EuRBPDB

Ensembl ID

ENSG00000140105 (Gene tree)

Gene ID

7453

Gene Symbol

WARS

Alias

IFP53|IFI53

Full Name

tryptophanyl-tRNA synthetase

Gene Type

protein_coding

Specie

Homo_sapiens

Strand

Minus strand

Length

43,018 bases

Position

chr14:100,333,788-100,376,805

Accession

12729

Summary

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]