EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr9	104132023	Missense_Mutation	NA	M1002I	0.51
BLCA	chr9	104132063	Missense_Mutation	NA	L1016F	0.09
BLCA	chr9	104113400	Missense_Mutation	novel	D447H	0.11
BLCA	chr9	104138156	Silent	NA	T1136T	0.37
BLCA	chr9	104118210	Missense_Mutation	NA	E611K	0.88
BLCA	chr9	104095317	5'UTR	novel		0.3
BLCA	chr9	104129809	Missense_Mutation	NA	M985I	0.24
BLCA	chr9	104127430	Missense_Mutation	NA	D914N	0.17
BLCA	chr9	104095439	Missense_Mutation	NA	E19K	0.43
BLCA	chr9	104139256	Missense_Mutation	novel	I1179V	0.24
BLCA	chr9	104125014	Missense_Mutation	novel	R787K	0.14
BLCA	chr9	104135932	Intron	novel		0.48
BLCA	chr9	104111797	Missense_Mutation	rs770558864	Q413E	0.22
BLCA	chr9	104118351	Missense_Mutation	novel	D658H	0.05
BLCA	chr9	104129811	Missense_Mutation	novel	R986T	0.29
BLCA	chr9	104120128	Missense_Mutation	NA	E700K	0.47
BLCA	chr9	104111752	Missense_Mutation	rs781477090	L398V	0.16
BLCA	chr9	104102018	Missense_Mutation	rs760941119	R232H	0.15
BRCA	chr9	104129753	Missense_Mutation	novel	Q967E	0.1
BRCA	chr9	104124962	Missense_Mutation	rs776131090	E770K	0.41
BRCA	chr9	104118293	Silent	NA	K638K	0.44
BRCA	chr9	104102165	Missense_Mutation	novel	I281R	0.05
BRCA	chr9	104127403	Missense_Mutation	NA	D905N	0.12
BRCA	chr9	104114021	Missense_Mutation	novel	R491T	0.23
BRCA	chr9	104124923	Missense_Mutation	NA	E757Q	0.14
BRCA	chr9	104124925	Missense_Mutation	novel	E757D	0.1
BRCA	chr9	104100188	Silent	NA	L192L	0.56
BRCA	chr9	104118176	Silent	novel	G599G	0.11
BRCA	chr9	104134566	Missense_Mutation	NA	G1087D	0.12
CESC	chr9	104124965	Nonsense_Mutation	NA	E771*	0.22
CESC	chr9	104120094	Silent	rs777662020	L688L	0.23
CESC	chr9	104113428	Missense_Mutation	NA	R456K	0.24
CESC	chr9	104120029	Missense_Mutation	novel	A667P	0.11
CESC	chr9	104102545	Missense_Mutation	rs751500565	R331H	0.11
CESC	chr9	104102137	Frame_Shift_Del	NA	I274*	0.41
CESC	chr9	104126710	Missense_Mutation	novel	E841K	0.35
COAD	chr9	104139346	3'UTR	rs780808034		0.35
COAD	chr9	104129700	Missense_Mutation	NA	G949V	0.38
COAD	chr9	104139411	3'UTR	novel		0.09
COAD	chr9	104102452	Missense_Mutation	NA	E300G	0.27
COAD	chr9	104102498	Silent	rs371568094	S315S	0.27
COAD	chr9	104114703	Missense_Mutation	NA	K515N	0.08
COAD	chr9	104123220	Frame_Shift_Del	NA	*T751Pfs9**	0.3
COAD	chr9	104111663	Missense_Mutation	novel	K368T	0.05
COAD	chr9	104118228	Nonsense_Mutation	novel	Q617*	0.27
COAD	chr9	104114038	Nonsense_Mutation	novel	E497*	0.49
COAD	chr9	104129809	Missense_Mutation	NA	M985I	0.33
COAD	chr9	104132114	Missense_Mutation	novel	A1033T	0.06
COAD	chr9	104123220	Frame_Shift_Del	NA	*T751Pfs9**	0.3
COAD	chr9	104102018	Missense_Mutation	rs760941119	R232H	0.39
COAD	chr9	104114078	Missense_Mutation	novel	Y510C	0.41
COAD	chr9	104100169	Frame_Shift_Del	NA	*K188Rfs5**	0.1
COAD	chr9	104102137	Frame_Shift_Del	NA	I274*	0.39
COAD	chr9	104118286	Missense_Mutation	rs754224682	A636V	0.37
COAD	chr9	104123220	Frame_Shift_Del	NA	*T751Pfs9**	0.41
COAD	chr9	104132024	Missense_Mutation	novel	K1003E	0.04
COAD	chr9	104102544	Missense_Mutation	rs180923911	R331C	0.4
COAD	chr9	104139209	Missense_Mutation	novel	D1163G	0.27
COAD	chr9	104102102	Missense_Mutation	NA	V260D	0.44
COAD	chr9	104100100	Missense_Mutation	NA	S163C	0.18
COAD	chr9	104100141	Frame_Shift_Del	NA	I179*	0.13
COAD	chr9	104120099	Missense_Mutation	novel	I690N	0.31
COAD	chr9	104102115	Missense_Mutation	novel	Q264H	0.56
COAD	chr9	104111599	Missense_Mutation	NA	A347T	0.19
COAD	chr9	104118239	Missense_Mutation	NA	M620I	0.16
COAD	chr9	104095456	Silent	rs147385187	D24D	0.06
COAD	chr9	104120155	Splice_Site	novel	X709_splice	0.14
DLBC	chr9	104113409	Missense_Mutation	novel	A450S	0.37
DLBC	chr9	104102499	Missense_Mutation	rs199917130	A316T	0.11
ESCA	chr9	104095529	Silent	novel	L49L	0.14
ESCA	chr9	104102427	Missense_Mutation	novel	T292P	0.44
ESCA	chr9	104123138	Missense_Mutation	novel	M721I	0.23
ESCA	chr9	104139152	Missense_Mutation	novel	S1144L	0.39
ESCA	chr9	104098520	Silent	novel	F131F	0.65
ESCA	chr9	104125039	Frame_Shift_Ins	novel	*L798Tfs12**	0.25
ESCA	chr9	104120138	Missense_Mutation	novel	A703G	0.48
GBM	chr9	104123120	Silent	NA	L715L	0.48
GBM	chr9	104118204	Silent	novel	L609L	0.11
GBM	chr9	104099652	Silent	novel	I150I	0.31
HNSC	chr9	104102077	Missense_Mutation	novel	E252Q	0.13
HNSC	chr9	104134464	Missense_Mutation	rs369017202	N1053S	0.09
HNSC	chr9	104129698	Silent	novel	F948F	0.8
HNSC	chr9	104138105	Missense_Mutation	novel	L1119F	0.38
HNSC	chr9	104114009	Missense_Mutation	NA	R487H	0.18
HNSC	chr9	104126673	Missense_Mutation	novel	E828D	0.48
HNSC	chr9	104102013	Missense_Mutation	novel	L230F	0.12
HNSC	chr9	104114001	Silent	novel	Q484Q	0.06
KIRC	chr9	104114744	Missense_Mutation	NA	L529P	0.07
KIRP	chr9	104139493	3'UTR	novel		0.27
KIRP	chr9	104127463	Frame_Shift_Del	novel	*E925Kfs11**	0.14
KIRP	chr9	104111732	Missense_Mutation	novel	E391G	0.3
KIRP	chr9	104120034	Silent	novel	R668R	0.21
KIRP	chr9	104100426	Missense_Mutation	NA	L210S	0.31
LAML	chr9	104134451	In_Frame_Ins	novel	G1051_A1052insVPG	0.05
LAML	chr9	104113343	Nonsense_Mutation	novel	Q428*	0.09
LAML	chr9	104126755	Missense_Mutation	novel	V856L	0.06
LGG	chr9	104114731	Missense_Mutation	novel	L525F	0.09
LGG	chr9	104118262	Missense_Mutation	novel	F628C	0.09
LGG	chr9	104125100	Nonsense_Mutation	novel	Q816*	0.35
LGG	chr9	104098504	Missense_Mutation	NA	R126T	0.06
LIHC	chr9	104123220	Frame_Shift_Del	NA	*T751Pfs9**	0.4
LIHC	chr9	104132127	Splice_Site	NA	X1036_splice	0.44
LIHC	chr9	104102468	Missense_Mutation	novel	E305D	0.27
LIHC	chr9	104100141	Frame_Shift_Del	NA	I179*	0.15
LUAD	chr9	104127437	Missense_Mutation	NA	N916I	0.86
LUAD	chr9	104127411	Missense_Mutation	novel	Q907H	0.67
LUAD	chr9	104127459	Missense_Mutation	novel	E923D	0.11
LUAD	chr9	104114809	Missense_Mutation	novel	N551D	0.06
LUAD	chr9	104114821	Missense_Mutation	novel	D555N	0.19
LUAD	chr9	104127426	In_Frame_Ins	novel	E912_L913insNMW	0.06
LUAD	chr9	104127351	Silent	novel	T887T	0.29
LUAD	chr9	104114006	Missense_Mutation	novel	S486C	0.06
LUAD	chr9	104114036	Missense_Mutation	rs751981726	Y496C	0.7
LUAD	chr9	104102457	Missense_Mutation	rs764814020	A302S	0.62
LUAD	chr9	104102149	Missense_Mutation	novel	A276P	0.34
LUAD	chr9	104102188	Missense_Mutation	NA	D289H	0.26
LUAD	chr9	104139226	Missense_Mutation	NA	A1169S	0.38
LUAD	chr9	104127426	Nonsense_Mutation	novel	*L913Nfs4**	0.06
LUAD	chr9	104127428	Nonsense_Mutation	novel	L913*	0.03
LUAD	chr9	104127327	Missense_Mutation	NA	K879N	0.39
LUSC	chr9	104095465	Silent	novel	F27F	0.24
LUSC	chr9	104125039	Frame_Shift_Ins	novel	*L798Tfs12**	0.09
LUSC	chr9	104123150	Missense_Mutation	novel	E725D	0.4
LUSC	chr9	104127391	Missense_Mutation	novel	E901K	0.21
LUSC	chr9	104114765	Missense_Mutation	NA	S536F	0.08
LUSC	chr9	104126722	Missense_Mutation	NA	E845Q	0.15
LUSC	chr9	104102185	In_Frame_Ins	novel	K288delinsITQ	0.16
LUSC	chr9	104127307	Missense_Mutation	NA	E873K	0.22
LUSC	chr9	104100168	Frame_Shift_Ins	novel	*E189Gfs3**	0.2
OV	chr9	104096153	Silent	NA	R58R	0.54
OV	chr9	104113974	Missense_Mutation	novel	E475D	0.37
OV	chr9	104118319	Missense_Mutation	novel	T647N	0.03
OV	chr9	104134521	Missense_Mutation	NA	V1072D	0.26
OV	chr9	104125039	Silent	NA	Q795Q	0.16
PAAD	chr9	104116239	Missense_Mutation	rs772638726	R571C	0.19
PAAD	chr9	104113406	Nonsense_Mutation	novel	E449*	0.16
PAAD	chr9	104134467	Missense_Mutation	novel	A1054V	0.03
PAAD	chr9	104127424	Missense_Mutation	novel	E912K	0.03
PRAD	chr9	104096193	Missense_Mutation	novel	A72P	0.22
PRAD	chr9	104120078	Missense_Mutation	novel	D683G	0.06
PRAD	chr9	104127430	Missense_Mutation	NA	D914N	0.39
PRAD	chr9	104139184	Missense_Mutation	rs778988810	V1155I	0.48
READ	chr9	104123220	Frame_Shift_Del	NA	*T751Pfs9**	0.41
READ	chr9	104101999	Nonsense_Mutation	NA	E226*	0.09
READ	chr9	104120106	Missense_Mutation	novel	E692D	0.36
READ	chr9	104123205	Nonsense_Mutation	novel	E744*	0.37
READ	chr9	104138139	Silent	novel	L1131L	0.46
SARC	chr9	104126706	Silent	rs755697502	Q839Q	0.31
SKCM	chr9	104139264	Silent	rs144844202	K1181K	0.36
SKCM	chr9	104139293	Missense_Mutation	novel	K1191R	0.23
SKCM	chr9	104135882	Intron	novel		0.28
SKCM	chr9	104126759	Missense_Mutation	novel	M857K	0.78
SKCM	chr9	104111581	Missense_Mutation	novel	D341N	0.37
SKCM	chr9	104129768	Silent	NA	L972L	0.13
SKCM	chr9	104120111	Missense_Mutation	novel	E694G	0.89
SKCM	chr9	104120032	Nonsense_Mutation	novel	R668*	0.36
SKCM	chr9	104114059	Missense_Mutation	NA	P504S	0.31
SKCM	chr9	104101967	Missense_Mutation	rs747631183	S215L	0.27
STAD	chr9	104100140	Frame_Shift_Ins	novel	*I179Nfs13**	0.22
STAD	chr9	104127323	Frame_Shift_Del	novel	*E880Rfs2**	0.16
STAD	chr9	104123220	Frame_Shift_Del	NA	*T751Pfs9**	0.14
STAD	chr9	104127461	Missense_Mutation	novel	A924D	0.19
STAD	chr9	104127407	Missense_Mutation	NA	S906F	0.11
STAD	chr9	104123220	Frame_Shift_Del	NA	*T751Pfs9**	0.32
STAD	chr9	104100169	Frame_Shift_Del	NA	*K188Rfs5**	0.29
STAD	chr9	104102557	Frame_Shift_Del	NA	*N337Ifs9**	0.21
STAD	chr9	104114009	Missense_Mutation	NA	R487H	0.22
STAD	chr9	104139346	3'UTR	rs780808034		0.4
STAD	chr9	104138042	Missense_Mutation	NA	I1098M	0.09
STAD	chr9	104100141	Frame_Shift_Del	NA	I179*	0.46
STAD	chr9	104123220	Frame_Shift_Del	NA	*T751Pfs9**	0.42
STAD	chr9	104129733	Nonsense_Mutation	novel	*N960delinsKYFI**	0.14
STAD	chr9	104123220	Frame_Shift_Del	NA	*T751Pfs9**	0.16
STAD	chr9	104113992	Missense_Mutation	novel	K481N	0.1
STAD	chr9	104100141	Frame_Shift_Del	NA	I179*	0.16
STAD	chr9	104123220	Frame_Shift_Del	NA	*T751Pfs9**	0.19
STAD	chr9	104116224	Frame_Shift_Ins	novel	*E568Gfs13**	0.3
STAD	chr9	104111754	Silent	rs184176278	L398L	0.26
STAD	chr9	104123148	Missense_Mutation	novel	E725K	0.34
STAD	chr9	104123220	Frame_Shift_Del	NA	*T751Pfs9**	0.25
STAD	chr9	104120159	Frame_Shift_Del	novel	*K711Sfs5**	0.09
STAD	chr9	104102188	Missense_Mutation	NA	D289H	0.31
STAD	chr9	104123220	Frame_Shift_Del	NA	*T751Pfs9**	0.42
STAD	chr9	104113338	Missense_Mutation	NA	A426V	0.23
THCA	chr9	104129733	Nonsense_Mutation	novel	*N960delinsKYFI**	0.04
THCA	chr9	104102185	In_Frame_Ins	novel	K288delinsITQ	0.17
UCEC	chr9	104102137	Frame_Shift_Del	NA	I274*	0.46
UCEC	chr9	104116242	Nonsense_Mutation	NA	R572*	0.37
UCEC	chr9	104134530	Missense_Mutation	novel	G1075E	0.05
UCEC	chr9	104126709	Silent	novel	L840L	0.24
UCEC	chr9	104129843	Nonsense_Mutation	novel	R997*	0.48
UCEC	chr9	104095375	5'UTR	novel		0.11
UCEC	chr9	104139187	Missense_Mutation	NA	L1156I	0.41
UCEC	chr9	104102064	Silent	novel	V247V	0.15
UCEC	chr9	104095451	Missense_Mutation	novel	F23L	0.51
UCEC	chr9	104111713	Missense_Mutation	rs760655816	A385T	0.47
UCEC	chr9	104114720	Missense_Mutation	novel	C521Y	0.53
UCEC	chr9	104095317	5'UTR	novel		0.21
UCEC	chr9	104101967	Missense_Mutation	rs747631183	S215L	0.43
UCEC	chr9	104138057	Silent	novel	L1103L	0.26
UCEC	chr9	104125034	Missense_Mutation	NA	A794T	0.17
UCEC	chr9	104102137	Frame_Shift_Del	NA	I274*	0.5
UCEC	chr9	104102149	Missense_Mutation	novel	A276S	0.28
UCEC	chr9	104116239	Missense_Mutation	rs772638726	R571C	0.44
UCEC	chr9	104095306	5'UTR	novel		0.08
UCEC	chr9	104096169	Missense_Mutation	novel	D64N	0.38
UCEC	chr9	104113459	Silent	novel	K466K	0.33
UCEC	chr9	104114741	Missense_Mutation	novel	S528Y	0.43
UCEC	chr9	104111607	Silent	novel	E349E	0.23
UCEC	chr9	104138142	Missense_Mutation	rs201237445	R1132C	0.35
UCEC	chr9	104114068	Nonsense_Mutation	novel	R507*	0.13
UCEC	chr9	104139444	3'UTR	novel		0.13
UCEC	chr9	104120068	Nonsense_Mutation	novel	E680*	0.41
UCEC	chr9	104099663	Missense_Mutation	novel	L154S	0.32
UCEC	chr9	104100095	Missense_Mutation	novel	I161M	0.55
UCEC	chr9	104116246	Missense_Mutation	NA	Y573C	0.18
UCEC	chr9	104102143	Missense_Mutation	novel	I274L	0.44
UCEC	chr9	104127373	Nonsense_Mutation	novel	E895*	0.41
UCEC	chr9	104095366	5'UTR	novel		0.41
UCEC	chr9	104125043	Missense_Mutation	novel	K797E	0.24
UCEC	chr9	104132007	Splice_Site	novel	X998_splice	0.29
UCEC	chr9	104102499	Missense_Mutation	rs199917130	A316T	0.29
UCEC	chr9	104102013	Silent	novel	L230L	0.13
UCEC	chr9	104116240	Missense_Mutation	rs367564983	R571H	0.49
UCEC	chr9	104113994	Missense_Mutation	rs776518199	R482H	0.26
UCEC	chr9	104118272	Silent	novel	D631D	0.46
UCEC	chr9	104138098	Missense_Mutation	novel	A1117V	0.27
UCEC	chr9	104118287	Frame_Shift_Ins	novel	*V639Sfs4**	0.39
UCEC	chr9	104096169	Missense_Mutation	novel	D64Y	0.17
UCEC	chr9	104123220	Frame_Shift_Del	NA	*T751Pfs9**	0.26
UCEC	chr9	104111651	Missense_Mutation	novel	E364G	0.33
UCEC	chr9	104098488	Missense_Mutation	novel	N121D	0.22
UCEC	chr9	104099684	Splice_Site	NA	X160_splice	0.44
UCEC	chr9	104116225	Frame_Shift_Del	novel	*E568Nfs2**	0.08
UCEC	chr9	104113468	Missense_Mutation	novel	N469K	0.32
UCEC	chr9	104123220	Frame_Shift_Del	NA	*T751Pfs9**	0.4
UCEC	chr9	104129786	Missense_Mutation	NA	K978E	0.15
UCEC	chr9	104139244	Missense_Mutation	NA	Q1175K	0.27
UCEC	chr9	104134437	Frame_Shift_Del	novel	*S1046Lfs37**	0.42
UCEC	chr9	104139141	Missense_Mutation	NA	F1140L	0.26
UCEC	chr9	104100108	Nonsense_Mutation	novel	E166*	0.21
UCEC	chr9	104118363	Missense_Mutation	novel	T662A	0.25
UCEC	chr9	104138142	Missense_Mutation	rs201237445	R1132C	0.22
UCEC	chr9	104100169	Frame_Shift_Del	NA	*K188Rfs5**	0.28
UCEC	chr9	104126730	Silent	novel	I847I	0.56
UCEC	chr9	104140527	3'UTR	novel		0.42
UCEC	chr9	104102473	Missense_Mutation	novel	Q307R	0.35
UCEC	chr9	104100202	Missense_Mutation	rs200540431	T197M	0.33
UCEC	chr9	104102136	Frame_Shift_Ins	novel	*I274Nfs5**	0.32
UCEC	chr9	104123220	Frame_Shift_Del	NA	*T751Pfs9**	0.37
UCEC	chr9	104098520	Silent	novel	F131F	0.43
UCEC	chr9	104096210	Silent	novel	A77A	0.4
UCEC	chr9	104113979	Missense_Mutation	novel	S477N	0.3
UCS	chr9	104111779	Missense_Mutation	novel	N407D	0.96
UVM	chr9	104116299	Missense_Mutation	novel	L591M	0.13
UVM	chr9	104139367	3'UTR	novel		0.35

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	DEL	0.3676	0.11788
CHOL	DEL	0.4722	0.067545
LAML	DEL	0.0105	0.24147
LIHC	DEL	0.2622	0.12467
PRAD	AMP	0.0732	0.059049
THCA	DEL	0.0401	0.24038
THYM	DEL	0.0163	0.022012
UCS	DEL	0.6071	0.089783

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0024	Kaplan-Meier Survival Analysis
KIRC	0.0001	Kaplan-Meier Survival Analysis
STAD	0.018	Kaplan-Meier Survival Analysis
SARC	0.0019	Kaplan-Meier Survival Analysis
MESO	0.03	Kaplan-Meier Survival Analysis
ACC	0.00025	Kaplan-Meier Survival Analysis
SKCM	0.013	Kaplan-Meier Survival Analysis
KIRP	0.005	Kaplan-Meier Survival Analysis
PAAD	0.036	Kaplan-Meier Survival Analysis
PCPG	0.024	Kaplan-Meier Survival Analysis
CESC	0.012	Kaplan-Meier Survival Analysis
READ	0.024	Kaplan-Meier Survival Analysis
KICH	0.039	Kaplan-Meier Survival Analysis
LIHC	0.0033	Kaplan-Meier Survival Analysis
LGG	0.00053	Kaplan-Meier Survival Analysis
LUAD	0.00058	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Phenotype

GWAS

PPI

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000136824 (Gene tree)
Gene ID: 10592
Gene Symbol: SMC2
Alias: hCAP-E|CAP-E|SMC2L1
Full Name: structural maintenance of chromosomes 2
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Plus strand
Length: 47,572 bases
Position: chr9:104,093,848-104,141,419
Accession: 14011
Summary: (Structural Maintenance Of Chromosomes 2) is a Protein Coding gene. Among its related pathways are Chromatin Regulation / Acetylation and DNA Damage. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity. An important paralog of this gene is SMC1A.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000493955	SMC2-205	1408	-	ENSP00000431534	166 (aa)	-	A0A0C4DGE5
ENST00000374787	SMC2-202	4266	XM_011518148	ENSP00000363919	1197 (aa)	XP_011516450	O95347
ENST00000374793	SMC2-203	5909	XM_006716933	ENSP00000363925	1197 (aa)	XP_006716996	O95347
ENST00000440179	SMC2-204	705	-	ENSP00000414999	145 (aa)	-	Q5T821
ENST00000286398	SMC2-201	5992	XM_017014211	ENSP00000286398	1197 (aa)	XP_016869700	O95347

Gene Model

Click here to download ENSG00000136824's gene model file

Phenotype

ensgID	Trait	pValue	Pubmed ID
ENSG00000136824	Body Mass Index	4.48423550859295E-5	17903300
ENSG00000136824	Body Mass Index	8.25066069844119E-5	17903300
ENSG00000136824	Body Mass Index	5.1217632948083E-5	17903300
ENSG00000136824	Platelet Function Tests	2.4949900E-005	-
ENSG00000136824	Cytarabine	5E-7	24483146

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000136824	rs2417487	9	104125300	A	Pancreatic cancer	29422604	[1.05-1.12]	1.09	EFO_0002618
ENSG00000136824	rs4742903	9	104094512	T	High-grade serous ovarian cancer	28346442	[1.04130585570624-1.10789968145028]	1.0740868	EFO_1001516
ENSG00000136824	rs7859034	9	104103411	G	Pancreatic ductal adenocarcinoma	30541042	[1.08-1.16]	1.1111112	EFO_0002618
ENSG00000136824	rs4742903	9	104094512	C	Breast cancer	29059683	[0.02-0.045] unit increase	0.0325	EFO_0000305

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000136824's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000136824	SMC2	99	41.379	FBgn0027783	SMC2	99	40.971	Drosophila_melanogaster
ENSG00000136824	SMC2	100	93.103	ENSMUSG00000028312	Smc2	100	93.206	Mus_musculus
ENSG00000136824	SMC2	100	40.690	YFR031C		99	36.984	Saccharomyces_cerevisiae

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000228	nuclear chromosome	10958694.	IDA	Component
GO:0000793	condensed chromosome	12589063.	IDA	Component
GO:0000796	condensin complex	10958694.11136719.	IDA	Component
GO:0003697	single-stranded DNA binding	-	IEA	Function
GO:0005515	protein binding	12589063.17113138.17268547.21633354.23728299.26496610.30021884.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	12589063.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0005737	cytoplasm	10958694.12589063.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0007076	mitotic chromosome condensation	11136719.	IDA	Process
GO:0010032	meiotic chromosome condensation	-	IEA	Process
GO:0045132	meiotic chromosome segregation	-	IEA	Process
GO:0046982	protein heterodimerization activity	9789013.	IPI	Function
GO:0051301	cell division	-	IEA	Process
GO:0051383	kinetochore organization	-	IEA	Process
GO:0070062	extracellular exosome	19056867.	HDA	Component

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Phenotype

GWAS

PPI

Ortholog

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.