EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr19	47373683	Missense_Mutation	novel	L683F	0.32
BLCA	chr19	47373641	Missense_Mutation	rs141177029	R669C	0.39
BLCA	chr19	47381315	Missense_Mutation	NA	G1097R	0.2
BLCA	chr19	47379816	Missense_Mutation	novel	R938L	0.59
BLCA	chr19	47362646	Missense_Mutation	rs760692334	P516A	0.22
BLCA	chr19	47375999	Missense_Mutation	rs775749081	E795K	0.16
BLCA	chr19	47355302	Silent	novel	F323F	0.34
BLCA	chr19	47353374	Missense_Mutation	rs760482688	T115M	0.14
BLCA	chr19	47379795	Missense_Mutation	novel	A931G	0.21
BLCA	chr19	47353433	Missense_Mutation	NA	R135G	0.08
BLCA	chr19	47355189	Missense_Mutation	novel	L286I	0.25
BLCA	chr19	47381278	Silent	rs138943688	I1084I	0.08
BLCA	chr19	47362593	Missense_Mutation	NA	G498A	0.29
BLCA	chr19	47376047	Nonsense_Mutation	NA	Q811*	0.25
BRCA	chr19	47375942	Missense_Mutation	novel	R776W	0.18
BRCA	chr19	47380855	Nonsense_Mutation	NA	Q1008*	0.16
BRCA	chr19	47353348	Silent	NA	I106I	0.23
CESC	chr19	47379908	Missense_Mutation	NA	E969K	0.32
CESC	chr19	47377170	Silent	rs767879978	P890P	0.27
CESC	chr19	47379815	Nonsense_Mutation	rs146308675	R938*	0.11
CESC	chr19	47367050	Missense_Mutation	novel	E555Q	0.22
CESC	chr19	47352999	5'UTR	novel		0.3
CESC	chr19	47377116	Missense_Mutation	NA	M872I	0.14
CESC	chr19	47357863	Splice_Region	novel		0.57
COAD	chr19	47355055	Missense_Mutation	novel	R241H	0.12
COAD	chr19	47352946	5'UTR	novel		0.21
COAD	chr19	47382025	Missense_Mutation	rs762513967	L1115P	0.37
COAD	chr19	47380984	Missense_Mutation	NA	C1051R	0.33
COAD	chr19	47353635	Missense_Mutation	novel	A202V	0.15
COAD	chr19	47380892	Frame_Shift_Del	NA	*H1022Ifs135**	0.24
COAD	chr19	47352944	5'UTR	novel		0.15
COAD	chr19	47377186	Missense_Mutation	rs756746132	V896I	0.5
COAD	chr19	47375674	Frame_Shift_Del	NA	*P760Qfs12**	0.35
COAD	chr19	47377136	Missense_Mutation	NA	L879P	0.26
COAD	chr19	47376491	Missense_Mutation	rs376387877	V844I	0.5
COAD	chr19	47353482	Missense_Mutation	NA	R151P	0.08
COAD	chr19	47373646	Silent	NA	R670R	0.33
COAD	chr19	47380990	Missense_Mutation	NA	T1053A	0.21
COAD	chr19	47379825	Missense_Mutation	rs139543869	A941V	0.21
COAD	chr19	47380957	Missense_Mutation	rs148368794	A1042T	0.11
COAD	chr19	47355198	Missense_Mutation	rs199846132	D289N	0.15
COAD	chr19	47355241	Missense_Mutation	NA	P303H	0.26
COAD	chr19	47380935	Silent	NA	P1034P	0.28
COAD	chr19	47377099	Splice_Site	NA	X867_splice	0.3
COAD	chr19	47375991	Missense_Mutation	NA	L792P	0.3
COAD	chr19	47360057	Silent	rs760201365	F454F	0.96
ESCA	chr19	47372848	Silent	rs145460110	A629A	0.43
ESCA	chr19	47380987	Missense_Mutation	novel	L1052I	0.48
GBM	chr19	47359987	Missense_Mutation	novel	P431H	0.08
GBM	chr19	47381263	Silent	rs146403098	T1079T	0.38
GBM	chr19	47379757	Silent	NA	S918S	0.26
GBM	chr19	47379738	Missense_Mutation	novel	D912G	0.5
GBM	chr19	47353724	Missense_Mutation	novel	Y232H	0.29
GBM	chr19	47372801	Missense_Mutation	rs746433421	V614I	0.43	HA2
GBM	chr19	47357937	Silent	novel	L363L	0.49
GBM	chr19	47355213	Missense_Mutation	rs141590528	V294I	0.06
GBM	chr19	47353608	Missense_Mutation	novel	T193S	0.2
GBM	chr19	47376496	Silent	rs571902778	F845F	0.36
GBM	chr19	47353143	Missense_Mutation	novel	L38P	0.14
HNSC	chr19	47380854	Silent	novel	V1007V	0.41
HNSC	chr19	47353356	Missense_Mutation	novel	S109F	0.16
HNSC	chr19	47353167	Missense_Mutation	NA	E46G	0.31
HNSC	chr19	47353482	Missense_Mutation	rs149967464	R151H	0.33
HNSC	chr19	47375684	Silent	novel	G761G	0.33
HNSC	chr19	47380863	Missense_Mutation	novel	M1010I	0.19
HNSC	chr19	47360046	Missense_Mutation	novel	G451W	0.23
HNSC	chr19	47362613	Missense_Mutation	novel	A505T	0.15
KIRC	chr19	47353305	Missense_Mutation	rs767150327	A92V	0.17
KIRP	chr19	47353569	Missense_Mutation	NA	V180A	0.37
LGG	chr19	47379946	Silent	novel	A981A	0.08
LGG	chr19	47376054	Missense_Mutation	novel	A813V	0.38
LIHC	chr19	47362621	Silent	novel	S507S	0.47
LIHC	chr19	47352929	5'UTR	novel		0.42
LIHC	chr19	47358097	Silent	NA	L417L	0.44
LIHC	chr19	47382194	3'UTR	novel		0.4
LIHC	chr19	47382162	3'UTR	novel		0.25
LUAD	chr19	47367085	Silent	NA	A566A	0.3
LUAD	chr19	47381262	Missense_Mutation	rs538434908	T1079M	0.21
LUAD	chr19	47372891	Missense_Mutation	novel	T644S	0.92	HA2
LUAD	chr19	47379922	Silent	novel	T973T	0.22
LUAD	chr19	47355200	Missense_Mutation	novel	D289E	0.09
LUAD	chr19	47373667	Silent	NA	L677L	0.48
LUAD	chr19	47367083	Missense_Mutation	novel	A566S	0.17	HA2
LUAD	chr19	47367072	Missense_Mutation	NA	R562L	0.2	HA2
LUAD	chr19	47376035	Missense_Mutation	novel	G807C	0.62
LUAD	chr19	47353502	Nonsense_Mutation	NA	E158*	0.32
LUAD	chr19	47379793	Silent	novel	L930L	0.1
LUAD	chr19	47362616	Nonsense_Mutation	NA	E506*	0.3
LUAD	chr19	47353323	Missense_Mutation	rs747233116	R98H	0.12
LUAD	chr19	47375580	Nonsense_Mutation	novel	Q727*	0.67
LUAD	chr19	47381324	Missense_Mutation	NA	G1100W	0.47
LUAD	chr19	47353261	Frame_Shift_Del	novel	*K78Gfs54**	0.19
LUAD	chr19	47372893	Silent	NA	T644T	0.43
LUAD	chr19	47379874	Missense_Mutation	NA	Q957H	0.23
LUSC	chr19	47355332	Silent	novel	G333G	0.64
LUSC	chr19	47366998	Silent	rs768544760	V537V	0.22
LUSC	chr19	47355239	Silent	NA	R302R	0.45
LUSC	chr19	47372740	Silent	novel	L593L	0.15
LUSC	chr19	47376448	Frame_Shift_Del	novel	*H830Tfs43**	0.3
LUSC	chr19	47375954	Missense_Mutation	novel	A780S	0.18
LUSC	chr19	47352957	5'UTR	novel		0.72
LUSC	chr19	47357997	Silent	novel	V383V	0.15
LUSC	chr19	47357937	Silent	novel	L363L	0.2
LUSC	chr19	47353077	Frame_Shift_Ins	novel	*R17Pfs30**	0.3
LUSC	chr19	47375999	Missense_Mutation	rs775749081	E795K	0.41
LUSC	chr19	47357972	Missense_Mutation	novel	P375H	0.15
LUSC	chr19	47373639	Missense_Mutation	novel	R668L	0.25
OV	chr19	47353185	Missense_Mutation	NA	Q52L	0.21
OV	chr19	47358121	Splice_Site	NA	X424_splice	0.93
OV	chr19	47353420	Silent	novel	V130V	0.12
OV	chr19	47372788	Silent	novel	A609A	0.24
OV	chr19	47353477	Missense_Mutation	NA	F149L	0.19
OV	chr19	47372799	Missense_Mutation	novel	S613T	0.27	HA2
OV	chr19	47353557	Missense_Mutation	NA	K176T	0.13
PAAD	chr19	47353283	Nonsense_Mutation	novel	Q85*	0.04
PAAD	chr19	47362636	Silent	rs138426511	F512F	0.23
PAAD	chr19	47367101	Missense_Mutation	novel	A572T	0.18	HA2
PRAD	chr19	47372825	Missense_Mutation	rs146830596	A622T	0.12	HA2
PRAD	chr19	47381262	Missense_Mutation	rs538434908	T1079M	0.13
PRAD	chr19	47353568	Missense_Mutation	NA	V180M	0.2
PRAD	chr19	47382172	3'UTR	novel		0.29
PRAD	chr19	47373671	Missense_Mutation	rs771101635	E679K	0.33
PRAD	chr19	47381195	Missense_Mutation	novel	D1057N	0.35
READ	chr19	47375654	Silent	rs201215124	D751D	0.39
READ	chr19	47353008	5'UTR	novel		0.26
READ	chr19	47355277	Missense_Mutation	NA	N315S	0.32
SARC	chr19	47355041	Splice_Region	rs753572284	V236V	0.24
SARC	chr19	47362632	Missense_Mutation	rs202227021	A511D	0.41
SKCM	chr19	47379711	Missense_Mutation	NA	S903F	0.13
SKCM	chr19	47376983	Intron	novel		0.36
SKCM	chr19	47353522	Silent	rs148693538	I164I	0.2
SKCM	chr19	47355082	Missense_Mutation	NA	T250I	0.14
SKCM	chr19	47353659	Missense_Mutation	novel	T210I	0.25
SKCM	chr19	47353660	Silent	novel	T210T	0.25
SKCM	chr19	47372810	Missense_Mutation	NA	P617S	0.34	HA2
SKCM	chr19	47353432	Silent	rs768564171	R134R	0.45
SKCM	chr19	47355132	Missense_Mutation	NA	E267K	0.41
SKCM	chr19	47353044	Missense_Mutation	NA	R5K	0.35
SKCM	chr19	47353265	Missense_Mutation	NA	E79K	0.45
SKCM	chr19	47362579	Silent	NA	G493G	0.18
SKCM	chr19	47377143	Silent	rs748684125	F881F	0.34
SKCM	chr19	47367026	Missense_Mutation	NA	E547K	0.27
SKCM	chr19	47377195	Missense_Mutation	rs771665841	P899S	0.29
SKCM	chr19	47355126	Nonsense_Mutation	NA	Q265*	0.1
SKCM	chr19	47382065	Silent	NA	F1128F	0.42
SKCM	chr19	47376538	Silent	NA	A859A	0.5
SKCM	chr19	47367025	Silent	rs565413804	I546I	0.65
SKCM	chr19	47357958	Silent	NA	D370D	0.41
SKCM	chr19	47381237	Missense_Mutation	novel	H1071N	0.42
SKCM	chr19	47381238	Missense_Mutation	novel	H1071P	0.41
SKCM	chr19	47357981	Missense_Mutation	NA	R378L	0.26
SKCM	chr19	47355095	Silent	NA	F254F	0.42
SKCM	chr19	47357934	Silent	novel	F362F	0.15
SKCM	chr19	47375523	Missense_Mutation	novel	S708C	0.4
SKCM	chr19	47373618	Missense_Mutation	novel	R661K	0.56
SKCM	chr19	47358021	Silent	novel	I391I	0.17
SKCM	chr19	47367120	Missense_Mutation	NA	S578F	0.23	HA2
SKCM	chr19	47353037	Missense_Mutation	NA	P3S	0.4
SKCM	chr19	47376058	Silent	novel	V814V	0.49
SKCM	chr19	47376059	Missense_Mutation	novel	P815S	0.49
SKCM	chr19	47382065	Silent	NA	F1128F	0.33
SKCM	chr19	47377203	Silent	novel	L901L	0.32
STAD	chr19	47367042	Missense_Mutation	novel	A552V	0.21
STAD	chr19	47355238	Missense_Mutation	rs761357245	R302Q	0.18
STAD	chr19	47355266	Silent	rs150145021	S311S	0.12
STAD	chr19	47380957	Missense_Mutation	rs148368794	A1042T	0.2
STAD	chr19	47381258	Missense_Mutation	novel	L1078I	0.07
STAD	chr19	47380891	Frame_Shift_Ins	novel	*H1022Pfs24**	0.21
STAD	chr19	47380831	Missense_Mutation	rs199881839	R1000W	0.19
STAD	chr19	47382140	3'UTR	rs370718716		0.31
STAD	chr19	47362585	Silent	novel	T495T	0.31
STAD	chr19	47379849	Missense_Mutation	rs372536674	R949H	0.19
STAD	chr19	47381253	Missense_Mutation	rs200644278	A1076V	0.42
STAD	chr19	47382038	Silent	novel	Y1119Y	0.46
STAD	chr19	47377173	Silent	rs374278350	Y891Y	0.39
STAD	chr19	47355055	Missense_Mutation	novel	R241H	0.25
STAD	chr19	47379759	Missense_Mutation	rs140449776	R919H	0.21
STAD	chr19	47376056	Missense_Mutation	rs749202413	V814I	0.21
STAD	chr19	47353226	Missense_Mutation	rs553380305	R66C	0.24
STAD	chr19	47353654	Silent	rs375500888	A208A	0.3
STAD	chr19	47353423	Silent	NA	A131A	0.09
STAD	chr19	47380835	Missense_Mutation	rs202114364	R1001Q	0.37
STAD	chr19	47355266	Silent	rs150145021	S311S	0.55
STAD	chr19	47376550	Silent	rs183232354	D863D	0.47
STAD	chr19	47379842	Missense_Mutation	rs199664950	R947C	0.2
STAD	chr19	47355265	Missense_Mutation	NA	S311L	0.2
STAD	chr19	47372792	Missense_Mutation	rs199807432	A611T	0.24	HA2
STAD	chr19	47381279	Missense_Mutation	NA	A1085T	0.3
UCEC	chr19	47367055	Silent	rs779830950	T556T	0.51
UCEC	chr19	47379954	Missense_Mutation	NA	S984N	0.46
UCEC	chr19	47362638	Frame_Shift_Del	novel	*Y515Tfs18**	0.5
UCEC	chr19	47359981	Missense_Mutation	novel	A429V	0.35
UCEC	chr19	47353331	Missense_Mutation	rs151128528	D101N	0.51
UCEC	chr19	47353091	Missense_Mutation	rs764848134	E21K	0.34
UCEC	chr19	47372820	Missense_Mutation	rs201148024	R620H	0.36	HA2
UCEC	chr19	47353543	Silent	novel	I171I	0.44
UCEC	chr19	47362521	Missense_Mutation	novel	R474Q	0.43
UCEC	chr19	47379922	Silent	rs116233954	T973T	0.19
UCEC	chr19	47380820	Missense_Mutation	novel	P996H	0.08
UCEC	chr19	47382064	Missense_Mutation	NA	F1128S	0.51
UCEC	chr19	47355198	Missense_Mutation	rs199846132	D289N	0.23
UCEC	chr19	47362620	Missense_Mutation	rs374782101	S507L	0.16
UCEC	chr19	47376081	Missense_Mutation	rs145629927	R822Q	0.44
UCEC	chr19	47353059	Missense_Mutation	novel	R10K	0.41
UCEC	chr19	47355350	Splice_Region	rs368953997	T339T	0.22
UCEC	chr19	47377102	Missense_Mutation	rs760575695	D868N	0.42
UCEC	chr19	47358013	Missense_Mutation	novel	A389T	0.25
UCEC	chr19	47357995	Missense_Mutation	rs144919221	V383I	0.49
UCEC	chr19	47377169	Missense_Mutation	rs145900546	P890L	0.35
UCEC	chr19	47367057	Missense_Mutation	novel	A557V	0.22
UCEC	chr19	47379900	Missense_Mutation	novel	L966P	0.45
UCEC	chr19	47380829	Missense_Mutation	novel	L999P	0.22
UCEC	chr19	47382035	Silent	novel	P1118P	0.22
UCEC	chr19	47353569	Missense_Mutation	NA	V180A	0.22
UCEC	chr19	47355070	Missense_Mutation	rs781197137	R246H	0.52
UCEC	chr19	47355198	Missense_Mutation	rs199846132	D289N	0.26
UCEC	chr19	47375602	Missense_Mutation	rs200092838	R734H	0.38
UCEC	chr19	47372829	Missense_Mutation	novel	Q623P	0.14	HA2
UCEC	chr19	47353337	Missense_Mutation	rs199965702	R103C	0.36
UCEC	chr19	47379770	Missense_Mutation	rs762160827	D923N	0.41
UCEC	chr19	47360058	Missense_Mutation	rs763768330	V455I	0.58
UCEC	chr19	47373642	Missense_Mutation	rs755510811	R669H	0.46
UCEC	chr19	47376081	Missense_Mutation	rs145629927	R822Q	0.57
UCEC	chr19	47382054	Missense_Mutation	novel	G1125R	0.46
UCEC	chr19	47353377	Missense_Mutation	rs753810442	R116Q	0.5
UCEC	chr19	47382063	Nonsense_Mutation	novel	F1128*	0.07
UCEC	chr19	47382065	Missense_Mutation	novel	F1128L	0.05
UCEC	chr19	47362520	Missense_Mutation	rs769467907	R474W	0.37
UCEC	chr19	47353140	Missense_Mutation	rs779113700	R37H	0.41
UCEC	chr19	47382052	Missense_Mutation	novel	C1124Y	0.47
UCEC	chr19	47353291	Missense_Mutation	novel	K87N	0.22
UCEC	chr19	47360059	Missense_Mutation	novel	V455A	0.66
UCEC	chr19	47372801	Missense_Mutation	rs746433421	V614I	0.47	HA2
UCEC	chr19	47375619	Missense_Mutation	rs533613084	R740W	0.56
UCEC	chr19	47376550	Silent	rs183232354	D863D	0.37
UCEC	chr19	47353333	Missense_Mutation	NA	D101E	0.15
UCEC	chr19	47355267	Missense_Mutation	novel	A312S	0.33
UCEC	chr19	47355198	Missense_Mutation	rs199846132	D289N	0.29
UCEC	chr19	47367009	Missense_Mutation	novel	R541Q	0.39
UCEC	chr19	47353615	Silent	novel	V195V	0.21
UCEC	chr19	47376454	Silent	rs753543027	T831T	0.3
UCEC	chr19	47377101	Splice_Region	rs374857096	D867D	0.47
UCEC	chr19	47379815	Nonsense_Mutation	rs146308675	R938*	0.3
UCEC	chr19	47353182	Missense_Mutation	rs766834146	R51H	0.27
UCEC	chr19	47362637	Missense_Mutation	rs748916222	A513T	0.09
UCEC	chr19	47353344	Missense_Mutation	novel	R105H	0.49
UCEC	chr19	47375673	Frame_Shift_Ins	rs763046010	*G761Rfs4**	0.47
UCEC	chr19	47380926	Silent	NA	T1031T	0.21
UCEC	chr19	47360058	Missense_Mutation	rs763768330	V455I	0.41
UCEC	chr19	47375673	Frame_Shift_Ins	rs763046010	*G761Rfs4**	0.38
UCEC	chr19	47353136	Missense_Mutation	rs748157892	R36C	0.26
UCEC	chr19	47375673	Frame_Shift_Ins	rs763046010	*G761Rfs4**	0.45
UCEC	chr19	47375654	Silent	rs201215124	D751D	0.15
UCEC	chr19	47377145	Missense_Mutation	NA	V882A	0.17
UCEC	chr19	47359995	Missense_Mutation	novel	R434W	0.44
UCEC	chr19	47355225	Missense_Mutation	rs147061911	L298M	0.24
UCEC	chr19	47375673	Frame_Shift_Ins	rs763046010	*G761Rfs4**	0.41
UCEC	chr19	47380891	Frame_Shift_Ins	novel	*H1022Pfs24**	0.4
UCEC	chr19	47376520	Silent	novel	H853H	0.47
UCEC	chr19	47380957	Missense_Mutation	rs148368794	A1042T	0.27
UCEC	chr19	47353238	Missense_Mutation	novel	F70I	0.4
UCEC	chr19	47381279	Missense_Mutation	NA	A1085T	0.38
UCEC	chr19	47353198	Silent	novel	E56E	0.39
UCEC	chr19	47373638	Missense_Mutation	rs372106994	R668C	0.43
UCEC	chr19	47353164	Missense_Mutation	rs200529916	R45H	0.13
UCS	chr19	47353300	Silent	novel	I90I	0.34

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	DEL	0.0983	0.027508
KIRP	DEL	0.0486	0.054726
LUAD	DEL	0.2674	1.5526e-05
LUSC	DEL	0.2196	1.1877e-06
OV	DEL	0.4819	2.441e-17
PAAD	DEL	0.0815	0.035089
READ	DEL	0.097	0.23023
TGCT	DEL	0.2867	0.0046229
UCS	DEL	0.1964	0.12448

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00014	Kaplan-Meier Survival Analysis
SARC	0.00064	Kaplan-Meier Survival Analysis
MESO	0.00022	Kaplan-Meier Survival Analysis
ACC	0.00012	Kaplan-Meier Survival Analysis
HNSC	0.0076	Kaplan-Meier Survival Analysis
SKCM	0.00027	Kaplan-Meier Survival Analysis
PRAD	0.031	Kaplan-Meier Survival Analysis
ESCA	0.023	Kaplan-Meier Survival Analysis
KIRP	0.0046	Kaplan-Meier Survival Analysis
PAAD	0.011	Kaplan-Meier Survival Analysis
BLCA	0.013	Kaplan-Meier Survival Analysis
LAML	0.033	Kaplan-Meier Survival Analysis
LIHC	0.00011	Kaplan-Meier Survival Analysis
LGG	0.00011	Kaplan-Meier Survival Analysis
UVM	0.014	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000134815 (Gene tree)
Gene ID: 9704
Gene Symbol: DHX34
Alias: KIAA0134|DDX34
Full Name: DExH-box helicase 34
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 33,424 bases
Position: chr19:47,349,281-47,382,704
Accession: 16719
RBP type: canonical RBP
Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. It is mapped to the glioma 19q tumor suppressor region and is a tumor suppressor candidate gene. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000331907	HA2	PF04408.23	1.4e-16	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000471451	DHX34-203	426	-	-	- (aa)	-	-
ENST00000486327	DHX34-204	2897	-	-	- (aa)	-	-
ENST00000328771	DHX34-201	4372	XM_005259443	ENSP00000331907	1143 (aa)	XP_005259500	Q14147
ENST00000460681	DHX34-202	1838	-	ENSP00000418656	272 (aa)	-	H7C504

Gene Model

Click here to download ENSG00000134815's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000134815's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000134815	DHX34	53	32.357	ENSG00000174953	DHX36	95	42.105
ENSG00000134815	DHX34	50	34.512	ENSG00000101452	DHX35	85	34.512

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000134815	DHX34	98	61.946	ENSAPOG00000012602	dhx34	99	61.685	Acanthochromis_polyacanthus
ENSG00000134815	DHX34	100	86.835	ENSAMEG00000008270	DHX34	100	86.748	Ailuropoda_melanoleuca
ENSG00000134815	DHX34	98	60.771	ENSACIG00000024038	dhx34	99	60.420	Amphilophus_citrinellus
ENSG00000134815	DHX34	98	61.876	ENSAOCG00000006310	dhx34	99	61.639	Amphiprion_ocellaris
ENSG00000134815	DHX34	98	62.009	ENSAPEG00000013725	dhx34	99	61.639	Amphiprion_percula
ENSG00000134815	DHX34	98	60.157	ENSATEG00000009105	dhx34	99	60.244	Anabas_testudineus
ENSG00000134815	DHX34	90	63.821	ENSACAG00000004112	DHX34	97	67.500	Anolis_carolinensis
ENSG00000134815	DHX34	100	95.629	ENSANAG00000038287	DHX34	100	95.017	Aotus_nancymaae
ENSG00000134815	DHX34	98	60.911	ENSACLG00000021819	dhx34	99	60.297	Astatotilapia_calliptera
ENSG00000134815	DHX34	98	60.417	ENSAMXG00000019705	dhx34	99	60.417	Astyanax_mexicanus
ENSG00000134815	DHX34	100	88.482	ENSBTAG00000006848	DHX34	100	88.394	Bos_taurus
ENSG00000134815	DHX34	90	32.530	WBGene00021365	smgl-2	81	42.248	Caenorhabditis_elegans
ENSG00000134815	DHX34	100	95.629	ENSCJAG00000011504	DHX34	98	95.192	Callithrix_jacchus
ENSG00000134815	DHX34	100	88.918	ENSCAFG00000004170	DHX34	100	88.317	Canis_familiaris
ENSG00000134815	DHX34	100	88.743	ENSCAFG00020001163	DHX34	100	88.743	Canis_lupus_dingo
ENSG00000134815	DHX34	100	88.666	ENSCHIG00000024526	DHX34	100	88.579	Capra_hircus
ENSG00000134815	DHX34	100	84.965	ENSTSYG00000031168	DHX34	94	91.463	Carlito_syrichta
ENSG00000134815	DHX34	100	84.462	ENSCAPG00000014599	DHX34	100	84.809	Cavia_aperea
ENSG00000134815	DHX34	100	85.279	ENSCPOG00000006510	DHX34	100	85.105	Cavia_porcellus
ENSG00000134815	DHX34	100	94.672	ENSCCAG00000028675	DHX34	100	94.585	Cebus_capucinus
ENSG00000134815	DHX34	100	94.934	ENSCATG00000032316	DHX34	100	94.934	Cercocebus_atys
ENSG00000134815	DHX34	100	86.794	ENSCLAG00000000906	DHX34	100	86.707	Chinchilla_lanigera
ENSG00000134815	DHX34	100	94.751	ENSCSAG00000002965	DHX34	100	94.751	Chlorocebus_sabaeus
ENSG00000134815	DHX34	96	49.820	ENSCING00000004681	-	99	49.731	Ciona_intestinalis
ENSG00000134815	DHX34	96	50.901	ENSCSAVG00000009685	-	100	69.118	Ciona_savignyi
ENSG00000134815	DHX34	100	97.025	ENSCANG00000037215	DHX34	100	97.025	Colobus_angolensis_palliatus
ENSG00000134815	DHX34	98	60.366	ENSCSEG00000007100	dhx34	99	60.192	Cynoglossus_semilaevis
ENSG00000134815	DHX34	98	61.431	ENSCVAG00000002423	dhx34	99	61.518	Cyprinodon_variegatus
ENSG00000134815	DHX34	98	59.413	ENSDARG00000061168	dhx34	99	59.413	Danio_rerio
ENSG00000134815	DHX34	100	77.135	ENSDNOG00000031738	DHX34	100	77.049	Dasypus_novemcinctus
ENSG00000134815	DHX34	100	82.537	ENSDORG00000008437	Dhx34	100	82.537	Dipodomys_ordii
ENSG00000134815	DHX34	88	44.089	FBgn0052533	CG32533	90	44.530	Drosophila_melanogaster
ENSG00000134815	DHX34	63	85.906	ENSETEG00000013686	-	63	85.906	Echinops_telfairi
ENSG00000134815	DHX34	97	53.798	ENSEBUG00000014272	dhx34	99	53.970	Eptatretus_burgeri
ENSG00000134815	DHX34	100	87.631	ENSEASG00005004155	DHX34	100	87.979	Equus_asinus_asinus
ENSG00000134815	DHX34	100	87.631	ENSECAG00000011354	DHX34	100	89.647	Equus_caballus
ENSG00000134815	DHX34	93	85.433	ENSEEUG00000009027	DHX34	85	95.192	Erinaceus_europaeus
ENSG00000134815	DHX34	98	61.021	ENSELUG00000021992	dhx34	95	65.047	Esox_lucius
ENSG00000134815	DHX34	100	88.189	ENSFCAG00000006144	DHX34	100	88.189	Felis_catus
ENSG00000134815	DHX34	84	82.029	ENSFDAG00000014928	DHX34	97	82.029	Fukomys_damarensis
ENSG00000134815	DHX34	97	60.789	ENSFHEG00000000517	dhx34	99	60.877	Fundulus_heteroclitus
ENSG00000134815	DHX34	98	61.106	ENSGMOG00000013400	dhx34	99	61.018	Gadus_morhua
ENSG00000134815	DHX34	98	60.649	ENSGACG00000013085	dhx34	100	79.710	Gasterosteus_aculeatus
ENSG00000134815	DHX34	67	71.851	ENSGAGG00000008776	DHX34	94	71.851	Gopherus_agassizii
ENSG00000134815	DHX34	100	94.838	ENSGGOG00000010037	DHX34	100	94.226	Gorilla_gorilla
ENSG00000134815	DHX34	98	61.033	ENSHBUG00000009820	dhx34	99	60.595	Haplochromis_burtoni
ENSG00000134815	DHX34	100	87.249	ENSHGLG00000004917	DHX34	100	87.162	Heterocephalus_glaber_female
ENSG00000134815	DHX34	100	87.424	ENSHGLG00100017146	DHX34	100	87.336	Heterocephalus_glaber_male
ENSG00000134815	DHX34	98	60.609	ENSHCOG00000017578	dhx34	99	60.609	Hippocampus_comes
ENSG00000134815	DHX34	98	57.629	ENSIPUG00000000655	Dhx34	99	57.629	Ictalurus_punctatus
ENSG00000134815	DHX34	100	90.576	ENSSTOG00000015831	DHX34	100	90.227	Ictidomys_tridecemlineatus
ENSG00000134815	DHX34	98	57.573	ENSLBEG00000018430	dhx34	99	57.401	Labrus_bergylta
ENSG00000134815	DHX34	93	63.035	ENSLACG00000014421	DHX34	99	65.465	Latimeria_chalumnae
ENSG00000134815	DHX34	98	62.781	ENSLOCG00000014928	dhx34	98	62.190	Lepisosteus_oculatus
ENSG00000134815	DHX34	100	83.930	ENSLAFG00000003186	DHX34	100	83.930	Loxodonta_africana
ENSG00000134815	DHX34	100	97.113	ENSMFAG00000032991	DHX34	100	97.113	Macaca_fascicularis
ENSG00000134815	DHX34	100	97.375	ENSMMUG00000009275	DHX34	100	97.375	Macaca_mulatta
ENSG00000134815	DHX34	100	97.113	ENSMNEG00000038649	DHX34	100	97.113	Macaca_nemestrina
ENSG00000134815	DHX34	93	96.457	ENSMLEG00000041860	DHX34	100	98.007	Mandrillus_leucophaeus
ENSG00000134815	DHX34	97	60.175	ENSMAMG00000014106	dhx34	97	60.174	Mastacembelus_armatus
ENSG00000134815	DHX34	98	60.911	ENSMZEG00005024153	dhx34	99	60.297	Maylandia_zebra
ENSG00000134815	DHX34	100	87.631	ENSMAUG00000013394	Dhx34	100	87.631	Mesocricetus_auratus
ENSG00000134815	DHX34	100	89.248	ENSMICG00000011585	DHX34	100	89.248	Microcebus_murinus
ENSG00000134815	DHX34	99	87.688	ENSMOCG00000016843	Dhx34	100	87.282	Microtus_ochrogaster
ENSG00000134815	DHX34	98	60.702	ENSMMOG00000001357	dhx34	99	60.561	Mola_mola
ENSG00000134815	DHX34	99	73.818	ENSMODG00000008850	DHX34	99	73.818	Monodelphis_domestica
ENSG00000134815	DHX34	98	60.105	ENSMALG00000008883	dhx34	99	59.861	Monopterus_albus
ENSG00000134815	DHX34	100	87.990	MGP_CAROLIEiJ_G0029226	Dhx34	100	87.990	Mus_caroli
ENSG00000134815	DHX34	100	87.467	ENSMUSG00000006019	Dhx34	100	87.467	Mus_musculus
ENSG00000134815	DHX34	100	87.391	MGP_PahariEiJ_G0021082	Dhx34	100	87.652	Mus_pahari
ENSG00000134815	DHX34	100	87.990	MGP_SPRETEiJ_G0030305	Dhx34	100	87.990	Mus_spretus
ENSG00000134815	DHX34	92	87.182	ENSMPUG00000004925	DHX34	98	87.088	Mustela_putorius_furo
ENSG00000134815	DHX34	100	88.415	ENSMLUG00000013743	DHX34	100	89.024	Myotis_lucifugus
ENSG00000134815	DHX34	100	86.725	ENSNGAG00000012974	Dhx34	100	86.463	Nannospalax_galili
ENSG00000134815	DHX34	100	94.590	ENSNLEG00000003010	DHX34	100	94.590	Nomascus_leucogenys
ENSG00000134815	DHX34	99	66.285	ENSMEUG00000005067	DHX34	99	66.197	Notamacropus_eugenii
ENSG00000134815	DHX34	89	85.235	ENSOPRG00000011872	-	89	85.235	Ochotona_princeps
ENSG00000134815	DHX34	100	84.307	ENSODEG00000006333	DHX34	100	84.220	Octodon_degus
ENSG00000134815	DHX34	98	61.072	ENSONIG00000004067	dhx34	99	60.633	Oreochromis_niloticus
ENSG00000134815	DHX34	74	63.773	ENSOANG00000000569	-	98	63.991	Ornithorhynchus_anatinus
ENSG00000134815	DHX34	100	88.364	ENSOCUG00000014005	DHX34	100	88.364	Oryctolagus_cuniculus
ENSG00000134815	DHX34	98	60.714	ENSORLG00000002308	dhx34	99	60.714	Oryzias_latipes
ENSG00000134815	DHX34	98	60.643	ENSORLG00020017122	dhx34	98	60.643	Oryzias_latipes_hni
ENSG00000134815	DHX34	98	60.730	ENSORLG00015005813	dhx34	99	60.730	Oryzias_latipes_hsok
ENSG00000134815	DHX34	98	61.780	ENSOMEG00000001279	dhx34	99	61.606	Oryzias_melastigma
ENSG00000134815	DHX34	100	90.148	ENSOGAG00000002061	DHX34	100	90.148	Otolemur_garnettii
ENSG00000134815	DHX34	90	82.041	ENSOARG00000011049	DHX34	95	87.774	Ovis_aries
ENSG00000134815	DHX34	100	95.451	ENSPPAG00000029582	DHX34	100	95.451	Pan_paniscus
ENSG00000134815	DHX34	100	88.189	ENSPPRG00000002535	DHX34	100	88.189	Panthera_pardus
ENSG00000134815	DHX34	88	85.859	ENSPTIG00000018435	DHX34	98	73.046	Panthera_tigris_altaica
ENSG00000134815	DHX34	100	99.300	ENSPTRG00000011207	DHX34	100	99.300	Pan_troglodytes
ENSG00000134815	DHX34	100	97.375	ENSPANG00000011774	DHX34	100	97.375	Papio_anubis
ENSG00000134815	DHX34	99	61.379	ENSPKIG00000013394	dhx34	99	61.578	Paramormyrops_kingsleyae
ENSG00000134815	DHX34	97	61.464	ENSPMGG00000016033	dhx34	99	61.376	Periophthalmus_magnuspinnatus
ENSG00000134815	DHX34	100	88.322	ENSPEMG00000017613	Dhx34	100	88.322	Peromyscus_maniculatus_bairdii
ENSG00000134815	DHX34	95	57.117	ENSPMAG00000000368	dhx34	99	57.455	Petromyzon_marinus
ENSG00000134815	DHX34	98	74.097	ENSPCIG00000000889	DHX34	99	74.097	Phascolarctos_cinereus
ENSG00000134815	DHX34	98	61.082	ENSPFOG00000011417	dhx34	99	60.783	Poecilia_formosa
ENSG00000134815	DHX34	98	60.366	ENSPLAG00000021500	dhx34	99	60.121	Poecilia_latipinna
ENSG00000134815	DHX34	98	60.659	ENSPMEG00000008135	dhx34	99	60.783	Poecilia_mexicana
ENSG00000134815	DHX34	98	60.767	ENSPREG00000016403	dhx34	99	60.593	Poecilia_reticulata
ENSG00000134815	DHX34	100	97.725	ENSPPYG00000010172	DHX34	100	97.725	Pongo_abelii
ENSG00000134815	DHX34	89	82.699	ENSPCAG00000003843	DHX34	89	82.699	Procavia_capensis
ENSG00000134815	DHX34	100	90.734	ENSPCOG00000027801	DHX34	100	90.734	Propithecus_coquereli
ENSG00000134815	DHX34	90	82.520	ENSPVAG00000004017	DHX34	100	85.932	Pteropus_vampyrus
ENSG00000134815	DHX34	98	60.999	ENSPNYG00000007967	dhx34	99	60.384	Pundamilia_nyererei
ENSG00000134815	DHX34	98	61.438	ENSPNAG00000015028	dhx34	99	61.438	Pygocentrus_nattereri
ENSG00000134815	DHX34	96	87.579	ENSRNOG00000047575	Dhx34	99	87.851	Rattus_norvegicus
ENSG00000134815	DHX34	100	95.308	ENSRBIG00000037382	DHX34	100	95.308	Rhinopithecus_bieti
ENSG00000134815	DHX34	100	96.675	ENSRROG00000042872	DHX34	100	96.675	Rhinopithecus_roxellana
ENSG00000134815	DHX34	100	96.325	ENSSBOG00000026147	DHX34	100	96.642	Saimiri_boliviensis_boliviensis
ENSG00000134815	DHX34	98	62.608	ENSSFOG00015023082	dhx34	99	62.629	Scleropages_formosus
ENSG00000134815	DHX34	98	60.764	ENSSMAG00000000815	dhx34	99	60.677	Scophthalmus_maximus
ENSG00000134815	DHX34	89	62.909	ENSSDUG00000021018	dhx34	95	62.813	Seriola_dumerili
ENSG00000134815	DHX34	98	60.643	ENSSLDG00000005497	dhx34	99	60.643	Seriola_lalandi_dorsalis
ENSG00000134815	DHX34	75	71.827	ENSSPUG00000012308	DHX34	97	71.827	Sphenodon_punctatus
ENSG00000134815	DHX34	97	59.631	ENSSPAG00000023353	dhx34	97	62.386	Stegastes_partitus
ENSG00000134815	DHX34	93	79.447	ENSSSCG00000003114	DHX34	97	83.770	Sus_scrofa
ENSG00000134815	DHX34	98	58.115	ENSTRUG00000010539	dhx34	99	58.028	Takifugu_rubripes
ENSG00000134815	DHX34	98	60.105	ENSTNIG00000016288	dhx34	100	78.744	Tetraodon_nigroviridis
ENSG00000134815	DHX34	83	94.190	ENSTBEG00000007047	DHX34	83	94.190	Tupaia_belangeri
ENSG00000134815	DHX34	100	85.004	ENSTTRG00000002257	DHX34	100	84.830	Tursiops_truncatus
ENSG00000134815	DHX34	100	87.271	ENSUAMG00000020189	DHX34	100	87.184	Ursus_americanus
ENSG00000134815	DHX34	100	88.656	ENSVVUG00000023515	DHX34	100	88.656	Vulpes_vulpes
ENSG00000134815	DHX34	98	62.191	ENSXETG00000012176	dhx34	99	62.102	Xenopus_tropicalis
ENSG00000134815	DHX34	98	60.786	ENSXCOG00000009309	dhx34	99	60.611	Xiphophorus_couchianus
ENSG00000134815	DHX34	98	60.664	ENSXMAG00000007699	dhx34	99	60.330	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	21873635.	IBA	Process
GO:0000956	nuclear-transcribed mRNA catabolic process	23828042.	IMP	Process
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0016020	membrane	19946888.	HDA	Component
GO:0034459	ATP-dependent 3'-5' RNA helicase activity	21873635.	IBA	Function
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	23828042.	IMP	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.