EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
25742747	An integrative approach identified genes associated with drug response in gastric cancer.	Carcinogenesis	2015 Apr	Zhou J	doi: 10.1093/carcin/bgv014
29535419	DEAD-box helicase 27 promotes colorectal cancer growth and metastasis and predicts poor survival in CRC patients.	Oncogene	2018 May	Tang J	doi: 10.1038/s41388-018-0196-1

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr20	49239310	Missense_Mutation	novel	Q654H	0.44
BLCA	chr20	49225160	Silent	rs765061022	L218L	0.07
BLCA	chr20	49221546	Missense_Mutation	rs780544787	T94M	0.49	ResIII
BLCA	chr20	49223267	Splice_Site	novel	X132_splice	0.41
BLCA	chr20	49242598	Missense_Mutation	NA	K738N	0.15
BLCA	chr20	49242621	Missense_Mutation	novel	S746F	0.43
BRCA	chr20	49242112	Silent	novel	L705L	0.09
BRCA	chr20	49223316	Nonsense_Mutation	NA	E148*	0.36	ResIII
BRCA	chr20	49223295	In_Frame_Del	novel	K142_E151del	0.11	ResIII
BRCA	chr20	49225141	Missense_Mutation	novel	S212F	0.04
BRCA	chr20	49235081	Missense_Mutation	novel	A505T	0.17
BRCA	chr20	49239252	Missense_Mutation	rs377559919	R635Q	0.22
BRCA	chr20	49219344	5'Flank	novel		0.4
BRCA	chr20	49226427	Splice_Region	novel		0.21
BRCA	chr20	49222997	Missense_Mutation	rs761824316	R125Q	0.24	ResIII
BRCA	chr20	49243831	Missense_Mutation	NA	K796N	0.18
CESC	chr20	49233679	Missense_Mutation	rs771190820	R446C	0.51
CESC	chr20	49224924	Intron	NA		0.23
CESC	chr20	49235087	Missense_Mutation	rs873434	R507W	0.36
CESC	chr20	49241967	Frame_Shift_Del	rs766714372	*K691Rfs4**	0.4
CESC	chr20	49219494	Missense_Mutation	novel	E47K	0.89
CESC	chr20	49222997	Missense_Mutation	rs761824316	R125Q	0.07	ResIII
COAD	chr20	49236499	Missense_Mutation	novel	I590T	0.22
COAD	chr20	49221502	Silent	novel	S79S	0.41
COAD	chr20	49226465	Silent	novel	P243P	0.5
COAD	chr20	49238971	Silent	novel	D601D	0.12
COAD	chr20	49242635	Nonsense_Mutation	NA	E751*	0.39
COAD	chr20	49236179	Missense_Mutation	NA	L517P	0.42
COAD	chr20	49228725	Silent	rs238166	A270A	0.26
COAD	chr20	49236415	Missense_Mutation	rs779990675	R562H	0.22
COAD	chr20	49228789	Missense_Mutation	rs761573110	V292M	0.38
COAD	chr20	49221532	Silent	novel	T89T	0.56
COAD	chr20	49224986	Nonsense_Mutation	novel	G201*	0.1
COAD	chr20	49243945	3'UTR	novel		0.2
COAD	chr20	49233330	Silent	NA	E383E	0.16
COAD	chr20	49243850	3'UTR	novel		0.07
COAD	chr20	49223281	Missense_Mutation	NA	K136T	0.33	ResIII
COAD	chr20	49234989	Missense_Mutation	novel	K474R	0.45
COAD	chr20	49235000	Missense_Mutation	rs759121430	R478C	0.21
COAD	chr20	49236152	Missense_Mutation	rs760415513	R508H	0.1
ESCA	chr20	49241967	Frame_Shift_Del	rs766714372	*K691Rfs4**	0.35
ESCA	chr20	49219328	5'Flank	novel		0.11
GBM	chr20	49228854	Frame_Shift_Ins	novel	*Q314Sfs28**	0.27
GBM	chr20	49243703	Missense_Mutation	novel	R791I	0.21
GBM	chr20	49242187	Missense_Mutation	novel	E730D	0.48
GBM	chr20	49228752	Silent	novel	R279R	0.25
HNSC	chr20	49238984	Frame_Shift_Del	novel	*E607Cfs7**	0.35
HNSC	chr20	49242112	Silent	novel	L705L	0.04
HNSC	chr20	49223287	Missense_Mutation	novel	G138E	0.31	ResIII
HNSC	chr20	49243860	3'UTR	novel		0.19
HNSC	chr20	49224968	Missense_Mutation	novel	K195E	0.37
HNSC	chr20	49236396	Missense_Mutation	novel	R556C	0.17
KIRC	chr20	49239337	Frame_Shift_Ins	novel	*I664Hfs15**	0.06
KIRC	chr20	49221467	Missense_Mutation	NA	G68R	0.31	ResIII
KIRP	chr20	49219391	Missense_Mutation	NA	E12D	0.29
LGG	chr20	49219448	Missense_Mutation	NA	N31K	0.46
LGG	chr20	49233623	Missense_Mutation	NA	S427N	0.29
LGG	chr20	49242110	Missense_Mutation	novel	L705I	0.05
LGG	chr20	49243911	3'UTR	novel		0.67
LUAD	chr20	49236193	Missense_Mutation	novel	V522L	0.13
LUAD	chr20	49233650	Missense_Mutation	novel	R436L	0.29
LUAD	chr20	49221474	Missense_Mutation	rs759277865	R70Q	0.19	ResIII
LUAD	chr20	49236498	Missense_Mutation	NA	I590V	0.14
LUAD	chr20	49219417	Missense_Mutation	rs779809768	V21G	0.35
LUAD	chr20	49235032	Silent	novel	L488L	0.08
LUAD	chr20	49225194	Missense_Mutation	novel	L230V	0.34
LUAD	chr20	49242090	Missense_Mutation	novel	E698G	0.15
LUAD	chr20	49219331	5'Flank	novel		0.21
LUAD	chr20	49221473	Nonsense_Mutation	rs558152082	R70*	0.24	ResIII
LUAD	chr20	49223376	Missense_Mutation	novel	D168Y	0.07	ResIII
LUAD	chr20	49236375	Missense_Mutation	novel	H549Y	0.06
LUAD	chr20	49225183	Missense_Mutation	NA	S226F	0.13
LUAD	chr20	49223011	Missense_Mutation	novel	T130S	0.1	ResIII
LUSC	chr20	49236424	Missense_Mutation	novel	S565F	0.23
LUSC	chr20	49242096	Missense_Mutation	novel	S700F	0.16
LUSC	chr20	49233669	Silent	novel	I442I	0.05
LUSC	chr20	49219403	Silent	rs150992243	A16A	0.38
LUSC	chr20	49219410	Nonsense_Mutation	NA	Q19*	0.22
LUSC	chr20	49230229	Missense_Mutation	novel	A335V	0.08
LUSC	chr20	49219335	5'Flank	novel		0.41
LUSC	chr20	49230242	Silent	novel	A339A	0.14
LUSC	chr20	49219503	Missense_Mutation	NA	V50L	0.29
LUSC	chr20	49221467	Missense_Mutation	novel	G68C	0.15	ResIII
OV	chr20	49243855	3'UTR	novel		0.53
OV	chr20	49242104	Nonsense_Mutation	novel	E703*	0.04
OV	chr20	49243858	3'UTR	novel		0.09
OV	chr20	49228875	Frame_Shift_Ins	novel	*C321Vfs21**	0.11
OV	chr20	49236465	In_Frame_Ins	novel	V579delinsASSWDYRHLPPLL	0.47
OV	chr20	49242105	Frame_Shift_Ins	novel	*E703Dfs18**	0.04
OV	chr20	49221590	Missense_Mutation	novel	K109Q	0.1	ResIII
PAAD	chr20	49219477	Missense_Mutation	novel	T41N	0.11
PRAD	chr20	49228770	Silent	NA	R285R	0.3
PRAD	chr20	49236152	Missense_Mutation	NA	R508L	0.07
PRAD	chr20	49233607	Missense_Mutation	rs753600780	R422W	0.05
READ	chr20	49243917	3'UTR	novel		0.06
READ	chr20	49243859	3'UTR	novel		0.42
READ	chr20	49243945	3'UTR	novel		0.41
READ	chr20	49243850	3'UTR	novel		0.13
READ	chr20	49243628	Splice_Site	NA	X766_splice	0.39
READ	chr20	49235072	Missense_Mutation	NA	R502W	0.44
READ	chr20	49222979	Missense_Mutation	NA	E119A	0.41	ResIII
SARC	chr20	49236252	Intron	novel		0.52
SKCM	chr20	49230257	Missense_Mutation	NA	I344M	0.17
SKCM	chr20	49242152	Missense_Mutation	rs767675958	R719C	0.37
SKCM	chr20	49219359	Missense_Mutation	NA	V2I	0.46
SKCM	chr20	49233670	Missense_Mutation	NA	R443W	0.1
SKCM	chr20	49242662	Silent	NA	L760L	0.43
SKCM	chr20	49233641	Missense_Mutation	novel	P433L	0.2
SKCM	chr20	49241967	Frame_Shift_Del	rs766714372	*K691Rfs4**	0.39
SKCM	chr20	49239297	Missense_Mutation	NA	R650K	0.42
SKCM	chr20	49236359	Silent	NA	T543T	0.22
SKCM	chr20	49242675	Missense_Mutation	novel	R764Q	0.15
SKCM	chr20	49242169	Silent	NA	A724A	0.18
SKCM	chr20	49233590	Missense_Mutation	rs267605978	S416F	0.28
SKCM	chr20	49226484	Missense_Mutation	rs768865635	P250S	0.1
SKCM	chr20	49236490	Missense_Mutation	NA	K587R	0.63
SKCM	chr20	49233690	Silent	novel	D449D	0.34
SKCM	chr20	49233691	Missense_Mutation	rs371321109	R450W	0.34
SKCM	chr20	49233660	Silent	NA	F439F	0.18
SKCM	chr20	49219345	5'Flank	novel		0.2
SKCM	chr20	49239282	Missense_Mutation	NA	V645A	0.18
SKCM	chr20	49219389	Missense_Mutation	NA	E12K	0.17
SKCM	chr20	49219345	5'Flank	novel		0.39
SKCM	chr20	49234998	Missense_Mutation	NA	H477R	0.25
SKCM	chr20	49222996	Nonsense_Mutation	NA	R125*	0.31	ResIII
SKCM	chr20	49230301	Missense_Mutation	novel	S359F	0.29
STAD	chr20	49221455	Frame_Shift_Del	novel	*I65Lfs41**	0.36	ResIII
STAD	chr20	49243884	3'UTR	novel		0.26
STAD	chr20	49235055	Missense_Mutation	NA	N496T	0.12
STAD	chr20	49241967	Frame_Shift_Del	rs766714372	*K691Rfs4**	0.4
STAD	chr20	49234948	Missense_Mutation	NA	R460S	0.26
STAD	chr20	49235068	Silent	novel	T500T	0.33
STAD	chr20	49236216	Silent	NA	I529I	0.05
STAD	chr20	49233623	Missense_Mutation	NA	S427N	0.1
STAD	chr20	49243639	Missense_Mutation	novel	E770Q	0.1
STAD	chr20	49239050	Missense_Mutation	novel	A628T	0.35
STAD	chr20	49226476	Missense_Mutation	novel	A247V	0.09
STAD	chr20	49226535	Missense_Mutation	novel	G267C	0.23
STAD	chr20	49241973	Missense_Mutation	novel	K691Q	0.16
STAD	chr20	49228751	Missense_Mutation	novel	R279H	0.28
STAD	chr20	49230271	Missense_Mutation	novel	R349Q	0.16
STAD	chr20	49241967	Frame_Shift_Del	rs766714372	*K691Rfs4**	0.32
THCA	chr20	49228806	Silent	NA	P297P	0.53
UCEC	chr20	49228726	Missense_Mutation	rs780574398	A271T	0.42
UCEC	chr20	49238946	Splice_Region	NA		0.28
UCEC	chr20	49242604	Silent	NA	Q740Q	0.26
UCEC	chr20	49243979	3'UTR	novel		0.26
UCEC	chr20	49243928	3'UTR	rs142292900		0.54
UCEC	chr20	49242134	Missense_Mutation	novel	R713W	0.11
UCEC	chr20	49236156	Missense_Mutation	novel	F509L	0.46
UCEC	chr20	49222996	Nonsense_Mutation	NA	R125*	0.43	ResIII
UCEC	chr20	49230258	Missense_Mutation	NA	A345T	0.43
UCEC	chr20	49236184	Missense_Mutation	novel	A519S	0.45
UCEC	chr20	49236382	Frame_Shift_Ins	novel	*R553Afs19**	0.4
UCEC	chr20	49233368	Missense_Mutation	rs749215203	R396H	0.45
UCEC	chr20	49233574	Missense_Mutation	rs140928753	D411Y	0.15
UCEC	chr20	49236373	Missense_Mutation	novel	V548A	0.21
UCEC	chr20	49236185	Missense_Mutation	novel	A519D	0.08
UCEC	chr20	49238957	Missense_Mutation	NA	L597F	0.53
UCEC	chr20	49243628	Splice_Site	NA	X766_splice	0.26
UCEC	chr20	49243888	3'UTR	novel		0.2
UCEC	chr20	49243676	Missense_Mutation	rs756848518	R782Q	0.41
UCEC	chr20	49241967	Frame_Shift_Del	rs766714372	*K691Rfs4**	0.44
UCEC	chr20	49242674	Nonsense_Mutation	rs764372955	R764*	0.17
UCEC	chr20	49243839	3'UTR	rs749469983		0.47
UCEC	chr20	49242635	Nonsense_Mutation	NA	E751*	0.44
UCEC	chr20	49241967	Frame_Shift_Del	rs766714372	*K691Rfs4**	0.43
UCEC	chr20	49221475	Silent	rs576621608	R70R	0.37
UCEC	chr20	49226478	Missense_Mutation	novel	C248R	0.46
UCEC	chr20	49241974	Missense_Mutation	novel	K691R	0.41
UCEC	chr20	49242607	Missense_Mutation	novel	K741N	0.42
UCEC	chr20	49239037	Missense_Mutation	novel	M623I	0.53
UCEC	chr20	49241967	Frame_Shift_Del	rs766714372	*K691Rfs4**	0.66
UCEC	chr20	49241966	Frame_Shift_Ins	novel	*E693Gfs11**	0.45
UCEC	chr20	49230268	Missense_Mutation	NA	G348D	0.09
UCEC	chr20	49233350	Missense_Mutation	novel	R390Q	0.44
UCEC	chr20	49230325	Missense_Mutation	novel	V367A	0.29
UCEC	chr20	49219335	5'Flank	novel		0.35
UCEC	chr20	49222997	Missense_Mutation	rs761824316	R125Q	0.19	ResIII
UCEC	chr20	49233350	Missense_Mutation	novel	R390Q	0.26
UCEC	chr20	49241967	Frame_Shift_Del	rs766714372	*K691Rfs4**	0.41
UCEC	chr20	49241975	Frame_Shift_Del	NA	*E693Rfs2**	0.29
UCEC	chr20	49221569	Missense_Mutation	novel	A102S	0.43	ResIII
UCEC	chr20	49241967	Frame_Shift_Del	rs766714372	*K691Rfs4**	0.41
UCEC	chr20	49235068	Silent	novel	T500T	0.28
UCEC	chr20	49230269	Silent	NA	G348G	0.25
UCEC	chr20	49242118	Silent	NA	A707A	0.37
UCEC	chr20	49225124	Frame_Shift_Ins	novel	E209*	0.33
UCEC	chr20	49226510	Silent	rs752181126	I258I	0.34
UCEC	chr20	49241967	Frame_Shift_Del	rs766714372	*K691Rfs4**	0.5
UCEC	chr20	49219366	Missense_Mutation	novel	A4V	0.23
UCEC	chr20	49228768	Missense_Mutation	rs202187886	R285C	0.53
UCEC	chr20	49236398	Silent	novel	R556R	0.11
UCEC	chr20	49243677	Silent	novel	R782R	0.16
UCEC	chr20	49241967	Frame_Shift_Del	rs766714372	*K691Rfs4**	0.44
UCEC	chr20	49241967	Frame_Shift_Del	rs766714372	*K691Rfs4**	0.35
UCEC	chr20	49219315	5'Flank	novel		0.17
UCEC	chr20	49243901	3'UTR	novel		0.29

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
LAML	DEL	0.0209	0.14746
LUAD	DEL	0.1085	0.18308
PRAD	AMP	0.0508	0.07085

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0039	Kaplan-Meier Survival Analysis
KIRC	0.0085	Kaplan-Meier Survival Analysis
ACC	0.0056	Kaplan-Meier Survival Analysis
SKCM	0.0025	Kaplan-Meier Survival Analysis
PRAD	0.0035	Kaplan-Meier Survival Analysis
LUSC	0.024	Kaplan-Meier Survival Analysis
KIRP	0.027	Kaplan-Meier Survival Analysis
CESC	0.03	Kaplan-Meier Survival Analysis
KICH	0.036	Kaplan-Meier Survival Analysis
UCEC	0.0001	Kaplan-Meier Survival Analysis
LIHC	0.0001	Kaplan-Meier Survival Analysis
LGG	0.00017	Kaplan-Meier Survival Analysis
THCA	0.022	Kaplan-Meier Survival Analysis
UVM	0.0023	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotype

GWAS

PPI

Paralog

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000124228 (Gene tree)
Gene ID: 55661
Gene Symbol: DDX27
Alias: dJ686N3.1|DRS1
Full Name: DEAD-box helicase 27
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Plus strand
Length: 24,783 bases
Position: chr20:49,219,295-49,244,077
Accession: 15837
Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein involved in the processing of 5.8S and 28S ribosomal RNAs. More specifically, the encoded protein localizes to the nucleolus, where it interacts with the PeBoW complex to ensure proper 3' end formation of 47S rRNA. [provided by RefSeq, Jan 2017]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000482680	ResIII	PF04851.15	6.3e-06	1	1
ENSP00000360828	ResIII	PF04851.15	6.7e-06	1	1
ENSP00000483495	ResIII	PF04851.15	6.7e-06	1	1
ENSP00000483119	ResIII	PF04851.15	0.00027	1	1
ENSP00000482680	DEAD	PF00270.29	3.5e-44	1	1
ENSP00000360828	DEAD	PF00270.29	4.5e-44	1	1
ENSP00000483495	DEAD	PF00270.29	4.5e-44	1	1
ENSP00000483119	DEAD	PF00270.29	1.1e-38	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	polyT & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	PolyT & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000471144	DDX27-203	3639	-	-	- (aa)	-	-
ENST00000462328	DDX27-202	824	-	ENSP00000481808	169 (aa)	-	A0A087WYH5
ENST00000493252	DDX27-205	825	-	ENSP00000483119	275 (aa)	-	A0A087X059
ENST00000484427	DDX27-204	4929	-	-	- (aa)	-	-
ENST00000618172	DDX27-206	2567	-	ENSP00000482680	765 (aa)	-	B7Z6D5
ENST00000622530	DDX27-207	2693	-	ENSP00000483495	796 (aa)	-	Q96GQ7
ENST00000371764	DDX27-201	2643	-	ENSP00000360828	796 (aa)	-	Q96GQ7

Gene Model

Click here to download 's gene model file

Phenotype

ensgID	Trait	pValue	Pubmed ID
ENSG00000124228	Attention Deficit Disorder with Hyperactivity	1.4180000E-004	18937294
ENSG00000124228	Iron	9.9810000E-004	19880490
ENSG00000124228	Iron	9.3510000E-004	19880490

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000124228	rs6125597	20	49224235	T	Intelligence (MTAG)	29326435	[0.016-0.028] unit increase	0.022382405	EFO_0004337
ENSG00000124228	rs6125597	20	49224235	T	Intelligence	29942086	z-score increase	6.909	EFO_0004337

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000124228's network

Paralog

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000124228	DDX27	85	35.593	ENSG00000105671	DDX49	93	40.171
ENSG00000124228	DDX27	86	31.667	ENSG00000198231	DDX42	51	34.865
ENSG00000124228	DDX27	82	30.769	ENSG00000067048	DDX3Y	57	35.248
ENSG00000124228	DDX27	99	38.235	ENSG00000123064	DDX54	93	46.667
ENSG00000124228	DDX27	78	38.028	ENSG00000089737	DDX24	51	39.062
ENSG00000124228	DDX27	87	34.146	ENSG00000125485	DDX31	55	31.325
ENSG00000124228	DDX27	84	32.618	ENSG00000080007	DDX43	56	36.512
ENSG00000124228	DDX27	84	32.520	ENSG00000107625	DDX50	55	33.255
ENSG00000124228	DDX27	82	31.174	ENSG00000215301	DDX3X	75	36.986
ENSG00000124228	DDX27	89	36.585	ENSG00000178105	DDX10	56	34.961
ENSG00000124228	DDX27	85	32.245	ENSG00000152670	DDX4	65	36.508
ENSG00000124228	DDX27	93	32.558	ENSG00000161960	EIF4A1	100	37.647
ENSG00000124228	DDX27	88	32.653	ENSG00000108654	DDX5	92	39.583
ENSG00000124228	DDX27	87	31.765	ENSG00000183258	DDX41	76	33.577
ENSG00000124228	DDX27	88	31.429	ENSG00000100201	DDX17	50	33.784
ENSG00000124228	DDX27	90	37.247	ENSG00000213782	DDX47	79	40.934
ENSG00000124228	DDX27	96	32.331	ENSG00000156976	EIF4A2	92	41.748
ENSG00000124228	DDX27	88	31.837	ENSG00000198563	DDX39B	80	38.095
ENSG00000124228	DDX27	57	33.333	ENSG00000157349	DDX19B	90	31.579
ENSG00000124228	DDX27	87	33.469	ENSG00000184735	DDX53	60	34.715
ENSG00000124228	DDX27	80	39.462	ENSG00000088205	DDX18	99	35.193
ENSG00000124228	DDX27	81	30.088	ENSG00000123136	DDX39A	93	32.222
ENSG00000124228	DDX27	52	33.562	ENSG00000109832	DDX25	86	30.159
ENSG00000124228	DDX27	85	30.932	ENSG00000110367	DDX6	73	30.833
ENSG00000124228	DDX27	84	32.922	ENSG00000111364	DDX55	85	37.126
ENSG00000124228	DDX27	88	34.426	ENSG00000118197	DDX59	70	34.848
ENSG00000124228	DDX27	87	35.102	ENSG00000136271	DDX56	97	40.556
ENSG00000124228	DDX27	84	30.738	ENSG00000165732	DDX21	52	32.723
ENSG00000124228	DDX27	57	36.364	ENSG00000182810	DDX28	68	31.536

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000124228	DDX27	99	70.288	ENSAPOG00000017645	ddx27	100	69.419	Acanthochromis_polyacanthus
ENSG00000124228	DDX27	99	95.238	ENSAMEG00000013627	DDX27	100	93.990	Ailuropoda_melanoleuca
ENSG00000124228	DDX27	94	75.581	ENSACIG00000014378	ddx27	96	80.628	Amphilophus_citrinellus
ENSG00000124228	DDX27	99	72.000	ENSAOCG00000021035	ddx27	100	69.419	Amphiprion_ocellaris
ENSG00000124228	DDX27	100	69.610	ENSAPEG00000022281	ddx27	100	69.290	Amphiprion_percula
ENSG00000124228	DDX27	94	75.290	ENSATEG00000010093	ddx27	99	68.164	Anabas_testudineus
ENSG00000124228	DDX27	99	79.636	ENSAPLG00000011377	DDX27	99	78.378	Anas_platyrhynchos
ENSG00000124228	DDX27	100	98.693	ENSANAG00000036257	DDX27	100	98.693	Aotus_nancymaae
ENSG00000124228	DDX27	99	74.182	ENSACLG00000014992	ddx27	100	70.505	Astatotilapia_calliptera
ENSG00000124228	DDX27	95	77.099	ENSAMXG00000000911	ddx27	100	72.774	Astyanax_mexicanus
ENSG00000124228	DDX27	100	95.033	ENSBTAG00000006671	DDX27	100	95.033	Bos_taurus
ENSG00000124228	DDX27	95	56.929	WBGene00022148	ddx-27	78	51.078	Caenorhabditis_elegans
ENSG00000124228	DDX27	100	97.908	ENSCJAG00000016135	DDX27	100	97.908	Callithrix_jacchus
ENSG00000124228	DDX27	99	94.980	ENSCAFG00000011384	DDX27	100	93.498	Canis_familiaris
ENSG00000124228	DDX27	99	94.980	ENSCAFG00020017143	DDX27	100	94.263	Canis_lupus_dingo
ENSG00000124228	DDX27	100	95.033	ENSCHIG00000007753	DDX27	100	95.033	Capra_hircus
ENSG00000124228	DDX27	100	95.948	ENSTSYG00000030362	DDX27	100	95.948	Carlito_syrichta
ENSG00000124228	DDX27	96	93.197	ENSCAPG00000010800	DDX27	99	92.916	Cavia_aperea
ENSG00000124228	DDX27	100	93.342	ENSCPOG00000002009	DDX27	100	93.081	Cavia_porcellus
ENSG00000124228	DDX27	100	98.562	ENSCCAG00000029782	DDX27	99	97.967	Cebus_capucinus
ENSG00000124228	DDX27	100	99.216	ENSCATG00000034832	DDX27	100	99.216	Cercocebus_atys
ENSG00000124228	DDX27	100	93.734	ENSCLAG00000008075	DDX27	100	93.473	Chinchilla_lanigera
ENSG00000124228	DDX27	100	99.216	ENSCSAG00000014996	DDX27	100	99.216	Chlorocebus_sabaeus
ENSG00000124228	DDX27	99	80.727	ENSCPBG00000026800	DDX27	98	79.818	Chrysemys_picta_bellii
ENSG00000124228	DDX27	95	62.692	ENSCING00000004235	-	99	55.163	Ciona_intestinalis
ENSG00000124228	DDX27	69	62.827	ENSCSAVG00000006949	-	99	63.211	Ciona_savignyi
ENSG00000124228	DDX27	100	93.856	ENSCANG00000038431	DDX27	99	93.470	Colobus_angolensis_palliatus
ENSG00000124228	DDX27	99	92.338	ENSCGRG00001015330	Ddx27	98	91.237	Cricetulus_griseus_chok1gshd
ENSG00000124228	DDX27	99	92.338	ENSCGRG00000008199	Ddx27	100	91.656	Cricetulus_griseus_crigri
ENSG00000124228	DDX27	95	75.479	ENSCSEG00000020260	ddx27	100	69.576	Cynoglossus_semilaevis
ENSG00000124228	DDX27	99	71.636	ENSCVAG00000011736	ddx27	100	70.194	Cyprinodon_variegatus
ENSG00000124228	DDX27	99	75.458	ENSDARG00000091831	ddx27	100	72.727	Danio_rerio
ENSG00000124228	DDX27	100	94.641	ENSDNOG00000019453	DDX27	99	93.401	Dasypus_novemcinctus
ENSG00000124228	DDX27	99	93.113	ENSDORG00000014137	Ddx27	100	92.680	Dipodomys_ordii
ENSG00000124228	DDX27	93	58.915	FBgn0021995	Rs1	59	62.179	Drosophila_melanogaster
ENSG00000124228	DDX27	90	78.374	ENSETEG00000018239	DDX27	92	78.665	Echinops_telfairi
ENSG00000124228	DDX27	96	71.103	ENSEBUG00000004326	ddx27	97	70.523	Eptatretus_burgeri
ENSG00000124228	DDX27	100	95.294	ENSEASG00005023342	DDX27	100	95.294	Equus_asinus_asinus
ENSG00000124228	DDX27	100	95.294	ENSECAG00000020963	DDX27	100	95.294	Equus_caballus
ENSG00000124228	DDX27	99	86.131	ENSEEUG00000012076	DDX27	78	91.525	Erinaceus_europaeus
ENSG00000124228	DDX27	99	74.545	ENSELUG00000014535	ddx27	100	72.194	Esox_lucius
ENSG00000124228	DDX27	100	95.953	ENSFCAG00000001448	DDX27	100	95.953	Felis_catus
ENSG00000124228	DDX27	95	81.679	ENSFALG00000004884	DDX27	98	80.194	Ficedula_albicollis
ENSG00000124228	DDX27	100	93.611	ENSFDAG00000018681	DDX27	100	92.829	Fukomys_damarensis
ENSG00000124228	DDX27	85	73.617	ENSFHEG00000006419	ddx27	85	81.457	Fundulus_heteroclitus
ENSG00000124228	DDX27	94	73.643	ENSGMOG00000016662	ddx27	83	71.765	Gadus_morhua
ENSG00000124228	DDX27	99	80.000	ENSGALG00000006974	DDX27	100	78.701	Gallus_gallus
ENSG00000124228	DDX27	94	73.256	ENSGAFG00000020344	ddx27	96	70.124	Gambusia_affinis
ENSG00000124228	DDX27	99	71.587	ENSGACG00000003177	ddx27	99	69.749	Gasterosteus_aculeatus
ENSG00000124228	DDX27	99	80.727	ENSGAGG00000001296	DDX27	100	79.818	Gopherus_agassizii
ENSG00000124228	DDX27	99	84.420	ENSGGOG00000015474	-	97	97.876	Gorilla_gorilla
ENSG00000124228	DDX27	99	74.182	ENSHBUG00000008119	ddx27	100	70.634	Haplochromis_burtoni
ENSG00000124228	DDX27	100	93.473	ENSHGLG00000008388	DDX27	100	93.081	Heterocephalus_glaber_female
ENSG00000124228	DDX27	100	93.473	ENSHGLG00100000130	DDX27	100	93.081	Heterocephalus_glaber_male
ENSG00000124228	DDX27	53	78.710	ENSHCOG00000015489	-	92	78.846	Hippocampus_comes
ENSG00000124228	DDX27	96	77.567	ENSIPUG00000024627	ddx27	100	71.934	Ictalurus_punctatus
ENSG00000124228	DDX27	99	92.848	ENSSTOG00000003645	DDX27	100	93.359	Ictidomys_tridecemlineatus
ENSG00000124228	DDX27	99	86.861	ENSJJAG00000009056	Ddx27	100	83.681	Jaculus_jaculus
ENSG00000124228	DDX27	99	69.908	ENSKMAG00000014889	ddx27	99	69.412	Kryptolebias_marmoratus
ENSG00000124228	DDX27	94	73.256	ENSLBEG00000022589	ddx27	100	68.336	Labrus_bergylta
ENSG00000124228	DDX27	99	79.636	ENSLACG00000011592	DDX27	100	76.419	Latimeria_chalumnae
ENSG00000124228	DDX27	99	74.482	ENSLOCG00000002659	ddx27	99	74.741	Lepisosteus_oculatus
ENSG00000124228	DDX27	100	93.856	ENSLAFG00000012190	DDX27	100	93.725	Loxodonta_africana
ENSG00000124228	DDX27	100	98.954	ENSMFAG00000045749	DDX27	100	98.954	Macaca_fascicularis
ENSG00000124228	DDX27	100	99.085	ENSMMUG00000023621	DDX27	100	99.085	Macaca_mulatta
ENSG00000124228	DDX27	100	99.085	ENSMNEG00000043931	DDX27	100	99.085	Macaca_nemestrina
ENSG00000124228	DDX27	100	96.732	ENSMLEG00000028160	DDX27	100	96.306	Mandrillus_leucophaeus
ENSG00000124228	DDX27	99	72.263	ENSMAMG00000009174	ddx27	99	66.223	Mastacembelus_armatus
ENSG00000124228	DDX27	99	74.182	ENSMZEG00005008750	ddx27	100	70.634	Maylandia_zebra
ENSG00000124228	DDX27	99	79.348	ENSMGAG00000008727	DDX27	99	81.647	Meleagris_gallopavo
ENSG00000124228	DDX27	99	92.857	ENSMAUG00000000552	Ddx27	100	92.689	Mesocricetus_auratus
ENSG00000124228	DDX27	100	96.340	ENSMICG00000002005	DDX27	100	96.340	Microcebus_murinus
ENSG00000124228	DDX27	99	92.450	ENSMOCG00000019594	Ddx27	100	91.895	Microtus_ochrogaster
ENSG00000124228	DDX27	99	72.894	ENSMMOG00000012754	ddx27	99	66.537	Mola_mola
ENSG00000124228	DDX27	100	89.673	ENSMODG00000016285	DDX27	100	89.673	Monodelphis_domestica
ENSG00000124228	DDX27	99	72.727	ENSMALG00000020942	ddx27	100	68.657	Monopterus_albus
ENSG00000124228	DDX27	99	92.318	MGP_CAROLIEiJ_G0024700	Ddx27	100	91.765	Mus_caroli
ENSG00000124228	DDX27	99	92.583	ENSMUSG00000017999	Ddx27	100	92.026	Mus_musculus
ENSG00000124228	DDX27	99	92.053	MGP_PahariEiJ_G0026142	Ddx27	100	91.503	Mus_pahari
ENSG00000124228	DDX27	99	92.848	MGP_SPRETEiJ_G0025620	Ddx27	100	92.288	Mus_spretus
ENSG00000124228	DDX27	100	93.081	ENSMPUG00000017572	DDX27	100	92.068	Mustela_putorius_furo
ENSG00000124228	DDX27	100	95.822	ENSMLUG00000003186	DDX27	100	95.698	Myotis_lucifugus
ENSG00000124228	DDX27	99	92.801	ENSNGAG00000023115	Ddx27	100	92.539	Nannospalax_galili
ENSG00000124228	DDX27	77	70.755	ENSNBRG00000006206	ddx27	84	65.761	Neolamprologus_brichardi
ENSG00000124228	DDX27	100	84.094	ENSNLEG00000006961	DDX27	99	84.567	Nomascus_leucogenys
ENSG00000124228	DDX27	100	84.837	ENSMEUG00000014412	DDX27	98	84.837	Notamacropus_eugenii
ENSG00000124228	DDX27	100	92.699	ENSOPRG00000014589	DDX27	99	92.258	Ochotona_princeps
ENSG00000124228	DDX27	99	92.725	ENSODEG00000006281	DDX27	100	92.428	Octodon_degus
ENSG00000124228	DDX27	99	74.182	ENSONIG00000019473	ddx27	100	70.490	Oreochromis_niloticus
ENSG00000124228	DDX27	99	83.444	ENSOANG00000006395	DDX27	97	83.660	Ornithorhynchus_anatinus
ENSG00000124228	DDX27	100	91.016	ENSOCUG00000016108	DDX27	98	90.347	Oryctolagus_cuniculus
ENSG00000124228	DDX27	99	73.897	ENSORLG00000013059	ddx27	100	69.666	Oryzias_latipes
ENSG00000124228	DDX27	99	74.265	ENSORLG00020021215	ddx27	100	70.596	Oryzias_latipes_hni
ENSG00000124228	DDX27	99	74.265	ENSORLG00015017588	ddx27	100	70.207	Oryzias_latipes_hsok
ENSG00000124228	DDX27	99	73.897	ENSOMEG00000023896	ddx27	99	70.452	Oryzias_melastigma
ENSG00000124228	DDX27	100	94.466	ENSOGAG00000002130	DDX27	100	93.436	Otolemur_garnettii
ENSG00000124228	DDX27	92	96.439	ENSOARG00000012345	DDX27	99	96.439	Ovis_aries
ENSG00000124228	DDX27	100	92.960	ENSPPAG00000035843	DDX27	94	99.708	Pan_paniscus
ENSG00000124228	DDX27	100	96.209	ENSPPRG00000006728	DDX27	100	96.209	Panthera_pardus
ENSG00000124228	DDX27	100	96.209	ENSPTIG00000011662	DDX27	100	96.209	Panthera_tigris_altaica
ENSG00000124228	DDX27	100	100.000	ENSPTRG00000013602	DDX27	100	99.874	Pan_troglodytes
ENSG00000124228	DDX27	100	91.906	ENSPANG00000000820	DDX27	100	92.167	Papio_anubis
ENSG00000124228	DDX27	99	71.942	ENSPKIG00000002802	ddx27	100	71.139	Paramormyrops_kingsleyae
ENSG00000124228	DDX27	99	79.137	ENSPSIG00000014493	DDX27	100	81.304	Pelodiscus_sinensis
ENSG00000124228	DDX27	99	71.533	ENSPMGG00000013002	ddx27	99	67.059	Periophthalmus_magnuspinnatus
ENSG00000124228	DDX27	99	91.921	ENSPEMG00000023215	Ddx27	100	91.373	Peromyscus_maniculatus_bairdii
ENSG00000124228	DDX27	94	76.357	ENSPMAG00000003094	ddx27	99	65.496	Petromyzon_marinus
ENSG00000124228	DDX27	94	84.170	ENSPCIG00000008052	DDX27	98	93.739	Phascolarctos_cinereus
ENSG00000124228	DDX27	99	71.739	ENSPFOG00000012217	ddx27	100	70.895	Poecilia_formosa
ENSG00000124228	DDX27	99	70.652	ENSPLAG00000005431	ddx27	100	69.537	Poecilia_latipinna
ENSG00000124228	DDX27	67	76.983	ENSPMEG00000005563	ddx27	99	76.983	Poecilia_mexicana
ENSG00000124228	DDX27	59	82.822	ENSPREG00000015596	ddx27	93	82.927	Poecilia_reticulata
ENSG00000124228	DDX27	100	99.085	ENSPPYG00000011113	DDX27	100	99.085	Pongo_abelii
ENSG00000124228	DDX27	100	95.822	ENSPCOG00000025327	DDX27	100	94.297	Propithecus_coquereli
ENSG00000124228	DDX27	100	96.601	ENSPVAG00000006308	DDX27	99	94.810	Pteropus_vampyrus
ENSG00000124228	DDX27	99	74.182	ENSPNYG00000014670	ddx27	98	71.518	Pundamilia_nyererei
ENSG00000124228	DDX27	98	76.667	ENSPNAG00000016043	ddx27	100	73.008	Pygocentrus_nattereri
ENSG00000124228	DDX27	99	92.980	ENSRNOG00000008081	Ddx27	100	92.288	Rattus_norvegicus
ENSG00000124228	DDX27	100	91.111	ENSRBIG00000024112	DDX27	100	90.955	Rhinopithecus_bieti
ENSG00000124228	DDX27	100	98.954	ENSRROG00000024811	DDX27	100	98.954	Rhinopithecus_roxellana
ENSG00000124228	DDX27	87	47.083	YLL008W	-	74	40.455	Saccharomyces_cerevisiae
ENSG00000124228	DDX27	100	98.824	ENSSBOG00000034281	DDX27	100	98.824	Saimiri_boliviensis_boliviensis
ENSG00000124228	DDX27	95	73.946	ENSSMAG00000006972	ddx27	99	69.063	Scophthalmus_maximus
ENSG00000124228	DDX27	99	73.529	ENSSDUG00000018855	ddx27	100	67.057	Seriola_dumerili
ENSG00000124228	DDX27	99	73.260	ENSSLDG00000004114	ddx27	100	68.886	Seriola_lalandi_dorsalis
ENSG00000124228	DDX27	95	81.679	ENSSPUG00000015687	DDX27	100	79.529	Sphenodon_punctatus
ENSG00000124228	DDX27	94	74.806	ENSSPAG00000007670	ddx27	100	68.614	Stegastes_partitus
ENSG00000124228	DDX27	100	95.294	ENSSSCG00000022915	DDX27	100	94.641	Sus_scrofa
ENSG00000124228	DDX27	96	81.818	ENSTGUG00000005649	DDX27	100	78.232	Taeniopygia_guttata
ENSG00000124228	DDX27	99	71.533	ENSTRUG00000002089	ddx27	100	66.437	Takifugu_rubripes
ENSG00000124228	DDX27	99	72.202	ENSTNIG00000002987	ddx27	100	68.394	Tetraodon_nigroviridis
ENSG00000124228	DDX27	100	87.451	ENSTBEG00000005320	DDX27	99	86.381	Tupaia_belangeri
ENSG00000124228	DDX27	100	94.248	ENSTTRG00000004288	DDX27	99	93.029	Tursiops_truncatus
ENSG00000124228	DDX27	99	86.861	ENSUAMG00000025519	DDX27	90	95.338	Ursus_americanus
ENSG00000124228	DDX27	99	95.238	ENSUMAG00000024473	DDX27	100	95.300	Ursus_maritimus
ENSG00000124228	DDX27	85	93.528	ENSVPAG00000001314	DDX27	89	93.528	Vicugna_pacos
ENSG00000124228	DDX27	99	94.723	ENSVVUG00000022331	DDX27	100	94.010	Vulpes_vulpes
ENSG00000124228	DDX27	99	75.197	ENSXETG00000017231	ddx27	99	75.131	Xenopus_tropicalis
ENSG00000124228	DDX27	99	71.795	ENSXCOG00000017180	ddx27	99	71.296	Xiphophorus_couchianus
ENSG00000124228	DDX27	99	70.652	ENSXMAG00000012284	ddx27	100	69.767	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0004386	helicase activity	-	IEA	Function
GO:0005515	protein binding	25825154.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005694	chromosome	20813266.	IDA	Component
GO:0005730	nucleolus	25825154.	IDA	Component
GO:0006364	rRNA processing	25825154.	IMP	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotype

GWAS

PPI

Paralog

Ortholog

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.