EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
23340300	Rab25 regulates invasion and metastasis in head and neck cancer.	Clin Cancer Res	2013 Mar 15	Amornphimoltham P	doi: 10.1158/1078-0432.CCR-12-2858
17925226	Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments.	Dev Cell	2007 Oct	Caswell PT	-
22991305	Rab25 is a tumor suppressor gene with antiangiogenic and anti-invasive activities in esophageal squamous cell carcinoma.	Cancer Res	2012 Nov 15	Tong M	doi: 10.1158/0008-5472.CAN-12-1269
26692100	Overexpression of Rab25 promotes hepatocellular carcinoma cell proliferation and invasion.	Tumour Biol	2016 Jun	Geng D	doi: 10.1007/s13277-015-4606-5
28281975	Knockdown of Ras-Related Protein 25 (Rab25) Inhibits the In Vitro Cytotoxicity and In Vivo Antitumor Activity of Human Glioblastoma Multiforme Cells.	Oncol Res	2017 Mar 13	Ding B	doi: 10.3727/096504016X14736286083065.
22613965	The action of small GTPases Rab11 and Rab25 in vesicle trafficking during cell migration.	Cell Physiol Biochem	2012	Kessler D	doi: 10.1159/000295249
20197623	Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas.	J Clin Invest	2010 Mar	Nam KT	doi: 10.1172/JCI40728
28612496	RIN1 promotes renal cell carcinoma malignancy by activating EGFR signaling through Rab25.	Cancer Sci	2017 Aug	Feng ZH	doi: 10.1111/cas.13297
27259233	Rab25 acts as an oncogene in luminal B breast cancer and is causally associated with Snail driven EMT.	Oncotarget	2016 Jun 28	Mitra S	doi: 10.18632/oncotarget.9730.
17393986	Knockdown of RAB25 expression by RNAi inhibits growth of human epithelial ovarian cancer cells in vitro and in vivo.	Pathology	2006 Dec	Fan Y	-
23030522	Increased Rab25 expression is not correlated with peritoneal metastasis of ovarian cancers.	Cancer Invest	2012 Nov	Zhao M	doi: 10.3109/07357907.2012.727935
23722651	Overexpression of Rab25 contributes to metastasis of bladder cancer through induction of epithelial-mesenchymal transition and activation of Akt/GSK-3β/Snail signaling.	Carcinogenesis	2013 Oct	Zhang J	doi: 10.1093/carcin/bgt187
22253197	Rab25 increases cellular ATP and glycogen stores protecting cancer cells from bioenergetic stress.	EMBO Mol Med	2012 Feb	Cheng KW	doi: 10.1002/emmm.201100193
22644676	Increased expression of Rab25 in breast cancer correlates with lymphatic metastasis.	Tumour Biol	2012 Oct	Yin YX	doi: 10.1007/s13277-012-0412-5
19795443	Tumor suppressor function of Rab25 in triple-negative breast cancer.	Int J Cancer	2010 Jun 15	Cheng JM	doi: 10.1002/ijc.24900.
26967059	Hypoxia-inducible factor 1 alpha is required for the tumourigenic and aggressive phenotype associated with Rab25 expression in ovarian cancer.	Oncotarget	2016 Apr 19	Gomez-Roman N	doi: 10.18632/oncotarget.7998.
29524309	MiR-577 suppresses epithelial-mesenchymal transition and metastasis of breast cancer by targeting Rab25.	Thorac Cancer	2018 Apr	Yin C	doi: 10.1111/1759-7714.12612
29371698	Rab25 augments cancer cell invasiveness through a β1 integrin/EGFR/VEGF-A/Snail signaling axis and expression of fascin.	Exp Mol Med	2018 Jan 26	Jeong BY	doi: 10.1038/emm.2017.248.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr1	156068344	Missense_Mutation	novel	R105Q	0.18	MMR_HSR1
BLCA	chr1	156066005	Silent	novel	G46G	0.11
BLCA	chr1	156068340	Nonsense_Mutation	novel	E104*	0.18	MMR_HSR1
BLCA	chr1	156069713	Missense_Mutation	novel	S159C	0.4
BLCA	chr1	156065929	Missense_Mutation	novel	S21L	0.32	MMR_HSR1
BRCA	chr1	156070406	3'UTR	novel		0.09
BRCA	chr1	156069747	Silent	NA	L170L	0.15
BRCA	chr1	156068292	Missense_Mutation	NA	A88T	0.15	MMR_HSR1
BRCA	chr1	156068393	Missense_Mutation	NA	M121I	0.14
BRCA	chr1	156070366	3'UTR	novel		0.14
CESC	chr1	156061315	5'UTR	novel		0.37
CESC	chr1	156068388	Missense_Mutation	rs368546153	V120I	0.28
COAD	chr1	156061308	5'UTR	novel		0.4
COAD	chr1	156070303	3'UTR	novel		0.6
COAD	chr1	156068405	Silent	NA	N125N	0.34
COAD	chr1	156065959	Missense_Mutation	rs566252037	R31Q	0.31	MMR_HSR1
COAD	chr1	156068423	Missense_Mutation	NA	Q131H	0.1
COAD	chr1	156065937	Missense_Mutation	NA	G24R	0.21	MMR_HSR1
COAD	chr1	156069681	Silent	NA	G148G	0.19
ESCA	chr1	156061273	5'UTR	novel		0.36
GBM	chr1	156068303	Silent	novel	V91V	0.09
GBM	chr1	156061313	5'UTR	novel		0.15
GBM	chr1	156061432	Missense_Mutation	novel	F11Y	0.13
GBM	chr1	156061434	Missense_Mutation	novel	V12F	0.13
HNSC	chr1	156061388	5'UTR	novel		0.31
HNSC	chr1	156065966	Silent	rs373021788	T33T	0.44
HNSC	chr1	156068324	Missense_Mutation	novel	Q98H	0.47	MMR_HSR1
KIRC	chr1	156070432	3'UTR	novel		0.6
LGG	chr1	156068277	Missense_Mutation	rs749179888	R83C	0.32	MMR_HSR1
LIHC	chr1	156069717	Silent	NA	T160T	0.25
LUAD	chr1	156069713	Frame_Shift_Del	novel	*T160Mfs4**	0.47
LUAD	chr1	156069747	Silent	NA	L170L	0.27
LUAD	chr1	156070200	Frame_Shift_Del	novel	*R186Wfs80**	0.09
LUAD	chr1	156070233	Missense_Mutation	novel	Q196H	0.18
LUSC	chr1	156070371	3'UTR	novel		0.54
LUSC	chr1	156070188	Silent	rs776240771	R181R	0.15
LUSC	chr1	156068280	Missense_Mutation	novel	G84C	0.31	MMR_HSR1
OV	chr1	156061328	5'UTR	novel		0.05
OV	chr1	156061330	5'UTR	novel		0.17
OV	chr1	156070225	Frame_Shift_Ins	novel	*S194Kfs?**	0.07
PAAD	chr1	156068292	Missense_Mutation	NA	A88T	0.16	MMR_HSR1
PRAD	chr1	156068343	Nonsense_Mutation	novel	R105*	0.39	MMR_HSR1
READ	chr1	156066009	Missense_Mutation	NA	E48Q	0.37	MMR_HSR1
SKCM	chr1	156065922	Missense_Mutation	rs767232901	G19S	0.22	MMR_HSR1
SKCM	chr1	156061254	5'UTR	novel		0.28
SKCM	chr1	156068384	Silent	rs752329690	I118I	0.18
SKCM	chr1	156070328	3'UTR	novel		0.32
SKCM	chr1	156070226	Missense_Mutation	novel	S194N	0.37
SKCM	chr1	156068451	Nonsense_Mutation	rs201881638	R141*	0.41
SKCM	chr1	156068427	Missense_Mutation	rs776847118	R133W	0.16
SKCM	chr1	156068294	Silent	novel	A88A	0.54
STAD	chr1	156061203	5'UTR	novel		0.2
STAD	chr1	156070202	Missense_Mutation	rs61995861	R186Q	0.68
STAD	chr1	156070223	Missense_Mutation	NA	G193D	0.24
STAD	chr1	156066041	Silent	rs201223792	T58T	0.32
UCEC	chr1	156065946	Missense_Mutation	NA	N27D	0.4	MMR_HSR1
UCEC	chr1	156070170	Silent	rs747464338	A175A	0.35
UCEC	chr1	156061347	5'UTR	novel		0.14
UCEC	chr1	156066042	Missense_Mutation	novel	A59T	0.45	MMR_HSR1
UCEC	chr1	156065959	Missense_Mutation	rs566252037	R31Q	0.12	MMR_HSR1
UCEC	chr1	156061200	5'UTR	novel		0.36
UCEC	chr1	156061263	5'UTR	novel		0.09
UCEC	chr1	156061266	5'UTR	novel		0.35
UCEC	chr1	156065997	Missense_Mutation	novel	T44A	0.15	MMR_HSR1
UCEC	chr1	156070211	Missense_Mutation	novel	A189V	0.23
UCEC	chr1	156068302	Missense_Mutation	novel	V91A	0.06	MMR_HSR1
UCEC	chr1	156068293	Missense_Mutation	novel	A88V	0.04	MMR_HSR1
UCEC	chr1	156065984	Silent	NA	H39H	0.06
UCEC	chr1	156068452	Missense_Mutation	rs767067172	R141Q	0.59
UCEC	chr1	156068452	Missense_Mutation	rs767067172	R141Q	0.34

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
DLBC	DEL	0.0208	0.0017831
ESCA	AMP	0.3967	0.0022446
KIRC	AMP	0.0928	0.059566
PAAD	AMP	0.2283	0.085665
READ	AMP	0.2667	0.025154
SKCM	AMP	0.485	9.6912e-06
TGCT	AMP	0.34	0.088103
UCEC	AMP	0.4508	1.3482e-23

Survival Analysis

Cancer	P-value	Q-value
THYM	0.028	Kaplan-Meier Survival Analysis
KIRC	0.0016	Kaplan-Meier Survival Analysis
MESO	0.01	Kaplan-Meier Survival Analysis
SKCM	0.00011	Kaplan-Meier Survival Analysis
TGCT	0.039	Kaplan-Meier Survival Analysis
PAAD	0.024	Kaplan-Meier Survival Analysis
BLCA	0.043	Kaplan-Meier Survival Analysis
LAML	0.015	Kaplan-Meier Survival Analysis
LGG	0.041	Kaplan-Meier Survival Analysis
THCA	0.042	Kaplan-Meier Survival Analysis
OV	0.02	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000132698 (Gene tree)
Gene ID: 57111
Gene Symbol: RAB25
Alias: CATX-8
Full Name: RAB25, member RAS oncogene family
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 9,355 bases
Position: chr1:156,061,160-156,070,514
Accession: 18238
RBP type: canonical RBP
Summary: The protein encoded by this gene is a member of the RAS superfamily of small GTPases. The encoded protein is involved in membrane trafficking and cell survival. This gene has been found to be a tumor suppressor and an oncogene, depending on the context. Two variants, one protein-coding and the other not, have been found for this gene. [provided by RefSeq, Nov 2015]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000354376	MMR_HSR1	PF01926.23	9.5e-07	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000463614	RAB25-202	627	-	-	- (aa)	-	-
ENST00000487325	RAB25-204	868	-	-	- (aa)	-	-
ENST00000361084	RAB25-201	1110	-	ENSP00000354376	213 (aa)	-	P57735
ENST00000497968	RAB25-205	539	-	-	- (aa)	-	-
ENST00000473336	RAB25-203	681	NR_133653	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000132698's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000132698	Parkinson Disease	4E-12	21292315

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000132698	rs61748951	1	156068267	A	Educational attainment (MTAG)	30038396	[0.019-0.037] unit decrease	0.028	EFO_0004784
ENSG00000132698	rs61748951	1	156068267	A	Educational attainment (years of education)	30038396	[0.018-0.037] unit decrease	0.0273	EFO_0004784

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000132698's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000132698	RAB25	97	68.599	ENSAPOG00000008216	rab25b	98	68.599	Acanthochromis_polyacanthus
ENSG00000132698	RAB25	98	67.464	ENSAPOG00000021268	rab25a	99	67.464	Acanthochromis_polyacanthus
ENSG00000132698	RAB25	100	97.653	ENSAMEG00000014249	RAB25	100	97.653	Ailuropoda_melanoleuca
ENSG00000132698	RAB25	98	67.464	ENSACIG00000019803	rab25a	98	67.464	Amphilophus_citrinellus
ENSG00000132698	RAB25	97	70.048	ENSACIG00000017414	rab25b	98	70.048	Amphilophus_citrinellus
ENSG00000132698	RAB25	98	68.421	ENSAOCG00000003528	rab25a	99	68.421	Amphiprion_ocellaris
ENSG00000132698	RAB25	97	70.048	ENSAOCG00000015713	rab25b	98	70.048	Amphiprion_ocellaris
ENSG00000132698	RAB25	97	70.048	ENSAPEG00000022106	rab25b	98	70.048	Amphiprion_percula
ENSG00000132698	RAB25	98	68.421	ENSAPEG00000013500	rab25a	99	68.421	Amphiprion_percula
ENSG00000132698	RAB25	97	71.014	ENSATEG00000006124	rab25b	98	71.014	Anabas_testudineus
ENSG00000132698	RAB25	98	67.943	ENSATEG00000014851	rab25a	99	67.943	Anabas_testudineus
ENSG00000132698	RAB25	100	98.122	ENSANAG00000036045	RAB25	100	98.122	Aotus_nancymaae
ENSG00000132698	RAB25	97	71.014	ENSACLG00000010251	rab25b	98	71.014	Astatotilapia_calliptera
ENSG00000132698	RAB25	98	66.986	ENSACLG00000018262	rab25a	99	66.986	Astatotilapia_calliptera
ENSG00000132698	RAB25	99	70.952	ENSAMXG00000029712	rab25b	99	70.952	Astyanax_mexicanus
ENSG00000132698	RAB25	98	68.571	ENSAMXG00000040879	rab25a	98	68.571	Astyanax_mexicanus
ENSG00000132698	RAB25	100	95.305	ENSBTAG00000018914	RAB25	100	95.305	Bos_taurus
ENSG00000132698	RAB25	100	97.653	ENSCJAG00000007715	RAB25	100	97.653	Callithrix_jacchus
ENSG00000132698	RAB25	100	96.244	ENSCAFG00000016866	RAB25	100	96.244	Canis_familiaris
ENSG00000132698	RAB25	100	96.244	ENSCAFG00020006179	RAB25	100	96.244	Canis_lupus_dingo
ENSG00000132698	RAB25	100	94.836	ENSCHIG00000018911	RAB25	100	94.836	Capra_hircus
ENSG00000132698	RAB25	100	99.061	ENSTSYG00000013028	RAB25	100	99.061	Carlito_syrichta
ENSG00000132698	RAB25	80	97.661	ENSCAPG00000006181	RAB25	99	97.661	Cavia_aperea
ENSG00000132698	RAB25	100	93.897	ENSCPOG00000002472	RAB25	100	93.897	Cavia_porcellus
ENSG00000132698	RAB25	73	98.734	ENSCCAG00000021873	RAB25	100	98.734	Cebus_capucinus
ENSG00000132698	RAB25	100	72.093	ENSCATG00000029662	RAB25	100	73.239	Cercocebus_atys
ENSG00000132698	RAB25	100	95.775	ENSCLAG00000003784	RAB25	100	95.775	Chinchilla_lanigera
ENSG00000132698	RAB25	100	100.000	ENSCSAG00000002096	RAB25	100	100.000	Chlorocebus_sabaeus
ENSG00000132698	RAB25	100	81.776	ENSCPBG00000025817	RAB25	100	81.776	Chrysemys_picta_bellii
ENSG00000132698	RAB25	93	98.492	ENSCANG00000040397	RAB25	90	98.492	Colobus_angolensis_palliatus
ENSG00000132698	RAB25	100	94.836	ENSCGRG00001017341	Rab25	100	94.836	Cricetulus_griseus_chok1gshd
ENSG00000132698	RAB25	100	94.836	ENSCGRG00000012173	Rab25	100	94.836	Cricetulus_griseus_crigri
ENSG00000132698	RAB25	97	70.048	ENSCSEG00000011982	rab25b	95	70.048	Cynoglossus_semilaevis
ENSG00000132698	RAB25	98	67.464	ENSCSEG00000017026	rab25a	99	67.464	Cynoglossus_semilaevis
ENSG00000132698	RAB25	97	71.498	ENSCVAG00000020003	rab25b	98	71.498	Cyprinodon_variegatus
ENSG00000132698	RAB25	98	66.986	ENSCVAG00000008126	-	99	66.986	Cyprinodon_variegatus
ENSG00000132698	RAB25	97	68.720	ENSDARG00000058800	rab25a	98	68.720	Danio_rerio
ENSG00000132698	RAB25	99	69.524	ENSDARG00000052954	rab25b	99	69.524	Danio_rerio
ENSG00000132698	RAB25	91	96.410	ENSDNOG00000039155	RAB25	77	96.410	Dasypus_novemcinctus
ENSG00000132698	RAB25	100	96.244	ENSDORG00000002922	Rab25	100	96.244	Dipodomys_ordii
ENSG00000132698	RAB25	100	99.061	ENSEASG00005019133	RAB25	100	99.061	Equus_asinus_asinus
ENSG00000132698	RAB25	100	99.061	ENSECAG00000023191	RAB25	100	99.061	Equus_caballus
ENSG00000132698	RAB25	99	86.607	ENSEEUG00000014804	RAB25	95	86.607	Erinaceus_europaeus
ENSG00000132698	RAB25	98	68.421	ENSELUG00000006604	rab25a	98	68.421	Esox_lucius
ENSG00000132698	RAB25	99	69.524	ENSELUG00000012060	rab25b	99	69.524	Esox_lucius
ENSG00000132698	RAB25	100	98.122	ENSFCAG00000011775	RAB25	100	98.122	Felis_catus
ENSG00000132698	RAB25	100	67.059	ENSFALG00000002597	RAB25	100	67.059	Ficedula_albicollis
ENSG00000132698	RAB25	100	97.183	ENSFDAG00000006897	RAB25	100	97.183	Fukomys_damarensis
ENSG00000132698	RAB25	97	67.150	ENSFHEG00000014186	rab25a	98	67.150	Fundulus_heteroclitus
ENSG00000132698	RAB25	97	71.498	ENSFHEG00000003018	rab25b	98	71.498	Fundulus_heteroclitus
ENSG00000132698	RAB25	78	73.054	ENSGMOG00000006444	rab25b	99	73.054	Gadus_morhua
ENSG00000132698	RAB25	90	71.204	ENSGMOG00000003577	-	96	71.204	Gadus_morhua
ENSG00000132698	RAB25	98	77.885	ENSGALG00000029812	RAB25	98	77.885	Gallus_gallus
ENSG00000132698	RAB25	97	70.531	ENSGAFG00000021724	rab25b	98	70.531	Gambusia_affinis
ENSG00000132698	RAB25	98	66.986	ENSGAFG00000011713	rab25a	93	83.117	Gambusia_affinis
ENSG00000132698	RAB25	97	71.498	ENSGACG00000013249	rab25b	97	71.498	Gasterosteus_aculeatus
ENSG00000132698	RAB25	97	67.788	ENSGACG00000004965	rab25a	98	67.788	Gasterosteus_aculeatus
ENSG00000132698	RAB25	100	81.308	ENSGAGG00000020703	RAB25	100	81.308	Gopherus_agassizii
ENSG00000132698	RAB25	100	100.000	ENSGGOG00000006821	RAB25	100	100.000	Gorilla_gorilla
ENSG00000132698	RAB25	98	66.986	ENSHBUG00000003876	rab25a	99	66.986	Haplochromis_burtoni
ENSG00000132698	RAB25	97	71.014	ENSHBUG00000009320	rab25b	98	71.014	Haplochromis_burtoni
ENSG00000132698	RAB25	100	93.897	ENSHGLG00000005517	RAB25	100	93.897	Heterocephalus_glaber_female
ENSG00000132698	RAB25	100	91.080	ENSHGLG00100016830	RAB25	100	91.080	Heterocephalus_glaber_male
ENSG00000132698	RAB25	97	66.019	ENSHCOG00000013095	rab25a	98	66.019	Hippocampus_comes
ENSG00000132698	RAB25	92	70.918	ENSHCOG00000007187	rab25b	84	70.918	Hippocampus_comes
ENSG00000132698	RAB25	99	67.619	ENSIPUG00000012218	RAB25	99	67.619	Ictalurus_punctatus
ENSG00000132698	RAB25	99	67.143	ENSIPUG00000006126	Rab25	99	67.143	Ictalurus_punctatus
ENSG00000132698	RAB25	100	98.122	ENSSTOG00000000634	RAB25	100	98.122	Ictidomys_tridecemlineatus
ENSG00000132698	RAB25	100	94.836	ENSJJAG00000021013	Rab25	100	94.836	Jaculus_jaculus
ENSG00000132698	RAB25	97	67.633	ENSKMAG00000004945	rab25a	98	67.633	Kryptolebias_marmoratus
ENSG00000132698	RAB25	97	71.014	ENSKMAG00000015488	rab25b	98	71.014	Kryptolebias_marmoratus
ENSG00000132698	RAB25	97	69.565	ENSLBEG00000016446	rab25b	98	69.565	Labrus_bergylta
ENSG00000132698	RAB25	98	64.423	ENSLBEG00000002367	rab25a	98	64.423	Labrus_bergylta
ENSG00000132698	RAB25	98	69.524	ENSLACG00000011157	RAB25	98	69.524	Latimeria_chalumnae
ENSG00000132698	RAB25	73	80.128	ENSLOCG00000008881	rab25a	91	80.128	Lepisosteus_oculatus
ENSG00000132698	RAB25	100	97.653	ENSLAFG00000009222	RAB25	100	97.653	Loxodonta_africana
ENSG00000132698	RAB25	100	100.000	ENSMFAG00000000115	RAB25	100	100.000	Macaca_fascicularis
ENSG00000132698	RAB25	100	100.000	ENSMMUG00000022306	RAB25	100	100.000	Macaca_mulatta
ENSG00000132698	RAB25	93	91.960	ENSMNEG00000004251	RAB25	95	91.960	Macaca_nemestrina
ENSG00000132698	RAB25	100	100.000	ENSMLEG00000025037	RAB25	100	100.000	Mandrillus_leucophaeus
ENSG00000132698	RAB25	97	69.082	ENSMAMG00000010297	rab25b	96	69.082	Mastacembelus_armatus
ENSG00000132698	RAB25	98	68.421	ENSMAMG00000012471	rab25a	98	68.421	Mastacembelus_armatus
ENSG00000132698	RAB25	98	66.986	ENSMZEG00005005311	rab25a	99	66.986	Maylandia_zebra
ENSG00000132698	RAB25	97	71.014	ENSMZEG00005017522	rab25b	98	71.014	Maylandia_zebra
ENSG00000132698	RAB25	100	98.122	ENSMICG00000002230	RAB25	100	98.122	Microcebus_murinus
ENSG00000132698	RAB25	99	93.333	ENSMOCG00000010953	Rab25	99	93.333	Microtus_ochrogaster
ENSG00000132698	RAB25	98	65.094	ENSMMOG00000019157	rab25a	99	65.094	Mola_mola
ENSG00000132698	RAB25	100	92.488	ENSMODG00000016955	RAB25	100	92.488	Monodelphis_domestica
ENSG00000132698	RAB25	97	69.565	ENSMALG00000004112	rab25b	98	69.565	Monopterus_albus
ENSG00000132698	RAB25	78	77.246	ENSMALG00000015154	rab25a	81	77.246	Monopterus_albus
ENSG00000132698	RAB25	100	96.244	MGP_CAROLIEiJ_G0025171	Rab25	100	96.244	Mus_caroli
ENSG00000132698	RAB25	100	95.775	ENSMUSG00000008601	Rab25	100	95.775	Mus_musculus
ENSG00000132698	RAB25	100	95.305	MGP_PahariEiJ_G0026616	Rab25	100	95.305	Mus_pahari
ENSG00000132698	RAB25	100	95.305	MGP_SPRETEiJ_G0026114	Rab25	100	95.305	Mus_spretus
ENSG00000132698	RAB25	100	92.488	ENSMPUG00000004790	RAB25	100	92.488	Mustela_putorius_furo
ENSG00000132698	RAB25	100	96.714	ENSMLUG00000010153	RAB25	100	96.714	Myotis_lucifugus
ENSG00000132698	RAB25	100	97.653	ENSNGAG00000019999	Rab25	100	97.653	Nannospalax_galili
ENSG00000132698	RAB25	98	66.986	ENSNBRG00000011607	rab25a	99	66.986	Neolamprologus_brichardi
ENSG00000132698	RAB25	100	100.000	ENSNLEG00000012323	RAB25	100	100.000	Nomascus_leucogenys
ENSG00000132698	RAB25	100	91.549	ENSMEUG00000016598	RAB25	100	91.549	Notamacropus_eugenii
ENSG00000132698	RAB25	100	93.897	ENSOPRG00000002894	RAB25	100	93.897	Ochotona_princeps
ENSG00000132698	RAB25	100	97.183	ENSODEG00000009908	RAB25	100	97.183	Octodon_degus
ENSG00000132698	RAB25	97	71.981	ENSONIG00000002284	rab25b	98	71.981	Oreochromis_niloticus
ENSG00000132698	RAB25	98	67.464	ENSONIG00000002410	rab25a	99	67.464	Oreochromis_niloticus
ENSG00000132698	RAB25	100	96.714	ENSOCUG00000005634	RAB25	100	96.714	Oryctolagus_cuniculus
ENSG00000132698	RAB25	96	69.268	ENSORLG00000016135	rab25b	98	68.367	Oryzias_latipes
ENSG00000132698	RAB25	97	67.633	ENSORLG00000012158	rab25a	98	67.633	Oryzias_latipes
ENSG00000132698	RAB25	97	69.082	ENSORLG00020013719	rab25b	98	69.082	Oryzias_latipes_hni
ENSG00000132698	RAB25	97	67.633	ENSORLG00020020811	rab25a	68	67.633	Oryzias_latipes_hni
ENSG00000132698	RAB25	97	67.633	ENSORLG00015012725	rab25a	69	67.633	Oryzias_latipes_hsok
ENSG00000132698	RAB25	96	69.268	ENSORLG00015019569	rab25b	98	68.367	Oryzias_latipes_hsok
ENSG00000132698	RAB25	98	67.943	ENSOMEG00000010510	rab25a	99	67.943	Oryzias_melastigma
ENSG00000132698	RAB25	97	68.599	ENSOMEG00000020350	rab25b	98	68.599	Oryzias_melastigma
ENSG00000132698	RAB25	100	97.183	ENSOGAG00000016955	RAB25	100	97.183	Otolemur_garnettii
ENSG00000132698	RAB25	100	94.366	ENSOARG00000005379	RAB25	100	94.366	Ovis_aries
ENSG00000132698	RAB25	100	100.000	ENSPPAG00000031127	RAB25	100	100.000	Pan_paniscus
ENSG00000132698	RAB25	100	98.122	ENSPPRG00000006611	RAB25	100	98.122	Panthera_pardus
ENSG00000132698	RAB25	100	100.000	ENSPTRG00000001446	RAB25	100	100.000	Pan_troglodytes
ENSG00000132698	RAB25	100	100.000	ENSPANG00000003113	RAB25	100	100.000	Papio_anubis
ENSG00000132698	RAB25	99	68.396	ENSPKIG00000020869	rab25a	99	68.396	Paramormyrops_kingsleyae
ENSG00000132698	RAB25	98	80.861	ENSPSIG00000013051	RAB25	98	80.861	Pelodiscus_sinensis
ENSG00000132698	RAB25	97	67.961	ENSPMGG00000001920	rab25a	97	67.961	Periophthalmus_magnuspinnatus
ENSG00000132698	RAB25	100	95.775	ENSPEMG00000007548	Rab25	100	95.775	Peromyscus_maniculatus_bairdii
ENSG00000132698	RAB25	100	91.549	ENSPCIG00000018951	RAB25	100	91.549	Phascolarctos_cinereus
ENSG00000132698	RAB25	93	65.327	ENSPFOG00000010632	rab25a	93	65.327	Poecilia_formosa
ENSG00000132698	RAB25	97	71.981	ENSPFOG00000011310	rab25b	98	71.981	Poecilia_formosa
ENSG00000132698	RAB25	97	71.981	ENSPLAG00000008004	rab25b	97	71.981	Poecilia_latipinna
ENSG00000132698	RAB25	98	66.507	ENSPLAG00000003558	rab25a	97	66.507	Poecilia_latipinna
ENSG00000132698	RAB25	97	66.667	ENSPMEG00000005491	rab25a	98	66.667	Poecilia_mexicana
ENSG00000132698	RAB25	97	71.981	ENSPMEG00000001400	rab25b	98	71.981	Poecilia_mexicana
ENSG00000132698	RAB25	98	66.986	ENSPREG00000006119	rab25a	88	76.923	Poecilia_reticulata
ENSG00000132698	RAB25	97	72.464	ENSPREG00000017337	rab25b	98	72.464	Poecilia_reticulata
ENSG00000132698	RAB25	100	99.531	ENSPPYG00000000730	RAB25	100	99.531	Pongo_abelii
ENSG00000132698	RAB25	100	97.653	ENSPCAG00000014579	RAB25	100	97.653	Procavia_capensis
ENSG00000132698	RAB25	100	97.653	ENSPCOG00000005144	RAB25	100	97.653	Propithecus_coquereli
ENSG00000132698	RAB25	93	89.394	ENSPVAG00000010331	RAB25	100	89.394	Pteropus_vampyrus
ENSG00000132698	RAB25	97	71.014	ENSPNYG00000018214	rab25b	98	71.014	Pundamilia_nyererei
ENSG00000132698	RAB25	98	66.986	ENSPNYG00000010491	rab25a	99	66.986	Pundamilia_nyererei
ENSG00000132698	RAB25	97	69.082	ENSPNAG00000006569	rab25b	98	69.082	Pygocentrus_nattereri
ENSG00000132698	RAB25	97	68.116	ENSPNAG00000000694	rab25a	99	68.116	Pygocentrus_nattereri
ENSG00000132698	RAB25	100	96.714	ENSRNOG00000023640	Rab25	100	96.714	Rattus_norvegicus
ENSG00000132698	RAB25	100	100.000	ENSRBIG00000044154	RAB25	100	100.000	Rhinopithecus_bieti
ENSG00000132698	RAB25	100	100.000	ENSRROG00000028851	RAB25	100	100.000	Rhinopithecus_roxellana
ENSG00000132698	RAB25	100	97.183	ENSSBOG00000032212	RAB25	100	97.183	Saimiri_boliviensis_boliviensis
ENSG00000132698	RAB25	100	93.458	ENSSHAG00000013327	RAB25	100	93.458	Sarcophilus_harrisii
ENSG00000132698	RAB25	99	70.476	ENSSFOG00015008657	rab25a	99	70.476	Scleropages_formosus
ENSG00000132698	RAB25	96	66.341	ENSSMAG00000016183	rab25b	95	66.341	Scophthalmus_maximus
ENSG00000132698	RAB25	98	65.550	ENSSMAG00000009722	rab25a	99	65.550	Scophthalmus_maximus
ENSG00000132698	RAB25	98	66.667	ENSSDUG00000009735	rab25a	98	66.667	Seriola_dumerili
ENSG00000132698	RAB25	92	67.857	ENSSDUG00000006260	rab25b	94	67.857	Seriola_dumerili
ENSG00000132698	RAB25	92	66.327	ENSSLDG00000009725	-	92	66.327	Seriola_lalandi_dorsalis
ENSG00000132698	RAB25	97	66.184	ENSSLDG00000010880	rab25a	98	66.184	Seriola_lalandi_dorsalis
ENSG00000132698	RAB25	97	69.565	ENSSLDG00000012091	rab25b	98	69.565	Seriola_lalandi_dorsalis
ENSG00000132698	RAB25	61	98.450	ENSSARG00000010854	RAB25	100	98.450	Sorex_araneus
ENSG00000132698	RAB25	98	74.194	ENSSPUG00000002555	RAB25	100	77.833	Sphenodon_punctatus
ENSG00000132698	RAB25	97	71.014	ENSSPAG00000012060	rab25b	98	71.014	Stegastes_partitus
ENSG00000132698	RAB25	98	68.421	ENSSPAG00000015817	rab25a	99	68.421	Stegastes_partitus
ENSG00000132698	RAB25	100	97.653	ENSSSCG00000039186	RAB25	100	97.653	Sus_scrofa
ENSG00000132698	RAB25	100	78.505	ENSTGUG00000003675	RAB25	100	78.505	Taeniopygia_guttata
ENSG00000132698	RAB25	98	67.464	ENSTRUG00000014595	-	99	67.464	Takifugu_rubripes
ENSG00000132698	RAB25	97	68.599	ENSTRUG00000007504	rab25b	98	68.599	Takifugu_rubripes
ENSG00000132698	RAB25	85	79.444	ENSTNIG00000004004	-	98	79.444	Tetraodon_nigroviridis
ENSG00000132698	RAB25	98	63.721	ENSTNIG00000005090	rab25a	98	63.721	Tetraodon_nigroviridis
ENSG00000132698	RAB25	91	96.907	ENSTBEG00000004142	RAB25	82	96.907	Tupaia_belangeri
ENSG00000132698	RAB25	100	84.507	ENSTTRG00000013345	RAB25	100	84.507	Tursiops_truncatus
ENSG00000132698	RAB25	97	94.175	ENSUAMG00000015697	RAB25	98	94.175	Ursus_americanus
ENSG00000132698	RAB25	100	96.714	ENSUMAG00000018376	RAB25	100	96.714	Ursus_maritimus
ENSG00000132698	RAB25	100	96.714	ENSVVUG00000005821	RAB25	100	96.714	Vulpes_vulpes
ENSG00000132698	RAB25	98	66.820	ENSXETG00000020404	rab25	98	66.820	Xenopus_tropicalis
ENSG00000132698	RAB25	98	65.116	ENSXCOG00000020125	rab25a	89	78.626	Xiphophorus_couchianus
ENSG00000132698	RAB25	91	74.227	ENSXCOG00000004227	rab25b	98	71.981	Xiphophorus_couchianus
ENSG00000132698	RAB25	98	66.507	ENSXMAG00000003233	rab25a	99	66.507	Xiphophorus_maculatus
ENSG00000132698	RAB25	91	74.227	ENSXMAG00000028745	rab25b	98	71.981	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003382	epithelial cell morphogenesis	-	ISS	Process
GO:0003924	GTPase activity	21873635.	IBA	Function
GO:0005515	protein binding	17925226.24955142.	IPI	Function
GO:0005525	GTP binding	-	IEA	Function
GO:0005768	endosome	21873635.	IBA	Component
GO:0006886	intracellular protein transport	21873635.	IBA	Process
GO:0006887	exocytosis	21873635.	IBA	Process
GO:0008284	positive regulation of cell proliferation	15502842.	IDA	Process
GO:0010634	positive regulation of epithelial cell migration	22613965.	IMP	Process
GO:0031143	pseudopodium	17925226.	IDA	Component
GO:0031260	pseudopodium membrane	-	IEA	Component
GO:0031268	pseudopodium organization	17925226.	IDA	Process
GO:0031410	cytoplasmic vesicle	17925226.22613965.	IDA	Component
GO:0031489	myosin V binding	24006491.	IPI	Function
GO:0032482	Rab protein signal transduction	21873635.	IBA	Process
GO:0055037	recycling endosome	21873635.	IBA	Component
GO:0060627	regulation of vesicle-mediated transport	22613965.	IMP	Process
GO:0070062	extracellular exosome	19056867.	HDA	Component

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.