EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
17341490	PGC-1alpha/beta upregulation is associated with improved oxidative phosphorylation in cells harboring nonsense mtDNA mutations.	Hum Mol Genet	2007 Apr 15	Srivastava S	-

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr10	102141509	Missense_Mutation	novel	P1001A	0.11
ACC	chr10	102140252	Missense_Mutation	novel	A582T	0.4
BLCA	chr10	102147341	Missense_Mutation	NA	S1450L	0.62
BLCA	chr10	102147236	Missense_Mutation	NA	S1415L	0.68
BLCA	chr10	102149946	Missense_Mutation	novel	D1638N	0.22
BLCA	chr10	102139546	Silent	novel	L346L	0.24
BLCA	chr10	102139547	Missense_Mutation	rs753734181	E347K	0.24
BLCA	chr10	102138731	Missense_Mutation	novel	S152L	0.19
BLCA	chr10	102137896	Missense_Mutation	NA	S67F	0.47
BLCA	chr10	102141030	Missense_Mutation	NA	S841L	0.4
BLCA	chr10	102141055	Silent	novel	S849S	0.05
BLCA	chr10	102146951	Missense_Mutation	NA	R1320P	0.2
BLCA	chr10	102148669	Missense_Mutation	NA	R1531T	0.27
BLCA	chr10	102149310	Missense_Mutation	NA	K1624N	0.27
BLCA	chr10	102139614	Missense_Mutation	novel	S369C	0.19
BLCA	chr10	102140420	Missense_Mutation	NA	D638N	0.21
BLCA	chr10	102140707	Silent	NA	L733L	0.26
BLCA	chr10	102141655	Silent	NA	Q1049Q	0.14
BLCA	chr10	102139604	Nonsense_Mutation	novel	R366*	0.14
BLCA	chr10	102138939	Missense_Mutation	NA	D184N	0.54
BLCA	chr10	102139703	Missense_Mutation	NA	E399Q	0.48
BLCA	chr10	102139273	Silent	novel	F255F	0.29
BLCA	chr10	102139941	Missense_Mutation	novel	R478M	0.08
BLCA	chr10	102139146	Missense_Mutation	rs746664279	S213C	0.11
BLCA	chr10	102149294	Missense_Mutation	NA	R1619Q	0.13
BRCA	chr10	102146861	Missense_Mutation	NA	H1290R	0.57
BRCA	chr10	102148642	Missense_Mutation	novel	R1522H	0.04
BRCA	chr10	102148693	Missense_Mutation	novel	I1539T	0.09
BRCA	chr10	102145059	Silent	novel	R1216R	0.09
BRCA	chr10	102147376	Missense_Mutation	rs780258251	H1462Y	0.1
BRCA	chr10	102146971	Nonsense_Mutation	novel	Q1327*	0.19
BRCA	chr10	102145024	Missense_Mutation	rs757322330	V1205I	0.24
BRCA	chr10	102137914	Missense_Mutation	NA	L73Q	0.41
BRCA	chr10	102139338	Missense_Mutation	NA	H277P	0.19
BRCA	chr10	102149958	Missense_Mutation	NA	V1642I	0.35
BRCA	chr10	102140166	Missense_Mutation	novel	G553V	0.39
BRCA	chr10	102148645	Missense_Mutation	NA	S1523L	0.34
CESC	chr10	102147368	Missense_Mutation	NA	S1459Y	0.26
CESC	chr10	102148535	Intron	rs776761013		0.39
CESC	chr10	102150101	3'UTR	novel		0.4
CESC	chr10	102141788	Missense_Mutation	novel	E1094Q	0.29
CESC	chr10	102141886	Missense_Mutation	NA	Q1126H	0.17
COAD	chr10	102140264	Missense_Mutation	NA	P586S	0.36
COAD	chr10	102138654	Silent	NA	S126S	0.36
COAD	chr10	102140796	Missense_Mutation	rs777850442	R763H	0.27
COAD	chr10	102139236	Missense_Mutation	NA	R243H	0.23
COAD	chr10	102140933	Missense_Mutation	NA	R809G	0.16
COAD	chr10	102137889	Missense_Mutation	novel	S65G	0.25
COAD	chr10	102140639	Missense_Mutation	rs17847386	V711M	0.46
COAD	chr10	102148888	Missense_Mutation	NA	F1563L	0.31	RRM_1
COAD	chr10	102141523	Silent	NA	A1005A	0.33
COAD	chr10	102149224	Missense_Mutation	novel	A1596T	0.07	RRM_1
COAD	chr10	102141449	Missense_Mutation	NA	P981S	0.33
COAD	chr10	102139816	Silent	rs749670501	P436P	0.64
COAD	chr10	102148400	Nonsense_Mutation	novel	R1477*	0.4
COAD	chr10	102140614	Frame_Shift_Del	NA	*G704Vfs30**	0.2
COAD	chr10	102138918	Missense_Mutation	rs771663512	R177C	0.26
COAD	chr10	102147389	Missense_Mutation	rs749450563	R1466Q	0.63
COAD	chr10	102139230	Missense_Mutation	novel	Q241P	0.13
COAD	chr10	102140301	Missense_Mutation	NA	G598D	0.38
COAD	chr10	102139333	Silent	NA	P275P	0.31
COAD	chr10	102147388	Nonsense_Mutation	novel	R1466*	0.26
COAD	chr10	102149250	Silent	NA	L1604L	0.23
COAD	chr10	102141148	Silent	rs760655362	P880P	0.09
COAD	chr10	102140077	Silent	NA	A523A	0.39
COAD	chr10	102140784	Missense_Mutation	NA	R759Q	0.33
COAD	chr10	102149203	Missense_Mutation	NA	R1589C	0.45	RRM_1
COAD	chr10	102140795	Missense_Mutation	rs542386144	R763C	0.28
COAD	chr10	102143078	Missense_Mutation	novel	E1177G	0.05
COAD	chr10	102141705	Missense_Mutation	rs144417602	P1066L	0.27
ESCA	chr10	102139836	Frame_Shift_Del	novel	*N444Pfs74**	0.36
ESCA	chr10	102141663	Missense_Mutation	novel	P1052L	0.17
ESCA	chr10	102140703	Missense_Mutation	NA	S732F	0.16
ESCA	chr10	102141718	Silent	novel	V1070V	0.33
GBM	chr10	102140677	Silent	rs764264530	I723I	0.33
GBM	chr10	102141085	Silent	novel	S859S	0.15
GBM	chr10	102140962	Silent	novel	C818C	0.11
GBM	chr10	102141061	Silent	novel	E851E	0.21
GBM	chr10	102141222	Missense_Mutation	novel	S905Y	0.48
GBM	chr10	102140196	Missense_Mutation	novel	D563V	0.05
GBM	chr10	102141085	Silent	novel	S859S	0.1
GBM	chr10	102149945	Missense_Mutation	novel	F1637L	0.14
GBM	chr10	102138633	Silent	novel	L119L	0.1
GBM	chr10	102139901	Frame_Shift_Del	novel	*K465Rfs15**	0.2
GBM	chr10	102140942	Missense_Mutation	novel	E812Q	0.03
GBM	chr10	102140239	Silent	rs756554294	V577V	0.6
GBM	chr10	102140859	Missense_Mutation	novel	E784A	0.17
GBM	chr10	102141357	Missense_Mutation	novel	P950R	0.11
GBM	chr10	102149937	Missense_Mutation	novel	E1635Q	0.09
HNSC	chr10	102149973	Missense_Mutation	novel	D1647H	0.2
HNSC	chr10	102147019	Missense_Mutation	novel	P1343A	0.16
HNSC	chr10	102148520	Missense_Mutation	rs776378929	R1517W	0.23
HNSC	chr10	102137940	Missense_Mutation	novel	E82K	0.49
HNSC	chr10	102141534	Missense_Mutation	rs756058587	R1009K	0.17
HNSC	chr10	102140653	Silent	NA	S715S	0.13
HNSC	chr10	102145022	Missense_Mutation	novel	G1204A	0.22
KICH	chr10	102140786	Missense_Mutation	novel	R760G	0.12
KICH	chr10	102139670	Missense_Mutation	novel	Q388K	0.38
KIRC	chr10	102147382	Silent	NA	R1464R	0.31
KIRC	chr10	102139618	Silent	novel	P370P	0.38
KIRC	chr10	102139545	Missense_Mutation	NA	L346Q	0.24
KIRC	chr10	102141416	Missense_Mutation	NA	V970I	0.29
KIRC	chr10	102138649	Missense_Mutation	rs775086501	V125M	0.2
KIRP	chr10	102140251	Missense_Mutation	novel	Q581H	0.21
KIRP	chr10	102139478	Missense_Mutation	NA	A324T	0.33
KIRP	chr10	102140639	Missense_Mutation	rs17847386	V711M	0.08
KIRP	chr10	102140486	Missense_Mutation	novel	P660S	0.43
KIRP	chr10	102146966	Missense_Mutation	rs764176836	R1325H	0.28
KIRP	chr10	102138685	Frame_Shift_Del	novel	*N137Mfs79**	0.17
LAML	chr10	102146832	Silent	novel	Q1280Q	0.34
LGG	chr10	102139816	Silent	rs749670501	P436P	0.12
LGG	chr10	102139771	Missense_Mutation	novel	K421N	0.11
LGG	chr10	102140852	Missense_Mutation	novel	L782F	0.49
LIHC	chr10	102146750	Missense_Mutation	novel	S1253C	0.27
LIHC	chr10	102149966	Silent	NA	S1644S	0.38
LIHC	chr10	102138686	Missense_Mutation	novel	N137S	0.62
LUAD	chr10	102147256	Missense_Mutation	rs368680880	R1422C	0.36
LUAD	chr10	102138669	Silent	NA	L131L	0.36
LUAD	chr10	102141319	Silent	novel	L937L	0.1
LUAD	chr10	102149294	Frame_Shift_Del	novel	*R1619Qfs24**	0.06
LUAD	chr10	102147010	Missense_Mutation	novel	A1340T	0.18
LUAD	chr10	102139897	Missense_Mutation	novel	K463N	0.22
LUAD	chr10	102139125	Missense_Mutation	novel	S206C	0.24
LUAD	chr10	102146955	Missense_Mutation	NA	W1321C	0.13
LUAD	chr10	102141133	Missense_Mutation	novel	M875I	0.3
LUAD	chr10	102147228	Silent	rs762078980	A1412A	0.2
LUAD	chr10	102148467	Missense_Mutation	NA	S1499F	0.11
LUAD	chr10	102140714	Missense_Mutation	NA	E736Q	0.3
LUAD	chr10	102140165	Missense_Mutation	rs746746156	G553C	0.39
LUAD	chr10	102138618	Splice_Site	NA	X115_splice	0.09
LUAD	chr10	102141954	Missense_Mutation	NA	P1149Q	0.26
LUAD	chr10	102138915	Missense_Mutation	NA	E176K	0.11
LUAD	chr10	102139662	Missense_Mutation	novel	S385C	0.05
LUAD	chr10	102144306	Missense_Mutation	novel	G1203C	0.09
LUAD	chr10	102147020	Missense_Mutation	rs374891266	P1343L	0.25
LUAD	chr10	102146950	Nonsense_Mutation	NA	R1320*	0.16
LUAD	chr10	102146676	Silent	NA	L1228L	0.29
LUAD	chr10	102139725	Frame_Shift_Del	novel	*L407Sfs10**	0.17
LUSC	chr10	102139310	Missense_Mutation	novel	V268L	0.13
LUSC	chr10	102141428	Missense_Mutation	rs757124491	S974G	0.23
LUSC	chr10	102148423	Silent	NA	S1484S	0.47
LUSC	chr10	102140404	Silent	novel	I632I	0.19
LUSC	chr10	102141287	Missense_Mutation	novel	P927S	0.34
LUSC	chr10	102138914	Silent	NA	P175P	0.2
LUSC	chr10	102141795	Missense_Mutation	NA	A1096V	0.41
LUSC	chr10	102138764	Missense_Mutation	NA	S163C	0.12
LUSC	chr10	102138948	Missense_Mutation	NA	G187R	0.36
LUSC	chr10	102149294	Missense_Mutation	NA	R1619L	0.29
LUSC	chr10	102139236	Missense_Mutation	NA	R243H	0.37
MESO	chr10	102147151	Missense_Mutation	rs201606390	M1387V	0.16
OV	chr10	102137870	Silent	rs574814323	A58A	0.45
OV	chr10	102150073	3'UTR	novel		0.8
OV	chr10	102141923	Missense_Mutation	rs371010227	R1139C	0.71
OV	chr10	102148872	Missense_Mutation	novel	E1558V	0.17	RRM_1
OV	chr10	102139503	Missense_Mutation	novel	E332V	0.1
OV	chr10	102147182	Missense_Mutation	novel	A1397V	0.15
OV	chr10	102141716	Missense_Mutation	novel	V1070L	0.15
OV	chr10	102140156	Missense_Mutation	NA	A550P	0.76
OV	chr10	102139352	Nonsense_Mutation	novel	E282*	0.04
OV	chr10	102139353	Missense_Mutation	novel	E282G	0.04
OV	chr10	102147191	Missense_Mutation	rs748036766	R1400Q	0.47
PAAD	chr10	102147267	Silent	novel	R1425R	0.07
PAAD	chr10	102140859	Missense_Mutation	novel	E784A	0.22
PAAD	chr10	102141262	Silent	novel	A918A	0.17
PAAD	chr10	102148866	Missense_Mutation	rs370946381	R1556Q	0.15	RRM_1
PCPG	chr10	102144262	Missense_Mutation	novel	C1188Y	0.37
PRAD	chr10	102148883	Missense_Mutation	novel	R1562G	0.08	RRM_1
PRAD	chr10	102146885	Missense_Mutation	NA	Y1298C	0.21
PRAD	chr10	102146894	Missense_Mutation	rs746405708	R1301Q	0.51
PRAD	chr10	102141065	Missense_Mutation	novel	P853S	0.5
PRAD	chr10	102148440	Missense_Mutation	rs201734122	S1490L	0.42
READ	chr10	102133175	Missense_Mutation	NA	S36N	0.22
READ	chr10	102141606	Missense_Mutation	rs761599601	S1033L	0.23
READ	chr10	102139878	Missense_Mutation	NA	R457Q	0.19
READ	chr10	102139558	Silent	NA	G350G	0.23
READ	chr10	102140290	Frame_Shift_Ins	NA	*T595Nfs14**	0.3
SARC	chr10	102141539	Missense_Mutation	novel	V1011F	0.47
SARC	chr10	102138625	Missense_Mutation	novel	L117I	0.56
SKCM	chr10	102138929	Silent	NA	I180I	0.43
SKCM	chr10	102141442	Silent	novel	T978T	0.42
SKCM	chr10	102147100	Missense_Mutation	NA	L1370V	0.29
SKCM	chr10	102148890	Missense_Mutation	novel	S1564F	0.34	RRM_1
SKCM	chr10	102141212	Missense_Mutation	NA	L902F	0.22
SKCM	chr10	102138029	Silent	NA	S111S	0.36
SKCM	chr10	102138695	Missense_Mutation	NA	S140F	0.33
SKCM	chr10	102140703	Missense_Mutation	NA	S732F	0.33
SKCM	chr10	102139798	Silent	NA	P430P	0.29
SKCM	chr10	102141850	Silent	NA	P1114P	0.33
SKCM	chr10	102141922	Silent	novel	A1138A	0.3
SKCM	chr10	102140855	Missense_Mutation	NA	P783S	0.19
SKCM	chr10	102147122	Missense_Mutation	novel	S1377F	0.47
SKCM	chr10	102149292	Silent	rs760085551	G1618G	0.37
SKCM	chr10	102149293	Nonsense_Mutation	novel	R1619*	0.36
SKCM	chr10	102140072	Silent	NA	R522R	0.47
SKCM	chr10	102139416	Missense_Mutation	novel	S303F	0.61
SKCM	chr10	102147370	Missense_Mutation	novel	P1460S	0.4
SKCM	chr10	102148641	Missense_Mutation	NA	R1522C	0.26
SKCM	chr10	102141991	Silent	NA	F1161F	0.21
SKCM	chr10	102149997	Silent	NA	L1655L	0.22
SKCM	chr10	102141509	Missense_Mutation	NA	P1001S	0.37
SKCM	chr10	102139877	Nonsense_Mutation	novel	R457*	0.17
SKCM	chr10	102139332	Missense_Mutation	rs780690524	P275L	0.32
SKCM	chr10	102141311	Missense_Mutation	NA	P935S	0.19
SKCM	chr10	102147363	Silent	NA	S1457S	0.45
SKCM	chr10	102140384	Missense_Mutation	rs777545017	P626S	0.15
SKCM	chr10	102146985	Silent	novel	I1331I	0.23
SKCM	chr10	102141701	Missense_Mutation	novel	H1065Y	0.09
SKCM	chr10	102140798	Nonsense_Mutation	novel	Q764*	0.3
SKCM	chr10	102147352	Missense_Mutation	NA	R1454W	0.08
SKCM	chr10	102140529	Missense_Mutation	NA	V674A	0.19
SKCM	chr10	102140088	Missense_Mutation	NA	A527V	0.4
SKCM	chr10	102138948	Missense_Mutation	NA	G187W	0.25
SKCM	chr10	102147142	Missense_Mutation	rs766885739	R1384W	0.21
SKCM	chr10	102139322	Missense_Mutation	novel	P272S	0.48
SKCM	chr10	102141269	Missense_Mutation	NA	P921S	0.18
STAD	chr10	102139721	Missense_Mutation	novel	V405I	0.24
STAD	chr10	102139410	Missense_Mutation	NA	S301T	0.29
STAD	chr10	102148646	Silent	NA	S1523S	0.1
STAD	chr10	102148884	Missense_Mutation	NA	R1562M	0.28	RRM_1
STAD	chr10	102148423	Silent	rs558136788	S1484S	0.2
STAD	chr10	102145037	Missense_Mutation	rs756230353	Q1209R	0.17
STAD	chr10	102139689	Missense_Mutation	NA	L394P	0.18
STAD	chr10	102140524	Missense_Mutation	novel	D672E	0.11
STAD	chr10	102147368	Frame_Shift_Del	NA	*P1461Hfs79**	0.33
STAD	chr10	102141905	In_Frame_Ins	novel	A1134dup	0.18
STAD	chr10	102141401	Frame_Shift_Del	novel	*P966Lfs114**	0.22
STAD	chr10	102140614	Frame_Shift_Del	NA	*G704Vfs30**	0.27
STAD	chr10	102140222	Missense_Mutation	rs752004219	T572A	0.06
STAD	chr10	102148491	Frame_Shift_Del	NA	*R1509Afs31**	0.38
STAD	chr10	102139324	Silent	rs756977690	P272P	0.12
STAD	chr10	102149976	Missense_Mutation	NA	S1648P	0.31
STAD	chr10	102138919	Missense_Mutation	rs773022710	R177H	0.23
STAD	chr10	102141306	Missense_Mutation	NA	G933D	0.42
THCA	chr10	102148486	Silent	NA	S1505S	0.12
THCA	chr10	102139445	Missense_Mutation	NA	H313Y	0.29
UCEC	chr10	102137998	Missense_Mutation	novel	S101C	0.32
UCEC	chr10	102149204	Missense_Mutation	NA	R1589H	0.23	RRM_1
UCEC	chr10	102148641	Missense_Mutation	NA	R1522C	0.04
UCEC	chr10	102138918	Missense_Mutation	rs771663512	R177C	0.39
UCEC	chr10	102143062	Silent	novel	L1172L	0.39
UCEC	chr10	102144270	Missense_Mutation	novel	P1191T	0.4
UCEC	chr10	102141320	Frame_Shift_Del	rs768056539	*P940Hfs6**	0.35
UCEC	chr10	102141867	Missense_Mutation	NA	A1120V	0.33
UCEC	chr10	102140189	Missense_Mutation	novel	L561M	0.33
UCEC	chr10	102146942	Missense_Mutation	novel	V1317A	0.3
UCEC	chr10	102147069	Silent	novel	S1359S	0.49
UCEC	chr10	102147291	Silent	novel	G1433G	0.47
UCEC	chr10	102140852	Missense_Mutation	novel	L782F	0.53
UCEC	chr10	102138751	Missense_Mutation	NA	R159W	0.26
UCEC	chr10	102139807	Silent	rs745908303	V433V	0.3
UCEC	chr10	102144257	Missense_Mutation	NA	K1186N	0.16
UCEC	chr10	102144265	Missense_Mutation	novel	P1189H	0.24
UCEC	chr10	102147259	Nonsense_Mutation	NA	R1423*	0.4
UCEC	chr10	102148476	Missense_Mutation	rs752900930	R1502H	0.11
UCEC	chr10	102141122	Missense_Mutation	NA	P872S	0.35
UCEC	chr10	102148820	Nonsense_Mutation	novel	E1541*	0.31
UCEC	chr10	102147385	Missense_Mutation	novel	W1465R	0.31
UCEC	chr10	102140745	Missense_Mutation	novel	A746D	0.3
UCEC	chr10	102146737	Missense_Mutation	novel	A1249T	0.33
UCEC	chr10	102147275	Missense_Mutation	rs112375415	R1428H	0.53
UCEC	chr10	102148481	Nonsense_Mutation	novel	R1504*	0.33
UCEC	chr10	102139455	Missense_Mutation	NA	C316Y	0.33
UCEC	chr10	102148440	Missense_Mutation	rs201734122	S1490L	0.3
UCEC	chr10	102148866	Missense_Mutation	rs370946381	R1556Q	0.54	RRM_1
UCEC	chr10	102150141	3'UTR	novel		0.23
UCEC	chr10	102141985	Missense_Mutation	novel	Q1159H	0.42
UCEC	chr10	102145067	Missense_Mutation	novel	A1219V	0.44
UCEC	chr10	102139959	Missense_Mutation	rs200642961	R484H	0.52
UCEC	chr10	102140959	Missense_Mutation	novel	I817M	0.7
UCEC	chr10	102148686	Missense_Mutation	novel	R1537C	0.47
UCEC	chr10	102148850	Missense_Mutation	novel	P1551S	0.4	RRM_1
UCEC	chr10	102149310	Missense_Mutation	novel	K1624N	0.35
UCEC	chr10	102141319	Frame_Shift_Ins	rs775630647	*P941Tfs75**	0.47
UCEC	chr10	102149964	Missense_Mutation	novel	S1644G	0.46
UCEC	chr10	102147076	Nonsense_Mutation	NA	Q1362*	0.13
UCEC	chr10	102138731	Missense_Mutation	novel	S152L	0.39
UCEC	chr10	102150141	3'UTR	novel		0.41
UCEC	chr10	102148894	Silent	rs781016346	V1565V	0.36
UCEC	chr10	102150119	3'UTR	novel		0.33
UCEC	chr10	102140222	Missense_Mutation	rs752004219	T572A	0.41
UCEC	chr10	102148422	Missense_Mutation	NA	S1484L	0.41
UCEC	chr10	102140784	Missense_Mutation	NA	R759Q	0.18
UCEC	chr10	102141606	Missense_Mutation	rs761599601	S1033L	0.5
UCEC	chr10	102139263	Missense_Mutation	novel	V252E	0.35
UCEC	chr10	102147209	Missense_Mutation	rs776919435	R1406Q	0.6
UCEC	chr10	102141888	Missense_Mutation	novel	S1127N	0.33
UCEC	chr10	102148401	Missense_Mutation	NA	R1477Q	0.31
UCEC	chr10	102150151	3'UTR	novel		0.29
UCEC	chr10	102139807	Silent	rs745908303	V433V	0.15
UCEC	chr10	102141097	Missense_Mutation	rs745337054	Q863H	0.22
UCEC	chr10	102148857	Missense_Mutation	rs763766248	R1553H	0.38	RRM_1
UCEC	chr10	102141940	Silent	rs371094314	S1144S	0.12
UCEC	chr10	102147306	Silent	rs758470365	S1438S	0.15
UCEC	chr10	102147306	Silent	rs758470365	S1438S	0.26
UCEC	chr10	102140614	Frame_Shift_Del	NA	*G704Vfs30**	0.32
UCEC	chr10	102141306	Missense_Mutation	NA	G933D	0.38
UCEC	chr10	102145023	Silent	NA	G1204G	0.41
UCEC	chr10	102148401	Missense_Mutation	NA	R1477Q	0.44
UCEC	chr10	102138717	Silent	novel	D147D	0.38
UCEC	chr10	102140107	Missense_Mutation	NA	E533D	0.47
UCEC	chr10	102138894	Frame_Shift_Ins	novel	*R172Lfs45**	0.42
UCEC	chr10	102147373	Missense_Mutation	novel	P1461S	0.47
UCEC	chr10	102139252	Silent	NA	E248E	0.31
UCEC	chr10	102149294	Missense_Mutation	NA	R1619Q	0.3
UCEC	chr10	102137920	Missense_Mutation	novel	D75G	0.46
UCEC	chr10	102138744	Silent	novel	V156V	0.22
UCEC	chr10	102140230	Silent	novel	L574L	0.16
UCEC	chr10	102141334	Silent	rs746788162	T942T	0.17
UCEC	chr10	102143058	Silent	NA	S1170S	0.32
UCEC	chr10	102147125	Missense_Mutation	novel	P1378H	0.19
UCEC	chr10	102149948	Silent	novel	D1638D	0.18
UCEC	chr10	102140791	Silent	novel	Q761Q	0.59
UCEC	chr10	102149268	Silent	novel	Q1610Q	0.24
UCEC	chr10	102146903	Frame_Shift_Del	novel	*P1306Qfs7**	0.07
UCEC	chr10	102148656	Missense_Mutation	NA	Y1527H	0.34
UCEC	chr10	102147332	Missense_Mutation	novel	S1447L	0.38
UCEC	chr10	102148517	Missense_Mutation	rs760651788	R1516W	0.27
UCEC	chr10	102148873	Silent	rs141475708	E1558E	0.41
UCEC	chr10	102137869	Missense_Mutation	rs769958270	A58V	0.38
UCEC	chr10	102139236	Missense_Mutation	NA	R243H	0.21
UCEC	chr10	102140385	Missense_Mutation	novel	P626L	0.41
UCEC	chr10	102140975	Missense_Mutation	novel	G823C	0.29
UCEC	chr10	102149189	Missense_Mutation	novel	G1584D	0.48	RRM_1
UCS	chr10	102141514	Silent	novel	L1002L	0.1
UCS	chr10	102140677	Silent	novel	I723I	0.13
UCS	chr10	102139156	Missense_Mutation	novel	E216D	0.06
UCS	chr10	102139382	Missense_Mutation	novel	M292L	0.08

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1	0.19593
CHOL	DEL	0.2222	0.048655
COAD	DEL	0.1796	9.4741e-07
MESO	DEL	0.2644	0.00015289
OV	DEL	0.3851	5.3759e-12
PAAD	DEL	0.1359	0.169
READ	DEL	0.2364	0.014135
THCA	DEL	0.014	0.011063
THYM	DEL	0.0325	0.10563
UCS	DEL	0.3036	0.1218

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00061	Kaplan-Meier Survival Analysis
SARC	0.016	Kaplan-Meier Survival Analysis
MESO	0.0015	Kaplan-Meier Survival Analysis
ACC	0.00014	Kaplan-Meier Survival Analysis
UCS	0.042	Kaplan-Meier Survival Analysis
SKCM	0.00096	Kaplan-Meier Survival Analysis
ESCA	0.049	Kaplan-Meier Survival Analysis
KIRP	0.002	Kaplan-Meier Survival Analysis
COAD	0.034	Kaplan-Meier Survival Analysis
PCPG	0.023	Kaplan-Meier Survival Analysis
BLCA	0.02	Kaplan-Meier Survival Analysis
LIHC	0.041	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

GWAS

PPI

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000148840 (Gene tree)
Gene ID: 23082
Gene Symbol: PPRC1
Alias: PRC|KIAA0595|MGC74642
Full Name: PPARG related coactivator 1
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Plus strand
Length: 17,340 bases
Position: chr10:102,132,994-102,150,333
Accession: 30025
Summary: The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPAR-gamma coactivator 1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000359029	RRM_1	PF00076.22	4.6e-08	1	1
ENSP00000399743	RRM_1	PF00076.22	1.2e-07	1	1
ENSP00000278070	RRM_1	PF00076.22	1.5e-07	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	polyT & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	PolyT & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000462933	PPRC1-204	729	-	-	- (aa)	-	-
ENST00000413464	PPRC1-203	4580	XM_011539552	ENSP00000399743	1400 (aa)	XP_011537854	E7EVG6
ENST00000489648	PPRC1-205	744	-	-	- (aa)	-	-
ENST00000278070	PPRC1-201	5330	XM_005269656	ENSP00000278070	1664 (aa)	XP_005269713	Q5VV67
ENST00000370012	PPRC1-202	2163	-	ENSP00000359029	631 (aa)	-	X6R7H2
ENST00000495914	PPRC1-206	564	-	-	- (aa)	-	-

Gene Model

Click here to download 's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000148840	rs138828258	10	102142302	C	Mean corpuscular hemoglobin	27863252	[0.019-0.032] unit increase	0.02549926	EFO_0004527

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000148840's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000148840	PPRC1	96	100.000	ENSAMEG00000017685	PPRC1	100	84.952	Ailuropoda_melanoleuca
ENSG00000148840	PPRC1	54	58.434	ENSACIG00000022532	pprc1	71	68.702	Amphilophus_citrinellus
ENSG00000148840	PPRC1	65	76.087	ENSACAG00000012404	PPRC1	58	48.995	Anolis_carolinensis
ENSG00000148840	PPRC1	100	97.152	ENSANAG00000029448	PPRC1	96	100.000	Aotus_nancymaae
ENSG00000148840	PPRC1	96	100.000	ENSBTAG00000007427	PPRC1	96	100.000	Bos_taurus
ENSG00000148840	PPRC1	100	96.209	ENSCJAG00000017812	PPRC1	96	100.000	Callithrix_jacchus
ENSG00000148840	PPRC1	96	100.000	ENSCAFG00000010040	PPRC1	100	82.878	Canis_familiaris
ENSG00000148840	PPRC1	96	100.000	ENSCAFG00020010030	PPRC1	99	100.000	Canis_lupus_dingo
ENSG00000148840	PPRC1	95	100.000	ENSCHIG00000011471	PPRC1	96	100.000	Capra_hircus
ENSG00000148840	PPRC1	100	83.043	ENSCAPG00000016649	-	100	82.726	Cavia_aperea
ENSG00000148840	PPRC1	97	98.639	ENSCPOG00000032149	PPRC1	96	100.000	Cavia_porcellus
ENSG00000148840	PPRC1	100	96.677	ENSCCAG00000014910	PPRC1	96	100.000	Cebus_capucinus
ENSG00000148840	PPRC1	100	97.480	ENSCATG00000029634	PPRC1	96	100.000	Cercocebus_atys
ENSG00000148840	PPRC1	96	99.296	ENSCLAG00000001364	PPRC1	96	100.000	Chinchilla_lanigera
ENSG00000148840	PPRC1	100	97.468	ENSCSAG00000005471	PPRC1	100	95.616	Chlorocebus_sabaeus
ENSG00000148840	PPRC1	100	87.836	ENSCHOG00000006574	PPRC1	100	81.579	Choloepus_hoffmanni
ENSG00000148840	PPRC1	100	97.943	ENSCANG00000037336	PPRC1	100	96.524	Colobus_angolensis_palliatus
ENSG00000148840	PPRC1	96	100.000	ENSCGRG00001011726	Pprc1	81	100.000	Cricetulus_griseus_chok1gshd
ENSG00000148840	PPRC1	90	100.000	ENSCGRG00000012760	Pprc1	80	100.000	Cricetulus_griseus_crigri
ENSG00000148840	PPRC1	96	100.000	ENSDNOG00000040730	PPRC1	100	81.339	Dasypus_novemcinctus
ENSG00000148840	PPRC1	96	100.000	ENSDORG00000001046	Pprc1	100	80.359	Dipodomys_ordii
ENSG00000148840	PPRC1	95	97.872	ENSETEG00000019254	PPRC1	92	91.961	Echinops_telfairi
ENSG00000148840	PPRC1	95	100.000	ENSEASG00005007583	PPRC1	100	83.492	Equus_asinus_asinus
ENSG00000148840	PPRC1	96	100.000	ENSECAG00000009482	PPRC1	96	100.000	Equus_caballus
ENSG00000148840	PPRC1	98	83.923	ENSEEUG00000014216	PPRC1	80	83.241	Erinaceus_europaeus
ENSG00000148840	PPRC1	96	100.000	ENSFCAG00000001238	PPRC1	96	100.000	Felis_catus
ENSG00000148840	PPRC1	91	99.296	ENSFDAG00000011496	PPRC1	79	100.000	Fukomys_damarensis
ENSG00000148840	PPRC1	100	100.000	ENSGGOG00000002155	PPRC1	100	99.219	Gorilla_gorilla
ENSG00000148840	PPRC1	100	87.855	ENSHGLG00000002783	-	100	86.593	Heterocephalus_glaber_female
ENSG00000148840	PPRC1	100	87.855	ENSHGLG00100017775	-	100	86.593	Heterocephalus_glaber_male
ENSG00000148840	PPRC1	100	92.393	ENSSTOG00000002156	-	100	92.710	Ictidomys_tridecemlineatus
ENSG00000148840	PPRC1	100	80.696	ENSJJAG00000005177	-	100	79.386	Jaculus_jaculus
ENSG00000148840	PPRC1	96	100.000	ENSLAFG00000014232	PPRC1	85	87.437	Loxodonta_africana
ENSG00000148840	PPRC1	100	97.638	ENSMFAG00000038589	PPRC1	100	97.638	Macaca_fascicularis
ENSG00000148840	PPRC1	100	97.480	ENSMMUG00000001186	PPRC1	96	100.000	Macaca_mulatta
ENSG00000148840	PPRC1	100	97.165	ENSMNEG00000031603	PPRC1	100	96.043	Macaca_nemestrina
ENSG00000148840	PPRC1	100	97.480	ENSMLEG00000035092	PPRC1	96	100.000	Mandrillus_leucophaeus
ENSG00000148840	PPRC1	97	55.368	ENSMGAG00000010023	PPRC1	70	87.943	Meleagris_gallopavo
ENSG00000148840	PPRC1	96	98.582	ENSMAUG00000016674	Pprc1	80	98.582	Mesocricetus_auratus
ENSG00000148840	PPRC1	96	100.000	ENSMICG00000011794	PPRC1	96	100.000	Microcebus_murinus
ENSG00000148840	PPRC1	100	83.360	ENSMOCG00000018283	-	100	80.673	Microtus_ochrogaster
ENSG00000148840	PPRC1	91	70.154	ENSMODG00000011467	-	69	90.071	Monodelphis_domestica
ENSG00000148840	PPRC1	96	98.592	MGP_CAROLIEiJ_G0023026	Pprc1	81	99.291	Mus_caroli
ENSG00000148840	PPRC1	96	98.592	ENSMUSG00000055491	Pprc1	81	99.291	Mus_musculus
ENSG00000148840	PPRC1	96	98.592	MGP_PahariEiJ_G0014516	Pprc1	80	99.291	Mus_pahari
ENSG00000148840	PPRC1	97	83.604	MGP_SPRETEiJ_G0023947	Pprc1	81	99.291	Mus_spretus
ENSG00000148840	PPRC1	100	81.016	ENSMPUG00000016888	PPRC1	96	100.000	Mustela_putorius_furo
ENSG00000148840	PPRC1	96	99.291	ENSMLUG00000006217	PPRC1	100	81.606	Myotis_lucifugus
ENSG00000148840	PPRC1	96	100.000	ENSNGAG00000016516	Pprc1	81	100.000	Nannospalax_galili
ENSG00000148840	PPRC1	100	96.098	ENSNLEG00000014996	PPRC1	100	96.038	Nomascus_leucogenys
ENSG00000148840	PPRC1	53	91.200	ENSMEUG00000013795	-	54	91.200	Notamacropus_eugenii
ENSG00000148840	PPRC1	100	84.567	ENSOPRG00000009346	PPRC1	91	91.558	Ochotona_princeps
ENSG00000148840	PPRC1	99	86.603	ENSODEG00000006985	-	99	86.284	Octodon_degus
ENSG00000148840	PPRC1	64	88.496	ENSOANG00000007826	-	71	90.654	Ornithorhynchus_anatinus
ENSG00000148840	PPRC1	96	100.000	ENSOCUG00000000510	PPRC1	100	82.088	Oryctolagus_cuniculus
ENSG00000148840	PPRC1	96	100.000	ENSOGAG00000016354	PPRC1	100	86.495	Otolemur_garnettii
ENSG00000148840	PPRC1	92	100.000	ENSOARG00000017509	PPRC1	66	100.000	Ovis_aries
ENSG00000148840	PPRC1	100	97.477	ENSPPAG00000032544	PPRC1	100	97.477	Pan_paniscus
ENSG00000148840	PPRC1	96	100.000	ENSPPRG00000004274	PPRC1	96	100.000	Panthera_pardus
ENSG00000148840	PPRC1	96	100.000	ENSPTIG00000013709	PPRC1	96	100.000	Panthera_tigris_altaica
ENSG00000148840	PPRC1	100	100.000	ENSPTRG00000002883	PPRC1	100	99.099	Pan_troglodytes
ENSG00000148840	PPRC1	100	97.323	ENSPANG00000021042	PPRC1	96	100.000	Papio_anubis
ENSG00000148840	PPRC1	100	85.737	ENSPEMG00000016590	-	99	83.079	Peromyscus_maniculatus_bairdii
ENSG00000148840	PPRC1	83	88.435	ENSPCIG00000029013	PPRC1	73	90.071	Phascolarctos_cinereus
ENSG00000148840	PPRC1	90	99.291	ENSPCAG00000008277	PPRC1	96	80.550	Procavia_capensis
ENSG00000148840	PPRC1	96	99.291	ENSPCOG00000025917	PPRC1	96	99.291	Propithecus_coquereli
ENSG00000148840	PPRC1	88	100.000	ENSPVAG00000004048	PPRC1	81	100.000	Pteropus_vampyrus
ENSG00000148840	PPRC1	96	99.291	ENSRNOG00000018561	Pprc1	81	99.291	Rattus_norvegicus
ENSG00000148840	PPRC1	100	97.785	ENSRBIG00000027711	PPRC1	100	96.367	Rhinopithecus_bieti
ENSG00000148840	PPRC1	100	97.627	ENSRROG00000044599	PPRC1	100	96.216	Rhinopithecus_roxellana
ENSG00000148840	PPRC1	100	97.310	ENSSBOG00000021902	PPRC1	96	100.000	Saimiri_boliviensis_boliviensis
ENSG00000148840	PPRC1	57	64.463	ENSSHAG00000008862	-	100	63.912	Sarcophilus_harrisii
ENSG00000148840	PPRC1	89	100.000	ENSSARG00000004030	PPRC1	96	86.824	Sorex_araneus
ENSG00000148840	PPRC1	96	100.000	ENSSSCG00000010575	PPRC1	100	81.927	Sus_scrofa
ENSG00000148840	PPRC1	86	58.217	ENSTGUG00000009839	-	100	61.326	Taeniopygia_guttata
ENSG00000148840	PPRC1	96	100.000	ENSTTRG00000014966	PPRC1	100	84.491	Tursiops_truncatus
ENSG00000148840	PPRC1	100	91.325	ENSUAMG00000028058	PPRC1	96	100.000	Ursus_americanus
ENSG00000148840	PPRC1	96	100.000	ENSUMAG00000023041	PPRC1	96	100.000	Ursus_maritimus
ENSG00000148840	PPRC1	96	100.000	ENSVVUG00000002566	PPRC1	96	100.000	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003712	transcription coregulator activity	21873635.	IBA	Function
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0007005	mitochondrion organization	-	TAS	Process
GO:0008134	transcription factor binding	21873635.	IBA	Function
GO:0030374	nuclear receptor transcription coactivator activity	21873635.	IBA	Function
GO:0045944	positive regulation of transcription by RNA polymerase II	21873635.	IBA	Process
GO:0051091	positive regulation of DNA-binding transcription factor activity	21873635.	IBA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

GWAS

PPI

Ortholog

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.