EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
17178857	Multiple interacting oncogenes on the 8p11-p12 amplicon in human breast cancer.	Cancer Res	2006 Dec 15	Yang ZQ	-

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr19	18309751	Silent	rs764771715	A85A	0.26
BLCA	chr19	18323042	5'UTR	novel		0.3
BRCA	chr19	18312691	Silent	novel	L19L	0.05
BRCA	chr19	18312611	Missense_Mutation	novel	T46M	0.06	LSM
CESC	chr19	18307306	3'UTR	novel		0.28
CESC	chr19	18307251	3'UTR	novel		0.6
COAD	chr19	18309837	Missense_Mutation	NA	P57S	0.21
COAD	chr19	18307307	3'UTR	novel		0.63
COAD	chr19	18309834	Missense_Mutation	rs764476513	E58K	0.43
COAD	chr19	18312655	Silent	NA	S31S	0.42
HNSC	chr19	18309687	Missense_Mutation	novel	A107T	0.16
HNSC	chr19	18309863	Splice_Site	rs112426584	X49_splice	0.19
KIRP	chr19	18307398	3'UTR	novel		0.25
LIHC	chr19	18323083	5'UTR	novel		0.38
LUSC	chr19	18309847	Missense_Mutation	NA	F53L	0.23	LSM
LUSC	chr19	18309680	Missense_Mutation	novel	R109L	0.27
LUSC	chr19	18316061	Missense_Mutation	NA	P3L	0.39	LSM
LUSC	chr19	18312638	Missense_Mutation	NA	N37S	0.33	LSM
OV	chr19	18316060	Frame_Shift_Ins	novel	*L4Afs15**	0.2	LSM
PAAD	chr19	18309787	Silent	rs766768563	D73D	0.19
PAAD	chr19	18309834	Missense_Mutation	rs764476513	E58K	0.16
SKCM	chr19	18309694	Missense_Mutation	rs748477177	M104I	0.25
STAD	chr19	18309703	Silent	novel	G101G	0.1
STAD	chr19	18309742	Silent	rs765934857	R88R	0.39
STAD	chr19	18309778	Silent	rs138296949	I76I	0.17
UCEC	chr19	18309842	Missense_Mutation	rs781537682	R55Q	0.3	LSM
UCEC	chr19	18323061	5'UTR	novel		0.6
UCEC	chr19	18307373	3'UTR	novel		0.67
UCEC	chr19	18309687	Missense_Mutation	novel	A107T	0.52
UCEC	chr19	18309778	Silent	rs138296949	I76I	0.36
UCEC	chr19	18312652	Silent	NA	C32C	0.27
UCEC	chr19	18307286	3'UTR	novel		0.35
UCEC	chr19	18307479	Silent	novel	Q135Q	0.13
UCEC	chr19	18309798	Missense_Mutation	NA	R70C	0.38
UCEC	chr19	18309753	Missense_Mutation	novel	A85P	0.39
UCEC	chr19	18307418	3'UTR	rs535029436		0.41
UCEC	chr19	18307418	3'UTR	rs535029436		0.39
UCEC	chr19	18307292	3'UTR	novel		0.47
UCEC	chr19	18307368	3'UTR	novel		0.42
UCEC	chr19	18309789	Missense_Mutation	rs780420380	D73N	0.48
UCEC	chr19	18309681	Nonsense_Mutation	NA	R109*	0.31
UCEC	chr19	18312652	Silent	NA	C32C	0.3

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
READ	DEL	0.0788	0.23023
THCA	DEL	0.012	0.090402
THYM	DEL	0.0244	0.10691

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0005	Kaplan-Meier Survival Analysis
STAD	0.033	Kaplan-Meier Survival Analysis
ACC	0.00011	Kaplan-Meier Survival Analysis
SKCM	0.00039	Kaplan-Meier Survival Analysis
LAML	0.00014	Kaplan-Meier Survival Analysis
UCEC	0.034	Kaplan-Meier Survival Analysis
LIHC	0.0005	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
LUAD	0.02	Kaplan-Meier Survival Analysis
UVM	0.0019	Kaplan-Meier Survival Analysis
OV	0.002	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000130520 (Gene tree)
Gene ID: 25804
Gene Symbol: LSM4
Alias: YER112W
Full Name: LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 17,045 bases
Position: chr19:18,306,230-18,323,274
Accession: 17259
RBP type: canonical RBP
Summary: This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000469468	LSM	PF01423.22	3.2e-16	1	1
ENSP00000477443	LSM	PF01423.22	1e-15	1	1
ENSP00000475950	LSM	PF01423.22	3.3e-13	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
25449834	Proteomic analysis of oil bodies in mature Jatropha curcas seeds with different lipid content.	J Proteomics	2015 Jan 15	Liu H	doi: 10.1016/j.jprot.2014.10.013
22615807	Crystal structures of Lsm3, Lsm4 and Lsm5/6/7 from Schizosaccharomyces pombe.	PLoS One	2012	Wu D	doi: 10.1371/journal.pone.0036768
24810581	Validation of potential reference genes for qPCR in maize across abiotic stresses, hormone treatments, and tissue types.	PLoS One	2014 May 8	Lin Y	doi: 10.1371/journal.pone.0095445
24132150	A comparative proteomic analysis of Pinellia ternata leaves exposed to heat stress.	Int J Mol Sci	2013 Oct 15	Zhu Y	doi: 10.3390/ijms141020614.
10023572	The circadian system of Arabidopsis thaliana: forward and reverse genetic approaches.	Chronobiol Int	1999 Jan	Staiger D	-
2443491	Cloning of a full-length complementary DNA for an Artemia salina glycine-rich protein. Structural relationship with RNA binding proteins.	J Biol Chem	1987 Oct 5	Cruz-Alvarez M	-
1302645	RNA binding characteristics of a 16 kDa glycine-rich protein from maize.	Plant J	1992 Nov	Ludevid MD	-
9522463	The expression of an abscisic acid-responsive glycine-rich protein coincides with the level of seed dormancy in Fagus sylvatica.	Plant Cell Physiol	1997 Dec	Nicolas C	-
8054987	A light- and temperature-entrained circadian clock controls expression of transcripts encoding nuclear proteins with homology to RNA-binding proteins in meristematic tissue.	Plant J	1994 Jun	Heintzen C	-
11972043	A family of RRM-type RNA-binding proteins specific to plant mitochondria.	Proc Natl Acad Sci U S A	2002 Apr 30	Vermel M	-
20233706	[Cloning and stress tolerance analysis of an LbGRP gene in Limonium bicolor].	Yi Chuan	2010 Mar	Pan Y	-
26889112	Proteome Analysis of Disease Resistance against Ralstonia solanacearum in Potato Cultivar CT206-10.	Plant Pathol J	2016 Feb	Park S	doi: 10.5423/PPJ.OA.05.2015.0076
23555221	A circadian clock-regulated toggle switch explains AtGRP7 and AtGRP8 oscillations in Arabidopsis thaliana.	PLoS Comput Biol	2013	Schmal C	doi: 10.1371/journal.pcbi.1002986
26032221	Changes in the proteome of pad2-1, a glutathione depleted Arabidopsis mutant, during Pseudomonas syringae infection.	J Proteomics	2015 Aug 3	Datta R	doi: 10.1016/j.jprot.2015.04.036
29615482	Defining essential elements and genetic interactions of the yeast Lsm2-8 ring and demonstration that essentiality of Lsm2-8 is bypassed via overexpression of U6 snRNA or the U6 snRNP subunit Prp24.	RNA	2018 Jun	Roth AJ	doi: 10.1261/rna.066175.118
31242257	Genome-wide comparative analysis of RNA-binding Glycine-rich protein family genes between Gossypium arboreum and Gossypium raimondii.	PLoS One	2019 Jun 26	Yang W	doi: 10.1371/journal.pone.0218938

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000593564	LSM4-202	656	-	-	- (aa)	-	-
ENST00000594828	LSM4-204	807	-	ENSP00000477443	238 (aa)	-	V9GZ56
ENST00000600289	LSM4-206	1113	-	ENSP00000469028	69 (aa)	-	M0QXB0
ENST00000593829	LSM4-203	1908	-	ENSP00000469468	139 (aa)	-	Q9Y4Z0
ENST00000597776	LSM4-205	446	-	-	- (aa)	-	-
ENST00000252816	LSM4-201	986	-	ENSP00000475950	125 (aa)	-	U3KQK1

Gene Model

Click here to download ENSG00000130520's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03018	RNA degradation	KEGG
hsa03040	Spliceosome	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000130520	Emotions	7E-6	27089181

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000130520	rs148071254	19	18310252	G	Interleukin-2 receptor antagonist levels	27989323	[0.39-1.01] SD units increase	0.6978	EFO_0008332
ENSG00000130520	rs112595944	19	18314948	?	Red blood cell count	30595370			EFO_0004305

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000130520's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000130520	LSM4	52	34.722	ENSG00000100028	SNRPD3	59	34.722
ENSG00000130520	LSM4	70	32.000	ENSG00000204392	LSM2	82	35.000

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000130520	LSM4	99	75.000	ENSAPOG00000005643	lsm4	58	98.864	Acanthochromis_polyacanthus
ENSG00000130520	LSM4	100	100.000	ENSAMEG00000011162	LSM4	95	100.000	Ailuropoda_melanoleuca
ENSG00000130520	LSM4	99	77.622	ENSAOCG00000006414	lsm4	59	98.864	Amphiprion_ocellaris
ENSG00000130520	LSM4	99	75.000	ENSAPEG00000006238	lsm4	59	98.864	Amphiprion_percula
ENSG00000130520	LSM4	99	75.000	ENSATEG00000016559	lsm4	58	98.864	Anabas_testudineus
ENSG00000130520	LSM4	100	100.000	ENSANAG00000034659	LSM4	100	100.000	Aotus_nancymaae
ENSG00000130520	LSM4	99	75.000	ENSACLG00000022738	lsm4	60	98.864	Astatotilapia_calliptera
ENSG00000130520	LSM4	99	84.058	ENSAMXG00000016932	lsm4	62	97.727	Astyanax_mexicanus
ENSG00000130520	LSM4	100	100.000	ENSBTAG00000008578	LSM4	100	100.000	Bos_taurus
ENSG00000130520	LSM4	99	58.824	WBGene00003078	lsm-4	67	75.904	Caenorhabditis_elegans
ENSG00000130520	LSM4	100	100.000	ENSCJAG00000014171	LSM4	100	100.000	Callithrix_jacchus
ENSG00000130520	LSM4	99	100.000	ENSCAFG00000014900	LSM4	90	100.000	Canis_familiaris
ENSG00000130520	LSM4	100	100.000	ENSCAFG00020012137	LSM4	100	100.000	Canis_lupus_dingo
ENSG00000130520	LSM4	100	100.000	ENSCHIG00000010928	LSM4	91	100.000	Capra_hircus
ENSG00000130520	LSM4	100	99.281	ENSTSYG00000030906	LSM4	100	99.281	Carlito_syrichta
ENSG00000130520	LSM4	100	97.842	ENSCAPG00000014140	LSM4	100	97.842	Cavia_aperea
ENSG00000130520	LSM4	100	97.842	ENSCPOG00000024117	LSM4	100	97.842	Cavia_porcellus
ENSG00000130520	LSM4	100	100.000	ENSCCAG00000036308	LSM4	100	100.000	Cebus_capucinus
ENSG00000130520	LSM4	100	100.000	ENSCATG00000029311	LSM4	100	100.000	Cercocebus_atys
ENSG00000130520	LSM4	100	96.403	ENSCLAG00000010828	LSM4	100	96.403	Chinchilla_lanigera
ENSG00000130520	LSM4	100	100.000	ENSCSAG00000005370	LSM4	100	100.000	Chlorocebus_sabaeus
ENSG00000130520	LSM4	100	82.014	ENSCPBG00000012925	LSM4	100	89.928	Chrysemys_picta_bellii
ENSG00000130520	LSM4	99	73.529	ENSCING00000007519	-	69	92.045	Ciona_intestinalis
ENSG00000130520	LSM4	99	73.529	ENSCSAVG00000008596	-	70	93.182	Ciona_savignyi
ENSG00000130520	LSM4	100	100.000	ENSCANG00000043686	LSM4	100	100.000	Colobus_angolensis_palliatus
ENSG00000130520	LSM4	100	95.683	ENSCGRG00001014436	Lsm4	100	95.683	Cricetulus_griseus_chok1gshd
ENSG00000130520	LSM4	100	95.200	ENSCGRG00000009398	Lsm4	100	95.652	Cricetulus_griseus_crigri
ENSG00000130520	LSM4	99	75.000	ENSCSEG00000016127	lsm4	62	97.727	Cynoglossus_semilaevis
ENSG00000130520	LSM4	98	74.797	ENSCVAG00000021828	lsm4	56	97.260	Cyprinodon_variegatus
ENSG00000130520	LSM4	99	77.536	ENSCVAG00000010601	lsm4	62	97.727	Cyprinodon_variegatus
ENSG00000130520	LSM4	97	78.723	ENSDARG00000023852	lsm4	62	98.864	Danio_rerio
ENSG00000130520	LSM4	100	97.842	ENSDORG00000024225	Lsm4	100	97.842	Dipodomys_ordii
ENSG00000130520	LSM4	99	69.118	FBgn0032240	CG17768	57	88.636	Drosophila_melanogaster
ENSG00000130520	LSM4	99	98.387	ENSETEG00000007762	-	100	98.387	Echinops_telfairi
ENSG00000130520	LSM4	99	72.059	ENSEBUG00000003639	-	50	93.333	Eptatretus_burgeri
ENSG00000130520	LSM4	100	100.000	ENSECAG00000010141	LSM4	57	100.000	Equus_caballus
ENSG00000130520	LSM4	95	84.328	ENSELUG00000012821	lsm4	66	98.851	Esox_lucius
ENSG00000130520	LSM4	100	100.000	ENSFCAG00000040580	LSM4	100	100.000	Felis_catus
ENSG00000130520	LSM4	99	81.159	ENSFALG00000009478	LSM4	99	89.855	Ficedula_albicollis
ENSG00000130520	LSM4	100	96.800	ENSFDAG00000010124	LSM4	100	97.101	Fukomys_damarensis
ENSG00000130520	LSM4	81	91.379	ENSFHEG00000016353	lsm4	98	91.379	Fundulus_heteroclitus
ENSG00000130520	LSM4	97	74.627	ENSGMOG00000007729	lsm4	59	98.851	Gadus_morhua
ENSG00000130520	LSM4	100	81.295	ENSGALG00000003385	LSM4	100	89.928	Gallus_gallus
ENSG00000130520	LSM4	99	75.000	ENSGAFG00000004903	lsm4	55	94.521	Gambusia_affinis
ENSG00000130520	LSM4	99	75.000	ENSGACG00000008140	lsm4	59	98.864	Gasterosteus_aculeatus
ENSG00000130520	LSM4	100	82.014	ENSGAGG00000017812	LSM4	100	89.928	Gopherus_agassizii
ENSG00000130520	LSM4	100	100.000	ENSGGOG00000012914	-	100	100.000	Gorilla_gorilla
ENSG00000130520	LSM4	100	97.122	ENSHGLG00000006568	LSM4	100	97.122	Heterocephalus_glaber_female
ENSG00000130520	LSM4	99	75.000	ENSHGLG00100007894	LSM4	100	100.000	Heterocephalus_glaber_male
ENSG00000130520	LSM4	99	77.372	ENSHCOG00000008819	lsm4	62	98.864	Hippocampus_comes
ENSG00000130520	LSM4	99	84.058	ENSIPUG00000005368	Lsm4	62	98.864	Ictalurus_punctatus
ENSG00000130520	LSM4	100	100.000	ENSSTOG00000016494	LSM4	100	100.000	Ictidomys_tridecemlineatus
ENSG00000130520	LSM4	100	97.122	ENSJJAG00000017420	Lsm4	100	97.122	Jaculus_jaculus
ENSG00000130520	LSM4	99	75.000	ENSKMAG00000005073	lsm4	61	97.727	Kryptolebias_marmoratus
ENSG00000130520	LSM4	99	75.000	ENSLBEG00000027930	lsm4	73	94.545	Labrus_bergylta
ENSG00000130520	LSM4	99	83.212	ENSLACG00000015861	LSM4	98	83.212	Latimeria_chalumnae
ENSG00000130520	LSM4	93	83.721	ENSLOCG00000002025	lsm4	62	97.727	Lepisosteus_oculatus
ENSG00000130520	LSM4	100	98.400	ENSLAFG00000017459	LSM4	99	98.551	Loxodonta_africana
ENSG00000130520	LSM4	100	100.000	ENSMFAG00000031194	LSM4	100	100.000	Macaca_fascicularis
ENSG00000130520	LSM4	100	100.000	ENSMMUG00000004405	LSM4	100	100.000	Macaca_mulatta
ENSG00000130520	LSM4	100	100.000	ENSMNEG00000042899	LSM4	100	100.000	Macaca_nemestrina
ENSG00000130520	LSM4	100	100.000	ENSMLEG00000027948	LSM4	100	100.000	Mandrillus_leucophaeus
ENSG00000130520	LSM4	99	79.710	ENSMAMG00000006190	lsm4	77	94.545	Mastacembelus_armatus
ENSG00000130520	LSM4	99	75.000	ENSMZEG00005016420	lsm4	60	98.864	Maylandia_zebra
ENSG00000130520	LSM4	99	82.734	ENSMGAG00000004976	LSM4	99	89.855	Meleagris_gallopavo
ENSG00000130520	LSM4	100	99.281	ENSMICG00000000222	LSM4	100	99.281	Microcebus_murinus
ENSG00000130520	LSM4	100	96.403	ENSMOCG00000020861	Lsm4	100	96.403	Microtus_ochrogaster
ENSG00000130520	LSM4	99	95.968	ENSMODG00000015044	-	100	95.968	Monodelphis_domestica
ENSG00000130520	LSM4	99	77.143	ENSMALG00000018159	lsm4	62	97.727	Monopterus_albus
ENSG00000130520	LSM4	100	96.403	MGP_CAROLIEiJ_G0031158	Lsm4	100	96.403	Mus_caroli
ENSG00000130520	LSM4	100	96.403	ENSMUSG00000031848	Lsm4	100	96.403	Mus_musculus
ENSG00000130520	LSM4	100	96.403	MGP_PahariEiJ_G0021623	Lsm4	100	96.403	Mus_pahari
ENSG00000130520	LSM4	100	96.403	MGP_SPRETEiJ_G0032276	Lsm4	100	96.403	Mus_spretus
ENSG00000130520	LSM4	100	100.000	ENSMPUG00000015589	LSM4	100	100.000	Mustela_putorius_furo
ENSG00000130520	LSM4	100	100.000	ENSMLUG00000004010	LSM4	99	100.000	Myotis_lucifugus
ENSG00000130520	LSM4	100	96.403	ENSNGAG00000008644	Lsm4	100	96.403	Nannospalax_galili
ENSG00000130520	LSM4	97	74.627	ENSNBRG00000022150	lsm4	54	98.851	Neolamprologus_brichardi
ENSG00000130520	LSM4	99	92.742	ENSMEUG00000013229	LSM4	100	92.742	Notamacropus_eugenii
ENSG00000130520	LSM4	99	93.548	ENSOPRG00000005575	LSM4	100	83.065	Ochotona_princeps
ENSG00000130520	LSM4	100	73.381	ENSODEG00000011712	-	100	73.381	Octodon_degus
ENSG00000130520	LSM4	100	97.122	ENSODEG00000020549	-	100	97.122	Octodon_degus
ENSG00000130520	LSM4	100	87.050	ENSODEG00000004519	-	100	74.820	Octodon_degus
ENSG00000130520	LSM4	99	75.000	ENSONIG00000012724	lsm4	60	98.864	Oreochromis_niloticus
ENSG00000130520	LSM4	97	69.014	ENSOANG00000007434	LSM4	78	93.407	Ornithorhynchus_anatinus
ENSG00000130520	LSM4	99	85.106	ENSORLG00000008391	lsm4	61	97.727	Oryzias_latipes
ENSG00000130520	LSM4	99	75.000	ENSORLG00020014829	lsm4	61	97.727	Oryzias_latipes_hni
ENSG00000130520	LSM4	99	85.106	ENSORLG00015010205	lsm4	61	97.727	Oryzias_latipes_hsok
ENSG00000130520	LSM4	100	83.453	ENSOMEG00000003606	lsm4	61	97.727	Oryzias_melastigma
ENSG00000130520	LSM4	97	74.627	ENSOGAG00000027992	LSM4	60	100.000	Otolemur_garnettii
ENSG00000130520	LSM4	95	100.000	ENSOARG00000012553	LSM4	94	100.000	Ovis_aries
ENSG00000130520	LSM4	100	100.000	ENSPPAG00000044045	-	100	100.000	Pan_paniscus
ENSG00000130520	LSM4	100	100.000	ENSPPRG00000018264	LSM4	100	100.000	Panthera_pardus
ENSG00000130520	LSM4	100	100.000	ENSPTIG00000006306	LSM4	100	100.000	Panthera_tigris_altaica
ENSG00000130520	LSM4	100	100.000	ENSPTRG00000031470	LSM4	100	100.000	Pan_troglodytes
ENSG00000130520	LSM4	100	100.000	ENSPANG00000014399	LSM4	100	100.000	Papio_anubis
ENSG00000130520	LSM4	99	81.752	ENSPKIG00000006154	lsm4	62	98.864	Paramormyrops_kingsleyae
ENSG00000130520	LSM4	99	81.159	ENSPSIG00000012358	LSM4	100	89.855	Pelodiscus_sinensis
ENSG00000130520	LSM4	100	96.403	ENSPEMG00000001358	Lsm4	100	96.403	Peromyscus_maniculatus_bairdii
ENSG00000130520	LSM4	99	75.000	ENSPFOG00000000570	lsm4	63	81.513	Poecilia_formosa
ENSG00000130520	LSM4	99	76.389	ENSPLAG00000016267	lsm4	93	77.444	Poecilia_latipinna
ENSG00000130520	LSM4	98	78.417	ENSPMEG00000016378	lsm4	93	77.444	Poecilia_mexicana
ENSG00000130520	LSM4	100	100.000	ENSPPYG00000009736	LSM4	100	100.000	Pongo_abelii
ENSG00000130520	LSM4	99	98.387	ENSPCAG00000008513	LSM4	100	98.387	Procavia_capensis
ENSG00000130520	LSM4	100	99.281	ENSPCOG00000019837	LSM4	100	99.281	Propithecus_coquereli
ENSG00000130520	LSM4	100	100.000	ENSPVAG00000015383	LSM4	100	100.000	Pteropus_vampyrus
ENSG00000130520	LSM4	99	75.000	ENSPNYG00000016794	lsm4	60	98.864	Pundamilia_nyererei
ENSG00000130520	LSM4	96	83.582	ENSPNAG00000016598	lsm4	65	98.851	Pygocentrus_nattereri
ENSG00000130520	LSM4	100	96.403	ENSRNOG00000019572	Lsm4	100	96.403	Rattus_norvegicus
ENSG00000130520	LSM4	100	100.000	ENSRBIG00000024717	LSM4	100	100.000	Rhinopithecus_bieti
ENSG00000130520	LSM4	100	100.000	ENSRROG00000045706	LSM4	100	100.000	Rhinopithecus_roxellana
ENSG00000130520	LSM4	68	51.064	YER112W	LSM4	50	41.935	Saccharomyces_cerevisiae
ENSG00000130520	LSM4	100	100.000	ENSSBOG00000022455	LSM4	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000130520	LSM4	100	96.403	ENSSHAG00000011559	LSM4	100	96.403	Sarcophilus_harrisii
ENSG00000130520	LSM4	99	80.292	ENSSFOG00015021067	lsm4	99	75.540	Scleropages_formosus
ENSG00000130520	LSM4	99	75.000	ENSSMAG00000021020	lsm4	95	72.535	Scophthalmus_maximus
ENSG00000130520	LSM4	99	75.000	ENSSDUG00000009588	lsm4	53	98.864	Seriola_dumerili
ENSG00000130520	LSM4	99	75.000	ENSSLDG00000006827	lsm4	52	98.864	Seriola_lalandi_dorsalis
ENSG00000130520	LSM4	97	74.627	ENSSPUG00000010166	LSM4	56	98.851	Sphenodon_punctatus
ENSG00000130520	LSM4	99	75.000	ENSSPAG00000011615	lsm4	58	98.864	Stegastes_partitus
ENSG00000130520	LSM4	100	100.000	ENSSSCG00000034314	LSM4	100	100.000	Sus_scrofa
ENSG00000130520	LSM4	99	75.000	ENSTRUG00000021737	lsm4	62	96.591	Takifugu_rubripes
ENSG00000130520	LSM4	99	80.714	ENSTNIG00000010191	lsm4	61	97.727	Tetraodon_nigroviridis
ENSG00000130520	LSM4	100	100.000	ENSUAMG00000000665	LSM4	99	100.000	Ursus_americanus
ENSG00000130520	LSM4	100	100.000	ENSUMAG00000009013	LSM4	100	100.000	Ursus_maritimus
ENSG00000130520	LSM4	100	100.000	ENSVVUG00000008136	LSM4	71	100.000	Vulpes_vulpes
ENSG00000130520	LSM4	100	91.367	ENSXETG00000024933	lsm4	100	89.209	Xenopus_tropicalis
ENSG00000130520	LSM4	99	75.000	ENSXMAG00000026672	lsm4	63	80.672	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000387	spliceosomal snRNP assembly	21873635.	IBA	Process
GO:0000398	mRNA splicing, via spliceosome	28781166.	IDA	Process
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0000932	P-body	21873635.	IBA	Component
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0005515	protein binding	15231747.15905169.16189514.19628699.20584987.20696395.21988832.22365833.25416956.	IPI	Function
GO:0005634	nucleus	26912367.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005688	U6 snRNP	21873635.	IBA	Component
GO:0005829	cytosol	15905169.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0008380	RNA splicing	10523320.	TAS	Process
GO:0016020	membrane	15905169.	IDA	Component
GO:0017070	U6 snRNA binding	21873635.	IBA	Function
GO:0032991	protein-containing complex	15905169.	IDA	Component
GO:0033962	cytoplasmic mRNA processing body assembly	21873635.	IBA	Process
GO:0042731	PH domain binding	15905169.	IDA	Function
GO:0043005	neuron projection	-	IEA	Component
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	-	TAS	Process
GO:0046540	U4/U6 x U5 tri-snRNP complex	26912367.	IDA	Component
GO:0071005	U2-type precatalytic spliceosome	28781166.	IDA	Component
GO:0120115	Lsm2-8 complex	10523320.	IDA	Component

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

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Gene Model

Pathways

Phenotypes

GWAS

PPI

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Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.