EuRBPDB

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TCGA tumor abbreviations
  • ACCAdrenocortical carcinoma
  • BLCABladder Urothelial Carcinoma
  • BRCABreast invasive carcinoma
  • CESCCervical squamous cell carcinoma and endocervical adenocarcinoma
  • CHOLCholangio carcinoma
  • COADColon adenocarcinoma
  • DLBCLymphoid Neoplasm Diffuse Large B-cell Lymphoma
  • ESCAEsophageal carcinoma
  • GBMGlioblastoma multiforme
  • HNSCHead and Neck squamous cell carcinoma
  • KICHKidney Chromophobe
  • KIRCKidney renal clear cell carcinoma
  • KIRPKidney renal papillary cell carcinoma
  • LAMLAcute Myeloid Leukemia
  • LGGBrain Lower Grade Glioma
  • LIHCLiver hepatocellular carcinoma
  • LUADLung adenocarcinoma
  • LUSCLung squamous cell carcinoma
  • MESOMesothelioma
  • OVOvarian serous cystadenocarcinoma
  • PAADPancreatic adenocarcinoma
  • PCPGPheochromocytoma and Paraganglioma
  • PRADProstate adenocarcinoma
  • READRectum adenocarcinoma
  • SARCSarcoma
  • SKCMSkin Cutaneous Melanoma
  • STADStomach adenocarcinoma
  • TGCTThyroid carcinoma
  • THCAThyroid carcinoma
  • THYMThymoma
  • UCECUterine Corpus Endometrial Carcinoma
  • UCSUterine Carcinosarcoma
  • UVMUveal Melanoma

Note: Click here to get the extension of tumor abbreviations.


  • Cancer Related Information
  • Basic Information

Cancer associated literatures
PIDTitleArticle TimeAuthorDoi
23188828Phosphorylation of ribosomal protein S3 and antiapoptotic TRAF2 protein mediates radioresistance in non-small cell lung cancer cells.J Biol Chem2013 Feb 1Yang HJdoi: 10.1074/jbc.M112.385989
17140567Human PEP-1-ribosomal protein S3 protects against UV-induced skin cell death.FEBS Lett2006 Dec 22Choi SH-
29048653Ribosomal protein S3 regulates XIAP expression independently of the NF-??B pathway in breast cancer cells.Oncol Rep2017 NovOno Hdoi: 10.3892/or.2017.6008

Expression in 33 cancers

Mutations
CancerChrPosition Mutation TypedbSNPProtein-change Allele FreqRBD
ACCchr1175404171Missense_MutationNAV168I0.89
BLCAchr1175400466Intronnovel0.48
BRCAchr1175400406Intronnovel0.21
BRCAchr1175404171In_Frame_DelnovelD169_V172del0.09
BRCAchr1175404679SilentnovelL182L0.12
CESCchr11753995335'Flanknovel0.55
CESCchr1175400409Intronnovel0.06
CESCchr1175404694Silentrs182461343K187K0.41
CESCchr11754048883'UTRnovel0.3
CHOLchr1175402437Missense_MutationnovelA114V0.11
COADchr1175401690Missense_MutationNAA71D0.22
COADchr1175402424Missense_Mutationrs1802703L110I0.35
COADchr11754049173'UTRnovel0.39
COADchr1175402484Intronnovel0.1
GBMchr1175404043Missense_MutationnovelF125S0.09
GBMchr1175404186Missense_Mutationrs747317928R173C0.36
GBMchr1175400416Intronnovel0.11
HNSCchr1175404126Missense_MutationnovelV153L0.2
KIRCchr1175402412Missense_Mutationrs528039603R106C0.22
KIRCchr1175400780Nonsense_MutationnovelV39_R40ins*0.06
LGGchr1175402395Missense_MutationnovelA100G0.32
LGGchr1175404186Missense_Mutationrs747317928R173C0.55
LIHCchr1175399558Missense_Mutationrs772964979Q4R0.2KH_2
LIHCchr1175404703SilentnovelL190L0.28
LIHCchr1175404128SilentNAV153V0.11
LUADchr1175404753Missense_MutationNAH207R0.39
LUADchr1175404203SilentnovelR178R0.59
LUADchr1175404729Missense_MutationnovelG199A0.21
LUADchr1175400729Missense_MutationNAN22K0.48KH_2
LUADchr1175404208Splice_SitenovelX180_splice0.24
OVchr11754048903'UTRnovel0.38
OVchr1175400782Missense_MutationNAR40Q0.34
READchr1175401673SilentNAR65R0.22
READchr1175400706Missense_MutationNAG15R0.2KH_2
READchr1175404040Missense_MutationNAR124Q0.38
SKCMchr1175404158SilentNAP163P0.46
SKCMchr1175400504Intronnovel0.26
SKCMchr1175404706SilentNAP191P0.11
SKCMchr1175402437Missense_MutationnovelA114D0.68
STADchr1175404178Missense_MutationNAT170I0.16
STADchr1175404422Intronnovel0.23
STADchr1175404725Missense_MutationNAI198V0.23
STADchr1175404504Intronnovel0.64
STADchr11754048863'UTRrs7754654770.17
UCECchr11754049253'UTRnovel0.47
UCECchr1175402701Intronnovel0.22
UCECchr1175404149Silentrs766787196S160S0.26
UCECchr11754049253'UTRnovel0.23
UCECchr1175402448Splice_SitenovelX117_splice0.21
UCECchr1175404036SilentNAL123L0.46
UCECchr1175404198Missense_MutationnovelL177F0.43
UCECchr1175404186Missense_Mutationrs747317928R173C0.46
UCECchr1175400486Intronnovel0.36
UCECchr1175402557Intronnovel0.55
UCECchr1175402411SilentNAL105L0.4
UCECchr1175404754Silentrs560757181H207H0.28
UCECchr1175404457Intronrs7477590020.36
UCECchr1175400722Missense_MutationnovelE20G0.09KH_2
UCECchr1175402577Intronnovel0.44
UCECchr1175404461Intronnovel0.37
UCECchr1175404749Missense_MutationNAD206N0.27
UCECchr1175400752Missense_MutationNAA30D0.26KH_2
UCECchr1175400707Missense_MutationnovelG15D0.32KH_2
UCECchr1175400748Missense_MutationnovelL29M0.43KH_2
UCECchr11754048743'UTRnovel0.67

Copy Number Variations (CNVs)
CancerTypeFreq Q-value
ESCAAMP0.250.018342
TGCTDEL0.69330.21504

Survival Analysis
CancerP-value Q-value
KIRC0.0041

Kaplan-Meier Survival Analysis

SARC0.046

Kaplan-Meier Survival Analysis

ACC0.00011

Kaplan-Meier Survival Analysis

HNSC0.025

Kaplan-Meier Survival Analysis

SKCM0.005

Kaplan-Meier Survival Analysis

KIRP0.0057

Kaplan-Meier Survival Analysis

PAAD0.007

Kaplan-Meier Survival Analysis

GBM0.044

Kaplan-Meier Survival Analysis

LIHC0.029

Kaplan-Meier Survival Analysis

LGG0.00013

Kaplan-Meier Survival Analysis

UVM0.00042

Kaplan-Meier Survival Analysis

Drugs

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Eesembl ID



Cell lines and drugs in GSE70138 or GSE92742

  • Description
  • RBDs
  • RBPome
  • PRI
  • Literatures
  • Expression
  • Transcripts
  • Gene Model
  • Pathways
  • GWAS
  • PPI
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000149273 (Gene tree)
Gene ID
6188
Gene Symbol
RPS3
Alias
FLJ26283|FLJ27450|MGC87870|S3
Full Name
ribosomal protein S3
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Plus strand
Length
22,817 bases
Position
chr11:75,399,486-75,422,302
Accession
10420
RBP type
canonical RBP
Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
RNA binding domains(RBDs)
Protein IDDomain Pfam IDE-value Domain number Total number
ENSP00000433155KH_2PF07650.172.2e-1111
ENSP00000436335KH_2PF07650.175.2e-1111
ENSP00000433821KH_2PF07650.171e-1011
ENSP00000434643KH_2PF07650.171e-1011
ENSP00000436971KH_2PF07650.171e-1011
ENSP00000278572KH_2PF07650.174.5e-1011
ENSP00000433421KH_2PF07650.175e-0911
ENSP00000435457KH_2PF07650.171.3e-0811
ENSP00000433421Ribosomal_S3_CPF00189.201.9e-2211
ENSP00000433821Ribosomal_S3_CPF00189.201.9e-2211
ENSP00000434643Ribosomal_S3_CPF00189.201.9e-2211
ENSP00000436971Ribosomal_S3_CPF00189.201.9e-2211
ENSP00000278572Ribosomal_S3_CPF00189.202.2e-2211
ENSP00000436556Ribosomal_S3_CPF00189.201e-1911
ENSP00000416745Ribosomal_S3_CPF00189.202.3e-1611
ENSP00000435566Ribosomal_S3_CPF00189.203.5e-0811
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
22681889The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts4SURIC & HEK2932012 MayBaltz AGDOI: 10.1016/j.molcel.2012.05.021
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
29431736Capturing the interactome of newly transcribed RNAPolyT-RICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARIC & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
22658674Insights into RNA biology from an atlas of mammalian mRNA-binding proteinsRIC & Hela2012 May 31Castello ADOI: 10.1016/j.cell.2012.04.031
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & MCF72018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & U2OS2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
27453046Comprehensive Identification of RNA-Binding Domains in Human CellsRIC & Hela2016 Aug 18Castello ADOI: 10.1016/j.molcel.2016.06.029
30352994Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome captureRIC & Jurkat2018 Oct 23Perez-Perri JIDOI:10.1038/s41467-018-06557-8
Protein-RNA interaction(RNA-Binding Site)
Click here to download all RNA binding sites
Click here to download all RNA binding sites

Literatures on RNA binding capacity
PIDTitleArticle TimeAuthorDoi
11160884KH domain: one motif, two folds.Nucleic Acids Res2001 Feb 1Grishin NV-
30517713RNA-binding protein RPS3 contributes to hepatocarcinogenesis by post-transcriptionally up-regulating SIRT1.Nucleic Acids Res2019 Feb 28Zhao Ldoi: 10.1093/nar/gky1209.
22773745An essential pentatricopeptide repeat protein facilitates 5' maturation and translation initiation of rps3 mRNA in maize mitochondria.Plant Cell2012 JulManavski Ndoi: 10.1105/tpc.112.099051
29929416MoSnt2-dependent deacetylation of histone H3 mediates MoTor-dependent autophagy and plant infection by the rice blast fungus Magnaporthe oryzae.Autophagy2018He Mdoi: 10.1080/15548627.2018.1458171
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000422465RPS3-202903-ENSP00000416745103 (aa)-E9PSF4
ENST00000534555RPS3-220387--- (aa)--
ENST00000527273RPS3-208390-ENSP00000435457128 (aa)-E9PK82
ENST00000528847RPS3-211639-ENSP0000043556636 (aa)-E9PJN9
ENST00000526608RPS3-207710-ENSP00000433421231 (aa)-E9PL09
ENST00000278572RPS3-201907-ENSP00000278572259 (aa)-P23396
ENST00000525933RPS3-2051307-ENSP00000436556171 (aa)-H0YEU2
ENST00000534440RPS3-219564-ENSP00000436335158 (aa)-E9PPU1
ENST00000529173RPS3-2121373--- (aa)--
ENST00000529285RPS3-213550--- (aa)--
ENST00000527446RPS3-2091306-ENSP00000436971243 (aa)-P23396
ENST00000524851RPS3-203866-ENSP00000433821243 (aa)-P23396
ENST00000528439RPS3-210473-ENSP0000043254291 (aa)-E9PQ96
ENST00000530170RPS3-215531-ENSP00000437105123 (aa)-H0YF32
ENST00000530164RPS3-2141878-ENSP00000433155117 (aa)-F2Z2S8
ENST00000532872RPS3-218737-ENSP00000431834115 (aa)-E9PJH4
ENST00000530721RPS3-216796-ENSP0000043245844 (aa)-E9PQX2
ENST00000525690RPS3-204421-ENSP0000043647633 (aa)-H0YES8
ENST00000531188RPS3-2172097-ENSP00000434643243 (aa)-P23396
ENST00000526248RPS3-206771-ENSP00000431737135 (aa)-H0YCJ7
Gene Model
Click here to download ENSG00000149273's gene model file
Pathways
Pathway IDPathway NameSource
hsa03010RibosomeKEGG
GWAS
ensgIDSNPChromosomePositionSNP-risk TraitPubmedID95% CIOr or BEAT EFO ID
ENSG00000149273rs30181001175417295GMajor depression and alcohol dependence29071344unit increase0.616EFO_0003761|EFO_0003829
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000149273's network

* RBP PPI network refers to all genes directly bind to RBP
Orthologs
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000149273RPS3100100.000ENSAPOG00000001543-78100.000Acanthochromis_polyacanthus
ENSG00000149273RPS3100100.000ENSAPOG00000001551-91100.000Acanthochromis_polyacanthus
ENSG00000149273RPS3100100.000ENSAMEG00000017051RPS39899.588Ailuropoda_melanoleuca
ENSG00000149273RPS310077.778ENSAMEG00000007309-9474.138Ailuropoda_melanoleuca
ENSG00000149273RPS3100100.000ENSACIG00000023535rps310096.735Amphilophus_citrinellus
ENSG00000149273RPS3100100.000ENSAOCG00000013654rps310096.327Amphiprion_ocellaris
ENSG00000149273RPS3100100.000ENSAPEG00000022808rps310096.327Amphiprion_percula
ENSG00000149273RPS3100100.000ENSATEG00000003502rps310095.510Anabas_testudineus
ENSG00000149273RPS310099.145ENSAPLG00000014513-10076.923Anas_platyrhynchos
ENSG00000149273RPS3100100.000ENSACAG00000002169-10097.942Anolis_carolinensis
ENSG00000149273RPS39981.897ENSANAG00000022561-10081.897Aotus_nancymaae
ENSG00000149273RPS39898.876ENSANAG00000019985-10087.255Aotus_nancymaae
ENSG00000149273RPS310095.385ENSANAG00000023438-100100.000Aotus_nancymaae
ENSG00000149273RPS3100100.000ENSANAG00000027669-100100.000Aotus_nancymaae
ENSG00000149273RPS3100100.000ENSACLG00000013763rps39491.102Astatotilapia_calliptera
ENSG00000149273RPS3100100.000ENSAMXG00000013642rps310096.327Astyanax_mexicanus
ENSG00000149273RPS3100100.000ENSBTAG00000005620RPS3100100.000Bos_taurus
ENSG00000149273RPS39183.333ENSBTAG00000051928-9976.190Bos_taurus
ENSG00000149273RPS39788.571WBGene00004472rps-39674.684Caenorhabditis_elegans
ENSG00000149273RPS310090.323ENSCJAG00000041948-10090.323Callithrix_jacchus
ENSG00000149273RPS3100100.000ENSCJAG00000015424RPS3100100.000Callithrix_jacchus
ENSG00000149273RPS3100100.000ENSCAFG00000005402RPS310099.588Canis_familiaris
ENSG00000149273RPS3100100.000ENSCAFG00020002102-10099.588Canis_lupus_dingo
ENSG00000149273RPS39180.000ENSCHIG00000015952-8764.455Capra_hircus
ENSG00000149273RPS3100100.000ENSCHIG00000012342-100100.000Capra_hircus
ENSG00000149273RPS3100100.000ENSTSYG00000008664-100100.000Carlito_syrichta
ENSG00000149273RPS310094.872ENSTSYG00000034881-9695.489Carlito_syrichta
ENSG00000149273RPS3100100.000ENSCAPG00000016681-9799.571Cavia_aperea
ENSG00000149273RPS3100100.000ENSCPOG00000004665-10099.588Cavia_porcellus
ENSG00000149273RPS3100100.000ENSCCAG00000022155RPS3100100.000Cebus_capucinus
ENSG00000149273RPS310097.222ENSCCAG00000021048-10087.500Cebus_capucinus
ENSG00000149273RPS310094.444ENSCATG00000043998-10089.362Cercocebus_atys
ENSG00000149273RPS3100100.000ENSCATG00000035348-100100.000Cercocebus_atys
ENSG00000149273RPS310092.308ENSCATG00000037875-10093.750Cercocebus_atys
ENSG00000149273RPS39190.000ENSCATG00000011713-10094.444Cercocebus_atys
ENSG00000149273RPS3100100.000ENSCLAG00000013819-10099.588Chinchilla_lanigera
ENSG00000149273RPS3100100.000ENSCSAG00000003937-100100.000Chlorocebus_sabaeus
ENSG00000149273RPS310098.291ENSCHOG00000005328-10081.070Choloepus_hoffmanni
ENSG00000149273RPS3100100.000ENSCPBG00000027671-8898.421Chrysemys_picta_bellii
ENSG00000149273RPS310094.444ENSCPBG00000023316-8888.034Chrysemys_picta_bellii
ENSG00000149273RPS310097.222ENSCING00000005003-9185.185Ciona_intestinalis
ENSG00000149273RPS310097.222ENSCSAVG00000003490-9285.654Ciona_savignyi
ENSG00000149273RPS3100100.000ENSCANG00000041522-10082.251Colobus_angolensis_palliatus
ENSG00000149273RPS3100100.000ENSCANG00000036026RPS3100100.000Colobus_angolensis_palliatus
ENSG00000149273RPS3100100.000ENSCGRG00001013667Rps395100.000Cricetulus_griseus_chok1gshd
ENSG00000149273RPS310088.350ENSCGRG00001003744-9976.856Cricetulus_griseus_chok1gshd
ENSG00000149273RPS3100100.000ENSCGRG00000004739-9796.281Cricetulus_griseus_crigri
ENSG00000149273RPS39889.565ENSCGRG00000000152-9481.498Cricetulus_griseus_crigri
ENSG00000149273RPS310088.350ENSCGRG00000004849-9976.856Cricetulus_griseus_crigri
ENSG00000149273RPS3100100.000ENSCGRG00000019934-10093.827Cricetulus_griseus_crigri
ENSG00000149273RPS3100100.000ENSCSEG00000014436rps310095.918Cynoglossus_semilaevis
ENSG00000149273RPS3100100.000ENSCVAG00000009247rps310095.918Cyprinodon_variegatus
ENSG00000149273RPS3100100.000ENSDARG00000103007rps310095.918Danio_rerio
ENSG00000149273RPS310088.889ENSDNOG00000032230-9882.716Dasypus_novemcinctus
ENSG00000149273RPS39785.714ENSDNOG00000014888-9678.151Dasypus_novemcinctus
ENSG00000149273RPS3100100.000ENSDNOG00000037189-9896.970Dasypus_novemcinctus
ENSG00000149273RPS310077.778ENSDNOG00000038002-8877.778Dasypus_novemcinctus
ENSG00000149273RPS3100100.000ENSDORG00000002974Rps310099.588Dipodomys_ordii
ENSG00000149273RPS310083.761ENSDORG00000025518-9884.483Dipodomys_ordii
ENSG00000149273RPS3100100.000FBgn0002622RpS39383.913Drosophila_melanogaster
ENSG00000149273RPS3100100.000ENSETEG00000015500-10082.716Echinops_telfairi
ENSG00000149273RPS39193.333ENSEBUG00000003683rps38586.076Eptatretus_burgeri
ENSG00000149273RPS3100100.000ENSEASG00005014248-8699.588Equus_asinus_asinus
ENSG00000149273RPS3100100.000ENSECAG00000013915-8699.588Equus_caballus
ENSG00000149273RPS3100100.000ENSEEUG00000014531-10097.531Erinaceus_europaeus
ENSG00000149273RPS310099.145ENSELUG00000017575-10094.286Esox_lucius
ENSG00000149273RPS3100100.000ENSELUG00000024369-9995.918Esox_lucius
ENSG00000149273RPS39776.991ENSFCAG00000029480-9776.991Felis_catus
ENSG00000149273RPS310086.111ENSFCAG00000033114-9469.277Felis_catus
ENSG00000149273RPS3100100.000ENSFCAG00000011942-10099.588Felis_catus
ENSG00000149273RPS3100100.000ENSFALG00000007956-7698.765Ficedula_albicollis
ENSG00000149273RPS3100100.000ENSFDAG00000016319-10099.588Fukomys_damarensis
ENSG00000149273RPS310074.725ENSFDAG00000012411-10075.385Fukomys_damarensis
ENSG00000149273RPS3100100.000ENSFHEG00000022153rps310094.694Fundulus_heteroclitus
ENSG00000149273RPS3100100.000ENSGMOG00000000838rps310095.528Gadus_morhua
ENSG00000149273RPS3100100.000ENSGALG00000017330-10098.765Gallus_gallus
ENSG00000149273RPS3100100.000ENSGAFG00000015709rps310095.918Gambusia_affinis
ENSG00000149273RPS3100100.000ENSGACG00000013384rps310095.918Gasterosteus_aculeatus
ENSG00000149273RPS310094.444ENSGAGG00000022297-9270.186Gopherus_agassizii
ENSG00000149273RPS3100100.000ENSGAGG00000012704-10098.765Gopherus_agassizii
ENSG00000149273RPS39997.727ENSGGOG00000026674-9793.416Gorilla_gorilla
ENSG00000149273RPS39397.647ENSGGOG00000037758-7894.505Gorilla_gorilla
ENSG00000149273RPS310087.379ENSGGOG00000022405-8598.276Gorilla_gorilla
ENSG00000149273RPS310096.923ENSGGOG00000038504-8898.462Gorilla_gorilla
ENSG00000149273RPS310077.670ENSGGOG00000041474-9477.670Gorilla_gorilla
ENSG00000149273RPS3100100.000ENSGGOG00000006519RPS3100100.000Gorilla_gorilla
ENSG00000149273RPS3100100.000ENSHBUG00000002368rps310095.918Haplochromis_burtoni
ENSG00000149273RPS3100100.000ENSHGLG00000019339RPS310099.177Heterocephalus_glaber_female
ENSG00000149273RPS39193.333ENSHGLG00000015886-10078.431Heterocephalus_glaber_female
ENSG00000149273RPS3100100.000ENSHGLG00100012857RPS310099.177Heterocephalus_glaber_male
ENSG00000149273RPS310097.222ENSHGLG00100017077-10093.162Heterocephalus_glaber_male
ENSG00000149273RPS3100100.000ENSHCOG00000005060rps39695.359Hippocampus_comes
ENSG00000149273RPS3100100.000ENSIPUG00000005685rps310096.327Ictalurus_punctatus
ENSG00000149273RPS3100100.000ENSSTOG00000028813-10099.588Ictidomys_tridecemlineatus
ENSG00000149273RPS3100100.000ENSJJAG00000017023-9698.857Jaculus_jaculus
ENSG00000149273RPS3100100.000ENSJJAG00000018981Rps310099.588Jaculus_jaculus
ENSG00000149273RPS3100100.000ENSKMAG00000009747rps310096.327Kryptolebias_marmoratus
ENSG00000149273RPS3100100.000ENSLBEG00000021017rps310096.327Labrus_bergylta
ENSG00000149273RPS3100100.000ENSLACG00000006132-10097.531Latimeria_chalumnae
ENSG00000149273RPS3100100.000ENSLOCG00000006405rps39996.296Lepisosteus_oculatus
ENSG00000149273RPS3100100.000ENSLAFG00000004297-10099.588Loxodonta_africana
ENSG00000149273RPS3100100.000ENSMFAG00000000525RPS3100100.000Macaca_fascicularis
ENSG00000149273RPS3100100.000ENSMMUG00000009019RPS3100100.000Macaca_mulatta
ENSG00000149273RPS310094.444ENSMMUG00000045640-10078.189Macaca_mulatta
ENSG00000149273RPS310094.444ENSMMUG00000037851-8975.728Macaca_mulatta
ENSG00000149273RPS310091.667ENSMNEG00000030799-10077.489Macaca_nemestrina
ENSG00000149273RPS3100100.000ENSMNEG00000032069-100100.000Macaca_nemestrina
ENSG00000149273RPS310089.231ENSMLEG00000032606-10090.625Mandrillus_leucophaeus
ENSG00000149273RPS310094.444ENSMLEG00000017301-10080.519Mandrillus_leucophaeus
ENSG00000149273RPS3100100.000ENSMLEG00000027047RPS3100100.000Mandrillus_leucophaeus
ENSG00000149273RPS310097.222ENSMLEG00000044314-10092.208Mandrillus_leucophaeus
ENSG00000149273RPS3100100.000ENSMAMG00000020146rps310096.327Mastacembelus_armatus
ENSG00000149273RPS3100100.000ENSMZEG00005024678rps310087.983Maylandia_zebra
ENSG00000149273RPS3100100.000ENSMGAG00000016912-100100.000Meleagris_gallopavo
ENSG00000149273RPS3100100.000ENSMAUG00000012031-10099.588Mesocricetus_auratus
ENSG00000149273RPS310080.556ENSMAUG00000015088-10072.840Mesocricetus_auratus
ENSG00000149273RPS310098.291ENSMAUG00000006329-10093.004Mesocricetus_auratus
ENSG00000149273RPS310094.444ENSMICG00000033427-10084.120Microcebus_murinus
ENSG00000149273RPS3100100.000ENSMICG00000030910-100100.000Microcebus_murinus
ENSG00000149273RPS3100100.000ENSMOCG00000007699Rps310099.588Microtus_ochrogaster
ENSG00000149273RPS3100100.000ENSMMOG00000005152rps310094.694Mola_mola
ENSG00000149273RPS3100100.000ENSMODG00000006945-10099.177Monodelphis_domestica
ENSG00000149273RPS3100100.000ENSMALG00000021156rps310095.902Monopterus_albus
ENSG00000149273RPS3100100.000MGP_CAROLIEiJ_G0030029Rps310099.588Mus_caroli
ENSG00000149273RPS3100100.000ENSMUSG00000030744Rps310099.588Mus_musculus
ENSG00000149273RPS3100100.000MGP_PahariEiJ_G0013250Rps310099.588Mus_pahari
ENSG00000149273RPS3100100.000MGP_SPRETEiJ_G0031139Rps310099.588Mus_spretus
ENSG00000149273RPS3100100.000ENSMPUG00000009197-10099.588Mustela_putorius_furo
ENSG00000149273RPS310080.556ENSMLUG00000026956-9775.641Myotis_lucifugus
ENSG00000149273RPS3100100.000ENSMLUG00000004079-10099.177Myotis_lucifugus
ENSG00000149273RPS39881.538ENSMLUG00000025123-10072.614Myotis_lucifugus
ENSG00000149273RPS3100100.000ENSNGAG00000015514Rps310099.588Nannospalax_galili
ENSG00000149273RPS3100100.000ENSNBRG00000006241rps310096.327Neolamprologus_brichardi
ENSG00000149273RPS38984.615ENSNLEG00000029322-9886.331Nomascus_leucogenys
ENSG00000149273RPS310095.385ENSNLEG00000027260-10086.325Nomascus_leucogenys
ENSG00000149273RPS3100100.000ENSNLEG00000036221-100100.000Nomascus_leucogenys
ENSG00000149273RPS3100100.000ENSMEUG00000011581-10098.354Notamacropus_eugenii
ENSG00000149273RPS310098.413ENSOPRG00000009496-73100.000Ochotona_princeps
ENSG00000149273RPS310095.652ENSODEG00000006804-10096.875Octodon_degus
ENSG00000149273RPS39198.795ENSODEG00000013117-7098.795Octodon_degus
ENSG00000149273RPS310084.615ENSODEG00000003742-9884.746Octodon_degus
ENSG00000149273RPS39193.333ENSODEG00000001789-9784.868Octodon_degus
ENSG00000149273RPS39894.059ENSODEG00000000640-10087.654Octodon_degus
ENSG00000149273RPS3100100.000ENSODEG00000004564-10099.177Octodon_degus
ENSG00000149273RPS39695.402ENSODEG00000004737-9595.402Octodon_degus
ENSG00000149273RPS310094.017ENSODEG00000002537-10088.477Octodon_degus
ENSG00000149273RPS3100100.000ENSONIG00000001263rps38896.735Oreochromis_niloticus
ENSG00000149273RPS310080.556ENSOANG00000009953-10072.986Ornithorhynchus_anatinus
ENSG00000149273RPS39896.629ENSOANG00000029410-7881.982Ornithorhynchus_anatinus
ENSG00000149273RPS399100.000ENSOCUG00000024686-9894.538Oryctolagus_cuniculus
ENSG00000149273RPS3100100.000ENSOCUG00000022412-8699.588Oryctolagus_cuniculus
ENSG00000149273RPS3100100.000ENSORLG00000000607rps310095.918Oryzias_latipes
ENSG00000149273RPS3100100.000ENSORLG00020021035rps39995.902Oryzias_latipes_hni
ENSG00000149273RPS3100100.000ENSORLG00015010080rps310095.918Oryzias_latipes_hsok
ENSG00000149273RPS371100.000ENSOMEG00000013827-9579.348Oryzias_melastigma
ENSG00000149273RPS3100100.000ENSOMEG00000020705rps39093.827Oryzias_melastigma
ENSG00000149273RPS3100100.000ENSOGAG00000005318RPS310099.590Otolemur_garnettii
ENSG00000149273RPS3100100.000ENSOARG00000011523RPS386100.000Ovis_aries
ENSG00000149273RPS310076.699ENSPPAG00000031469-9476.699Pan_paniscus
ENSG00000149273RPS3100100.000ENSPPAG00000029211RPS3100100.000Pan_paniscus
ENSG00000149273RPS39795.000ENSPPAG00000039573-8988.608Pan_paniscus
ENSG00000149273RPS310092.308ENSPPAG00000033710-9092.444Pan_paniscus
ENSG00000149273RPS3100100.000ENSPPRG00000021200-10099.588Panthera_pardus
ENSG00000149273RPS39378.824ENSPPRG00000000760-6677.570Panthera_pardus
ENSG00000149273RPS3100100.000ENSPTIG00000012777-10099.588Panthera_tigris_altaica
ENSG00000149273RPS310094.444ENSPTRG00000015680-9192.593Pan_troglodytes
ENSG00000149273RPS3100100.000ENSPTRG00000048574RPS3100100.000Pan_troglodytes
ENSG00000149273RPS310076.699ENSPTRG00000048315-9476.699Pan_troglodytes
ENSG00000149273RPS39696.610ENSPTRG00000047374-8986.842Pan_troglodytes
ENSG00000149273RPS310087.379ENSPANG00000033652-9992.188Papio_anubis
ENSG00000149273RPS310078.659ENSPANG00000032441-10093.478Papio_anubis
ENSG00000149273RPS3100100.000ENSPANG00000016549-100100.000Papio_anubis
ENSG00000149273RPS3100100.000ENSPKIG00000024046rps310095.918Paramormyrops_kingsleyae
ENSG00000149273RPS3100100.000ENSPSIG00000008818-10098.765Pelodiscus_sinensis
ENSG00000149273RPS3100100.000ENSPMGG00000012744rps310096.311Periophthalmus_magnuspinnatus
ENSG00000149273RPS310072.308ENSPEMG00000022426-10070.782Peromyscus_maniculatus_bairdii
ENSG00000149273RPS3100100.000ENSPEMG00000021741-10099.588Peromyscus_maniculatus_bairdii
ENSG00000149273RPS310087.692ENSPEMG00000020704-10082.787Peromyscus_maniculatus_bairdii
ENSG00000149273RPS3100100.000ENSPMAG00000007775-9693.750Petromyzon_marinus
ENSG00000149273RPS382100.000ENSPCIG00000026362-9082.796Phascolarctos_cinereus
ENSG00000149273RPS310091.667ENSPCIG00000018997-8687.179Phascolarctos_cinereus
ENSG00000149273RPS3100100.000ENSPCIG00000024144-10098.354Phascolarctos_cinereus
ENSG00000149273RPS310094.444ENSPCIG00000030274-8885.556Phascolarctos_cinereus
ENSG00000149273RPS39790.909ENSPCIG00000022539-10094.253Phascolarctos_cinereus
ENSG00000149273RPS3100100.000ENSPFOG00000013835rps310095.918Poecilia_formosa
ENSG00000149273RPS3100100.000ENSPLAG00000005854rps310095.918Poecilia_latipinna
ENSG00000149273RPS3100100.000ENSPMEG00000020999rps310095.918Poecilia_mexicana
ENSG00000149273RPS3100100.000ENSPREG00000017536rps310095.918Poecilia_reticulata
ENSG00000149273RPS3100100.000ENSPPYG00000003688RPS3100100.000Pongo_abelii
ENSG00000149273RPS3100100.000ENSPCAG00000003033-10081.070Procavia_capensis
ENSG00000149273RPS39988.793ENSPCOG00000026192-10091.379Propithecus_coquereli
ENSG00000149273RPS310094.624ENSPCOG00000021977-10094.624Propithecus_coquereli
ENSG00000149273RPS3100100.000ENSPCOG00000028750RPS3100100.000Propithecus_coquereli
ENSG00000149273RPS39984.615ENSPCOG00000024652-10075.983Propithecus_coquereli
ENSG00000149273RPS3100100.000ENSPVAG00000011271-10093.827Pteropus_vampyrus
ENSG00000149273RPS3100100.000ENSPNYG00000007419rps310096.327Pundamilia_nyererei
ENSG00000149273RPS39768.182ENSPNYG00000007471-10068.182Pundamilia_nyererei
ENSG00000149273RPS3100100.000ENSPNAG00000018641rps310096.327Pygocentrus_nattereri
ENSG00000149273RPS3100100.000ENSRNOG00000017418Rps310099.588Rattus_norvegicus
ENSG00000149273RPS310097.087ENSRNOG00000007605AABR07052430.110095.885Rattus_norvegicus
ENSG00000149273RPS38483.582ENSRNOG00000056660AABR07025928.110085.507Rattus_norvegicus
ENSG00000149273RPS39494.118ENSRBIG00000012001-10073.936Rhinopithecus_bieti
ENSG00000149273RPS3100100.000ENSRBIG00000044916RPS3100100.000Rhinopithecus_bieti
ENSG00000149273RPS310094.444ENSRBIG00000040846-10087.243Rhinopithecus_bieti
ENSG00000149273RPS310099.145ENSRBIG00000042266-10093.407Rhinopithecus_bieti
ENSG00000149273RPS310092.308ENSRBIG00000033623-10093.750Rhinopithecus_bieti
ENSG00000149273RPS310099.145ENSRROG00000039976-9397.744Rhinopithecus_roxellana
ENSG00000149273RPS310094.444ENSRROG00000039887-10094.872Rhinopithecus_roxellana
ENSG00000149273RPS3100100.000ENSRROG00000032977-10095.726Rhinopithecus_roxellana
ENSG00000149273RPS38589.630ENSRROG00000037141-10093.750Rhinopithecus_roxellana
ENSG00000149273RPS3100100.000ENSRROG00000009870RPS3100100.000Rhinopithecus_roxellana
ENSG00000149273RPS39782.857YNL178WRPS39965.975Saccharomyces_cerevisiae
ENSG00000149273RPS3100100.000ENSSBOG00000021847-100100.000Saimiri_boliviensis_boliviensis
ENSG00000149273RPS310094.175ENSSBOG00000021803-8993.750Saimiri_boliviensis_boliviensis
ENSG00000149273RPS310091.667ENSSBOG00000024651-8675.210Saimiri_boliviensis_boliviensis
ENSG00000149273RPS3100100.000ENSSHAG00000011198-9996.667Sarcophilus_harrisii
ENSG00000149273RPS3100100.000ENSSFOG00015002290rps310095.918Scleropages_formosus
ENSG00000149273RPS3100100.000ENSSMAG00000004341rps310095.528Scophthalmus_maximus
ENSG00000149273RPS3100100.000ENSSDUG00000004327rps310095.918Seriola_dumerili
ENSG00000149273RPS3100100.000ENSSLDG00000018053rps310095.918Seriola_lalandi_dorsalis
ENSG00000149273RPS310085.470ENSSLDG00000007403-9985.714Seriola_lalandi_dorsalis
ENSG00000149273RPS3100100.000ENSSARG00000006979-9897.046Sorex_araneus
ENSG00000149273RPS3100100.000ENSSPUG00000017181-10097.854Sphenodon_punctatus
ENSG00000149273RPS3100100.000ENSSPAG00000022245rps310096.735Stegastes_partitus
ENSG00000149273RPS310088.889ENSSSCG00000036413-9862.719Sus_scrofa
ENSG00000149273RPS3100100.000ENSSSCG00000014855RPS3100100.000Sus_scrofa
ENSG00000149273RPS3100100.000ENSTGUG00000013480-9997.368Taeniopygia_guttata
ENSG00000149273RPS39398.824ENSTGUG00000016614-9998.824Taeniopygia_guttata
ENSG00000149273RPS3100100.000ENSTRUG00000023549rps310097.143Takifugu_rubripes
ENSG00000149273RPS39398.824ENSTNIG00000006029rps35584.762Tetraodon_nigroviridis
ENSG00000149273RPS3100100.000ENSTBEG00000007053-10099.588Tupaia_belangeri
ENSG00000149273RPS3100100.000ENSTTRG00000005858RPS3100100.000Tursiops_truncatus
ENSG00000149273RPS310079.348ENSUAMG00000007373-10079.348Ursus_americanus
ENSG00000149273RPS3100100.000ENSUAMG00000021546-10099.588Ursus_americanus
ENSG00000149273RPS3100100.000ENSUMAG00000010808-10099.588Ursus_maritimus
ENSG00000149273RPS3100100.000ENSVPAG00000011615RPS3100100.000Vicugna_pacos
ENSG00000149273RPS39676.974ENSVVUG00000018431-10077.778Vulpes_vulpes
ENSG00000149273RPS3100100.000ENSVVUG00000024353-10099.588Vulpes_vulpes
ENSG00000149273RPS3100100.000ENSXETG00000010729rps310096.761Xenopus_tropicalis
ENSG00000149273RPS3100100.000ENSXCOG00000012468rps310095.918Xiphophorus_couchianus
ENSG00000149273RPS3100100.000ENSXMAG00000004703rps310095.918Xiphophorus_maculatus
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-TASProcess
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding18045535.IMPFunction
GO:0003677DNA binding18610840.IDAFunction
GO:0003684damaged DNA binding21873635.IBAFunction
GO:0003684damaged DNA binding14706345.16737853.17560175.18610840.IDAFunction
GO:0003723RNA binding22658674.22681889.HDAFunction
GO:0003723RNA binding20217897.IDAFunction
GO:0003729mRNA binding18464793.IDAFunction
GO:0003735structural constituent of ribosome15883184.HDAFunction
GO:0003735structural constituent of ribosome21873635.IBAFunction
GO:0003735structural constituent of ribosome1712897.NASFunction
GO:0003906DNA-(apurinic or apyrimidinic site) endonuclease activity21873635.IBAFunction
GO:0003906DNA-(apurinic or apyrimidinic site) endonuclease activity7775413.15707971.16737853.18610840.19059439.IDAFunction
GO:0004520endodeoxyribonuclease activity15707971.20605787.IDAFunction
GO:0005515protein binding15161933.18045535.18274552.19656744.20041225.20618440.21146485.21399639.22244329.22510408.23911537.24423872.24457201.24725412.24965446.25609649.26526615.28065601.28132843.IPIFunction
GO:0005634nucleus21873635.IBAComponent
GO:0005634nucleus14988002.16814409.17560175.18045535.19059439.19460357.20041225.IDAComponent
GO:0005634nucleus21399639.21871177.IMPComponent
GO:0005654nucleoplasm-TASComponent
GO:0005730nucleolus19460357.IDAComponent
GO:0005737cytoplasm14988002.19059439.20217897.IDAComponent
GO:0005737cytoplasm21871177.IMPComponent
GO:0005743mitochondrial inner membrane23911537.IDAComponent
GO:0005759mitochondrial matrix23911537.IDAComponent
GO:0005783endoplasmic reticulum-IDAComponent
GO:0005829cytosol16814409.17560175.18045535.IDAComponent
GO:0005829cytosol-TASComponent
GO:0005840ribosome19059439.19460357.20217897.IDAComponent
GO:0005844polysome19460357.IDAComponent
GO:0005886plasma membrane22510408.IDAComponent
GO:0005925focal adhesion21423176.HDAComponent
GO:0006281DNA repair21873635.IBAProcess
GO:0006412translation8706699.ICProcess
GO:0006412translation1712897.NASProcess
GO:0006413translational initiation15883184.NASProcess
GO:0006413translational initiation-TASProcess
GO:0006614SRP-dependent cotranslational protein targeting to membrane-TASProcess
GO:0006915apoptotic process-IEAProcess
GO:0006974cellular response to DNA damage stimulus17560175.IEPProcess
GO:0006979response to oxidative stress23911537.IDAProcess
GO:0007059chromosome segregation23131551.IMPProcess
GO:0008017microtubule binding23131551.IDAFunction
GO:0008134transcription factor binding20605787.IPIFunction
GO:0008534oxidized purine nucleobase lesion DNA N-glycosylase activity21873635.IBAFunction
GO:0010628positive regulation of gene expression20605787.IMPProcess
GO:0014069postsynaptic density21170055.EXPComponent
GO:0014069postsynaptic density21170055.IDAComponent
GO:0015631tubulin binding23131551.IDAFunction
GO:0016020membrane19946888.HDAComponent
GO:0017148negative regulation of translation20217897.IDAProcess
GO:0019083viral transcription-TASProcess
GO:0019104DNA N-glycosylase activity18610840.IDAFunction
GO:0019104DNA N-glycosylase activity15707971.TASFunction
GO:0019899enzyme binding15518571.18973764.19460357.IPIFunction
GO:0019900kinase binding19059439.20605787.IPIFunction
GO:0019901protein kinase binding15950189.21871177.IPIFunction
GO:0022627cytosolic small ribosomal subunit15883184.HDAComponent
GO:0022627cytosolic small ribosomal subunit21873635.IBAComponent
GO:0022627cytosolic small ribosomal subunit8706699.IDAComponent
GO:0030544Hsp70 protein binding23911537.IDAFunction
GO:0031116positive regulation of microtubule polymerization23131551.IMPProcess
GO:0031334positive regulation of protein complex assembly18045535.IMPProcess
GO:0031397negative regulation of protein ubiquitination19656744.IDAProcess
GO:0032079positive regulation of endodeoxyribonuclease activity18973764.IDAProcess
GO:0032357oxidized purine DNA binding21873635.IBAFunction
GO:0032357oxidized purine DNA binding14706345.IDAFunction
GO:0032358oxidized pyrimidine DNA binding19656744.IDAFunction
GO:0032587ruffle membrane16814409.IDAComponent
GO:0032743positive regulation of interleukin-2 production18045535.IMPProcess
GO:0042104positive regulation of activated T cell proliferation18045535.IMPProcess
GO:0042769DNA damage response, detection of DNA damage23911537.IDAProcess
GO:0042769DNA damage response, detection of DNA damage22510408.IMPProcess
GO:0042981regulation of apoptotic process20605787.IMPProcess
GO:0043507positive regulation of JUN kinase activity22510408.IMPProcess
GO:0044390ubiquitin-like protein conjugating enzyme binding21968017.IPIFunction
GO:0044877protein-containing complex binding18045535.IMPFunction
GO:0045738negative regulation of DNA repair17049931.IMPProcess
GO:0045739positive regulation of DNA repair21873635.IBAProcess
GO:0045739positive regulation of DNA repair23911537.IDAProcess
GO:0050862positive regulation of T cell receptor signaling pathway18045535.IMPProcess
GO:0051018protein kinase A binding16814409.IPIFunction
GO:0051092positive regulation of NF-kappaB transcription factor activity18045535.IGIProcess
GO:0051092positive regulation of NF-kappaB transcription factor activity18045535.IMPProcess
GO:0051225spindle assembly23131551.IMPProcess
GO:0051301cell division-IEAProcess
GO:0051536iron-sulfur cluster binding11911468.NASFunction
GO:0051879Hsp90 protein binding23911537.IDAFunction
GO:0061481response to TNF agonist20041225.IDAProcess
GO:0070062extracellular exosome20458337.HDAComponent
GO:0070181small ribosomal subunit rRNA binding18610840.IDAFunction
GO:0070301cellular response to hydrogen peroxide23911537.IDAProcess
GO:0071159NF-kappaB complex18045535.IDAComponent
GO:0071356cellular response to tumor necrosis factor18045535.IMPProcess
GO:0072686mitotic spindle23131551.IDAComponent
GO:0097100supercoiled DNA binding15707971.IDAFunction
GO:0140078class I DNA-(apurinic or apyrimidinic site) endonuclease activity-IEAFunction
GO:1901224positive regulation of NIK/NF-kappaB signaling20041225.IDAProcess
GO:1902231positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage22510408.IMPProcess
GO:1902546positive regulation of DNA N-glycosylase activity15518571.IDAProcess
GO:1905053positive regulation of base-excision repair18973764.IDAProcess
GO:1990904ribonucleoprotein complex17289661.IDAComponent
GO:2001235positive regulation of apoptotic signaling pathway21873635.IBAProcess
GO:2001235positive regulation of apoptotic signaling pathway14988002.IDAProcess
GO:2001272positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis22510408.IMPProcess
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