EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
19693694	Identification of a novel human cancer/testis gene MAEL that is regulated by DNA methylation.	Mol Biol Rep	2010 Jun	Xiao L	doi: 10.1007/s11033-009-9741-x
27537253	MAEL expression links epithelial-mesenchymal transition and stem cell properties in colorectal cancer.	Int J Cancer	2016 Dec 1	Li Q	doi: 10.1002/ijc.30388
27926513	Mael is essential for cancer cell survival and tumorigenesis through protection of genetic integrity.	Oncotarget	2017 Jan 17	Kim SH	doi: 10.18632/oncotarget.13756.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr1	167017846	Missense_Mutation	novel	L310V	0.3	Maelstrom
BLCA	chr1	167005288	Missense_Mutation	novel	E246Q	0.13	Maelstrom
BLCA	chr1	166989764	Missense_Mutation	NA	Y54H	0.35
BLCA	chr1	166994048	Nonsense_Mutation	NA	R168*	0.45	Maelstrom
BLCA	chr1	167004298	Silent	NA	Y214Y	0.19
BLCA	chr1	167005344	Frame_Shift_Del	novel	*W265Gfs6**	0.46	Maelstrom
BLCA	chr1	167021786	Missense_Mutation	novel	N412K	0.49
BRCA	chr1	166994036	Missense_Mutation	novel	P164S	0.07	Maelstrom
BRCA	chr1	166994037	Missense_Mutation	novel	P164L	0.07	Maelstrom
BRCA	chr1	166989793	Silent	NA	A63A	0.17
BRCA	chr1	166989346	5'UTR	novel		0.17
BRCA	chr1	167005083	Missense_Mutation	NA	D219V	0.32	Maelstrom
BRCA	chr1	167021712	Missense_Mutation	rs141476246	V388I	0.29
BRCA	chr1	167005266	Silent	novel	Q238Q	0.14
BRCA	chr1	167005088	Missense_Mutation	NA	T221A	0.18	Maelstrom
BRCA	chr1	167022130	3'UTR	novel		0.23
BRCA	chr1	166992802	Missense_Mutation	novel	E148Q	0.13	Maelstrom
BRCA	chr1	166992794	Missense_Mutation	novel	S145F	0.41	Maelstrom
BRCA	chr1	167016276	Silent	NA	K300K	0.19
CESC	chr1	166992730	Frame_Shift_Ins	novel	*L126Rfs7**	0.13
CESC	chr1	166989801	Missense_Mutation	NA	G66E	0.43
CESC	chr1	166994066	Missense_Mutation	NA	A174T	0.43	Maelstrom
CESC	chr1	167004266	Missense_Mutation	NA	H204D	0.11	Maelstrom
CESC	chr1	166989346	5'UTR	novel		0.46
CESC	chr1	166989938	Intron	rs550879943		0.65
CHOL	chr1	166994040	Missense_Mutation	rs199624416	R165Q	0.14	Maelstrom
COAD	chr1	166989937	Intron	novel		0.14
COAD	chr1	167021758	Missense_Mutation	novel	S403F	0.25
COAD	chr1	167017951	Missense_Mutation	novel	R345C	0.19
COAD	chr1	167004261	Missense_Mutation	NA	F202C	0.06	Maelstrom
COAD	chr1	167021125	Missense_Mutation	NA	S361Y	0.12
COAD	chr1	167021715	Missense_Mutation	rs202037854	R389W	0.28
COAD	chr1	166989955	Intron	novel		0.47
COAD	chr1	166989348	5'UTR	novel		0.3
COAD	chr1	166989419	Missense_Mutation	novel	R23W	0.4
COAD	chr1	166992707	Frame_Shift_Ins	novel	*L118Ffs5**	0.37
COAD	chr1	167004246	Missense_Mutation	novel	Q197R	0.11	Maelstrom
COAD	chr1	166989382	Silent	novel	A10A	0.19
COAD	chr1	167005351	Nonsense_Mutation	NA	R267*	0.09	Maelstrom
COAD	chr1	167021907	3'UTR	novel		0.23
COAD	chr1	166989391	Missense_Mutation	NA	F13L	0.19
COAD	chr1	166989946	Intron	novel		0.27
COAD	chr1	167017951	Missense_Mutation	novel	R345C	0.06
COAD	chr1	167021159	Splice_Region	NA	I372I	0.15
ESCA	chr1	167005280	Missense_Mutation	novel	L243R	0.41	Maelstrom
ESCA	chr1	167021708	Missense_Mutation	novel	S386R	0.17
GBM	chr1	167005351	Nonsense_Mutation	NA	R267*	0.04	Maelstrom
GBM	chr1	167021783	Silent	novel	S411S	0.09
GBM	chr1	167017838	Missense_Mutation	novel	S307N	0.21	Maelstrom
HNSC	chr1	167021884	3'UTR	novel		0.44
HNSC	chr1	166992725	Missense_Mutation	novel	S122I	0.51
HNSC	chr1	167021092	Missense_Mutation	novel	R350M	0.22
HNSC	chr1	167021827	Missense_Mutation	novel	G426A	0.1
HNSC	chr1	167005395	Splice_Region	novel	T281T	0.34
HNSC	chr1	167017960	Splice_Site	novel	X347_splice	0.3
HNSC	chr1	167016284	Missense_Mutation	rs773190752	A303V	0.14	Maelstrom
HNSC	chr1	167016284	Missense_Mutation	rs773190752	A303V	0.16	Maelstrom
HNSC	chr1	167017836	Missense_Mutation	novel	I306M	0.26	Maelstrom
KIRC	chr1	166992765	Silent	NA	L135L	0.21
KIRP	chr1	167005324	Missense_Mutation	NA	L258I	0.46	Maelstrom
LAML	chr1	166992776	Missense_Mutation	NA	I139T	0.49	Maelstrom
LAML	chr1	166992778	Missense_Mutation	novel	G140S	0.07	Maelstrom
LGG	chr1	167017943	Missense_Mutation	novel	D342V	0.09
LGG	chr1	166989394	Silent	NA	F14F	0.5
LGG	chr1	167004293	Missense_Mutation	novel	I213V	0.3	Maelstrom
LIHC	chr1	166989423	Missense_Mutation	rs756146420	R24Q	0.11
LIHC	chr1	167005108	Silent	NA	L227L	0.26
LIHC	chr1	167022080	3'UTR	novel		0.24
LIHC	chr1	167005372	Missense_Mutation	NA	M274L	0.05	Maelstrom
LIHC	chr1	167021748	Missense_Mutation	NA	I400V	0.28
LIHC	chr1	166989990	Intron	novel		0.35
LUAD	chr1	167004178	Splice_Site	NA	X175_splice	0.05
LUAD	chr1	166989817	Silent	rs761727927	P71P	0.24
LUAD	chr1	167005336	Missense_Mutation	novel	S262P	0.1	Maelstrom
LUAD	chr1	167005280	Missense_Mutation	novel	L243R	0.27	Maelstrom
LUAD	chr1	167021711	Silent	rs146423777	S387S	0.53
LUAD	chr1	167004218	Missense_Mutation	rs780212800	R188S	0.3	Maelstrom
LUAD	chr1	166991413	Missense_Mutation	novel	M87I	0.32
LUAD	chr1	167016230	Missense_Mutation	NA	W285S	0.39	Maelstrom
LUAD	chr1	166989816	Missense_Mutation	NA	P71L	0.52
LUAD	chr1	167017950	Silent	novel	G344G	0.09
LUAD	chr1	167021124	Missense_Mutation	novel	S361T	0.11
LUAD	chr1	167021683	Missense_Mutation	novel	R378M	0.28
LUAD	chr1	167021684	Missense_Mutation	novel	R378S	0.28
LUAD	chr1	167021136	Nonsense_Mutation	novel	E365*	0.16
LUSC	chr1	167021091	Missense_Mutation	novel	R350W	0.61
LUSC	chr1	167021836	Missense_Mutation	novel	S429Y	0.3
LUSC	chr1	167021767	Missense_Mutation	NA	N406S	0.2
LUSC	chr1	167005111	Silent	rs753675290	K228K	0.15
LUSC	chr1	166994061	Missense_Mutation	NA	Q172L	0.32	Maelstrom
LUSC	chr1	167005109	Nonsense_Mutation	novel	K228*	0.47	Maelstrom
LUSC	chr1	166992841	Missense_Mutation	novel	G161R	0.36	Maelstrom
LUSC	chr1	167017946	Missense_Mutation	NA	A343E	0.27
LUSC	chr1	166992798	Silent	NA	L146L	0.26
OV	chr1	167021851	Missense_Mutation	novel	S434Y	0.29
PAAD	chr1	167021786	Missense_Mutation	NA	N412K	0.16
READ	chr1	167021146	Frame_Shift_Ins	NA	*N369Kfs6**	0.19
READ	chr1	167005351	Nonsense_Mutation	NA	R267*	0.41	Maelstrom
SARC	chr1	167021944	3'UTR	novel		0.7
SKCM	chr1	166989413	Missense_Mutation	NA	E21K	0.21
SKCM	chr1	166989752	Missense_Mutation	NA	E50K	0.26
SKCM	chr1	167017920	Silent	novel	V334V	0.43
SKCM	chr1	166989746	Missense_Mutation	NA	E48K	0.12
SKCM	chr1	167021780	Silent	novel	F410F	0.24
SKCM	chr1	167004200	Missense_Mutation	NA	P182S	0.23	Maelstrom
SKCM	chr1	167021979	3'UTR	novel		0.25
SKCM	chr1	166991397	Missense_Mutation	NA	L82Q	0.13
SKCM	chr1	166989334	5'UTR	novel		0.88
SKCM	chr1	166989298	5'UTR	novel		0.54
SKCM	chr1	166989817	Silent	rs761727927	P71P	0.24
SKCM	chr1	166991468	Missense_Mutation	novel	G106S	0.04
SKCM	chr1	166991469	Missense_Mutation	novel	G106D	0.04
SKCM	chr1	166994048	Nonsense_Mutation	NA	R168*	0.34	Maelstrom
SKCM	chr1	167021683	Missense_Mutation	novel	R378K	0.31
SKCM	chr1	166989352	5'UTR	novel		0.33
SKCM	chr1	166992697	Missense_Mutation	rs576124395	G113S	0.31
SKCM	chr1	167004215	Missense_Mutation	NA	E187K	0.31	Maelstrom
SKCM	chr1	167005260	Silent	NA	I236I	0.32
SKCM	chr1	166994048	Nonsense_Mutation	NA	R168*	0.52	Maelstrom
SKCM	chr1	167004280	Silent	NA	G208G	0.34
SKCM	chr1	166994030	Missense_Mutation	NA	E162K	0.55	Maelstrom
SKCM	chr1	167005351	Nonsense_Mutation	NA	R267*	0.61	Maelstrom
SKCM	chr1	167021799	Missense_Mutation	novel	L417F	0.39
SKCM	chr1	166989413	Missense_Mutation	NA	E21K	0.27
SKCM	chr1	167005324	Missense_Mutation	NA	L258F	0.39	Maelstrom
SKCM	chr1	167021840	Silent	rs776594071	F430F	0.27
SKCM	chr1	167005352	Missense_Mutation	rs754539955	R267Q	0.25	Maelstrom
SKCM	chr1	167021762	Silent	novel	S404S	0.13
SKCM	chr1	167021695	Missense_Mutation	NA	S382F	0.23
SKCM	chr1	167016258	Missense_Mutation	NA	C294W	0.16	Maelstrom
SKCM	chr1	166989823	Silent	NA	E73E	0.15
SKCM	chr1	166989805	Silent	NA	K67K	0.24
SKCM	chr1	166989806	Missense_Mutation	novel	D68N	0.24
SKCM	chr1	167004200	Missense_Mutation	NA	P182S	0.48	Maelstrom
SKCM	chr1	166994030	Missense_Mutation	NA	E162K	0.22	Maelstrom
SKCM	chr1	167005312	Nonsense_Mutation	NA	Q254*	0.26	Maelstrom
SKCM	chr1	167005334	Missense_Mutation	rs758058554	P261L	0.39	Maelstrom
SKCM	chr1	166992726	Silent	NA	S122S	0.18
SKCM	chr1	167021797	Missense_Mutation	NA	S416L	0.15
SKCM	chr1	167021797	Missense_Mutation	NA	S416L	0.32
SKCM	chr1	166989300	5'UTR	novel		0.4
SKCM	chr1	167005352	Missense_Mutation	rs754539955	R267Q	0.5	Maelstrom
SKCM	chr1	167021816	Silent	novel	S422S	0.2
SKCM	chr1	167004196	Silent	rs142019908	K180K	0.09
SKCM	chr1	167021111	Silent	NA	F356F	0.16
SKCM	chr1	167021690	Missense_Mutation	NA	K380N	0.16
SKCM	chr1	167021902	3'UTR	novel		0.52
SKCM	chr1	166994030	Missense_Mutation	NA	E162K	0.18	Maelstrom
SKCM	chr1	167021803	Missense_Mutation	NA	S418L	0.25
SKCM	chr1	167004295	Silent	NA	I213I	0.31
SKCM	chr1	167021113	Missense_Mutation	NA	S357C	0.29
SKCM	chr1	167005322	Missense_Mutation	novel	F257C	0.26	Maelstrom
SKCM	chr1	166989334	5'UTR	novel		0.16
SKCM	chr1	167021107	Missense_Mutation	NA	G355E	0.43
SKCM	chr1	166989352	5'UTR	novel		0.33
SKCM	chr1	167017862	Missense_Mutation	novel	G315E	0.48	Maelstrom
SKCM	chr1	166989779	Nonsense_Mutation	NA	R59*	0.47
STAD	chr1	167016285	Splice_Site	rs757249676	X303_splice	0.2
STAD	chr1	167005351	Nonsense_Mutation	NA	R267*	0.07	Maelstrom
STAD	chr1	166989375	Missense_Mutation	rs750796269	R8Q	0.24
STAD	chr1	167004261	Missense_Mutation	NA	F202C	0.58	Maelstrom
STAD	chr1	167016285	Splice_Site	rs757249676	X303_splice	0.1
THYM	chr1	166991439	Missense_Mutation	novel	P96L	0.07
UCEC	chr1	166989413	Missense_Mutation	NA	E21K	0.29
UCEC	chr1	166989779	Nonsense_Mutation	NA	R59*	0.26
UCEC	chr1	166989782	Nonsense_Mutation	NA	E60*	0.16
UCEC	chr1	167017844	Missense_Mutation	NA	S309Y	0.21	Maelstrom
UCEC	chr1	166989394	Silent	NA	F14F	0.6
UCEC	chr1	166992689	Missense_Mutation	rs756890370	L110P	0.29
UCEC	chr1	166989375	Missense_Mutation	novel	R8L	0.22
UCEC	chr1	167021790	Missense_Mutation	rs755796207	D414N	0.22
UCEC	chr1	167021853	Nonstop_Mutation	novel	435Qext1	0.24
UCEC	chr1	167021780	Missense_Mutation	novel	F410L	0.3
UCEC	chr1	166992702	Silent	novel	I114I	0.23
UCEC	chr1	167005351	Nonsense_Mutation	NA	R267*	0.28	Maelstrom
UCEC	chr1	166989305	5'UTR	rs371448725		0.41
UCEC	chr1	167017846	Missense_Mutation	NA	L310M	0.25	Maelstrom
UCEC	chr1	166989779	Nonsense_Mutation	NA	R59*	0.42
UCEC	chr1	167021752	Missense_Mutation	rs751586017	S401F	0.41
UCEC	chr1	167005392	Silent	NA	N280N	0.35
UCEC	chr1	167021892	3'UTR	novel		0.43
UCEC	chr1	167004266	Missense_Mutation	novel	H204Y	0.34	Maelstrom
UCEC	chr1	166989394	Silent	NA	F14F	0.3
UCEC	chr1	167021780	Missense_Mutation	novel	F410L	0.38
UCEC	chr1	166989475	Silent	NA	S41S	0.32
UCEC	chr1	166992757	Missense_Mutation	rs182472064	R133C	0.2	Maelstrom
UCEC	chr1	166989469	Nonsense_Mutation	novel	C39*	0.32
UCEC	chr1	167005351	Nonsense_Mutation	NA	R267*	0.33	Maelstrom
UCEC	chr1	166989443	Missense_Mutation	rs141032216	R31C	0.28
UCEC	chr1	166989937	Intron	novel		0.47
UCEC	chr1	167021954	3'UTR	novel		0.29
UCEC	chr1	166989391	Missense_Mutation	NA	F13L	0.57
UCEC	chr1	166989793	Silent	NA	A63A	0.2
UCEC	chr1	167004186	Missense_Mutation	rs532462606	S177Y	0.36	Maelstrom
UCEC	chr1	167005351	Nonsense_Mutation	NA	R267*	0.16	Maelstrom
UCEC	chr1	167016255	Silent	novel	F293F	0.44
UCEC	chr1	166992726	Silent	NA	S122S	0.58
UCEC	chr1	167016250	Missense_Mutation	novel	L292I	0.5	Maelstrom
UCEC	chr1	167017846	Silent	novel	L310L	0.32
UCEC	chr1	167005351	Nonsense_Mutation	NA	R267*	0.2	Maelstrom
UCEC	chr1	167016238	Nonsense_Mutation	NA	E288*	0.12	Maelstrom
UCEC	chr1	167021840	Missense_Mutation	NA	F430L	0.06
UCEC	chr1	166992709	Missense_Mutation	novel	F117V	0.27
UCEC	chr1	167021733	Missense_Mutation	rs762104760	R395C	0.34
UCEC	chr1	167005370	Missense_Mutation	NA	A273V	0.13	Maelstrom
UCEC	chr1	167021715	Missense_Mutation	rs202037854	R389W	0.18
UCEC	chr1	166989779	Nonsense_Mutation	NA	R59*	0.35
UCEC	chr1	167005363	Missense_Mutation	NA	D271N	0.46	Maelstrom
UCEC	chr1	167017843	Missense_Mutation	NA	S309A	0.41	Maelstrom
UCEC	chr1	167021758	Missense_Mutation	NA	S403Y	0.57
UCEC	chr1	167021977	3'UTR	novel		0.57
UCEC	chr1	166991453	Missense_Mutation	rs143708432	A101T	0.29
UCEC	chr1	167021111	Missense_Mutation	NA	F356L	0.28
UCEC	chr1	167005351	Nonsense_Mutation	NA	R267*	0.42	Maelstrom
UCEC	chr1	167021840	Missense_Mutation	NA	F430L	0.39
UCEC	chr1	167021715	Missense_Mutation	rs202037854	R389W	0.39
UCEC	chr1	166992791	Missense_Mutation	novel	Y144C	0.21	Maelstrom
UCEC	chr1	167005253	Splice_Region	novel		0.23
UCEC	chr1	167021711	Silent	rs146423777	S387S	0.14
UCEC	chr1	167021997	3'UTR	novel		0.29
UCEC	chr1	166989782	Missense_Mutation	rs199731527	E60K	0.26
UCEC	chr1	167021771	Silent	novel	I407I	0.3
UCEC	chr1	166989362	Missense_Mutation	novel	R4C	0.32
UCEC	chr1	166989810	Missense_Mutation	rs775977856	P69L	0.36
UCS	chr1	166992782	Missense_Mutation	novel	C141Y	0.22	Maelstrom
UCS	chr1	167005324	Missense_Mutation	NA	L258I	0.43	Maelstrom
UCS	chr1	167016251	Missense_Mutation	novel	L292P	0.07	Maelstrom
UCS	chr1	167021780	Missense_Mutation	novel	F410L	0.41

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
DLBC	DEL	0.0208	0.0017831
ESCA	AMP	0.413	0.0022446
KIRC	AMP	0.089	0.059566
PAAD	AMP	0.2228	0.085665
SKCM	AMP	0.4877	9.6912e-06
TGCT	AMP	0.3333	0.088103
THCA	AMP	0.0501	0.075436

Survival Analysis

Cancer	P-value	Q-value
THYM	0.028	Kaplan-Meier Survival Analysis
KIRC	0.0013	Kaplan-Meier Survival Analysis
SARC	0.014	Kaplan-Meier Survival Analysis
MESO	0.00018	Kaplan-Meier Survival Analysis
ACC	0.0058	Kaplan-Meier Survival Analysis
SKCM	0.001	Kaplan-Meier Survival Analysis
LIHC	0.0056	Kaplan-Meier Survival Analysis
DLBC	0.031	Kaplan-Meier Survival Analysis
LGG	0.00036	Kaplan-Meier Survival Analysis
LUAD	0.0014	Kaplan-Meier Survival Analysis

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotype

GWAS

PPI

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000143194 (Gene tree)
Gene ID: 84944
Gene Symbol: MAEL
Alias: FLJ14904|CT128|SPATA35
Full Name: maelstrom spermatogenic transposon silencer
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Plus strand
Length: 46,633 bases
Position: chr1:166,975,582-167,022,214
Accession: 25929
Summary: (Maelstrom Spermatogenic Transposon Silencer) is a Protein Coding gene. Among its related pathways are Mitotic Prophase and Gene Expression.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000402143	Maelstrom	PF13017.6	1.1e-42	1	1
ENSP00000482771	Maelstrom	PF13017.6	1.6e-42	1	1
ENSP00000356844	Maelstrom	PF13017.6	1.9e-42	1	1
ENSP00000356846	Maelstrom	PF13017.6	2.3e-42	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
19032786	Functional insight into Maelstrom in the germline piRNA pathway: a unique domain homologous to the DnaQ-H 3'-5' exonuclease, its lineage-specific expansion/loss and evolutionarily active site switch.	Biol Direct	2008 Nov 25	Zhang D	doi: 10.1186/1745-6150-3-48.
25778731	Metazoan Maelstrom is an RNA-binding protein that has evolved from an ancient nuclease active in protists.	RNA	2015 May	Chen KM	doi: 10.1261/rna.049437.114

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000367870	MAEL-201	1831	-	ENSP00000356844	403 (aa)	-	Q96JY0
ENST00000487826	MAEL-204	416	-	-	- (aa)	-	-
ENST00000367872	MAEL-202	1908	XM_006711583	ENSP00000356846	434 (aa)	XP_006711646	Q96JY0
ENST00000491055	MAEL-205	2355	-	-	- (aa)	-	-
ENST00000622874	MAEL-206	1700	XM_011510068	ENSP00000482771	378 (aa)	XP_011508370	E9JVC4
ENST00000447624	MAEL-203	1013	-	ENSP00000402143	316 (aa)	-	X6RGB1

Gene Model

Click here to download 's gene model file

Phenotype

ensgID	Trait	pValue	Pubmed ID
ENSG00000143194	Erythrocyte Indices	7.5220000E-006	-
ENSG00000143194	Erythrocyte Indices	5.8590000E-005	-
ENSG00000143194	Erythrocyte Indices	5.8550000E-006	-
ENSG00000143194	Erythrocyte Count	1.5470000E-005	-
ENSG00000143194	Erythrocyte Count	7.0390000E-005	-
ENSG00000143194	Erythrocyte Count	1.3720000E-005	-
ENSG00000143194	Platelet Function Tests	1.1100000E-006	-
ENSG00000143194	Platelet Function Tests	3.7800000E-007	-
ENSG00000143194	Platelet Function Tests	9.0700000E-008	-
ENSG00000143194	Platelet Function Tests	5.0100000E-006	-
ENSG00000143194	Platelet Function Tests	4.3800000E-006	-
ENSG00000143194	Platelet Function Tests	3.3593800E-005	-
ENSG00000143194	Platelet Function Tests	1.0387300E-005	-
ENSG00000143194	Astigmatism	3E-6	25367360

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000143194	rs6688613	1	166982632	T	Refractive astigmatism	25367360	[1.170-1.465]	1.309	HP_0000483

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000143194's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000143194	MAEL	100	90.618	ENSAMEG00000000018	MAEL	100	90.618	Ailuropoda_melanoleuca
ENSG00000143194	MAEL	97	53.959	ENSAPLG00000006696	MAEL	97	53.553	Anas_platyrhynchos
ENSG00000143194	MAEL	73	53.879	ENSACAG00000025602	-	100	49.822	Anolis_carolinensis
ENSG00000143194	MAEL	100	55.848	ENSACAG00000029327	-	84	55.025	Anolis_carolinensis
ENSG00000143194	MAEL	100	93.671	ENSANAG00000031520	MAEL	100	92.804	Aotus_nancymaae
ENSG00000143194	MAEL	100	89.401	ENSBTAG00000016550	MAEL	100	89.401	Bos_taurus
ENSG00000143194	MAEL	100	94.620	ENSCJAG00000017185	MAEL	100	94.293	Callithrix_jacchus
ENSG00000143194	MAEL	100	92.627	ENSCAFG00000015596	MAEL	100	93.103	Canis_familiaris
ENSG00000143194	MAEL	100	92.627	ENSCAFG00020022822	MAEL	100	92.627	Canis_lupus_dingo
ENSG00000143194	MAEL	100	92.627	ENSCHIG00000025356	MAEL	100	92.627	Capra_hircus
ENSG00000143194	MAEL	100	91.798	ENSTSYG00000003248	MAEL	100	89.425	Carlito_syrichta
ENSG00000143194	MAEL	95	65.217	ENSCAPG00000014130	MAEL	99	65.217	Cavia_aperea
ENSG00000143194	MAEL	100	80.403	ENSCPOG00000005046	MAEL	99	84.173	Cavia_porcellus
ENSG00000143194	MAEL	100	95.392	ENSCCAG00000033367	MAEL	100	95.392	Cebus_capucinus
ENSG00000143194	MAEL	100	98.734	ENSCATG00000036493	MAEL	100	97.767	Cercocebus_atys
ENSG00000143194	MAEL	97	85.714	ENSCLAG00000006862	MAEL	100	85.714	Chinchilla_lanigera
ENSG00000143194	MAEL	100	97.701	ENSCSAG00000010893	MAEL	100	97.701	Chlorocebus_sabaeus
ENSG00000143194	MAEL	100	68.433	ENSCHOG00000011901	MAEL	100	68.433	Choloepus_hoffmanni
ENSG00000143194	MAEL	100	64.265	ENSCPBG00000006089	MAEL	97	64.589	Chrysemys_picta_bellii
ENSG00000143194	MAEL	100	98.734	ENSCANG00000032047	MAEL	100	97.270	Colobus_angolensis_palliatus
ENSG00000143194	MAEL	100	90.323	ENSCGRG00001009188	Mael	100	90.323	Cricetulus_griseus_chok1gshd
ENSG00000143194	MAEL	100	90.323	ENSCGRG00000017037	Mael	100	90.323	Cricetulus_griseus_crigri
ENSG00000143194	MAEL	100	90.847	ENSDNOG00000016383	MAEL	100	90.847	Dasypus_novemcinctus
ENSG00000143194	MAEL	100	88.940	ENSDORG00000001149	Mael	100	88.940	Dipodomys_ordii
ENSG00000143194	MAEL	82	85.874	ENSETEG00000001331	MAEL	85	85.874	Echinops_telfairi
ENSG00000143194	MAEL	100	90.553	ENSEASG00005019126	MAEL	100	90.553	Equus_asinus_asinus
ENSG00000143194	MAEL	100	90.553	ENSECAG00000015077	MAEL	100	90.553	Equus_caballus
ENSG00000143194	MAEL	98	80.328	ENSEEUG00000014050	MAEL	100	80.328	Erinaceus_europaeus
ENSG00000143194	MAEL	100	94.620	ENSFCAG00000009285	MAEL	100	93.779	Felis_catus
ENSG00000143194	MAEL	100	50.575	ENSFALG00000001548	MAEL	98	50.372	Ficedula_albicollis
ENSG00000143194	MAEL	95	87.591	ENSFDAG00000012846	MAEL	100	87.591	Fukomys_damarensis
ENSG00000143194	MAEL	79	60.558	ENSGALG00000019211	MAEL	96	49.861	Gallus_gallus
ENSG00000143194	MAEL	100	61.960	ENSGAGG00000011274	MAEL	97	63.591	Gopherus_agassizii
ENSG00000143194	MAEL	100	99.367	ENSGGOG00000012560	MAEL	100	99.256	Gorilla_gorilla
ENSG00000143194	MAEL	95	87.591	ENSHGLG00000013438	MAEL	99	87.591	Heterocephalus_glaber_female
ENSG00000143194	MAEL	99	84.985	ENSHGLG00100014285	MAEL	99	81.156	Heterocephalus_glaber_male
ENSG00000143194	MAEL	100	93.088	ENSSTOG00000015434	MAEL	100	93.088	Ictidomys_tridecemlineatus
ENSG00000143194	MAEL	100	85.714	ENSJJAG00000011625	Mael	100	85.714	Jaculus_jaculus
ENSG00000143194	MAEL	100	51.437	ENSLACG00000008630	MAEL	99	53.086	Latimeria_chalumnae
ENSG00000143194	MAEL	100	89.954	ENSLAFG00000021470	MAEL	100	89.954	Loxodonta_africana
ENSG00000143194	MAEL	100	99.051	ENSMFAG00000040593	MAEL	100	98.511	Macaca_fascicularis
ENSG00000143194	MAEL	100	98.413	ENSMMUG00000023463	MAEL	100	98.413	Macaca_mulatta
ENSG00000143194	MAEL	100	99.051	ENSMNEG00000042870	MAEL	100	98.263	Macaca_nemestrina
ENSG00000143194	MAEL	100	98.734	ENSMLEG00000034260	MAEL	100	98.015	Mandrillus_leucophaeus
ENSG00000143194	MAEL	100	51.429	ENSMGAG00000014437	MAEL	95	50.000	Meleagris_gallopavo
ENSG00000143194	MAEL	100	89.862	ENSMAUG00000021599	Mael	100	89.862	Mesocricetus_auratus
ENSG00000143194	MAEL	100	95.886	ENSMICG00000034747	MAEL	100	94.931	Microcebus_murinus
ENSG00000143194	MAEL	100	88.249	ENSMOCG00000004042	Mael	100	87.558	Microtus_ochrogaster
ENSG00000143194	MAEL	100	78.082	ENSMODG00000002482	MAEL	100	78.082	Monodelphis_domestica
ENSG00000143194	MAEL	100	89.862	MGP_CAROLIEiJ_G0014814	Mael	100	89.862	Mus_caroli
ENSG00000143194	MAEL	100	89.862	ENSMUSG00000040629	Mael	100	89.862	Mus_musculus
ENSG00000143194	MAEL	100	89.862	MGP_PahariEiJ_G0028051	Mael	100	89.862	Mus_pahari
ENSG00000143194	MAEL	100	89.862	MGP_SPRETEiJ_G0015621	Mael	100	89.862	Mus_spretus
ENSG00000143194	MAEL	100	91.475	ENSMPUG00000015684	MAEL	100	91.475	Mustela_putorius_furo
ENSG00000143194	MAEL	100	87.414	ENSMLUG00000004095	MAEL	100	87.414	Myotis_lucifugus
ENSG00000143194	MAEL	99	89.277	ENSNGAG00000013179	Mael	99	89.277	Nannospalax_galili
ENSG00000143194	MAEL	100	98.418	ENSNLEG00000014771	MAEL	100	98.263	Nomascus_leucogenys
ENSG00000143194	MAEL	100	68.433	ENSMEUG00000001673	-	100	68.433	Notamacropus_eugenii
ENSG00000143194	MAEL	100	80.000	ENSOPRG00000005269	MAEL	100	80.000	Ochotona_princeps
ENSG00000143194	MAEL	95	84.951	ENSODEG00000002276	MAEL	99	84.951	Octodon_degus
ENSG00000143194	MAEL	79	65.882	ENSOANG00000003874	-	98	55.840	Ornithorhynchus_anatinus
ENSG00000143194	MAEL	100	89.885	ENSOCUG00000005848	MAEL	100	89.885	Oryctolagus_cuniculus
ENSG00000143194	MAEL	100	94.037	ENSOGAG00000007627	MAEL	100	94.037	Otolemur_garnettii
ENSG00000143194	MAEL	100	92.220	ENSOARG00000011888	MAEL	100	92.220	Ovis_aries
ENSG00000143194	MAEL	100	99.256	ENSPPAG00000042153	MAEL	100	99.256	Pan_paniscus
ENSG00000143194	MAEL	100	94.937	ENSPPRG00000003002	MAEL	100	93.548	Panthera_pardus
ENSG00000143194	MAEL	100	93.915	ENSPTIG00000011034	MAEL	93	93.878	Panthera_tigris_altaica
ENSG00000143194	MAEL	100	99.256	ENSPTRG00000001629	MAEL	100	99.256	Pan_troglodytes
ENSG00000143194	MAEL	100	98.734	ENSPANG00000000174	MAEL	100	98.263	Papio_anubis
ENSG00000143194	MAEL	100	60.684	ENSPSIG00000009813	MAEL	97	62.283	Pelodiscus_sinensis
ENSG00000143194	MAEL	74	77.778	ENSPCIG00000026830	-	96	77.778	Phascolarctos_cinereus
ENSG00000143194	MAEL	100	76.256	ENSPCIG00000030034	-	100	76.256	Phascolarctos_cinereus
ENSG00000143194	MAEL	100	98.677	ENSPPYG00000000555	MAEL	100	98.618	Pongo_abelii
ENSG00000143194	MAEL	95	72.145	ENSPCAG00000013028	MAEL	100	72.145	Procavia_capensis
ENSG00000143194	MAEL	100	94.620	ENSPCOG00000007295	MAEL	100	93.318	Propithecus_coquereli
ENSG00000143194	MAEL	100	85.591	ENSPVAG00000013294	MAEL	100	83.180	Pteropus_vampyrus
ENSG00000143194	MAEL	98	90.610	ENSRNOG00000003790	Mael	97	90.610	Rattus_norvegicus
ENSG00000143194	MAEL	100	99.051	ENSRBIG00000038763	MAEL	100	98.263	Rhinopithecus_bieti
ENSG00000143194	MAEL	100	99.051	ENSRROG00000039365	MAEL	100	98.263	Rhinopithecus_roxellana
ENSG00000143194	MAEL	100	94.937	ENSSBOG00000027193	MAEL	100	94.931	Saimiri_boliviensis_boliviensis
ENSG00000143194	MAEL	100	72.585	ENSSHAG00000018323	MAEL	100	73.418	Sarcophilus_harrisii
ENSG00000143194	MAEL	100	61.404	ENSSPUG00000018576	MAEL	96	60.101	Sphenodon_punctatus
ENSG00000143194	MAEL	100	91.705	ENSSSCG00000006316	MAEL	100	91.705	Sus_scrofa
ENSG00000143194	MAEL	100	48.547	ENSTGUG00000013511	MAEL	100	50.700	Taeniopygia_guttata
ENSG00000143194	MAEL	77	82.909	ENSTBEG00000003322	MAEL	85	75.068	Tupaia_belangeri
ENSG00000143194	MAEL	100	83.598	ENSTTRG00000006132	MAEL	100	84.670	Tursiops_truncatus
ENSG00000143194	MAEL	100	91.705	ENSUAMG00000018439	MAEL	100	91.705	Ursus_americanus
ENSG00000143194	MAEL	100	91.270	ENSUMAG00000016528	MAEL	99	91.408	Ursus_maritimus
ENSG00000143194	MAEL	84	91.880	ENSVPAG00000004937	MAEL	84	91.880	Vicugna_pacos
ENSG00000143194	MAEL	100	92.593	ENSVVUG00000026348	MAEL	100	92.593	Vulpes_vulpes
ENSG00000143194	MAEL	88	47.670	ENSXETG00000027834	mael	97	42.632	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0000785	chromatin	-	IEA	Component
GO:0000902	cell morphogenesis	-	IEA	Process
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	19274049.	ISM	Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	19274049.	NAS	Function
GO:0001741	XY body	-	IEA	Component
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	ISS	Component
GO:0005737	cytoplasm	-	ISS	Component
GO:0007129	synapsis	-	IEA	Process
GO:0007140	male meiotic nuclear division	21873635.	IBA	Process
GO:0007275	multicellular organism development	-	IEA	Process
GO:0007283	spermatogenesis	21873635.	IBA	Process
GO:0007283	spermatogenesis	-	ISS	Process
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	-	IEA	Process
GO:0009566	fertilization	-	IEA	Process
GO:0030154	cell differentiation	-	IEA	Process
GO:0030849	autosome	-	IEA	Component
GO:0031047	gene silencing by RNA	-	ISS	Process
GO:0033391	chromatoid body	-	IEA	Component
GO:0034587	piRNA metabolic process	21873635.	IBA	Process
GO:0034587	piRNA metabolic process	-	ISS	Process
GO:0043046	DNA methylation involved in gamete generation	-	ISS	Process
GO:0043066	negative regulation of apoptotic process	-	IEA	Process
GO:0043186	P granule	21873635.	IBA	Component
GO:0043186	P granule	-	ISS	Component
GO:0043565	sequence-specific DNA binding	21873635.	IBA	Function
GO:0045892	negative regulation of transcription, DNA-templated	21873635.	IBA	Process
GO:0046620	regulation of organ growth	-	IEA	Process
GO:0048471	perinuclear region of cytoplasm	-	IEA	Component
GO:0060964	regulation of gene silencing by miRNA	-	IEA	Process
GO:0071547	piP-body	-	ISS	Component

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