EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
12754299	Participation of kin17 protein in replication factories and in other DNA transactions mediated by high molecular weight nuclear complexes.	Mol Cancer Res	2003 May	Biard DS	-
24755081	KIN enhances stem cell-like properties to promote chemoresistance in colorectal carcinoma.	Biochem Biophys Res Commun	2014 May 23	Yu M	doi: 10.1016/j.bbrc.2014.04.057
21980430	Up-regulation of kin17 is essential for proliferation of breast cancer.	PLoS One	2011	Zeng T	doi: 10.1371/journal.pone.0025343
28346239	Elevated Expression of Kin17 in Cervical Cancer and Its Association With Cancer Cell Proliferation and Invasion.	Int J Gynecol Cancer	2017 May	Zhang Y	doi: 10.1097/IGC.0000000000000928.

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr10	7780061	Missense_Mutation	novel	R124T	0.2	Kin17_mid
BLCA	chr10	7787822	Missense_Mutation	novel	E38K	0.17
BLCA	chr10	7769224	In_Frame_Ins	novel	E263_I264insHQNL	0.04
BLCA	chr10	7775773	Silent	novel	S195S	0.2
BLCA	chr10	7756123	Missense_Mutation	novel	R380K	0.16
BLCA	chr10	7774834	Nonsense_Mutation	novel	S222*	0.38
BLCA	chr10	7774855	Missense_Mutation	NA	S215F	0.16
BLCA	chr10	7787847	Missense_Mutation	NA	Q29H	0.39
BRCA	chr10	7774842	Silent	novel	S219S	0.26
BRCA	chr10	7783144	Missense_Mutation	NA	S49C	0.23
CESC	chr10	7756048	3'UTR	novel		0.18
CESC	chr10	7763766	Frame_Shift_Ins	novel	*K292Tfs20**	0.15
COAD	chr10	7783145	Missense_Mutation	novel	S49P	0.11
COAD	chr10	7759825	Intron	rs767035598		0.5
COAD	chr10	7769287	Nonsense_Mutation	NA	E243*	0.45
COAD	chr10	7759984	Missense_Mutation	NA	R342I	0.33
COAD	chr10	7759826	Intron	rs774926423		0.53
COAD	chr10	7769330	Silent	NA	S228S	0.28
ESCA	chr10	7759826	Intron	rs774926423		0.32
GBM	chr10	7766059	Silent	novel	L281L	0.06
GBM	chr10	7755950	3'UTR	novel		0.31
GBM	chr10	7778938	Missense_Mutation	novel	L153R	0.03	Kin17_mid
HNSC	chr10	7774828	Splice_Region	novel		0.15
HNSC	chr10	7766084	Missense_Mutation	novel	R273T	0.11
KIRP	chr10	7783135	Missense_Mutation	NA	R52T	0.13	Kin17_mid
KIRP	chr10	7780152	Missense_Mutation	NA	V94L	0.38	Kin17_mid
KIRP	chr10	7769215	Splice_Site	NA	X266_splice	0.35
KIRP	chr10	7787896	Missense_Mutation	NA	A13G	0.46
LGG	chr10	7759906	Missense_Mutation	novel	T368I	0.07
LGG	chr10	7779013	Missense_Mutation	novel	C128Y	0.34	Kin17_mid
LGG	chr10	7780148	Missense_Mutation	novel	Y95C	0.04	Kin17_mid
LIHC	chr10	7756073	3'UTR	novel		0.18
LIHC	chr10	7780172	Missense_Mutation	novel	K87R	0.31	Kin17_mid
LUAD	chr10	7759932	Silent	rs751451566	S359S	0.21
LUAD	chr10	7778917	Missense_Mutation	NA	K160M	0.11	Kin17_mid
LUAD	chr10	7787942	5'UTR	novel		0.76
LUAD	chr10	7778928	Missense_Mutation	NA	E156D	0.05	Kin17_mid
LUAD	chr10	7780299	Missense_Mutation	rs762761840	R73Q	0.1	Kin17_mid
LUAD	chr10	7759949	Missense_Mutation	novel	E354Q	0.23
LUAD	chr10	7780275	Missense_Mutation	novel	R81M	0.18	Kin17_mid
LUAD	chr10	7759957	Missense_Mutation	novel	R351K	0.08
LUAD	chr10	7763758	Nonsense_Mutation	novel	G295*	0.18
LUAD	chr10	7763759	Silent	novel	L294L	0.18
LUAD	chr10	7778843	Missense_Mutation	NA	E185K	0.27
LUAD	chr10	7762458	Splice_Region	NA	P339P	0.08
LUAD	chr10	7759911	Silent	NA	S366S	0.1
LUAD	chr10	7787821	Missense_Mutation	NA	E38V	0.28
LUAD	chr10	7759902	Silent	rs144499188	I369I	0.14
LUAD	chr10	7778976	Silent	novel	Q140Q	0.06
LUAD	chr10	7766062	Missense_Mutation	NA	W280C	0.25
LUAD	chr10	7787948	5'UTR	novel		0.22
LUSC	chr10	7787875	Missense_Mutation	novel	G20V	0.37
LUSC	chr10	7756056	3'UTR	rs750505045		0.29
LUSC	chr10	7783154	Missense_Mutation	novel	M46V	0.11
LUSC	chr10	7778868	Missense_Mutation	novel	Q176H	0.15	Kin17_mid
LUSC	chr10	7787826	Silent	NA	R36R	0.21
OV	chr10	7780073	Missense_Mutation	NA	K120R	0.38	Kin17_mid
PRAD	chr10	7780176	Missense_Mutation	NA	T86P	0.28	Kin17_mid
PRAD	chr10	7766054	Missense_Mutation	NA	P283H	0.21
PRAD	chr10	7778891	Frame_Shift_Del	rs769387138	*T169Lfs9**	0.41	Kin17_mid
READ	chr10	7759913	Frame_Shift_Del	NA	*A367Yfs5**	0.33
READ	chr10	7759852	Intron	novel		0.35
READ	chr10	7759984	Missense_Mutation	NA	R342I	0.67
READ	chr10	7778955	Missense_Mutation	NA	E147D	0.38	Kin17_mid
SKCM	chr10	7780135	Silent	novel	I99I	0.28
SKCM	chr10	7778885	Missense_Mutation	NA	K171E	0.46	Kin17_mid
SKCM	chr10	7755906	3'UTR	novel		1
SKCM	chr10	7759854	Intron	novel		0.81
SKCM	chr10	7755925	3'UTR	novel		0.24
SKCM	chr10	7769276	Silent	NA	Q246Q	0.85
SKCM	chr10	7787908	Missense_Mutation	NA	P9L	0.42
SKCM	chr10	7775794	Silent	NA	V188V	0.38
SKCM	chr10	7775793	Missense_Mutation	NA	P189S	0.57
STAD	chr10	7787874	Silent	NA	G20G	0.16
STAD	chr10	7778891	Frame_Shift_Del	rs769387138	*T169Lfs9**	0.31	Kin17_mid
STAD	chr10	7756143	Splice_Site	novel	X374_splice	0.28
STAD	chr10	7774844	Missense_Mutation	NA	S219T	0.33
STAD	chr10	7778971	Missense_Mutation	NA	I142T	0.1	Kin17_mid
STAD	chr10	7759913	Frame_Shift_Del	novel	*S366Qfs11**	0.38
STAD	chr10	7778891	Frame_Shift_Del	rs769387138	*T169Lfs9**	0.1	Kin17_mid
STAD	chr10	7778891	Frame_Shift_Del	rs769387138	*T169Lfs9**	0.23	Kin17_mid
UCEC	chr10	7759979	Missense_Mutation	NA	L344I	0.17
UCEC	chr10	7763760	Missense_Mutation	novel	L294P	0.29
UCEC	chr10	7756128	Silent	NA	G378G	0.44
UCEC	chr10	7769222	Silent	novel	I264I	0.36
UCEC	chr10	7756085	Missense_Mutation	novel	A393T	0.42
UCEC	chr10	7780285	Nonsense_Mutation	novel	E78*	0.43	Kin17_mid
UCEC	chr10	7759799	Intron	novel		0.49
UCEC	chr10	7756069	3'UTR	rs374009763		0.06
UCEC	chr10	7780143	Missense_Mutation	NA	E97K	0.04	Kin17_mid
UCEC	chr10	7755986	3'UTR	novel		0.29
UCEC	chr10	7778945	Missense_Mutation	rs778349410	R151W	0.07	Kin17_mid
UCEC	chr10	7755881	3'UTR	novel		0.26
UCEC	chr10	7759826	Intron	rs774926423		0.25
UCEC	chr10	7755906	3'UTR	novel		0.33
UCEC	chr10	7759834	Intron	novel		0.41
UCEC	chr10	7769291	Silent	novel	R241R	0.27
UCEC	chr10	7755992	3'UTR	novel		0.42
UCEC	chr10	7769318	Silent	rs747671134	T232T	0.16
UCEC	chr10	7780270	Missense_Mutation	rs543372718	R83C	0.24	Kin17_mid
UCEC	chr10	7759762	Intron	novel		0.22
UCEC	chr10	7756127	Missense_Mutation	rs772662628	R379C	0.37
UCEC	chr10	7759942	Missense_Mutation	rs199577905	T356I	0.35
UCEC	chr10	7755986	3'UTR	novel		0.53
UCEC	chr10	7759923	Silent	NA	E362E	0.49
UCEC	chr10	7755986	3'UTR	novel		0.21
UCEC	chr10	7756026	3'UTR	rs113920374		0.34
UCEC	chr10	7778945	Missense_Mutation	rs778349410	R151W	0.19	Kin17_mid

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1222	0.19593
KIRC	AMP	0.0208	0.17403
MESO	DEL	0.3103	0.0040398
PAAD	DEL	0.1467	0.169
STAD	DEL	0.1156	0.13903

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0016	Kaplan-Meier Survival Analysis
KIRC	0.004	Kaplan-Meier Survival Analysis
MESO	0.041	Kaplan-Meier Survival Analysis
ACC	0.00011	Kaplan-Meier Survival Analysis
PRAD	0.02	Kaplan-Meier Survival Analysis
BRCA	0.0091	Kaplan-Meier Survival Analysis
ESCA	0.025	Kaplan-Meier Survival Analysis
KIRP	0.00095	Kaplan-Meier Survival Analysis
COAD	0.044	Kaplan-Meier Survival Analysis
BLCA	0.0012	Kaplan-Meier Survival Analysis
UCEC	0.043	Kaplan-Meier Survival Analysis
GBM	0.042	Kaplan-Meier Survival Analysis
LIHC	0.0089	Kaplan-Meier Survival Analysis
DLBC	0.018	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
CHOL	0.012	Kaplan-Meier Survival Analysis
UVM	0.025	Kaplan-Meier Survival Analysis
OV	0.047	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000151657 (Gene tree)
Gene ID: 22944
Gene Symbol: KIN
Alias: KIN17|Rts2
Full Name: Kin17 DNA and RNA binding protein
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 37,066 bases
Position: chr10:7,750,962-7,788,027
Accession: 6327
RBP type: canonical RBP
Summary: The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000368881	Kin17_mid	PF10357.9	1.4e-49	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
16636754	NMR assignment of region 51-160 of human KIN17, a DNA and RNA-binding protein.	J Biomol NMR	2006	Carlier L	-
15252136	KIN17 encodes an RNA-binding protein and is expressed during mouse spermatogenesis.	J Cell Sci	2004 Jul 15	Pinon-Lataillade G	-
18029424	Solution structure of the region 51-160 of human KIN17 reveals an atypical winged helix domain.	Protein Sci	2007 Dec	Carlier L	-
17045609	A tandem of SH3-like domains participates in RNA binding in KIN17, a human protein activated in response to genotoxics.	J Mol Biol	2006 Dec 8	le Maire A	-
24140279	Methylation of the DNA/RNA-binding protein Kin17 by METTL22 affects its association with chromatin.	J Proteomics	2014 Apr 4	Cloutier P	doi: 10.1016/j.jprot.2013.10.008
28454391	Upregulation of KIN17 is associated with non-small cell lung cancer invasiveness.	Oncol Lett	2017 Apr	Zhang Y	doi: 10.3892/ol.2017.5707
30655766	Knockdown of DNA/RNA-binding protein KIN17 promotes apoptosis of triple-negative breast cancer cells.	Oncol Lett	2019 Jan	Gao X	doi: 10.3892/ol.2018.9597
15147838	The DNA binding protein H-NS binds to and alters the stability of RNA in vitro and in vivo.	J Mol Biol	2004 Jun 4	Brescia CC	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000460089	KIN-202	613	-	-	- (aa)	-	-
ENST00000498098	KIN-205	817	-	ENSP00000473950	108 (aa)	-	S4R357
ENST00000463666	KIN-203	699	-	-	- (aa)	-	-
ENST00000471320	KIN-204	885	-	-	- (aa)	-	-
ENST00000379562	KIN-201	6348	XM_006717434	ENSP00000368881	393 (aa)	XP_006717497	O60870

Gene Model

Click here to download ENSG00000151657's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000151657	monocyte chemoattractant protein 1 (66-77)	4.6370000E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000151657's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000151657	KIN	100	75.443	ENSAPOG00000017545	kin	100	74.619	Acanthochromis_polyacanthus
ENSG00000151657	KIN	99	97.196	ENSAMEG00000009938	KIN	100	95.420	Ailuropoda_melanoleuca
ENSG00000151657	KIN	100	69.289	ENSACIG00000004254	kin	100	67.920	Amphilophus_citrinellus
ENSG00000151657	KIN	100	76.396	ENSAOCG00000017503	kin	100	76.396	Amphiprion_ocellaris
ENSG00000151657	KIN	100	76.396	ENSAPEG00000017533	kin	100	76.396	Amphiprion_percula
ENSG00000151657	KIN	100	71.392	ENSATEG00000022023	kin	100	69.543	Anabas_testudineus
ENSG00000151657	KIN	100	88.071	ENSAPLG00000008247	KIN	100	86.802	Anas_platyrhynchos
ENSG00000151657	KIN	99	82.243	ENSACAG00000004280	KIN	100	82.740	Anolis_carolinensis
ENSG00000151657	KIN	100	98.728	ENSANAG00000023418	KIN	100	98.728	Aotus_nancymaae
ENSG00000151657	KIN	100	71.537	ENSACLG00000014118	kin	100	69.367	Astatotilapia_calliptera
ENSG00000151657	KIN	100	76.650	ENSAMXG00000043472	kin	100	76.396	Astyanax_mexicanus
ENSG00000151657	KIN	99	99.065	ENSBTAG00000013925	KIN	100	97.201	Bos_taurus
ENSG00000151657	KIN	98	51.887	WBGene00013128	dxbp-1	100	45.343	Caenorhabditis_elegans
ENSG00000151657	KIN	100	98.982	ENSCJAG00000020631	KIN	100	98.982	Callithrix_jacchus
ENSG00000151657	KIN	100	95.165	ENSCAFG00000005034	KIN	100	95.420	Canis_familiaris
ENSG00000151657	KIN	100	95.420	ENSCAFG00020005737	KIN	100	95.674	Canis_lupus_dingo
ENSG00000151657	KIN	99	99.065	ENSCHIG00000012913	KIN	100	97.201	Capra_hircus
ENSG00000151657	KIN	100	96.692	ENSTSYG00000013959	KIN	100	96.692	Carlito_syrichta
ENSG00000151657	KIN	99	97.196	ENSCAPG00000007137	KIN	99	87.772	Cavia_aperea
ENSG00000151657	KIN	100	96.947	ENSCPOG00000010515	KIN	100	96.947	Cavia_porcellus
ENSG00000151657	KIN	99	98.131	ENSCCAG00000032798	KIN	100	90.840	Cebus_capucinus
ENSG00000151657	KIN	99	99.065	ENSCATG00000036456	KIN	100	96.456	Cercocebus_atys
ENSG00000151657	KIN	100	96.438	ENSCLAG00000008690	-	100	96.438	Chinchilla_lanigera
ENSG00000151657	KIN	100	65.394	ENSCLAG00000006918	-	100	64.122	Chinchilla_lanigera
ENSG00000151657	KIN	100	71.756	ENSCLAG00000009998	-	100	71.756	Chinchilla_lanigera
ENSG00000151657	KIN	100	98.728	ENSCSAG00000013458	KIN	100	98.728	Chlorocebus_sabaeus
ENSG00000151657	KIN	100	89.822	ENSCHOG00000013674	KIN	100	90.076	Choloepus_hoffmanni
ENSG00000151657	KIN	99	89.541	ENSCPBG00000019799	KIN	99	88.265	Chrysemys_picta_bellii
ENSG00000151657	KIN	99	62.404	ENSCING00000024731	-	98	61.893	Ciona_intestinalis
ENSG00000151657	KIN	99	59.079	ENSCSAVG00000009886	-	98	58.568	Ciona_savignyi
ENSG00000151657	KIN	99	98.131	ENSCANG00000009920	-	100	96.947	Colobus_angolensis_palliatus
ENSG00000151657	KIN	100	98.728	ENSCANG00000035875	-	100	98.728	Colobus_angolensis_palliatus
ENSG00000151657	KIN	100	93.639	ENSCGRG00001018259	Kin	100	93.130	Cricetulus_griseus_chok1gshd
ENSG00000151657	KIN	100	93.639	ENSCGRG00000006637	Kin	100	93.130	Cricetulus_griseus_crigri
ENSG00000151657	KIN	100	68.193	ENSCSEG00000020113	kin	100	67.939	Cynoglossus_semilaevis
ENSG00000151657	KIN	100	74.874	ENSCVAG00000020284	kin	100	72.292	Cyprinodon_variegatus
ENSG00000151657	KIN	100	75.888	ENSDARG00000045515	kin	100	75.635	Danio_rerio
ENSG00000151657	KIN	99	97.222	ENSDNOG00000009047	KIN	100	96.193	Dasypus_novemcinctus
ENSG00000151657	KIN	100	95.674	ENSDORG00000003732	Kin	100	95.674	Dipodomys_ordii
ENSG00000151657	KIN	99	51.372	FBgn0024887	kin17	99	50.882	Drosophila_melanogaster
ENSG00000151657	KIN	84	100.000	ENSETEG00000010546	KIN	100	70.229	Echinops_telfairi
ENSG00000151657	KIN	99	59.813	ENSEBUG00000007709	kin	96	59.854	Eptatretus_burgeri
ENSG00000151657	KIN	100	78.426	ENSEASG00005019250	KIN	100	78.426	Equus_asinus_asinus
ENSG00000151657	KIN	100	95.674	ENSECAG00000013570	KIN	100	95.929	Equus_caballus
ENSG00000151657	KIN	99	97.196	ENSEEUG00000010992	KIN	100	80.916	Erinaceus_europaeus
ENSG00000151657	KIN	100	72.335	ENSELUG00000006020	kin	100	72.081	Esox_lucius
ENSG00000151657	KIN	100	95.165	ENSFCAG00000000195	KIN	100	95.420	Felis_catus
ENSG00000151657	KIN	100	87.023	ENSFALG00000001842	KIN	100	86.005	Ficedula_albicollis
ENSG00000151657	KIN	100	90.250	ENSFDAG00000007791	KIN	100	91.858	Fukomys_damarensis
ENSG00000151657	KIN	95	68.932	ENSFHEG00000008764	kin	68	64.174	Fundulus_heteroclitus
ENSG00000151657	KIN	99	72.613	ENSGMOG00000003481	kin	99	68.861	Gadus_morhua
ENSG00000151657	KIN	92	89.899	ENSGALG00000030702	KIN	96	82.239	Gallus_gallus
ENSG00000151657	KIN	100	71.930	ENSGAFG00000004845	kin	100	71.106	Gambusia_affinis
ENSG00000151657	KIN	100	71.717	ENSGACG00000020107	kin	100	70.202	Gasterosteus_aculeatus
ENSG00000151657	KIN	99	89.286	ENSGAGG00000015018	KIN	100	88.235	Gopherus_agassizii
ENSG00000151657	KIN	100	99.491	ENSGGOG00000009714	KIN	100	99.491	Gorilla_gorilla
ENSG00000151657	KIN	100	73.935	ENSHBUG00000005203	kin	100	73.300	Haplochromis_burtoni
ENSG00000151657	KIN	99	98.131	ENSHGLG00000005095	KIN	100	92.621	Heterocephalus_glaber_female
ENSG00000151657	KIN	99	98.131	ENSHGLG00100009367	KIN	100	92.621	Heterocephalus_glaber_male
ENSG00000151657	KIN	100	65.239	ENSHCOG00000005077	kin	100	63.544	Hippocampus_comes
ENSG00000151657	KIN	99	76.276	ENSIPUG00000008328	kin	99	75.255	Ictalurus_punctatus
ENSG00000151657	KIN	53	79.909	ENSIPUG00000006609	-	94	79.909	Ictalurus_punctatus
ENSG00000151657	KIN	99	99.065	ENSSTOG00000026385	KIN	100	97.710	Ictidomys_tridecemlineatus
ENSG00000151657	KIN	100	95.929	ENSJJAG00000021735	Kin	100	95.929	Jaculus_jaculus
ENSG00000151657	KIN	100	74.559	ENSKMAG00000014663	kin	100	73.804	Kryptolebias_marmoratus
ENSG00000151657	KIN	100	71.465	ENSLBEG00000023197	kin	100	71.212	Labrus_bergylta
ENSG00000151657	KIN	100	81.472	ENSLACG00000009265	KIN	99	81.726	Latimeria_chalumnae
ENSG00000151657	KIN	100	77.608	ENSLOCG00000015679	kin	100	77.608	Lepisosteus_oculatus
ENSG00000151657	KIN	99	99.065	ENSLAFG00000014449	KIN	100	97.455	Loxodonta_africana
ENSG00000151657	KIN	100	98.728	ENSMFAG00000002686	KIN	100	98.728	Macaca_fascicularis
ENSG00000151657	KIN	100	98.728	ENSMMUG00000009206	KIN	100	98.728	Macaca_mulatta
ENSG00000151657	KIN	100	98.728	ENSMNEG00000042848	KIN	100	98.728	Macaca_nemestrina
ENSG00000151657	KIN	99	78.505	ENSMLEG00000032428	KIN	100	62.595	Mandrillus_leucophaeus
ENSG00000151657	KIN	100	72.796	ENSMAMG00000017791	kin	100	70.707	Mastacembelus_armatus
ENSG00000151657	KIN	100	71.537	ENSMZEG00005021704	kin	100	69.367	Maylandia_zebra
ENSG00000151657	KIN	99	88.785	ENSMGAG00000004418	KIN	100	85.423	Meleagris_gallopavo
ENSG00000151657	KIN	100	94.148	ENSMAUG00000022217	Kin	100	93.639	Mesocricetus_auratus
ENSG00000151657	KIN	100	98.148	ENSMICG00000008248	KIN	100	89.059	Microcebus_murinus
ENSG00000151657	KIN	100	94.911	ENSMOCG00000016933	Kin	100	94.148	Microtus_ochrogaster
ENSG00000151657	KIN	100	69.543	ENSMMOG00000006713	kin	100	67.766	Mola_mola
ENSG00000151657	KIN	100	90.585	ENSMODG00000016717	KIN	100	90.331	Monodelphis_domestica
ENSG00000151657	KIN	100	72.475	ENSMALG00000000864	kin	100	72.475	Monopterus_albus
ENSG00000151657	KIN	100	92.875	MGP_CAROLIEiJ_G0023167	Kin	100	92.366	Mus_caroli
ENSG00000151657	KIN	100	92.366	ENSMUSG00000037262	Kin	100	91.603	Mus_musculus
ENSG00000151657	KIN	100	92.621	MGP_PahariEiJ_G0019227	Kin	100	92.112	Mus_pahari
ENSG00000151657	KIN	100	92.366	MGP_SPRETEiJ_G0024085	Kin	100	91.603	Mus_spretus
ENSG00000151657	KIN	99	97.196	ENSMPUG00000016375	KIN	100	95.929	Mustela_putorius_furo
ENSG00000151657	KIN	99	97.196	ENSMLUG00000002261	KIN	100	95.420	Myotis_lucifugus
ENSG00000151657	KIN	100	95.165	ENSNGAG00000012802	Kin	100	94.148	Nannospalax_galili
ENSG00000151657	KIN	100	71.537	ENSNBRG00000012732	kin	100	69.521	Neolamprologus_brichardi
ENSG00000151657	KIN	100	99.746	ENSNLEG00000011891	KIN	100	99.746	Nomascus_leucogenys
ENSG00000151657	KIN	100	80.916	ENSMEUG00000014709	KIN	100	80.916	Notamacropus_eugenii
ENSG00000151657	KIN	100	90.585	ENSOPRG00000011875	KIN	100	90.585	Ochotona_princeps
ENSG00000151657	KIN	99	97.196	ENSODEG00000000102	-	100	93.893	Octodon_degus
ENSG00000151657	KIN	100	78.704	ENSODEG00000006713	-	100	73.791	Octodon_degus
ENSG00000151657	KIN	95	83.467	ENSODEG00000004255	-	100	83.467	Octodon_degus
ENSG00000151657	KIN	100	73.935	ENSONIG00000017922	kin	100	73.300	Oreochromis_niloticus
ENSG00000151657	KIN	100	89.567	ENSOANG00000015445	KIN	84	88.295	Ornithorhynchus_anatinus
ENSG00000151657	KIN	99	97.196	ENSOCUG00000004637	KIN	100	96.183	Oryctolagus_cuniculus
ENSG00000151657	KIN	100	75.443	ENSORLG00000017143	kin	100	73.858	Oryzias_latipes
ENSG00000151657	KIN	93	85.366	ENSORLG00020006344	kin	100	74.365	Oryzias_latipes_hni
ENSG00000151657	KIN	100	75.696	ENSORLG00015005954	kin	100	74.112	Oryzias_latipes_hsok
ENSG00000151657	KIN	100	74.177	ENSOMEG00000023512	kin	100	72.843	Oryzias_melastigma
ENSG00000151657	KIN	100	97.222	ENSOGAG00000015236	KIN	99	96.247	Otolemur_garnettii
ENSG00000151657	KIN	99	99.065	ENSOARG00000013813	KIN	100	97.201	Ovis_aries
ENSG00000151657	KIN	100	100.000	ENSPPAG00000035992	KIN	100	100.000	Pan_paniscus
ENSG00000151657	KIN	100	95.165	ENSPPRG00000004708	KIN	100	95.420	Panthera_pardus
ENSG00000151657	KIN	100	95.165	ENSPTIG00000014111	KIN	100	95.420	Panthera_tigris_altaica
ENSG00000151657	KIN	100	100.000	ENSPTRG00000002276	KIN	100	100.000	Pan_troglodytes
ENSG00000151657	KIN	100	98.219	ENSPANG00000023407	KIN	100	98.219	Papio_anubis
ENSG00000151657	KIN	100	76.904	ENSPKIG00000024945	kin	100	75.888	Paramormyrops_kingsleyae
ENSG00000151657	KIN	99	90.654	ENSPSIG00000012871	KIN	99	87.032	Pelodiscus_sinensis
ENSG00000151657	KIN	100	70.483	ENSPMGG00000000617	kin	100	70.992	Periophthalmus_magnuspinnatus
ENSG00000151657	KIN	100	93.893	ENSPEMG00000020236	Kin	100	93.384	Peromyscus_maniculatus_bairdii
ENSG00000151657	KIN	86	92.625	ENSPCIG00000017338	KIN	90	91.740	Phascolarctos_cinereus
ENSG00000151657	KIN	100	71.533	ENSPFOG00000013072	kin	100	70.936	Poecilia_formosa
ENSG00000151657	KIN	100	71.220	ENSPMEG00000005949	kin	100	70.471	Poecilia_mexicana
ENSG00000151657	KIN	100	72.500	ENSPREG00000018077	kin	100	70.781	Poecilia_reticulata
ENSG00000151657	KIN	100	99.491	ENSPPYG00000002075	KIN	100	99.491	Pongo_abelii
ENSG00000151657	KIN	99	99.065	ENSPCAG00000004900	KIN	100	81.934	Procavia_capensis
ENSG00000151657	KIN	97	91.842	ENSPCOG00000016520	-	94	91.053	Propithecus_coquereli
ENSG00000151657	KIN	54	93.925	ENSPCOG00000018039	-	91	93.868	Propithecus_coquereli
ENSG00000151657	KIN	100	95.674	ENSPCOG00000012667	-	100	95.674	Propithecus_coquereli
ENSG00000151657	KIN	99	95.327	ENSPVAG00000006511	KIN	100	94.102	Pteropus_vampyrus
ENSG00000151657	KIN	100	72.544	ENSPNYG00000015699	kin	100	71.033	Pundamilia_nyererei
ENSG00000151657	KIN	100	76.142	ENSPNAG00000008511	kin	100	74.112	Pygocentrus_nattereri
ENSG00000151657	KIN	100	93.639	ENSRNOG00000026690	Kin	100	93.130	Rattus_norvegicus
ENSG00000151657	KIN	100	97.455	ENSRBIG00000044013	-	100	97.455	Rhinopithecus_bieti
ENSG00000151657	KIN	99	90.306	ENSRROG00000026814	-	96	90.051	Rhinopithecus_roxellana
ENSG00000151657	KIN	99	99.065	ENSRROG00000045790	-	100	97.710	Rhinopithecus_roxellana
ENSG00000151657	KIN	100	96.947	ENSRROG00000000512	-	100	96.947	Rhinopithecus_roxellana
ENSG00000151657	KIN	100	96.438	ENSRROG00000024341	-	100	96.438	Rhinopithecus_roxellana
ENSG00000151657	KIN	100	95.674	ENSRROG00000005322	-	100	95.674	Rhinopithecus_roxellana
ENSG00000151657	KIN	100	66.076	ENSRROG00000044061	-	93	92.925	Rhinopithecus_roxellana
ENSG00000151657	KIN	100	98.982	ENSSBOG00000026617	KIN	100	98.982	Saimiri_boliviensis_boliviensis
ENSG00000151657	KIN	84	78.022	ENSSHAG00000001774	-	99	69.310	Sarcophilus_harrisii
ENSG00000151657	KIN	100	92.112	ENSSHAG00000018030	-	100	91.094	Sarcophilus_harrisii
ENSG00000151657	KIN	100	75.573	ENSSFOG00015023995	kin	100	75.064	Scleropages_formosus
ENSG00000151657	KIN	100	72.727	ENSSMAG00000006582	kin	100	70.812	Scophthalmus_maximus
ENSG00000151657	KIN	100	71.788	ENSSDUG00000015489	kin	100	71.537	Seriola_dumerili
ENSG00000151657	KIN	100	71.788	ENSSLDG00000001298	kin	100	70.707	Seriola_lalandi_dorsalis
ENSG00000151657	KIN	99	76.852	ENSSPUG00000001394	KIN	98	75.332	Sphenodon_punctatus
ENSG00000151657	KIN	100	73.552	ENSSPAG00000004783	kin	100	72.911	Stegastes_partitus
ENSG00000151657	KIN	100	72.519	ENSSPAG00000000793	kin	100	72.519	Stegastes_partitus
ENSG00000151657	KIN	100	95.420	ENSSSCG00000033095	KIN	100	95.674	Sus_scrofa
ENSG00000151657	KIN	100	86.768	ENSTGUG00000002119	-	100	85.496	Taeniopygia_guttata
ENSG00000151657	KIN	100	80.407	ENSTGUG00000011716	-	100	79.389	Taeniopygia_guttata
ENSG00000151657	KIN	100	71.788	ENSTRUG00000010720	kin	100	70.558	Takifugu_rubripes
ENSG00000151657	KIN	91	72.727	ENSTNIG00000002346	-	99	68.035	Tetraodon_nigroviridis
ENSG00000151657	KIN	99	99.065	ENSTBEG00000011387	KIN	99	77.863	Tupaia_belangeri
ENSG00000151657	KIN	99	96.262	ENSTTRG00000005048	KIN	100	88.295	Tursiops_truncatus
ENSG00000151657	KIN	100	96.438	ENSUMAG00000012705	KIN	66	96.438	Ursus_maritimus
ENSG00000151657	KIN	99	96.262	ENSVPAG00000007700	KIN	95	93.834	Vicugna_pacos
ENSG00000151657	KIN	99	97.196	ENSVVUG00000006589	-	100	95.929	Vulpes_vulpes
ENSG00000151657	KIN	93	80.000	ENSXETG00000031771	KIN	91	93.182	Xenopus_tropicalis
ENSG00000151657	KIN	100	71.106	ENSXCOG00000011910	kin	100	70.025	Xiphophorus_couchianus
ENSG00000151657	KIN	100	74.750	ENSXMAG00000003029	kin	100	71.033	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003677	DNA binding	1923796.	TAS	Function
GO:0003690	double-stranded DNA binding	21873635.	IBA	Function
GO:0003690	double-stranded DNA binding	-	ISS	Function
GO:0003723	RNA binding	17045609.	IDA	Function
GO:0005515	protein binding	23349634.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0006260	DNA replication	21873635.	IBA	Process
GO:0006260	DNA replication	12359749.	IDA	Process
GO:0006281	DNA repair	-	IEA	Process
GO:0006310	DNA recombination	-	IEA	Process
GO:0006397	mRNA processing	17045609.	TAS	Process
GO:0006974	cellular response to DNA damage stimulus	21873635.	IBA	Process
GO:0006974	cellular response to DNA damage stimulus	12853634.	IEP	Process
GO:0016032	viral process	-	IEA	Process
GO:0016363	nuclear matrix	12754299.	IDA	Component
GO:0032991	protein-containing complex	23349634.	IDA	Component
GO:0043231	intracellular membrane-bounded organelle	-	IDA	Component
GO:0046872	metal ion binding	-	IEA	Function

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.