EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
11687974	A novel nuclear protein, 5qNCA (LOC51780) is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31.	Oncogene	2001 Oct 18	Hu Z	-
28540746	KDM3B shows tumor-suppressive activity and transcriptionally regulates HOXA1 through retinoic acid response elements in acute myeloid leukemia.	Leuk Lymphoma	2018 Jan	Xu X	doi: 10.1080/10428194.2017.1324156
23266085	Histone lysine demethylases in breast cancer.	Crit Rev Oncol Hematol	2013 May	Paolicchi E	doi: 10.1016/j.critrevonc.2012.11.008

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr5	138386579	Silent	novel	V446V	0.45
BLCA	chr5	138415140	Missense_Mutation	novel	E1070Q	0.36
BLCA	chr5	138419132	Silent	novel	L1205L	0.32
BLCA	chr5	138420739	Missense_Mutation	NA	E1250G	0.13
BLCA	chr5	138417582	Missense_Mutation	novel	R1136K	0.09
BLCA	chr5	138386335	Frame_Shift_Del	novel	*R365Tfs6**	0.45
BLCA	chr5	138430390	Missense_Mutation	novel	D1679N	0.27
BLCA	chr5	138424135	Missense_Mutation	novel	E1345K	0.47
BLCA	chr5	138391214	Missense_Mutation	novel	Q528K	0.27
BLCA	chr5	138377809	Silent	novel	Q188Q	0.11
BLCA	chr5	138391404	Missense_Mutation	rs374559198	R591Q	0.16
BLCA	chr5	138435664	Silent	novel	T1750T	0.16
BLCA	chr5	138415134	Missense_Mutation	NA	T1068A	0.24
BLCA	chr5	138381582	Nonsense_Mutation	novel	Q258*	0.55
BLCA	chr5	138427991	Missense_Mutation	novel	R1553K	0.42
BLCA	chr5	138386066	Frame_Shift_Ins	novel	*R276Kfs21**	0.1
BLCA	chr5	138420794	Silent	rs751194137	P1268P	0.14
BLCA	chr5	138431458	Missense_Mutation	novel	E1702K	0.32
BLCA	chr5	138427238	Missense_Mutation	novel	D1518N	0.05
BLCA	chr5	138428026	Missense_Mutation	NA	D1565H	0.19
BLCA	chr5	138425553	Missense_Mutation	NA	D1461G	0.52
BLCA	chr5	138391664	Missense_Mutation	novel	H678Y	0.35
BLCA	chr5	138425517	Missense_Mutation	NA	R1449M	0.22
BLCA	chr5	138399959	Missense_Mutation	NA	G1049E	0.18
BLCA	chr5	138386355	Nonsense_Mutation	novel	E372*	0.83
BRCA	chr5	138424200	Silent	rs771965473	V1366V	0.22
BRCA	chr5	138430331	Missense_Mutation	NA	R1659H	0.21
BRCA	chr5	138386193	Missense_Mutation	NA	E318K	0.22
BRCA	chr5	138392257	Silent	novel	L875L	0.29
BRCA	chr5	138386430	Missense_Mutation	NA	E397Q	0.19
BRCA	chr5	138424083	Missense_Mutation	NA	K1327N	0.35
BRCA	chr5	138391662	Missense_Mutation	novel	S677C	0.2
BRCA	chr5	138386301	Missense_Mutation	NA	I354F	0.14
BRCA	chr5	138386254	Missense_Mutation	NA	R338T	0.3
BRCA	chr5	138435764	3'UTR	novel		0.19
BRCA	chr5	138424250	Missense_Mutation	novel	S1383Y	0.22
BRCA	chr5	138435671	Missense_Mutation	rs760813802	A1753T	0.23
BRCA	chr5	138391769	Frame_Shift_Del	NA	*G714Afs81**	0.22
BRCA	chr5	138425537	Missense_Mutation	rs745528581	D1456N	0.11
CESC	chr5	138435667	Silent	novel	L1751L	0.06
CESC	chr5	138419208	Nonsense_Mutation	NA	Q1231*	0.25
CESC	chr5	138428040	Silent	NA	V1569V	0.19
CESC	chr5	138426974	Splice_Site	NA	X1471_splice	0.37
CESC	chr5	138427201	Silent	NA	L1505L	0.44
CESC	chr5	138391976	Missense_Mutation	NA	D782N	0.46
CESC	chr5	138399859	Splice_Site	novel	X1016_splice	0.23
CESC	chr5	138386021	Splice_Site	novel	X262_splice	0.43
CESC	chr5	138424314	Silent	NA	I1404I	0.31
CESC	chr5	138429960	Nonsense_Mutation	NA	R1630*	0.25
CESC	chr5	138435654	Missense_Mutation	NA	A1747V	0.29
CESC	chr5	138420788	Silent	novel	V1266V	0.1
CESC	chr5	138391668	Missense_Mutation	novel	S679C	0.41
CESC	chr5	138391785	Missense_Mutation	rs754696681	S718C	0.38
CESC	chr5	138391918	Silent	NA	L762L	0.36
CESC	chr5	138391961	Missense_Mutation	NA	L777V	0.37
CESC	chr5	138392088	Nonsense_Mutation	NA	S819*	0.41
CESC	chr5	138392061	Missense_Mutation	novel	S810L	0.13
COAD	chr5	138399931	Missense_Mutation	NA	N1040D	0.17
COAD	chr5	138420901	Missense_Mutation	NA	L1304H	0.24
COAD	chr5	138377777	Missense_Mutation	NA	V178F	0.33
COAD	chr5	138391077	Missense_Mutation	NA	P482H	0.38
COAD	chr5	138391421	Missense_Mutation	NA	S597T	0.42
COAD	chr5	138420919	Missense_Mutation	NA	D1310G	0.47
COAD	chr5	138429880	Missense_Mutation	NA	I1603S	0.2
COAD	chr5	138391505	Frame_Shift_Del	NA	*K627Nfs60**	0.38
COAD	chr5	138391121	Missense_Mutation	NA	A497T	0.42
COAD	chr5	138381532	Missense_Mutation	novel	S241L	0.3
COAD	chr5	138391954	Silent	rs140375150	G774G	0.38
COAD	chr5	138420960	Missense_Mutation	novel	A1324P	0.25
COAD	chr5	138392036	Nonsense_Mutation	novel	R802*	0.27
COAD	chr5	138417560	Nonsense_Mutation	novel	R1129*	0.33
COAD	chr5	138398393	Splice_Site	NA	X1016_splice	0.18
COAD	chr5	138386094	Missense_Mutation	NA	R285W	0.18
COAD	chr5	138381588	Missense_Mutation	NA	E260K	0.27
COAD	chr5	138427312	Silent	rs368913432	N1542N	0.21
COAD	chr5	138400006	Missense_Mutation	rs539384678	R1065C	0.35
COAD	chr5	138427236	Missense_Mutation	novel	R1517Q	0.21
COAD	chr5	138377822	Nonsense_Mutation	NA	R193*	0.35
COAD	chr5	138393230	Missense_Mutation	novel	P897S	0.13
COAD	chr5	138386202	Nonsense_Mutation	NA	R321*	0.19
COAD	chr5	138391079	Missense_Mutation	NA	L483V	0.15
COAD	chr5	138430333	Missense_Mutation	novel	K1660E	0.04
COAD	chr5	138391186	Missense_Mutation	NA	D518E	0.08
COAD	chr5	138424314	Silent	NA	I1404I	0.1
COAD	chr5	138435772	3'UTR	novel		0.32
COAD	chr5	138420936	Frame_Shift_Del	NA	*P1317Rfs10**	0.45
COAD	chr5	138393358	Missense_Mutation	NA	F939L	0.36
COAD	chr5	138425569	Silent	rs762393674	F1466F	0.2
ESCA	chr5	138425550	Missense_Mutation	rs529065296	R1460Q	0.2
ESCA	chr5	138424254	Missense_Mutation	novel	W1384C	0.41
ESCA	chr5	138391698	Missense_Mutation	novel	K689T	0.22
ESCA	chr5	138391799	Missense_Mutation	novel	G723S	0.7
ESCA	chr5	138417564	Missense_Mutation	novel	Q1130L	0.17
GBM	chr5	138391597	Missense_Mutation	novel	Q655H	0.09
GBM	chr5	138372694	Silent	novel	G71G	0.07
GBM	chr5	138391836	Missense_Mutation	novel	P735R	0.04
GBM	chr5	138386202	Nonsense_Mutation	NA	R321*	0.05
GBM	chr5	138392015	Nonsense_Mutation	novel	K795*	0.18
GBM	chr5	138424186	Missense_Mutation	novel	T1362A	0.06
GBM	chr5	138377771	Missense_Mutation	novel	E176K	0.04
GBM	chr5	138377720	Missense_Mutation	novel	M159L	0.06
GBM	chr5	138392217	Missense_Mutation	novel	G862A	0.05
GBM	chr5	138391071	Missense_Mutation	novel	S480L	0.05
GBM	chr5	138425537	Missense_Mutation	rs745528581	D1456N	0.2
GBM	chr5	138424225	Missense_Mutation	novel	V1375L	0.1
GBM	chr5	138430397	Missense_Mutation	novel	V1681A	0.06
GBM	chr5	138393307	Silent	novel	Y922Y	0.27
GBM	chr5	138425430	Missense_Mutation	novel	V1420E	0.17
GBM	chr5	138393322	Silent	novel	E927E	0.08
GBM	chr5	138393284	Frame_Shift_Del	novel	*R915Vfs21**	0.06
GBM	chr5	138391863	Missense_Mutation	novel	S744I	0.11
GBM	chr5	138399873	Nonsense_Mutation	novel	W1020*	0.08
HNSC	chr5	138379698	Missense_Mutation	novel	S232F	0.15
HNSC	chr5	138391405	Frame_Shift_Del	novel	*K592Cfs18**	0.2
HNSC	chr5	138426977	Nonsense_Mutation	NA	R1472*	0.2
HNSC	chr5	138393309	Frame_Shift_Del	novel	*K924Sfs12**	0.32
HNSC	chr5	138392027	Silent	novel	L799L	0.13
HNSC	chr5	138417608	Missense_Mutation	novel	Q1145K	0.2
HNSC	chr5	138419132	Silent	novel	L1205L	0.32
HNSC	chr5	138430331	Missense_Mutation	NA	R1659H	0.17
HNSC	chr5	138391491	Missense_Mutation	novel	N620S	0.1
HNSC	chr5	138399916	Missense_Mutation	novel	E1035K	0.25
KIRC	chr5	138377818	Silent	rs770604921	F191F	0.27
KIRC	chr5	138425443	Silent	NA	L1424L	0.08
KIRC	chr5	138372831	Missense_Mutation	NA	W117L	0.21
KIRC	chr5	138435710	3'UTR	novel		0.17
KIRC	chr5	138435741	3'UTR	novel		0.59
KIRP	chr5	138379684	Silent	NA	R227R	0.36
KIRP	chr5	138393231	Missense_Mutation	novel	P897L	0.53
KIRP	chr5	138381568	Missense_Mutation	NA	D253A	0.35
KIRP	chr5	138430343	Missense_Mutation	NA	Y1663C	0.15
KIRP	chr5	138391274	Missense_Mutation	novel	A548T	0.42
KIRP	chr5	138424336	Missense_Mutation	novel	G1412R	0.24
LAML	chr5	138393354	Missense_Mutation	NA	R938H	0.79
LAML	chr5	138392111	Frame_Shift_Del	NA	*Q827Sfs8**	0.67
LGG	chr5	138372750	Missense_Mutation	NA	L90H	0.38
LGG	chr5	138381527	Silent	NA	I239I	0.25
LGG	chr5	138386114	Silent	novel	S291S	0.36
LGG	chr5	138386271	Missense_Mutation	novel	S344T	0.11
LIHC	chr5	138424264	Missense_Mutation	NA	G1388W	0.29
LIHC	chr5	138424265	Missense_Mutation	novel	G1388V	0.28
LIHC	chr5	138427285	Missense_Mutation	novel	R1533S	0.69
LIHC	chr5	138398310	Silent	novel	K988K	0.13
LIHC	chr5	138417510	Missense_Mutation	novel	H1112L	0.05
LIHC	chr5	138419133	Nonsense_Mutation	novel	K1206*	0.23
LIHC	chr5	138372724	Silent	novel	K81K	0.44
LIHC	chr5	138419011	Missense_Mutation	NA	G1165A	0.04
LIHC	chr5	138430420	Missense_Mutation	NA	H1689Y	0.09
LIHC	chr5	138420749	Silent	novel	S1253S	0.22
LIHC	chr5	138398312	Missense_Mutation	NA	Y989C	0.33
LUAD	chr5	138391447	Missense_Mutation	novel	F605L	0.25
LUAD	chr5	138391955	Missense_Mutation	rs755278940	G775S	0.21
LUAD	chr5	138391265	Missense_Mutation	NA	E545Q	0.19
LUAD	chr5	138391598	Missense_Mutation	NA	A656S	0.46
LUAD	chr5	138386596	Missense_Mutation	NA	G452D	0.24
LUAD	chr5	138393208	Silent	novel	K889K	0.2
LUAD	chr5	138391891	Silent	rs759333795	G753G	0.15
LUAD	chr5	138386183	Silent	NA	S314S	0.27
LUAD	chr5	138415239	Missense_Mutation	novel	A1103T	0.09
LUAD	chr5	138420726	Missense_Mutation	novel	V1246L	0.08
LUAD	chr5	138372821	Missense_Mutation	NA	I114F	0.48
LUAD	chr5	138392229	Missense_Mutation	NA	P866H	0.36
LUAD	chr5	138399971	Missense_Mutation	NA	C1053F	0.13
LUAD	chr5	138417513	Missense_Mutation	novel	A1113D	0.08
LUAD	chr5	138424212	Silent	NA	V1370V	0.38
LUAD	chr5	138419077	Missense_Mutation	NA	R1187K	0.12
LUAD	chr5	138372807	Missense_Mutation	novel	G109D	0.07
LUAD	chr5	138417499	Silent	novel	G1108G	0.11
LUAD	chr5	138391850	Missense_Mutation	NA	T740S	0.28
LUAD	chr5	138420729	Missense_Mutation	novel	L1247F	0.1
LUAD	chr5	138419036	Silent	NA	P1173P	0.26
LUAD	chr5	138386082	Missense_Mutation	NA	G281W	0.29
LUAD	chr5	138391972	Silent	novel	P780P	0.25
LUAD	chr5	138424127	Nonsense_Mutation	novel	S1342*	0.05
LUAD	chr5	138391526	Missense_Mutation	NA	E632Q	0.14
LUAD	chr5	138398359	Missense_Mutation	NA	E1005Q	0.3
LUSC	chr5	138427269	Missense_Mutation	NA	P1528R	0.39
LUSC	chr5	138398292	Missense_Mutation	novel	I982M	0.36
LUSC	chr5	138398293	Missense_Mutation	novel	D983H	0.16
LUSC	chr5	138398360	Missense_Mutation	novel	E1005G	0.25
LUSC	chr5	138425518	Missense_Mutation	NA	R1449S	0.28
LUSC	chr5	138420806	Silent	novel	K1272K	0.37
LUSC	chr5	138391095	Missense_Mutation	novel	G488E	0.31
LUSC	chr5	138391876	Missense_Mutation	novel	E748D	0.27
LUSC	chr5	138386204	Silent	NA	R321R	0.28
LUSC	chr5	138392154	Frame_Shift_Ins	novel	*N848Dfs13**	0.23
LUSC	chr5	138391081	Missense_Mutation	NA	L483F	0.11
LUSC	chr5	138391907	Missense_Mutation	novel	N759D	0.16
LUSC	chr5	138391708	Silent	novel	L692L	0.94
LUSC	chr5	138399873	Nonsense_Mutation	novel	W1020*	0.57
OV	chr5	138425452	Missense_Mutation	novel	E1427D	0.06
OV	chr5	138386221	Missense_Mutation	novel	G327E	0.12
OV	chr5	138391195	Frame_Shift_Del	novel	*S522Pfs43**	0.54
OV	chr5	138392175	Missense_Mutation	rs148445583	N848S	0.16
OV	chr5	138391898	Missense_Mutation	novel	Q756K	0.14
OV	chr5	138391190	Missense_Mutation	novel	D520H	0.04
OV	chr5	138424075	Missense_Mutation	novel	G1325R	0.05
OV	chr5	138424257	Silent	novel	L1385L	0.09
OV	chr5	138424223	Missense_Mutation	novel	N1374S	0.06
OV	chr5	138426992	Missense_Mutation	novel	D1477H	0.06
OV	chr5	138425435	Missense_Mutation	novel	K1422Q	0.18
OV	chr5	138392255	Missense_Mutation	NA	L875M	0.64
OV	chr5	138429961	Missense_Mutation	novel	R1630Q	0.08
OV	chr5	138393337	Missense_Mutation	novel	D932E	0.11
OV	chr5	138386306	Silent	novel	R355R	0.08
OV	chr5	138435688	Silent	NA	L1758L	0.3
PAAD	chr5	138419124	Frame_Shift_Del	novel	S1203*	0.3
PAAD	chr5	138429959	Silent	novel	L1629L	0.18
PAAD	chr5	138431544	Silent	novel	H1730H	0.22
PRAD	chr5	138428032	Missense_Mutation	novel	V1567I	0.19
PRAD	chr5	138386247	Missense_Mutation	NA	D336Y	0.2
PRAD	chr5	138392238	Missense_Mutation	NA	R869Q	0.1
PRAD	chr5	138392105	Nonsense_Mutation	novel	E825*	0.08
PRAD	chr5	138381587	Silent	rs367814427	S259S	0.49
READ	chr5	138393339	Missense_Mutation	novel	S933F	0.28
READ	chr5	138372812	Nonsense_Mutation	novel	R111*	0.04
READ	chr5	138391297	Missense_Mutation	novel	D555E	0.44
READ	chr5	138386183	Silent	NA	S314S	0.06
READ	chr5	138391241	Missense_Mutation	novel	S537R	0.35
READ	chr5	138430330	Missense_Mutation	novel	R1659C	0.48
SARC	chr5	138386505	Missense_Mutation	novel	A422S	0.1
SARC	chr5	138430422	Silent	rs541133556	H1689H	0.29
SARC	chr5	138420793	Missense_Mutation	rs763718862	P1268L	0.12
SKCM	chr5	138430401	Silent	novel	F1682F	0.4
SKCM	chr5	138430355	Missense_Mutation	novel	G1667V	0.17
SKCM	chr5	138393301	Frame_Shift_Del	novel	*R921Vfs5**	0.38
SKCM	chr5	138391690	Silent	novel	L686L	0.39
SKCM	chr5	138420866	Silent	novel	S1292S	0.52
SKCM	chr5	138419034	Missense_Mutation	NA	P1173S	0.08
SKCM	chr5	138419035	Missense_Mutation	novel	P1173L	0.08
SKCM	chr5	138430394	Missense_Mutation	NA	A1680V	0.23
SKCM	chr5	138391529	Missense_Mutation	rs751487871	P633S	0.17
SKCM	chr5	138391780	Silent	NA	S716S	0.24
SKCM	chr5	138418989	Missense_Mutation	NA	E1158K	0.64
SKCM	chr5	138425573	Missense_Mutation	NA	I1468F	0.17
SKCM	chr5	138419148	Missense_Mutation	NA	P1211S	0.44
SKCM	chr5	138431497	Missense_Mutation	NA	R1715C	0.32
SKCM	chr5	138420956	Silent	NA	S1322S	0.29
SKCM	chr5	138391686	Missense_Mutation	NA	S685F	0.73
SKCM	chr5	138427969	Splice_Region	NA	L1546L	0.45
SKCM	chr5	138429959	Silent	NA	L1629L	0.26
SKCM	chr5	138425549	Missense_Mutation	NA	R1460W	0.88
SKCM	chr5	138391765	Silent	NA	T711T	0.23
SKCM	chr5	138398361	Silent	NA	E1005E	0.4
SKCM	chr5	138420716	Silent	NA	S1242S	0.42
SKCM	chr5	138425570	Missense_Mutation	NA	E1467K	0.13
SKCM	chr5	138419148	Missense_Mutation	NA	P1211S	0.24
SKCM	chr5	138386328	Missense_Mutation	NA	N363H	0.29
SKCM	chr5	138430251	Splice_Region	NA	V1632V	0.57
SKCM	chr5	138391334	Silent	NA	L568L	0.34
SKCM	chr5	138398306	Missense_Mutation	novel	S987L	0.25
SKCM	chr5	138419017	Missense_Mutation	rs528636129	P1167L	0.24
SKCM	chr5	138379590	Frame_Shift_Del	novel	Y196*	0.23
SKCM	chr5	138391538	Missense_Mutation	NA	P636S	0.3
SKCM	chr5	138391708	Silent	NA	L692L	0.28
SKCM	chr5	138372782	Missense_Mutation	NA	R101C	0.11
SKCM	chr5	138420714	Missense_Mutation	NA	S1242A	0.87
SKCM	chr5	138420715	Missense_Mutation	rs562855380	S1242F	0.26
SKCM	chr5	138386308	Missense_Mutation	novel	F356S	0.32
SKCM	chr5	138420955	Missense_Mutation	novel	S1322F	0.43
SKCM	chr5	138391539	Missense_Mutation	NA	P636L	0.19
SKCM	chr5	138391726	Silent	rs770186676	S698S	0.56
SKCM	chr5	138420931	Missense_Mutation	NA	P1314L	0.67
SKCM	chr5	138391058	Missense_Mutation	NA	L476F	0.24
SKCM	chr5	138398206	Missense_Mutation	NA	R954C	0.63
SKCM	chr5	138391923	Missense_Mutation	novel	T764I	0.43
STAD	chr5	138391401	Missense_Mutation	NA	D590A	0.49
STAD	chr5	138420936	Frame_Shift_Del	NA	*P1317Rfs10**	0.2
STAD	chr5	138379682	Missense_Mutation	NA	R227C	0.2
STAD	chr5	138393354	Missense_Mutation	NA	R938H	0.16
STAD	chr5	138391746	Missense_Mutation	novel	V705G	0.05
STAD	chr5	138400001	Missense_Mutation	rs758977082	R1063Q	0.3
STAD	chr5	138398206	Missense_Mutation	NA	R954C	0.3
STAD	chr5	138391803	Missense_Mutation	NA	R724H	0.41
STAD	chr5	138420936	Frame_Shift_Del	NA	*P1317Rfs10**	0.23
STAD	chr5	138379586	Missense_Mutation	NA	P195S	0.36
STAD	chr5	138435654	Missense_Mutation	NA	A1747V	0.22
STAD	chr5	138427286	Missense_Mutation	novel	P1534S	0.38
STAD	chr5	138429868	Missense_Mutation	novel	T1599M	0.26
STAD	chr5	138398359	Missense_Mutation	NA	E1005Q	0.11
STAD	chr5	138386504	Silent	NA	A421A	0.07
STAD	chr5	138420941	Silent	rs144228142	P1317P	0.31
STAD	chr5	138381587	Silent	rs367814427	S259S	0.34
STAD	chr5	138393333	Missense_Mutation	NA	D931G	0.21
STAD	chr5	138386615	Silent	novel	S458S	0.25
STAD	chr5	138426991	Missense_Mutation	NA	E1476D	0.23
STAD	chr5	138420936	Frame_Shift_Del	NA	*P1317Rfs10**	0.25
STAD	chr5	138377800	Silent	NA	Q185Q	0.34
STAD	chr5	138399971	Missense_Mutation	novel	C1053Y	0.35
STAD	chr5	138381588	Missense_Mutation	NA	E260K	0.12
STAD	chr5	138391901	Nonsense_Mutation	novel	Q757*	0.31
STAD	chr5	138391389	Missense_Mutation	NA	G586V	0.21
STAD	chr5	138420936	Frame_Shift_Del	NA	*P1317Rfs10**	0.3
STAD	chr5	138372790	Silent	rs779436763	D103D	0.14
STAD	chr5	138430275	Frame_Shift_Del	novel	*P1642Lfs36**	0.21
TGCT	chr5	138393374	Splice_Site	novel	X944_splice	0.21
TGCT	chr5	138427016	Missense_Mutation	novel	L1485F	0.28
THCA	chr5	138428080	Frame_Shift_Ins	novel	*D1583Vfs4**	0.02
THCA	chr5	138391972	Frame_Shift_Del	novel	*A781Qfs14**	0.44
UCEC	chr5	138398349	Silent	rs141260024	L1001L	0.37
UCEC	chr5	138425549	Missense_Mutation	NA	R1460W	0.28
UCEC	chr5	138392194	Missense_Mutation	novel	E854D	0.56
UCEC	chr5	138391972	Silent	rs187275789	P780P	0.22
UCEC	chr5	138399962	Missense_Mutation	NA	F1050S	0.28
UCEC	chr5	138425424	Missense_Mutation	NA	S1418L	0.36
UCEC	chr5	138428064	Silent	NA	I1577I	0.29
UCEC	chr5	138379708	Splice_Region	novel	E235E	0.35
UCEC	chr5	138399982	Nonsense_Mutation	novel	Y1057*	0.47
UCEC	chr5	138391593	Missense_Mutation	NA	S654F	0.41
UCEC	chr5	138425549	Missense_Mutation	NA	R1460W	0.38
UCEC	chr5	138419147	Silent	rs201802253	P1210P	0.29
UCEC	chr5	138386520	Missense_Mutation	novel	A427T	0.55
UCEC	chr5	138420936	Frame_Shift_Del	NA	*P1317Rfs10**	0.12
UCEC	chr5	138391550	Missense_Mutation	NA	F640L	0.45
UCEC	chr5	138398219	Missense_Mutation	novel	F958S	0.3
UCEC	chr5	138391469	Missense_Mutation	rs776949034	R613C	0.41
UCEC	chr5	138426977	Nonsense_Mutation	NA	R1472*	0.39
UCEC	chr5	138381513	Splice_Region	novel		0.1
UCEC	chr5	138377759	Missense_Mutation	novel	A172T	0.39
UCEC	chr5	138424165	Missense_Mutation	rs746068888	R1355W	0.87
UCEC	chr5	138431497	Missense_Mutation	NA	R1715C	0.45
UCEC	chr5	138386469	Missense_Mutation	NA	L410M	0.33
UCEC	chr5	138415170	Silent	NA	L1080L	0.17
UCEC	chr5	138420876	Missense_Mutation	NA	L1296I	0.2
UCEC	chr5	138429936	Missense_Mutation	NA	A1622T	0.2
UCEC	chr5	138386615	Silent	rs745953070	S458S	0.38
UCEC	chr5	138391205	Silent	NA	L525L	0.49
UCEC	chr5	138391469	Missense_Mutation	rs776949034	R613C	0.43
UCEC	chr5	138375168	Missense_Mutation	rs138966363	R146W	0.24
UCEC	chr5	138391031	Missense_Mutation	NA	L467M	0.33
UCEC	chr5	138391129	Silent	NA	E499E	0.18
UCEC	chr5	138391934	Missense_Mutation	rs147174917	V768I	0.22
UCEC	chr5	138420871	Missense_Mutation	NA	R1294Q	0.12
UCEC	chr5	138427046	Nonsense_Mutation	NA	R1495*	0.16
UCEC	chr5	138386351	Missense_Mutation	novel	Q370H	0.28
UCEC	chr5	138391520	Nonsense_Mutation	novel	R630*	0.19
UCEC	chr5	138398266	Missense_Mutation	novel	P974T	0.19
UCEC	chr5	138425521	Silent	novel	N1450N	0.16
UCEC	chr5	138377736	Frame_Shift_Del	novel	*N165Tfs10**	0.12
UCEC	chr5	138430404	Missense_Mutation	novel	I1683M	0.45
UCEC	chr5	138435791	3'UTR	novel		0.5
UCEC	chr5	138419107	Missense_Mutation	rs777239432	S1197L	0.23
UCEC	chr5	138391026	Missense_Mutation	novel	S465Y	0.55
UCEC	chr5	138386063	Missense_Mutation	novel	K274N	0.18
UCEC	chr5	138399869	Missense_Mutation	novel	A1019V	0.24
UCEC	chr5	138419153	Silent	novel	C1212C	0.47
UCEC	chr5	138424273	Silent	novel	L1391L	0.2
UCEC	chr5	138392170	Frame_Shift_Del	novel	*N848Mfs28**	0.31
UCEC	chr5	138386202	Nonsense_Mutation	NA	R321*	0.11
UCEC	chr5	138430409	Missense_Mutation	novel	A1685V	0.28
UCEC	chr5	138430275	Frame_Shift_Del	novel	*P1642Lfs36**	0.16
UCEC	chr5	138391355	Missense_Mutation	novel	L575I	0.5
UCEC	chr5	138427313	Missense_Mutation	novel	A1543T	0.21
UCEC	chr5	138381587	Silent	rs367814427	S259S	0.36
UCEC	chr5	138391933	Silent	rs750944984	N767N	0.38
UCEC	chr5	138391330	Silent	NA	S566S	0.2
UCEC	chr5	138386398	Missense_Mutation	novel	S386Y	0.55
UCEC	chr5	138391520	Nonsense_Mutation	novel	R630*	0.45
UCEC	chr5	138399895	Missense_Mutation	NA	R1028W	0.47
UCEC	chr5	138415209	Missense_Mutation	novel	L1093I	0.44
UCEC	chr5	138420766	Missense_Mutation	rs371034627	S1259L	0.48
UCEC	chr5	138420919	Missense_Mutation	NA	D1310G	0.4
UCEC	chr5	138391068	Nonsense_Mutation	novel	S479*	0.63
UCEC	chr5	138379657	Silent	NA	V218V	0.34
UCEC	chr5	138391712	Missense_Mutation	rs781672306	I694V	0.39
UCEC	chr5	138391515	Missense_Mutation	novel	L628S	0.44
UCEC	chr5	138427053	Missense_Mutation	novel	M1497T	0.32
UCEC	chr5	138393284	Missense_Mutation	NA	R915C	0.52
UCEC	chr5	138391717	Silent	novel	T695T	0.17
UCEC	chr5	138424249	Missense_Mutation	novel	S1383P	0.17
UCEC	chr5	138431513	Missense_Mutation	novel	F1720C	0.12
UCEC	chr5	138391934	Missense_Mutation	rs147174917	V768I	0.38
UCEC	chr5	138399877	Nonsense_Mutation	novel	R1022*	0.53
UCEC	chr5	138392157	Frame_Shift_Ins	novel	*K844Efs11**	0.5
UCEC	chr5	138386617	Missense_Mutation	NA	G459E	0.5
UCEC	chr5	138391436	Frame_Shift_Del	NA	*T602Lfs9**	0.43
UCEC	chr5	138386029	Missense_Mutation	rs188469319	T263M	0.38
UCEC	chr5	138386183	Silent	NA	S314S	0.37
UCEC	chr5	138391845	Missense_Mutation	novel	M738T	0.33
UCEC	chr5	138430356	Silent	rs768314346	G1667G	0.44
UCEC	chr5	138415218	Missense_Mutation	novel	T1096A	0.37
UCEC	chr5	138391077	Missense_Mutation	NA	P482H	0.19
UCEC	chr5	138430405	Missense_Mutation	novel	P1684S	0.35
UCEC	chr5	138435924	3'UTR	novel		0.5
UCEC	chr5	138391090	Silent	NA	G486G	0.44
UCEC	chr5	138391686	Missense_Mutation	NA	S685Y	0.29
UCEC	chr5	138372812	Nonsense_Mutation	novel	R111*	0.17
UCEC	chr5	138428072	Missense_Mutation	NA	G1580V	0.3
UCEC	chr5	138399886	Missense_Mutation	rs763983126	R1025C	0.25
UCEC	chr5	138420838	Missense_Mutation	NA	A1283V	0.27
UCEC	chr5	138375194	Silent	novel	L154L	0.09
UCEC	chr5	138392106	Missense_Mutation	novel	E825G	0.49
UCEC	chr5	138391769	Frame_Shift_Del	NA	*G714Afs81**	0.23
UCEC	chr5	138427188	Splice_Site	novel	X1501_splice	0.26
UCEC	chr5	138391792	Frame_Shift_Del	novel	*N722Mfs73**	0.39
UCEC	chr5	138427046	Nonsense_Mutation	NA	R1495*	0.43
UCEC	chr5	138392201	Silent	novel	L857L	0.46
UCEC	chr5	138398294	Missense_Mutation	novel	D983A	0.05
UCEC	chr5	138399886	Missense_Mutation	rs763983126	R1025C	0.28
UCEC	chr5	138391884	Missense_Mutation	rs776596787	T751I	0.42
UCEC	chr5	138427312	Silent	rs368913432	N1542N	0.37
UCEC	chr5	138425424	Missense_Mutation	NA	S1418L	0.46
UCEC	chr5	138386269	Missense_Mutation	rs140546320	P343L	0.27
UCEC	chr5	138392061	Missense_Mutation	novel	S810L	0.27
UCEC	chr5	138400008	Silent	rs771317491	R1065R	0.28
UCEC	chr5	138420887	Silent	rs759554146	S1299S	0.62
UCEC	chr5	138426983	Missense_Mutation	novel	R1474W	0.3
UCEC	chr5	138428036	Missense_Mutation	novel	N1568I	0.29
UCEC	chr5	138425549	Missense_Mutation	NA	R1460W	0.31
UCEC	chr5	138393306	Missense_Mutation	novel	Y922C	0.41
UCEC	chr5	138399911	Missense_Mutation	novel	V1033A	0.37
UCEC	chr5	138391933	Silent	rs750944984	N767N	0.16
UCEC	chr5	138429900	Missense_Mutation	NA	P1610T	0.14
UCEC	chr5	138426977	Nonsense_Mutation	NA	R1472*	0.45
UCEC	chr5	138379608	Missense_Mutation	novel	R202K	0.34
UCEC	chr5	138391543	Missense_Mutation	novel	F637L	0.51
UCEC	chr5	138420854	Silent	rs772483803	T1288T	0.35
UCEC	chr5	138430341	Silent	novel	L1662L	0.28
UCS	chr5	138419226	Missense_Mutation	novel	T1237A	0.12
UVM	chr5	138415133	Splice_Region	novel	E1067E	0.22

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRP	AMP	0.1076	0.069756
KIRP	DEL	0.0382	0.11554
LAML	DEL	0.089	1.2971e-07
LUAD	DEL	0.2694	7.4776e-05
LUSC	DEL	0.6208	0.002071
MESO	DEL	0.1264	0.20184
PRAD	AMP	0.0285	0.16448
SKCM	DEL	0.2888	2.2081e-08
THCA	AMP	0.0361	0.075436
THCA	DEL	0	0.23456

Survival Analysis

Cancer	P-value	Q-value
MESO	0.023	Kaplan-Meier Survival Analysis
COAD	0.026	Kaplan-Meier Survival Analysis
READ	0.003	Kaplan-Meier Survival Analysis
LAML	0.007	Kaplan-Meier Survival Analysis
LIHC	0.01	Kaplan-Meier Survival Analysis
LGG	0.00027	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Pathway

Phenotype

GWAS

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000120733 (Gene tree)
Gene ID: 51780
Gene Symbol: KDM3B
Alias: KIAA1082|NET22|C5orf7|JMJD1B
Full Name: lysine demethylase 3B
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Plus strand
Length: 84,433 bases
Position: chr5:138,352,596-138,437,028
Accession: 1337
Summary: (Lysine Demethylase 3B) is a Protein Coding gene. Diseases associated with KDM3B include Persistent Hyperplastic Primary Vitreous. Among its related pathways are Chromatin Regulation / Acetylation and Chromatin organization. Gene Ontology (GO) annotations related to this gene include dioxygenase activity. An important paralog of this gene is JMJD1C.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000510866	KDM3B-207	6324	-	ENSP00000425186	274 (aa)	-	H0Y9V5
ENST00000508386	KDM3B-205	540	-	-	- (aa)	-	-
ENST00000509468	KDM3B-206	576	-	-	- (aa)	-	-
ENST00000504095	KDM3B-202	555	-	-	- (aa)	-	-
ENST00000512928	KDM3B-208	627	-	-	- (aa)	-	-
ENST00000507996	KDM3B-204	3034	-	ENSP00000423012	20 (aa)	-	H0Y946
ENST00000542866	KDM3B-209	3634	-	ENSP00000439462	759 (aa)	-	Q7LBC6
ENST00000314358	KDM3B-201	6813	XM_005272018	ENSP00000326563	1761 (aa)	XP_005272075	Q7LBC6
ENST00000505756	KDM3B-203	654	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000120733's gene model file

Pathway

Pathway ID	Pathway Name	Source
hsa04714	Thermogenesis	KEGG

Phenotype

ensgID	Trait	pValue	Pubmed ID
ENSG00000120733	Blood Pressure	2.8471301E-006	-
ENSG00000120733	Menarche	9E-14	25231870
ENSG00000120733	Prostatic Neoplasms	4E-8	27515689
ENSG00000120733	Electromagnetic Radiation	4E-8	27515689
ENSG00000120733	Menarche	5E-8	21102462

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000120733	rs35131895	5	138413188	?	Autism spectrum disorder or schizophrenia	28540026	[1.04-1.09]	1.0638298	EFO_0000692\|EFO_0003756
ENSG00000120733	rs17171818	5	138389314	C	Menarche (age at onset)	25231870	[0.028-0.052] unit increase	0.04	EFO_0004703
ENSG00000120733	rs757647	5	138371626	A	Menarche (age at onset)	21102462	[1.62-3.18] week decrease	2.4	EFO_0004703

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000120733's network

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000785	chromatin	21873635.	IBA	Component
GO:0000976	transcription regulatory region sequence-specific DNA binding	21873635.	IBA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0016209	antioxidant activity	-	IEA	Function
GO:0031490	chromatin DNA binding	21873635.	IBA	Function
GO:0032454	histone demethylase activity (H3-K9 specific)	21873635.	IBA	Function
GO:0033169	histone H3-K9 demethylation	21873635.	IBA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0051213	dioxygenase activity	-	IEA	Function
GO:0055114	oxidation-reduction process	-	IEA	Process
GO:0072718	response to cisplatin	-	IEA	Process
GO:0098869	cellular oxidant detoxification	-	IEA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Pathway

Phenotype

GWAS

PPI

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.