EuRBPDB

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TCGA tumor abbreviations
  • ACCAdrenocortical carcinoma
  • BLCABladder Urothelial Carcinoma
  • BRCABreast invasive carcinoma
  • CESCCervical squamous cell carcinoma and endocervical adenocarcinoma
  • CHOLCholangio carcinoma
  • COADColon adenocarcinoma
  • DLBCLymphoid Neoplasm Diffuse Large B-cell Lymphoma
  • ESCAEsophageal carcinoma
  • GBMGlioblastoma multiforme
  • HNSCHead and Neck squamous cell carcinoma
  • KICHKidney Chromophobe
  • KIRCKidney renal clear cell carcinoma
  • KIRPKidney renal papillary cell carcinoma
  • LAMLAcute Myeloid Leukemia
  • LGGBrain Lower Grade Glioma
  • LIHCLiver hepatocellular carcinoma
  • LUADLung adenocarcinoma
  • LUSCLung squamous cell carcinoma
  • MESOMesothelioma
  • OVOvarian serous cystadenocarcinoma
  • PAADPancreatic adenocarcinoma
  • PCPGPheochromocytoma and Paraganglioma
  • PRADProstate adenocarcinoma
  • READRectum adenocarcinoma
  • SARCSarcoma
  • SKCMSkin Cutaneous Melanoma
  • STADStomach adenocarcinoma
  • TGCTThyroid carcinoma
  • THCAThyroid carcinoma
  • THYMThymoma
  • UCECUterine Corpus Endometrial Carcinoma
  • UCSUterine Carcinosarcoma
  • UVMUveal Melanoma

Note: Click here to get the extension of tumor abbreviations.


  • Cancer Related Information
  • Basic Information

Differential Expression

Expression in 33 cancers

Mutations
CancerChrPosition Mutation TypedbSNPProtein-change Allele FreqRBD
BLCAchr1228101399In_Frame_DelnovelH197_K203del0.22
BLCAchr1228101357Missense_MutationnovelS217F0.11
BLCAchr1228101365Silentrs778053863A214A0.26
BLCAchr1228102353Missense_MutationNAR135P0.2
BLCAchr1228101144Missense_MutationnovelG260V0.41
BLCAchr1228101139Missense_MutationNAE262K0.27
BRCAchr1228101425Frame_Shift_DelnovelR195Gfs*820.17
CESCchr1228101386Silentrs140017352E207E0.34
CESCchr1228102021IntronNA0.22
CESCchr1228102122Nonsense_MutationNAS164*0.14
CESCchr1228101906Intronnovel0.39
COADchr1228102654Missense_MutationNAL94M0.27
COADchr1228101450Missense_MutationNAK186R0.18
COADchr1228101396In_Frame_Delrs370819690K204del0.31
HNSCchr1228101210Missense_MutationnovelC238F0.52
HNSCchr1228103022Missense_MutationnovelR41H0.33
HNSCchr12281033025'UTRnovel0.44
HNSCchr1228101152Frame_Shift_InsnovelH257Qfs*20.1
KIRPchr1228103224Missense_MutationNAF2V0.57
LGGchr1228101167Silentrs750496770P252P0.27
LIHCchr1228102143Missense_MutationnovelG157E0.33
LIHCchr1228102659Splice_SitenovelX82_splice0.23
LUADchr1228102320Missense_MutationNAS146C0.13
LUADchr12281010613'UTRnovel0.4
LUADchr12281010843'UTRnovel0.14
LUADchr1228101387In_Frame_DelnovelD205_K206del0.46
LUSCchr1228103200Missense_MutationnovelR10G0.78
LUSCchr1228103217Missense_MutationnovelS4C0.28
OVchr12281032285'UTRnovel0.18
SKCMchr12281011053'UTRnovel0.53
STADchr12281010713'UTRnovel0.28
STADchr1228102375Missense_MutationNAV128M0.13
STADchr1228102370Silentrs768292808G129G0.33
UCECchr12281009003'UTRrs5386779400.3
UCECchr1228102325SilentnovelG144G0.31
UCECchr1228101457Missense_MutationnovelK184E0.29
UCECchr12281011213'UTRnovel0.29
UCECchr12281011013'UTRrs7477643430.33
UCECchr1228101349Missense_Mutationrs748613886S220P0.38
UCECchr1228101426Frame_Shift_DelnovelK194Efs*190.32
UCECchr1228101162Missense_Mutationrs140393278R254H0.4
UCECchr12281010623'UTRnovel0.5
UCECchr1228102670Missense_MutationnovelK88N0.63
UCECchr1228101378Missense_Mutationrs534724964R210Q0.66
UCECchr12281009223'UTRnovel0.38
UCSchr1228101212Missense_MutationnovelC237W0.09

Copy Number Variations (CNVs)
CancerTypeFreq Q-value
BLCADEL0.08090.033566
DLBCDEL0.1250.0017831
KIRCDEL0.06440.018371
LGGDEL0.03310.11599
PCPGDEL0.08020.12617
PRADDEL0.07520.00015401
READAMP0.25450.14328
SARCDEL0.29572.6086e-08
TGCTDEL0.03330.16985
THYMAMP0.1870.24554
UCECAMP0.37852.3921e-06

Survival Analysis
CancerP-value Q-value
KIRC0.00011

Kaplan-Meier Survival Analysis

SARC0.031

Kaplan-Meier Survival Analysis

ACC0.00013

Kaplan-Meier Survival Analysis

UCS0.041

Kaplan-Meier Survival Analysis

KIRP0.0026

Kaplan-Meier Survival Analysis

COAD0.014

Kaplan-Meier Survival Analysis

BLCA0.045

Kaplan-Meier Survival Analysis

READ0.0047

Kaplan-Meier Survival Analysis

LIHC0.0041

Kaplan-Meier Survival Analysis

OV0.00049

Kaplan-Meier Survival Analysis

Drugs

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Eesembl ID



Cell lines and drugs in GSE70138 or GSE92742

  • Description
  • RBPome
  • Expression
  • Transcripts
  • Gene Model
  • GWAS
  • PPI
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000143793 (Gene tree)
Gene ID
79169
Gene Symbol
C1orf35
Alias
MGC4174|MMTAG2
Full Name
chromosome 1 open reading frame 35
Gene Type
protein_coding
Species
Homo_sapiens
Status
putative
Strand
Minus strand
Length
4,686 bases
Position
chr1:228,100,726-228,105,411
Accession
19032
RBP type
non-canonical RBP
Summary
(Chromosome 1 Open Reading Frame 35) is a Protein Coding gene. Among its related pathways are Innate Immune System.
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
22681889The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts4SURIC & HEK2932012 MayBaltz AGDOI: 10.1016/j.molcel.2012.05.021
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
22658674Insights into RNA biology from an atlas of mammalian mRNA-binding proteinsRIC & Hela2012 May 31Castello ADOI: 10.1016/j.cell.2012.04.031
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & MCF72018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30352994Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome captureRIC & Jurkat2018 Oct 23Perez-Perri JIDOI:10.1038/s41467-018-06557-8
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000469781C1orf35-2032256NR_130975-- (aa)--
ENST00000472617C1orf35-2043554--- (aa)--
ENST00000491293C1orf35-206854--- (aa)--
ENST00000485896C1orf35-2051429--- (aa)--
ENST00000272139C1orf35-2011427-ENSP00000272139263 (aa)-Q9BU76
ENST00000465199C1orf35-202588--- (aa)--
ENST00000492757C1orf35-207548--- (aa)--
Gene Model
Click here to download ENSG00000143793's gene model file
GWAS
ensgIDSNPChromosomePositionSNP-risk TraitPubmedID95% CIOr or BEAT EFO ID
ENSG00000143793rs11284561228102142?Gamma glutamyl transferase levels in low alcohol consumption30589442[0.015-0.036] unit increase0.0251EFO_0004532|EFO_0007878
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000143793's network

* RBP PPI network refers to all genes directly bind to RBP
Orthologs identified by RBPome
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000143793C1orf359976.806ENSMUSG000000204412310033P09Rik9979.468Mus_musculus
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0003723RNA binding22658674.22681889.HDAFunction
GO:0005515protein binding21873635.IBAFunction
GO:0005515protein binding16189514.19060904.21044950.21516116.23602568.24965446.25416956.IPIFunction
GO:0005576extracellular region-TASComponent
GO:0034774secretory granule lumen-TASComponent
GO:0043312neutrophil degranulation-TASProcess
GO:1904813ficolin-1-rich granule lumen-TASComponent
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