EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
26211588	Increased expression of proline-, glutamic acid- and leucine-rich protein PELP1 in non-small cell lung cancer.	Biomed Pharmacother	2015 Jul	Sowikowski BK	doi: 10.1016/j.biopha.2015.05.015
23975430	Significance of PELP1/HDAC2/miR-200 regulatory network in EMT and metastasis of breast cancer.	Oncogene	2014 Jul 10	Roy SS	doi: 10.1038/onc.2013.332
18079323	Modulation of in situ estrogen synthesis by proline-, glutamic acid-, and leucine-rich protein-1: potential estrogen receptor autocrine signaling loop in breast cancer cells.	Mol Endocrinol	2008 Mar	Rajhans R	-
19800002	Regulation of aromatase induction by nuclear receptor coregulator PELP1.	J Steroid Biochem Mol Biol	2010 Feb 28	Vadlamudi RK	doi: 10.1016/j.jsbmb.2009.09.009
19495959	The prognostic significance of PELP1 expression in invasive breast cancer with emphasis on the ER-positive luminal-like subtype.	Breast Cancer Res Treat	2010 Apr	Habashy HO	doi: 10.1007/s10549-009-0419-9
24627205	The pattern of proline, glutamic acid, and leucine-rich protein 1 expression in Chinese women with primary breast cancer.	Int J Biol Markers	2014 Mar 24	Zhang Y	doi: 10.5301/jbm.5000078.
17128415	Emerging significance of ER-coregulator PELP1/MNAR in cancer.	Histol Histopathol	2007 Jan	Nair S	doi: 10.14670/HH-22.91.
15374949	Potential role of a novel transcriptional coactivator PELP1 in histone H1 displacement in cancer cells.	Cancer Res	2004 Sep 15	Nair SS	-
22992812	PELP1/MNAR suppression inhibits proliferation and metastasis of endometrial carcinoma cells.	Oncol Rep	2012 Dec	Wan J	doi: 10.3892/or.2012.2038
22086908	Significance of PELP1 in ER-negative breast cancer metastasis.	Mol Cancer Res	2012 Jan	Roy S	doi: 10.1158/1541-7786.MCR-11-0456
17545633	Oncogenic potential of the nuclear receptor coregulator proline-, glutamic acid-, leucine-rich protein 1/modulator of the nongenomic actions of the estrogen receptor.	Cancer Res	2007 Jun 1	Rajhans R	-
24967003	PELP1 suppression inhibits colorectal cancer through c-Src downregulation.	Oxid Med Cell Longev	2014	Ning Z	doi: 10.1155/2014/193523
17804729	Identifying the estrogen receptor coactivator PELP1 in autophagosomes.	Cancer Res	2007 Sep 1	Ohshiro K	-
26472563	Prognostic significance of proline, glutamic acid, leucine rich protein 1 (PELP1) in triple-negative breast cancer: a retrospective study on 129 cases.	BMC Cancer	2015 Oct 15	Zhang Y	doi: 10.1186/s12885-015-1694-y.
17192406	Proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor enhances androgen receptor functions through LIM-only coactivator, four-and-a-half LIM-only protein 2.	Mol Endocrinol	2007 Mar	Nair SS	-
22403175	Central role for PELP1 in nonandrogenic activation of the androgen receptor in prostate cancer.	Mol Endocrinol	2012 Apr	Yang L	doi: 10.1210/me.2011-1101
25788226	Novel role of PELP1 in regulating chemotherapy response in mutant p53-expressing triple negative breast cancer cells.	Breast Cancer Res Treat	2015 Apr	Krishnan SR	doi: 10.1007/s10549-015-3339-x
27881676	Cytoplasmic Localization of Proline, Glutamic Acid, Leucine-rich Protein 1 (PELP1) Induces Breast Epithelial Cell Migration through Up-regulation of Inhibitor of ??B Kinase and Inflammatory Cross-talk with Macrophages.	J Biol Chem	2017 Jan 6	Girard BJ	doi: 10.1074/jbc.M116.739847

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr17	4674651	Frame_Shift_Ins	novel	*S481Efs3**	0.17
BLCA	chr17	4674949	Missense_Mutation	novel	R428W	0.23
BLCA	chr17	4672937	Missense_Mutation	novel	S685L	0.4
BLCA	chr17	4671522	Missense_Mutation	rs752579746	D1104N	0.2
BLCA	chr17	4674640	Silent	rs757051159	G484G	0.71
BLCA	chr17	4671783	Missense_Mutation	novel	E1070Q	0.29
BRCA	chr17	4675139	Missense_Mutation	NA	V405A	0.57
BRCA	chr17	4682507	Missense_Mutation	novel	L213F	0.33
BRCA	chr17	4673252	Missense_Mutation	NA	E615Q	0.34
BRCA	chr17	4676771	Missense_Mutation	novel	L228F	0.11
BRCA	chr17	4672986	Missense_Mutation	NA	G669C	0.58
BRCA	chr17	4672305	Nonsense_Mutation	novel	E896*	0.1
BRCA	chr17	4691401	Silent	NA	A97A	0.58
BRCA	chr17	4673284	Missense_Mutation	NA	A604V	0.67
CESC	chr17	4672149	Missense_Mutation	novel	E948Q	0.52
CESC	chr17	4672759	Silent	NA	G744G	0.33
CESC	chr17	4672948	Silent	NA	G681G	0.42
CESC	chr17	4674922	Silent	novel	L437L	0.09
CESC	chr17	4675337	Missense_Mutation	novel	R365Q	0.5
COAD	chr17	4672756	Silent	novel	T745T	0.41
COAD	chr17	4690991	Missense_Mutation	novel	F106S	0.16	RIX1
COAD	chr17	4690923	Frame_Shift_Ins	novel	*V129Sfs28**	0.31	RIX1
COAD	chr17	4673017	Silent	rs750844787	S658S	0.53
COAD	chr17	4672457	Missense_Mutation	rs753210674	P845L	0.87
COAD	chr17	4671877	Missense_Mutation	rs775710694	E1038D	0.29
COAD	chr17	4682847	Missense_Mutation	novel	H176N	0.07
COAD	chr17	4673014	Silent	NA	P659P	0.22
COAD	chr17	4675357	Silent	NA	L358L	0.27
COAD	chr17	4672775	Missense_Mutation	NA	I739T	0.24
COAD	chr17	4672988	Missense_Mutation	rs766876710	P668L	0.18
COAD	chr17	4672261	Missense_Mutation	NA	F910L	0.39
COAD	chr17	4672150	Silent	rs112480622	E947E	0.23
COAD	chr17	4676068	Silent	rs781244089	S316S	0.16
COAD	chr17	4676424	Missense_Mutation	NA	Q262H	0.18
COAD	chr17	4672615	Silent	rs116554252	P792P	0.26
COAD	chr17	4672177	Missense_Mutation	NA	E938D	0.3
COAD	chr17	4672953	Missense_Mutation	NA	A680P	0.3
COAD	chr17	4674614	Missense_Mutation	NA	A493V	0.53
COAD	chr17	4672601	Missense_Mutation	NA	P797L	0.95
COAD	chr17	4676081	Missense_Mutation	rs373744745	R312Q	0.18
COAD	chr17	4672033	Silent	NA	L986L	0.2
COAD	chr17	4674948	Missense_Mutation	NA	R428Q	0.24
COAD	chr17	4673383	Missense_Mutation	rs750151202	T571M	0.29
ESCA	chr17	4674897	Missense_Mutation	rs765738529	S445L	0.1
ESCA	chr17	4690916	Missense_Mutation	novel	W131S	0.16	RIX1
GBM	chr17	4672135	Missense_Mutation	novel	E952D	0.11
GBM	chr17	4671760	Missense_Mutation	novel	Q1077H	0.21
GBM	chr17	4690895	Missense_Mutation	novel	V138A	0.39	RIX1
GBM	chr17	4675315	Silent	novel	I372I	0.18
GBM	chr17	4674513	Nonsense_Mutation	novel	R527*	0.08
GBM	chr17	4675281	Frame_Shift_Del	novel	*I384Sfs14**	0.08
HNSC	chr17	4673076	Nonsense_Mutation	novel	Q639*	0.34
HNSC	chr17	4704038	Missense_Mutation	novel	S25L	0.14
HNSC	chr17	4704145	5'Flank	novel		0.24
HNSC	chr17	4675129	Silent	novel	S408S	0.11
HNSC	chr17	4690919	Missense_Mutation	novel	S130C	0.15	RIX1
KIRC	chr17	4674620	Frame_Shift_Del	novel	*P491Lfs7**	0.28
KIRP	chr17	4671787	Silent	NA	E1068E	0.18
LGG	chr17	4675162	Silent	NA	L397L	0.2
LGG	chr17	4676438	Missense_Mutation	rs757402798	E258K	0.4
LGG	chr17	4676438	Missense_Mutation	rs757402798	E258K	0.45
LIHC	chr17	4672809	Missense_Mutation	rs770325846	E728K	0.4
LIHC	chr17	4673109	Missense_Mutation	NA	A628T	0.33
LIHC	chr17	4676771	Missense_Mutation	novel	L228F	0.15
LIHC	chr17	4682549	Missense_Mutation	NA	M199V	0.07
LIHC	chr17	4676057	Missense_Mutation	rs747418545	R320H	0.07
LUAD	chr17	4703946	Missense_Mutation	novel	V56L	0.17
LUAD	chr17	4671392	3'UTR	novel		0.18
LUAD	chr17	4704114	5'UTR	novel		0.32
LUAD	chr17	4672785	Missense_Mutation	novel	E736K	0.36
LUAD	chr17	4691394	Missense_Mutation	rs760001532	S100C	0.83	RIX1
LUAD	chr17	4673652	Missense_Mutation	NA	M535I	0.61
LUAD	chr17	4672863	Missense_Mutation	novel	G710C	0.53
LUAD	chr17	4671712	Missense_Mutation	novel	E1093D	0.32
LUAD	chr17	4671953	Missense_Mutation	novel	G1013A	0.6
LUAD	chr17	4675814	Missense_Mutation	novel	V351L	0.5
LUSC	chr17	4672644	Missense_Mutation	novel	D783N	0.57
LUSC	chr17	4671981	Missense_Mutation	NA	G1004W	0.82
LUSC	chr17	4672774	Silent	rs758163168	I739I	0.29
LUSC	chr17	4672580	Nonsense_Mutation	novel	S804*	0.19
LUSC	chr17	4674642	Missense_Mutation	novel	G484W	0.2
OV	chr17	4675316	Missense_Mutation	novel	I372N	0.14
OV	chr17	4674612	Missense_Mutation	NA	P494T	0.71
OV	chr17	4682941	Silent	rs377442278	P144P	0.47
PRAD	chr17	4671950	Missense_Mutation	rs368789821	T1014M	0.12
READ	chr17	4673366	Missense_Mutation	rs767650542	R577C	0.4
READ	chr17	4683107	Intron	novel		0.43
SARC	chr17	4672450	Silent	rs570217183	P847P	0.22
SARC	chr17	4675538	Intron	novel		0.08
SKCM	chr17	4674872	Silent	NA	A453A	0.58
SKCM	chr17	4671484	Silent	novel	P1116P	0.2
SKCM	chr17	4673014	Silent	NA	P659P	0.49
SKCM	chr17	4673015	Missense_Mutation	novel	P659L	0.49
SKCM	chr17	4673035	Silent	NA	P652P	0.45
SKCM	chr17	4676500	Missense_Mutation	NA	C237F	0.18
SKCM	chr17	4674555	Missense_Mutation	NA	G513R	0.27
SKCM	chr17	4674556	Missense_Mutation	novel	K512N	0.27
SKCM	chr17	4672002	Missense_Mutation	NA	P997S	1
SKCM	chr17	4682855	Missense_Mutation	NA	S173F	0.36
SKCM	chr17	4673291	Silent	novel	L602L	0.44
SKCM	chr17	4674573	Missense_Mutation	NA	P507S	0.25
SKCM	chr17	4703865	Nonsense_Mutation	novel	Q83*	0.36	RIX1
SKCM	chr17	4674652	Silent	novel	G480G	0.5
SKCM	chr17	4672553	Missense_Mutation	novel	P813L	0.36
SKCM	chr17	4672016	Missense_Mutation	NA	P992L	0.6
SKCM	chr17	4673661	Silent	NA	T532T	0.17
SKCM	chr17	4682525	Missense_Mutation	novel	P207S	0.7
SKCM	chr17	4673014	Silent	NA	P659P	0.28
SKCM	chr17	4674814	Missense_Mutation	NA	L473F	0.27
SKCM	chr17	4672818	Missense_Mutation	NA	P725S	0.28
SKCM	chr17	4671841	Silent	NA	P1050P	0.31
SKCM	chr17	4673042	Missense_Mutation	NA	P650L	0.2
SKCM	chr17	4674660	Missense_Mutation	NA	P478S	0.74
SKCM	chr17	4674868	Missense_Mutation	NA	G455R	0.85
SKCM	chr17	4674653	Missense_Mutation	rs764771503	G480E	0.39
SKCM	chr17	4674654	Missense_Mutation	rs750166392	G480R	0.39
SKCM	chr17	4672494	Missense_Mutation	novel	P833S	0.86
SKCM	chr17	4672027	Silent	NA	P988P	0.6
SKCM	chr17	4672832	In_Frame_Del	novel	G715_P720del	0.3
SKCM	chr17	4704026	Missense_Mutation	NA	S29L	0.38
SKCM	chr17	4673089	Silent	novel	R634R	0.67
SKCM	chr17	4672948	Silent	NA	G681G	0.34
SKCM	chr17	4675185	Missense_Mutation	rs762432194	R390W	0.38
SKCM	chr17	4676457	Silent	novel	S251S	0.4
SKCM	chr17	4672995	Missense_Mutation	NA	H666Y	0.45
STAD	chr17	4691399	Missense_Mutation	rs377024175	R98H	0.12	RIX1
STAD	chr17	4690921	Silent	NA	V129V	0.22
STAD	chr17	4682544	Missense_Mutation	NA	K200N	0.32
STAD	chr17	4672999	Silent	NA	P664P	0.14
STAD	chr17	4672901	Missense_Mutation	rs558960670	S697L	0.5
STAD	chr17	4675154	Missense_Mutation	rs749311186	R400H	0.42
STAD	chr17	4671895	Silent	novel	P1032P	0.55
STAD	chr17	4704135	5'Flank	novel		0.33
STAD	chr17	4672962	Missense_Mutation	novel	M677V	0.23
STAD	chr17	4671901	Silent	rs370860807	A1030A	0.35
STAD	chr17	4671692	Frame_Shift_Del	novel	*K1100Rfs43**	0.63
STAD	chr17	4672022	Missense_Mutation	novel	E990V	0.29
TGCT	chr17	4671518	Missense_Mutation	novel	T1105K	0.09
THCA	chr17	4691432	Frame_Shift_Ins	novel	*A87Dfs10**	0.06	RIX1
THCA	chr17	4691433	Missense_Mutation	novel	A87P	0.06	RIX1
THYM	chr17	4672716	Frame_Shift_Ins	rs770510786	*R759Efs11**	0.43
UCEC	chr17	4674524	Missense_Mutation	rs776758532	A523V	0.35
UCEC	chr17	4673317	Missense_Mutation	rs373356661	R593H	0.16
UCEC	chr17	4671923	Missense_Mutation	novel	A1023D	0.29
UCEC	chr17	4676041	Missense_Mutation	NA	M325I	0.23
UCEC	chr17	4676811	Missense_Mutation	NA	G215D	0.17
UCEC	chr17	4673374	Missense_Mutation	NA	R574H	0.33
UCEC	chr17	4673657	Missense_Mutation	novel	L534I	0.24
UCEC	chr17	4671502	Silent	rs750465811	A1110A	0.42
UCEC	chr17	4674535	Silent	rs372215978	S519S	0.39
UCEC	chr17	4671709	Silent	rs372694155	A1094A	0.2
UCEC	chr17	4676361	Silent	novel	E283E	0.58
UCEC	chr17	4674572	Missense_Mutation	rs199877885	P507L	0.47
UCEC	chr17	4671921	Missense_Mutation	NA	P1024S	0.32
UCEC	chr17	4672901	Missense_Mutation	rs558960670	S697L	0.29
UCEC	chr17	4672153	Missense_Mutation	novel	E946D	0.4
UCEC	chr17	4674947	Silent	novel	R428R	0.42
UCEC	chr17	4704074	Missense_Mutation	novel	S13C	0.27
UCEC	chr17	4704075	Missense_Mutation	novel	S13A	0.27
UCEC	chr17	4671707	Missense_Mutation	novel	E1095A	0.21
UCEC	chr17	4672282	Silent	novel	E903E	0.05
UCEC	chr17	4671915	Missense_Mutation	novel	L1026M	0.41
UCEC	chr17	4673453	Silent	novel	L548L	0.36
UCEC	chr17	4674651	Frame_Shift_Ins	novel	*S481Efs3**	0.33
UCEC	chr17	4671939	Missense_Mutation	NA	R1018C	0.54
UCEC	chr17	4675186	Silent	novel	S389S	0.38
UCEC	chr17	4676791	Frame_Shift_Ins	novel	*L222Sfs3**	0.45
UCEC	chr17	4673097	Missense_Mutation	novel	H632N	0.43
UCEC	chr17	4675090	Missense_Mutation	NA	E421D	0.33
UCEC	chr17	4672237	Missense_Mutation	novel	E918D	0.53
UCEC	chr17	4676787	Missense_Mutation	novel	S223Y	0.23
UCEC	chr17	4674942	Missense_Mutation	NA	K430M	0.31
UCEC	chr17	4690991	Missense_Mutation	NA	F106C	0.39	RIX1
UCEC	chr17	4676064	Missense_Mutation	novel	L318M	0.15
UCEC	chr17	4675155	Missense_Mutation	novel	R400C	0.34
UCS	chr17	4672901	Missense_Mutation	rs558960670	S697L	0.42

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
DLBC	DEL	0.2083	0.18166
LAML	DEL	0.0733	0.12511
LIHC	DEL	0.5486	3.9592e-10
THCA	DEL	0.016	0.221

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.014	Kaplan-Meier Survival Analysis
SARC	0.007	Kaplan-Meier Survival Analysis
ACC	0.013	Kaplan-Meier Survival Analysis
SKCM	0.046	Kaplan-Meier Survival Analysis
PRAD	0.029	Kaplan-Meier Survival Analysis
COAD	0.04	Kaplan-Meier Survival Analysis
PAAD	0.00011	Kaplan-Meier Survival Analysis
CESC	0.029	Kaplan-Meier Survival Analysis
KICH	0.023	Kaplan-Meier Survival Analysis
LIHC	0.0016	Kaplan-Meier Survival Analysis
LGG	0.0038	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotype

GWAS

PPI

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000141456 (Gene tree)
Gene ID: 27043
Gene Symbol: PELP1
Alias: MNAR
Full Name: proline, glutamate and leucine rich protein 1
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Minus strand
Length: 34,564 bases
Position: chr17:4,669,774-4,704,337
Accession: 30134
Summary: This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. This gene may be involved in the progression of several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000460959	RIX1	PF08167.12	2.3e-25	1	1
ENSP00000461625	RIX1	PF08167.12	1.8e-24	1	1
ENSP00000301396	RIX1	PF08167.12	1.9e-24	1	1
ENSP00000460300	RIX1	PF08167.12	1.9e-24	1	1
ENSP00000461419	RIX1	PF08167.12	3.9e-10	1	1
ENSP00000416231	RIX1	PF08167.12	1.6e-08	1	1
ENSP00000458985	RIX1	PF08167.12	2.5e-06	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000571170	PELP1-206	555	-	-	- (aa)	-	-
ENST00000571347	PELP1-207	708	-	-	- (aa)	-	-
ENST00000573242	PELP1-209	574	-	-	- (aa)	-	-
ENST00000436683	PELP1-202	3524	-	ENSP00000416231	906 (aa)	-	E7EV54
ENST00000575329	PELP1-214	3280	-	ENSP00000461380	156 (aa)	-	I3L4M7
ENST00000570571	PELP1-204	902	-	ENSP00000460959	301 (aa)	-	I3L445
ENST00000570823	PELP1-205	484	-	-	- (aa)	-	-
ENST00000572293	PELP1-208	5272	-	ENSP00000460300	1180 (aa)	-	C9JFV4
ENST00000575534	PELP1-215	601	-	-	- (aa)	-	-
ENST00000573506	PELP1-210	415	-	-	- (aa)	-	-
ENST00000573523	PELP1-211	3878	-	-	- (aa)	-	-
ENST00000575101	PELP1-213	442	-	ENSP00000458985	148 (aa)	-	I3L1P4
ENST00000570387	PELP1-203	567	-	ENSP00000461419	99 (aa)	-	I3L4P1
ENST00000574876	PELP1-212	3465	-	ENSP00000461625	1130 (aa)	-	Q8IZL8
ENST00000301396	PELP1-201	3673	-	ENSP00000301396	1180 (aa)	-	C9JFV4

Gene Model

Click here to download 's gene model file

Phenotype

ensgID	Trait	pValue	Pubmed ID
ENSG00000141456	Alcoholism	2.01E-05	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000141456	rs9901392	17	4701541	?	Eosinophil counts	29403010	[0.031-0.064] unit increase novel	0.04745	EFO_0004842

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000141456's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000141456	PELP1	100	100.000	ENSANAG00000034054	PELP1	100	96.306	Aotus_nancymaae
ENSG00000141456	PELP1	100	94.949	ENSBTAG00000018315	PELP1	74	88.093	Bos_taurus
ENSG00000141456	PELP1	100	98.990	ENSCJAG00000012265	PELP1	94	96.305	Callithrix_jacchus
ENSG00000141456	PELP1	100	97.980	ENSCAFG00000015914	PELP1	79	91.085	Canis_familiaris
ENSG00000141456	PELP1	100	97.980	ENSCAFG00020011106	PELP1	77	92.870	Canis_lupus_dingo
ENSG00000141456	PELP1	100	93.939	ENSCHIG00000026719	PELP1	79	88.501	Capra_hircus
ENSG00000141456	PELP1	100	91.919	ENSCAPG00000005521	PELP1	76	90.553	Cavia_aperea
ENSG00000141456	PELP1	100	91.919	ENSCPOG00000000208	PELP1	79	89.621	Cavia_porcellus
ENSG00000141456	PELP1	100	100.000	ENSCCAG00000037754	PELP1	97	96.994	Cebus_capucinus
ENSG00000141456	PELP1	100	100.000	ENSCATG00000031452	PELP1	100	98.455	Cercocebus_atys
ENSG00000141456	PELP1	100	92.929	ENSCLAG00000009775	PELP1	79	89.321	Chinchilla_lanigera
ENSG00000141456	PELP1	100	100.000	ENSCSAG00000013102	PELP1	96	97.373	Chlorocebus_sabaeus
ENSG00000141456	PELP1	58	69.767	ENSCPBG00000013021	PELP1	73	69.231	Chrysemys_picta_bellii
ENSG00000141456	PELP1	100	100.000	ENSCANG00000030679	PELP1	100	98.565	Colobus_angolensis_palliatus
ENSG00000141456	PELP1	100	92.929	ENSCGRG00001000840	Pelp1	79	86.726	Cricetulus_griseus_chok1gshd
ENSG00000141456	PELP1	100	95.960	ENSDNOG00000010696	PELP1	77	90.979	Dasypus_novemcinctus
ENSG00000141456	PELP1	100	78.788	ENSDORG00000013657	Pelp1	79	84.000	Dipodomys_ordii
ENSG00000141456	PELP1	100	88.889	ENSETEG00000017394	PELP1	72	83.790	Echinops_telfairi
ENSG00000141456	PELP1	100	97.980	ENSEASG00005017890	PELP1	79	91.324	Equus_asinus_asinus
ENSG00000141456	PELP1	100	97.980	ENSECAG00000020780	PELP1	79	91.435	Equus_caballus
ENSG00000141456	PELP1	100	94.949	ENSFCAG00000022191	PELP1	81	91.081	Felis_catus
ENSG00000141456	PELP1	100	92.929	ENSFDAG00000016451	PELP1	79	89.810	Fukomys_damarensis
ENSG00000141456	PELP1	100	100.000	ENSGGOG00000004778	PELP1	100	99.779	Gorilla_gorilla
ENSG00000141456	PELP1	95	87.857	ENSHGLG00000012390	PELP1	79	88.354	Heterocephalus_glaber_female
ENSG00000141456	PELP1	95	87.857	ENSHGLG00100013196	PELP1	79	87.570	Heterocephalus_glaber_male
ENSG00000141456	PELP1	100	97.980	ENSSTOG00000015512	PELP1	79	93.393	Ictidomys_tridecemlineatus
ENSG00000141456	PELP1	100	93.939	ENSJJAG00000013033	Pelp1	79	88.183	Jaculus_jaculus
ENSG00000141456	PELP1	90	65.169	ENSLACG00000007456	PELP1	67	40.184	Latimeria_chalumnae
ENSG00000141456	PELP1	100	92.929	ENSLAFG00000013717	PELP1	99	90.643	Loxodonta_africana
ENSG00000141456	PELP1	100	100.000	ENSMFAG00000042883	PELP1	100	98.565	Macaca_fascicularis
ENSG00000141456	PELP1	100	100.000	ENSMMUG00000010150	PELP1	100	98.565	Macaca_mulatta
ENSG00000141456	PELP1	100	100.000	ENSMNEG00000030617	PELP1	100	98.675	Macaca_nemestrina
ENSG00000141456	PELP1	100	100.000	ENSMLEG00000040717	PELP1	100	98.017	Mandrillus_leucophaeus
ENSG00000141456	PELP1	100	92.929	ENSMAUG00000012869	Pelp1	79	88.050	Mesocricetus_auratus
ENSG00000141456	PELP1	100	96.970	ENSMICG00000001633	PELP1	92	88.260	Microcebus_murinus
ENSG00000141456	PELP1	100	91.919	ENSMOCG00000010756	Pelp1	79	85.539	Microtus_ochrogaster
ENSG00000141456	PELP1	100	88.889	ENSMODG00000005708	PELP1	79	76.437	Monodelphis_domestica
ENSG00000141456	PELP1	100	92.929	MGP_CAROLIEiJ_G0016629	Pelp1	79	87.108	Mus_caroli
ENSG00000141456	PELP1	100	91.919	ENSMUSG00000018921	Pelp1	79	87.234	Mus_musculus
ENSG00000141456	PELP1	100	92.929	MGP_PahariEiJ_G0017760	Pelp1	79	87.332	Mus_pahari
ENSG00000141456	PELP1	100	92.929	MGP_SPRETEiJ_G0017465	Pelp1	79	86.435	Mus_spretus
ENSG00000141456	PELP1	100	96.970	ENSMPUG00000010785	PELP1	77	89.812	Mustela_putorius_furo
ENSG00000141456	PELP1	100	93.939	ENSMLUG00000002515	PELP1	76	90.022	Myotis_lucifugus
ENSG00000141456	PELP1	100	93.939	ENSNGAG00000011496	Pelp1	79	88.654	Nannospalax_galili
ENSG00000141456	PELP1	100	97.168	ENSNLEG00000017370	PELP1	100	97.020	Nomascus_leucogenys
ENSG00000141456	PELP1	100	88.889	ENSMEUG00000001946	PELP1	80	68.158	Notamacropus_eugenii
ENSG00000141456	PELP1	100	92.929	ENSODEG00000017225	PELP1	79	89.210	Octodon_degus
ENSG00000141456	PELP1	100	97.980	ENSOCUG00000014885	PELP1	66	91.243	Oryctolagus_cuniculus
ENSG00000141456	PELP1	100	53.535	ENSORLG00015012911	-	67	43.110	Oryzias_latipes_hsok
ENSG00000141456	PELP1	100	95.960	ENSOGAG00000003019	PELP1	79	94.589	Otolemur_garnettii
ENSG00000141456	PELP1	100	94.949	ENSOARG00000008090	PELP1	80	82.158	Ovis_aries
ENSG00000141456	PELP1	100	100.000	ENSPPAG00000038790	PELP1	100	99.322	Pan_paniscus
ENSG00000141456	PELP1	100	94.949	ENSPPRG00000024690	PELP1	97	87.703	Panthera_pardus
ENSG00000141456	PELP1	100	100.000	ENSPTRG00000008598	PELP1	100	99.492	Pan_troglodytes
ENSG00000141456	PELP1	100	100.000	ENSPANG00000024344	PELP1	100	98.455	Papio_anubis
ENSG00000141456	PELP1	100	57.576	ENSPKIG00000000176	PELP1	58	47.285	Paramormyrops_kingsleyae
ENSG00000141456	PELP1	100	74.747	ENSPSIG00000003171	PELP1	62	61.336	Pelodiscus_sinensis
ENSG00000141456	PELP1	100	92.929	ENSPEMG00000008891	Pelp1	79	85.339	Peromyscus_maniculatus_bairdii
ENSG00000141456	PELP1	100	87.879	ENSPCIG00000017329	PELP1	79	76.437	Phascolarctos_cinereus
ENSG00000141456	PELP1	95	87.857	ENSPCAG00000011476	PELP1	57	89.409	Procavia_capensis
ENSG00000141456	PELP1	100	97.980	ENSPCOG00000023542	PELP1	94	92.848	Propithecus_coquereli
ENSG00000141456	PELP1	100	95.960	ENSPVAG00000003992	PELP1	74	92.157	Pteropus_vampyrus
ENSG00000141456	PELP1	100	90.909	ENSRNOG00000019268	Pelp1	76	86.333	Rattus_norvegicus
ENSG00000141456	PELP1	100	100.000	ENSRBIG00000042665	PELP1	98	96.875	Rhinopithecus_bieti
ENSG00000141456	PELP1	100	100.000	ENSRROG00000030871	PELP1	95	98.578	Rhinopithecus_roxellana
ENSG00000141456	PELP1	100	100.000	ENSSBOG00000023118	PELP1	100	95.725	Saimiri_boliviensis_boliviensis
ENSG00000141456	PELP1	100	55.556	ENSSMAG00000008773	PELP1	57	42.324	Scophthalmus_maximus
ENSG00000141456	PELP1	100	95.960	ENSSARG00000008391	PELP1	65	90.182	Sorex_araneus
ENSG00000141456	PELP1	100	96.970	ENSSSCG00000017924	PELP1	79	88.952	Sus_scrofa
ENSG00000141456	PELP1	100	96.970	ENSTBEG00000010264	PELP1	82	92.717	Tupaia_belangeri
ENSG00000141456	PELP1	100	85.859	ENSTTRG00000007616	PELP1	74	88.515	Tursiops_truncatus
ENSG00000141456	PELP1	100	97.980	ENSUAMG00000009938	PELP1	74	93.378	Ursus_americanus
ENSG00000141456	PELP1	61	91.935	ENSUMAG00000014503	PELP1	65	77.677	Ursus_maritimus
ENSG00000141456	PELP1	100	97.980	ENSVVUG00000027526	PELP1	76	91.082	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003682	chromatin binding	17505058.	IDA	Function
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0005515	protein binding	16169070.20195357.20448663.21326211.30021884.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0006364	rRNA processing	-	TAS	Process
GO:0008134	transcription factor binding	17505058.	IPI	Function
GO:0035327	transcriptionally active chromatin	17505058.	IDA	Component
GO:0045944	positive regulation of transcription by RNA polymerase II	17505058.	IDA	Process
GO:0071339	MLL1 complex	15960975.	IDA	Component
GO:0071391	cellular response to estrogen stimulus	17505058.	IDA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotype

GWAS

PPI

Ortholog

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.