EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
24002004	MSI2 expression is decreased in grade II of gastric carcinoma.	Pathol Res Pract	2013 Nov	Emadi-Baygi M	doi: 10.1016/j.prp.2013.07.008
26673327	The Msi Family of RNA-Binding Proteins Function Redundantly as Intestinal Oncoproteins.	Cell Rep	2015 Dec 22	Li N	doi: 10.1016/j.celrep.2015.11.022
30419948	Long non-coding RNA DANCR promotes malignant phenotypes of bladder cancer cells by modulating the miR-149/MSI2 axis as a ceRNA.	J Exp Clin Cancer Res	2018 Nov 12	Zhan Y	doi: 10.1186/s13046-018-0921-1.
26775684	Musashi2 as a novel predictive biomarker for liver metastasis and poor prognosis in colorectal cancer.	Cancer Med	2016 Apr	Zong Z	doi: 10.1002/cam4.624
27600258	Musashi-2 is a novel regulator of paclitaxel sensitivity in ovarian cancer cells.	Int J Oncol	2016 Nov	Lee J	doi: 10.3892/ijo.2016.3683
27721018	Musashi 2 contributes to the stemness and chemoresistance of liver cancer stem cells via LIN28A activation.	Cancer Lett	2017 Jan 1	Fang T	doi: 10.1016/j.canlet.2016.10.007
27593929	Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer.	Oncogene	2017 Mar 23	Kang MH	doi: 10.1038/onc.2016.327
27941885	DBC2/RhoBTB2 functions as a tumor suppressor protein via Musashi-2 ubiquitination in breast cancer.	Oncogene	2017 May 18	Choi YM	doi: 10.1038/onc.2016.441
27092875	Musashi2 promotes the development and progression of pancreatic cancer by down-regulating Numb protein.	Oncotarget	2017 Feb 28	Sheng W	doi: 10.18632/oncotarget.8736
28143872	Musashi RNA-Binding Proteins as Cancer Drivers and Novel Therapeutic Targets.	Clin Cancer Res	2017 May 1	Kudinov AE	doi: 10.1158/1078-0432.CCR-16-2728
30097032	Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins.	BMC Cancer	2018 Aug 10	Lan L	doi: 10.1186/s12885-018-4704-z.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr17	57257064	Intron	novel		0.08
BLCA	chr17	57258354	Splice_Region	novel	T90T	0.25
BLCA	chr17	57652120	Missense_Mutation	novel	G250E	0.41
BLCA	chr17	57674988	Silent	novel	R269R	0.21
BLCA	chr17	57262175	Missense_Mutation	NA	R99C	0.36	RRM_1
BLCA	chr17	57616075	Missense_Mutation	novel	G215R	0.4
BLCA	chr17	57616045	Missense_Mutation	NA	Y205H	0.27
BRCA	chr17	57677030	3'UTR	novel		0.23
BRCA	chr17	57596888	Missense_Mutation	novel	E159K	0.05
BRCA	chr17	57257094	Splice_Region	NA		0.29
BRCA	chr17	57257490	Missense_Mutation	novel	K43R	0.29
CESC	chr17	57677040	3'UTR	novel		0.42
CESC	chr17	57262174	Silent	novel	P98P	0.3
CESC	chr17	57616057	Missense_Mutation	rs769598215	A209T	0.38
CESC	chr17	57675027	Silent	rs776345010	V282V	0.33
COAD	chr17	57631904	Intron	novel		0.42
COAD	chr17	57652138	Missense_Mutation	rs772529843	A256V	0.44
COAD	chr17	57616020	Silent	NA	T196T	0.38
COAD	chr17	57401423	Silent	novel	A119A	0.08
COAD	chr17	57258273	Silent	NA	G63G	0.32
COAD	chr17	57674932	Intron	novel		0.53
COAD	chr17	57652155	Nonsense_Mutation	NA	G262*	0.38
COAD	chr17	57257013	Intron	NA		0.41
GBM	chr17	57257034	Intron	novel		0.32
GBM	chr17	57257036	Intron	novel		0.28
GBM	chr17	57262183	Silent	rs574167789	A101A	0.2
GBM	chr17	57257495	Nonsense_Mutation	novel	G45*	0.49
HNSC	chr17	57262178	Nonsense_Mutation	NA	R100*	0.07	RRM_1
HNSC	chr17	57529713	Missense_Mutation	rs778326895	N148S	0.29
KIRP	chr17	57677018	Missense_Mutation	NA	G326E	0.34
LGG	chr17	57257469	Missense_Mutation	novel	S36N	0.29
LGG	chr17	57674987	Missense_Mutation	rs200547992	R269Q	0.41
LIHC	chr17	57675081	Silent	rs376818853	S300S	0.37
LIHC	chr17	57631851	Intron	novel		0.53
LIHC	chr17	57615993	Silent	rs145999502	P187P	0.13
LUAD	chr17	57262170	Missense_Mutation	novel	F97Y	0.15	RRM_1
LUAD	chr17	57616085	Splice_Site	novel	X218_splice	0.45
LUAD	chr17	57401456	Silent	rs201726045	F130F	0.27
LUAD	chr17	57675040	Missense_Mutation	novel	G287C	0.17
LUAD	chr17	57631801	Intron	novel		0.21
LUAD	chr17	57401396	Missense_Mutation	novel	K110N	0.08	RRM_1
LUAD	chr17	57675050	Missense_Mutation	novel	S290I	0.43
LUAD	chr17	57401444	Silent	NA	V126V	0.08
LUAD	chr17	57652112	Silent	rs778007624	A247A	0.11
LUSC	chr17	57616030	Missense_Mutation	rs201389280	A200T	0.25
LUSC	chr17	57615981	Missense_Mutation	NA	K183N	0.49
LUSC	chr17	57675123	Silent	novel	I314I	0.36
LUSC	chr17	57401423	Silent	novel	A119A	0.25
OV	chr17	57616065	Frame_Shift_Ins	novel	*L212Cfs158**	0.14
OV	chr17	57257508	Missense_Mutation	novel	E49A	0.1
OV	chr17	57257489	Missense_Mutation	novel	K43Q	0.09
OV	chr17	57257479	Silent	novel	D39D	0.09
PAAD	chr17	57258304	Missense_Mutation	novel	S74G	0.18	RRM_1
PRAD	chr17	57262183	Silent	rs574167789	A101A	0.08
PRAD	chr17	57675061	Missense_Mutation	rs757898294	G294R	0.43
READ	chr17	57262179	Missense_Mutation	NA	R100Q	0.4	RRM_1
SARC	chr17	57627228	Splice_Site	novel	X218_splice	0.76
SARC	chr17	57627229	Missense_Mutation	novel	G218E	0.79
SKCM	chr17	57401456	Silent	rs201726045	F130F	0.41
SKCM	chr17	57627257	Silent	NA	G227G	0.26
SKCM	chr17	57674973	Splice_Region	novel	G264G	0.3
SKCM	chr17	57257018	Intron	novel		0.42
SKCM	chr17	57674968	Splice_Region	novel		0.37
SKCM	chr17	57258271	Missense_Mutation	NA	G63S	0.33	RRM_1
SKCM	chr17	57401456	Silent	rs201726045	F130F	0.15
SKCM	chr17	57675002	Missense_Mutation	rs745388891	P274L	0.55
SKCM	chr17	57675016	Missense_Mutation	novel	P279S	0.31
SKCM	chr17	57675017	Missense_Mutation	novel	P279L	0.31
SKCM	chr17	57652104	Missense_Mutation	NA	P245S	0.33
SKCM	chr17	57401396	Silent	NA	K110K	0.48
SKCM	chr17	57529703	Missense_Mutation	novel	K145E	0.29
STAD	chr17	57631843	Intron	novel		0.25
STAD	chr17	57675070	Missense_Mutation	NA	N297D	0.29
STAD	chr17	57257046	Intron	novel		0.11
STAD	chr17	57401412	Missense_Mutation	rs369720643	G116R	0.3	RRM_1
STAD	chr17	57674966	Splice_Region	rs758834726		0.3
UCEC	chr17	57262182	Missense_Mutation	rs772710603	A101V	0.51	RRM_1
UCEC	chr17	57616057	Missense_Mutation	rs769598215	A209T	0.16
UCEC	chr17	57401423	Silent	novel	A119A	0.07
UCEC	chr17	57257492	Missense_Mutation	novel	F44L	0.21
UCEC	chr17	57257094	Splice_Region	novel		0.72
UCEC	chr17	57675083	Missense_Mutation	NA	A301V	0.39
UCEC	chr17	57675117	Silent	rs536631751	H312H	0.46
UCEC	chr17	57631791	Intron	novel		0.16
UCEC	chr17	57632172	Intron	novel		0.3
UCEC	chr17	57632019	Intron	novel		0.31
UCEC	chr17	57627242	Silent	rs549686242	F222F	0.28
UCEC	chr17	57631986	Intron	novel		0.29
UCEC	chr17	57632054	Intron	novel		0.25
UCEC	chr17	57258327	Missense_Mutation	novel	Q81H	0.19	RRM_1
UCEC	chr17	57632019	Intron	novel		0.33
UCEC	chr17	57675031	Missense_Mutation	rs766409125	D284N	0.44
UCEC	chr17	57674987	Missense_Mutation	rs200547992	R269Q	0.3
UCEC	chr17	57679579	3'UTR	novel		0.26
UCEC	chr17	57632019	Intron	novel		0.46
UCEC	chr17	57632019	Intron	novel		0.5
UCEC	chr17	57679705	3'UTR	rs535021011		0.39
UCEC	chr17	57627242	Silent	rs549686242	F222F	0.41
UCEC	chr17	57631986	Intron	novel		0.59
UCEC	chr17	57632019	Intron	novel		0.49
UCEC	chr17	57257507	Nonsense_Mutation	novel	E49*	0.38
UCEC	chr17	57631874	Intron	novel		0.38
UCEC	chr17	57652142	Silent	novel	V257V	0.46
UCEC	chr17	57632128	Intron	novel		0.1
UCEC	chr17	57679579	3'UTR	novel		0.09
UCEC	chr17	57401423	Silent	novel	A119A	0.51
UCEC	chr17	57675125	Missense_Mutation	novel	A315D	0.08
UCEC	chr17	57632019	Intron	novel		0.4
UCEC	chr17	57679761	3'UTR	novel		0.33
UCEC	chr17	57632019	Intron	novel		0.32
UCEC	chr17	57631827	Intron	novel		0.38
UCEC	chr17	57652144	Missense_Mutation	NA	A258V	0.6
UCEC	chr17	57401423	Silent	novel	A119A	0.37
UCEC	chr17	57674956	Intron	novel		0.39
UCS	chr17	57401396	Missense_Mutation	novel	K110N	0.35	RRM_1

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
DLBC	DEL	0.0417	0.18166
KIRP	AMP	0.6632	0.14801
READ	AMP	0.1697	0.15915
THCA	DEL	0.002	0.221
UVM	AMP	0.1625	0.054583

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0049	Kaplan-Meier Survival Analysis
STAD	0.00031	Kaplan-Meier Survival Analysis
ACC	0.041	Kaplan-Meier Survival Analysis
KIRP	0.031	Kaplan-Meier Survival Analysis
COAD	0.035	Kaplan-Meier Survival Analysis
PCPG	0.025	Kaplan-Meier Survival Analysis
BLCA	0.0026	Kaplan-Meier Survival Analysis
READ	0.023	Kaplan-Meier Survival Analysis
LIHC	0.04	Kaplan-Meier Survival Analysis
UVM	0.023	Kaplan-Meier Survival Analysis

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathway

Phenotype

GWAS

PPI

Paralog

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000153944 (Gene tree)
Gene ID: 124540
Gene Symbol: MSI2
Alias: N
Full Name: musashi RNA binding protein 2
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Plus strand
Length: 444,627 bases
Position: chr17:57,255,851-57,700,477
Accession: 18585
Summary: This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells. [provided by RefSeq, Apr 2016]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000313616	RRM_1	PF00076.22	5.7e-34	1	2
ENSP00000313616	RRM_1	PF00076.22	5.7e-34	2	2
ENSP00000414671	RRM_1	PF00076.22	1.1e-33	1	2
ENSP00000414671	RRM_1	PF00076.22	1.1e-33	2	2
ENSP00000284073	RRM_1	PF00076.22	1.3e-33	1	2
ENSP00000284073	RRM_1	PF00076.22	1.3e-33	2	2
ENSP00000462914	RRM_1	PF00076.22	1.5e-22	1	1
ENSP00000462264	RRM_1	PF00076.22	1.4e-14	1	1
ENSP00000392607	RRM_1	PF00076.22	3.9e-14	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	polyT & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	PolyT & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
31059735	Musashi-2 and related stem cell proteins in the mouse suprachiasmatic nucleus and their potential role in circadian rhythms.	Int J Dev Neurosci	2019 Jun	Beligala DH	doi: 10.1016/j.ijdevneu.2019.04.007
12649177	A novel gene, MSI2, encoding a putative RNA-binding protein is recurrently rearranged at disease progression of chronic myeloid leukemia and forms a fusion gene with HOXA9 as a result of the cryptic t(7;17)(p15;q23).	Cancer Res	2003 Mar 15	Barbouti A	-
25621121	Regulated genes in mesenchymal stem cells and gastric cancer.	World J Stem Cells	2015 Jan 26	Tanabe S	doi: 10.4252/wjsc.v7.i1.208.
23943854	Systems genetics of hepatocellular damage in vivo and in vitro: identification of a critical network on chromosome 11 in mouse.	Physiol Genomics	2013 Oct 16	Liebe R	doi: 10.1152/physiolgenomics.00078.2013
23667531	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	PLoS One	2013 May 7	Cox JL	doi: 10.1371/journal.pone.0062857
27593929	Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer.	Oncogene	2017 Mar 23	Kang MH	doi: 10.1038/onc.2016.327
29073938	Musashi-2, a novel oncoprotein promoting cervical cancer cell growth and invasion, is negatively regulated by p53-induced miR-143 and miR-107 activation.	J Exp Clin Cancer Res	2017 Oct 26	Dong P	doi: 10.1186/s13046-017-0617-y.
30126842	Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling.	J Biol Chem	2018 Oct 5	Duggimpudi S	doi: 10.1074/jbc.RA118.002243
30718918	Correction: Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer.	Oncogene	2019 May	Kang MH	doi: 10.1038/s41388-019-0721-x.
29290973	Human oncoprotein Musashi-2 N-terminal RNA recognition motif backbone assignment and identification of RNA-binding pocket.	Oncotarget	2017 Nov 20	Lan L	doi: 10.18632/oncotarget.22540
23776146	Specificity factors in cytoplasmic polyadenylation.	Wiley Interdiscip Rev RNA	2013 Jul-Aug	Charlesworth A	doi: 10.1002/wrna.1171.
31066120	MicroRNA-143/Musashi-2/KRAS cascade contributes positively to carcinogenesis in human bladder cancer.	Cancer Sci	2019 Jul	Tsujino T	doi: 10.1111/cas.14035
11588182	Rna-binding protein Musashi2: developmentally regulated expression in neural precursor cells and subpopulations of neurons in mammalian CNS.	J Neurosci	2001 Oct 15	Sakakibara S	-
10657706	Musashi1: an evolutionally conserved marker for CNS progenitor cells including neural stem cells.	Dev Neurosci	2000	Kaneko Y	-
22496868	Musashi2 is required for the self-renewal and pluripotency of embryonic stem cells.	PLoS One	2012	Wuebben EL	doi: 10.1371/journal.pone.0034827
21766416	Translational control in germ cell development: A role for the RNA-binding proteins Musashi-1 and Musashi-2.	IUBMB Life	2011 Sep	Gunter KM	doi: 10.1002/iub.499
21613258	Musashi 2 is a regulator of the HSC compartment identified by a retroviral insertion screen and knockout mice.	Blood	2011 Jul 21	de Andres-Aguayo L	doi: 10.1182/blood-2010-12-322081
23209605	Drosophila Rbp6 is an orthologue of vertebrate Msi-1 and Msi-2, but does not function redundantly with dMsi to regulate germline stem cell behaviour.	PLoS One	2012	Siddall NA	doi: 10.1371/journal.pone.0049810
20639863	Regulation of myeloid leukaemia by the cell-fate determinant Musashi.	Nature	2010 Aug 5	Ito T	doi: 10.1038/nature09171
28107692	RNA binding protein MSI2 positively regulates FLT3 expression in myeloid leukemia.	Leuk Res	2017 Mar	Hattori A	doi: 10.1016/j.leukres.2017.01.015
24671879	Developmental expression of Musashi-1 and Musashi-2 RNA-binding proteins during spermatogenesis: analysis of the deleterious effects of dysregulated expression.	Biol Reprod	2014 May 1	Sutherland JM	doi: 10.1095/biolreprod.113.115261
24395885	Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs.	J Exp Med	2014 Jan 13	Park SM	doi: 10.1084/jem.20130736
24076374	Musashi2 modulates K562 leukemic cell proliferation and apoptosis involving the MAPK pathway.	Exp Cell Res	2014 Jan 1	Zhang H	doi: 10.1016/j.yexcr.2013.09.009
24002004	MSI2 expression is decreased in grade II of gastric carcinoma.	Pathol Res Pract	2013 Nov	Emadi-Baygi M	doi: 10.1016/j.prp.2013.07.008
25664853	Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program.	J Clin Invest	2015 Mar 2	Park SM	doi: 10.1172/JCI78440
27034466	Genome-wide analysis of Musashi-2 targets reveals novel functions in governing epithelial cell migration.	Nucleic Acids Res	2016 May 5	Bennett CG	doi: 10.1093/nar/gkw207
27441652	RNA-binding protein Musashi2 induced by RANKL is critical for osteoclast survival.	Cell Death Dis	2016 Jul 21	Fujiwara T	doi: 10.1038/cddis.2016.213.
27454802	Human umbilical cord blood hematopoietic stem cell expansion by the RNA-binding protein Musashi-2.	Oral Dis	2017 Jul	Tran SD	doi: 10.1111/odi.12548
27121842	Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells.	Nature	2016 Apr 28	Rentas S	doi: 10.1038/nature17665.
26898884	MSI2 is required for maintaining activated myelodysplastic syndrome stem cells.	Nat Commun	2016 Feb 22	Taggart J	doi: 10.1038/ncomms10739.
26308531	Musashi-2 Silencing Exerts Potent Activity against Acute Myeloid Leukemia and Enhances Chemosensitivity to Daunorubicin.	PLoS One	2015 Aug 26	Han Y	doi: 10.1371/journal.pone.0136484
26212080	Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia.	Cell Stem Cell	2015 Aug 6	Kwon HY	doi: 10.1016/j.stem.2015.06.006
26131972	Knockout of RNA Binding Protein MSI2 Impairs Follicle Development in the Mouse Ovary: Characterization of MSI1 and MSI2 during Folliculogenesis.	Biomolecules	2015 Jun 26	Sutherland JM	doi: 10.3390/biom5031228.
25774828	Transformation of the intestinal epithelium by the MSI2 RNA-binding protein.	Nat Commun	2015 Mar 16	Wang S	doi: 10.1038/ncomms7517.
25782991	RNA binding protein Musashi-1 directly targets Msi2 and Erh during early testis germ cell development and interacts with IPO5 upon translocation to the nucleus.	FASEB J	2015 Jul	Sutherland JM	doi: 10.1096/fj.14-265868
28143872	Musashi RNA-Binding Proteins as Cancer Drivers and Novel Therapeutic Targets.	Clin Cancer Res	2017 May 1	Kudinov AE	doi: 10.1158/1078-0432.CCR-16-2728
28514443	Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia.	Nature	2017 May 25	Hattori A	doi: 10.1038/nature22314
28884822	RNA binding protein Musashi-2 regulates PIWIL1 and TBX1 in mouse spermatogenesis.	J Cell Physiol	2018 Apr	Sutherland JM	doi: 10.1002/jcp.26168
29115587	Anticancer effect of quinacrine on diffuse large Bcell lymphoma via inhibition of MSI2NUMB signaling pathway.	Mol Med Rep	2018 Jan	Yang S	doi: 10.3892/mmr.2017.7892
29556294	Musashi-2 is a prognostic marker for the survival of patients with cervical cancer.	Oncol Lett	2018 Apr	Liu Y	doi: 10.3892/ol.2018.8077
29676650	The Pluripotency Factor Musashi-2 Is a Novel Target for Lung Cancer Therapy.	Ann Am Thorac Soc	2018 Apr	Zhang MR	doi: 10.1513/AnnalsATS.201707-608MG.
30034243	MSI2 knockdown represses extrahepatic cholangiocarcinoma growth and invasion by inhibiting epithelial-mesenchymal transition.	Onco Targets Ther	2018 Jul 13	Hu F	doi: 10.2147/OTT.S170739
30419948	Long non-coding RNA DANCR promotes malignant phenotypes of bladder cancer cells by modulating the miR-149/MSI2 axis as a ceRNA.	J Exp Clin Cancer Res	2018 Nov 12	Zhan Y	doi: 10.1186/s13046-018-0921-1.
31217428	Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.	Nat Commun	2019 Jun 19	Minuesa G	doi: 10.1038/s41467-019-10523-3.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000579505	MSI2-210	577	-	-	- (aa)	-	-
ENST00000584476	MSI2-219	465	-	-	- (aa)	-	-
ENST00000442934	MSI2-204	1624	XM_011524286	ENSP00000392607	267 (aa)	XP_011522588	B4DM51
ENST00000583821	MSI2-218	548	-	-	- (aa)	-	-
ENST00000579483	MSI2-209	5141	-	-	- (aa)	-	-
ENST00000322684	MSI2-202	1860	-	ENSP00000313616	251 (aa)	-	Q96DH6
ENST00000579531	MSI2-211	472	-	-	- (aa)	-	-
ENST00000284073	MSI2-201	6364	XM_005257014	ENSP00000284073	328 (aa)	XP_005257071	Q96DH6
ENST00000579466	MSI2-208	186	-	-	- (aa)	-	-
ENST00000577241	MSI2-205	710	-	-	- (aa)	-	-
ENST00000581776	MSI2-214	493	-	ENSP00000463227	99 (aa)	-	J3QKT5
ENST00000416426	MSI2-203	1714	-	ENSP00000414671	324 (aa)	-	B4DHE8
ENST00000583705	MSI2-217	7612	-	-	- (aa)	-	-
ENST00000582772	MSI2-216	398	-	-	- (aa)	-	-
ENST00000579180	MSI2-206	1635	-	ENSP00000462264	151 (aa)	-	Q96DH6
ENST00000582453	MSI2-215	496	-	-	- (aa)	-	-
ENST00000581523	MSI2-213	534	-	-	- (aa)	-	-
ENST00000579590	MSI2-212	452	-	ENSP00000462914	140 (aa)	-	J3KTC1
ENST00000579205	MSI2-207	500	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000153944's gene model file

Pathway

Pathway ID	Pathway Name	Source
hsa03015	mRNA surveillance pathway	KEGG

Phenotype

ensgID	Trait	pValue	Pubmed ID
ENSG00000153944	Iron	8.946e-005	-
ENSG00000153944	Electrocardiography	1.111e-005	-
ENSG00000153944	Arteries	9.3240000E-005	-
ENSG00000153944	Arteries	5.3060000E-005	-
ENSG00000153944	Arteries	5.6520000E-005	-
ENSG00000153944	Arteries	4.5840000E-005	-
ENSG00000153944	Potassium	3.7770000E-005	-
ENSG00000153944	Platelet Function Tests	5.8976601E-006	-
ENSG00000153944	Platelet Function Tests	1.6541500E-005	-
ENSG00000153944	Platelet Function Tests	1.4219000E-005	-
ENSG00000153944	Platelet Function Tests	8.3463000E-006	-
ENSG00000153944	Child Development Disorders, Pervasive	3.0537600E-005	-
ENSG00000153944	Child Development Disorders, Pervasive	5.4000000E-005	-
ENSG00000153944	Schizophrenia	2E-6	26198764
ENSG00000153944	Vascular Calcification	8E-6	23870195

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000153944	rs188761458	17	57385980	T	Mean platelet volume	27863252	[0.047-0.08] unit decrease	0.06372918	EFO_0004584
ENSG00000153944	rs12938078	17	57665916	A	Schizophrenia	26198764	[NR]	1.07	EFO_0000692
ENSG00000153944	rs11079321	17	57670055	A	Coronary artery calcification	23870195	[0.082-0.238] unit decrease	0.16	EFO_0004723
ENSG00000153944	rs35065479	17	57659374	A	Schizophrenia	28991256	[1.04-1.09]	1.066	EFO_0000692
ENSG00000153944	rs116950863	17	57370570	?	Tonsillectomy	28928442	[0.09-0.229] unit decrease	0.1592	EFO_0007924
ENSG00000153944	rs16958559	17	57581872	T	Educational attainment (MTAG)	30038396	[0.0072-0.0134] unit increase	0.0103	EFO_0004784
ENSG00000153944	rs16958559	17	57581872	T	Highest math class taken (MTAG)	30038396	[0.0081-0.0159] unit increase	0.012	EFO_0004875
ENSG00000153944	rs16958559	17	57581872	T	Cognitive performance (MTAG)	30038396	[0.01-0.021] unit increase	0.0157	EFO_0008354
ENSG00000153944	rs188761458	17	57385980	T	Plateletcrit	27863252	[0.074-0.108] unit decrease	0.09090811	EFO_0007985
ENSG00000153944	rs16958559	17	57581872	T	Educational attainment (years of education)	30038396	[0.0063-0.0129] unit increase	0.0096	EFO_0004784
ENSG00000153944	rs74364822	17	57596496	T	Male-pattern baldness	30573740	[0.023-0.049] unit decrease	0.036037	EFO_0007825
ENSG00000153944	rs1815198	17	57283224	?	Age at menopause	30595370			EFO_0004704
ENSG00000153944	rs62058023	17	57259530	?	Body mass index	30595370			EFO_0004340
ENSG00000153944	rs2586222	17	57470334	?	Body mass index	30595370			EFO_0004340
ENSG00000153944	rs72833096	17	57578571	C	Educational attainment (years of education)	30038396	[0.0072-0.015] unit decrease	0.0111	EFO_0004784
ENSG00000153944	rs80093687	17	57386496	?	White blood cell count	30595370			EFO_0004308
ENSG00000153944	rs12325702	17	57369003	A	Pulse pressure	30224653	[0.1-0.17] unit increase	0.1374	EFO_0005763
ENSG00000153944	rs145821641	17	57507204	A	Rapid automised naming of pictures	30741946	[0.22-0.56] unit decrease	0.393031	EFO_0005301
ENSG00000153944	rs150497606	17	57389065	?	Eosinophil counts	30595370			EFO_0004842
ENSG00000153944	rs35065479	17	57659374	A	Schizophrenia	30285260	[1.03-1.08]	1.054	EFO_0000692
ENSG00000153944	rs16958559	17	57581872	G	Smoking initiation (ever regular vs never regular) (MTAG)	30643251	[0.0047-0.0099] unit increase	0.0073063	EFO_0006527
ENSG00000153944	rs8072058	17	57656837	T	Chronotype	30696823		1.0284985	EFO_0008328

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000153944's network

Paralog

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000153944	MSI2	87	50.000	ENSG00000135486	HNRNPA1	100	44.828
ENSG00000153944	MSI2	88	53.488	ENSG00000138668	HNRNPD	100	54.783
ENSG00000153944	MSI2	77	40.260	ENSG00000213516	RBMXL1	71	37.838
ENSG00000153944	MSI2	82	46.154	ENSG00000139675	HNRNPA1L2	61	41.758
ENSG00000153944	MSI2	61	45.000	ENSG00000234414	RBMY1A1	65	50.000
ENSG00000153944	MSI2	86	89.394	ENSG00000135097	MSI1	99	73.840
ENSG00000153944	MSI2	82	35.484	ENSG00000101489	CELF4	70	41.667
ENSG00000153944	MSI2	91	39.286	ENSG00000132819	RBM38	81	42.373
ENSG00000153944	MSI2	62	32.895	ENSG00000119705	SLIRP	84	34.375
ENSG00000153944	MSI2	97	50.526	ENSG00000197451	HNRNPAB	78	43.231
ENSG00000153944	MSI2	61	45.000	ENSG00000242389	RBMY1E	65	50.000
ENSG00000153944	MSI2	74	43.243	ENSG00000147274	RBMX	71	50.909
ENSG00000153944	MSI2	84	38.333	ENSG00000131051	RBM39	64	38.983
ENSG00000153944	MSI2	82	36.667	ENSG00000100461	RBM23	96	33.333
ENSG00000153944	MSI2	88	31.507	ENSG00000120948	TARDBP	92	31.507
ENSG00000153944	MSI2	61	45.000	ENSG00000242875	RBMY1B	65	50.000
ENSG00000153944	MSI2	75	42.667	ENSG00000102317	RBM3	89	42.857
ENSG00000153944	MSI2	83	48.052	ENSG00000071626	DAZAP1	50	41.071
ENSG00000153944	MSI2	61	45.000	ENSG00000244395	RBMY1D	65	50.000
ENSG00000153944	MSI2	67	34.118	ENSG00000090621	PABPC4	68	34.118
ENSG00000153944	MSI2	81	48.750	ENSG00000170144	HNRNPA3	69	40.756
ENSG00000153944	MSI2	75	44.000	ENSG00000099622	CIRBP	100	47.368
ENSG00000153944	MSI2	77	50.000	ENSG00000122566	HNRNPA2B1	84	37.963
ENSG00000153944	MSI2	85	41.322	ENSG00000177733	HNRNPA0	73	41.880
ENSG00000153944	MSI2	93	53.191	ENSG00000152795	HNRNPDL	85	40.769

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000153944	MSI2	97	93.227	ENSAPOG00000001658	msi2a	100	88.110	Acanthochromis_polyacanthus
ENSG00000153944	MSI2	100	100.000	ENSAMEG00000002697	MSI2	99	100.000	Ailuropoda_melanoleuca
ENSG00000153944	MSI2	93	92.143	ENSACIG00000009475	msi2a	97	75.749	Amphilophus_citrinellus
ENSG00000153944	MSI2	79	88.288	ENSAOCG00000014822	msi2a	69	76.667	Amphiprion_ocellaris
ENSG00000153944	MSI2	100	88.615	ENSAPEG00000007706	msi2a	100	88.110	Amphiprion_percula
ENSG00000153944	MSI2	97	93.227	ENSATEG00000010498	msi2a	100	88.110	Anabas_testudineus
ENSG00000153944	MSI2	100	87.500	ENSATEG00000003301	-	100	93.165	Anabas_testudineus
ENSG00000153944	MSI2	94	97.887	ENSACAG00000005452	MSI2	74	95.455	Anolis_carolinensis
ENSG00000153944	MSI2	100	100.000	ENSANAG00000037827	MSI2	100	100.000	Aotus_nancymaae
ENSG00000153944	MSI2	97	92.829	ENSACLG00000007752	msi2a	100	87.805	Astatotilapia_calliptera
ENSG00000153944	MSI2	100	93.617	ENSAMXG00000032796	msi2a	100	91.793	Astyanax_mexicanus
ENSG00000153944	MSI2	96	95.000	ENSAMXG00000010474	msi2b	97	94.667	Astyanax_mexicanus
ENSG00000153944	MSI2	97	98.354	ENSBTAG00000004406	MSI2	98	99.111	Bos_taurus
ENSG00000153944	MSI2	86	71.304	WBGene00003423	msi-1	76	60.643	Caenorhabditis_elegans
ENSG00000153944	MSI2	100	100.000	ENSCJAG00000013998	MSI2	100	100.000	Callithrix_jacchus
ENSG00000153944	MSI2	100	99.338	ENSCAFG00020025620	MSI2	81	98.746	Canis_lupus_dingo
ENSG00000153944	MSI2	100	98.476	ENSCHIG00000016580	MSI2	100	98.476	Capra_hircus
ENSG00000153944	MSI2	93	98.571	ENSCPOG00000034042	MSI2	99	95.390	Cavia_porcellus
ENSG00000153944	MSI2	100	100.000	ENSCCAG00000033927	MSI2	100	100.000	Cebus_capucinus
ENSG00000153944	MSI2	100	99.602	ENSCATG00000040879	MSI2	100	99.602	Cercocebus_atys
ENSG00000153944	MSI2	100	100.000	ENSCLAG00000014325	MSI2	100	94.798	Chinchilla_lanigera
ENSG00000153944	MSI2	100	100.000	ENSCSAG00000005633	MSI2	100	100.000	Chlorocebus_sabaeus
ENSG00000153944	MSI2	76	100.000	ENSCHOG00000008660	MSI2	83	100.000	Choloepus_hoffmanni
ENSG00000153944	MSI2	100	93.688	ENSCPBG00000009942	MSI2	96	93.688	Chrysemys_picta_bellii
ENSG00000153944	MSI2	85	72.222	ENSCING00000018579	-	99	52.838	Ciona_intestinalis
ENSG00000153944	MSI2	94	66.129	ENSCSAVG00000010397	-	75	65.772	Ciona_savignyi
ENSG00000153944	MSI2	100	100.000	ENSCANG00000036414	MSI2	100	100.000	Colobus_angolensis_palliatus
ENSG00000153944	MSI2	100	99.392	ENSCGRG00001013330	Msi2	100	99.392	Cricetulus_griseus_chok1gshd
ENSG00000153944	MSI2	100	99.692	ENSCGRG00000003141	Msi2	100	99.692	Cricetulus_griseus_crigri
ENSG00000153944	MSI2	100	79.878	ENSCSEG00000003266	-	100	79.878	Cynoglossus_semilaevis
ENSG00000153944	MSI2	92	87.912	ENSCSEG00000013549	msi2a	100	73.913	Cynoglossus_semilaevis
ENSG00000153944	MSI2	84	69.340	ENSCSEG00000013557	msi2a	83	74.227	Cynoglossus_semilaevis
ENSG00000153944	MSI2	100	88.308	ENSCVAG00000017075	msi2a	100	87.320	Cyprinodon_variegatus
ENSG00000153944	MSI2	93	92.857	ENSDARG00000033901	msi2a	100	77.320	Danio_rerio
ENSG00000153944	MSI2	93	95.714	ENSDARG00000032614	msi2b	100	100.000	Danio_rerio
ENSG00000153944	MSI2	100	94.118	ENSDNOG00000014501	MSI2	100	100.000	Dasypus_novemcinctus
ENSG00000153944	MSI2	81	100.000	ENSDORG00000028440	-	100	100.000	Dipodomys_ordii
ENSG00000153944	MSI2	78	88.832	ENSDORG00000005394	Msi2	84	87.817	Dipodomys_ordii
ENSG00000153944	MSI2	86	81.250	FBgn0260943	Rbp6	88	68.750	Drosophila_melanogaster
ENSG00000153944	MSI2	86	97.826	ENSETEG00000012450	-	64	76.316	Echinops_telfairi
ENSG00000153944	MSI2	94	76.923	ENSEBUG00000006732	msi2a	87	68.489	Eptatretus_burgeri
ENSG00000153944	MSI2	100	100.000	ENSEASG00005002965	MSI2	97	89.112	Equus_asinus_asinus
ENSG00000153944	MSI2	100	97.289	ENSECAG00000011435	MSI2	100	92.373	Equus_caballus
ENSG00000153944	MSI2	72	98.165	ENSEEUG00000007810	MSI2	100	85.375	Erinaceus_europaeus
ENSG00000153944	MSI2	96	94.167	ENSELUG00000011747	msi2a	100	89.329	Esox_lucius
ENSG00000153944	MSI2	100	92.332	ENSELUG00000001361	msi2b	93	92.332	Esox_lucius
ENSG00000153944	MSI2	100	100.000	ENSFCAG00000041686	MSI2	100	100.000	Felis_catus
ENSG00000153944	MSI2	86	86.364	ENSFCAG00000033787	-	82	80.128	Felis_catus
ENSG00000153944	MSI2	100	100.000	ENSFDAG00000016118	MSI2	100	100.000	Fukomys_damarensis
ENSG00000153944	MSI2	97	93.227	ENSFHEG00000000084	msi2a	96	93.421	Fundulus_heteroclitus
ENSG00000153944	MSI2	92	91.209	ENSGMOG00000007596	-	100	93.269	Gadus_morhua
ENSG00000153944	MSI2	100	98.457	ENSGALG00000005567	MSI2	94	98.457	Gallus_gallus
ENSG00000153944	MSI2	86	96.522	ENSGAFG00000006974	msi2a	90	94.040	Gambusia_affinis
ENSG00000153944	MSI2	100	96.053	ENSGAGG00000016542	MSI2	100	96.053	Gopherus_agassizii
ENSG00000153944	MSI2	100	100.000	ENSGGOG00000013182	MSI2	100	100.000	Gorilla_gorilla
ENSG00000153944	MSI2	97	92.829	ENSHBUG00000020800	msi2a	100	87.805	Haplochromis_burtoni
ENSG00000153944	MSI2	96	98.901	ENSHGLG00000012444	MSI2	100	85.838	Heterocephalus_glaber_female
ENSG00000153944	MSI2	83	100.000	ENSHGLG00100004028	-	89	100.000	Heterocephalus_glaber_male
ENSG00000153944	MSI2	81	100.000	ENSHGLG00100003744	MSI2	100	100.000	Heterocephalus_glaber_male
ENSG00000153944	MSI2	93	87.857	ENSHCOG00000017241	-	71	87.678	Hippocampus_comes
ENSG00000153944	MSI2	97	92.829	ENSHCOG00000000266	msi2a	97	84.911	Hippocampus_comes
ENSG00000153944	MSI2	96	94.603	ENSIPUG00000003732	msi2b	93	93.886	Ictalurus_punctatus
ENSG00000153944	MSI2	95	93.852	ENSIPUG00000021097	msi2a	100	87.195	Ictalurus_punctatus
ENSG00000153944	MSI2	93	98.571	ENSSTOG00000007884	MSI2	99	95.390	Ictidomys_tridecemlineatus
ENSG00000153944	MSI2	81	100.000	ENSJJAG00000009467	-	100	100.000	Jaculus_jaculus
ENSG00000153944	MSI2	81	88.889	ENSJJAG00000006292	-	100	88.406	Jaculus_jaculus
ENSG00000153944	MSI2	96	91.429	ENSKMAG00000009494	msi2a	96	91.720	Kryptolebias_marmoratus
ENSG00000153944	MSI2	95	84.028	ENSLBEG00000026223	-	100	68.915	Labrus_bergylta
ENSG00000153944	MSI2	97	93.227	ENSLBEG00000007061	msi2a	100	88.110	Labrus_bergylta
ENSG00000153944	MSI2	91	94.444	ENSLACG00000016798	MSI2	100	97.030	Latimeria_chalumnae
ENSG00000153944	MSI2	93	95.714	ENSLOCG00000004675	msi2b	100	84.553	Lepisosteus_oculatus
ENSG00000153944	MSI2	100	100.000	ENSMFAG00000003775	MSI2	100	100.000	Macaca_fascicularis
ENSG00000153944	MSI2	100	100.000	ENSMMUG00000002069	MSI2	100	100.000	Macaca_mulatta
ENSG00000153944	MSI2	100	100.000	ENSMNEG00000045275	MSI2	100	100.000	Macaca_nemestrina
ENSG00000153944	MSI2	100	100.000	ENSMLEG00000033888	MSI2	100	100.000	Mandrillus_leucophaeus
ENSG00000153944	MSI2	97	92.829	ENSMAMG00000002488	-	99	92.715	Mastacembelus_armatus
ENSG00000153944	MSI2	97	93.227	ENSMAMG00000010503	msi2a	100	86.585	Mastacembelus_armatus
ENSG00000153944	MSI2	100	92.378	ENSMZEG00005007676	msi2a	100	92.378	Maylandia_zebra
ENSG00000153944	MSI2	100	99.692	ENSMAUG00000003862	Msi2	100	94.236	Mesocricetus_auratus
ENSG00000153944	MSI2	100	100.000	ENSMICG00000013598	-	100	100.000	Microcebus_murinus
ENSG00000153944	MSI2	96	87.778	ENSMICG00000032913	-	100	79.580	Microcebus_murinus
ENSG00000153944	MSI2	100	100.000	ENSMOCG00000005820	Msi2	100	94.509	Microtus_ochrogaster
ENSG00000153944	MSI2	99	88.889	ENSMMOG00000008348	msi2a	91	84.858	Mola_mola
ENSG00000153944	MSI2	81	98.551	ENSMODG00000014790	MSI2	100	98.551	Monodelphis_domestica
ENSG00000153944	MSI2	100	88.615	ENSMALG00000000071	msi2a	100	93.464	Monopterus_albus
ENSG00000153944	MSI2	100	100.000	MGP_CAROLIEiJ_G0016948	Msi2	100	100.000	Mus_caroli
ENSG00000153944	MSI2	100	100.000	ENSMUSG00000069769	Msi2	100	100.000	Mus_musculus
ENSG00000153944	MSI2	100	100.000	MGP_PahariEiJ_G0018079	Msi2	100	100.000	Mus_pahari
ENSG00000153944	MSI2	100	100.000	MGP_SPRETEiJ_G0017795	Msi2	100	100.000	Mus_spretus
ENSG00000153944	MSI2	96	99.167	ENSMPUG00000015377	MSI2	98	99.556	Mustela_putorius_furo
ENSG00000153944	MSI2	96	98.333	ENSMLUG00000007865	MSI2	98	99.556	Myotis_lucifugus
ENSG00000153944	MSI2	100	100.000	ENSNGAG00000017807	Msi2	100	94.509	Nannospalax_galili
ENSG00000153944	MSI2	100	87.805	ENSNBRG00000014596	msi2a	100	87.805	Neolamprologus_brichardi
ENSG00000153944	MSI2	100	100.000	ENSNLEG00000008059	MSI2	100	100.000	Nomascus_leucogenys
ENSG00000153944	MSI2	86	97.872	ENSOPRG00000000872	-	64	88.816	Ochotona_princeps
ENSG00000153944	MSI2	100	100.000	ENSODEG00000011974	MSI2	100	94.798	Octodon_degus
ENSG00000153944	MSI2	86	96.522	ENSONIG00000001972	msi2a	84	94.040	Oreochromis_niloticus
ENSG00000153944	MSI2	95	99.099	ENSOANG00000005667	MSI2	74	99.099	Ornithorhynchus_anatinus
ENSG00000153944	MSI2	96	98.750	ENSOCUG00000010440	MSI2	99	99.556	Oryctolagus_cuniculus
ENSG00000153944	MSI2	96	92.381	ENSORLG00000009671	msi2a	95	92.675	Oryzias_latipes
ENSG00000153944	MSI2	97	93.227	ENSORLG00020021556	msi2a	100	86.585	Oryzias_latipes_hni
ENSG00000153944	MSI2	96	92.381	ENSORLG00015004592	msi2a	95	92.675	Oryzias_latipes_hsok
ENSG00000153944	MSI2	100	86.585	ENSOMEG00000000146	msi2a	98	91.694	Oryzias_melastigma
ENSG00000153944	MSI2	100	90.123	ENSOGAG00000005621	MSI2	99	95.440	Otolemur_garnettii
ENSG00000153944	MSI2	100	100.000	ENSPPAG00000037697	MSI2	100	100.000	Pan_paniscus
ENSG00000153944	MSI2	100	99.602	ENSPPRG00000001848	MSI2	100	99.602	Panthera_pardus
ENSG00000153944	MSI2	100	100.000	ENSPTIG00000021678	MSI2	96	100.000	Panthera_tigris_altaica
ENSG00000153944	MSI2	100	86.538	ENSPTIG00000021873	-	99	77.559	Panthera_tigris_altaica
ENSG00000153944	MSI2	100	100.000	ENSPTRG00000009437	MSI2	100	100.000	Pan_troglodytes
ENSG00000153944	MSI2	100	100.000	ENSPANG00000022319	MSI2	100	100.000	Papio_anubis
ENSG00000153944	MSI2	100	85.859	ENSPKIG00000017107	-	88	85.859	Paramormyrops_kingsleyae
ENSG00000153944	MSI2	96	91.209	ENSPKIG00000007038	-	96	86.061	Paramormyrops_kingsleyae
ENSG00000153944	MSI2	100	98.106	ENSPSIG00000008618	MSI2	83	98.106	Pelodiscus_sinensis
ENSG00000153944	MSI2	100	87.500	ENSPMGG00000005888	msi2a	100	87.500	Periophthalmus_magnuspinnatus
ENSG00000153944	MSI2	81	100.000	ENSPEMG00000021793	-	100	100.000	Peromyscus_maniculatus_bairdii
ENSG00000153944	MSI2	100	98.408	ENSPCIG00000006063	MSI2	100	90.395	Phascolarctos_cinereus
ENSG00000153944	MSI2	92	90.110	ENSPFOG00000019337	MSI2	92	91.429	Poecilia_formosa
ENSG00000153944	MSI2	100	82.828	ENSPLAG00000000436	msi2a	76	90.845	Poecilia_latipinna
ENSG00000153944	MSI2	79	88.288	ENSPMEG00000013247	msi2a	62	100.000	Poecilia_mexicana
ENSG00000153944	MSI2	97	93.227	ENSPREG00000000881	msi2a	99	85.671	Poecilia_reticulata
ENSG00000153944	MSI2	94	96.639	ENSPPYG00000008244	-	100	96.639	Pongo_abelii
ENSG00000153944	MSI2	72	79.793	ENSPCAG00000010552	MSI2	100	70.588	Procavia_capensis
ENSG00000153944	MSI2	94	100.000	ENSPCOG00000019195	-	100	100.000	Propithecus_coquereli
ENSG00000153944	MSI2	86	100.000	ENSPVAG00000017053	MSI2	100	90.785	Pteropus_vampyrus
ENSG00000153944	MSI2	100	92.378	ENSPNYG00000018393	msi2a	100	92.378	Pundamilia_nyererei
ENSG00000153944	MSI2	100	90.274	ENSPNAG00000000844	msi2b	100	88.754	Pygocentrus_nattereri
ENSG00000153944	MSI2	100	93.617	ENSPNAG00000014957	msi2a	100	92.097	Pygocentrus_nattereri
ENSG00000153944	MSI2	94	100.000	ENSRNOG00000025338	Msi2	100	100.000	Rattus_norvegicus
ENSG00000153944	MSI2	91	83.333	ENSRBIG00000032064	-	72	98.182	Rhinopithecus_bieti
ENSG00000153944	MSI2	94	100.000	ENSRROG00000034421	-	100	100.000	Rhinopithecus_roxellana
ENSG00000153944	MSI2	100	100.000	ENSSBOG00000026425	MSI2	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000153944	MSI2	100	98.765	ENSSHAG00000008672	MSI2	100	98.765	Sarcophilus_harrisii
ENSG00000153944	MSI2	91	97.101	ENSSFOG00015012168	msi2b	74	87.204	Scleropages_formosus
ENSG00000153944	MSI2	94	91.549	ENSSFOG00015021687	-	97	87.948	Scleropages_formosus
ENSG00000153944	MSI2	97	93.227	ENSSMAG00000018484	msi2a	100	88.110	Scophthalmus_maximus
ENSG00000153944	MSI2	100	85.987	ENSSDUG00000021968	-	99	92.053	Seriola_dumerili
ENSG00000153944	MSI2	97	93.227	ENSSDUG00000014507	msi2a	100	88.110	Seriola_dumerili
ENSG00000153944	MSI2	97	93.227	ENSSLDG00000017172	msi2a	100	88.110	Seriola_lalandi_dorsalis
ENSG00000153944	MSI2	93	76.087	ENSSLDG00000021332	-	68	76.087	Seriola_lalandi_dorsalis
ENSG00000153944	MSI2	92	93.407	ENSSPUG00000000913	-	94	94.304	Sphenodon_punctatus
ENSG00000153944	MSI2	97	93.227	ENSSPAG00000017793	msi2a	96	86.032	Stegastes_partitus
ENSG00000153944	MSI2	100	100.000	ENSSSCG00000038505	MSI2	100	100.000	Sus_scrofa
ENSG00000153944	MSI2	81	99.034	ENSTGUG00000008452	MSI2	100	99.034	Taeniopygia_guttata
ENSG00000153944	MSI2	100	87.179	ENSTRUG00000021248	msi2a	100	86.866	Takifugu_rubripes
ENSG00000153944	MSI2	91	86.957	ENSTBEG00000001241	MSI2	73	82.645	Tupaia_belangeri
ENSG00000153944	MSI2	91	100.000	ENSTTRG00000002189	MSI2	100	90.756	Tursiops_truncatus
ENSG00000153944	MSI2	100	99.602	ENSUAMG00000000700	MSI2	100	99.602	Ursus_americanus
ENSG00000153944	MSI2	95	97.203	ENSUMAG00000000505	MSI2	95	92.075	Ursus_maritimus
ENSG00000153944	MSI2	87	99.020	ENSVPAG00000006837	-	62	84.615	Vicugna_pacos
ENSG00000153944	MSI2	100	100.000	ENSVVUG00000011783	MSI2	100	98.671	Vulpes_vulpes
ENSG00000153944	MSI2	93	92.857	ENSXCOG00000006113	msi2a	89	87.500	Xiphophorus_couchianus
ENSG00000153944	MSI2	97	93.227	ENSXMAG00000000608	msi2a	100	87.320	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0005515	protein binding	25416956.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005844	polysome	21873635.	IBA	Component
GO:0008266	poly(U) RNA binding	-	IEA	Function
GO:0048864	stem cell development	-	IEA	Process
GO:1990904	ribonucleoprotein complex	21873635.	IBA	Component

Note: Click here to get the extension of tumor abbreviations.

Note: to get the extension of tumor abbreviations.