EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
22119546	Clinical proteomics identified ATP-dependent RNA helicase DDX39 as a novel biomarker to predict poor prognosis of patients with gastrointestinal stromal tumor.	J Proteomics	2012 Feb 2	Kikuta K	doi: 10.1016/j.jprot.2011.10.005
17548965	DDX39, upregulated in lung squamous cell cancer, displays RNA helicase activities and promotes cancer cell growth.	Cancer Biol Ther	2007 Jun	Sugiura T	-

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr19	14409412	Missense_Mutation	rs188717433	R337Q	0.26
BLCA	chr19	14409442	Missense_Mutation	novel	S327L	0.37
BLCA	chr19	14409132	Missense_Mutation	rs777641117	S391F	0.45
BLCA	chr19	14411068	Silent	rs142002555	L178L	0.12
BRCA	chr19	14409037	Missense_Mutation	NA	I423L	0.14
BRCA	chr19	14410986	Splice_Region	novel		0.22
BRCA	chr19	14413082	Missense_Mutation	rs754645617	R47W	0.27
BRCA	chr19	14413182	Nonsense_Mutation	NA	Y13*	0.12
CESC	chr19	14409911	Intron	NA		0.25
CESC	chr19	14409766	Silent	NA	L280L	0.11
CESC	chr19	14409379	Missense_Mutation	novel	R348Q	0.4
CESC	chr19	14409951	Intron	rs748916391		0.28
CESC	chr19	14411129	Missense_Mutation	novel	E158A	0.45
CESC	chr19	14409943	Intron	novel		0.36
CESC	chr19	14409828	Missense_Mutation	NA	G260S	0.5
COAD	chr19	14410244	Missense_Mutation	NA	R235Q	0.29
COAD	chr19	14413080	Silent	NA	R47R	0.13
COAD	chr19	14409442	Missense_Mutation	novel	S327L	0.21
COAD	chr19	14409634	Silent	rs371615674	F292F	0.35
COAD	chr19	14410278	Missense_Mutation	NA	M224V	0.41
COAD	chr19	14411539	Silent	novel	Y132Y	0.05
COAD	chr19	14411528	Missense_Mutation	NA	S136F	0.63
ESCA	chr19	14411598	Missense_Mutation	novel	V113L	0.08
ESCA	chr19	14411554	Missense_Mutation	novel	Q127H	0.22
ESCA	chr19	14409965	Intron	novel		0.12
GBM	chr19	14409053	Silent	rs148589157	I417I	0.19
HNSC	chr19	14409753	Missense_Mutation	novel	E285Q	0.32
HNSC	chr19	14410237	Silent	novel	V237V	0.3
KIRC	chr19	14411056	Missense_Mutation	novel	R182S	0.33
LIHC	chr19	14408893	3'UTR	novel		0.35
LUAD	chr19	14411546	Missense_Mutation	novel	K130R	0.76
LUSC	chr19	14409567	Missense_Mutation	rs141207973	A315T	0.15
LUSC	chr19	14413110	Silent	novel	S37S	0.13
LUSC	chr19	14409552	Frame_Shift_Del	novel	*M320Wfs66**	0.29
LUSC	chr19	14411585	Missense_Mutation	NA	V117A	0.1
OV	chr19	14408941	Silent	novel	R427R	0.09
OV	chr19	14411081	Missense_Mutation	NA	R174H	0.27
OV	chr19	14408870	3'UTR	novel		0.16
PAAD	chr19	14410218	Missense_Mutation	novel	D244N	0.2
PRAD	chr19	14412600	Missense_Mutation	rs374281705	A96V	0.07	ResIII
SKCM	chr19	14411528	Missense_Mutation	NA	S136F	0.35
SKCM	chr19	14409600	Nonsense_Mutation	NA	Q304*	0.42
SKCM	chr19	14409333	Missense_Mutation	novel	M363I	0.4
SKCM	chr19	14412593	Silent	rs774517231	F98F	0.42
SKCM	chr19	14411113	Silent	novel	N163N	0.17
SKCM	chr19	14411564	Missense_Mutation	NA	L124Q	0.37
SKCM	chr19	14410241	Missense_Mutation	NA	P236L	0.28
SKCM	chr19	14409920	Intron	novel		0.46
SKCM	chr19	14411061	Missense_Mutation	novel	N181D	0.22
STAD	chr19	14410330	Missense_Mutation	NA	M206I	0.2
STAD	chr19	14411068	Silent	rs142002555	L178L	0.16
STAD	chr19	14409077	Silent	NA	N409N	0.09
STAD	chr19	14409940	Intron	novel		0.46
STAD	chr19	14411528	Missense_Mutation	NA	S136F	0.2
STAD	chr19	14409816	Missense_Mutation	NA	Y264H	0.4
STAD	chr19	14412557	Missense_Mutation	novel	N110K	0.3
THCA	chr19	14412600	Missense_Mutation	rs374281705	A96V	0.21	ResIII
UCEC	chr19	14412579	Missense_Mutation	NA	L103Q	0.61	ResIII
UCEC	chr19	14412603	Missense_Mutation	novel	T95I	0.15	ResIII
UCEC	chr19	14419322	5'UTR	novel		0.48
UCEC	chr19	14409426	Silent	rs772264761	F332F	0.35
UCEC	chr19	14412593	Silent	rs774517231	F98F	0.35
UCEC	chr19	14411072	Missense_Mutation	NA	A177V	0.42
UCEC	chr19	14411158	Silent	NA	F148F	0.24
UCEC	chr19	14413182	Silent	rs191833585	Y13Y	0.22
UCEC	chr19	14419338	5'UTR	novel		0.11
UCEC	chr19	14413112	Missense_Mutation	novel	S37P	0.06
UCEC	chr19	14408901	3'UTR	novel		0.2
UCEC	chr19	14412637	Missense_Mutation	novel	V84I	0.37	ResIII
UCEC	chr19	14411071	Silent	rs775009962	A177A	0.43
UCEC	chr19	14413081	Missense_Mutation	rs753497125	R47Q	0.1
UCEC	chr19	14419316	5'UTR	novel		0.07
UCEC	chr19	14411533	Silent	novel	R134R	0.42
UCEC	chr19	14409567	Missense_Mutation	rs141207973	A315T	0.24
UCEC	chr19	14413092	Silent	novel	S43S	0.54
UCEC	chr19	14409829	Silent	rs556046710	H259H	0.34
UCEC	chr19	14410266	Missense_Mutation	novel	A228T	0.32
UCEC	chr19	14410309	Silent	novel	I213I	0.46
UCEC	chr19	14408923	3'UTR	novel		0.32
UCEC	chr19	14411101	Silent	rs767315372	V167V	0.61
UCEC	chr19	14410282	Silent	novel	Q222Q	0.06
UCEC	chr19	14409647	Splice_Site	novel	X289_splice	0.2
UCEC	chr19	14409964	Intron	rs760793832		0.41
UCEC	chr19	14409052	Missense_Mutation	novel	D418N	0.31
UCEC	chr19	14410240	Silent	NA	P236P	0.4
UCEC	chr19	14411506	Missense_Mutation	novel	K143N	0.3
UCEC	chr19	14412577	Nonsense_Mutation	NA	Q104*	0.26	ResIII
UCEC	chr19	14408876	3'UTR	novel		0.25
UCEC	chr19	14411072	Missense_Mutation	NA	A177V	0.26
UCEC	chr19	14411529	Missense_Mutation	novel	S136P	0.41
UCEC	chr19	14410329	Missense_Mutation	novel	R207W	0.25

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
READ	DEL	0.0848	0.23023
THCA	DEL	0.014	0.090402

Survival Analysis

Cancer	P-value	Q-value
THYM	0.005	Kaplan-Meier Survival Analysis
KIRC	0.00012	Kaplan-Meier Survival Analysis
STAD	0.0022	Kaplan-Meier Survival Analysis
MESO	0.0002	Kaplan-Meier Survival Analysis
SKCM	0.019	Kaplan-Meier Survival Analysis
LUSC	0.029	Kaplan-Meier Survival Analysis
ESCA	0.038	Kaplan-Meier Survival Analysis
KIRP	0.018	Kaplan-Meier Survival Analysis
BLCA	0.026	Kaplan-Meier Survival Analysis
CESC	0.0018	Kaplan-Meier Survival Analysis
LAML	0.014	Kaplan-Meier Survival Analysis
LIHC	0.00086	Kaplan-Meier Survival Analysis
DLBC	0.013	Kaplan-Meier Survival Analysis
LGG	0.0023	Kaplan-Meier Survival Analysis
UVM	0.00018	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

GWAS

PPI

Paralog

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000123136 (Gene tree)
Gene ID: 10212
Gene Symbol: DDX39A
Alias: DDXL|BAT1L|URH49|DDX39
Full Name: DExD-box helicase 39A
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Minus strand
Length: 10,586 bases
Position: chr19:14,408,798-14,419,383
Accession: 17821
Summary: This gene encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is thought to play a role in the prognosis of patients with gastrointestinal stromal tumors. A pseudogene of this gene is present on chromosome 13. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000392929	ResIII	PF04851.15	1.5e-05	1	1
ENSP00000467911	ResIII	PF04851.15	1.5e-05	1	1
ENSP00000242776	ResIII	PF04851.15	3.5e-05	1	1
ENSP00000392929	DEAD	PF00270.29	1.7e-38	1	1
ENSP00000467911	DEAD	PF00270.29	2e-38	1	1
ENSP00000242776	DEAD	PF00270.29	3.9e-38	1	1
ENSP00000467411	DEAD	PF00270.29	1e-27	1	1
ENSP00000466810	DEAD	PF00270.29	2.3e-11	1	1
ENSP00000464801	DEAD	PF00270.29	6.1e-10	1	1
ENSP00000465926	DEAD	PF00270.29	3.3e-07	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	polyT & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
16500893	RNA-binding of the human cytomegalovirus transactivator protein UL69, mediated by arginine-rich motifs, is not required for nuclear export of unspliced RNA.	Nucleic Acids Res	2006 Feb 25	Toth Z	-
11380625	The central MHC gene, BAT1, may encode a protein that down-regulates cytokine production.	Genes Cells	2001 May	Allcock RJ	-
17000901	The solution structure of REF2-I reveals interdomain interactions and regions involved in binding mRNA export factors and RNA.	RNA	2006 Nov	Golovanov AP	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000588542	DDX39A-207	1297	-	-	- (aa)	-	-
ENST00000454233	DDX39A-203	922	-	ENSP00000392929	267 (aa)	-	O00148
ENST00000587730	DDX39A-206	1813	-	-	- (aa)	-	-
ENST00000590315	DDX39A-213	566	-	ENSP00000467411	189 (aa)	-	K7EPJ3
ENST00000592632	DDX39A-218	586	-	-	- (aa)	-	-
ENST00000589318	DDX39A-209	1903	-	-	- (aa)	-	-
ENST00000586558	DDX39A-204	1127	-	-	- (aa)	-	-
ENST00000586993	DDX39A-205	585	-	ENSP00000464801	125 (aa)	-	K7EIL8
ENST00000592927	DDX39A-219	823	-	ENSP00000485838	96 (aa)	-	A0A0D9SEM9
ENST00000593026	DDX39A-221	657	-	-	- (aa)	-	-
ENST00000589675	DDX39A-210	829	-	ENSP00000467911	255 (aa)	-	K7EQN7
ENST00000590696	DDX39A-215	563	-	ENSP00000467040	92 (aa)	-	K7ENP6
ENST00000242776	DDX39A-201	1471	XM_006722606	ENSP00000242776	427 (aa)	XP_006722669	O00148
ENST00000590556	DDX39A-214	575	-	-	- (aa)	-	-
ENST00000324340	DDX39A-202	1355	-	ENSP00000322749	322 (aa)	-	O00148
ENST00000591275	DDX39A-216	484	-	ENSP00000465926	108 (aa)	-	K7EL56
ENST00000590260	DDX39A-212	988	-	-	- (aa)	-	-
ENST00000590239	DDX39A-211	565	-	ENSP00000466810	130 (aa)	-	K7EN69
ENST00000593008	DDX39A-220	538	-	-	- (aa)	-	-
ENST00000592391	DDX39A-217	1080	-	-	- (aa)	-	-
ENST00000588692	DDX39A-208	1478	-	ENSP00000467862	267 (aa)	-	O00148

Gene Model

Click here to download ENSG00000123136's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000123136	rs117111916	19	14418270	?	Mean corpuscular hemoglobin	30595370			EFO_0004527

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000123136's network

Paralog

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000123136	DDX39A	75	30.189	ENSG00000278053	DDX52	50	43.103
ENSG00000123136	DDX39A	93	32.222	ENSG00000124228	DDX27	81	30.088
ENSG00000123136	DDX39A	77	34.337	ENSG00000136271	DDX56	88	35.366
ENSG00000123136	DDX39A	94	31.868	ENSG00000168872	DDX19A	94	32.181
ENSG00000123136	DDX39A	92	30.682	ENSG00000123064	DDX54	94	30.653
ENSG00000123136	DDX39A	92	37.079	ENSG00000105671	DDX49	80	32.481
ENSG00000123136	DDX39A	82	30.084	ENSG00000109832	DDX25	94	42.188
ENSG00000123136	DDX39A	92	40.909	ENSG00000156976	EIF4A2	90	38.649
ENSG00000123136	DDX39A	95	39.560	ENSG00000110367	DDX6	82	36.591
ENSG00000123136	DDX39A	92	39.773	ENSG00000141543	EIF4A3	89	36.216
ENSG00000123136	DDX39A	97	39.785	ENSG00000067048	DDX3Y	61	30.807
ENSG00000123136	DDX39A	90	37.931	ENSG00000213782	DDX47	75	34.582
ENSG00000123136	DDX39A	97	39.785	ENSG00000215301	DDX3X	79	31.496
ENSG00000123136	DDX39A	94	30.208	ENSG00000111364	DDX55	85	30.675
ENSG00000123136	DDX39A	93	39.326	ENSG00000161960	EIF4A1	98	41.221
ENSG00000123136	DDX39A	100	89.953	ENSG00000198563	DDX39B	100	89.953
ENSG00000123136	DDX39A	98	34.375	ENSG00000088205	DDX18	52	30.618
ENSG00000123136	DDX39A	93	33.708	ENSG00000118197	DDX59	78	30.120
ENSG00000123136	DDX39A	94	31.868	ENSG00000157349	DDX19B	96	32.410
ENSG00000123136	DDX39A	91	35.632	ENSG00000198231	DDX42	51	31.016

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000123136	DDX39A	100	85.385	ENSAPOG00000009309	-	100	81.019	Acanthochromis_polyacanthus
ENSG00000123136	DDX39A	100	90.164	ENSAPOG00000013540	ddx39aa	100	90.164	Acanthochromis_polyacanthus
ENSG00000123136	DDX39A	100	97.658	ENSAMEG00000013379	DDX39A	98	97.658	Ailuropoda_melanoleuca
ENSG00000123136	DDX39A	100	90.421	ENSACIG00000007948	-	100	90.164	Amphilophus_citrinellus
ENSG00000123136	DDX39A	100	90.632	ENSACIG00000020898	DDX39A	100	90.632	Amphilophus_citrinellus
ENSG00000123136	DDX39A	100	90.398	ENSAOCG00000007403	-	100	90.398	Amphiprion_ocellaris
ENSG00000123136	DDX39A	100	90.398	ENSAOCG00000011728	DDX39A	100	90.398	Amphiprion_ocellaris
ENSG00000123136	DDX39A	100	90.398	ENSAPEG00000017193	-	100	90.398	Amphiprion_percula
ENSG00000123136	DDX39A	100	90.398	ENSAPEG00000001421	DDX39A	100	90.398	Amphiprion_percula
ENSG00000123136	DDX39A	100	91.121	ENSATEG00000012052	DDX39A	96	90.632	Anabas_testudineus
ENSG00000123136	DDX39A	100	91.355	ENSATEG00000004275	ddx39aa	100	90.867	Anabas_testudineus
ENSG00000123136	DDX39A	100	93.443	ENSACAG00000010756	DDX39A	100	93.443	Anolis_carolinensis
ENSG00000123136	DDX39A	100	98.595	ENSANAG00000036829	-	100	98.595	Aotus_nancymaae
ENSG00000123136	DDX39A	96	83.696	ENSANAG00000025403	-	99	72.770	Aotus_nancymaae
ENSG00000123136	DDX39A	100	90.421	ENSACLG00000001214	DDX39A	100	89.930	Astatotilapia_calliptera
ENSG00000123136	DDX39A	100	89.953	ENSACLG00000004945	-	100	89.696	Astatotilapia_calliptera
ENSG00000123136	DDX39A	100	88.993	ENSAMXG00000015256	-	100	88.993	Astyanax_mexicanus
ENSG00000123136	DDX39A	100	91.803	ENSAMXG00000018631	DDX39A	100	91.803	Astyanax_mexicanus
ENSG00000123136	DDX39A	100	96.487	ENSBTAG00000021820	DDX39A	100	96.487	Bos_taurus
ENSG00000123136	DDX39A	98	76.850	WBGene00001840	hel-1	99	76.134	Caenorhabditis_elegans
ENSG00000123136	DDX39A	100	99.074	ENSCJAG00000004760	DDX39A	100	97.378	Callithrix_jacchus
ENSG00000123136	DDX39A	100	97.892	ENSCAFG00000016355	DDX39A	100	97.892	Canis_familiaris
ENSG00000123136	DDX39A	100	97.892	ENSCAFG00020007399	DDX39A	100	97.892	Canis_lupus_dingo
ENSG00000123136	DDX39A	100	96.721	ENSCHIG00000019059	DDX39A	100	96.721	Capra_hircus
ENSG00000123136	DDX39A	100	97.658	ENSTSYG00000030248	DDX39A	100	97.658	Carlito_syrichta
ENSG00000123136	DDX39A	100	96.721	ENSCAPG00000010901	DDX39A	100	96.721	Cavia_aperea
ENSG00000123136	DDX39A	100	96.487	ENSCPOG00000008615	DDX39A	100	96.487	Cavia_porcellus
ENSG00000123136	DDX39A	100	99.297	ENSCCAG00000034932	DDX39A	100	99.297	Cebus_capucinus
ENSG00000123136	DDX39A	100	100.000	ENSCATG00000044440	DDX39A	100	100.000	Cercocebus_atys
ENSG00000123136	DDX39A	100	96.487	ENSCLAG00000015069	DDX39A	100	96.487	Chinchilla_lanigera
ENSG00000123136	DDX39A	100	100.000	ENSCSAG00000006342	DDX39A	100	100.000	Chlorocebus_sabaeus
ENSG00000123136	DDX39A	100	89.231	ENSCPBG00000011879	DDX39A	100	89.019	Chrysemys_picta_bellii
ENSG00000123136	DDX39A	91	88.689	ENSCING00000005175	-	98	86.091	Ciona_intestinalis
ENSG00000123136	DDX39A	92	88.579	ENSCSAVG00000002162	-	98	85.851	Ciona_savignyi
ENSG00000123136	DDX39A	100	100.000	ENSCANG00000037031	-	100	100.000	Colobus_angolensis_palliatus
ENSG00000123136	DDX39A	100	98.913	ENSCANG00000034172	-	100	96.721	Colobus_angolensis_palliatus
ENSG00000123136	DDX39A	100	97.222	ENSCGRG00001001611	Ddx39	100	96.721	Cricetulus_griseus_chok1gshd
ENSG00000123136	DDX39A	100	97.222	ENSCGRG00000014915	Ddx39	100	96.721	Cricetulus_griseus_crigri
ENSG00000123136	DDX39A	100	88.525	ENSCSEG00000003434	ddx39aa	100	88.525	Cynoglossus_semilaevis
ENSG00000123136	DDX39A	100	89.696	ENSCSEG00000015474	DDX39A	99	89.696	Cynoglossus_semilaevis
ENSG00000123136	DDX39A	100	84.259	ENSCVAG00000005146	-	94	98.039	Cyprinodon_variegatus
ENSG00000123136	DDX39A	100	89.461	ENSCVAG00000007477	DDX39A	100	89.461	Cyprinodon_variegatus
ENSG00000123136	DDX39A	100	91.101	ENSDARG00000006225	ddx39aa	100	91.101	Danio_rerio
ENSG00000123136	DDX39A	100	91.803	ENSDARG00000015111	ddx39ab	100	91.803	Danio_rerio
ENSG00000123136	DDX39A	100	94.565	ENSDNOG00000049340	DDX39A	91	77.000	Dasypus_novemcinctus
ENSG00000123136	DDX39A	100	96.487	ENSDORG00000013041	Ddx39	100	96.487	Dipodomys_ordii
ENSG00000123136	DDX39A	99	82.824	FBgn0014189	Hel25E	99	82.824	Drosophila_melanogaster
ENSG00000123136	DDX39A	100	93.519	ENSETEG00000016559	DDX39A	99	81.991	Echinops_telfairi
ENSG00000123136	DDX39A	100	89.486	ENSEBUG00000010042	ddx39aa	98	89.252	Eptatretus_burgeri
ENSG00000123136	DDX39A	100	97.658	ENSEASG00005015272	DDX39A	100	97.658	Equus_asinus_asinus
ENSG00000123136	DDX39A	100	97.658	ENSECAG00000040285	DDX39A	100	97.658	Equus_caballus
ENSG00000123136	DDX39A	99	90.995	ENSEEUG00000015035	DDX39A	100	90.995	Erinaceus_europaeus
ENSG00000123136	DDX39A	100	91.101	ENSELUG00000010581	DDX39A	100	90.632	Esox_lucius
ENSG00000123136	DDX39A	100	91.101	ENSELUG00000006779	-	91	90.995	Esox_lucius
ENSG00000123136	DDX39A	100	97.892	ENSFCAG00000013488	DDX39A	100	97.892	Felis_catus
ENSG00000123136	DDX39A	100	96.956	ENSFDAG00000014649	DDX39A	100	96.956	Fukomys_damarensis
ENSG00000123136	DDX39A	100	89.953	ENSFHEG00000009716	-	100	89.461	Fundulus_heteroclitus
ENSG00000123136	DDX39A	100	90.187	ENSFHEG00000002643	ddx39aa	100	89.930	Fundulus_heteroclitus
ENSG00000123136	DDX39A	93	90.977	ENSGMOG00000011287	-	97	89.336	Gadus_morhua
ENSG00000123136	DDX39A	99	90.758	ENSGMOG00000014316	DDX39A	99	90.758	Gadus_morhua
ENSG00000123136	DDX39A	100	85.321	ENSGAFG00000014768	-	100	83.372	Gambusia_affinis
ENSG00000123136	DDX39A	100	89.953	ENSGAFG00000010170	ddx39aa	100	89.696	Gambusia_affinis
ENSG00000123136	DDX39A	100	89.930	ENSGACG00000006096	DDX39A	100	89.930	Gasterosteus_aculeatus
ENSG00000123136	DDX39A	100	90.187	ENSGACG00000019335	ddx39aa	100	89.930	Gasterosteus_aculeatus
ENSG00000123136	DDX39A	100	93.911	ENSGAGG00000007527	DDX39A	100	93.911	Gopherus_agassizii
ENSG00000123136	DDX39A	100	100.000	ENSGGOG00000005414	DDX39A	100	100.000	Gorilla_gorilla
ENSG00000123136	DDX39A	100	90.421	ENSHBUG00000020257	DDX39A	100	89.930	Haplochromis_burtoni
ENSG00000123136	DDX39A	100	89.953	ENSHBUG00000003748	ddx39aa	100	89.696	Haplochromis_burtoni
ENSG00000123136	DDX39A	100	96.253	ENSHGLG00000018263	DDX39A	100	96.253	Heterocephalus_glaber_female
ENSG00000123136	DDX39A	99	91.943	ENSHGLG00100007165	DDX39A	93	91.943	Heterocephalus_glaber_male
ENSG00000123136	DDX39A	100	88.290	ENSHCOG00000018674	ddx39aa	100	88.290	Hippocampus_comes
ENSG00000123136	DDX39A	100	87.822	ENSHCOG00000009111	-	100	87.822	Hippocampus_comes
ENSG00000123136	DDX39A	100	91.335	ENSIPUG00000021552	ddx39aa	100	91.335	Ictalurus_punctatus
ENSG00000123136	DDX39A	100	91.101	ENSIPUG00000021341	DDX39A	100	91.101	Ictalurus_punctatus
ENSG00000123136	DDX39A	100	97.892	ENSSTOG00000013762	DDX39A	100	97.892	Ictidomys_tridecemlineatus
ENSG00000123136	DDX39A	99	83.688	ENSJJAG00000017826	-	96	83.688	Jaculus_jaculus
ENSG00000123136	DDX39A	100	96.019	ENSJJAG00000004337	-	100	96.019	Jaculus_jaculus
ENSG00000123136	DDX39A	100	90.421	ENSKMAG00000000831	-	100	90.164	Kryptolebias_marmoratus
ENSG00000123136	DDX39A	99	89.647	ENSKMAG00000011231	DDX39A	96	89.151	Kryptolebias_marmoratus
ENSG00000123136	DDX39A	100	88.525	ENSLBEG00000002817	DDX39A	95	88.525	Labrus_bergylta
ENSG00000123136	DDX39A	100	88.525	ENSLBEG00000025618	-	100	88.525	Labrus_bergylta
ENSG00000123136	DDX39A	100	92.740	ENSLACG00000015063	DDX39A	100	92.506	Latimeria_chalumnae
ENSG00000123136	DDX39A	100	92.272	ENSLOCG00000006534	DDX39A	100	92.272	Lepisosteus_oculatus
ENSG00000123136	DDX39A	100	96.956	ENSLAFG00000022777	DDX39A	100	96.956	Loxodonta_africana
ENSG00000123136	DDX39A	100	100.000	ENSMFAG00000044174	DDX39A	100	100.000	Macaca_fascicularis
ENSG00000123136	DDX39A	100	100.000	ENSMMUG00000005723	DDX39A	100	100.000	Macaca_mulatta
ENSG00000123136	DDX39A	100	100.000	ENSMNEG00000044292	DDX39A	100	100.000	Macaca_nemestrina
ENSG00000123136	DDX39A	100	100.000	ENSMLEG00000007602	DDX39A	100	100.000	Mandrillus_leucophaeus
ENSG00000123136	DDX39A	100	90.867	ENSMAMG00000000971	ddx39aa	100	90.867	Mastacembelus_armatus
ENSG00000123136	DDX39A	100	90.398	ENSMAMG00000009916	DDX39A	100	90.398	Mastacembelus_armatus
ENSG00000123136	DDX39A	100	90.421	ENSMZEG00005002864	DDX39A	100	89.930	Maylandia_zebra
ENSG00000123136	DDX39A	100	89.953	ENSMZEG00005023935	ddx39aa	100	89.696	Maylandia_zebra
ENSG00000123136	DDX39A	100	97.222	ENSMAUG00000008459	Ddx39	100	96.721	Mesocricetus_auratus
ENSG00000123136	DDX39A	100	97.892	ENSMICG00000015325	DDX39A	100	97.892	Microcebus_murinus
ENSG00000123136	DDX39A	100	97.222	ENSMOCG00000016890	Ddx39	92	96.682	Microtus_ochrogaster
ENSG00000123136	DDX39A	100	88.525	ENSMMOG00000006328	DDX39A	100	88.525	Mola_mola
ENSG00000123136	DDX39A	100	90.867	ENSMMOG00000008895	-	100	90.867	Mola_mola
ENSG00000123136	DDX39A	100	95.316	ENSMODG00000002448	DDX39A	88	95.316	Monodelphis_domestica
ENSG00000123136	DDX39A	100	90.398	ENSMALG00000002697	DDX39A	100	90.398	Monopterus_albus
ENSG00000123136	DDX39A	100	90.867	ENSMALG00000022576	ddx39aa	100	90.867	Monopterus_albus
ENSG00000123136	DDX39A	100	97.222	MGP_CAROLIEiJ_G0031277	Ddx39	100	97.190	Mus_caroli
ENSG00000123136	DDX39A	100	97.222	ENSMUSG00000005481	Ddx39	100	97.190	Mus_musculus
ENSG00000123136	DDX39A	100	97.222	MGP_PahariEiJ_G0022883	Ddx39	100	97.190	Mus_pahari
ENSG00000123136	DDX39A	100	97.222	MGP_SPRETEiJ_G0032396	Ddx39	100	97.190	Mus_spretus
ENSG00000123136	DDX39A	100	97.190	ENSMPUG00000003051	DDX39A	100	97.190	Mustela_putorius_furo
ENSG00000123136	DDX39A	100	93.846	ENSMLUG00000028448	-	99	94.601	Myotis_lucifugus
ENSG00000123136	DDX39A	100	91.667	ENSMLUG00000029622	-	99	90.164	Myotis_lucifugus
ENSG00000123136	DDX39A	100	91.200	ENSMLUG00000000939	-	100	90.632	Myotis_lucifugus
ENSG00000123136	DDX39A	100	97.424	ENSMLUG00000009280	-	98	97.424	Myotis_lucifugus
ENSG00000123136	DDX39A	100	92.000	ENSMLUG00000026217	-	99	92.723	Myotis_lucifugus
ENSG00000123136	DDX39A	96	93.478	ENSMLUG00000013597	-	99	83.726	Myotis_lucifugus
ENSG00000123136	DDX39A	100	96.487	ENSNGAG00000010734	Ddx39	100	96.487	Nannospalax_galili
ENSG00000123136	DDX39A	100	89.953	ENSNBRG00000001661	ddx39aa	100	89.696	Neolamprologus_brichardi
ENSG00000123136	DDX39A	100	90.421	ENSNBRG00000010679	DDX39A	100	89.930	Neolamprologus_brichardi
ENSG00000123136	DDX39A	100	100.000	ENSNLEG00000013515	DDX39A	100	92.974	Nomascus_leucogenys
ENSG00000123136	DDX39A	100	91.667	ENSMEUG00000005450	DDX39A	100	81.991	Notamacropus_eugenii
ENSG00000123136	DDX39A	98	91.489	ENSODEG00000017817	-	100	89.461	Octodon_degus
ENSG00000123136	DDX39A	100	94.614	ENSODEG00000009068	-	100	94.614	Octodon_degus
ENSG00000123136	DDX39A	96	82.609	ENSODEG00000001453	-	100	77.315	Octodon_degus
ENSG00000123136	DDX39A	100	95.785	ENSODEG00000019523	-	100	95.785	Octodon_degus
ENSG00000123136	DDX39A	100	89.953	ENSONIG00000018177	ddx39aa	100	89.696	Oreochromis_niloticus
ENSG00000123136	DDX39A	100	90.421	ENSONIG00000008122	DDX39A	100	89.930	Oreochromis_niloticus
ENSG00000123136	DDX39A	96	84.783	ENSOANG00000005137	DDX39A	95	77.857	Ornithorhynchus_anatinus
ENSG00000123136	DDX39A	96	76.087	ENSOCUG00000002496	DDX39A	100	69.252	Oryctolagus_cuniculus
ENSG00000123136	DDX39A	100	89.953	ENSORLG00000000279	ddx39aa	100	89.696	Oryzias_latipes
ENSG00000123136	DDX39A	100	89.227	ENSORLG00000010565	DDX39A	100	89.227	Oryzias_latipes
ENSG00000123136	DDX39A	100	89.953	ENSORLG00020019315	ddx39aa	100	89.696	Oryzias_latipes_hni
ENSG00000123136	DDX39A	100	89.227	ENSORLG00020004181	DDX39A	100	89.227	Oryzias_latipes_hni
ENSG00000123136	DDX39A	100	89.227	ENSORLG00015000447	-	100	89.227	Oryzias_latipes_hsok
ENSG00000123136	DDX39A	100	89.953	ENSORLG00015019274	ddx39aa	100	89.696	Oryzias_latipes_hsok
ENSG00000123136	DDX39A	100	89.227	ENSOMEG00000009789	-	100	89.227	Oryzias_melastigma
ENSG00000123136	DDX39A	100	89.720	ENSOMEG00000010444	ddx39aa	100	89.461	Oryzias_melastigma
ENSG00000123136	DDX39A	100	90.000	ENSOGAG00000029626	-	99	88.028	Otolemur_garnettii
ENSG00000123136	DDX39A	96	89.130	ENSOGAG00000025638	-	99	86.461	Otolemur_garnettii
ENSG00000123136	DDX39A	100	97.892	ENSOGAG00000010280	-	100	97.892	Otolemur_garnettii
ENSG00000123136	DDX39A	100	96.721	ENSOARG00000005744	DDX39A	91	96.721	Ovis_aries
ENSG00000123136	DDX39A	100	100.000	ENSPPAG00000040065	DDX39A	100	100.000	Pan_paniscus
ENSG00000123136	DDX39A	100	97.892	ENSPPRG00000003506	DDX39A	100	97.892	Panthera_pardus
ENSG00000123136	DDX39A	100	97.892	ENSPTIG00000017287	DDX39A	100	97.892	Panthera_tigris_altaica
ENSG00000123136	DDX39A	100	100.000	ENSPTRG00000010590	DDX39A	100	100.000	Pan_troglodytes
ENSG00000123136	DDX39A	100	100.000	ENSPTRG00000042673	-	100	100.000	Pan_troglodytes
ENSG00000123136	DDX39A	100	100.000	ENSPANG00000015036	DDX39A	100	100.000	Papio_anubis
ENSG00000123136	DDX39A	100	92.290	ENSPKIG00000006284	DDX39A	100	91.569	Paramormyrops_kingsleyae
ENSG00000123136	DDX39A	100	92.037	ENSPKIG00000007272	-	100	92.037	Paramormyrops_kingsleyae
ENSG00000123136	DDX39A	91	91.954	ENSPSIG00000011417	DDX39A	100	96.129	Pelodiscus_sinensis
ENSG00000123136	DDX39A	99	89.623	ENSPMGG00000021765	-	97	89.623	Periophthalmus_magnuspinnatus
ENSG00000123136	DDX39A	100	90.654	ENSPMGG00000016520	DDX39A	100	90.164	Periophthalmus_magnuspinnatus
ENSG00000123136	DDX39A	100	87.963	ENSPEMG00000014184	-	99	81.560	Peromyscus_maniculatus_bairdii
ENSG00000123136	DDX39A	100	96.296	ENSPEMG00000017767	-	100	96.253	Peromyscus_maniculatus_bairdii
ENSG00000123136	DDX39A	100	85.385	ENSPMAG00000009017	ddx39aa	100	82.751	Petromyzon_marinus
ENSG00000123136	DDX39A	100	95.550	ENSPCIG00000029788	DDX39A	100	95.550	Phascolarctos_cinereus
ENSG00000123136	DDX39A	100	89.953	ENSPFOG00000010070	DDX39A	100	89.461	Poecilia_formosa
ENSG00000123136	DDX39A	100	89.720	ENSPFOG00000000914	ddx39aa	100	89.461	Poecilia_formosa
ENSG00000123136	DDX39A	100	89.953	ENSPLAG00000009821	DDX39A	100	89.461	Poecilia_latipinna
ENSG00000123136	DDX39A	100	89.720	ENSPLAG00000008645	-	100	89.461	Poecilia_latipinna
ENSG00000123136	DDX39A	100	89.720	ENSPMEG00000021471	-	100	89.461	Poecilia_mexicana
ENSG00000123136	DDX39A	100	89.720	ENSPMEG00000010187	DDX39A	100	89.227	Poecilia_mexicana
ENSG00000123136	DDX39A	100	90.187	ENSPREG00000017406	ddx39aa	100	89.930	Poecilia_reticulata
ENSG00000123136	DDX39A	100	89.720	ENSPREG00000013989	DDX39A	100	89.227	Poecilia_reticulata
ENSG00000123136	DDX39A	100	100.000	ENSPPYG00000009642	DDX39A	100	100.000	Pongo_abelii
ENSG00000123136	DDX39A	100	94.444	ENSPCAG00000005768	DDX39A	100	77.986	Procavia_capensis
ENSG00000123136	DDX39A	100	97.190	ENSPCOG00000024047	-	100	97.190	Propithecus_coquereli
ENSG00000123136	DDX39A	100	95.370	ENSPCOG00000027926	-	100	95.082	Propithecus_coquereli
ENSG00000123136	DDX39A	100	97.658	ENSPVAG00000006950	DDX39A	100	97.658	Pteropus_vampyrus
ENSG00000123136	DDX39A	100	89.953	ENSPNYG00000016438	-	100	89.696	Pundamilia_nyererei
ENSG00000123136	DDX39A	100	90.421	ENSPNYG00000001498	DDX39A	100	89.930	Pundamilia_nyererei
ENSG00000123136	DDX39A	100	91.803	ENSPNAG00000014271	DDX39A	100	91.803	Pygocentrus_nattereri
ENSG00000123136	DDX39A	100	90.164	ENSPNAG00000022623	-	100	90.164	Pygocentrus_nattereri
ENSG00000123136	DDX39A	100	96.721	ENSRNOG00000004373	Ddx39a	100	96.721	Rattus_norvegicus
ENSG00000123136	DDX39A	100	100.000	ENSRBIG00000036352	DDX39A	100	100.000	Rhinopithecus_bieti
ENSG00000123136	DDX39A	100	100.000	ENSRROG00000027985	DDX39A	100	100.000	Rhinopithecus_roxellana
ENSG00000123136	DDX39A	100	98.595	ENSSBOG00000034939	DDX39A	100	98.595	Saimiri_boliviensis_boliviensis
ENSG00000123136	DDX39A	100	95.785	ENSSHAG00000005494	DDX39A	100	95.785	Sarcophilus_harrisii
ENSG00000123136	DDX39A	100	91.335	ENSSFOG00015005701	DDX39A	100	91.335	Scleropages_formosus
ENSG00000123136	DDX39A	100	92.272	ENSSFOG00015007928	ddx39a	100	92.272	Scleropages_formosus
ENSG00000123136	DDX39A	100	90.398	ENSSMAG00000002831	DDX39A	100	90.398	Scophthalmus_maximus
ENSG00000123136	DDX39A	100	89.696	ENSSMAG00000016567	ddx39aa	100	89.696	Scophthalmus_maximus
ENSG00000123136	DDX39A	100	91.355	ENSSDUG00000020224	ddx39aa	100	90.867	Seriola_dumerili
ENSG00000123136	DDX39A	100	84.259	ENSSDUG00000023694	-	100	77.344	Seriola_dumerili
ENSG00000123136	DDX39A	96	89.130	ENSSDUG00000009075	DDX39A	100	93.064	Seriola_dumerili
ENSG00000123136	DDX39A	96	89.130	ENSSLDG00000002882	-	100	92.775	Seriola_lalandi_dorsalis
ENSG00000123136	DDX39A	100	90.632	ENSSLDG00000017643	DDX39A	100	90.632	Seriola_lalandi_dorsalis
ENSG00000123136	DDX39A	100	87.156	ENSSLDG00000010812	-	88	82.906	Seriola_lalandi_dorsalis
ENSG00000123136	DDX39A	94	69.327	ENSSLDG00000006386	-	96	69.849	Seriola_lalandi_dorsalis
ENSG00000123136	DDX39A	100	90.398	ENSSPAG00000019372	DDX39A	100	90.398	Stegastes_partitus
ENSG00000123136	DDX39A	100	90.398	ENSSPAG00000006186	-	100	90.398	Stegastes_partitus
ENSG00000123136	DDX39A	100	83.206	ENSTRUG00000019985	-	99	83.173	Takifugu_rubripes
ENSG00000123136	DDX39A	97	80.645	ENSTRUG00000000807	-	94	73.900	Takifugu_rubripes
ENSG00000123136	DDX39A	100	91.121	ENSTRUG00000022930	DDX39A	100	90.632	Takifugu_rubripes
ENSG00000123136	DDX39A	100	96.956	ENSTTRG00000007931	DDX39A	100	96.956	Tursiops_truncatus
ENSG00000123136	DDX39A	100	97.658	ENSUAMG00000020022	DDX39A	100	97.658	Ursus_americanus
ENSG00000123136	DDX39A	100	97.917	ENSUMAG00000004317	DDX39A	99	97.658	Ursus_maritimus
ENSG00000123136	DDX39A	100	97.892	ENSVVUG00000026939	DDX39A	100	97.892	Vulpes_vulpes
ENSG00000123136	DDX39A	100	90.164	ENSXETG00000020607	ddx39a	99	90.164	Xenopus_tropicalis
ENSG00000123136	DDX39A	100	89.227	ENSXCOG00000015586	DDX39A	100	89.227	Xiphophorus_couchianus
ENSG00000123136	DDX39A	100	89.953	ENSXMAG00000006547	ddx39aa	100	89.696	Xiphophorus_maculatus
ENSG00000123136	DDX39A	100	89.720	ENSXMAG00000008939	DDX39A	100	89.227	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000398	mRNA splicing, via spliceosome	15047853.	IGI	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0004386	helicase activity	-	IEA	Function
GO:0005515	protein binding	14667819.15047853.16189514.21044950.21859714.23652018.25416956.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	21859714.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	21859714.	IDA	Component
GO:0006405	RNA export from nucleus	-	TAS	Process
GO:0006406	mRNA export from nucleus	15047853.	IGI	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0016607	nuclear speck	-	IDA	Component
GO:0016887	ATPase activity	20844015.	EXP	Function
GO:0031124	mRNA 3'-end processing	-	TAS	Process
GO:0042802	identical protein binding	25416956.	IPI	Function

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

GWAS

PPI

Paralog

Ortholog

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.