EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
26196185	Endoplasmic reticulum ribosome-binding protein 1, RRBP1, promotes progression of colorectal cancer and predicts an unfavourable prognosis.	Br J Cancer	2015 Sep 1	Pan Y	doi: 10.1038/bjc.2015.260
19425502	[Colorectal cancer 2D-proteomics: identification of altered protein expression].	Mol Biol (Mosk)	2009 Mar-Apr	Krasnov GS	-
23318453	Endoplasmic reticulum ribosome-binding protein 1 (RRBP1) overexpression is frequently found in lung cancer patients and alleviates intracellular stress-induced apoptosis through the enhancement of GRP78.	Oncogene	2013 Oct 10	Tsai HY	doi: 10.1038/onc.2012.514

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr20	17659335	Intron	novel		0.12
ACC	chr20	17636667	Silent	novel	V316V	0.25
ACC	chr20	17641834	Missense_Mutation	rs146531264	A283V	0.09
BLCA	chr20	17643050	Missense_Mutation	rs144923230	E231K	0.13
BLCA	chr20	17620313	Missense_Mutation	novel	E756K	0.14
BLCA	chr20	17658941	Intron	novel		0.33
BLCA	chr20	17618628	Missense_Mutation	rs149077359	E810K	0.32
BLCA	chr20	17658646	Missense_Mutation	novel	Q191L	0.17
BLCA	chr20	17660331	Missense_Mutation	novel	K59N	0.52
BLCA	chr20	17660279	Missense_Mutation	novel	E77Q	0.2
BLCA	chr20	17620334	Missense_Mutation	NA	E749K	0.38
BLCA	chr20	17621923	Missense_Mutation	NA	L625V	0.22
BLCA	chr20	17619772	Intron	novel		0.27
BLCA	chr20	17658664	Missense_Mutation	rs770088879	S185I	0.34
BLCA	chr20	17615944	Silent	novel	L878L	0.07
BLCA	chr20	17636632	Missense_Mutation	rs773711997	R328H	0.24
BLCA	chr20	17621756	Silent	novel	L653L	0.41
BLCA	chr20	17621757	Missense_Mutation	novel	L653P	0.39
BLCA	chr20	17614860	Missense_Mutation	novel	K924N	0.22
BLCA	chr20	17641826	Missense_Mutation	rs144765063	A286T	0.14
BRCA	chr20	17660361	Missense_Mutation	NA	M49I	0.65
BRCA	chr20	17614836	Silent	rs752922096	R932R	0.09
BRCA	chr20	17614172	3'UTR	novel		0.38
BRCA	chr20	17660049	Silent	NA	V153V	0.14
BRCA	chr20	17624637	Missense_Mutation	novel	E596V	0.18
BRCA	chr20	17660005	Missense_Mutation	NA	A168D	0.57
BRCA	chr20	17660343	Nonsense_Mutation	novel	K56*	0.04
CESC	chr20	17659080	Intron	novel		0.22
CESC	chr20	17659445	Intron	novel		0.15
CESC	chr20	17659796	Intron	rs750909420		0.4
CESC	chr20	17641847	Missense_Mutation	NA	E279K	0.55
CESC	chr20	17659054	Intron	novel		0.18
CESC	chr20	17621457	Splice_Site	novel	X705_splice	0.3
CESC	chr20	17613960	3'UTR	rs115981891		0.33
CESC	chr20	17620298	Splice_Site	novel	X760_splice	0.35
CESC	chr20	17621765	Silent	rs148899277	T650T	0.38
CESC	chr20	17658852	Intron	rs577949870		0.13
CESC	chr20	17615938	Silent	rs146359410	A880A	0.13
CESC	chr20	17615931	Missense_Mutation	NA	E883Q	0.14
CESC	chr20	17659571	Intron	NA		0.21
CESC	chr20	17659849	Intron	rs189640892		0.28
CHOL	chr20	17659565	Intron	novel		0.1
COAD	chr20	17621913	Missense_Mutation	rs371943538	A628V	0.25
COAD	chr20	17627565	Missense_Mutation	NA	R523I	0.37
COAD	chr20	17627509	Missense_Mutation	rs755236092	V542I	0.27
COAD	chr20	17636678	Missense_Mutation	novel	K313Q	0.2
COAD	chr20	17660014	Missense_Mutation	rs142603533	S165L	0.53
COAD	chr20	17615486	Missense_Mutation	rs150160247	L899R	0.38
COAD	chr20	17621461	Silent	NA	E704E	0.44
COAD	chr20	17660443	Missense_Mutation	novel	A22D	0.05
COAD	chr20	17621477	Missense_Mutation	rs773607835	R699H	0.35
COAD	chr20	17659530	Intron	NA		0.19
COAD	chr20	17660358	Silent	NA	A50A	0.06
COAD	chr20	17620367	Missense_Mutation	NA	R738W	0.28
COAD	chr20	17659655	Intron	NA		0.37
COAD	chr20	17624614	Missense_Mutation	NA	A604T	0.27
COAD	chr20	17660238	Frame_Shift_Del	novel	*N91Mfs2**	0.04
COAD	chr20	17635554	Silent	NA	V383V	0.38
COAD	chr20	17621714	Silent	rs771337099	P667P	0.35
COAD	chr20	17621915	Frame_Shift_Ins	NA	*A628Gfs69**	0.35
COAD	chr20	17616738	Silent	rs769272121	P854P	0.26
COAD	chr20	17620778	Silent	rs750015969	S715S	0.43
COAD	chr20	17658957	Intron	novel		0.28
COAD	chr20	17659546	Intron	novel		0.15
COAD	chr20	17658669	Silent	novel	A183A	0.06
COAD	chr20	17659475	Intron	novel		0.45
COAD	chr20	17614832	Missense_Mutation	rs761671499	A934T	0.43
COAD	chr20	17659805	Intron	novel		0.05
COAD	chr20	17658891	Intron	NA		0.41
COAD	chr20	17659669	Intron	novel		0.15
COAD	chr20	17633484	Silent	rs752565485	F429F	0.29
COAD	chr20	17619704	Missense_Mutation	NA	E769K	0.3
COAD	chr20	17659624	Intron	NA		0.23
COAD	chr20	17614136	3'UTR	novel		0.16
COAD	chr20	17633561	Nonsense_Mutation	NA	E404*	0.27
COAD	chr20	17659414	Intron	NA		0.39
ESCA	chr20	17627564	Frame_Shift_Del	novel	*R523Sfs59**	0.24
ESCA	chr20	17658611	Nonsense_Mutation	novel	K203*	0.5
ESCA	chr20	17618611	Silent	rs371408403	S815S	0.14
ESCA	chr20	17659844	Intron	novel		0.08
ESCA	chr20	17660435	Missense_Mutation	novel	I25F	0.49
GBM	chr20	17627585	Missense_Mutation	novel	E516D	0.13
GBM	chr20	17660325	Silent	novel	K61K	0.2
GBM	chr20	17621879	Silent	novel	P639P	0.38
GBM	chr20	17627652	Missense_Mutation	rs747645888	A494V	0.35
GBM	chr20	17614760	Missense_Mutation	novel	L958M	0.13
HNSC	chr20	17633525	Missense_Mutation	novel	E416K	0.21
HNSC	chr20	17629893	Silent	novel	H460H	0.12
HNSC	chr20	17618662	Silent	novel	L798L	0.11
HNSC	chr20	17620347	Silent	rs114498635	L744L	0.11
HNSC	chr20	17629857	Silent	rs143484132	A472A	0.21
HNSC	chr20	17643044	Missense_Mutation	NA	E233K	0.15
HNSC	chr20	17620305	Silent	rs138279227	S758S	0.24
KIRC	chr20	17614056	3'UTR	novel		0.39
KIRC	chr20	17627543	Silent	novel	L530L	0.3
KIRC	chr20	17627544	Missense_Mutation	novel	L530Q	0.3
KIRC	chr20	17619632	Splice_Site	rs374039577	X792_splice	0.19
KIRC	chr20	17660473	Frame_Shift_Ins	novel	*V12Afs27**	0.06
KIRC	chr20	17660474	Missense_Mutation	novel	V12L	0.05
LAML	chr20	17636574	Splice_Region	novel		0.15
LGG	chr20	17627526	Missense_Mutation	rs550361889	A536V	0.51
LGG	chr20	17621939	Silent	rs772763744	S619S	0.07
LIHC	chr20	17615467	Silent	novel	L905L	0.47
LIHC	chr20	17615477	Missense_Mutation	NA	A902V	0.45
LIHC	chr20	17635553	Nonsense_Mutation	NA	E384*	0.31
LIHC	chr20	17658871	Intron	novel		0.48
LIHC	chr20	17659991	Missense_Mutation	novel	A173S	0.38
LUAD	chr20	17619714	Silent	rs772151393	T765T	0.28
LUAD	chr20	17627551	Missense_Mutation	NA	E528Q	0.15
LUAD	chr20	17636723	Missense_Mutation	novel	A298T	0.12
LUAD	chr20	17660238	Frame_Shift_Del	novel	*N91Mfs2**	0.45
LUAD	chr20	17621455	Splice_Region	novel		0.2
LUAD	chr20	17660219	Nonsense_Mutation	rs774473221	R97*	0.2
LUAD	chr20	17621762	Silent	NA	E651E	0.1
LUAD	chr20	17635585	Missense_Mutation	NA	R373L	0.15
LUAD	chr20	17641893	Silent	rs772859385	A263A	0.41
LUSC	chr20	17643095	Missense_Mutation	NA	P216S	0.61
LUSC	chr20	17660440	Missense_Mutation	rs756545346	I23S	0.4
LUSC	chr20	17618665	Silent	rs199571260	L797L	0.23
LUSC	chr20	17660088	Missense_Mutation	novel	K140N	0.26
LUSC	chr20	17660478	Silent	novel	G10G	0.14
LUSC	chr20	17627629	Missense_Mutation	novel	E502Q	0.11
LUSC	chr20	17614022	3'UTR	novel		0.26
LUSC	chr20	17614194	Silent	NA	G974G	0.25
LUSC	chr20	17658690	Splice_Site	novel	X177_splice	0.37
LUSC	chr20	17613985	3'UTR	novel		0.5
LUSC	chr20	17633517	Silent	novel	Q418Q	0.22
LUSC	chr20	17659007	Intron	novel		0.5
LUSC	chr20	17660495	Missense_Mutation	rs548871048	D5N	0.25
LUSC	chr20	17629856	Nonsense_Mutation	NA	E473*	0.5
LUSC	chr20	17615979	Missense_Mutation	novel	I867F	0.19
LUSC	chr20	17627632	Missense_Mutation	rs201534413	E501K	0.14
LUSC	chr20	17658842	Intron	novel		0.09
LUSC	chr20	17660193	Silent	novel	V105V	0.25
OV	chr20	17621545	Missense_Mutation	novel	D676E	0.4
OV	chr20	17658676	Missense_Mutation	novel	D181V	0.3
OV	chr20	17660345	Missense_Mutation	novel	Q55E	0.19
OV	chr20	17618598	Splice_Region	novel	L820L	0.1
OV	chr20	17660493	Silent	NA	D5D	0.11
OV	chr20	17621876	Silent	NA	E640E	0.26
OV	chr20	17659031	Intron	rs773330747		0.71
OV	chr20	17625523	Missense_Mutation	NA	V582L	0.11
PAAD	chr20	17629925	Missense_Mutation	rs147114989	R450C	0.2
PCPG	chr20	17633588	Missense_Mutation	novel	R395W	0.24
PCPG	chr20	17660292	Frame_Shift_Del	novel	*T72Kfs8**	0.14
PRAD	chr20	17614083	3'UTR	novel		0.12
PRAD	chr20	17641910	Nonsense_Mutation	NA	K258*	0.05
READ	chr20	17659671	Intron	NA		0.26
READ	chr20	17659839	Intron	novel		0.13
READ	chr20	17641802	Missense_Mutation	novel	N294D	0.07
READ	chr20	17614832	Missense_Mutation	rs761671499	A934T	0.37
READ	chr20	17614028	3'UTR	novel		0.34
READ	chr20	17658853	Intron	NA		0.12
SARC	chr20	17621718	Missense_Mutation	novel	H666R	0.34
SARC	chr20	17660163	Frame_Shift_Del	novel	*I116Lfs41**	0.57
SKCM	chr20	17659046	Intron	novel		0.36
SKCM	chr20	17621537	Missense_Mutation	novel	S679F	0.35
SKCM	chr20	17629904	Missense_Mutation	novel	E457K	0.17
SKCM	chr20	17641834	Missense_Mutation	novel	A283E	0.21
SKCM	chr20	17658956	Intron	novel		0.23
SKCM	chr20	17615970	Missense_Mutation	novel	D870N	0.46
SKCM	chr20	17633471	Silent	novel	L434L	0.09
SKCM	chr20	17633472	Silent	novel	V433V	0.08
SKCM	chr20	17620737	Missense_Mutation	NA	A729V	0.42
SKCM	chr20	17643095	Missense_Mutation	NA	P216S	0.41
SKCM	chr20	17627615	Silent	novel	L506L	0.5
SKCM	chr20	17629862	Missense_Mutation	novel	D471N	0.16
SKCM	chr20	17614177	3'UTR	rs775486059		0.19
SKCM	chr20	17615493	Missense_Mutation	NA	E897K	0.25
SKCM	chr20	17633516	Missense_Mutation	rs565385159	R419W	0.12
SKCM	chr20	17614873	Missense_Mutation	NA	L920Q	0.21
SKCM	chr20	17660157	Silent	rs368179898	I117I	0.27
SKCM	chr20	17660027	Nonsense_Mutation	NA	Q161*	0.45
SKCM	chr20	17658873	Intron	novel		0.3
SKCM	chr20	17616739	Missense_Mutation	novel	P854L	0.33
STAD	chr20	17621855	Missense_Mutation	NA	Q647H	0.06
STAD	chr20	17619598	Intron	novel		0.56
STAD	chr20	17616752	In_Frame_Del	novel	E846_P849del	0.07
STAD	chr20	17660359	Missense_Mutation	rs375344957	A50V	0.25
STAD	chr20	17618692	Intron	novel		0.31
STAD	chr20	17660230	Missense_Mutation	NA	T93S	0.3
STAD	chr20	17636607	Silent	rs374226751	H336H	0.3
STAD	chr20	17658801	Intron	novel		0.31
STAD	chr20	17641900	Frame_Shift_Ins	novel	*P261Rfs157**	0.23
STAD	chr20	17633612	Nonsense_Mutation	novel	Q387*	0.33
STAD	chr20	17625571	Silent	novel	L566L	0.11
STAD	chr20	17629959	Splice_Region	rs138539631	A438A	0.32
STAD	chr20	17627350	Splice_Region	rs773439510	T554T	0.12
STAD	chr20	17658890	Intron	NA		0.16
STAD	chr20	17620735	Missense_Mutation	rs759693376	A730T	0.09
STAD	chr20	17618743	Intron	NA		0.35
STAD	chr20	17660207	Missense_Mutation	rs745522355	R101W	0.37
STAD	chr20	17660162	Frame_Shift_Ins	novel	*I116Hfs128**	0.31
STAD	chr20	17660249	Missense_Mutation	NA	D87N	0.46
STAD	chr20	17633516	Missense_Mutation	rs565385159	R419W	0.24
STAD	chr20	17660496	Silent	rs200787681	Y4Y	0.08
STAD	chr20	17636646	Silent	rs531454797	T323T	0.19
STAD	chr20	17658734	Intron	rs759153442		0.13
STAD	chr20	17614804	Missense_Mutation	rs184544168	T943M	0.18
STAD	chr20	17620367	Missense_Mutation	NA	R738W	0.15
STAD	chr20	17636696	Missense_Mutation	rs547155729	G307R	0.36
THCA	chr20	17619746	Intron	novel		0.31
UCEC	chr20	17614836	Silent	rs752922096	R932R	0.3
UCEC	chr20	17621494	Silent	rs145465056	A693A	0.24
UCEC	chr20	17635660	Missense_Mutation	NA	R348Q	0.42
UCEC	chr20	17658612	Missense_Mutation	NA	K202N	0.32
UCEC	chr20	17627666	Silent	novel	L489L	0.32
UCEC	chr20	17658853	Intron	NA		0.07
UCEC	chr20	17660047	Missense_Mutation	novel	S154I	0.3
UCEC	chr20	17660291	Missense_Mutation	novel	K73E	0.42
UCEC	chr20	17625553	Missense_Mutation	rs761427770	E572K	0.45
UCEC	chr20	17658630	Missense_Mutation	novel	K196N	0.06
UCEC	chr20	17614794	Silent	novel	E946E	0.16
UCEC	chr20	17615493	Missense_Mutation	NA	E897K	0.39
UCEC	chr20	17619681	Missense_Mutation	rs777880554	M776I	0.46
UCEC	chr20	17658680	Missense_Mutation	novel	T180A	0.43
UCEC	chr20	17620347	Silent	rs114498635	L744L	0.45
UCEC	chr20	17614195	Missense_Mutation	NA	G974D	0.21
UCEC	chr20	17616786	Silent	novel	A838A	0.07
UCEC	chr20	17621693	Silent	NA	S674S	0.17
UCEC	chr20	17624603	Missense_Mutation	NA	E607D	0.21
UCEC	chr20	17636628	Missense_Mutation	NA	M329I	0.29
UCEC	chr20	17643128	Splice_Site	NA	X205_splice	0.31
UCEC	chr20	17620780	Missense_Mutation	novel	S715R	0.36
UCEC	chr20	17619714	Silent	rs772151393	T765T	0.31
UCEC	chr20	17641834	Missense_Mutation	rs146531264	A283V	0.31
UCEC	chr20	17659905	Intron	novel		0.13
UCEC	chr20	17618891	Intron	novel		0.22
UCEC	chr20	17633465	Silent	novel	L436L	0.15
UCEC	chr20	17636688	Silent	novel	A309A	0.25
UCEC	chr20	17643051	Silent	rs373094146	N230N	0.29
UCEC	chr20	17660028	Silent	rs778671797	I160I	0.2
UCEC	chr20	17641826	Missense_Mutation	rs144765063	A286T	0.4
UCEC	chr20	17620346	Missense_Mutation	rs201189565	E745K	0.37
UCEC	chr20	17614163	3'UTR	novel		0.33
UCEC	chr20	17658853	Intron	NA		0.45
UCEC	chr20	17660325	Missense_Mutation	NA	K61N	0.47
UCEC	chr20	17613874	3'UTR	novel		0.26
UCEC	chr20	17641818	Silent	novel	S288S	0.28
UCEC	chr20	17660279	Nonsense_Mutation	novel	E77*	0.2
UCEC	chr20	17659440	Intron	novel		0.39
UCEC	chr20	17621465	Missense_Mutation	rs368016675	A703V	0.35
UCEC	chr20	17659665	Intron	novel		0.38
UCEC	chr20	17643087	Missense_Mutation	novel	K218N	0.33
UCEC	chr20	17660207	Missense_Mutation	rs745522355	R101W	0.5
UCEC	chr20	17659505	Intron	novel		0.26
UCEC	chr20	17660462	Nonsense_Mutation	novel	G16*	0.44
UCEC	chr20	17635587	Silent	novel	L372L	0.2
UCEC	chr20	17643049	Missense_Mutation	novel	E231A	0.16
UCEC	chr20	17659582	Intron	novel		0.3
UCEC	chr20	17660494	Missense_Mutation	novel	D5V	0.27
UCEC	chr20	17627597	Silent	novel	E512E	0.38
UCEC	chr20	17633592	Silent	novel	K393K	0.24
UCEC	chr20	17624581	Missense_Mutation	novel	A615T	0.54
UCEC	chr20	17614095	3'UTR	novel		0.36
UCEC	chr20	17660157	Silent	rs368179898	I117I	0.37
UCEC	chr20	17614803	Silent	rs747482750	T943T	0.32
UCEC	chr20	17660277	Missense_Mutation	novel	E77D	0.4
UCEC	chr20	17636696	Missense_Mutation	novel	G307W	0.19
UCEC	chr20	17614142	3'UTR	novel		0.32
UCEC	chr20	17620346	Missense_Mutation	rs201189565	E745K	0.35
UCEC	chr20	17660088	Missense_Mutation	novel	K140N	0.17
UCEC	chr20	17620353	Silent	rs756142641	K742K	0.4
UCEC	chr20	17633534	Missense_Mutation	rs143879938	R413W	0.29
UCEC	chr20	17641883	Missense_Mutation	rs41276396	R267C	0.35
UCEC	chr20	17658783	Intron	rs199917212		0.27
UCEC	chr20	17659792	Intron	novel		0.39
UCEC	chr20	17619727	Missense_Mutation	novel	V761A	0.08
UCEC	chr20	17616759	Silent	rs371306215	A847A	0.36
UCEC	chr20	17619802	Intron	novel		0.5
UCEC	chr20	17629868	Missense_Mutation	rs112056169	R469W	0.23
UCEC	chr20	17641861	Missense_Mutation	NA	K274T	0.41
UCEC	chr20	17613923	3'UTR	novel		0.45
UCEC	chr20	17659914	Intron	novel		0.26
UCEC	chr20	17660325	Missense_Mutation	NA	K61N	0.28
UCEC	chr20	17660277	Missense_Mutation	novel	E77D	0.37
UCEC	chr20	17620346	Missense_Mutation	rs201189565	E745K	0.33
UCEC	chr20	17618688	Intron	novel		0.22
UCEC	chr20	17660143	Missense_Mutation	novel	A122V	0.4
UCEC	chr20	17659024	Intron	NA		0.54
UCEC	chr20	17614776	In_Frame_Del	novel	K952del	0.41
UCEC	chr20	17615964	Nonsense_Mutation	novel	Q872*	0.22
UCEC	chr20	17614095	3'UTR	novel		0.28
UCEC	chr20	17659812	Intron	novel		0.36
UCEC	chr20	17613831	3'UTR	novel		0.35
UCEC	chr20	17658740	Intron	novel		0.1
UCS	chr20	17660347	Missense_Mutation	novel	H54R	0.12
UVM	chr20	17658650	Missense_Mutation	rs758259417	K190E	0.39

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1333	0.030954
LUAD	DEL	0.1802	0.15188

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00023	Kaplan-Meier Survival Analysis
STAD	0.016	Kaplan-Meier Survival Analysis
SARC	0.0029	Kaplan-Meier Survival Analysis
MESO	0.0014	Kaplan-Meier Survival Analysis
LUSC	0.03	Kaplan-Meier Survival Analysis
ESCA	0.023	Kaplan-Meier Survival Analysis
BLCA	0.00033	Kaplan-Meier Survival Analysis
CESC	0.0023	Kaplan-Meier Survival Analysis
LAML	0.044	Kaplan-Meier Survival Analysis
UCEC	0.00011	Kaplan-Meier Survival Analysis
GBM	0.049	Kaplan-Meier Survival Analysis
LIHC	0.049	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
CHOL	0.039	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Pathway

GWAS

PPI

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000125844 (Gene tree)
Gene ID: 6238
Gene Symbol: RRBP1
Alias: ES/130|hES
Full Name: ribosome binding protein 1
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Minus strand
Length: 68,618 bases
Position: chr20:17,613,678-17,682,295
Accession: 10448
Summary: This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12. [provided by RefSeq, Apr 2012]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000468428	RRBP1-207	2200	-	-	- (aa)	-	-
ENST00000470422	RRBP1-208	2070	-	ENSP00000478324	346 (aa)	-	A0A087WU26
ENST00000495501	RRBP1-209	832	-	ENSP00000476483	229 (aa)	-	V9GY78
ENST00000377807	RRBP1-203	3792	-	ENSP00000367038	977 (aa)	-	Q9P2E9
ENST00000377813	RRBP1-204	5041	-	ENSP00000367044	1410 (aa)	-	Q9P2E9
ENST00000398782	RRBP1-205	1191	-	ENSP00000381762	300 (aa)	-	A2A2S5
ENST00000610403	RRBP1-210	3309	-	ENSP00000479709	934 (aa)	-	A0A087WVV2
ENST00000360807	RRBP1-202	3727	-	ENSP00000354045	977 (aa)	-	Q9P2E9
ENST00000620641	RRBP1-211	582	-	-	- (aa)	-	-
ENST00000246043	RRBP1-201	4737	-	ENSP00000246043	1410 (aa)	-	Q9P2E9
ENST00000455029	RRBP1-206	2485	-	ENSP00000401206	751 (aa)	-	F8W7S5

Gene Model

Click here to download ENSG00000125844's gene model file

Pathway

Pathway ID	Pathway Name	Source
hsa04141	Protein processing in endoplasmic reticulum	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000125844	rs13734	20	17614084	A	Coronary artery disease	29212778	[0.023-0.054] unit increase	0.0384	EFO_0000378
ENSG00000125844	rs6080761	20	17648517	?	Eosinophil counts	30595370			EFO_0004842

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000125844's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000125844	RRBP1	100	86.818	ENSMUSG00000027422	Rrbp1	100	79.348	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001649	osteoblast differentiation	16210410.	HDA	Process
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0005783	endoplasmic reticulum	-	IDA	Component
GO:0005840	ribosome	9628588.	TAS	Component
GO:0006412	translation	9628588.	TAS	Process
GO:0015031	protein transport	-	IEA	Process
GO:0016020	membrane	16210410.	HDA	Component
GO:0030176	integral component of endoplasmic reticulum membrane	21873635.	IBA	Component
GO:0038023	signaling receptor activity	9628588.	TAS	Function

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Pathway

GWAS

PPI

Ortholog

Gene Ontology

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Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

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