EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
27318497	Implications of NOVA1 suppression within the microenvironment of gastric cancer: association with immune cell dysregulation.	Gastric Cancer	2017 May	Kim EK	doi: 10.1007/s10120-016-0623-3
25299073	MiR-181b-5p downregulates NOVA1 to suppress proliferation, migration and invasion and promote apoptosis in astrocytoma.	PLoS One	2014 Oct 9	Zhi F	doi: 10.1371/journal.pone.0109124
18822086	Paraneoplastic antibody during follow-up of a patient with anti-Ri-associated paraneoplastic neurological syndrome.	Acta Neurol Scand	2009 May	Stich O	doi: 10.1111/j.1600-0404.2008.01102.x
26673617	NOVA1 inhibition by miR-146b-5p in the remnant tissue microenvironment defines occult residual disease after gastric cancer removal.	Oncotarget	2016 Jan 19	Yoon SO	doi: 10.18632/oncotarget.6542.
30082712	NOVA1 regulates hTERT splicing and cell growth in non-small cell lung cancer.	Nat Commun	2018 Aug 6	Ludlow AT	doi: 10.1038/s41467-018-05582-x.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr14	26448086	Missense_Mutation	novel	G466D	0.43
BLCA	chr14	26470430	Intron	rs766069193		0.41
BLCA	chr14	26448791	Missense_Mutation	novel	R231P	0.19
BLCA	chr14	26595548	Missense_Mutation	novel	G48S	0.15
BLCA	chr14	26447836	3'UTR	novel		0.33
BLCA	chr14	26595474	Silent	NA	I72I	0.17
BLCA	chr14	26448841	Silent	NA	I214I	0.33
BRCA	chr14	26470488	Intron	NA		0.24
BRCA	chr14	26470360	Intron	novel		0.1
BRCA	chr14	26479988	Missense_Mutation	NA	R146C	0.08
BRCA	chr14	26447938	3'UTR	novel		0.09
BRCA	chr14	26470262	Intron	novel		0.11
BRCA	chr14	26448590	Missense_Mutation	novel	A298E	0.13
BRCA	chr14	26595492	Silent	novel	G66G	0.07
CESC	chr14	26446381	3'UTR	novel		0.12
CESC	chr14	26446873	3'UTR	novel		0.15
CESC	chr14	26446176	3'UTR	novel		0.29
CESC	chr14	26447046	3'UTR	NA		0.4
CESC	chr14	26447891	3'UTR	novel		0.23
CESC	chr14	26447646	3'UTR	novel		0.43
CESC	chr14	26447837	3'UTR	novel		0.61
CESC	chr14	26597361	Missense_Mutation	novel	R26W	0.08
CESC	chr14	26597369	Missense_Mutation	NA	P23L	0.31
CESC	chr14	26447050	3'UTR	novel		0.4
CESC	chr14	26448930	Missense_Mutation	NA	L185V	0.29
CESC	chr14	26447875	3'UTR	novel		0.53
CESC	chr14	26549699	Intron	NA		0.25
CESC	chr14	26480033	Missense_Mutation	NA	E131Q	0.47
CESC	chr14	26448804	Frame_Shift_Del	novel	*E226Dfs2**	0.28
COAD	chr14	26480065	Frame_Shift_Ins	novel	*I120Nfs24**	0.32
COAD	chr14	26448099	Missense_Mutation	NA	E462K	0.39
COAD	chr14	26447837	3'UTR	novel		0.63
COAD	chr14	26448801	Nonsense_Mutation	novel	E228*	0.39
COAD	chr14	26480136	Silent	NA	T96T	0.41
COAD	chr14	26597336	Frame_Shift_Del	NA	*P34Lfs19**	0.3
COAD	chr14	26597336	Frame_Shift_Del	NA	P34*	0.24
COAD	chr14	26597361	Missense_Mutation	novel	R26W	0.36
COAD	chr14	26597336	Frame_Shift_Del	NA	*P34Lfs19**	0.34
COAD	chr14	26448677	Missense_Mutation	novel	G269V	0.27
COAD	chr14	26448046	Silent	novel	A479A	0.26
COAD	chr14	26597336	Frame_Shift_Del	NA	*P34Lfs19**	0.28
COAD	chr14	26448125	Missense_Mutation	novel	A453E	0.38
COAD	chr14	26448576	Missense_Mutation	novel	V303I	0.53
COAD	chr14	26597336	Frame_Shift_Del	NA	*P34Lfs19**	0.4
COAD	chr14	26480079	Missense_Mutation	rs185194463	F115L	0.49
COAD	chr14	26448523	Missense_Mutation	novel	N320K	0.16
COAD	chr14	26597336	Frame_Shift_Del	NA	*P34Lfs19**	0.33
COAD	chr14	26448936	Missense_Mutation	novel	A183S	0.06
COAD	chr14	26448314	Missense_Mutation	NA	A390V	0.22
COAD	chr14	26597336	Frame_Shift_Del	NA	*P34Lfs19**	0.25
COAD	chr14	26447836	3'UTR	novel		0.37
COAD	chr14	26597336	Frame_Shift_Del	NA	*P34Lfs19**	0.49
COAD	chr14	26470371	Intron	novel		0.15
COAD	chr14	26447837	3'UTR	novel		0.37
COAD	chr14	26597336	Frame_Shift_Del	NA	*P34Lfs19**	0.44
COAD	chr14	26595413	Missense_Mutation	novel	P93T	0.1
DLBC	chr14	26480072	Missense_Mutation	novel	E118K	0.05
ESCA	chr14	26446789	3'UTR	novel		0.21
ESCA	chr14	26446607	3'UTR	novel		0.2
ESCA	chr14	26447925	3'UTR	novel		0.28
ESCA	chr14	26447354	3'UTR	novel		0.18
ESCA	chr14	26448593	Missense_Mutation	novel	V297G	0.25
ESCA	chr14	26595487	Missense_Mutation	novel	G68V	0.26	KH_1
ESCA	chr14	26446417	3'UTR	novel		0.16
GBM	chr14	26448775	Silent	novel	L236L	0.07
GBM	chr14	26447891	3'UTR	novel		0.13
GBM	chr14	26448094	Silent	rs769569205	F463F	0.57
GBM	chr14	26472356	Silent	NA	S161S	0.15
GBM	chr14	26448748	Silent	novel	P245P	0.11
HNSC	chr14	26448297	Missense_Mutation	novel	N396D	0.22
HNSC	chr14	26480023	Missense_Mutation	novel	S134I	0.36
HNSC	chr14	26448550	Missense_Mutation	novel	D311E	0.28
HNSC	chr14	26470465	Intron	novel		0.11
HNSC	chr14	26448484	Silent	rs768040678	G333G	0.23
HNSC	chr14	26448840	Missense_Mutation	novel	N215Y	0.36
LGG	chr14	26470382	Intron	novel		0.21
LGG	chr14	26447971	Frame_Shift_Ins	novel	*Q504Hfs55**	0.28
LIHC	chr14	26595464	Nonsense_Mutation	novel	Q76*	0.29	KH_1
LIHC	chr14	26597490	5'UTR	novel		0.34
LIHC	chr14	26448050	Frame_Shift_Del	novel	*P478Qfs10**	0.13
LIHC	chr14	26447857	3'UTR	novel		0.36
LIHC	chr14	26480061	Silent	NA	R121R	0.33
LIHC	chr14	26448498	Missense_Mutation	NA	L329I	0.58
LIHC	chr14	26470336	Intron	novel		0.19
LIHC	chr14	26448498	Missense_Mutation	NA	L329I	0.12
LIHC	chr14	26480134	Missense_Mutation	novel	E97V	0.33
LIHC	chr14	26448130	Silent	NA	T451T	0.36
LIHC	chr14	26480039	Missense_Mutation	NA	K129E	0.16
LUAD	chr14	26479994	Missense_Mutation	NA	P144A	0.17
LUAD	chr14	26448264	Missense_Mutation	NA	A407S	0.33
LUAD	chr14	26447964	Missense_Mutation	NA	G507C	0.7
LUAD	chr14	26480143	Missense_Mutation	novel	G94V	0.12
LUAD	chr14	26448906	Missense_Mutation	NA	T193S	0.2
LUAD	chr14	26448610	Missense_Mutation	novel	H291Q	0.4
LUAD	chr14	26470349	Intron	novel		0.5
LUAD	chr14	26448705	Missense_Mutation	rs200148996	G260C	0.09
LUAD	chr14	26448780	Nonsense_Mutation	novel	E235*	0.26
LUAD	chr14	26448954	Missense_Mutation	NA	I177L	0.28
LUAD	chr14	26448933	Missense_Mutation	NA	G184C	0.06
LUAD	chr14	26448744	Missense_Mutation	NA	S247C	0.19
LUAD	chr14	26448362	Missense_Mutation	NA	S374T	0.22
LUAD	chr14	26448824	Missense_Mutation	NA	V220A	0.14
LUAD	chr14	26448678	Missense_Mutation	NA	G269R	0.19
LUAD	chr14	26480120	Missense_Mutation	NA	I102F	0.47
LUAD	chr14	26448294	Nonsense_Mutation	NA	G397*	0.2
LUAD	chr14	26448946	Frame_Shift_Del	novel	*N180Tfs6**	0.11
LUAD	chr14	26595410	Missense_Mutation	novel	G94C	0.18
LUAD	chr14	26448289	Silent	rs762691909	Y398Y	0.21
LUSC	chr14	26480143	Missense_Mutation	novel	G94V	0.18
LUSC	chr14	26480034	Silent	novel	T130T	0.4
LUSC	chr14	26448306	Missense_Mutation	NA	A393S	0.14
LUSC	chr14	26480062	Missense_Mutation	novel	R121Q	0.17
LUSC	chr14	26479974	Splice_Region	novel		0.23
LUSC	chr14	26448915	Missense_Mutation	novel	G190R	0.36
LUSC	chr14	26448079	Missense_Mutation	novel	R468S	0.25
LUSC	chr14	26470432	Intron	novel		0.21
LUSC	chr14	26448488	Nonsense_Mutation	NA	L332*	0.54
LUSC	chr14	26448115	Missense_Mutation	NA	Q456H	0.43
LUSC	chr14	26480109	Silent	NA	T105T	0.62
LUSC	chr14	26595463	Missense_Mutation	NA	Q76L	0.45	KH_1
LUSC	chr14	26448180	Missense_Mutation	novel	A435S	0.16
LUSC	chr14	26480125	Missense_Mutation	novel	C100F	0.31
LUSC	chr14	26448702	Missense_Mutation	novel	P261T	0.52
LUSC	chr14	26448636	Missense_Mutation	novel	A283S	0.52
LUSC	chr14	26448941	Missense_Mutation	novel	S181I	0.06
LUSC	chr14	26448942	Missense_Mutation	novel	S181R	0.06
LUSC	chr14	26448614	Missense_Mutation	NA	G290V	0.18
LUSC	chr14	26448922	Silent	novel	I187I	0.4
LUSC	chr14	26480036	Missense_Mutation	novel	T130S	0.17
LUSC	chr14	26448841	Silent	NA	I214I	0.18
OV	chr14	26448656	Missense_Mutation	NA	A276D	0.24
OV	chr14	26448458	Missense_Mutation	novel	T342I	0.22
OV	chr14	26595502	Missense_Mutation	novel	S63Y	0.08	KH_1
PAAD	chr14	26448086	Missense_Mutation	novel	G466D	0.08
PAAD	chr14	26472318	Splice_Site	novel	X173_splice	0.2
PRAD	chr14	26448300	Missense_Mutation	NA	T395S	0.25
PRAD	chr14	26448055	Silent	NA	G476G	0.36
PRAD	chr14	26448696	Missense_Mutation	NA	A263T	0.36
PRAD	chr14	26480000	Missense_Mutation	NA	V142I	0.31
READ	chr14	26479988	Missense_Mutation	NA	R146C	0.26
READ	chr14	26472378	Missense_Mutation	NA	S154Y	0.12
READ	chr14	26448074	Missense_Mutation	rs746531696	R470Q	0.33
READ	chr14	26595449	Missense_Mutation	NA	A81S	0.65	KH_1
READ	chr14	26597362	Silent	NA	S25S	0.53
READ	chr14	26448622	Frame_Shift_Ins	novel	*L288Cfs3**	0.06
READ	chr14	26472341	Missense_Mutation	novel	M166I	0.43
READ	chr14	26595414	Silent	novel	Y92Y	0.32
READ	chr14	26470479	Intron	novel		0.07
SARC	chr14	26447334	3'UTR	novel		0.52
SARC	chr14	26447412	3'UTR	novel		0.39
SARC	chr14	26479988	Missense_Mutation	NA	R146C	0.14
SARC	chr14	26447271	3'UTR	novel		0.19
SARC	chr14	26549737	Intron	novel		0.15
SKCM	chr14	26448271	Silent	rs200046551	P404P	0.91
SKCM	chr14	26448328	Frame_Shift_Ins	novel	*L385Ffs3**	0.62
SKCM	chr14	26470432	Intron	novel		0.39
SKCM	chr14	26480083	Missense_Mutation	novel	G114E	0.39
SKCM	chr14	26470465	Intron	novel		0.43
SKCM	chr14	26480063	Nonsense_Mutation	NA	R121*	0.19
SKCM	chr14	26448536	Missense_Mutation	novel	T316I	0.38
SKCM	chr14	26448785	Missense_Mutation	NA	A233V	0.28
SKCM	chr14	26447929	3'UTR	novel		0.09
SKCM	chr14	26480087	Missense_Mutation	novel	H113Y	0.28
SKCM	chr14	26448272	Missense_Mutation	NA	P404L	0.27
SKCM	chr14	26597393	Missense_Mutation	NA	G15E	0.24
SKCM	chr14	26448122	Missense_Mutation	rs766263962	R454K	0.64
SKCM	chr14	26479988	Missense_Mutation	NA	R146C	0.06
SKCM	chr14	26472388	Missense_Mutation	novel	L151M	0.25
SKCM	chr14	26448073	Silent	NA	R470R	0.33
SKCM	chr14	26448118	Missense_Mutation	novel	I455M	0.42
SKCM	chr14	26472376	Missense_Mutation	NA	P155S	0.85
SKCM	chr14	26448248	Missense_Mutation	NA	G412E	0.36
SKCM	chr14	26480121	Silent	novel	L101L	0.28
SKCM	chr14	26448506	Missense_Mutation	NA	G326E	0.09
SKCM	chr14	26472322	Nonsense_Mutation	NA	Q173*	0.84
SKCM	chr14	26448094	Silent	rs769569205	F463F	0.25
SKCM	chr14	26448160	Silent	NA	G441G	0.13
SKCM	chr14	26448677	Frame_Shift_Del	novel	*G269Dfs21**	0.34
SKCM	chr14	26448094	Silent	rs769569205	F463F	0.55
SKCM	chr14	26448219	Missense_Mutation	rs750803453	D422N	0.29
SKCM	chr14	26448220	Silent	NA	K421K	0.28
SKCM	chr14	26448321	Silent	NA	L388L	0.38
SKCM	chr14	26447964	Missense_Mutation	NA	G507S	0.27
SKCM	chr14	26448923	Missense_Mutation	NA	I187T	0.64
SKCM	chr14	26480063	Nonsense_Mutation	NA	R121*	0.23
SKCM	chr14	26448452	Missense_Mutation	novel	A344V	0.4
SKCM	chr14	26448896	Missense_Mutation	NA	A196V	0.36
SKCM	chr14	26448630	Missense_Mutation	novel	A285T	0.28
SKCM	chr14	26480063	Nonsense_Mutation	NA	R121*	0.24
SKCM	chr14	26448160	Silent	NA	G441G	0.57
SKCM	chr14	26448160	Silent	NA	G441G	0.21
SKCM	chr14	26480031	Missense_Mutation	NA	E131D	0.11
SKCM	chr14	26448889	Missense_Mutation	NA	M198I	0.07
SKCM	chr14	26448772	Silent	NA	I237I	0.41
SKCM	chr14	26448844	Silent	NA	G213G	0.12
SKCM	chr14	26448109	Silent	NA	S458S	0.18
SKCM	chr14	26448876	Missense_Mutation	novel	A203T	0.24
SKCM	chr14	26448455	Missense_Mutation	NA	G343E	0.25
SKCM	chr14	26448645	Missense_Mutation	NA	P280S	0.08
SKCM	chr14	26448916	Silent	NA	K189K	0.39
SKCM	chr14	26448587	Missense_Mutation	NA	A299V	0.51
SKCM	chr14	26448110	Missense_Mutation	novel	S458F	0.27
SKCM	chr14	26470432	Intron	novel		0.1
SKCM	chr14	26470367	Intron	novel		0.64
SKCM	chr14	26448672	Missense_Mutation	NA	P271S	0.39
SKCM	chr14	26448057	Missense_Mutation	NA	G476R	0.1
STAD	chr14	26448451	Silent	NA	A344A	0.34
STAD	chr14	26448776	Missense_Mutation	NA	L236R	0.22
STAD	chr14	26448776	Missense_Mutation	NA	L236R	0.2
STAD	chr14	26448479	Missense_Mutation	novel	G335V	0.08
STAD	chr14	26595432	Frame_Shift_Del	novel	*K87Pfs14**	0.12
STAD	chr14	26472363	Missense_Mutation	novel	K159T	0.2
STAD	chr14	26448128	Missense_Mutation	novel	G452V	0.53
STAD	chr14	26448544	Silent	novel	V313V	0.35
STAD	chr14	26470431	Intron	rs183029950		0.38
STAD	chr14	26479988	Missense_Mutation	NA	R146C	0.31
STAD	chr14	26448189	Silent	novel	L432L	0.18
STAD	chr14	26448953	Missense_Mutation	NA	I177T	0.05
STAD	chr14	26448776	Missense_Mutation	NA	L236R	0.17
STAD	chr14	26448292	Silent	rs770857304	G397G	0.19
STAD	chr14	26480078	Missense_Mutation	rs370779053	I116V	0.12
STAD	chr14	26447979	Missense_Mutation	NA	N502D	0.28
STAD	chr14	26480043	Silent	NA	V127V	0.05
STAD	chr14	26447983	Silent	NA	A500A	0.45
STAD	chr14	26470431	Intron	rs183029950		0.17
STAD	chr14	26448102	Frame_Shift_Ins	novel	*G461Rfs35**	0.19
STAD	chr14	26448759	Missense_Mutation	novel	Q242K	0.09
STAD	chr14	26448578	Missense_Mutation	NA	A302V	0.14
STAD	chr14	26448787	Silent	NA	K232K	0.07
STAD	chr14	26448919	Silent	NA	G188G	0.11
STAD	chr14	26448161	Missense_Mutation	NA	G441V	0.23
STAD	chr14	26595415	Missense_Mutation	NA	Y92C	0.17
STAD	chr14	26597448	5'UTR	novel		0.35
THYM	chr14	26446911	3'UTR	novel		0.13
THYM	chr14	26595478	Missense_Mutation	novel	T71K	0.07	KH_1
UCEC	chr14	26447776	3'UTR	novel		0.36
UCEC	chr14	26447422	3'UTR	novel		0.16
UCEC	chr14	26448875	Missense_Mutation	novel	A203V	0.38
UCEC	chr14	26597368	Silent	novel	P23P	0.41
UCEC	chr14	26448491	Missense_Mutation	novel	T331S	0.43
UCEC	chr14	26597336	Frame_Shift_Del	NA	*P34Lfs19**	0.19
UCEC	chr14	26447837	3'UTR	novel		0.4
UCEC	chr14	26470483	Intron	NA		0.34
UCEC	chr14	26446944	3'UTR	novel		0.18
UCEC	chr14	26446453	3'UTR	novel		0.15
UCEC	chr14	26448902	Missense_Mutation	NA	V194G	0.38
UCEC	chr14	26595422	Missense_Mutation	NA	D90N	0.38
UCEC	chr14	26447776	3'UTR	novel		1
UCEC	chr14	26470458	Intron	novel		0.53
UCEC	chr14	26480023	Missense_Mutation	novel	S134I	0.33
UCEC	chr14	26597500	5'UTR	novel		0.42
UCEC	chr14	26448266	Missense_Mutation	novel	A406V	0.39
UCEC	chr14	26446421	3'UTR	novel		0.32
UCEC	chr14	26447023	3'UTR	novel		0.19
UCEC	chr14	26447860	3'UTR	novel		0.33
UCEC	chr14	26447315	3'UTR	novel		0.51
UCEC	chr14	26470172	Intron	novel		0.47
UCEC	chr14	26595535	Missense_Mutation	novel	L52Q	0.21	KH_1
UCEC	chr14	26448766	Missense_Mutation	NA	Q239H	0.24
UCEC	chr14	26480010	Silent	NA	P138P	0.16
UCEC	chr14	26595530	Missense_Mutation	NA	V54I	0.42	KH_1
UCEC	chr14	26448107	Missense_Mutation	NA	K459T	0.19
UCEC	chr14	26595527	Missense_Mutation	NA	L55I	0.26	KH_1
UCEC	chr14	26597328	Missense_Mutation	novel	G37S	0.49
UCEC	chr14	26448829	Missense_Mutation	novel	E218D	0.1
UCEC	chr14	26470395	Intron	novel		0.16
UCEC	chr14	26446451	3'UTR	novel		0.18
UCEC	chr14	26597301	Missense_Mutation	novel	E46K	0.32
UCEC	chr14	26448910	Silent	NA	G191G	0.43
UCEC	chr14	26595422	Missense_Mutation	NA	D90Y	0.44
UCEC	chr14	26448286	Frame_Shift_Del	novel	*F399Lfs7**	0.15
UCEC	chr14	26597550	5'UTR	novel		0.47
UCEC	chr14	26446042	3'UTR	novel		0.61
UCEC	chr14	26447784	3'UTR	novel		0.16
UCEC	chr14	26479988	Missense_Mutation	NA	R146C	0.42
UCEC	chr14	26447640	3'UTR	novel		0.31
UCEC	chr14	26597336	Frame_Shift_Del	NA	*P34Lfs19**	0.18
UCEC	chr14	26446083	3'UTR	novel		0.28
UCEC	chr14	26446611	3'UTR	novel		0.24
UCEC	chr14	26480065	Missense_Mutation	novel	I120N	0.21
UCEC	chr14	26447098	3'UTR	novel		0.19
UCEC	chr14	26448594	Missense_Mutation	rs753209863	V297I	0.2
UCEC	chr14	26446991	3'UTR	novel		0.33
UCEC	chr14	26448262	Silent	novel	A407A	0.49
UCEC	chr14	26447190	3'UTR	novel		0.11
UCEC	chr14	26448243	Missense_Mutation	novel	E414K	0.51
UCEC	chr14	26446232	3'UTR	novel		0.27
UCEC	chr14	26447265	3'UTR	novel		0.12
UCEC	chr14	26447776	3'UTR	novel		0.7
UCEC	chr14	26448613	Silent	novel	G290G	0.33
UCEC	chr14	26470416	Intron	novel		0.15
UCEC	chr14	26446018	3'UTR	novel		0.39
UCEC	chr14	26446931	3'UTR	novel		0.53
UCEC	chr14	26470410	Intron	novel		0.46
UCEC	chr14	26447188	3'UTR	novel		0.39
UCEC	chr14	26447939	3'UTR	rs752765380		0.57
UCEC	chr14	26448452	Missense_Mutation	novel	A344D	0.46
UCEC	chr14	26470463	Intron	novel		0.38
UCEC	chr14	26472365	Silent	novel	T158T	0.45
UCEC	chr14	26597587	5'UTR	novel		0.44
UCEC	chr14	26446010	3'UTR	novel		0.52
UCEC	chr14	26446576	3'UTR	novel		0.12
UCEC	chr14	26448177	Frame_Shift_Ins	novel	*I436Sfs69**	0.06
UCEC	chr14	26595549	Silent	rs141059341	D47D	0.38
UCEC	chr14	26447582	3'UTR	novel		0.46
UCEC	chr14	26447869	3'UTR	novel		0.33
UCEC	chr14	26480018	Missense_Mutation	novel	L136I	0.48
UCEC	chr14	26446024	3'UTR	novel		0.29
UCEC	chr14	26597336	Frame_Shift_Del	NA	*P34Lfs19**	0.47
UCEC	chr14	26446698	3'UTR	novel		0.08
UCEC	chr14	26447092	3'UTR	NA		0.26
UCEC	chr14	26447435	3'UTR	novel		0.15
UCEC	chr14	26479988	Missense_Mutation	NA	R146C	0.38
UCEC	chr14	26447215	3'UTR	novel		0.29
UCEC	chr14	26447740	3'UTR	novel		0.18
UCEC	chr14	26446204	3'UTR	novel		0.17
UCEC	chr14	26446294	3'UTR	novel		0.47
UCEC	chr14	26597336	Frame_Shift_Del	NA	*P34Lfs19**	0.51
UCEC	chr14	26447405	3'UTR	novel		0.32
UCEC	chr14	26447634	3'UTR	novel		0.34
UCEC	chr14	26447745	3'UTR	novel		0.17
UCEC	chr14	26446901	3'UTR	novel		0.47
UCEC	chr14	26447634	3'UTR	novel		0.36
UCEC	chr14	26448096	Missense_Mutation	novel	F463V	0.43
UCEC	chr14	26448763	Missense_Mutation	novel	K240N	0.43
UCEC	chr14	26448908	Missense_Mutation	novel	A192V	0.19
UCEC	chr14	26470416	Intron	novel		0.45
UCEC	chr14	26470431	Intron	rs183029950		0.09
UCEC	chr14	26446096	3'UTR	novel		0.29
UCEC	chr14	26448252	Missense_Mutation	NA	L411I	0.5
UCEC	chr14	26447818	3'UTR	novel		0.47
UCEC	chr14	26448679	Silent	rs369917970	T268T	0.19
UCEC	chr14	26447915	3'UTR	novel		0.06
UCEC	chr14	26447698	3'UTR	novel		0.23
UCEC	chr14	26447106	3'UTR	novel		0.26
UCEC	chr14	26597336	Frame_Shift_Del	NA	*P34Lfs19**	0.45
UCEC	chr14	26448102	Frame_Shift_Ins	novel	*G461Rfs35**	0.16
UCEC	chr14	26470367	Intron	novel		0.42
UCEC	chr14	26480000	Missense_Mutation	NA	V142I	0.52
UCEC	chr14	26595516	Missense_Mutation	NA	S58R	0.4	KH_1
UCEC	chr14	26470357	Intron	novel		0.25
UCEC	chr14	26445965	3'UTR	novel		0.33
UCEC	chr14	26480132	Nonsense_Mutation	NA	R98*	0.42
UCEC	chr14	26447618	3'UTR	novel		0.36
UCEC	chr14	26448007	Silent	novel	I492I	0.53
UCEC	chr14	26448614	Missense_Mutation	novel	G290E	0.61
UCEC	chr14	26448515	Missense_Mutation	novel	A323D	0.16
UCEC	chr14	26447804	3'UTR	novel		0.18
UCEC	chr14	26549693	Intron	novel		0.25
UCEC	chr14	26448621	Missense_Mutation	NA	L288I	0.29
UCEC	chr14	26597335	Frame_Shift_Ins	rs765756993	E35*	0.47
UCEC	chr14	26597452	5'UTR	novel		0.37
UCEC	chr14	26447081	3'UTR	novel		0.48
UCEC	chr14	26447523	3'UTR	novel		0.45
UCEC	chr14	26447890	3'UTR	novel		0.39
UCEC	chr14	26470416	Intron	novel		0.28
UCEC	chr14	26480111	Missense_Mutation	novel	T105P	0.38
UCS	chr14	26480045	Missense_Mutation	novel	V127M	0.19

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1667	0.19769
CHOL	DEL	0.3611	0.00040262
HNSC	DEL	0.1169	0.0025503
KIRP	DEL	0.1701	0.085174
LUSC	DEL	0.2715	0.0082553
PAAD	DEL	0.0707	0.11332

Survival Analysis

Cancer	P-value	Q-value
STAD	0.0014	Kaplan-Meier Survival Analysis
SKCM	0.034	Kaplan-Meier Survival Analysis
PAAD	0.00011	Kaplan-Meier Survival Analysis
BLCA	0.0019	Kaplan-Meier Survival Analysis
CESC	0.004	Kaplan-Meier Survival Analysis
READ	0.045	Kaplan-Meier Survival Analysis
GBM	0.0079	Kaplan-Meier Survival Analysis
LIHC	0.014	Kaplan-Meier Survival Analysis
LGG	0.0073	Kaplan-Meier Survival Analysis
UVM	0.00013	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotype

GWAS

PPI

Paralog

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000139910 (Gene tree)
Gene ID: 4857
Gene Symbol: NOVA1
Alias: N
Full Name: NOVA alternative splicing regulator 1
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Minus strand
Length: 154,662 bases
Position: chr14:26,443,093-26,597,754
Accession: 7886
Summary: This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000447391	KH_1	PF00013.29	3e-45	1	3
ENSP00000447391	KH_1	PF00013.29	3e-45	2	3
ENSP00000447391	KH_1	PF00013.29	3e-45	3	3
ENSP00000438875	KH_1	PF00013.29	3.7e-45	1	3
ENSP00000438875	KH_1	PF00013.29	3.7e-45	2	3
ENSP00000438875	KH_1	PF00013.29	3.7e-45	3	3
ENSP00000408914	KH_1	PF00013.29	2e-30	1	2
ENSP00000408914	KH_1	PF00013.29	2e-30	2	2
ENSP00000449185	KH_1	PF00013.29	1e-23	1	2
ENSP00000449185	KH_1	PF00013.29	1e-23	2	2
ENSP00000299472	KH_1	PF00013.29	3e-16	1	1
ENSP00000459545	KH_1	PF00013.29	8.5e-13	1	1
ENSP00000342387	KH_1	PF00013.29	1.3e-12	1	1
ENSP00000448157	KH_1	PF00013.29	1.8e-12	1	1
ENSP00000449113	KH_1	PF00013.29	3.2e-09	1	1
ENSP00000408914	KH_2	PF07650.17	4.5e-09	1	1
ENSP00000299472	KH_2	PF07650.17	2.1e-05	1	1
ENSP00000449113	KH_2	PF07650.17	0.00015	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
17530930	Discovery and analysis of evolutionarily conserved intronic splicing regulatory elements.	PLoS Genet	2007 May 25	Yeo GW	-
29944885	Circ-UBR5: An exonic circular RNA and novel small nuclear RNA involved in RNA splicing.	Biochem Biophys Res Commun	2018 Sep 5	Qin M	doi: 10.1016/j.bbrc.2018.06.112
9154818	The neuronal RNA binding protein Nova-1 recognizes specific RNA targets in vitro and in vivo.	Mol Cell Biol	1997 Jun	Buckanovich RJ	-
28394091	Neuro-oncological ventral antigen 1 (NOVA1): Implications in neurological diseases and cancers.	Cell Prolif	2017 Aug	Xin Y	doi: 10.1111/cpr.12348
8558240	The onconeural antigen Nova-1 is a neuron-specific RNA-binding protein, the activity of which is inhibited by paraneoplastic antibodies.	J Neurosci	1996 Feb 1	Buckanovich RJ	-
9789075	The neuronal RNA-binding protein Nova-2 is implicated as the autoantigen targeted in POMA patients with dementia.	Proc Natl Acad Sci U S A	1998 Oct 27	Yang YY	-
10368286	Crystal structures of Nova-1 and Nova-2 K-homology RNA-binding domains.	Structure	1999 Feb 15	Lewis HA	-
8398153	Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system.	Neuron	1993 Oct	Buckanovich RJ	-
11948657	Role of HuD and other RNA-binding proteins in neural development and plasticity.	J Neurosci Res	2002 Apr 15	Perrone-Bizzozero N	-
11784037	pasilla, the Drosophila homologue of the human Nova-1 and Nova-2 proteins, is required for normal secretion in the salivary gland.	Dev Biol	2001 Nov 15	Seshaiah P	-
10735272	ANOVA, a putative astrocytic RNA-binding protein gene that maps to chromosome 19q13.3.	Neurogenetics	1997 May	Ueki K	-
10719891	Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability.	Neuron	2000 Feb	Jensen KB	-
18218628	Post-transcriptional regulation of neuro-oncological ventral antigen 1 by the neuronal RNA-binding proteins ELAV.	J Biol Chem	2008 Mar 21	Ratti A	doi: 10.1074/jbc.M706082200
17061352	Expression pattern of three putative RNA-binding proteins during early development of the sea urchin Paracentrotus lividus.	Gene Expr Patterns	2006 Oct	Rottinger E	-
27733149	RNA binding protein Nova1 promotes tumor growth in vivo and its potential mechanism as an oncogene may due to its interaction with GABAA Receptor-γ2.	J Biomed Sci	2016 Oct 12	Zhang YA	-
24608171	High expression of neuro-oncological ventral antigen 1 correlates with poor prognosis in hepatocellular carcinoma.	PLoS One	2014 Mar 7	Zhang YA	doi: 10.1371/journal.pone.0090955
27223325	NOVA2-mediated RNA regulation is required for axonal pathfinding during development.	Elife	2016 May 25	Saito Y	doi: 10.7554/eLife.14371.
26108672	Quantitative proteomic analysis shows differentially expressed HSPB1 in glioblastoma as a discriminating short from long survival factor and NOVA1 as a differentiation factor between low-grade astrocytoma and oligodendroglioma.	BMC Cancer	2015 Jun 25	Gimenez M	doi: 10.1186/s12885-015-1473-9.
29031089	17β-estradiol regulates the RNA-binding protein Nova1, which then regulates the alternative splicing of estrogen receptor β in the aging female rat brain.	Neurobiol Aging	2018 Jan	Shults CL	doi: 10.1016/j.neurobiolaging.2017.09.005
29118907	NOVA1 acts as an oncogene in osteosarcoma.	Am J Transl Res	2017 Oct 15	Li C	-
30696738	Genome-Wide Profiling of Cervical RNA-Binding Proteins Identifies Human Papillomavirus Regulation of RNASEH2A Expression by Viral E7 and E2F1.	MBio	2019 Jan 29	Xu J	doi: 10.1128/mBio.02687-18.
12808107	Nova regulates GABA(A) receptor gamma2 alternative splicing via a distal downstream UCAU-rich intronic splicing enhancer.	Mol Cell Biol	2003 Jul	Dredge BK	-
17655233	Scaffold-independent analysis of RNA-protein interactions: the Nova-1 KH3-RNA complex.	J Am Chem Soc	2007 Aug 22	Beuth B	-
21742260	Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1.	Structure	2011 Jul 13	Teplova M	doi: 10.1016/j.str.2011.05.002.
21622564	Regulatory roles of heterogeneous nuclear ribonucleoprotein M and Nova-1 protein in alternative splicing of dopamine D2 receptor pre-mRNA.	J Biol Chem	2011 Jul 15	Park E	doi: 10.1074/jbc.M110.206540
26367869	Embryonic Lethality Due to Arrested Cardiac Development in Psip1/Hdgfrp2 Double-Deficient Mice.	PLoS One	2015 Sep 14	Wang H	doi: 10.1371/journal.pone.0137797

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000549571	NOVA1-211	1005	XM_017021342	ENSP00000449185	173 (aa)	XP_016876831	F8VWX1
ENST00000483536	NOVA1-205	6575	-	ENSP00000448956	121 (aa)	-	F8VYI3
ENST00000547619	NOVA1-209	947	-	ENSP00000448157	211 (aa)	-	F8W659
ENST00000551754	NOVA1-212	488	-	-	- (aa)	-	-
ENST00000549146	NOVA1-210	592	XM_017021344	ENSP00000449113	96 (aa)	XP_016876833	F8VW64
ENST00000539517	NOVA1-206	3912	-	ENSP00000438875	507 (aa)	-	P51513
ENST00000347476	NOVA1-202	549	XM_011536800	ENSP00000299472	109 (aa)	XP_011535102	G8JLA5
ENST00000344429	NOVA1-201	896	-	ENSP00000342387	181 (aa)	-	P51513
ENST00000546546	NOVA1-207	563	-	ENSP00000448144	49 (aa)	-	H0YHZ1
ENST00000547415	NOVA1-208	500	-	-	- (aa)	-	-
ENST00000465357	NOVA1-204	3573	-	ENSP00000447391	483 (aa)	-	P51513
ENST00000449198	NOVA1-203	959	-	ENSP00000408914	277 (aa)	-	J3KQU3
ENST00000574031	NOVA1-213	1431	-	ENSP00000459545	152 (aa)	-	I3L2B5

Gene Model

Click here to download 's gene model file

Phenotype

ensgID	Trait	pValue	Pubmed ID
ENSG00000139910	Cholesterol, LDL	2.88838187385996E-8	17903299
ENSG00000139910	Erythrocyte Indices	1.33596097829214E-6	17903294
ENSG00000139910	Erythrocyte Indices	2.24395141055555E-9	17903294
ENSG00000139910	Blood Pressure	6.72493218764416E-7	17903302
ENSG00000139910	Bipolar Disorder	6.56E-5	19488044
ENSG00000139910	Blood Pressure	1.0050728E-005	-
ENSG00000139910	Platelet Function Tests	2.5950516E-008	-
ENSG00000139910	Platelet Function Tests	1.3679487E-008	-
ENSG00000139910	Education	7E-10	27225129
ENSG00000139910	Eosinophilic Esophagitis	7E-8	25407941
ENSG00000139910	Education	4E-8	27225129

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000139910	rs77092939	14	26579259	?	Educational attainment (college completion)	27225129	[NR]	1.0526897	EFO_0004784
ENSG00000139910	rs1245214	14	26466015	A	Cognitive performance	30038396	[0.012-0.025] unit decrease	0.0189	EFO_0008354
ENSG00000139910	rs178184	14	26509987	T	Educational attainment (MTAG)	30038396	[0.012-0.018] unit increase	0.0146	EFO_0004784
ENSG00000139910	rs1245213	14	26470268	A	Highest math class taken (MTAG)	30038396	[0.01-0.018] unit decrease	0.0139	EFO_0004875
ENSG00000139910	rs178203	14	26490116	T	Cognitive performance (MTAG)	30038396	[0.015-0.025] unit increase	0.0198	EFO_0008354
ENSG00000139910	rs1245193	14	26449262	?	General cognitive ability	29844566	z-score increase	4.853	EFO_0004337
ENSG00000139910	rs1885076	14	26574098	?	General cognitive ability	29844566	z-score increase	4.657	EFO_0004337
ENSG00000139910	rs178165	14	26558983	A	Intelligence	29942086	z-score decrease	5.934	EFO_0004337
ENSG00000139910	rs178183	14	26510206	T	Educational attainment (years of education)	30038396	[0.011-0.018] unit increase	0.0145	EFO_0004784
ENSG00000139910	rs8020034	14	26511894	?	Educational attainment (years of education)	30595370			EFO_0004784
ENSG00000139910	rs12101183	14	26466099	A	Educational attainment (years of education)	30038396	[0.011-0.017] unit increase	0.0143	EFO_0004784
ENSG00000139910	rs6575005	14	26484872	T	Sleep duration	30846698	unit increase	0.858	EFO_0005271

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000139910's network

Paralog

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000139910	NOVA1	64	41.667	ENSG00000088247	KHSRP	96	31.507
ENSG00000139910	NOVA1	91	37.931	ENSG00000183570	PCBP3	97	40.351
ENSG00000139910	NOVA1	71	35.135	ENSG00000197111	PCBP2	94	39.726
ENSG00000139910	NOVA1	72	36.709	ENSG00000090097	PCBP4	89	41.538
ENSG00000139910	NOVA1	65	33.803	ENSG00000073792	IGF2BP2	63	30.726
ENSG00000139910	NOVA1	56	39.062	ENSG00000165119	HNRNPK	64	43.103
ENSG00000139910	NOVA1	62	32.979	ENSG00000136231	IGF2BP3	86	30.570
ENSG00000139910	NOVA1	100	82.569	ENSG00000104967	NOVA2	100	77.500
ENSG00000139910	NOVA1	75	35.135	ENSG00000169564	PCBP1	70	40.541
ENSG00000139910	NOVA1	68	38.667	ENSG00000162613	FUBP1	52	31.609

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000139910	NOVA1	100	88.991	ENSAPOG00000002171	nova1	99	77.755	Acanthochromis_polyacanthus
ENSG00000139910	NOVA1	100	89.908	ENSAPOG00000006189	-	100	79.234	Acanthochromis_polyacanthus
ENSG00000139910	NOVA1	100	99.083	ENSAMEG00000015330	NOVA1	100	96.165	Ailuropoda_melanoleuca
ENSG00000139910	NOVA1	100	88.991	ENSACIG00000017818	nova1	98	73.333	Amphilophus_citrinellus
ENSG00000139910	NOVA1	100	89.908	ENSACIG00000007544	-	100	79.234	Amphilophus_citrinellus
ENSG00000139910	NOVA1	100	88.991	ENSAOCG00000011292	nova1	95	79.325	Amphiprion_ocellaris
ENSG00000139910	NOVA1	96	97.143	ENSAOCG00000013373	-	54	97.143	Amphiprion_ocellaris
ENSG00000139910	NOVA1	100	89.908	ENSAPEG00000016133	-	94	79.592	Amphiprion_percula
ENSG00000139910	NOVA1	100	88.991	ENSAPEG00000012502	nova1	99	79.325	Amphiprion_percula
ENSG00000139910	NOVA1	100	89.908	ENSATEG00000006500	NOVA1	100	79.032	Anabas_testudineus
ENSG00000139910	NOVA1	100	88.991	ENSATEG00000017565	nova1	98	73.516	Anabas_testudineus
ENSG00000139910	NOVA1	100	97.938	ENSAPLG00000008154	NOVA1	100	99.043	Anas_platyrhynchos
ENSG00000139910	NOVA1	100	98.958	ENSACAG00000000477	NOVA1	99	99.567	Anolis_carolinensis
ENSG00000139910	NOVA1	100	99.083	ENSANAG00000028004	NOVA1	99	99.784	Aotus_nancymaae
ENSG00000139910	NOVA1	100	88.991	ENSACLG00000003002	nova1	94	79.325	Astatotilapia_calliptera
ENSG00000139910	NOVA1	100	89.908	ENSACLG00000018329	-	100	75.723	Astatotilapia_calliptera
ENSG00000139910	NOVA1	100	88.991	ENSAMXG00000006702	nova1	100	80.368	Astyanax_mexicanus
ENSG00000139910	NOVA1	100	90.826	ENSAMXG00000033604	nova2	100	80.684	Astyanax_mexicanus
ENSG00000139910	NOVA1	100	99.803	ENSBTAG00000002170	NOVA1	100	99.803	Bos_taurus
ENSG00000139910	NOVA1	100	100.000	ENSCJAG00000039497	NOVA1	100	100.000	Callithrix_jacchus
ENSG00000139910	NOVA1	100	99.803	ENSCAFG00000029157	NOVA1	100	99.803	Canis_familiaris
ENSG00000139910	NOVA1	100	98.104	ENSCAFG00020024149	-	100	98.104	Canis_lupus_dingo
ENSG00000139910	NOVA1	100	99.803	ENSCHIG00000018944	NOVA1	100	99.803	Capra_hircus
ENSG00000139910	NOVA1	100	99.083	ENSTSYG00000014033	NOVA1	99	99.758	Carlito_syrichta
ENSG00000139910	NOVA1	99	91.739	ENSCAPG00000010512	NOVA1	100	93.795	Cavia_aperea
ENSG00000139910	NOVA1	100	99.606	ENSCPOG00000030872	NOVA1	100	99.606	Cavia_porcellus
ENSG00000139910	NOVA1	100	100.000	ENSCCAG00000026410	NOVA1	100	100.000	Cebus_capucinus
ENSG00000139910	NOVA1	100	100.000	ENSCATG00000039944	NOVA1	100	100.000	Cercocebus_atys
ENSG00000139910	NOVA1	100	98.958	ENSCLAG00000008948	NOVA1	99	99.784	Chinchilla_lanigera
ENSG00000139910	NOVA1	100	99.803	ENSCSAG00000015814	NOVA1	100	99.803	Chlorocebus_sabaeus
ENSG00000139910	NOVA1	100	97.830	ENSCHOG00000006617	NOVA1	100	97.830	Choloepus_hoffmanni
ENSG00000139910	NOVA1	100	99.803	ENSCPBG00000027677	NOVA1	100	99.803	Chrysemys_picta_bellii
ENSG00000139910	NOVA1	100	99.448	ENSCANG00000023898	NOVA1	100	99.448	Colobus_angolensis_palliatus
ENSG00000139910	NOVA1	100	99.803	ENSCGRG00001024030	Nova1	100	99.803	Cricetulus_griseus_chok1gshd
ENSG00000139910	NOVA1	100	98.958	ENSCGRG00000004816	Nova1	98	99.784	Cricetulus_griseus_crigri
ENSG00000139910	NOVA1	100	89.908	ENSCSEG00000005887	NOVA1	100	79.234	Cynoglossus_semilaevis
ENSG00000139910	NOVA1	100	88.991	ENSCSEG00000017718	nova1	99	75.600	Cynoglossus_semilaevis
ENSG00000139910	NOVA1	100	88.991	ENSCVAG00000011460	nova1	94	78.054	Cyprinodon_variegatus
ENSG00000139910	NOVA1	100	90.826	ENSCVAG00000014373	-	100	74.249	Cyprinodon_variegatus
ENSG00000139910	NOVA1	81	88.636	ENSCVAG00000014025	NOVA1	96	79.179	Cyprinodon_variegatus
ENSG00000139910	NOVA1	100	91.743	ENSDARG00000020178	nova1	99	92.857	Danio_rerio
ENSG00000139910	NOVA1	100	90.826	ENSDARG00000017673	nova2	100	80.242	Danio_rerio
ENSG00000139910	NOVA1	100	98.958	ENSDNOG00000034618	NOVA1	100	99.758	Dasypus_novemcinctus
ENSG00000139910	NOVA1	100	99.803	ENSDORG00000012633	Nova1	100	99.803	Dipodomys_ordii
ENSG00000139910	NOVA1	100	84.375	ENSETEG00000002159	NOVA1	100	88.069	Echinops_telfairi
ENSG00000139910	NOVA1	100	72.477	ENSEBUG00000016201	NOVA1	97	65.440	Eptatretus_burgeri
ENSG00000139910	NOVA1	100	83.486	ENSEBUG00000008930	NOVA1	98	71.491	Eptatretus_burgeri
ENSG00000139910	NOVA1	100	98.958	ENSEASG00005018649	NOVA1	100	99.740	Equus_asinus_asinus
ENSG00000139910	NOVA1	100	99.803	ENSECAG00000037301	NOVA1	100	99.803	Equus_caballus
ENSG00000139910	NOVA1	98	97.849	ENSEEUG00000013658	NOVA1	100	88.363	Erinaceus_europaeus
ENSG00000139910	NOVA1	100	88.991	ENSELUG00000012346	-	100	76.482	Esox_lucius
ENSG00000139910	NOVA1	100	89.908	ENSELUG00000017375	nova1	100	78.400	Esox_lucius
ENSG00000139910	NOVA1	100	99.803	ENSFCAG00000004226	NOVA1	100	99.803	Felis_catus
ENSG00000139910	NOVA1	100	99.803	ENSFALG00000005703	NOVA1	100	99.803	Ficedula_albicollis
ENSG00000139910	NOVA1	100	98.958	ENSFDAG00000007704	NOVA1	100	98.619	Fukomys_damarensis
ENSG00000139910	NOVA1	100	90.826	ENSFHEG00000020456	-	100	79.637	Fundulus_heteroclitus
ENSG00000139910	NOVA1	100	88.991	ENSFHEG00000004626	nova1	100	77.597	Fundulus_heteroclitus
ENSG00000139910	NOVA1	100	89.908	ENSGMOG00000019162	-	75	88.546	Gadus_morhua
ENSG00000139910	NOVA1	100	88.991	ENSGMOG00000011253	nova1	100	77.419	Gadus_morhua
ENSG00000139910	NOVA1	100	99.803	ENSGALG00000009850	NOVA1	100	99.803	Gallus_gallus
ENSG00000139910	NOVA1	100	76.923	ENSGAFG00000003656	-	100	76.726	Gambusia_affinis
ENSG00000139910	NOVA1	100	88.991	ENSGAFG00000016382	nova1	99	78.279	Gambusia_affinis
ENSG00000139910	NOVA1	100	88.991	ENSGACG00000020175	nova1	95	82.664	Gasterosteus_aculeatus
ENSG00000139910	NOVA1	100	89.908	ENSGACG00000012628	-	98	76.890	Gasterosteus_aculeatus
ENSG00000139910	NOVA1	89	99.701	ENSGAGG00000007839	NOVA1	94	99.701	Gopherus_agassizii
ENSG00000139910	NOVA1	100	83.471	ENSGAGG00000018398	-	84	94.059	Gopherus_agassizii
ENSG00000139910	NOVA1	100	100.000	ENSGGOG00000016495	NOVA1	100	100.000	Gorilla_gorilla
ENSG00000139910	NOVA1	100	88.991	ENSHBUG00000018561	nova1	99	79.536	Haplochromis_burtoni
ENSG00000139910	NOVA1	100	89.908	ENSHBUG00000002485	NOVA1	100	76.673	Haplochromis_burtoni
ENSG00000139910	NOVA1	100	99.803	ENSHGLG00000003180	NOVA1	100	99.803	Heterocephalus_glaber_female
ENSG00000139910	NOVA1	100	97.959	ENSHGLG00100000445	-	100	80.992	Heterocephalus_glaber_male
ENSG00000139910	NOVA1	100	98.958	ENSHGLG00100000791	NOVA1	90	99.758	Heterocephalus_glaber_male
ENSG00000139910	NOVA1	100	89.908	ENSHCOG00000008366	nova1	97	79.536	Hippocampus_comes
ENSG00000139910	NOVA1	100	89.908	ENSHCOG00000019136	-	100	78.831	Hippocampus_comes
ENSG00000139910	NOVA1	100	91.743	ENSIPUG00000019551	nova2	100	76.571	Ictalurus_punctatus
ENSG00000139910	NOVA1	100	88.991	ENSIPUG00000018651	nova1	100	78.895	Ictalurus_punctatus
ENSG00000139910	NOVA1	100	98.958	ENSSTOG00000020788	NOVA1	99	99.784	Ictidomys_tridecemlineatus
ENSG00000139910	NOVA1	100	99.803	ENSJJAG00000012915	Nova1	100	99.803	Jaculus_jaculus
ENSG00000139910	NOVA1	76	97.222	ENSKMAG00000015047	-	97	92.045	Kryptolebias_marmoratus
ENSG00000139910	NOVA1	100	88.991	ENSKMAG00000014225	nova1	95	80.421	Kryptolebias_marmoratus
ENSG00000139910	NOVA1	93	82.759	ENSKMAG00000006068	-	77	89.720	Kryptolebias_marmoratus
ENSG00000139910	NOVA1	100	88.991	ENSLBEG00000028542	nova1	95	80.126	Labrus_bergylta
ENSG00000139910	NOVA1	100	89.908	ENSLBEG00000003511	NOVA1	100	77.980	Labrus_bergylta
ENSG00000139910	NOVA1	100	98.958	ENSLACG00000005669	NOVA1	99	98.804	Latimeria_chalumnae
ENSG00000139910	NOVA1	100	88.991	ENSLACG00000015223	nova2	99	81.670	Latimeria_chalumnae
ENSG00000139910	NOVA1	100	99.083	ENSLOCG00000009727	NOVA1	100	93.097	Lepisosteus_oculatus
ENSG00000139910	NOVA1	100	88.991	ENSLOCG00000014804	nova2	99	80.040	Lepisosteus_oculatus
ENSG00000139910	NOVA1	100	99.803	ENSLAFG00000006455	NOVA1	100	99.803	Loxodonta_africana
ENSG00000139910	NOVA1	100	100.000	ENSMFAG00000035425	NOVA1	100	100.000	Macaca_fascicularis
ENSG00000139910	NOVA1	100	99.803	ENSMMUG00000004271	NOVA1	100	99.803	Macaca_mulatta
ENSG00000139910	NOVA1	100	100.000	ENSMNEG00000040302	NOVA1	100	100.000	Macaca_nemestrina
ENSG00000139910	NOVA1	100	99.083	ENSMLEG00000034714	NOVA1	100	99.783	Mandrillus_leucophaeus
ENSG00000139910	NOVA1	100	89.908	ENSMAMG00000016281	NOVA1	100	79.234	Mastacembelus_armatus
ENSG00000139910	NOVA1	100	88.991	ENSMAMG00000021272	nova1	94	79.536	Mastacembelus_armatus
ENSG00000139910	NOVA1	100	89.908	ENSMZEG00005024407	-	100	76.673	Maylandia_zebra
ENSG00000139910	NOVA1	100	88.991	ENSMZEG00005023362	nova1	94	79.325	Maylandia_zebra
ENSG00000139910	NOVA1	100	98.958	ENSMGAG00000012359	NOVA1	100	99.281	Meleagris_gallopavo
ENSG00000139910	NOVA1	100	96.694	ENSMAUG00000000995	-	100	96.694	Mesocricetus_auratus
ENSG00000139910	NOVA1	100	99.803	ENSMICG00000034677	NOVA1	100	100.000	Microcebus_murinus
ENSG00000139910	NOVA1	100	99.803	ENSMOCG00000006277	Nova1	100	99.803	Microtus_ochrogaster
ENSG00000139910	NOVA1	100	90.826	ENSMMOG00000005092	-	94	79.874	Mola_mola
ENSG00000139910	NOVA1	99	79.137	ENSMMOG00000006066	nova1	95	75.952	Mola_mola
ENSG00000139910	NOVA1	100	98.958	ENSMODG00000001830	NOVA1	95	99.784	Monodelphis_domestica
ENSG00000139910	NOVA1	99	81.013	ENSMALG00000010422	-	86	79.630	Monopterus_albus
ENSG00000139910	NOVA1	100	88.991	ENSMALG00000005081	nova1	89	79.149	Monopterus_albus
ENSG00000139910	NOVA1	73	91.045	ENSMALG00000010432	-	67	91.045	Monopterus_albus
ENSG00000139910	NOVA1	100	99.606	MGP_CAROLIEiJ_G0017728	Nova1	100	99.606	Mus_caroli
ENSG00000139910	NOVA1	100	99.606	ENSMUSG00000021047	Nova1	100	99.606	Mus_musculus
ENSG00000139910	NOVA1	100	99.606	MGP_PahariEiJ_G0029485	Nova1	100	99.606	Mus_pahari
ENSG00000139910	NOVA1	100	99.606	MGP_SPRETEiJ_G0018570	Nova1	100	99.606	Mus_spretus
ENSG00000139910	NOVA1	100	99.803	ENSMPUG00000005462	NOVA1	100	99.803	Mustela_putorius_furo
ENSG00000139910	NOVA1	100	98.958	ENSMLUG00000016716	NOVA1	100	99.041	Myotis_lucifugus
ENSG00000139910	NOVA1	99	99.265	ENSNGAG00000023231	Nova1	100	99.132	Nannospalax_galili
ENSG00000139910	NOVA1	98	80.769	ENSNBRG00000016812	-	97	69.681	Neolamprologus_brichardi
ENSG00000139910	NOVA1	90	100.000	ENSNBRG00000016780	-	79	89.474	Neolamprologus_brichardi
ENSG00000139910	NOVA1	100	88.991	ENSNBRG00000008100	nova1	98	76.566	Neolamprologus_brichardi
ENSG00000139910	NOVA1	100	100.000	ENSNLEG00000033958	NOVA1	100	100.000	Nomascus_leucogenys
ENSG00000139910	NOVA1	99	97.321	ENSMEUG00000009112	NOVA1	98	86.735	Notamacropus_eugenii
ENSG00000139910	NOVA1	86	100.000	ENSOPRG00000007199	-	72	100.000	Ochotona_princeps
ENSG00000139910	NOVA1	100	98.958	ENSODEG00000001059	NOVA1	100	99.783	Octodon_degus
ENSG00000139910	NOVA1	100	89.908	ENSONIG00000007665	NOVA1	100	79.074	Oreochromis_niloticus
ENSG00000139910	NOVA1	98	80.000	ENSONIG00000015810	nova1	100	74.225	Oreochromis_niloticus
ENSG00000139910	NOVA1	100	98.958	ENSOANG00000014015	NOVA1	100	99.183	Ornithorhynchus_anatinus
ENSG00000139910	NOVA1	100	99.803	ENSOCUG00000017622	NOVA1	100	99.803	Oryctolagus_cuniculus
ENSG00000139910	NOVA1	100	88.991	ENSORLG00000000350	nova1	94	79.114	Oryzias_latipes
ENSG00000139910	NOVA1	100	90.826	ENSORLG00000027761	-	100	76.731	Oryzias_latipes
ENSG00000139910	NOVA1	100	88.991	ENSORLG00020004573	nova1	99	78.557	Oryzias_latipes_hni
ENSG00000139910	NOVA1	100	90.826	ENSORLG00020019124	-	100	77.115	Oryzias_latipes_hni
ENSG00000139910	NOVA1	100	90.826	ENSORLG00015007890	-	100	77.559	Oryzias_latipes_hsok
ENSG00000139910	NOVA1	100	88.991	ENSORLG00015000650	nova1	98	79.325	Oryzias_latipes_hsok
ENSG00000139910	NOVA1	100	90.826	ENSOMEG00000022949	-	100	79.435	Oryzias_melastigma
ENSG00000139910	NOVA1	100	88.991	ENSOMEG00000015479	nova1	99	77.755	Oryzias_melastigma
ENSG00000139910	NOVA1	100	98.958	ENSOGAG00000025938	NOVA1	100	99.802	Otolemur_garnettii
ENSG00000139910	NOVA1	100	98.958	ENSOARG00000004870	NOVA1	98	99.784	Ovis_aries
ENSG00000139910	NOVA1	100	99.422	ENSPPAG00000038980	NOVA1	99	99.784	Pan_paniscus
ENSG00000139910	NOVA1	100	99.803	ENSPPRG00000015429	NOVA1	100	99.803	Panthera_pardus
ENSG00000139910	NOVA1	100	99.083	ENSPTIG00000009518	NOVA1	91	99.783	Panthera_tigris_altaica
ENSG00000139910	NOVA1	100	100.000	ENSPTRG00000006229	NOVA1	100	100.000	Pan_troglodytes
ENSG00000139910	NOVA1	100	100.000	ENSPANG00000004891	NOVA1	100	100.000	Papio_anubis
ENSG00000139910	NOVA1	100	99.083	ENSPKIG00000001428	NOVA1	100	96.901	Paramormyrops_kingsleyae
ENSG00000139910	NOVA1	100	89.908	ENSPKIG00000005431	nova2	99	80.040	Paramormyrops_kingsleyae
ENSG00000139910	NOVA1	100	98.958	ENSPSIG00000007132	NOVA1	99	99.784	Pelodiscus_sinensis
ENSG00000139910	NOVA1	100	88.991	ENSPMGG00000005975	nova1	99	76.305	Periophthalmus_magnuspinnatus
ENSG00000139910	NOVA1	100	89.908	ENSPMGG00000009801	-	100	78.400	Periophthalmus_magnuspinnatus
ENSG00000139910	NOVA1	100	99.803	ENSPEMG00000006503	Nova1	100	99.803	Peromyscus_maniculatus_bairdii
ENSG00000139910	NOVA1	100	98.958	ENSPCIG00000024683	NOVA1	100	99.740	Phascolarctos_cinereus
ENSG00000139910	NOVA1	100	90.826	ENSPFOG00000016392	-	100	77.264	Poecilia_formosa
ENSG00000139910	NOVA1	100	88.991	ENSPFOG00000018009	nova1	99	79.775	Poecilia_formosa
ENSG00000139910	NOVA1	99	80.892	ENSPLAG00000003504	-	100	77.115	Poecilia_latipinna
ENSG00000139910	NOVA1	100	88.991	ENSPLAG00000015391	nova1	93	84.892	Poecilia_latipinna
ENSG00000139910	NOVA1	100	88.991	ENSPMEG00000016376	nova1	98	79.036	Poecilia_mexicana
ENSG00000139910	NOVA1	100	90.826	ENSPMEG00000019140	-	100	77.115	Poecilia_mexicana
ENSG00000139910	NOVA1	100	88.991	ENSPREG00000011614	nova1	98	76.506	Poecilia_reticulata
ENSG00000139910	NOVA1	99	80.255	ENSPREG00000018946	-	100	76.923	Poecilia_reticulata
ENSG00000139910	NOVA1	100	99.803	ENSPPYG00000005714	NOVA1	100	99.803	Pongo_abelii
ENSG00000139910	NOVA1	99	95.694	ENSPCAG00000010303	NOVA1	100	85.602	Procavia_capensis
ENSG00000139910	NOVA1	100	99.174	ENSPCOG00000016857	NOVA1	100	100.000	Propithecus_coquereli
ENSG00000139910	NOVA1	100	98.619	ENSPVAG00000002564	NOVA1	100	98.619	Pteropus_vampyrus
ENSG00000139910	NOVA1	100	88.991	ENSPNYG00000015521	nova1	90	79.325	Pundamilia_nyererei
ENSG00000139910	NOVA1	100	89.908	ENSPNYG00000022283	-	100	75.723	Pundamilia_nyererei
ENSG00000139910	NOVA1	100	91.743	ENSPNAG00000009171	nova2	100	81.087	Pygocentrus_nattereri
ENSG00000139910	NOVA1	100	88.991	ENSPNAG00000024351	nova1	99	80.659	Pygocentrus_nattereri
ENSG00000139910	NOVA1	100	99.278	ENSRNOG00000031440	Nova1	100	99.585	Rattus_norvegicus
ENSG00000139910	NOVA1	100	99.422	ENSRBIG00000026331	NOVA1	100	98.801	Rhinopithecus_bieti
ENSG00000139910	NOVA1	100	99.083	ENSRROG00000040203	NOVA1	100	99.783	Rhinopithecus_roxellana
ENSG00000139910	NOVA1	100	99.083	ENSSBOG00000034029	NOVA1	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000139910	NOVA1	100	98.958	ENSSHAG00000004907	NOVA1	100	99.281	Sarcophilus_harrisii
ENSG00000139910	NOVA1	98	96.644	ENSSFOG00015010887	NOVA1	77	95.000	Scleropages_formosus
ENSG00000139910	NOVA1	100	89.908	ENSSFOG00015004204	nova2	100	77.959	Scleropages_formosus
ENSG00000139910	NOVA1	93	89.474	ENSSFOG00015010909	-	76	96.970	Scleropages_formosus
ENSG00000139910	NOVA1	100	89.908	ENSSMAG00000020189	-	100	78.831	Scophthalmus_maximus
ENSG00000139910	NOVA1	100	88.991	ENSSMAG00000006485	nova1	68	81.144	Scophthalmus_maximus
ENSG00000139910	NOVA1	100	88.991	ENSSDUG00000020704	nova1	98	80.042	Seriola_dumerili
ENSG00000139910	NOVA1	100	89.908	ENSSDUG00000001795	-	100	78.088	Seriola_dumerili
ENSG00000139910	NOVA1	100	88.991	ENSSLDG00000006713	nova1	97	79.536	Seriola_lalandi_dorsalis
ENSG00000139910	NOVA1	100	89.908	ENSSLDG00000003193	-	100	79.234	Seriola_lalandi_dorsalis
ENSG00000139910	NOVA1	100	98.958	ENSSARG00000002599	NOVA1	100	99.783	Sorex_araneus
ENSG00000139910	NOVA1	78	96.809	ENSSPUG00000006528	-	99	93.814	Sphenodon_punctatus
ENSG00000139910	NOVA1	100	98.958	ENSSPUG00000006539	NOVA1	100	99.740	Sphenodon_punctatus
ENSG00000139910	NOVA1	100	88.991	ENSSPAG00000001033	nova1	94	79.325	Stegastes_partitus
ENSG00000139910	NOVA1	100	89.908	ENSSPAG00000008284	NOVA1	100	75.723	Stegastes_partitus
ENSG00000139910	NOVA1	100	99.803	ENSSSCG00000024396	NOVA1	100	99.803	Sus_scrofa
ENSG00000139910	NOVA1	100	99.803	ENSTGUG00000011799	NOVA1	100	99.803	Taeniopygia_guttata
ENSG00000139910	NOVA1	100	89.908	ENSTRUG00000016275	-	100	75.723	Takifugu_rubripes
ENSG00000139910	NOVA1	100	89.908	ENSTNIG00000011634	nova1	100	81.992	Tetraodon_nigroviridis
ENSG00000139910	NOVA1	76	91.566	ENSTNIG00000018993	NOVA1	98	78.886	Tetraodon_nigroviridis
ENSG00000139910	NOVA1	100	96.450	ENSTBEG00000009774	NOVA1	100	96.450	Tupaia_belangeri
ENSG00000139910	NOVA1	91	89.154	ENSTTRG00000006010	NOVA1	100	89.154	Tursiops_truncatus
ENSG00000139910	NOVA1	100	99.803	ENSUAMG00000025822	NOVA1	100	99.803	Ursus_americanus
ENSG00000139910	NOVA1	100	98.958	ENSUMAG00000023125	NOVA1	100	99.740	Ursus_maritimus
ENSG00000139910	NOVA1	100	99.803	ENSVPAG00000007807	NOVA1	100	99.803	Vicugna_pacos
ENSG00000139910	NOVA1	100	99.083	ENSVVUG00000029367	NOVA1	100	99.740	Vulpes_vulpes
ENSG00000139910	NOVA1	100	96.654	ENSXETG00000010244	nova1	100	96.654	Xenopus_tropicalis
ENSG00000139910	NOVA1	100	90.826	ENSXCOG00000009738	NOVA1	100	77.976	Xiphophorus_couchianus
ENSG00000139910	NOVA1	100	90.826	ENSXMAG00000013130	-	100	79.435	Xiphophorus_maculatus
ENSG00000139910	NOVA1	100	88.991	ENSXMAG00000017880	nova1	98	76.506	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000398	mRNA splicing, via spliceosome	-	IEA	Process
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0003729	mRNA binding	-	IEA	Function
GO:0005515	protein binding	27733149.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0006396	RNA processing	8398153.	TAS	Process
GO:0007268	chemical synaptic transmission	8558240.	TAS	Process
GO:0007626	locomotory behavior	8558240.	TAS	Process
GO:0008380	RNA splicing	8398153.	TAS	Process
GO:0043231	intracellular membrane-bounded organelle	-	IDA	Component
GO:0051252	regulation of RNA metabolic process	-	IEA	Process
GO:0120163	negative regulation of cold-induced thermogenesis	27635635.	ISS	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotype

GWAS

PPI

Paralog

Ortholog

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.