000014507ELAVL410099.739Fukomys_damarensis
ENSG00000162374ELAVL410094.022ENSFHEG00000004530elavl49394.022Fundulus_heteroclitus
ENSG00000162374ELAVL49895.822ENSGMOG00000006515elavl410095.822Gadus_morhua
ENSG00000162374ELAVL410098.652ENSGALG00000010533ELAVL410098.652Gallus_gallus
ENSG00000162374ELAVL48693.968ENSGAFG00000015956elavl48493.671Gambusia_affinis
ENSG00000162374ELAVL49893.629ENSGACG00000011152elavl410093.629Gasterosteus_aculeatus
ENSG00000162374ELAVL49998.626ENSGAGG00000018269ELAVL410096.517Gopherus_agassizii
ENSG00000162374ELAVL4100100.000ENSGGOG00000000634ELAVL4100100.000Gorilla_gorilla
ENSG00000162374ELAVL49994.262ENSHBUG00000009691elavl49793.767Haplochromis_burtoni
ENSG00000162374ELAVL410099.461ENSHGLG00000000485ELAVL410099.464Heterocephalus_glaber_female
ENSG00000162374ELAVL410099.461ENSHGLG00100002567ELAVL410099.464Heterocephalus_glaber_male
ENSG00000162374ELAVL49894.737ENSHCOG00000002490elavl410094.737Hippocampus_comes
ENSG00000162374ELAVL49995.604ENSIPUG00000001381elavl49295.616Ictalurus_punctatus
ENSG00000162374ELAVL410099.730ENSSTOG00000027271ELAVL410099.730Ictidomys_tridecemlineatus
ENSG00000162374ELAVL410099.727ENSJJAG00000023099Elavl410099.739Jaculus_jaculus
ENSG00000162374ELAVL49993.496ENSKMAG00000022289elavl49393.514Kryptolebias_marmoratus
ENSG00000162374ELAVL49993.767ENSLBEG00000007096elavl49389.664Labrus_bergylta
ENSG00000162374ELAVL45298.261ENSLBEG00000015023elavl410098.261Labrus_bergylta
ENSG00000162374ELAVL410097.561ENSLACG00000008316ELAVL410097.561Latimeria_chalumnae
ENSG00000162374ELAVL49996.154ENSLOCG00000009363elavl49096.164Lepisosteus_oculatus
ENSG00000162374ELAVL410099.740ENSLAFG00000001087ELAVL410099.740Loxodonta_africana
ENSG00000162374ELAVL4100100.000ENSMFAG00000039866ELAVL4100100.000Macaca_fascicularis
ENSG00000162374ELAVL4100100.000ENSMMUG00000021933ELAVL4100100.000Macaca_mulatta
ENSG00000162374ELAVL410099.751ENSMNEG00000035576ELAVL410099.751Macaca_nemestrina
ENSG00000162374ELAVL4100100.000ENSMLEG00000028616ELAVL4100100.000Mandrillus_leucophaeus
ENSG00000162374ELAVL410093.478ENSMAMG00000004000elavl410093.478Mastacembelus_armatus
ENSG00000162374ELAVL49994.262ENSMZEG00005010690elavl49294.278Maylandia_zebra
ENSG00000162374ELAVL410098.093ENSMGAG00000010928ELAVL410097.312Meleagris_gallopavo
ENSG00000162374ELAVL410099.740ENSMAUG00000021566Elavl410099.740Mesocricetus_auratus
ENSG00000162374ELAVL4100100.000ENSMICG00000003286ELAVL4100100.000Microcebus_murinus
ENSG00000162374ELAVL410099.737ENSMOCG00000010309Elavl410099.739Microtus_ochrogaster
ENSG00000162374ELAVL410093.478ENSMMOG00000020264elavl49593.733Mola_mola
ENSG00000162374ELAVL49664.000ENSMODG00000003850-10064.000Monodelphis_domestica
ENSG00000162374ELAVL49497.561ENSMODG00000001300-10097.561Monodelphis_domestica
ENSG00000162374ELAVL49993.989ENSMALG00000016432elavl49793.496Monopterus_albus
ENSG00000162374ELAVL410099.740MGP_CAROLIEiJ_G0026289Elavl410099.740Mus_caroli
ENSG00000162374ELAVL410099.740ENSMUSG00000028546Elavl410099.740Mus_musculus
ENSG00000162374ELAVL410099.740MGP_PahariEiJ_G0028622Elavl410099.740Mus_pahari
ENSG00000162374ELAVL410099.740MGP_SPRETEiJ_G0027258Elavl410099.740Mus_spretus
ENSG00000162374ELAVL410099.737ENSMPUG00000007192ELAVL410099.737Mustela_putorius_furo
ENSG00000162374ELAVL410098.907ENSMLUG00000006226ELAVL410099.187Myotis_lucifugus
ENSG00000162374ELAVL410099.474ENSNGAG00000023123Elavl410099.474Nannospalax_galili
ENSG00000162374ELAVL4100100.000ENSNLEG00000016303ELAVL4100100.000Nomascus_leucogenys
ENSG00000162374ELAVL49996.817ENSMEUG00000007145ELAVL410096.817Notamacropus_eugenii
ENSG00000162374ELAVL410099.740ENSOPRG00000015300ELAVL410099.740Ochotona_princeps
ENSG00000162374ELAVL410099.737ENSODEG00000006770ELAVL410099.737Octodon_degus
ENSG00000162374ELAVL410093.478ENSONIG00000002360elavl410092.493Oreochromis_niloticus
ENSG00000162374ELAVL48791.322ENSOANG00000007377ELAVL410091.322Ornithorhynchus_anatinus
ENSG00000162374ELAVL49999.725ENSOCUG00000016262ELAVL49499.178Oryctolagus_cuniculus
ENSG00000162374ELAVL49994.536ENSORLG00000028487elavl49393.531Oryzias_latipes
ENSG00000162374ELAVL49994.536ENSORLG00020014277elavl49294.550Oryzias_latipes_hni
ENSG00000162374ELAVL49994.536ENSORLG00015010143elavl49294.550Oryzias_latipes_hsok
ENSG00000162374ELAVL49993.989ENSOMEG00000009988elavl49393.243Oryzias_melastigma
ENSG00000162374ELAVL410099.180ENSOGAG00000016990ELAVL410099.187Otolemur_garnettii
ENSG00000162374ELAVL410099.730ENSOARG00000004264ELAVL410099.730Ovis_aries
ENSG00000162374ELAVL4100100.000ENSPPAG00000042402ELAVL4100100.000Pan_paniscus
ENSG00000162374ELAVL410099.740ENSPPRG00000002764ELAVL410099.740Panthera_pardus
ENSG00000162374ELAVL410099.740ENSPTIG00000016727ELAVL410099.740Panthera_tigris_altaica
ENSG00000162374ELAVL4100100.000ENSPTRG00000000723ELAVL4100100.000Pan_troglodytes
ENSG00000162374ELAVL4100100.000ENSPANG00000017754ELAVL4100100.000Papio_anubis
ENSG00000162374ELAVL49995.604ENSPKIG00000006999elavl49895.068Paramormyrops_kingsleyae
ENSG00000162374ELAVL410098.383ENSPSIG00000008545ELAVL410098.383Pelodiscus_sinensis
ENSG00000162374ELAVL410093.750ENSPMGG00000022175elavl410093.750Periophthalmus_magnuspinnatus
ENSG00000162374ELAVL410079.200ENSPEMG00000021058Elavl39980.108Peromyscus_maniculatus_bairdii
ENSG00000162374ELAVL48862.963ENSPCIG00000017116-10058.491Phascolarctos_cinereus
ENSG00000162374ELAVL49994.536ENSPFOG00000004811elavl410091.964Poecilia_formosa
ENSG00000162374ELAVL410093.750ENSPLAG00000008085elavl49994.521Poecilia_latipinna
ENSG00000162374ELAVL49994.536ENSPMEG00000015619elavl49094.550Poecilia_mexicana
ENSG00000162374ELAVL49994.536ENSPREG00000018937elavl49794.038Poecilia_reticulata
ENSG00000162374ELAVL410099.730ENSPPYG00000001367ELAVL410099.730Pongo_abelii
ENSG00000162374ELAVL410099.740ENSPCAG00000008215ELAVL410099.740Procavia_capensis
ENSG00000162374ELAVL4100100.000ENSPCOG00000024957ELAVL4100100.000Propithecus_coquereli
ENSG00000162374ELAVL48898.855ENSPVAG00000003632ELAVL410084.156Pteropus_vampyrus
ENSG00000162374ELAVL410093.478ENSPNYG00000021720elavl410093.750Pundamilia_nyererei
ENSG00000162374ELAVL49995.330ENSPNAG00000017169elavl49794.823Pygocentrus_nattereri
ENSG00000162374ELAVL410099.740ENSRNOG00000023601Elavl410099.740Rattus_norvegicus
ENSG00000162374ELAVL4100100.000ENSRBIG00000043810ELAVL4100100.000Rhinopithecus_bieti
ENSG00000162374ELAVL4100100.000ENSRROG00000044786ELAVL4100100.000Rhinopithecus_roxellana
ENSG00000162374ELAVL410099.751ENSSBOG00000022965ELAVL410099.751Saimiri_boliviensis_boliviensis
ENSG00000162374ELAVL49463.953ENSSHAG00000001657-9463.953Sarcophilus_harrisii
ENSG00000162374ELAVL410098.907ENSSHAG00000013832-10098.907Sarcophilus_harrisii
ENSG00000162374ELAVL49995.604ENSSFOG00015015838elavl49795.095Scleropages_formosus
ENSG00000162374ELAVL49994.809ENSSMAG00000006881elavl49793.548Scophthalmus_maximus
ENSG00000162374ELAVL49994.262ENSSDUG00000000045elavl49293.750Seriola_dumerili
ENSG00000162374ELAVL49994.262ENSSLDG00000005260elavl49294.278Seriola_lalandi_dorsalis
ENSG00000162374ELAVL49999.735ENSSARG00000010733ELAVL410099.735Sorex_araneus
ENSG00000162374ELAVL49898.329ENSSPUG00000011636ELAVL410098.329Sphenodon_punctatus
ENSG00000162374ELAVL410093.478ENSSPAG00000018867elavl49794.262Stegastes_partitus
ENSG00000162374ELAVL410099.730ENSSSCG00000037291ELAVL410099.730Sus_scrofa
ENSG00000162374ELAVL49998.623ENSTGUG00000008597ELAVL410098.623Taeniopygia_guttata
ENSG00000162374ELAVL49894.183ENSTRUG00000000523elavl49894.183Takifugu_rubripes
ENSG00000162374ELAVL410093.207ENSTNIG00000015485elavl410093.261Tetraodon_nigroviridis
ENSG00000162374ELAVL493100.000ENSTBEG00000011730ELAVL480100.000Tupaia_belangeri
ENSG00000162374ELAVL48597.561ENSTTRG00000012441ELAVL46797.561Tursiops_truncatus
ENSG00000162374ELAVL410098.756ENSUAMG00000013026ELAVL410099.725Ursus_americanus
ENSG00000162374ELAVL410099.180ENSUMAG00000023149ELAVL410099.735Ursus_maritimus
ENSG00000162374ELAVL410099.740ENSVPAG00000011606ELAVL410099.740Vicugna_pacos
ENSG00000162374ELAVL410099.730ENSVVUG00000006175ELAVL410099.730Vulpes_vulpes
ENSG00000162374ELAVL49991.094ENSXETG00000008680elavl410091.094Xenopus_tropicalis
ENSG00000162374ELAVL49994.536ENSXMAG00000025683elavl49794.038Xiphophorus_maculatus
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0003723RNA binding1655278.TASFunction
GO:0003730mRNA 3'-UTR binding10848602.TASFunction
GO:0006396RNA processing1655278.TASProcess
GO:0006397mRNA processing10348344.TASProcess
GO:0017091AU-rich element binding10710437.IDAFunction
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