EuRBPDB

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TCGA tumor abbreviations
  • ACCAdrenocortical carcinoma
  • BLCABladder Urothelial Carcinoma
  • BRCABreast invasive carcinoma
  • CESCCervical squamous cell carcinoma and endocervical adenocarcinoma
  • CHOLCholangio carcinoma
  • COADColon adenocarcinoma
  • DLBCLymphoid Neoplasm Diffuse Large B-cell Lymphoma
  • ESCAEsophageal carcinoma
  • GBMGlioblastoma multiforme
  • HNSCHead and Neck squamous cell carcinoma
  • KICHKidney Chromophobe
  • KIRCKidney renal clear cell carcinoma
  • KIRPKidney renal papillary cell carcinoma
  • LAMLAcute Myeloid Leukemia
  • LGGBrain Lower Grade Glioma
  • LIHCLiver hepatocellular carcinoma
  • LUADLung adenocarcinoma
  • LUSCLung squamous cell carcinoma
  • MESOMesothelioma
  • OVOvarian serous cystadenocarcinoma
  • PAADPancreatic adenocarcinoma
  • PCPGPheochromocytoma and Paraganglioma
  • PRADProstate adenocarcinoma
  • READRectum adenocarcinoma
  • SARCSarcoma
  • SKCMSkin Cutaneous Melanoma
  • STADStomach adenocarcinoma
  • TGCTThyroid carcinoma
  • THCAThyroid carcinoma
  • THYMThymoma
  • UCECUterine Corpus Endometrial Carcinoma
  • UCSUterine Carcinosarcoma
  • UVMUveal Melanoma

Note: Click here to get the extension of tumor abbreviations.


  • Cancer Related Information
  • Basic Information

Differential Expression

Expression in 33 cancers

Mutations
CancerChrPosition Mutation TypedbSNPProtein-change Allele FreqRBD
BLCAchr1781197017SilentNAL565L0.56
BLCAchr1781199790Nonsense_MutationnovelQ318*0.19
BLCAchr1781194958SilentnovelL680L0.1
BLCAchr1781196746SilentnovelE621E1
BLCAchr1781192577Missense_MutationnovelE819K0.4
BLCAchr1781190997SilentNAL954L0.16
BLCAchr1781191038Missense_MutationNAE941Q0.2
BLCAchr1781190721Missense_MutationnovelE1012K0.53
BLCAchr1781191200Missense_Mutationrs577025986E923K0.24
BLCAchr1781193999Missense_Mutationrs763110139E753K0.63
BLCAchr1781191044Missense_MutationnovelE939K0.17
BLCAchr1781195880Missense_Mutationrs760427864Q660H0.19
BLCAchr1781202312Nonsense_MutationnovelS239*0.19
BRCAchr1781197039Missense_Mutationrs573786538A558V0.29
BRCAchr1781207152Silentrs766135433S120S0.25
BRCAchr1781198874Splice_Regionnovel0.13
BRCAchr1781194950Missense_MutationNAL683S0.15
BRCAchr1781194970Missense_MutationnovelE676D0.14
BRCAchr1781198951Missense_MutationNAG405S0.49
BRCAchr1781199441Nonsense_MutationNAQ378*0.51
BRCAchr1781191244Missense_MutationnovelE908G0.16
CESCchr1781194968Missense_MutationnovelI677N0.19
CESCchr1781191029Missense_MutationNAE944Q0.15
CESCchr1781198941Missense_MutationnovelD408G0.37
CESCchr17811896473'UTRnovel0.5
COADchr1781195943SilentNAE639E0.35
COADchr1781199733Nonsense_MutationnovelR337*0.44
COADchr1781191060Silentrs772025386Y933Y0.3
COADchr17811896753'UTRnovel0.14
COADchr1781202382Missense_MutationnovelA216T0.3
COADchr1781199538Missense_MutationnovelQ345H0.3
COADchr1781189976Splice_SitenovelX1039_splice0.14
COADchr1781197803Missense_MutationnovelT522M0.25
COADchr1781203580Silentrs375867858C181C0.38
COADchr1781191077Missense_Mutationrs753513530R928C0.24
COADchr1781200360Missense_Mutationrs575624973R292H0.35
COADchr1781189799SilentnovelQ1074Q0.21
COADchr1781189918SilentnovelH1058H0.07
COADchr1781191247Missense_MutationnovelL907P0.22
COADchr1781207197SilentNAS105S0.16
COADchr1781194951Missense_MutationnovelL683V0.12
COADchr1781208938Missense_Mutationrs144582854G88S0.58
COADchr1781192331Missense_Mutationrs771409290R873H0.38
COADchr1781191304Missense_MutationnovelL888P0.05
COADchr1781194873Nonsense_MutationnovelR709*0.14
COADchr1781208960Silentrs140020797T80T0.2
COADchr1781198168Missense_Mutationrs556177324V473M0.27
COADchr1781206796Missense_Mutationrs151144885R155W0.33
COADchr1781196825Missense_Mutationrs376678293A595V0.12
ESCAchr1781191200Missense_Mutationrs577025986E923K0.38
ESCAchr1781190975Missense_Mutationrs755773021E962K0.41
GBMchr1781190753Missense_Mutationrs537921227R1001H0.22
GBMchr1781202254Missense_MutationnovelE258D0.6
GBMchr1781196826Missense_MutationNAA595T0.59
GBMchr17811896683'UTRrs5781404200.49
GBMchr1781194926Missense_MutationnovelR691H0.28
HNSCchr1781189883Intronnovel0.09
HNSCchr1781208979Missense_MutationnovelR74I0.45
HNSCchr1781202270Missense_MutationnovelR253L0.22
HNSCchr1781191212Missense_MutationnovelE919K0.14
HNSCchr1781189826Silentrs748731729A1065A0.08
HNSCchr1781219948Missense_MutationnovelA37T0.33
KIRCchr1781195844Missense_MutationNAQ672H0.08
KIRCchr1781192753SilentNAL807L0.17
KIRCchr1781194874Frame_Shift_DelnovelV708Efs*100.22
KIRPchr1781191283Missense_MutationNAG895V0.19
KIRPchr1781192582Missense_MutationnovelE817G0.27
KIRPchr1781219880Splice_RegionnovelL59L0.14
LGGchr1781196754Nonsense_MutationnovelQ619*0.43
LGGchr1781199511SilentnovelA354A0.31
LIHCchr1781219899Missense_MutationNAE53V0.2
LIHCchr1781196993SilentNAV573V0.45
LIHCchr1781194068Nonsense_MutationnovelK730*0.05
LUADchr1781195907SilentnovelV651V0.22
LUADchr1781194881Missense_Mutationrs761833623V706A0.08
LUADchr1781192736Missense_MutationnovelR813K0.11
LUADchr1781203494Missense_MutationnovelN210S0.3
LUADchr1781199501Nonsense_MutationNAE358*0.29
LUADchr1781220023Missense_MutationnovelE12K0.31
LUADchr1781206832Missense_Mutationrs146148645R143W0.19
LUADchr1781191240SilentNAA909A0.16
LUADchr1781208988Missense_MutationNAN71S0.3
LUSCchr1781219968Missense_MutationnovelS30Y0.68
LUSCchr1781206830SilentnovelR143R0.31
LUSCchr1781191238Missense_MutationnovelD910V0.27
LUSCchr1781202326SilentnovelS234S0.17
LUSCchr17811897113'UTRnovel0.21
LUSCchr1781202306Missense_MutationnovelR241L0.2
LUSCchr1781190746Missense_MutationNAE1003D0.13
LUSCchr1781202314Missense_MutationnovelH238Q0.17
OVchr1781191275Missense_MutationnovelK898E0.16
OVchr1781199763Missense_MutationNAA327S0.45
OVchr1781189956Nonsense_MutationnovelA1045_R1046insAAF*Q*0.69
OVchr1781190987Missense_MutationNAL958V0.8
OVchr1781206860SilentNAP133P0.09
OVchr1781189839Missense_Mutationrs774586774A1061V0.5
PAADchr1781192337Missense_MutationnovelA871V0.2
PAADchr1781207233SilentnovelT93T0.18
SARCchr1781219962Missense_Mutationrs530864094R32H0.33
SARCchr1781189839Missense_Mutationrs774586774A1061V0.69
SARCchr1781199512Missense_MutationnovelA354E0.09
SARCchr1781191200Missense_Mutationrs577025986E923K0.27
SKCMchr1781207218SilentNAF98F0.35
SKCMchr1781194928SilentNAA690A0.83
SKCMchr1781219982SilentNAL25L0.26
SKCMchr1781203499SilentNAS208S0.35
SKCMchr1781219916SilentNAS47S0.54
SKCMchr1781196708Missense_MutationNAI634S0.32
SKCMchr1781199760Missense_MutationnovelR328W0.5
SKCMchr1781199761SilentnovelA327A0.5
SKCMchr1781207218SilentNAF98F0.19
SKCMchr1781198160SilentnovelP475P0.29
SKCMchr1781206780Missense_MutationnovelT160I0.33
SKCMchr1781196956Missense_MutationNAA586T0.21
SKCMchr1781192362Missense_MutationNAE863K0.23
SKCMchr1781192527SilentNAA835A0.38
SKCMchr1781190743Silentrs139538707F1004F0.35
SKCMchr1781207136Missense_MutationNAW126R0.18
SKCMchr1781203518Missense_MutationNAS202F0.33
SKCMchr1781197840Nonsense_MutationNAK510*0.55
SKCMchr1781189832Missense_MutationnovelK1063N0.26
SKCMchr1781208933SilentnovelS89S0.14
SKCMchr1781199773SilentnovelA323A0.83
SKCMchr1781197721SilentnovelS549S0.18
STADchr1781193990Missense_Mutationrs769897028R756W0.3
STADchr1781202270Missense_Mutationrs376964153R253Q0.16
STADchr1781199452Missense_Mutationrs373880117R374Q0.29
STADchr1781191025Missense_Mutationrs111464253R945Q0.26
STADchr1781197822Missense_Mutationrs144147050E516K0.38
STADchr1781206862Missense_MutationNAP133S0.44
STADchr1781207192Missense_MutationNAS107T0.57
STADchr1781194123SilentnovelL711L0.57
STADchr17811896743'UTRnovel0.26
STADchr1781191054Silentrs201159775A935A0.15
STADchr1781194078SilentnovelV726V0.36
STADchr1781195848Missense_Mutationrs368812421A671V0.4
STADchr1781203536Missense_Mutationrs750232619A196V0.19
STADchr1781199815SilentNAG309G0.2
STADchr1781199452Missense_Mutationrs373880117R374Q0.38
STADchr1781193999Missense_Mutationrs763110139E753K0.22
STADchr1781199812Missense_MutationNAE310D0.12
STADchr1781191004Missense_Mutationrs773523503S952L0.39
UCECchr1781194954Nonsense_MutationNAE682*0.29
UCECchr1781199829Missense_Mutationrs375208941R305W0.27
UCECchr1781199498Missense_Mutationrs763309058R359C0.32
UCECchr1781208939Silentrs148304893S87S0.48
UCECchr1781197005SilentnovelV569V0.22
UCECchr1781196957Missense_MutationnovelQ585H0.08
UCECchr1781198973Splice_SitenovelX398_splice0.19
UCECchr1781198119Missense_Mutationrs182537101S489N0.37
UCECchr1781199530Missense_MutationnovelA348D0.11
UCECchr1781207160Missense_MutationnovelA118T0.3
UCECchr1781198965Missense_MutationNAG400D0.33
UCECchr1781203545Missense_Mutationrs796803247S193L0.59
UCECchr1781198883Missense_MutationnovelR427S0.29
UCECchr17811897023'UTRnovel0.31
UCECchr1781190925Silentrs755756902A978A0.23
UCECchr1781195847Silentrs367990055A671A0.58
UCECchr1781190914Missense_Mutationrs780940898A982V0.14
UCECchr1781192589Missense_Mutationrs746435622R815W0.43
UCECchr1781189942Silentrs775549243A1050A0.35
UCECchr1781191006SilentnovelC951C0.46
UCECchr1781196757Missense_MutationnovelR618W0.1
UCECchr1781203580Silentrs375867858C181C0.33
UCECchr1781192566SilentnovelR822R0.32
UCECchr1781193948Missense_MutationnovelE770K0.6
UCECchr1781194927Missense_Mutationrs143625194R691C0.44
UCECchr1781206747Missense_MutationnovelN171T0.3
UCECchr1781195916Silentrs368017972C648C0.31
UCECchr1781196802Missense_Mutationrs150527009R603W0.34
UCECchr1781199451Silentrs756128984R374R0.23
UCECchr1781198973Splice_SiteNAX398_splice0.28
UCECchr1781189883Intronnovel0.57
UCECchr1781189942Silentrs775549243A1050A0.14
UCECchr1781189831Missense_Mutationrs371210650R1064W0.36
UCECchr1781195871Silentrs138282299T663T0.43
UCECchr1781189920Missense_MutationnovelH1058Y0.35
UCECchr1781195863Missense_MutationnovelV666A0.51
UCSchr1781206797Silentrs781565082P154P0.13
UVMchr1781192811Missense_Mutationrs754140951A788V0.37
UVMchr1781219965Missense_Mutationrs372370793R31Q0.47

Copy Number Variations (CNVs)
CancerTypeFreq Q-value
BLCAAMP0.38970.00012456
KIRPAMP0.67010.14801
LGGAMP0.06431.52e-05
LIHCAMP0.36221.3152e-14
SARCAMP0.21790.032181
SKCMAMP0.28617.0388e-08
THCADEL0.0020.221
UVMAMP0.16250.054583

Survival Analysis
CancerP-value Q-value
KIRC0.00011

Kaplan-Meier Survival Analysis

STAD0.027

Kaplan-Meier Survival Analysis

SARC0.0025

Kaplan-Meier Survival Analysis

MESO0.0018

Kaplan-Meier Survival Analysis

ACC0.00012

Kaplan-Meier Survival Analysis

SKCM0.015

Kaplan-Meier Survival Analysis

BRCA0.038

Kaplan-Meier Survival Analysis

KIRP0.023

Kaplan-Meier Survival Analysis

PAAD0.00019

Kaplan-Meier Survival Analysis

BLCA0.028

Kaplan-Meier Survival Analysis

CESC0.0056

Kaplan-Meier Survival Analysis

LAML0.039

Kaplan-Meier Survival Analysis

LIHC0.0001

Kaplan-Meier Survival Analysis

Drugs

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Eesembl ID



Cell lines and drugs in GSE70138 or GSE92742

  • Description
  • RBPome
  • Expression
  • Transcripts
  • Gene Model
  • Phenotypes
  • GWAS
  • PPI
  • Gene Ontology
Description
Ensembl ID
ENSG00000141577 (Gene tree)
Gene ID
22994
Gene Symbol
CEP131
Alias
AZ1|KIAA1118|AZI1
Full Name
centrosomal protein 131
Gene Type
protein_coding
Species
Homo_sapiens
Status
putative
Strand
Minus strand
Length
33,407 bases
Position
chr17:81,189,593-81,222,999
Accession
29511
RBP type
non-canonical RBP
Summary
(Centrosomal Protein 131) is a Protein Coding gene. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity.
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & U2OS2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000570482CEP131-204613--- (aa)--
ENST00000269392CEP131-2013673XM_011524547ENSP000002693921083 (aa)XP_011522849Q9UPN4
ENST00000374782CEP131-2023505-ENSP000003639141044 (aa)-Q9UPN4
ENST00000571292CEP131-206619-ENSP00000460098206 (aa)-I3L316
ENST00000570817CEP131-2051160-ENSP00000461374307 (aa)-I3L4M5
ENST00000575907CEP131-2083444XM_011524552ENSP000004597331047 (aa)XP_011522854I3L2J8
ENST00000450824CEP131-2033543XM_011524548ENSP000003935831080 (aa)XP_011522850Q9UPN4
ENST00000573053CEP131-2071747-ENSP00000460006524 (aa)-I3L2X7
Gene Model
Click here to download ENSG00000141577's gene model file
Phenotypes
ensgIDTraitpValuePubmed ID
ENSG00000141577Frontotemporal Dementia7E-626154020
ENSG00000141577Frontotemporal Dementia8E-726154020
ENSG00000141577Frontotemporal Dementia7E-626154020
ENSG00000141577Frontotemporal Dementia8E-726154020
ENSG00000141577Frontotemporal Dementia7E-626154020
ENSG00000141577Frontotemporal Dementia8E-726154020
ENSG00000141577Frontotemporal Dementia8E-726154020
ENSG00000141577Frontotemporal Dementia4E-626154020
ENSG00000141577Frontotemporal Dementia7E-626154020
ENSG00000141577Frontotemporal Dementia8E-726154020
ENSG00000141577Frontotemporal Dementia7E-626154020
ENSG00000141577Frontotemporal Dementia4E-626154020
ENSG00000141577Frontotemporal Dementia7E-626154020
ENSG00000141577Frontotemporal Dementia7E-626154020
ENSG00000141577Frontotemporal Dementia7E-626154020
ENSG00000141577Frontotemporal Dementia4E-626154020
ENSG00000141577Immunoglobulins4E-723382691
ENSG00000141577Frontotemporal Dementia4E-626154020
ENSG00000141577Frontotemporal Dementia1E-726154020
ENSG00000141577Frontotemporal Dementia4E-626154020
ENSG00000141577Frontotemporal Dementia7E-626154020
GWAS
ensgIDSNPChromosomePositionSNP-risk TraitPubmedID95% CIOr or BEAT EFO ID
ENSG00000141577rs9061751781199662TFrontotemporal dementia26154020[1.33-1.87]1.58Orphanet_282
ENSG00000141577rs22799131781194468CIgG glycosylation23382691[0.097-0.219] unit increase0.1579EFO_0005193
ENSG00000141577rs93196171781218646CIgG galactosylation phenotypes (multivariate analysis)28878392EFO_0008425
ENSG00000141577rs93196171781218646CIgG N-glycosylation phenotypes (multivariate analysis)28878392EFO_0005193
ENSG00000141577rs80712101781211018?Red blood cell count30595370EFO_0004305
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000141577's network

* RBP PPI network refers to all genes directly bind to RBP
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0000086G2/M transition of mitotic cell cycle-TASProcess
GO:0001669acrosomal vesicle-IEAComponent
GO:0005515protein binding22797915.24089205.24407287.24550735.24816561.26297806.26638075.IPIFunction
GO:0005813centrosome21399614.22797915.24550735.IDAComponent
GO:0005813centrosome14654843.IDAComponent
GO:0005815microtubule organizing center-IDAComponent
GO:0005829cytosol-TASComponent
GO:0007275multicellular organism development-IEAProcess
GO:0007283spermatogenesis-IEAProcess
GO:0008284positive regulation of cell proliferation22797915.IMPProcess
GO:0010389regulation of G2/M transition of mitotic cell cycle-TASProcess
GO:0010824regulation of centrosome duplication21873635.IBAProcess
GO:0010824regulation of centrosome duplication22797915.IMPProcess
GO:0015630microtubule cytoskeleton-IDAComponent
GO:0030154cell differentiation-IEAProcess
GO:0034451centriolar satellite21873635.IBAComponent
GO:0034451centriolar satellite22797915.24550735.26297806.IDAComponent
GO:0035735intraciliary transport involved in cilium assembly24550735.IMPProcess
GO:0035869ciliary transition zone24415959.IDAComponent
GO:0042803protein homodimerization activity24550735.IDAFunction
GO:0043231intracellular membrane-bounded organelle-IDAComponent
GO:0044877protein-containing complex binding24550735.IDAFunction
GO:0045171intercellular bridge-IDAComponent
GO:0060271cilium assembly21873635.IBAProcess
GO:0071539protein localization to centrosome26297806.IMPProcess
GO:0090316positive regulation of intracellular protein transport24550735.IMPProcess
GO:0097711ciliary basal body-plasma membrane docking-TASProcess
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