EuRBPDB

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TCGA tumor abbreviations
  • ACCAdrenocortical carcinoma
  • BLCABladder Urothelial Carcinoma
  • BRCABreast invasive carcinoma
  • CESCCervical squamous cell carcinoma and endocervical adenocarcinoma
  • CHOLCholangio carcinoma
  • COADColon adenocarcinoma
  • DLBCLymphoid Neoplasm Diffuse Large B-cell Lymphoma
  • ESCAEsophageal carcinoma
  • GBMGlioblastoma multiforme
  • HNSCHead and Neck squamous cell carcinoma
  • KICHKidney Chromophobe
  • KIRCKidney renal clear cell carcinoma
  • KIRPKidney renal papillary cell carcinoma
  • LAMLAcute Myeloid Leukemia
  • LGGBrain Lower Grade Glioma
  • LIHCLiver hepatocellular carcinoma
  • LUADLung adenocarcinoma
  • LUSCLung squamous cell carcinoma
  • MESOMesothelioma
  • OVOvarian serous cystadenocarcinoma
  • PAADPancreatic adenocarcinoma
  • PCPGPheochromocytoma and Paraganglioma
  • PRADProstate adenocarcinoma
  • READRectum adenocarcinoma
  • SARCSarcoma
  • SKCMSkin Cutaneous Melanoma
  • STADStomach adenocarcinoma
  • TGCTThyroid carcinoma
  • THCAThyroid carcinoma
  • THYMThymoma
  • UCECUterine Corpus Endometrial Carcinoma
  • UCSUterine Carcinosarcoma
  • UVMUveal Melanoma

Note: Click here to get the extension of tumor abbreviations.


  • Cancer Related Information
  • Basic Information

Cancer associated literatures
PIDTitleArticle TimeAuthorDoi
26902425High TDP43 expression is required for TRIM16-induced inhibition of cancer cell growth and correlated with good prognosis of neuroblastoma and breast cancer patients.Cancer Lett2016 May 1Kim PYdoi: 10.1016/j.canlet.2016.02.021
26265046Regulation of MALAT1 expression by TDP43 controls the migration and invasion of non-small cell lung cancer cells invitro.Biochem Biophys Res Commun2015 Sep 18Guo Fdoi: 10.1016/j.bbrc.2015.08.027
29581274Loss of TDP43 inhibits progression of triple-negative breast cancer in coordination with SRSF3.Proc Natl Acad Sci U S A2018 Apr 10Ke Hdoi: 10.1073/pnas.1714573115

Expression in 33 cancers

Mutations
CancerChrPosition Mutation TypedbSNPProtein-change Allele FreqRBD
BLCAchr111016937Missense_MutationnovelL111R0.08RRM_1
BLCAchr111022629Missense_MutationNAS407C0.18
BLCAchr111018738SilentnovelK136K0.68
BLCAchr111016877Nonsense_MutationnovelS91*0.28RRM_1
BLCAchr111018743Missense_MutationNAD138A0.04
BRCAchr111022371Missense_MutationNAA321V0.23
CESCchr1110248323'UTRnovel0.11
CESCchr111013786Missense_MutationNAS20L0.24
CESCchr1110250073'UTRnovel0.38
CESCchr1110233783'UTRnovel0.56
CESCchr111018854Missense_MutationnovelC175Y0.25
CESCchr1110250003'UTRnovel0.15
COADchr1110232793'UTRnovel0.14
COADchr1110233703'UTRnovel0.47
COADchr111020527Silentrs138201492Y214Y0.38
COADchr111016918Missense_MutationNAD105N0.35RRM_1
COADchr111016918Missense_MutationNAD105N0.42RRM_1
COADchr111020527Silentrs138201492Y214Y0.31
COADchr111022586Missense_MutationnovelS393P0.31
COADchr111013751Silentrs72870030T8T0.41
ESCAchr1110253413'UTRnovel0.4
ESCAchr111020563SilentnovelF226F0.16
GBMchr111016939Missense_MutationnovelP112S0.07RRM_1
GBMchr1110227433'UTRnovel0.39
HNSCchr111020441Missense_MutationnovelE186Q0.13
HNSCchr111013716Splice_Regionnovel0.5
HNSCchr111016900Missense_MutationnovelA99T0.25RRM_1
HNSCchr111016969Missense_MutationnovelE122K0.2RRM_1
HNSCchr111018761Nonsense_MutationnovelS144*0.12
HNSCchr111022319Missense_MutationnovelG304S0.1
HNSCchr111020478Missense_MutationnovelC198Y0.21
HNSCchr111022148Missense_MutationnovelD247N0.1
LAMLchr111013898SilentnovelV57V0.21
LAMLchr1110226583'UTRnovel0.03
LAMLchr1110226593'UTRnovel0.03
LIHCchr1110229263'UTRnovel0.5
LIHCchr1110229773'UTRnovel0.52
LUADchr111022340Missense_MutationnovelM311L0.06
LUADchr111018796Missense_MutationNAE156K0.17
LUSCchr111020563Missense_MutationnovelF226L0.29
LUSCchr111013851Missense_MutationnovelR42C0.16
LUSCchr111016950SilentNAT115T0.17
LUSCchr1110227693'UTRnovel0.28
LUSCchr111022629Missense_MutationNAS407C0.07
OVchr111018788Missense_MutationNAT153M0.49
OVchr111013952SilentNAV75V0.29
OVchr111018799Missense_MutationNAT157A0.34
OVchr111022395Missense_MutationNAA329V0.14
OVchr111020474Frame_Shift_InsnovelR197Qfs*80.09
OVchr111020475Frame_Shift_InsnovelC198Lfs*100.08
OVchr111022207Frame_Shift_InsnovelN267*0.1
OVchr111022209Nonsense_MutationnovelN267_R268insCYS*LSF0.09
OVchr111022142Nonsense_MutationNAG245*0.34
PAADchr111022132SilentnovelQ241Q0.11
READchr111020576Missense_MutationnovelF231L0.12
READchr1110234613'UTRnovel0.17
READchr1110228343'UTRnovel0.39
SKCMchr111018856Nonsense_MutationnovelK176*0.11
SKCMchr111016877Missense_MutationNAS91L0.46RRM_1
SKCMchr111016994Missense_MutationnovelV130A0.13
SKCMchr111016944Missense_MutationnovelW113C0.28RRM_1
STADchr111013743Missense_MutationnovelR6W0.31
STADchr111022129Silentrs765175133A240A0.44
STADchr111022510Silentrs377531374F367F0.28
STADchr111022510Silentrs377531374F367F0.25
STADchr111013903Missense_MutationNAG59E0.24
STADchr111022587Missense_Mutationrs80356743S393L0.24
STADchr111016872SilentNAD89D0.19
STADchr111018817Missense_MutationNAS163P0.24
UCECchr111020476SilentnovelR197R0.09
UCECchr1110238063'UTRnovel0.39
UCECchr1110245073'UTRnovel0.39
UCECchr1110227423'UTRnovel0.45
UCECchr1110239883'UTRnovel0.57
UCECchr1110241003'UTRnovel0.55
UCECchr1110248983'UTRnovel0.34
UCECchr111016962Silentrs749962069D119D0.24
UCECchr1110249813'UTRnovel0.33
UCECchr111016916Missense_MutationnovelS104F0.44RRM_1
UCECchr1110236403'UTRnovel0.45
UCECchr111013717Splice_Regionnovel0.17
UCECchr111016954Missense_MutationNAE117K0.23RRM_1
UCECchr111020474Missense_MutationNAR197C0.38
UCECchr1110233503'UTRnovel0.49
UCECchr111022469Frame_Shift_InsnovelN355Kfs*180.45
UCECchr1110249633'UTRnovel0.48
UCECchr111016888Nonsense_MutationnovelK95*0.47RRM_1
UCECchr111016851SilentnovelK82K0.35
UCECchr1110234173'UTRnovel0.33
UCECchr1110250433'UTRnovel0.56
UCECchr111022560Frame_Shift_InsnovelW385Lfs*140.03
UCECchr1110231113'UTRnovel0.27
UCECchr111020475Missense_MutationnovelR197H0.47
UCECchr111022212Missense_MutationnovelR268I0.46
UCECchr111016954Missense_MutationNAE117K0.57RRM_1
UCECchr1110247393'UTRnovel0.29
UCECchr1110251053'UTRnovel0.16
UCECchr111016954Missense_MutationNAE117K0.39RRM_1
UCECchr111016887SilentnovelV94V0.28
UCECchr111016977Missense_MutationnovelF124L0.35
UCECchr1110250723'UTRnovel0.33
UCECchr1110252383'UTRnovel0.25
UCECchr1110227123'UTRnovel0.25
UCECchr1110232433'UTRnovel0.21
UCECchr1110244903'UTRnovel0.3
UCECchr1110252453'UTRnovel0.19
UCECchr1110236983'UTRnovel0.39
UCECchr1110230223'UTRnovel0.24
UCECchr1110137205'UTRnovel0.49
UCECchr1110232973'UTRnovel0.4
UCECchr1110246793'UTRnovel0.43
UCECchr1110226823'UTRnovel0.45
UCECchr111022371Missense_MutationNAA321G0.17
UCECchr111017008Splice_SitenovelX134_splice0.06
UCECchr1110240373'UTRnovel0.11
UCECchr111022128Missense_MutationNAA240V0.44
UCECchr111022596Frame_Shift_InsnovelF397Yfs*80.06
UCECchr111020527Silentrs138201492Y214Y0.25
UCECchr1110236223'UTRnovel0.28
UCECchr1110242163'UTRnovel0.46
UCECchr1110229803'UTRnovel0.35
UCECchr111022254Missense_MutationnovelG282D0.32
UCECchr1110227033'UTRnovel0.4
UCECchr1110233543'UTRnovel0.5
UCECchr1110229363'UTRnovel0.4

Copy Number Variations (CNVs)
CancerTypeFreq Q-value
CESCDEL0.10850.00029523
CHOLDEL0.77783.3987e-23
DLBCDEL0.10420.011841
HNSCDEL0.13987.0766e-07
KIRCDEL0.14392.3538e-09
KIRPDEL0.17361.462e-09
LUADDEL0.14340.0024765
LUSCDEL0.36532.5882e-07
MESODEL0.33332.434e-07
READDEL0.39392.1758e-10
TGCTDEL0.180.00046313
UCSDEL0.30360.0051125

Survival Analysis
CancerP-value Q-value
THYM0.0025

Kaplan-Meier Survival Analysis

SARC0.00017

Kaplan-Meier Survival Analysis

ACC0.00029

Kaplan-Meier Survival Analysis

UCS0.019

Kaplan-Meier Survival Analysis

SKCM0.02

Kaplan-Meier Survival Analysis

LUSC0.011

Kaplan-Meier Survival Analysis

BRCA0.014

Kaplan-Meier Survival Analysis

KIRP0.023

Kaplan-Meier Survival Analysis

BLCA0.031

Kaplan-Meier Survival Analysis

CESC0.0002

Kaplan-Meier Survival Analysis

READ0.045

Kaplan-Meier Survival Analysis

KICH0.0081

Kaplan-Meier Survival Analysis

UCEC0.037

Kaplan-Meier Survival Analysis

LIHC0.00011

Kaplan-Meier Survival Analysis

DLBC0.0066

Kaplan-Meier Survival Analysis

LGG0.00019

Kaplan-Meier Survival Analysis

OV0.027

Kaplan-Meier Survival Analysis

Drugs

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Eesembl ID



Cell lines and drugs in GSE70138 or GSE92742

  • Description
  • RBDs
  • RBPome
  • PRI
  • Literatures
  • Expression
  • Transcripts
  • Gene Model
  • GWAS
  • PPI
  • Paralogs
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000120948 (Gene tree)
Gene ID
23435
Gene Symbol
TARDBP
Alias
TDP-43|ALS10
Full Name
TAR DNA binding protein
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Plus strand
Length
14,077 bases
Position
chr1:11,012,344-11,026,420
Accession
11571
RBP type
canonical RBP
Summary
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]
RNA binding domains(RBDs)
Protein IDDomain Pfam IDE-value Domain number Total number
ENSP00000481206RRM_1PF00076.226.7e-2912
ENSP00000481206RRM_1PF00076.226.7e-2922
ENSP00000479219RRM_1PF00076.228.3e-2912
ENSP00000479219RRM_1PF00076.228.3e-2922
ENSP00000497327RRM_1PF00076.221.9e-2812
ENSP00000497327RRM_1PF00076.221.9e-2822
ENSP00000313129RRM_1PF00076.222.4e-2812
ENSP00000313129RRM_1PF00076.222.4e-2822
ENSP00000486989RRM_1PF00076.222.5e-2812
ENSP00000486989RRM_1PF00076.222.5e-2822
ENSP00000482191RRM_1PF00076.222.6e-2812
ENSP00000482191RRM_1PF00076.222.6e-2822
ENSP00000484722RRM_1PF00076.222.7e-2812
ENSP00000484722RRM_1PF00076.222.7e-2822
ENSP00000240185RRM_1PF00076.226.5e-2812
ENSP00000240185RRM_1PF00076.226.5e-2822
ENSP00000491203RRM_1PF00076.226.5e-2812
ENSP00000491203RRM_1PF00076.226.5e-2822
ENSP00000466842RRM_1PF00076.221e-2612
ENSP00000466842RRM_1PF00076.221e-2622
ENSP00000465240RRM_1PF00076.226.4e-1511
ENSP00000480690RRM_1PF00076.229.2e-1511
ENSP00000482559RRM_1PF00076.223.2e-1111
ENSP00000491085RRM_1PF00076.225.4e-0611
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
22681889The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts4SURIC & HEK2932012 MayBaltz AGDOI: 10.1016/j.molcel.2012.05.021
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
29431736Capturing the interactome of newly transcribed RNANascentRICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNAPolyT-RICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARIC & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
22658674Insights into RNA biology from an atlas of mammalian mRNA-binding proteinsRIC & Hela2012 May 31Castello ADOI: 10.1016/j.cell.2012.04.031
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & MCF72018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & U2OS2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
27453046Comprehensive Identification of RNA-Binding Domains in Human CellsRIC & Hela2016 Aug 18Castello ADOI: 10.1016/j.molcel.2016.06.029
30352994Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome captureRIC & Jurkat2018 Oct 23Perez-Perri JIDOI:10.1038/s41467-018-06557-8
Protein-RNA interaction(RNA-Binding Site)
Click here to download all RNA binding sites

Literatures on RNA binding capacity
PIDTitleArticle TimeAuthorDoi
28980860 behavior of proteins involved in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.Autophagy2017Uversky VNdoi: 10.1080/15548627.2017.1384889
27226551Developmentally Regulated RNA-binding Protein 1 (Drb1)/RNA-binding Motif Protein 45 (RBM45), a Nuclear-Cytoplasmic Trafficking Protein, Forms TAR DNA-binding Protein 43 (TDP-43)-mediated Cytoplasmic Aggregates.J Biol Chem2016 Jul 15Mashiko Tdoi: 10.1074/jbc.M115.712232
27033831Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis.Brain Res2016 Sep 15Shang Ydoi: 10.1016/j.brainres.2016.03.036
28090150M1 and M2 Functional Imprinting of Primary Microglia: Role of P2X7 Activation and miR-125b.Mediators Inflamm2016Parisi Cdoi: 10.1155/2016/2989548
23474849RNA dysfunction and aggrephagy at the centre of an amyotrophic lateral sclerosis/frontotemporal dementia disease continuum.Brain2013 MayThomas Mdoi: 10.1093/brain/awt030
26510133Transcriptomic Changes Due to Cytoplasmic TDP-43 Expression Reveal Dysregulation of Histone Transcripts and Nuclear Chromatin.PLoS One2015 Oct 28Amlie-Wolf Adoi: 10.1371/journal.pone.0141836
22028183RNA-binding proteins in neurodegenerative disease: TDP-43 and beyond.Wiley Interdiscip Rev RNA2012 Mar-AprHanson KAdoi: 10.1002/wrna.111
24113842TDP-43 regulates the microprocessor complex activity during in vitro neuronal differentiation.Mol Neurobiol2013 DecDi Carlo Vdoi: 10.1007/s12035-013-8564-x
23975767catRAPID omics: a web server for large-scale prediction of protein-RNA interactions.Bioinformatics2013 Nov 15Agostini Fdoi: 10.1093/bioinformatics/btt495
23804749RNA binding mediates neurotoxicity in the transgenic Drosophila model of TDP-43 proteinopathy.Hum Mol Genet2013 Nov 15Ihara Rdoi: 10.1093/hmg/ddt296
28167528Heat Shock-induced Phosphorylation of TAR DNA-binding Protein 43 (TDP-43) by MAPK/ERK Kinase Regulates TDP-43 Function.J Biol Chem2017 Mar 24Li Wdoi: 10.1074/jbc.M116.753913
26838063A molecular mechanism realizing sequence-specific recognition of nucleic acids by TDP-43.Sci Rep2016 Feb 3Furukawa Ydoi: 10.1038/srep20576.
26672899Analysis of RNA metabolism in peripheral WBCs of TDP-43 KI mice identifies novel biomarkers of ALS.Neurosci Res2016 MayHasegawa Mdoi: 10.1016/j.neures.2015.11.009
26525917MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis.Brain2016 JanMacNair Ldoi: 10.1093/brain/awv308
28600885Immunolocalization of TAR DNA-binding protein of 43kDa (TDP-43) in mouse seminiferous epithelium.Mol Reprod Dev2017 AugOsuru HPdoi: 10.1002/mrd.22851
31132467Cytoplasmic functions of TDP-43 and FUS and their role in ALS.Semin Cell Dev Biol2019 Jun 4Birsa Ndoi: 10.1016/j.semcdb.2019.05.023
31345270Mice deficient in the C-terminal domain of TAR DNA-binding protein 43 develop age-dependent motor dysfunction associated with impaired Notch1-Akt signaling pathway.Acta Neuropathol Commun2019 Jul 25Nishino Kdoi: 10.1186/s40478-019-0776-5.
17481916TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein.Mol Cell Neurosci2007 JunStrong MJ-
22079416Neurodegeneration the RNA way.Prog Neurobiol2012 MayRenoux AJdoi: 10.1016/j.pneurobio.2011.10.006
23280309RNA-mediated toxicity in neurodegenerative disease.Mol Cell Neurosci2013 SepBelzil VVdoi: 10.1016/j.mcn.2012.12.006
21358643Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.Nat Neurosci2011 AprPolymenidou Mdoi: 10.1038/nn.2779
20736350Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice.Proc Natl Acad Sci U S A2010 Sep 14Shan Xdoi: 10.1073/pnas.1003459107
20660762Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism.Proc Natl Acad Sci U S A2010 Sep 14Chiang PMdoi: 10.1073/pnas.1002176107
28072389Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106.Elife2017 Jan 10Celona Bdoi: 10.7554/eLife.19032.
26614389TDP-43 functions within a network of hnRNP proteins to inhibit the production of a truncated human SORT1 receptor.Hum Mol Genet2016 Feb 1Mohagheghi Fdoi: 10.1093/hmg/ddv491
26056265Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1.Proc Natl Acad Sci U S A2015 Jun 23Barmada SJdoi: 10.1073/pnas.1509744112
29916022Mechanisms Associated with TDP-43 Neurotoxicity in ALS/FTLD.Adv Neurobiol2018Shenouda Mdoi: 10.1007/978-3-319-89689-2_9.
22444279Misregulated RNA processing in amyotrophic lateral sclerosis.Brain Res2012 Jun 26Polymenidou Mdoi: 10.1016/j.brainres.2012.02.059
24507191Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations.Neuron2014 Feb 5Alami NHdoi: 10.1016/j.neuron.2013.12.018.
24464995The crystal structure of TDP-43 RRM1-DNA complex reveals the specific recognition for UG- and TG-rich nucleic acids.Nucleic Acids Res2014 AprKuo PHdoi: 10.1093/nar/gkt1407
27838743Intrinsic disorder in proteins involved in amyotrophic lateral sclerosis.Cell Mol Life Sci2017 AprSantamaria Ndoi: 10.1007/s00018-016-2416-6
18396105TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis.Lancet Neurol2008 MayVan Deerlin VMdoi: 10.1016/S1474-4422(08)70071-1
23118342Muscleblind, BSF and TBPH are mislocalized in the muscle sarcomere of a Drosophila myotonic dystrophy model.Dis Model Mech2013 JanLlamusi Bdoi: 10.1242/dmm.009563
23041957How do the RNA-binding proteins TDP-43 and FUS relate to amyotrophic lateral sclerosis and frontotemporal degeneration, and to each other?Curr Opin Neurol2012 DecBaloh RHdoi: 10.1097/WCO.0b013e32835a269b.
22934129Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain.Sci Rep2012Rogelj Bdoi: 10.1038/srep00603
22127299Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration.Nat Rev Neurosci2011 Nov 30Lee EBdoi: 10.1038/nrn3121.
21956718Conjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUS.Neurology2011 Oct 25Ito Ddoi: 10.1212/WNL.0b013e3182343365
21487023A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43.Hum Mol Genet2011 Jul 1Lanson NA Jrdoi: 10.1093/hmg/ddr150
21412718RNA-binding proteins and RNA metabolism: a new scenario in the pathogenesis of Amyotrophic lateral sclerosis.Arch Ital Biol2011 MarColombrita Cdoi: 10.4449/aib.v149i1.1261.
23172908Reduction of polyglutamine toxicity by TDP-43, FUS and progranulin in Huntington's disease models.Hum Mol Genet2013 Feb 15Tauffenberger Adoi: 10.1093/hmg/dds485
23196570[Conjoint pathological cascades mediated by RNA-binding proteins, TDP-43, FUS and ataxin-2].Rinsho Shinkeigaku2012Ito D-
20519548TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97.J Neurosci2010 Jun 2Ritson GPdoi: 10.1523/JNEUROSCI.5894-09.2010.
24920338TDP-43 suppresses CGG repeat-induced neurotoxicity through interactions with HnRNP A2/B1.Hum Mol Genet2014 Oct 1He Fdoi: 10.1093/hmg/ddu216
24799714Drosophila Valosin-Containing Protein is required for dendrite pruning through a regulatory role in mRNA metabolism.Proc Natl Acad Sci U S A2014 May 20Rumpf Sdoi: 10.1073/pnas.1406898111
24013423Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm.Cell Cycle2013 Oct 1Shelkovnikova TAdoi: 10.4161/cc.26241
23431168Reactive astrocytes secrete lcn2 to promote neuron death.Proc Natl Acad Sci U S A2013 Mar 5Bi Fdoi: 10.1073/pnas.1218497110
28265061Amyotrophic lateral sclerosis-linked mutations increase the viscosity of liquid-like TDP-43 RNP granules in neurons.Proc Natl Acad Sci U S A2017 Mar 21Gopal PPdoi: 10.1073/pnas.1614462114
27123980USP7 and TDP-43: Pleiotropic Regulation of Cryptochrome Protein Stability Paces the Oscillation of the Mammalian Circadian Clock.PLoS One2016 Apr 28Hirano Adoi: 10.1371/journal.pone.0154263
28301478Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS.PLoS Genet2017 Mar 16Krug Ldoi: 10.1371/journal.pgen.1006635
27368346Mislocated FUS is sufficient for gain-of-toxic-function amyotrophic lateral sclerosis phenotypes in mice.Brain2016 SepShiihashi Gdoi: 10.1093/brain/aww161
27015757Physiological functions and pathobiology of TDP-43 and FUS/TLS proteins.J Neurochem2016 AugRatti Adoi: 10.1111/jnc.13625
26735904ALS-Causing Mutations Significantly Perturb the Self-Assembly and Interaction with Nucleic Acid of the Intrinsically Disordered Prion-Like Domain of TDP-43.PLoS Biol2016 Jan 6Lim Ldoi: 10.1371/journal.pbio.1002338
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Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000315091TARDBP-2021835-ENSP00000313129295 (aa)-B1AKP7
ENST00000477447TARDBP-208409-ENSP0000046588865 (aa)-K7EL26
ENST00000639599TARDBP-2311283-ENSP00000492196295 (aa)-B1AKP7
ENST00000613864TARDBP-215584--- (aa)--
ENST00000619555TARDBP-221682-ENSP00000479978138 (aa)-A0A087WW61
ENST00000480464TARDBP-209790--- (aa)--
ENST00000473869TARDBP-2061946-ENSP00000432132298 (aa)-G3V162
ENST00000614494TARDBP-216515-ENSP0000048275478 (aa)-A0A087WZM1
ENST00000618606TARDBP-220584--- (aa)--
ENST00000639083TARDBP-2302269-ENSP00000491203414 (aa)-Q13148
ENST00000616545TARDBP-217920-ENSP00000484722301 (aa)-A0A087X260
ENST00000476201TARDBP-207929-ENSP00000466842275 (aa)-K7EN94
ENST00000473118TARDBP-205701-ENSP00000465240201 (aa)-K7EJM5
ENST00000638264TARDBP-229774-ENSP00000491085258 (aa)-A0A1W2PNU8
ENST00000496840TARDBP-210692-ENSP0000046702016 (aa)-K7ENM9
ENST00000617757TARDBP-219434--- (aa)--
ENST00000610369TARDBP-211563-ENSP00000482559127 (aa)-A0A087WZC9
ENST00000439080TARDBP-2031388-ENSP0000040466684 (aa)-A0A0A0MSV7
ENST00000622057TARDBP-227706-ENSP00000481206200 (aa)-A0A087WXQ5
ENST00000240185TARDBP-2015367XM_017000863ENSP00000240185414 (aa)XP_016856352Q13148
ENST00000620632TARDBP-223706-ENSP00000480771149 (aa)-A0A087WX67
ENST00000621790TARDBP-2261008-ENSP00000482191304 (aa)-A0A087WYY0
ENST00000611008TARDBP-212929--- (aa)--
ENST00000649624TARDBP-232810-ENSP00000497327269 (aa)-A0A0A0N0M3
ENST00000613177TARDBP-214379--- (aa)--
ENST00000620505TARDBP-222657-ENSP00000479758115 (aa)-A0A087WVX6
ENST00000629725TARDBP-2281031-ENSP00000486989298 (aa)-G3V162
ENST00000472476TARDBP-2041001-ENSP0000046508080 (aa)-K7EJ99
ENST00000611963TARDBP-213739-ENSP00000481330175 (aa)-A0A087WXV3
ENST00000621715TARDBP-225816-ENSP00000480690243 (aa)-A0A087WX29
ENST00000617172TARDBP-218980-ENSP00000479219212 (aa)-A0A087WV68
ENST00000621573TARDBP-224992-ENSP0000047785235 (aa)-A0A087WTG4
Gene Model
Click here to download ENSG00000120948's gene model file
GWAS
ensgIDSNPChromosomePositionSNP-risk TraitPubmedID95% CIOr or BEAT EFO ID
ENSG00000120948rs34247753111014942CMale-pattern baldness28196072NR unit increase0.0482657Orphanet_79364
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000120948's network

* RBP PPI network refers to all genes directly bind to RBP
Paralogs
Ensembl IDGene SymbolCoverageIdentiy ParalogGene SymbolCoverageIdentiy
ENSG00000120948TARDBP7738.194ENSG00000138668HNRNPD9943.363
ENSG00000120948TARDBP7730.556ENSG00000066044ELAVL15930.556
ENSG00000120948TARDBP8034.921ENSG00000170144HNRNPA39130.699
ENSG00000120948TARDBP9231.507ENSG00000153944MSI28831.507
ENSG00000120948TARDBP7732.075ENSG00000152795HNRNPDL6134.746
ENSG00000120948TARDBP8531.073ENSG00000197451HNRNPAB7530.275
ENSG00000120948TARDBP6342.593ENSG00000135486HNRNPA19637.615
ENSG00000120948TARDBP9130.208ENSG00000122566HNRNPA2B17732.886
ENSG00000120948TARDBP5331.579ENSG00000107105ELAVL28831.579
ENSG00000120948TARDBP9432.184ENSG00000071626DAZAP15533.862
ENSG00000120948TARDBP8232.026ENSG00000139675HNRNPA1L26032.812
Orthologs
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000120948TARDBP9986.250ENSAPOG00000012879tardbpl9780.277Acanthochromis_polyacanthus
ENSG00000120948TARDBP9986.869ENSAPOG00000002526tardbp9973.301Acanthochromis_polyacanthus
ENSG00000120948TARDBP10099.005ENSAMEG00000009476TARDBP10097.585Ailuropoda_melanoleuca
ENSG00000120948TARDBP10070.149ENSAMEG00000008772-10069.888Ailuropoda_melanoleuca
ENSG00000120948TARDBP9986.869ENSACIG00000009109tardbp9972.816Amphilophus_citrinellus
ENSG00000120948TARDBP10082.673ENSACIG00000003327tardbpl10069.431Amphilophus_citrinellus
ENSG00000120948TARDBP9986.250ENSAOCG00000020211tardbpl9779.931Amphiprion_ocellaris
ENSG00000120948TARDBP9986.869ENSAOCG00000002631tardbp9972.816Amphiprion_ocellaris
ENSG00000120948TARDBP9986.250ENSAPEG00000018093tardbpl9779.931Amphiprion_percula
ENSG00000120948TARDBP9986.869ENSAPEG00000002615tardbp9972.816Amphiprion_percula
ENSG00000120948TARDBP10084.653ENSATEG00000017658tardbpl9879.110Anabas_testudineus
ENSG00000120948TARDBP9986.869ENSATEG00000024840tardbp9972.816Anabas_testudineus
ENSG00000120948TARDBP9998.734ENSAPLG00000006001TARDBP10094.928Anas_platyrhynchos
ENSG00000120948TARDBP9681.347ENSANAG00000027281-9984.878Aotus_nancymaae
ENSG00000120948TARDBP10099.005ENSANAG00000035249-10098.792Aotus_nancymaae
ENSG00000120948TARDBP9986.869ENSACLG00000013961tardbp9972.816Astatotilapia_calliptera
ENSG00000120948TARDBP10081.683ENSACLG00000025494tardbpl9777.509Astatotilapia_calliptera
ENSG00000120948TARDBP9987.500ENSAMXG00000030795tardbpl9580.623Astyanax_mexicanus
ENSG00000120948TARDBP9985.000ENSAMXG00000039549tardbp9969.305Astyanax_mexicanus
ENSG00000120948TARDBP99100.000ENSBTAG00000003697TARDBP10097.585Bos_taurus
ENSG00000120948TARDBP9939.823WBGene00006514tdp-17338.816Caenorhabditis_elegans
ENSG00000120948TARDBP10099.005ENSCJAG00000002381TARDBP10098.792Callithrix_jacchus
ENSG00000120948TARDBP10099.005ENSCAFG00000016759TARDBP10097.826Canis_familiaris
ENSG00000120948TARDBP10099.005ENSCAFG00020002258-10097.826Canis_lupus_dingo
ENSG00000120948TARDBP97100.000ENSCAFG00020013548-10076.952Canis_lupus_dingo
ENSG00000120948TARDBP99100.000ENSCHIG00000026090TARDBP10097.585Capra_hircus
ENSG00000120948TARDBP99100.000ENSTSYG00000004077TARDBP10097.101Carlito_syrichta
ENSG00000120948TARDBP10099.005ENSCAPG00000015189TARDBP10097.585Cavia_aperea
ENSG00000120948TARDBP10099.005ENSCPOG00000011619TARDBP10097.585Cavia_porcellus
ENSG00000120948TARDBP10099.005ENSCCAG00000025859-10098.792Cebus_capucinus
ENSG00000120948TARDBP9788.235ENSCCAG00000034419-9779.184Cebus_capucinus
ENSG00000120948TARDBP9996.491ENSCCAG00000010279-10085.956Cebus_capucinus
ENSG00000120948TARDBP9797.059ENSCATG00000029126-10072.705Cercocebus_atys
ENSG00000120948TARDBP99100.000ENSCATG00000031367TARDBP10095.894Cercocebus_atys
ENSG00000120948TARDBP10099.005ENSCLAG00000014547TARDBP10097.368Chinchilla_lanigera
ENSG00000120948TARDBP10099.517ENSCSAG00000019136-10099.517Chlorocebus_sabaeus
ENSG00000120948TARDBP100100.000ENSCSAG00000000785-10099.758Chlorocebus_sabaeus
ENSG00000120948TARDBP99100.000ENSCHOG00000013276-9880.165Choloepus_hoffmanni
ENSG00000120948TARDBP10099.005ENSCPBG00000022012TARDBP10096.135Chrysemys_picta_bellii
ENSG00000120948TARDBP9559.459ENSCING00000000050tardbp6257.091Ciona_intestinalis
ENSG00000120948TARDBP9753.947ENSCSAVG00000008831-6555.088Ciona_savignyi
ENSG00000120948TARDBP100100.000ENSCANG00000030022TARDBP100100.000Colobus_angolensis_palliatus
ENSG00000120948TARDBP9977.889ENSCANG00000023420-9166.586Colobus_angolensis_palliatus
ENSG00000120948TARDBP9993.671ENSCGRG00001015454-10068.116Cricetulus_griseus_chok1gshd
ENSG00000120948TARDBP10099.005ENSCGRG00001010684-10096.382Cricetulus_griseus_chok1gshd
ENSG00000120948TARDBP10099.005ENSCGRG00000007923-10096.309Cricetulus_griseus_crigri
ENSG00000120948TARDBP9993.671ENSCGRG00000002018-10068.116Cricetulus_griseus_crigri
ENSG00000120948TARDBP9985.000ENSCSEG00000005274tardbpl9380.427Cynoglossus_semilaevis
ENSG00000120948TARDBP9983.838ENSCSEG00000021744tardbp9969.417Cynoglossus_semilaevis
ENSG00000120948TARDBP9986.364ENSCVAG00000006178tardbp9974.515Cyprinodon_variegatus
ENSG00000120948TARDBP9986.250ENSCVAG00000016647tardbpl9880.623Cyprinodon_variegatus
ENSG00000120948TARDBP9985.000ENSDARG00000040031tardbp9969.585Danio_rerio
ENSG00000120948TARDBP9986.364ENSDARG00000004452tardbpl9581.164Danio_rerio
ENSG00000120948TARDBP10098.507ENSDNOG00000008531TARDBP10096.860Dasypus_novemcinctus
ENSG00000120948TARDBP99100.000ENSDORG00000007465Tardbp10096.618Dipodomys_ordii
ENSG00000120948TARDBP8673.134FBgn0025790TBPH8657.093Drosophila_melanogaster
ENSG00000120948TARDBP8767.647FBgn0036496CG78048454.074Drosophila_melanogaster
ENSG00000120948TARDBP9996.491ENSETEG00000004358TARDBP10096.108Echinops_telfairi
ENSG00000120948TARDBP9564.865ENSEBUG00000000353-8445.625Eptatretus_burgeri
ENSG00000120948TARDBP9781.250ENSEBUG00000015638tardbpl8458.099Eptatretus_burgeri
ENSG00000120948TARDBP9465.753ENSEBUG00000007562-8856.098Eptatretus_burgeri
ENSG00000120948TARDBP10099.005ENSEASG00005019017TARDBP10097.585Equus_asinus_asinus
ENSG00000120948TARDBP10099.005ENSECAG00000008338TARDBP10097.585Equus_caballus
ENSG00000120948TARDBP9999.123ENSEEUG00000003755TARDBP10097.101Erinaceus_europaeus
ENSG00000120948TARDBP9986.869ENSELUG00000009090tardbp9972.573Esox_lucius
ENSG00000120948TARDBP9987.500ENSELUG00000013252tardbpl9579.110Esox_lucius
ENSG00000120948TARDBP9281.944ENSFCAG00000040067-9783.237Felis_catus
ENSG00000120948TARDBP10099.005ENSFCAG00000000050TARDBP10097.585Felis_catus
ENSG00000120948TARDBP10098.010ENSFALG00000007199TARDBP9993.961Ficedula_albicollis
ENSG00000120948TARDBP10099.005ENSFDAG00000004675TARDBP10097.585Fukomys_damarensis
ENSG00000120948TARDBP9986.364ENSFHEG00000019998tardbp9972.816Fundulus_heteroclitus
ENSG00000120948TARDBP9986.250ENSFHEG00000010145tardbpl9780.623Fundulus_heteroclitus
ENSG00000120948TARDBP10085.185ENSGMOG00000016367tardbp9969.617Gadus_morhua
ENSG00000120948TARDBP9986.250ENSGMOG00000000526tardbpl9184.133Gadus_morhua
ENSG00000120948TARDBP10098.010ENSGALG00000002906TARDBP10095.411Gallus_gallus
ENSG00000120948TARDBP9986.250ENSGAFG00000019234tardbpl10069.596Gambusia_affinis
ENSG00000120948TARDBP9986.364ENSGAFG00000011052tardbp9972.816Gambusia_affinis
ENSG00000120948TARDBP9985.354ENSGACG00000012164tardbp9973.544Gasterosteus_aculeatus
ENSG00000120948TARDBP10084.653ENSGACG00000007124tardbpl9780.277Gasterosteus_aculeatus
ENSG00000120948TARDBP10099.005ENSGAGG00000009283TARDBP10095.894Gopherus_agassizii
ENSG00000120948TARDBP9782.895ENSGGOG00000042352-10063.123Gorilla_gorilla
ENSG00000120948TARDBP97100.000ENSGGOG00000028580-10073.864Gorilla_gorilla
ENSG00000120948TARDBP99100.000ENSGGOG00000015357-82100.000Gorilla_gorilla
ENSG00000120948TARDBP9986.869ENSHBUG00000002328tardbp9972.816Haplochromis_burtoni
ENSG00000120948TARDBP10081.683ENSHBUG00000020551tardbpl9777.509Haplochromis_burtoni
ENSG00000120948TARDBP9981.013ENSHGLG00000008540-10087.970Heterocephalus_glaber_female
ENSG00000120948TARDBP10098.507ENSHGLG00000018967TARDBP10097.585Heterocephalus_glaber_female
ENSG00000120948TARDBP10098.507ENSHGLG00100014781TARDBP10097.585Heterocephalus_glaber_male
ENSG00000120948TARDBP10087.562ENSHGLG00100006769-10086.715Heterocephalus_glaber_male
ENSG00000120948TARDBP10085.644ENSHCOG00000015858tardbpl9980.969Hippocampus_comes
ENSG00000120948TARDBP9589.189ENSHCOG00000002224tardbp9971.325Hippocampus_comes
ENSG00000120948TARDBP9985.222ENSIPUG00000004992tardbp9580.969Ictalurus_punctatus
ENSG00000120948TARDBP9983.085ENSIPUG00000023818TARDBP9968.675Ictalurus_punctatus
ENSG00000120948TARDBP10098.507ENSSTOG00000008406-10097.101Ictidomys_tridecemlineatus
ENSG00000120948TARDBP9999.123ENSSTOG00000021089-10092.271Ictidomys_tridecemlineatus
ENSG00000120948TARDBP99100.000ENSJJAG00000014196-10095.932Jaculus_jaculus
ENSG00000120948TARDBP10084.158ENSKMAG00000015796tardbpl9779.585Kryptolebias_marmoratus
ENSG00000120948TARDBP9986.869ENSKMAG00000005913tardbp8673.301Kryptolebias_marmoratus
ENSG00000120948TARDBP9986.364ENSLBEG00000022827tardbp9781.695Labrus_bergylta
ENSG00000120948TARDBP9985.000ENSLBEG00000021801tardbpl9878.498Labrus_bergylta
ENSG00000120948TARDBP10090.547ENSLACG00000017101TARDBP10081.687Latimeria_chalumnae
ENSG00000120948TARDBP9990.909ENSLOCG00000006604tardbpl9978.935Lepisosteus_oculatus
ENSG00000120948TARDBP10099.005ENSLAFG00000014421TARDBP10097.585Loxodonta_africana
ENSG00000120948TARDBP9984.810ENSMFAG00000000832-10084.772Macaca_fascicularis
ENSG00000120948TARDBP100100.000ENSMFAG00000002750TARDBP100100.000Macaca_fascicularis
ENSG00000120948TARDBP100100.000ENSMMUG00000007456TARDBP100100.000Macaca_mulatta
ENSG00000120948TARDBP10084.080ENSMMUG00000003940-9982.353Macaca_mulatta
ENSG00000120948TARDBP9990.351ENSMNEG00000025649-10076.570Macaca_nemestrina
ENSG00000120948TARDBP100100.000ENSMNEG00000030163TARDBP100100.000Macaca_nemestrina
ENSG00000120948TARDBP10099.661ENSMLEG00000041791TARDBP10099.661Mandrillus_leucophaeus
ENSG00000120948TARDBP9986.250ENSMAMG00000009233tardbpl9778.893Mastacembelus_armatus
ENSG00000120948TARDBP9986.869ENSMAMG00000016626tardbp9972.816Mastacembelus_armatus
ENSG00000120948TARDBP9986.869ENSMZEG00005014992tardbp9972.816Maylandia_zebra
ENSG00000120948TARDBP10081.683ENSMZEG00005013608tardbpl9777.509Maylandia_zebra
ENSG00000120948TARDBP10098.010ENSMGAG00000004637TARDBP10095.411Meleagris_gallopavo
ENSG00000120948TARDBP99100.000ENSMAUG00000018057Tardbp10095.973Mesocricetus_auratus
ENSG00000120948TARDBP99100.000ENSMICG00000003838TARDBP10095.652Microcebus_murinus
ENSG00000120948TARDBP10099.005ENSMOCG00000003562Tardbp10096.309Microtus_ochrogaster
ENSG00000120948TARDBP9986.364ENSMMOG00000011034tardbp9972.816Mola_mola
ENSG00000120948TARDBP9985.000ENSMMOG00000009189tardbpl10070.024Mola_mola
ENSG00000120948TARDBP10099.005ENSMODG00000011233-10097.315Monodelphis_domestica
ENSG00000120948TARDBP9983.544ENSMODG00000000892-10073.966Monodelphis_domestica
ENSG00000120948TARDBP9987.374ENSMALG00000001764tardbp9973.058Monopterus_albus
ENSG00000120948TARDBP10084.158ENSMALG00000021161tardbpl9778.893Monopterus_albus
ENSG00000120948TARDBP10099.177MGP_CAROLIEiJ_G0026805Tardbp10099.329Mus_caroli
ENSG00000120948TARDBP10099.177ENSMUSG00000041459Tardbp10099.329Mus_musculus
ENSG00000120948TARDBP99100.000MGP_PahariEiJ_G0029153Tardbp10098.765Mus_pahari
ENSG00000120948TARDBP10099.177MGP_SPRETEiJ_G0027798Tardbp10099.329Mus_spretus
ENSG00000120948TARDBP10099.005ENSMPUG00000016443TARDBP10097.315Mustela_putorius_furo
ENSG00000120948TARDBP10099.005ENSMLUG00000004263TARDBP10097.101Myotis_lucifugus
ENSG00000120948TARDBP10077.114ENSNGAG00000011442-9773.219Nannospalax_galili
ENSG00000120948TARDBP10099.005ENSNGAG00000023416-10097.288Nannospalax_galili
ENSG00000120948TARDBP10081.683ENSNBRG00000006706tardbpl9777.509Neolamprologus_brichardi
ENSG00000120948TARDBP9985.572ENSNBRG00000019066tardbp9972.289Neolamprologus_brichardi
ENSG00000120948TARDBP9697.333ENSNLEG00000026620-9294.574Nomascus_leucogenys
ENSG00000120948TARDBP9994.937ENSNLEG00000027732-9072.890Nomascus_leucogenys
ENSG00000120948TARDBP100100.000ENSNLEG00000009512TARDBP100100.000Nomascus_leucogenys
ENSG00000120948TARDBP10099.005ENSMEUG00000006548TARDBP10097.368Notamacropus_eugenii
ENSG00000120948TARDBP10097.512ENSOPRG00000006352TARDBP10096.860Ochotona_princeps
ENSG00000120948TARDBP9991.139ENSODEG00000002855-10070.433Octodon_degus
ENSG00000120948TARDBP9977.215ENSODEG00000006114-9566.496Octodon_degus
ENSG00000120948TARDBP99100.000ENSODEG00000013739-100100.000Octodon_degus
ENSG00000120948TARDBP10082.178ENSONIG00000002332tardbpl9777.855Oreochromis_niloticus
ENSG00000120948TARDBP9984.729ENSONIG00000004027tardbp9971.942Oreochromis_niloticus
ENSG00000120948TARDBP10099.005ENSOANG00000013320TARDBP10097.585Ornithorhynchus_anatinus
ENSG00000120948TARDBP9290.278ENSOCUG00000004049-10090.521Oryctolagus_cuniculus
ENSG00000120948TARDBP9986.869ENSORLG00000003593tardbp9973.301Oryzias_latipes
ENSG00000120948TARDBP9986.250ENSORLG00000005188tardbpl9780.690Oryzias_latipes
ENSG00000120948TARDBP9986.869ENSORLG00020021206tardbp9973.544Oryzias_latipes_hni
ENSG00000120948TARDBP9986.250ENSORLG00020013159tardbpl9780.690Oryzias_latipes_hni
ENSG00000120948TARDBP9986.869ENSORLG00015017343tardbp9972.816Oryzias_latipes_hsok
ENSG00000120948TARDBP9986.250ENSORLG00015005048tardbpl9780.690Oryzias_latipes_hsok
ENSG00000120948TARDBP9986.869ENSOMEG00000000997tardbp9973.058Oryzias_melastigma
ENSG00000120948TARDBP9986.250ENSOMEG00000003102tardbpl9780.345Oryzias_melastigma
ENSG00000120948TARDBP99100.000ENSOGAG00000016721TARDBP10087.500Otolemur_garnettii
ENSG00000120948TARDBP9474.615ENSOARG00000020974-10066.522Ovis_aries
ENSG00000120948TARDBP9998.246ENSOARG00000010657-10096.418Ovis_aries
ENSG00000120948TARDBP99100.000ENSOARG00000004268-10096.386Ovis_aries
ENSG00000120948TARDBP97100.000ENSPPAG00000024941-10076.154Pan_paniscus
ENSG00000120948TARDBP100100.000ENSPPAG00000039086TARDBP100100.000Pan_paniscus
ENSG00000120948TARDBP10099.005ENSPPRG00000003255TARDBP10097.585Panthera_pardus
ENSG00000120948TARDBP10080.100ENSPTIG00000014945-9976.042Panthera_tigris_altaica