EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr20	57611776	Silent	rs370372910	H275H	0.19
BLCA	chr20	57611790	Missense_Mutation	NA	E271Q	0.17
BLCA	chr20	57614969	Silent	novel	V140V	0.06
BLCA	chr20	57616398	Silent	novel	V35V	0.24
BLCA	chr20	57613260	Missense_Mutation	novel	Q191H	0.28
BLCA	chr20	57604580	Missense_Mutation	novel	G428A	0.06
BLCA	chr20	57604728	Frame_Shift_Del	novel	*D370Rfs38**	0.14
BLCA	chr20	57604635	Missense_Mutation	novel	E410Q	0.36
BRCA	chr20	57604702	Silent	novel	P387P	0.09
BRCA	chr20	57604447	3'UTR	novel		0.26
BRCA	chr20	57604742	Missense_Mutation	NA	R374I	0.3
BRCA	chr20	57613318	Missense_Mutation	novel	R172K	0.09
CESC	chr20	57616416	Silent	NA	V29V	0.46
CESC	chr20	57604273	3'UTR	rs576620878		0.43
CESC	chr20	57611903	Missense_Mutation	novel	S233L	0.39
COAD	chr20	57611874	Missense_Mutation	NA	G243R	0.13
COAD	chr20	57614965	Nonsense_Mutation	rs754746401	R142*	0.33
COAD	chr20	57610337	Missense_Mutation	rs147660947	S302L	0.14
COAD	chr20	57615034	Missense_Mutation	novel	D119Y	0.23
COAD	chr20	57613331	Splice_Site	novel	X168_splice	0.26
COAD	chr20	57615016	Missense_Mutation	novel	A125T	0.26
COAD	chr20	57610288	Silent	rs146958594	A318A	0.13
COAD	chr20	57614997	Missense_Mutation	novel	A131V	0.33
COAD	chr20	57613068	Intron	novel		0.39
COAD	chr20	57610336	Silent	rs374383138	S302S	0.33
COAD	chr20	57604587	Nonsense_Mutation	NA	G426*	0.58
COAD	chr20	57611857	Silent	NA	P248P	0.11
COAD	chr20	57604755	Missense_Mutation	NA	D370N	0.34
COAD	chr20	57611813	Missense_Mutation	NA	R263L	0.1
COAD	chr20	57604504	3'UTR	novel		0.32
COAD	chr20	57614977	Missense_Mutation	novel	K138E	0.18
COAD	chr20	57613069	Intron	novel		0.33
DLBC	chr20	57620267	Missense_Mutation	novel	R10K	0.4
ESCA	chr20	57613049	Intron	novel		0.13
ESCA	chr20	57604761	Missense_Mutation	rs762891234	P368S	0.49
GBM	chr20	57613253	Missense_Mutation	novel	P194A	0.06
GBM	chr20	57613243	Nonsense_Mutation	novel	W197*	0.19
GBM	chr20	57604484	3'UTR	novel		0.19
GBM	chr20	57604767	Missense_Mutation	rs141295310	R366C	0.36
GBM	chr20	57613320	Silent	novel	G171G	0.12
GBM	chr20	57616346	Missense_Mutation	NA	K53Q	0.35	z-alpha
GBM	chr20	57615533	Missense_Mutation	NA	P103S	0.3
HNSC	chr20	57613331	Splice_Site	novel	X168_splice	0.41
HNSC	chr20	57614909	Silent	novel	K160K	0.31
HNSC	chr20	57616277	Missense_Mutation	novel	E76K	0.29
HNSC	chr20	57614890	Missense_Mutation	novel	P167S	0.33
HNSC	chr20	57614984	Missense_Mutation	novel	R135S	0.42
KICH	chr20	57610249	Silent	rs186925447	D331D	0.46
KIRC	chr20	57610199	Missense_Mutation	rs752942618	G348D	0.37
KIRC	chr20	57620324	5'UTR	novel		0.44
KIRP	chr20	57620273	Missense_Mutation	rs762116149	P8L	0.03
LIHC	chr20	57604573	Silent	NA	*430*	0.24
LIHC	chr20	57613261	Missense_Mutation	novel	Q191L	0.21
LUAD	chr20	57616290	Silent	NA	T71T	0.11
LUAD	chr20	57613176	Silent	NA	V219V	0.87
LUAD	chr20	57604619	Missense_Mutation	rs764079652	V415A	0.35
LUAD	chr20	57611779	Silent	novel	L274L	0.11
LUAD	chr20	57611752	Silent	NA	A283A	0.54
LUAD	chr20	57613212	Missense_Mutation	novel	Q207H	0.05
LUAD	chr20	57616261	Missense_Mutation	novel	L81Q	0.31
LUAD	chr20	57610255	Silent	novel	L329L	0.12
LUAD	chr20	57604598	Missense_Mutation	novel	G422E	0.09
LUAD	chr20	57604426	3'UTR	novel		0.14
LUAD	chr20	57611769	Missense_Mutation	novel	P278S	0.87
LUSC	chr20	57604519	3'UTR	novel		0.19
LUSC	chr20	57616433	Missense_Mutation	novel	E24Q	0.07	z-alpha
LUSC	chr20	57604677	Missense_Mutation	novel	L396M	0.35
LUSC	chr20	57604605	Missense_Mutation	novel	H420Y	0.33
LUSC	chr20	57613179	Silent	novel	T218T	0.24
LUSC	chr20	57611837	Missense_Mutation	novel	H255L	0.19
LUSC	chr20	57610280	Missense_Mutation	NA	R321K	0.57
LUSC	chr20	57611839	Silent	NA	I254I	0.24
LUSC	chr20	57615530	Missense_Mutation	NA	Q104E	0.19
LUSC	chr20	57610175	Missense_Mutation	rs77921447	G356V	0.3
LUSC	chr20	57615544	Missense_Mutation	novel	E99G	0.38
LUSC	chr20	57613143	Intron	novel		0.37
LUSC	chr20	57604434	3'UTR	novel		0.6
LUSC	chr20	57604598	Missense_Mutation	novel	G422A	0.3
LUSC	chr20	57614984	Silent	novel	R135R	0.28
OV	chr20	57610327	Silent	novel	A305A	0.32
OV	chr20	57616290	Silent	NA	T71T	0.1
OV	chr20	57613210	Missense_Mutation	NA	I208T	0.37
OV	chr20	57613212	Missense_Mutation	novel	Q207H	0.04
OV	chr20	57610309	Silent	novel	G311G	0.07
OV	chr20	57604627	Silent	NA	S412S	0.21
OV	chr20	57615004	Missense_Mutation	rs141977359	A129T	0.35
OV	chr20	57614945	Missense_Mutation	NA	K148N	0.35
OV	chr20	57604318	3'UTR	novel		0.08
PAAD	chr20	57611793	Missense_Mutation	novel	N270H	0.14
PRAD	chr20	57610336	Silent	rs374383138	S302S	0.06
READ	chr20	57610264	Silent	rs143130163	S326S	0.06
READ	chr20	57604767	Missense_Mutation	rs141295310	R366C	0.16
READ	chr20	57615018	Missense_Mutation	NA	R124M	0.1
READ	chr20	57610307	Missense_Mutation	NA	T312N	0.16
SARC	chr20	57616373	Missense_Mutation	rs772926217	E44K	0.16	z-alpha
SARC	chr20	57611768	Missense_Mutation	novel	P278Q	0.07
SKCM	chr20	57610168	Silent	novel	G358G	0.34
SKCM	chr20	57614964	Missense_Mutation	rs751395998	R142Q	0.44
SKCM	chr20	57604602	Missense_Mutation	NA	E421K	0.32
SKCM	chr20	57611731	Silent	NA	P290P	0.59
SKCM	chr20	57610301	Missense_Mutation	novel	P314L	0.56
SKCM	chr20	57615558	Silent	NA	A94A	0.27
SKCM	chr20	57610170	Missense_Mutation	NA	G358R	0.24
SKCM	chr20	57610171	Silent	rs745740982	E357E	0.24
SKCM	chr20	57615001	Nonsense_Mutation	novel	Q130*	0.16
SKCM	chr20	57615002	Silent	novel	A129A	0.16
SKCM	chr20	57620358	5'UTR	novel		0.4
SKCM	chr20	57615513	Splice_Region	novel	R109R	0.34
SKCM	chr20	57616368	Silent	NA	L45L	0.26
SKCM	chr20	57616407	Silent	NA	A32A	0.14
SKCM	chr20	57604764	Missense_Mutation	rs751287186	R367C	0.1
SKCM	chr20	57604687	Silent	NA	L392L	0.06
SKCM	chr20	57616426	Missense_Mutation	NA	G26D	0.13	z-alpha
SKCM	chr20	57616311	Silent	novel	A64A	0.48
SKCM	chr20	57604520	3'UTR	novel		0.48
SKCM	chr20	57613126	Intron	novel		0.52
SKCM	chr20	57615005	Silent	rs774963938	I128I	0.48
SKCM	chr20	57616318	Missense_Mutation	rs368022689	S62F	0.33
SKCM	chr20	57616344	Missense_Mutation	novel	K53N	0.45	z-alpha
SKCM	chr20	57614900	Silent	NA	T163T	0.72
SKCM	chr20	57604727	Missense_Mutation	rs748618471	R379Q	0.34
SKCM	chr20	57615058	Missense_Mutation	rs764212417	E111K	0.29
SKCM	chr20	57613122	Intron	novel		0.23
SKCM	chr20	57616363	Missense_Mutation	NA	Q47R	0.41	z-alpha
SKCM	chr20	57616394	Missense_Mutation	novel	E37K	0.33	z-alpha
STAD	chr20	57613114	Intron	novel		0.11
STAD	chr20	57604758	Missense_Mutation	rs765287829	A369T	0.32
STAD	chr20	57615515	Missense_Mutation	rs746334067	R109W	0.11
STAD	chr20	57614964	Missense_Mutation	rs751395998	R142Q	0.37
STAD	chr20	57614932	Frame_Shift_Ins	novel	*L153Sfs5**	0.21
STAD	chr20	57613182	Silent	novel	Q217Q	0.24
STAD	chr20	57604483	3'UTR	novel		0.17
STAD	chr20	57614965	Nonsense_Mutation	rs754746401	R142*	0.26
STAD	chr20	57604529	3'UTR	novel		0.24
UCEC	chr20	57620351	5'UTR	novel		0.38
UCEC	chr20	57613203	Silent	rs368487372	H210H	0.35
UCEC	chr20	57616280	Missense_Mutation	NA	G75C	0.49
UCEC	chr20	57611754	Missense_Mutation	novel	A283T	0.52
UCEC	chr20	57616296	Silent	rs765740931	G69G	0.4
UCEC	chr20	57620469	5'UTR	novel		0.24
UCEC	chr20	57615061	Splice_Site	NA	X110_splice	0.16
UCEC	chr20	57613113	Intron	rs184861014		0.46
UCEC	chr20	57615535	Missense_Mutation	novel	G102D	0.47
UCEC	chr20	57613203	Silent	rs368487372	H210H	0.38
UCEC	chr20	57616329	Silent	novel	V58V	0.06
UCEC	chr20	57620269	Silent	NA	G9G	0.19
UCEC	chr20	57604654	Silent	novel	N403N	0.15
UCEC	chr20	57613269	Missense_Mutation	NA	M188I	0.41
UCEC	chr20	57616452	Missense_Mutation	novel	R17S	0.47	z-alpha
UCEC	chr20	57620444	5'UTR	novel		0.31
UCEC	chr20	57604504	3'UTR	novel		0.56
UCEC	chr20	57611829	Nonsense_Mutation	NA	Q258*	0.14
UCEC	chr20	57610265	Nonsense_Mutation	rs148258013	S326*	0.39
UCEC	chr20	57613143	Intron	novel		0.25
UCEC	chr20	57616312	Missense_Mutation	novel	A64V	0.2
UCEC	chr20	57620386	5'UTR	novel		0.29
UCEC	chr20	57604766	Missense_Mutation	rs754610408	R366H	0.31
UCEC	chr20	57604471	3'UTR	novel		0.37
UCEC	chr20	57613242	Nonsense_Mutation	NA	W197*	0.3
UCEC	chr20	57604387	3'UTR	novel		0.39
UCEC	chr20	57610280	Missense_Mutation	novel	R321I	0.54
UCEC	chr20	57613273	Missense_Mutation	novel	N187S	0.5
UCEC	chr20	57616383	Silent	novel	A40A	0.4
UCEC	chr20	57610325	Missense_Mutation	novel	R306I	0.2
UCEC	chr20	57615534	Silent	novel	G102G	0.42
UCEC	chr20	57604525	3'UTR	novel		0.46
UCEC	chr20	57610244	Missense_Mutation	novel	T333I	0.41
UCEC	chr20	57604396	3'UTR	novel		0.42
UCEC	chr20	57604758	Missense_Mutation	rs765287829	A369T	0.29
UCEC	chr20	57604560	3'UTR	rs376791022		0.32
UCEC	chr20	57620322	5'UTR	novel		0.21
UCEC	chr20	57611840	Missense_Mutation	novel	I254T	0.43
UCEC	chr20	57620362	5'UTR	novel		0.21
UCEC	chr20	57614976	Missense_Mutation	novel	K138T	0.5
UCEC	chr20	57604432	3'UTR	novel		0.17
UCEC	chr20	57610265	Missense_Mutation	rs148258013	S326L	0.36
UCEC	chr20	57613133	Intron	novel		0.31
UCEC	chr20	57620319	5'UTR	rs372043119		0.33
UCEC	chr20	57610280	Missense_Mutation	novel	R321I	0.45

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
PRAD	AMP	0.0549	0.07085
SARC	AMP	0.323	0.033553
SKCM	AMP	0.4496	0.058021

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0019	Kaplan-Meier Survival Analysis
KIRC	0.0001	Kaplan-Meier Survival Analysis
SARC	0.011	Kaplan-Meier Survival Analysis
MESO	0.0035	Kaplan-Meier Survival Analysis
HNSC	0.00057	Kaplan-Meier Survival Analysis
LUSC	0.042	Kaplan-Meier Survival Analysis
BRCA	0.033	Kaplan-Meier Survival Analysis
LAML	0.0089	Kaplan-Meier Survival Analysis
LIHC	0.031	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
LUAD	0.031	Kaplan-Meier Survival Analysis
UVM	0.00083	Kaplan-Meier Survival Analysis
OV	0.0033	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000124256 (Gene tree)
Gene ID: 81030
Gene Symbol: ZBP1
Alias: dJ718J7.3|DLM1|DLM-1|DAI|C20orf183
Full Name: Z-DNA binding protein 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 16,731 bases
Position: chr20:57,603,846-57,620,576
Accession: 16176
RBP type: canonical RBP
Summary: This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000440552	z-alpha	PF02295.17	1.3e-13	1	2
ENSP00000440552	z-alpha	PF02295.17	1.3e-13	2	2
ENSP00000360215	z-alpha	PF02295.17	7.2e-13	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
28716805	Sensing of viral and endogenous RNA by ZBP1/DAI induces necroptosis.	EMBO J	2017 Sep 1	Maelfait J	doi: 10.15252/embj.201796476
20456414	Nucleic acid sensing receptors in systemic lupus erythematosus: development of novel DNA- and/or RNA-like analogues for treating lupus.	Clin Exp Immunol	2010 Aug	Lenert P	doi: 10.1111/j.1365-2249.2010.04176.x
11842111	Complex regulation of the human gene for the Z-DNA binding protein DLM-1.	Nucleic Acids Res	2002 Feb 15	Rothenburg S	-
16990255	ZBP1 subcellular localization and association with stress granules is controlled by its Z-DNA binding domains.	Nucleic Acids Res	2006	Deigendesch N	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000395822	ZBP1-202	2073	-	ENSP00000379167	354 (aa)	-	Q9H171
ENST00000461547	ZBP1-205	4213	-	-	- (aa)	-	-
ENST00000480037	ZBP1-206	1737	-	-	- (aa)	-	-
ENST00000538947	ZBP1-207	589	-	-	- (aa)	-	-
ENST00000546110	ZBP1-209	558	-	-	- (aa)	-	-
ENST00000432548	ZBP1-203	573	-	-	- (aa)	-	-
ENST00000453793	ZBP1-204	357	-	ENSP00000404620	119 (aa)	-	H0Y6D1
ENST00000371173	ZBP1-201	2195	XM_011529057	ENSP00000360215	429 (aa)	XP_011527359	Q9H171
ENST00000541799	ZBP1-208	1041	XM_017028086	ENSP00000440552	248 (aa)	XP_016883575	Q9H171

Gene Model

Click here to download ENSG00000124256's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04217	Necroptosis	KEGG
hsa04623	Cytosolic DNA-sensing pathway	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000124256	Body Fat Distribution	6.1800000E-005	-
ENSG00000124256	Body Fat Distribution	3.4780000E-005	-
ENSG00000124256	Coronary Disease	8.0190000E-005	-
ENSG00000124256	Hippocampus	2E-6	19668339

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000124256	rs2073145	20	57615578	?	Hippocampal atrophy	19668339			EFO_0005039

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000124256's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000124256	ZBP1	90	62.054	ENSAMEG00000012704	-	100	57.552	Ailuropoda_melanoleuca
ENSG00000124256	ZBP1	99	81.882	ENSANAG00000038003	ZBP1	100	82.258	Aotus_nancymaae
ENSG00000124256	ZBP1	100	80.653	ENSCJAG00000019094	ZBP1	100	80.653	Callithrix_jacchus
ENSG00000124256	ZBP1	92	56.710	ENSCAFG00000023783	ZBP1	98	50.233	Canis_familiaris
ENSG00000124256	ZBP1	98	52.225	ENSCAFG00020022005	ZBP1	95	52.225	Canis_lupus_dingo
ENSG00000124256	ZBP1	91	56.388	ENSCHIG00000006747	-	86	54.617	Capra_hircus
ENSG00000124256	ZBP1	94	54.831	ENSCPOG00000008569	ZBP1	98	54.831	Cavia_porcellus
ENSG00000124256	ZBP1	100	79.720	ENSCCAG00000009469	ZBP1	99	79.720	Cebus_capucinus
ENSG00000124256	ZBP1	98	89.048	ENSCATG00000013143	ZBP1	100	89.048	Cercocebus_atys
ENSG00000124256	ZBP1	95	56.057	ENSCLAG00000012154	ZBP1	99	55.582	Chinchilla_lanigera
ENSG00000124256	ZBP1	92	34.874	ENSCPBG00000023941	ZBP1	82	30.376	Chrysemys_picta_bellii
ENSG00000124256	ZBP1	100	89.548	ENSCANG00000035951	ZBP1	100	89.548	Colobus_angolensis_palliatus
ENSG00000124256	ZBP1	96	48.821	ENSCGRG00001015544	Zbp1	96	48.585	Cricetulus_griseus_chok1gshd
ENSG00000124256	ZBP1	96	48.471	ENSCGRG00000002294	Zbp1	95	48.235	Cricetulus_griseus_crigri
ENSG00000124256	ZBP1	93	56.436	ENSDNOG00000002438	-	90	54.455	Dasypus_novemcinctus
ENSG00000124256	ZBP1	94	54.390	ENSEASG00005023257	ZBP1	96	54.390	Equus_asinus_asinus
ENSG00000124256	ZBP1	94	54.146	ENSECAG00000017185	ZBP1	96	54.146	Equus_caballus
ENSG00000124256	ZBP1	91	48.230	ENSEEUG00000002058	-	99	46.647	Erinaceus_europaeus
ENSG00000124256	ZBP1	88	62.844	ENSFCAG00000000420	-	95	62.844	Felis_catus
ENSG00000124256	ZBP1	100	97.902	ENSGGOG00000011001	ZBP1	100	97.902	Gorilla_gorilla
ENSG00000124256	ZBP1	98	88.810	ENSMFAG00000030920	ZBP1	100	88.810	Macaca_fascicularis
ENSG00000124256	ZBP1	98	88.571	ENSMMUG00000022588	ZBP1	100	88.571	Macaca_mulatta
ENSG00000124256	ZBP1	98	88.571	ENSMNEG00000043957	ZBP1	100	88.571	Macaca_nemestrina
ENSG00000124256	ZBP1	100	84.382	ENSMLEG00000031509	ZBP1	100	84.382	Mandrillus_leucophaeus
ENSG00000124256	ZBP1	95	50.204	ENSMAUG00000001095	Zbp1	99	41.084	Mesocricetus_auratus
ENSG00000124256	ZBP1	94	59.829	ENSMICG00000046613	ZBP1	100	50.339	Microcebus_murinus
ENSG00000124256	ZBP1	98	48.284	ENSMOCG00000019061	Zbp1	98	48.284	Microtus_ochrogaster
ENSG00000124256	ZBP1	96	46.667	MGP_CAROLIEiJ_G0024748	Zbp1	96	46.667	Mus_caroli
ENSG00000124256	ZBP1	96	47.017	ENSMUSG00000027514	Zbp1	95	47.017	Mus_musculus
ENSG00000124256	ZBP1	90	50.649	MGP_PahariEiJ_G0026189	-	85	47.712	Mus_pahari
ENSG00000124256	ZBP1	96	46.778	MGP_SPRETEiJ_G0025668	Zbp1	95	46.778	Mus_spretus
ENSG00000124256	ZBP1	97	53.302	ENSMPUG00000006670	-	94	53.302	Mustela_putorius_furo
ENSG00000124256	ZBP1	90	50.222	ENSMLUG00000017020	-	97	47.059	Myotis_lucifugus
ENSG00000124256	ZBP1	96	51.415	ENSNGAG00000023407	Zbp1	96	53.066	Nannospalax_galili
ENSG00000124256	ZBP1	100	91.142	ENSNLEG00000007069	ZBP1	100	91.142	Nomascus_leucogenys
ENSG00000124256	ZBP1	90	60.352	ENSOGAG00000014671	ZBP1	100	55.990	Otolemur_garnettii
ENSG00000124256	ZBP1	91	55.947	ENSOARG00000017418	-	76	55.685	Ovis_aries
ENSG00000124256	ZBP1	100	97.436	ENSPPAG00000037949	ZBP1	100	97.436	Pan_paniscus
ENSG00000124256	ZBP1	92	60.870	ENSPPRG00000011275	-	98	60.776	Panthera_pardus
ENSG00000124256	ZBP1	92	62.174	ENSPTIG00000011495	-	98	62.069	Panthera_tigris_altaica
ENSG00000124256	ZBP1	100	97.902	ENSPTRG00000013665	ZBP1	100	97.902	Pan_troglodytes
ENSG00000124256	ZBP1	98	89.286	ENSPANG00000023211	ZBP1	100	89.286	Papio_anubis
ENSG00000124256	ZBP1	99	49.543	ENSPEMG00000016060	Zbp1	99	48.970	Peromyscus_maniculatus_bairdii
ENSG00000124256	ZBP1	100	94.406	ENSPPYG00000011165	ZBP1	100	94.406	Pongo_abelii
ENSG00000124256	ZBP1	97	61.205	ENSPCOG00000027415	ZBP1	98	60.964	Propithecus_coquereli
ENSG00000124256	ZBP1	88	57.339	ENSPVAG00000014691	-	96	54.201	Pteropus_vampyrus
ENSG00000124256	ZBP1	97	46.604	ENSRNOG00000006314	Zbp1	98	46.370	Rattus_norvegicus
ENSG00000124256	ZBP1	100	89.744	ENSRBIG00000044740	ZBP1	100	89.744	Rhinopithecus_bieti
ENSG00000124256	ZBP1	100	89.277	ENSRROG00000038526	ZBP1	100	89.277	Rhinopithecus_roxellana
ENSG00000124256	ZBP1	99	80.378	ENSSBOG00000032730	ZBP1	99	81.466	Saimiri_boliviensis_boliviensis
ENSG00000124256	ZBP1	91	62.115	ENSTBEG00000006578	ZBP1	100	60.218	Tupaia_belangeri
ENSG00000124256	ZBP1	91	58.850	ENSTTRG00000000687	-	95	53.353	Tursiops_truncatus
ENSG00000124256	ZBP1	90	61.607	ENSUAMG00000019777	ZBP1	83	58.760	Ursus_americanus
ENSG00000124256	ZBP1	99	54.167	ENSUMAG00000002600	ZBP1	95	53.935	Ursus_maritimus
ENSG00000124256	ZBP1	98	51.991	ENSVVUG00000017189	-	95	51.054	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003677	DNA binding	21873635.	IBA	Function
GO:0003677	DNA binding	17618271.	IDA	Function
GO:0003692	left-handed Z-DNA binding	11842111.	NAS	Function
GO:0003723	RNA binding	-	IEA	Function
GO:0003726	double-stranded RNA adenosine deaminase activity	-	IEA	Function
GO:0005515	protein binding	19590578.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	19158679.	IDA	Component
GO:0005737	cytoplasm	19158679.	IDA	Component
GO:0005829	cytosol	17618271.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0008150	biological_process	-	ND	Process
GO:0032479	regulation of type I interferon production	-	TAS	Process
GO:0032481	positive regulation of type I interferon production	-	TAS	Process
GO:0045087	innate immune response	-	IEA	Process
GO:0060340	positive regulation of type I interferon-mediated signaling pathway	21873635.	IBA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Input Drug :

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.