EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
19710015	The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor.	J Biol Chem	2009 Oct 16	Crawford NP	doi: 10.1074/jbc.M109.023457
25277657	Rrp1B gene polymorphism (1307T>C) in metastatic progression of breast cancer.	Tumour Biol	2015 Feb	Nanchari SR	doi: 10.1007/s13277-014-2613-6
26901824	The contribution of SIPA1 and RRP1B germline polymorphisms to breast cancer phenotype, lymph node status and survival in a group of Lithuanian young breast cancer patients.	Biomarkers	2016	Ugenskien R	doi: 10.3109/1354750X.2016.1141989
18081427	Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis.	PLoS Genet	2007 Nov	Crawford NP	-

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr21	43686719	Intron	novel		0.35
BLCA	chr21	43673911	Missense_Mutation	NA	E105K	0.85	Nop52
BLCA	chr21	43669949	Missense_Mutation	novel	D66N	0.16	Nop52
BLCA	chr21	43687743	Nonsense_Mutation	NA	E457*	0.3
BLCA	chr21	43686848	Missense_Mutation	NA	D352Y	0.28
BLCA	chr21	43687857	Missense_Mutation	novel	E495Q	0.25
BLCA	chr21	43676335	Missense_Mutation	NA	D205Y	0.1	Nop52
BLCA	chr21	43684615	Silent	NA	H318H	0.16
BLCA	chr21	43687897	Missense_Mutation	novel	Q508R	0.14
BLCA	chr21	43693284	Silent	novel	L726L	0.22
BLCA	chr21	43687682	Silent	novel	L436L	0.55
BRCA	chr21	43691501	Splice_Region	rs777598381	A694A	0.35
BRCA	chr21	43672351	Missense_Mutation	novel	N86S	0.05	Nop52
BRCA	chr21	43675156	Missense_Mutation	novel	G181E	0.76	Nop52
BRCA	chr21	43686636	Intron	novel		0.45
CESC	chr21	43690435	Missense_Mutation	rs142326213	V672I	0.2
CESC	chr21	43683342	Missense_Mutation	NA	G287V	0.27
CESC	chr21	43684577	Nonsense_Mutation	NA	R306*	0.36
CESC	chr21	43674678	Nonsense_Mutation	novel	R134*	0.2	Nop52
CESC	chr21	43687722	Missense_Mutation	novel	A450T	0.23
CESC	chr21	43672311	Missense_Mutation	NA	E73Q	0.22	Nop52
CESC	chr21	43675064	Missense_Mutation	NA	M150I	0.12	Nop52
COAD	chr21	43674642	Missense_Mutation	NA	R122C	0.44	Nop52
COAD	chr21	43687863	Missense_Mutation	novel	M497V	0.2
COAD	chr21	43672365	Nonsense_Mutation	novel	Q91*	0.23	Nop52
COAD	chr21	43686767	Intron	novel		0.1
COAD	chr21	43693228	Missense_Mutation	novel	T708A	0.26
COAD	chr21	43690361	Missense_Mutation	novel	T647I	0.44
COAD	chr21	43688221	Missense_Mutation	NA	A616V	0.24
COAD	chr21	43675152	Frame_Shift_Del	novel	*K182Rfs4**	0.5	Nop52
COAD	chr21	43686663	Intron	novel		0.38
COAD	chr21	43674642	Missense_Mutation	NA	R122C	0.1	Nop52
COAD	chr21	43676769	Silent	NA	F217F	0.13
COAD	chr21	43659706	Silent	NA	Q14Q	0.21
COAD	chr21	43687801	Missense_Mutation	rs139787661	R476Q	0.32
COAD	chr21	43676810	Missense_Mutation	rs770600078	T231M	0.18
COAD	chr21	43693229	Missense_Mutation	rs766798880	T708M	0.2
GBM	chr21	43687560	Missense_Mutation	NA	L396F	0.43
GBM	chr21	43693198	Nonsense_Mutation	novel	K698*	0.06
GBM	chr21	43687968	Missense_Mutation	rs567364998	V532I	0.26
GBM	chr21	43693272	Silent	novel	L722L	0.11
GBM	chr21	43672314	Missense_Mutation	NA	L74I	0.82	Nop52
GBM	chr21	43690338	Missense_Mutation	novel	E639D	0.18
GBM	chr21	43693246	Missense_Mutation	novel	A714T	0.08
GBM	chr21	43693320	Silent	novel	L738L	0.3
HNSC	chr21	43684635	Missense_Mutation	novel	S325C	0.08
HNSC	chr21	43687644	Nonsense_Mutation	novel	E424*	0.24
HNSC	chr21	43687871	Missense_Mutation	novel	Q499H	0.18
HNSC	chr21	43687859	Silent	novel	E495E	0.19
KIRC	chr21	43687716	Missense_Mutation	rs750553115	A448T	0.34
KIRP	chr21	43688159	Silent	novel	K595K	0.32
KIRP	chr21	43688069	Silent	NA	P565P	0.58
LAML	chr21	43673932	Silent	novel	L112L	0.27
LGG	chr21	43686760	Intron	novel		0.11
LIHC	chr21	43672310	Splice_Region	NA	E72E	0.45
LIHC	chr21	43669955	Missense_Mutation	NA	P68T	0.53	Nop52
LIHC	chr21	43674636	Missense_Mutation	NA	L120M	0.08	Nop52
LIHC	chr21	43687829	Missense_Mutation	NA	E485D	0.19
LIHC	chr21	43674636	Missense_Mutation	NA	L120M	0.32	Nop52
LUAD	chr21	43686812	Missense_Mutation	NA	I340V	0.42
LUAD	chr21	43688003	Silent	rs759780239	P543P	0.58
LUAD	chr21	43693308	In_Frame_Del	novel	S735_V739del	0.5
LUAD	chr21	43693241	Missense_Mutation	NA	R712Q	0.32
LUAD	chr21	43675069	Missense_Mutation	novel	E152V	0.31	Nop52
LUAD	chr21	43686889	Silent	novel	K365K	0.05
LUAD	chr21	43683337	Silent	rs149845147	D285D	0.19
LUAD	chr21	43687801	Missense_Mutation	novel	R476L	0.17
LUAD	chr21	43693334	Missense_Mutation	novel	P743L	0.27
LUSC	chr21	43687801	Missense_Mutation	rs139787661	R476Q	0.67
LUSC	chr21	43690306	Missense_Mutation	novel	S629G	0.47
LUSC	chr21	43675156	Missense_Mutation	NA	G181V	0.36	Nop52
LUSC	chr21	43683335	Missense_Mutation	novel	D285H	0.08
LUSC	chr21	43684578	Missense_Mutation	rs145745406	R306Q	0.3
MESO	chr21	43687974	Frame_Shift_Del	novel	*G534Hfs108**	0.08
OV	chr21	43687902	Missense_Mutation	novel	P510T	0.31
OV	chr21	43693235	Missense_Mutation	novel	P710R	0.32
OV	chr21	43684629	Missense_Mutation	rs369172517	R323H	0.7
OV	chr21	43675151	Frame_Shift_Ins	novel	*K182Efs48**	0.05	Nop52
OV	chr21	43691500	Missense_Mutation	novel	A694G	0.21
PAAD	chr21	43686744	Intron	novel		0.25
PRAD	chr21	43686783	Intron	novel		0.36
READ	chr21	43674642	Missense_Mutation	novel	R122S	0.16	Nop52
READ	chr21	43674642	Missense_Mutation	NA	R122C	0.51	Nop52
SARC	chr21	43688223	Missense_Mutation	NA	G617W	0.06
SKCM	chr21	43684636	Silent	novel	S325S	0.39
SKCM	chr21	43687993	Missense_Mutation	NA	P540L	0.17
SKCM	chr21	43687575	Silent	NA	R401R	0.24
SKCM	chr21	43675112	Silent	NA	F166F	0.28
SKCM	chr21	43675118	Silent	NA	F168F	0.39
SKCM	chr21	43683350	Missense_Mutation	NA	E290K	0.45
SKCM	chr21	43688042	Silent	NA	E556E	0.41
SKCM	chr21	43676301	Silent	NA	I193I	0.33
SKCM	chr21	43674662	Silent	NA	S128S	0.48
SKCM	chr21	43672316	Silent	rs142807935	L74L	0.45
SKCM	chr21	43674642	Missense_Mutation	NA	R122C	0.67	Nop52
SKCM	chr21	43669927	Silent	rs755303960	L58L	0.43
SKCM	chr21	43688044	Missense_Mutation	NA	G557E	0.4
SKCM	chr21	43687563	Nonsense_Mutation	NA	Q397*	0.37
SKCM	chr21	43687625	Silent	rs545313434	G417G	0.97
STAD	chr21	43687800	Missense_Mutation	rs761894254	R476W	0.27
STAD	chr21	43675152	Frame_Shift_Del	novel	*K182Rfs4**	0.08	Nop52
STAD	chr21	43690361	Frame_Shift_Del	novel	*F649Sfs26**	0.1
STAD	chr21	43676779	Missense_Mutation	NA	V221L	0.12
STAD	chr21	43676829	Frame_Shift_Del	novel	*V239Wfs18**	0.07
STAD	chr21	43688036	Silent	rs754666630	P554P	0.27
STAD	chr21	43683346	Silent	NA	T288T	0.16
STAD	chr21	43687819	Missense_Mutation	NA	A482V	0.25
THYM	chr21	43675152	Frame_Shift_Del	novel	*K182Rfs4**	0.29	Nop52
UCEC	chr21	43686831	Missense_Mutation	rs750282721	A346V	0.12
UCEC	chr21	43676828	Missense_Mutation	rs774996157	T237I	0.11
UCEC	chr21	43687634	Silent	novel	A420A	0.25
UCEC	chr21	43674642	Missense_Mutation	NA	R122C	0.33	Nop52
UCEC	chr21	43687526	Silent	NA	V384V	0.32
UCEC	chr21	43676273	Missense_Mutation	novel	L184P	0.1	Nop52
UCEC	chr21	43676769	Silent	NA	F217F	0.17
UCEC	chr21	43675050	Missense_Mutation	NA	L146V	0.16	Nop52
UCEC	chr21	43687595	Silent	novel	H407H	0.33
UCEC	chr21	43688062	Missense_Mutation	rs376489030	T563M	0.67
UCEC	chr21	43676758	Missense_Mutation	novel	R214W	0.35	Nop52
UCEC	chr21	43675035	Nonsense_Mutation	novel	R141*	0.45	Nop52
UCEC	chr21	43693423	3'UTR	novel		0.61
UCEC	chr21	43676779	Missense_Mutation	rs750667820	V221I	0.46
UCEC	chr21	43675082	Silent	novel	P156P	0.22
UCEC	chr21	43691497	Missense_Mutation	NA	T693N	0.65
UCEC	chr21	43690341	Silent	rs564010625	S640S	0.53
UCEC	chr21	43694030	3'UTR	novel		0.43
UCEC	chr21	43688186	Missense_Mutation	novel	N604K	0.52
UCEC	chr21	43676810	Missense_Mutation	rs770600078	T231M	0.3
UCEC	chr21	43676766	Silent	NA	V216V	0.46
UCEC	chr21	43673887	Missense_Mutation	novel	T97A	0.26	Nop52
UCEC	chr21	43693288	Frame_Shift_Ins	novel	*T730Hfs52**	0.26
UCEC	chr21	43690341	Silent	rs564010625	S640S	0.34
UCEC	chr21	43693241	Missense_Mutation	NA	R712Q	0.32
UCEC	chr21	43690422	Silent	novel	P667P	0.06
UCEC	chr21	43675043	Missense_Mutation	novel	K143N	0.17	Nop52
UCEC	chr21	43675151	Silent	rs751114005	V179V	0.39
UCEC	chr21	43669948	Missense_Mutation	novel	Q65H	0.39	Nop52
UCEC	chr21	43687762	Missense_Mutation	novel	P463H	0.46
UCEC	chr21	43688195	Missense_Mutation	novel	E607D	0.35
UCEC	chr21	43690327	Missense_Mutation	novel	L636M	0.33
UCEC	chr21	43690421	Missense_Mutation	novel	P667H	0.36
UCS	chr21	43687958	Silent	novel	G528G	0.48

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
OV	DEL	0.3489	0.022578
THYM	AMP	0.0163	0.24554

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.03	Kaplan-Meier Survival Analysis
SARC	0.001	Kaplan-Meier Survival Analysis
MESO	0.0001	Kaplan-Meier Survival Analysis
ACC	0.0029	Kaplan-Meier Survival Analysis
SKCM	0.00098	Kaplan-Meier Survival Analysis
ESCA	0.017	Kaplan-Meier Survival Analysis
KIRP	0.00025	Kaplan-Meier Survival Analysis
PCPG	0.016	Kaplan-Meier Survival Analysis
CESC	0.017	Kaplan-Meier Survival Analysis
READ	0.039	Kaplan-Meier Survival Analysis
UCEC	0.0044	Kaplan-Meier Survival Analysis
LGG	0.0012	Kaplan-Meier Survival Analysis
THCA	0.021	Kaplan-Meier Survival Analysis
LUAD	0.0057	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotype

GWAS

PPI

Paralog

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000160208 (Gene tree)
Gene ID: 23076
Gene Symbol: RRP1B
Alias: Nnp1|RRP1|PPP1R136|KIAA0179
Full Name: ribosomal RNA processing 1B
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Plus strand
Length: 36,532 bases
Position: chr21:43,659,548-43,696,079
Accession: 23818
Summary: (Ribosomal RNA Processing 1B) is a Protein Coding gene. Diseases associated with RRP1B include Microinvasive Gastric Cancer and Laryngeal Squamous Cell Carcinoma. An important paralog of this gene is RRP1.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000339145	Nop52	PF05997.12	4e-72	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	polyT & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000340648	RRP1B-201	5090	-	ENSP00000339145	758 (aa)	-	Q14684
ENST00000470886	RRP1B-202	4634	-	-	- (aa)	-	-

Gene Model

Click here to download 's gene model file

Phenotype

ensgID	Trait	pValue	Pubmed ID
ENSG00000160208	Eosinophilic Esophagitis	1E-7	25017104

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000160208	rs2282526	21	43660671	T	Mean corpuscular hemoglobin	27863252	[0.016-0.03] unit decrease	0.02275459	EFO_0004527
ENSG00000160208	rs2838344	21	43669996	A	Coronary artery disease	29212778	[0.019-0.041] unit increase	0.0299	EFO_0000378
ENSG00000160208	rs9306160	21	43687681	T	Diastolic blood pressure	27618447	[0.12-0.23] mmHg decrease	0.1779	EFO_0006336
ENSG00000160208	rs9306160	21	43687681	T	Systolic blood pressure	27618447	mmHg decrease	0.252	EFO_0006335
ENSG00000160208	rs7282122	21	43662484	?	Mean corpuscular hemoglobin	30595370			EFO_0004527

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000160208's network

Paralog

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000160208	RRP1B	55	50.000	ENSG00000160214	RRP1	78	65.714

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000160208	RRP1B	64	48.438	ENSAPOG00000007490	-	53	46.594	Acanthochromis_polyacanthus
ENSG00000160208	RRP1B	50	50.781	ENSAMEG00000011448	RRP1	82	50.781	Ailuropoda_melanoleuca
ENSG00000160208	RRP1B	71	81.890	ENSAMEG00000011401	RRP1B	98	63.325	Ailuropoda_melanoleuca
ENSG00000160208	RRP1B	58	48.649	ENSAOCG00000017894	-	100	56.566	Amphiprion_ocellaris
ENSG00000160208	RRP1B	64	46.322	ENSAPEG00000024150	-	53	46.467	Amphiprion_percula
ENSG00000160208	RRP1B	67	44.675	ENSATEG00000005045	-	67	46.457	Anabas_testudineus
ENSG00000160208	RRP1B	94	47.027	ENSAPLG00000004310	RRP1B	100	47.632	Anas_platyrhynchos
ENSG00000160208	RRP1B	99	44.954	ENSACAG00000017851	RRP1B	95	45.785	Anolis_carolinensis
ENSG00000160208	RRP1B	100	90.119	ENSANAG00000034889	RRP1B	100	90.250	Aotus_nancymaae
ENSG00000160208	RRP1B	100	67.546	ENSBTAG00000017418	RRP1B	100	67.546	Bos_taurus
ENSG00000160208	RRP1B	100	89.182	ENSCJAG00000017077	RRP1B	100	89.182	Callithrix_jacchus
ENSG00000160208	RRP1B	94	68.245	ENSCAFG00000010621	RRP1B	99	69.081	Canis_familiaris
ENSG00000160208	RRP1B	100	69.160	ENSCAFG00020018901	RRP1B	100	69.948	Canis_lupus_dingo
ENSG00000160208	RRP1B	100	68.997	ENSCHIG00000021519	RRP1B	100	68.997	Capra_hircus
ENSG00000160208	RRP1B	52	48.259	ENSTSYG00000012831	RRP1	84	48.980	Carlito_syrichta
ENSG00000160208	RRP1B	100	61.629	ENSCPOG00000002396	RRP1B	100	61.629	Cavia_porcellus
ENSG00000160208	RRP1B	100	90.369	ENSCCAG00000029384	RRP1B	100	90.369	Cebus_capucinus
ENSG00000160208	RRP1B	56	47.865	ENSCCAG00000029828	RRP1	80	51.031	Cebus_capucinus
ENSG00000160208	RRP1B	100	95.778	ENSCATG00000017423	RRP1B	100	95.778	Cercocebus_atys
ENSG00000160208	RRP1B	100	64.232	ENSCLAG00000005622	RRP1B	100	64.277	Chinchilla_lanigera
ENSG00000160208	RRP1B	55	45.035	ENSCLAG00000011639	RRP1	83	48.196	Chinchilla_lanigera
ENSG00000160208	RRP1B	100	95.778	ENSCSAG00000007961	RRP1B	100	95.778	Chlorocebus_sabaeus
ENSG00000160208	RRP1B	80	48.697	ENSCHOG00000002426	-	87	49.349	Choloepus_hoffmanni
ENSG00000160208	RRP1B	99	52.842	ENSCPBG00000010310	RRP1B	98	51.967	Chrysemys_picta_bellii
ENSG00000160208	RRP1B	100	95.119	ENSCANG00000040952	RRP1B	100	95.119	Colobus_angolensis_palliatus
ENSG00000160208	RRP1B	100	65.526	ENSCGRG00001023882	-	100	65.526	Cricetulus_griseus_chok1gshd
ENSG00000160208	RRP1B	100	65.921	ENSCGRG00001010889	-	100	65.921	Cricetulus_griseus_chok1gshd
ENSG00000160208	RRP1B	94	65.132	ENSCGRG00000001553	Rrp1b	97	65.042	Cricetulus_griseus_crigri
ENSG00000160208	RRP1B	59	54.945	ENSCSEG00000020711	-	78	54.945	Cynoglossus_semilaevis
ENSG00000160208	RRP1B	100	67.323	ENSDNOG00000032774	RRP1B	100	67.759	Dasypus_novemcinctus
ENSG00000160208	RRP1B	58	48.884	ENSDNOG00000019880	RRP1	82	52.267	Dasypus_novemcinctus
ENSG00000160208	RRP1B	93	61.313	ENSDORG00000005496	Rrp1b	100	62.011	Dipodomys_ordii
ENSG00000160208	RRP1B	100	61.924	ENSETEG00000019489	RRP1B	100	61.924	Echinops_telfairi
ENSG00000160208	RRP1B	100	74.211	ENSEASG00005001687	RRP1B	100	74.211	Equus_asinus_asinus
ENSG00000160208	RRP1B	100	74.211	ENSECAG00000018018	RRP1B	100	74.211	Equus_caballus
ENSG00000160208	RRP1B	63	52.344	ENSELUG00000015885	-	89	48.485	Esox_lucius
ENSG00000160208	RRP1B	100	69.737	ENSFCAG00000010272	RRP1B	100	69.960	Felis_catus
ENSG00000160208	RRP1B	92	45.205	ENSFALG00000002024	RRP1B	100	45.330	Ficedula_albicollis
ENSG00000160208	RRP1B	96	62.791	ENSFDAG00000010899	RRP1B	96	62.927	Fukomys_damarensis
ENSG00000160208	RRP1B	57	46.420	ENSFDAG00000013728	RRP1	86	47.030	Fukomys_damarensis
ENSG00000160208	RRP1B	64	44.144	ENSFHEG00000016314	-	61	44.144	Fundulus_heteroclitus
ENSG00000160208	RRP1B	62	49.091	ENSGMOG00000001953	-	67	49.091	Gadus_morhua
ENSG00000160208	RRP1B	50	59.530	ENSGALG00000035696	RRP1B	100	46.556	Gallus_gallus
ENSG00000160208	RRP1B	99	34.771	ENSGACG00000001438	rrp1	79	42.424	Gasterosteus_aculeatus
ENSG00000160208	RRP1B	100	50.963	ENSGAGG00000000375	RRP1B	100	51.990	Gopherus_agassizii
ENSG00000160208	RRP1B	100	99.604	ENSGGOG00000012069	RRP1B	100	99.604	Gorilla_gorilla
ENSG00000160208	RRP1B	55	49.403	ENSGGOG00000000173	RRP1	80	52.507	Gorilla_gorilla
ENSG00000160208	RRP1B	99	64.529	ENSHGLG00000004968	RRP1B	100	65.177	Heterocephalus_glaber_female
ENSG00000160208	RRP1B	91	68.406	ENSHGLG00100002232	RRP1B	99	57.958	Heterocephalus_glaber_male
ENSG00000160208	RRP1B	64	47.656	ENSHCOG00000018388	-	60	47.656	Hippocampus_comes
ENSG00000160208	RRP1B	60	46.610	ENSIPUG00000000673	-	73	44.591	Ictalurus_punctatus
ENSG00000160208	RRP1B	57	47.926	ENSSTOG00000011116	RRP1	86	51.157	Ictidomys_tridecemlineatus
ENSG00000160208	RRP1B	99	71.011	ENSSTOG00000011790	RRP1B	96	71.711	Ictidomys_tridecemlineatus
ENSG00000160208	RRP1B	100	60.598	ENSJJAG00000021279	Rrp1b	100	60.988	Jaculus_jaculus
ENSG00000160208	RRP1B	64	46.761	ENSKMAG00000005539	rrp1	75	46.358	Kryptolebias_marmoratus
ENSG00000160208	RRP1B	50	54.242	ENSLACG00000017332	-	99	42.377	Latimeria_chalumnae
ENSG00000160208	RRP1B	88	66.324	ENSLAFG00000000766	RRP1B	99	66.074	Loxodonta_africana
ENSG00000160208	RRP1B	100	95.778	ENSMFAG00000039152	RRP1B	100	95.778	Macaca_fascicularis
ENSG00000160208	RRP1B	58	46.841	ENSMFAG00000003202	RRP1	80	51.989	Macaca_fascicularis
ENSG00000160208	RRP1B	100	92.480	ENSMMUG00000000104	RRP1B	100	92.480	Macaca_mulatta
ENSG00000160208	RRP1B	58	46.352	ENSMMUG00000012304	RRP1	80	51.302	Macaca_mulatta
ENSG00000160208	RRP1B	100	95.646	ENSMNEG00000034269	RRP1B	100	95.646	Macaca_nemestrina
ENSG00000160208	RRP1B	58	46.841	ENSMNEG00000031210	RRP1	80	51.989	Macaca_nemestrina
ENSG00000160208	RRP1B	100	91.853	ENSMLEG00000040044	RRP1B	99	95.944	Mandrillus_leucophaeus
ENSG00000160208	RRP1B	50	60.417	ENSMGAG00000014591	RRP1B	100	46.819	Meleagris_gallopavo
ENSG00000160208	RRP1B	100	63.289	ENSMAUG00000021508	Rrp1b	100	63.289	Mesocricetus_auratus
ENSG00000160208	RRP1B	100	78.421	ENSMICG00000004686	RRP1B	100	78.553	Microcebus_murinus
ENSG00000160208	RRP1B	58	48.438	ENSMICG00000004700	RRP1	96	48.214	Microcebus_murinus
ENSG00000160208	RRP1B	100	62.681	ENSMOCG00000001117	Rrp1b	100	62.812	Microtus_ochrogaster
ENSG00000160208	RRP1B	100	65.314	ENSMODG00000021033	RRP1B	100	65.314	Monodelphis_domestica
ENSG00000160208	RRP1B	100	61.711	MGP_CAROLIEiJ_G0021376	Rrp1b	100	61.629	Mus_caroli
ENSG00000160208	RRP1B	58	39.759	ENSMUSG00000061032	Rrp1	78	44.845	Mus_musculus
ENSG00000160208	RRP1B	100	60.944	ENSMUSG00000058392	Rrp1b	100	61.387	Mus_musculus
ENSG00000160208	RRP1B	100	63.732	MGP_PahariEiJ_G0023695	Rrp1b	100	63.732	Mus_pahari
ENSG00000160208	RRP1B	100	61.649	MGP_SPRETEiJ_G0022290	Rrp1b	100	61.649	Mus_spretus
ENSG00000160208	RRP1B	84	62.911	ENSMPUG00000009810	RRP1B	99	63.067	Mustela_putorius_furo
ENSG00000160208	RRP1B	99	72.063	ENSMLUG00000007738	RRP1B	99	71.932	Myotis_lucifugus
ENSG00000160208	RRP1B	100	66.579	ENSNGAG00000021073	Rrp1b	100	66.579	Nannospalax_galili
ENSG00000160208	RRP1B	100	93.008	ENSNLEG00000001490	RRP1B	100	93.008	Nomascus_leucogenys
ENSG00000160208	RRP1B	55	49.165	ENSNLEG00000034734	RRP1	80	51.979	Nomascus_leucogenys
ENSG00000160208	RRP1B	75	86.555	ENSMEUG00000003226	-	89	86.555	Notamacropus_eugenii
ENSG00000160208	RRP1B	100	61.397	ENSODEG00000013177	RRP1B	100	61.397	Octodon_degus
ENSG00000160208	RRP1B	61	51.282	ENSONIG00000004264	rrp1	98	36.145	Oreochromis_niloticus
ENSG00000160208	RRP1B	99	51.239	ENSOANG00000006470	RRP1B	99	52.536	Ornithorhynchus_anatinus
ENSG00000160208	RRP1B	94	56.327	ENSOCUG00000025931	RRP1B	100	56.708	Oryctolagus_cuniculus
ENSG00000160208	RRP1B	65	48.413	ENSORLG00020007199	-	56	51.613	Oryzias_latipes_hni
ENSG00000160208	RRP1B	65	46.257	ENSORLG00015004425	-	56	48.000	Oryzias_latipes_hsok
ENSG00000160208	RRP1B	64	50.794	ENSOMEG00000016910	-	65	46.113	Oryzias_melastigma
ENSG00000160208	RRP1B	98	63.158	ENSOGAG00000009872	RRP1B	100	63.293	Otolemur_garnettii
ENSG00000160208	RRP1B	94	66.434	ENSOARG00000011314	RRP1B	100	66.434	Ovis_aries
ENSG00000160208	RRP1B	94	99.441	ENSPPAG00000035319	RRP1B	99	99.302	Pan_paniscus
ENSG00000160208	RRP1B	100	68.553	ENSPPRG00000010356	RRP1B	100	68.775	Panthera_pardus
ENSG00000160208	RRP1B	54	48.905	ENSPPRG00000010656	RRP1	93	47.926	Panthera_pardus
ENSG00000160208	RRP1B	81	73.086	ENSPTIG00000016894	RRP1B	97	74.074	Panthera_tigris_altaica
ENSG00000160208	RRP1B	55	50.000	ENSPTRG00000013962	RRP1	80	53.158	Pan_troglodytes
ENSG00000160208	RRP1B	100	99.340	ENSPTRG00000013958	RRP1B	100	99.340	Pan_troglodytes
ENSG00000160208	RRP1B	100	96.042	ENSPANG00000011090	RRP1B	100	96.042	Papio_anubis
ENSG00000160208	RRP1B	55	48.565	ENSPANG00000015097	RRP1	80	51.715	Papio_anubis
ENSG00000160208	RRP1B	99	52.202	ENSPSIG00000008152	RRP1B	96	52.497	Pelodiscus_sinensis
ENSG00000160208	RRP1B	100	65.349	ENSPEMG00000022490	Rrp1b	100	65.349	Peromyscus_maniculatus_bairdii
ENSG00000160208	RRP1B	100	66.230	ENSPCIG00000015513	RRP1B	100	66.230	Phascolarctos_cinereus
ENSG00000160208	RRP1B	100	37.299	ENSPFOG00000007424	-	99	37.101	Poecilia_formosa
ENSG00000160208	RRP1B	66	46.049	ENSPMEG00000007042	-	60	46.049	Poecilia_mexicana
ENSG00000160208	RRP1B	64	47.287	ENSPREG00000015673	-	59	47.287	Poecilia_reticulata
ENSG00000160208	RRP1B	100	98.549	ENSPPYG00000011470	RRP1B	100	98.549	Pongo_abelii
ENSG00000160208	RRP1B	55	48.815	ENSPPYG00000011474	RRP1	80	51.832	Pongo_abelii
ENSG00000160208	RRP1B	85	83.158	ENSPCAG00000013723	RRP1B	91	83.158	Procavia_capensis
ENSG00000160208	RRP1B	100	78.947	ENSPCOG00000017927	RRP1B	100	79.079	Propithecus_coquereli
ENSG00000160208	RRP1B	99	66.623	ENSPVAG00000001436	RRP1B	99	66.886	Pteropus_vampyrus
ENSG00000160208	RRP1B	55	57.500	ENSPNAG00000007718	-	51	44.258	Pygocentrus_nattereri
ENSG00000160208	RRP1B	100	64.163	ENSRNOG00000001194	Rrp1b	100	64.163	Rattus_norvegicus
ENSG00000160208	RRP1B	55	49.043	ENSRBIG00000032082	RRP1	80	52.116	Rhinopithecus_bieti
ENSG00000160208	RRP1B	100	91.425	ENSRBIG00000041689	RRP1B	100	91.425	Rhinopithecus_bieti
ENSG00000160208	RRP1B	100	95.910	ENSRROG00000031499	RRP1B	100	95.977	Rhinopithecus_roxellana
ENSG00000160208	RRP1B	94	86.792	ENSSBOG00000034727	RRP1B	99	86.792	Saimiri_boliviensis_boliviensis
ENSG00000160208	RRP1B	100	66.013	ENSSHAG00000017789	RRP1B	100	66.013	Sarcophilus_harrisii
ENSG00000160208	RRP1B	58	51.639	ENSSFOG00015003932	-	57	51.639	Scleropages_formosus
ENSG00000160208	RRP1B	64	48.837	ENSSMAG00000016847	-	88	46.092	Scophthalmus_maximus
ENSG00000160208	RRP1B	65	50.382	ENSSDUG00000000551	-	58	46.174	Seriola_dumerili
ENSG00000160208	RRP1B	65	50.382	ENSSLDG00000002538	-	55	49.650	Seriola_lalandi_dorsalis
ENSG00000160208	RRP1B	77	66.667	ENSSARG00000003108	-	79	66.667	Sorex_araneus
ENSG00000160208	RRP1B	100	46.144	ENSSPUG00000002834	RRP1B	100	46.500	Sphenodon_punctatus
ENSG00000160208	RRP1B	64	49.612	ENSSPAG00000005370	-	52	49.612	Stegastes_partitus
ENSG00000160208	RRP1B	100	63.588	ENSSSCG00000021698	RRP1B	100	63.588	Sus_scrofa
ENSG00000160208	RRP1B	59	51.685	ENSTNIG00000005053	rrp1	70	51.685	Tetraodon_nigroviridis
ENSG00000160208	RRP1B	77	84.615	ENSTBEG00000000422	RRP1B	100	84.615	Tupaia_belangeri
ENSG00000160208	RRP1B	100	66.359	ENSTTRG00000000723	RRP1B	100	66.798	Tursiops_truncatus
ENSG00000160208	RRP1B	100	68.021	ENSUAMG00000026765	RRP1B	100	68.021	Ursus_americanus
ENSG00000160208	RRP1B	63	82.840	ENSUMAG00000025510	RRP1B	89	82.840	Ursus_maritimus
ENSG00000160208	RRP1B	94	68.663	ENSVVUG00000024509	RRP1B	99	69.499	Vulpes_vulpes
ENSG00000160208	RRP1B	60	46.903	ENSXETG00000013683	rrp1b	66	47.181	Xenopus_tropicalis
ENSG00000160208	RRP1B	81	46.667	ENSXMAG00000023123	-	72	46.667	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000791	euchromatin	-	IEA	Component
GO:0000792	heterochromatin	-	IEA	Component
GO:0001652	granular component	20926688.	IDA	Component
GO:0003713	transcription coactivator activity	20040599.	IMP	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	19389623.19710015.20040599.20926688.23604122.24366813.26311876.27173435.28330616.29568061.	IPI	Function
GO:0005634	nucleus	16780588.	HDA	Component
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005654	nucleoplasm	-	IEA	Component
GO:0005730	nucleolus	20040599.26311876.	IDA	Component
GO:0005829	cytosol	16780588.	HDA	Component
GO:0006364	rRNA processing	21873635.	IBA	Process
GO:0006397	mRNA processing	-	IEA	Process
GO:0006915	apoptotic process	-	IEA	Process
GO:0008380	RNA splicing	-	IEA	Process
GO:0010923	negative regulation of phosphatase activity	19389623.	IDA	Process
GO:0030687	preribosome, large subunit precursor	21873635.	IBA	Component
GO:0030688	preribosome, small subunit precursor	-	IEA	Component
GO:0034260	negative regulation of GTPase activity	-	ISS	Process
GO:0043065	positive regulation of apoptotic process	20040599.	IMP	Process
GO:0043484	regulation of RNA splicing	-	ISS	Process
GO:0043923	positive regulation by host of viral transcription	26311876.	IMP	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	20040599.	IMP	Process
GO:0098586	cellular response to virus	26311876.	IDA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotype

GWAS

PPI

Paralog

Ortholog

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.