EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
26356687	Replication and Meta-Analysis of Common Gene Mutations in TTF1 and TTF2 with Papillary Thyroid Cancer.	Medicine (Baltimore)	2015 Sep	Gao Y	doi: 10.1097/MD.0000000000001246.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr1	117075524	Missense_Mutation	novel	Q314E	0.48
BLCA	chr1	117075176	Missense_Mutation	NA	E198Q	0.24
BLCA	chr1	117097408	Missense_Mutation	NA	H1082N	0.18
BLCA	chr1	117090589	Nonsense_Mutation	NA	E852*	0.27
BLCA	chr1	117086480	Missense_Mutation	novel	N706K	0.2	ResIII
BLCA	chr1	117086513	Silent	NA	L717L	0.43
BLCA	chr1	117091914	Silent	novel	L923L	0.23
BLCA	chr1	117060495	Silent	novel	P23P	0.37
BLCA	chr1	117074930	Missense_Mutation	novel	H116Y	0.26
BLCA	chr1	117060332	5'UTR	rs200495096		0.35
BLCA	chr1	117075820	Silent	novel	A412A	0.31
BLCA	chr1	117096297	Nonsense_Mutation	novel	Q1062*	0.24
BLCA	chr1	117075346	Silent	novel	L254L	0.2
BLCA	chr1	117075374	Missense_Mutation	novel	Q264E	0.35
BLCA	chr1	117091933	Missense_Mutation	novel	L930V	0.22
BLCA	chr1	117074972	Missense_Mutation	novel	D130N	0.23
BRCA	chr1	117075536	Nonsense_Mutation	NA	E318*	0.18
BRCA	chr1	117074992	Silent	NA	A136A	0.14
BRCA	chr1	117077972	Missense_Mutation	NA	G544S	0.18
BRCA	chr1	117091869	Silent	NA	S908S	0.19
BRCA	chr1	117075074	Missense_Mutation	NA	D164N	0.06
BRCA	chr1	117084042	Missense_Mutation	novel	G643E	0.22	ResIII
BRCA	chr1	117075412	Missense_Mutation	NA	Q276H	0.3
BRCA	chr1	117075564	Missense_Mutation	NA	G327A	0.27
BRCA	chr1	117076777	Missense_Mutation	rs765522575	K509N	0.11
BRCA	chr1	117091896	Silent	NA	L917L	0.2
CESC	chr1	117084070	Silent	NA	L652L	0.31
CESC	chr1	117077992	Silent	NA	L550L	0.27
CESC	chr1	117074997	Missense_Mutation	NA	W138L	0.12
CESC	chr1	117074981	Missense_Mutation	NA	Q133E	0.21
CESC	chr1	117075693	Frame_Shift_Ins	novel	*L371Sfs5**	0.1
CESC	chr1	117075694	Silent	novel	L370L	0.07
CESC	chr1	117096162	Nonsense_Mutation	NA	Q1017*	0.39
CESC	chr1	117098899	Silent	rs776200480	V1112V	0.35
CESC	chr1	117091868	Nonsense_Mutation	NA	S908*	0.36
CESC	chr1	117097351	Missense_Mutation	NA	V1063L	0.22
CESC	chr1	117075296	Missense_Mutation	NA	E238K	0.21
COAD	chr1	117075073	Silent	rs537063851	F163F	0.36
COAD	chr1	117075200	Missense_Mutation	rs370194411	A206T	0.33
COAD	chr1	117101426	Frame_Shift_Ins	NA	*K1134Efs22**	0.25
COAD	chr1	117096273	Missense_Mutation	novel	A1054T	0.32
COAD	chr1	117081896	Frame_Shift_Del	novel	*K619Rfs10**	0.36	ResIII
COAD	chr1	117075617	Missense_Mutation	rs748574887	R345C	0.42
COAD	chr1	117076707	Missense_Mutation	novel	P486H	0.33
COAD	chr1	117101765	3'UTR	novel		0.33
COAD	chr1	117075396	Missense_Mutation	novel	S271L	0.29
COAD	chr1	117090210	Splice_Site	novel	X832_splice	0.14
COAD	chr1	117077935	Silent	rs754685562	H531H	0.45
COAD	chr1	117098836	Missense_Mutation	NA	N1091K	0.3
COAD	chr1	117091390	Missense_Mutation	NA	P884H	0.31
COAD	chr1	117090625	Splice_Site	novel	X863_splice	0.34
COAD	chr1	117074911	Missense_Mutation	rs776227653	Q109H	0.33
COAD	chr1	117078032	Missense_Mutation	rs752455144	A564T	0.13
COAD	chr1	117092852	Missense_Mutation	rs761218230	G976D	0.3
ESCA	chr1	117090209	Splice_Site	novel	X832_splice	0.19
ESCA	chr1	117091880	Missense_Mutation	novel	S912I	0.08
ESCA	chr1	117060337	5'UTR	novel		0.15
GBM	chr1	117060483	Silent	NA	V19V	0.39
GBM	chr1	117075538	Missense_Mutation	novel	E318D	0.22
GBM	chr1	117075436	Silent	NA	E284E	0.27
HNSC	chr1	117081833	Missense_Mutation	rs747286626	D597N	0.17	ResIII
HNSC	chr1	117075742	Silent	novel	F386F	0.13
HNSC	chr1	117076654	Missense_Mutation	novel	K468N	0.09
HNSC	chr1	117088808	Nonsense_Mutation	novel	S723*	0.21	ResIII
HNSC	chr1	117088823	Missense_Mutation	rs200362905	R728Q	0.25	ResIII
HNSC	chr1	117081914	Nonsense_Mutation	novel	K624*	0.08	ResIII
HNSC	chr1	117101521	Silent	novel	I1162I	0.09
HNSC	chr1	117101642	3'UTR	novel		0.1
HNSC	chr1	117075534	Missense_Mutation	rs367793200	P317L	0.3
KIRP	chr1	117090550	Nonsense_Mutation	NA	K839*	0.23
KIRP	chr1	117076245	Missense_Mutation	NA	I447M	0.39
LGG	chr1	117084074	Missense_Mutation	novel	H654Y	0.07	ResIII
LIHC	chr1	117075485	Missense_Mutation	NA	I301L	0.5
LUAD	chr1	117062439	Missense_Mutation	NA	G62C	0.07
LUAD	chr1	117060324	5'UTR	novel		0.1
LUAD	chr1	117091408	Missense_Mutation	novel	R890K	0.07
LUAD	chr1	117084095	Nonsense_Mutation	NA	E661*	0.16	ResIII
LUAD	chr1	117076729	Silent	rs751511614	Q493Q	0.09
LUAD	chr1	117076278	Silent	novel	T458T	0.46
LUAD	chr1	117084040	Silent	novel	H642H	0.23
LUAD	chr1	117081840	Missense_Mutation	novel	G599A	0.18	ResIII
LUAD	chr1	117079602	Missense_Mutation	novel	A579D	0.25	ResIII
LUAD	chr1	117090063	Missense_Mutation	NA	R784L	0.15
LUAD	chr1	117090543	Silent	rs774666971	P836P	0.3
LUAD	chr1	117075639	Missense_Mutation	novel	D352G	0.09
LUAD	chr1	117073724	Missense_Mutation	NA	W94C	0.08
LUAD	chr1	117076725	Missense_Mutation	novel	P492L	0.11
LUSC	chr1	117096152	Silent	novel	V1013V	0.21
LUSC	chr1	117088949	Missense_Mutation	NA	Q770R	0.43
LUSC	chr1	117060487	Missense_Mutation	novel	D21Y	0.08
LUSC	chr1	117088952	Missense_Mutation	NA	N771S	0.13
LUSC	chr1	117091858	Missense_Mutation	novel	A905P	0.09
LUSC	chr1	117086513	Silent	rs757847842	L717L	0.15
LUSC	chr1	117097400	Missense_Mutation	novel	G1079A	0.42
LUSC	chr1	117075150	Missense_Mutation	novel	S189C	0.13
LUSC	chr1	117090134	Silent	novel	R808R	0.18
LUSC	chr1	117073705	Nonsense_Mutation	novel	W88*	0.13
OV	chr1	117075458	Nonsense_Mutation	novel	E292*	0.11
OV	chr1	117086442	Missense_Mutation	NA	T694S	0.1	ResIII
OV	chr1	117075210	Missense_Mutation	novel	G209E	0.09
OV	chr1	117092746	Missense_Mutation	novel	E941K	0.31
OV	chr1	117075297	Missense_Mutation	novel	E238V	0.11
OV	chr1	117092787	Silent	novel	Q954Q	0.15
OV	chr1	117092839	Missense_Mutation	novel	V972L	0.08
PAAD	chr1	117076242	Missense_Mutation	novel	Q446H	0.2
PRAD	chr1	117076705	Silent	novel	G485G	0.18
READ	chr1	117101405	Nonsense_Mutation	novel	E1124*	0.38
READ	chr1	117092884	Missense_Mutation	novel	M987L	0.24
READ	chr1	117073681	Missense_Mutation	novel	R80I	0.42
READ	chr1	117090059	Missense_Mutation	novel	L783I	0.37
READ	chr1	117101456	Missense_Mutation	novel	L1141I	0.4
READ	chr1	117062442	Missense_Mutation	NA	L63V	0.41
READ	chr1	117075227	Missense_Mutation	NA	D215Y	0.25
SARC	chr1	117078031	Silent	rs777393770	P563P	0.79
SKCM	chr1	117090599	Missense_Mutation	novel	Y855C	0.27
SKCM	chr1	117075073	Silent	rs537063851	F163F	0.2
SKCM	chr1	117101475	Missense_Mutation	novel	S1147F	0.31
SKCM	chr1	117092844	Silent	NA	S973S	0.17
SKCM	chr1	117084107	Missense_Mutation	NA	N665D	0.15	ResIII
SKCM	chr1	117088920	Silent	rs747079505	A760A	0.22
SKCM	chr1	117101557	3'UTR	novel		0.09
SKCM	chr1	117088889	Missense_Mutation	novel	S750F	0.63	ResIII
SKCM	chr1	117092843	Missense_Mutation	NA	S973F	0.56
SKCM	chr1	117090543	Silent	rs774666971	P836P	0.59
SKCM	chr1	117091939	Missense_Mutation	NA	L932V	0.23
SKCM	chr1	117101510	Missense_Mutation	NA	L1159F	0.06
SKCM	chr1	117092834	Missense_Mutation	novel	S970F	0.23
SKCM	chr1	117092835	Silent	novel	S970S	0.24
SKCM	chr1	117090556	Nonsense_Mutation	NA	Q841*	0.24
SKCM	chr1	117075832	Silent	NA	Y416Y	0.55
SKCM	chr1	117076214	Missense_Mutation	NA	P437L	0.22
SKCM	chr1	117086435	Silent	rs763073146	I691I	0.23
SKCM	chr1	117075723	Missense_Mutation	NA	T380R	0.14
SKCM	chr1	117098891	Missense_Mutation	novel	D1110N	0.36
SKCM	chr1	117101456	Silent	novel	L1141L	0.43
SKCM	chr1	117075617	Missense_Mutation	rs748574887	R345C	0.33
STAD	chr1	117075778	Silent	rs370517777	A398A	0.24
STAD	chr1	117076182	Splice_Region	novel	S426S	0.17
STAD	chr1	117077985	Missense_Mutation	rs137921158	R548H	0.27
STAD	chr1	117101426	Frame_Shift_Ins	NA	*K1134Efs22**	0.17
STAD	chr1	117084035	Missense_Mutation	novel	S641P	0.09	ResIII
STAD	chr1	117075821	Missense_Mutation	rs148191511	R413W	0.29
STAD	chr1	117075227	Missense_Mutation	NA	D215N	0.37
STAD	chr1	117088838	Missense_Mutation	rs759255274	R733Q	0.44	ResIII
STAD	chr1	117090149	Missense_Mutation	NA	T813A	0.28
STAD	chr1	117075610	Silent	novel	G342G	0.4
STAD	chr1	117101765	3'UTR	novel		0.44
STAD	chr1	117075074	Missense_Mutation	NA	D164N	0.19
STAD	chr1	117091865	Missense_Mutation	NA	D907V	0.13
STAD	chr1	117090132	Missense_Mutation	NA	E807G	0.3
STAD	chr1	117090607	Frame_Shift_Del	NA	*F859Lfs12**	0.29
STAD	chr1	117092747	Missense_Mutation	novel	E941A	0.61
STAD	chr1	117097433	Splice_Site	novel	X1090_splice	0.34
STAD	chr1	117098876	Missense_Mutation	NA	V1105I	0.21
STAD	chr1	117086457	Missense_Mutation	novel	V699M	0.41	ResIII
STAD	chr1	117086465	Missense_Mutation	NA	K701N	0.33	ResIII
STAD	chr1	117090110	Missense_Mutation	novel	N800Y	0.43
STAD	chr1	117084101	Missense_Mutation	rs557240757	R663W	0.07	ResIII
THCA	chr1	117081846	Missense_Mutation	novel	G601E	0.35	ResIII
THCA	chr1	117076275	In_Frame_Ins	novel	L457_T458insLNMCAK	0.07
UCEC	chr1	117060469	Missense_Mutation	NA	L15I	0.32
UCEC	chr1	117075161	Nonsense_Mutation	NA	E193*	0.33
UCEC	chr1	117101614	3'UTR	novel		0.28
UCEC	chr1	117075406	Missense_Mutation	rs764991907	K274N	0.32
UCEC	chr1	117075710	Missense_Mutation	NA	L376M	0.1
UCEC	chr1	117075706	Silent	NA	S374S	0.32
UCEC	chr1	117077966	Missense_Mutation	novel	A542T	0.15
UCEC	chr1	117084028	Silent	NA	D638D	0.37
UCEC	chr1	117101456	Missense_Mutation	novel	L1141I	0.32
UCEC	chr1	117101405	Nonsense_Mutation	novel	E1124*	0.34
UCEC	chr1	117060551	Missense_Mutation	novel	A42V	0.41
UCEC	chr1	117096236	Silent	novel	G1041G	0.43
UCEC	chr1	117076264	Missense_Mutation	novel	L454I	0.44
UCEC	chr1	117092788	Missense_Mutation	NA	L955I	0.27
UCEC	chr1	117074912	Missense_Mutation	NA	H110Y	0.16
UCEC	chr1	117086457	Missense_Mutation	novel	V699M	0.2	ResIII
UCEC	chr1	117090089	Silent	rs754785711	L793L	0.2
UCEC	chr1	117062440	Missense_Mutation	NA	G62D	0.4
UCEC	chr1	117088895	Missense_Mutation	NA	A752D	0.46	ResIII
UCEC	chr1	117090596	Missense_Mutation	NA	V854A	0.5
UCEC	chr1	117075073	Silent	rs537063851	F163F	0.5
UCEC	chr1	117084016	Splice_Site	rs754001847	X635_splice	0.34
UCEC	chr1	117101413	Silent	novel	I1126I	0.3
UCEC	chr1	117101426	Frame_Shift_Ins	NA	*K1134Efs22**	0.35
UCEC	chr1	117075749	Nonsense_Mutation	rs747413282	R389*	0.5
UCEC	chr1	117076678	Missense_Mutation	novel	Q476H	0.47
UCEC	chr1	117081867	Missense_Mutation	rs749221941	A608V	0.47	ResIII
UCEC	chr1	117101456	Missense_Mutation	novel	L1141I	0.66
UCEC	chr1	117075274	Silent	rs763190897	T230T	0.47
UCEC	chr1	117084052	Silent	rs776557042	I646I	0.47
UCEC	chr1	117096194	Silent	novel	L1027L	0.18
UCEC	chr1	117075303	Nonsense_Mutation	novel	S240*	0.26
UCEC	chr1	117088822	Nonsense_Mutation	rs376286717	R728*	0.17	ResIII
UCEC	chr1	117094704	Intron	rs576504987		0.38
UCEC	chr1	117086498	Silent	rs371774267	I712I	0.29
UCEC	chr1	117062466	Nonsense_Mutation	novel	E71*	0.51
UCEC	chr1	117076272	Silent	novel	G456G	0.37
UCEC	chr1	117090057	Missense_Mutation	novel	F782C	0.38
UCEC	chr1	117101456	Missense_Mutation	novel	L1141I	0.31
UCEC	chr1	117075366	Missense_Mutation	NA	L261P	0.11
UCEC	chr1	117076821	Missense_Mutation	rs755977445	R524Q	0.18
UCEC	chr1	117075316	Missense_Mutation	NA	S244R	0.36
UCEC	chr1	117062462	Missense_Mutation	novel	K69N	0.2
UCEC	chr1	117086425	Missense_Mutation	novel	T688I	0.41	ResIII
UCEC	chr1	117091949	Missense_Mutation	rs753420952	S935L	0.67
UCEC	chr1	117101414	Missense_Mutation	NA	L1127V	0.35
UCEC	chr1	117075531	Missense_Mutation	rs757979726	R316Q	0.39
UCEC	chr1	117081931	Silent	rs760111762	T629T	0.07
UCEC	chr1	117073671	Nonsense_Mutation	rs770252707	R77*	0.28
UCEC	chr1	117075723	Missense_Mutation	rs377097315	T380M	0.26
UCEC	chr1	117076742	Missense_Mutation	novel	R498C	0.22
UCEC	chr1	117092761	Missense_Mutation	novel	G946C	0.23
UCEC	chr1	117088974	Silent	NA	S778S	0.23

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	DEL	0.0915	0.01281
COAD	DEL	0.2062	0.00038973
DLBC	DEL	0.1875	0.0017831
HNSC	DEL	0.2011	7.836e-19
LUAD	DEL	0.2287	2.5961e-13
LUSC	DEL	0.3772	1.8628e-17
READ	DEL	0.2667	0.013822
SKCM	DEL	0.1662	9.7877e-07
STAD	DEL	0.1678	0.0040659
TGCT	AMP	0.2133	0.088103
UVM	DEL	0.2375	0.061261

Survival Analysis

Cancer	P-value	Q-value
STAD	0.0022	Kaplan-Meier Survival Analysis
SARC	0.0015	Kaplan-Meier Survival Analysis
MESO	0.019	Kaplan-Meier Survival Analysis
ACC	0.046	Kaplan-Meier Survival Analysis
UCS	0.023	Kaplan-Meier Survival Analysis
PRAD	0.011	Kaplan-Meier Survival Analysis
LUSC	0.0071	Kaplan-Meier Survival Analysis
KIRP	0.02	Kaplan-Meier Survival Analysis
COAD	0.036	Kaplan-Meier Survival Analysis
READ	0.00027	Kaplan-Meier Survival Analysis
KICH	0.00044	Kaplan-Meier Survival Analysis
UCEC	0.0075	Kaplan-Meier Survival Analysis
LIHC	0.00028	Kaplan-Meier Survival Analysis
LUAD	0.037	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000116830 (Gene tree)
Gene ID: 8458
Gene Symbol: TTF2
Alias: HuF2|ZGRF6
Full Name: transcription termination factor 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 47,166 bases
Position: chr1:117,060,288-117,107,453
Accession: 12398
RBP type: canonical RBP
Summary: This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000358478	ResIII	PF04851.15	1.2e-09	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000469638	TTF2-204	775	-	-	- (aa)	-	-
ENST00000480701	TTF2-206	983	-	-	- (aa)	-	-
ENST00000492682	TTF2-207	803	-	-	- (aa)	-	-
ENST00000427271	TTF2-202	639	-	ENSP00000408111	143 (aa)	-	X6RI15
ENST00000369466	TTF2-201	9462	XM_005271277	ENSP00000358478	1162 (aa)	XP_005271334	Q9UNY4
ENST00000470935	TTF2-205	849	-	-	- (aa)	-	-
ENST00000463696	TTF2-203	662	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000116830's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04918	Thyroid hormone synthesis	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000116830	Cholesterol, LDL	6.2423901013456E-7	17903299
ENSG00000116830	Cholesterol	2.41172409736342E-7	17903299
ENSG00000116830	Echocardiography	9.86864862322094E-11	17903301
ENSG00000116830	Echocardiography	1.46964834433505E-12	17903301

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000116830's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000116830	TTF2	85	35.246	ENSG00000173575	CHD2	85	38.542

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000116830	TTF2	100	80.556	ENSAPLG00000010324	-	100	53.742	Anas_platyrhynchos
ENSG00000116830	TTF2	100	99.301	ENSANAG00000020654	TTF2	100	91.316	Aotus_nancymaae
ENSG00000116830	TTF2	100	90.909	ENSBTAG00000015392	TTF2	100	76.778	Bos_taurus
ENSG00000116830	TTF2	100	91.608	ENSCHIG00000020785	TTF2	98	75.571	Capra_hircus
ENSG00000116830	TTF2	100	99.301	ENSCCAG00000032675	TTF2	100	91.144	Cebus_capucinus
ENSG00000116830	TTF2	71	65.686	ENSCSAVG00000002857	-	100	37.453	Ciona_savignyi
ENSG00000116830	TTF2	100	100.000	ENSCANG00000032079	TTF2	100	95.790	Colobus_angolensis_palliatus
ENSG00000116830	TTF2	100	77.622	ENSDORG00000013781	Ttf2	100	64.333	Dipodomys_ordii
ENSG00000116830	TTF2	100	52.083	FBgn0002542	lds	77	37.382	Drosophila_melanogaster
ENSG00000116830	TTF2	100	94.406	ENSECAG00000012474	TTF2	100	83.616	Equus_caballus
ENSG00000116830	TTF2	100	88.811	ENSFCAG00000001981	TTF2	100	72.161	Felis_catus
ENSG00000116830	TTF2	85	48.378	ENSGALG00000015249	-	99	47.256	Gallus_gallus
ENSG00000116830	TTF2	100	72.222	ENSGAFG00000004358	TTF2	99	47.049	Gambusia_affinis
ENSG00000116830	TTF2	100	99.301	ENSGGOG00000015790	TTF2	100	98.623	Gorilla_gorilla
ENSG00000116830	TTF2	100	92.308	ENSJJAG00000015225	Ttf2	100	72.151	Jaculus_jaculus
ENSG00000116830	TTF2	100	93.299	ENSMNEG00000042285	TTF2	100	93.299	Macaca_nemestrina
ENSG00000116830	TTF2	100	100.000	ENSMLEG00000041549	TTF2	100	95.533	Mandrillus_leucophaeus
ENSG00000116830	TTF2	100	79.861	ENSMGAG00000014354	TTF2	100	53.529	Meleagris_gallopavo
ENSG00000116830	TTF2	100	93.007	ENSMOCG00000008415	Ttf2	99	69.257	Microtus_ochrogaster
ENSG00000116830	TTF2	99	85.315	ENSMODG00000005145	TTF2	98	62.066	Monodelphis_domestica
ENSG00000116830	TTF2	100	72.222	ENSMALG00000017262	TTF2	98	54.796	Monopterus_albus
ENSG00000116830	TTF2	100	92.308	MGP_CAROLIEiJ_G0025427	Ttf2	100	70.377	Mus_caroli
ENSG00000116830	TTF2	100	92.308	ENSMUSG00000033222	Ttf2	100	70.240	Mus_musculus
ENSG00000116830	TTF2	100	93.706	MGP_PahariEiJ_G0026871	Ttf2	100	69.710	Mus_pahari
ENSG00000116830	TTF2	100	91.608	MGP_SPRETEiJ_G0026377	Ttf2	100	70.497	Mus_spretus
ENSG00000116830	TTF2	100	93.706	ENSMLUG00000013908	TTF2	100	79.299	Myotis_lucifugus
ENSG00000116830	TTF2	100	95.105	ENSNGAG00000018882	Ttf2	100	75.578	Nannospalax_galili
ENSG00000116830	TTF2	67	76.289	ENSNBRG00000011914	TTF2	86	55.128	Neolamprologus_brichardi
ENSG00000116830	TTF2	100	100.000	ENSNLEG00000005209	TTF2	100	96.644	Nomascus_leucogenys
ENSG00000116830	TTF2	100	95.804	ENSOCUG00000000613	TTF2	100	76.455	Oryctolagus_cuniculus
ENSG00000116830	TTF2	100	90.909	ENSOGAG00000009039	TTF2	100	78.186	Otolemur_garnettii
ENSG00000116830	TTF2	100	91.608	ENSOARG00000020266	TTF2	100	75.533	Ovis_aries
ENSG00000116830	TTF2	100	100.000	ENSPPAG00000027542	TTF2	100	99.225	Pan_paniscus
ENSG00000116830	TTF2	100	99.301	ENSPTRG00000001162	TTF2	100	99.139	Pan_troglodytes
ENSG00000116830	TTF2	100	79.167	ENSPSIG00000005266	TTF2	99	65.272	Pelodiscus_sinensis
ENSG00000116830	TTF2	85	58.644	ENSPCIG00000003483	TTF2	90	58.153	Phascolarctos_cinereus
ENSG00000116830	TTF2	100	95.009	ENSPPYG00000000976	TTF2	100	95.009	Pongo_abelii
ENSG00000116830	TTF2	100	93.706	ENSPCOG00000000551	TTF2	100	84.147	Propithecus_coquereli
ENSG00000116830	TTF2	100	95.105	ENSPVAG00000014881	TTF2	100	77.015	Pteropus_vampyrus
ENSG00000116830	TTF2	100	100.000	ENSRBIG00000042651	TTF2	100	94.872	Rhinopithecus_bieti
ENSG00000116830	TTF2	100	100.000	ENSRROG00000013287	TTF2	100	95.615	Rhinopithecus_roxellana
ENSG00000116830	TTF2	100	99.301	ENSSBOG00000022555	TTF2	100	89.252	Saimiri_boliviensis_boliviensis
ENSG00000116830	TTF2	100	81.944	ENSSHAG00000018195	TTF2	100	60.928	Sarcophilus_harrisii
ENSG00000116830	TTF2	100	74.306	ENSSMAG00000007532	TTF2	72	58.263	Scophthalmus_maximus
ENSG00000116830	TTF2	100	72.917	ENSSDUG00000013617	TTF2	99	47.720	Seriola_dumerili
ENSG00000116830	TTF2	100	92.308	ENSSARG00000007562	TTF2	100	64.175	Sorex_araneus
ENSG00000116830	TTF2	100	91.608	ENSSSCG00000006733	TTF2	100	75.257	Sus_scrofa
ENSG00000116830	TTF2	61	52.782	ENSTRUG00000015592	-	66	52.782	Takifugu_rubripes
ENSG00000116830	TTF2	100	72.603	ENSTNIG00000015679	-	85	55.726	Tetraodon_nigroviridis
ENSG00000116830	TTF2	100	74.825	ENSTTRG00000012884	TTF2	100	74.379	Tursiops_truncatus
ENSG00000116830	TTF2	91	69.418	ENSVPAG00000008276	TTF2	97	69.418	Vicugna_pacos
ENSG00000116830	TTF2	74	45.791	ENSXETG00000022003	-	100	45.791	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003677	DNA binding	-	IEA	Function
GO:0004386	helicase activity	-	IEA	Function
GO:0005515	protein binding	12927788.17577209.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005681	spliceosomal complex	-	IEA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006353	DNA-templated transcription, termination	9748214.	TAS	Process
GO:0006369	termination of RNA polymerase II transcription	9748214.	TAS	Process
GO:0006397	mRNA processing	-	IEA	Process
GO:0008023	transcription elongation factor complex	9748214.	TAS	Component
GO:0008094	DNA-dependent ATPase activity	9748214.	TAS	Function
GO:0008270	zinc ion binding	-	IEA	Function
GO:0008380	RNA splicing	-	IEA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Input Drug :

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Paralogs

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.