EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
22842912	Overexpression of the structural maintenance of chromosome 4 protein is associated with tumor de-differentiation, advanced stage and vascular invasion of primary liver cancer.	Oncol Rep	2012 Oct	Zhou B	doi: 10.3892/or.2012.1929

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr3	160431146	Missense_Mutation	rs750051763	E1019Q	0.24
ACC	chr3	160431049	Missense_Mutation	novel	I986M	0.32
ACC	chr3	160430743	Missense_Mutation	novel	E980D	0.04
BLCA	chr3	160420766	Silent	novel	K628K	0.16
BLCA	chr3	160404785	Intron	novel		0.28
BLCA	chr3	160428857	Missense_Mutation	NA	D904H	0.07
BLCA	chr3	160432361	Missense_Mutation	NA	D1126H	0.2
BLCA	chr3	160426100	Missense_Mutation	novel	L835F	0.07
BLCA	chr3	160423448	Missense_Mutation	rs754076886	M681I	0.38
BLCA	chr3	160420770	Missense_Mutation	NA	D630H	0.11
BLCA	chr3	160432361	Missense_Mutation	NA	D1126H	0.17
BLCA	chr3	160433808	Frame_Shift_Del	novel	/X1289/X	0.19
BLCA	chr3	160426092	Missense_Mutation	novel	E833K	0.07
BLCA	chr3	160419403	Missense_Mutation	NA	K573E	0.3
BLCA	chr3	160419427	Nonsense_Mutation	NA	Q581*	0.07
BLCA	chr3	160404337	Missense_Mutation	novel	D174N	0.19
BLCA	chr3	160404748	Intron	novel		0.08
BLCA	chr3	160402860	Frame_Shift_Ins	novel	*D169Lfs33**	0.12
BLCA	chr3	160431062	Missense_Mutation	rs747478933	R991C	0.25
BLCA	chr3	160401953	Missense_Mutation	rs771029178	E60K	0.24
BLCA	chr3	160431146	Missense_Mutation	rs750051763	E1019Q	0.07
BLCA	chr3	160426075	Missense_Mutation	novel	R827L	0.07
BLCA	chr3	160431119	Missense_Mutation	novel	D1010H	0.53
BLCA	chr3	160402855	Missense_Mutation	novel	K166N	0.06
BLCA	chr3	160400867	Missense_Mutation	novel	R14T	0.36
BLCA	chr3	160401916	Splice_Region	novel	E47E	0.25
BRCA	chr3	160404823	Intron	NA		0.33
BRCA	chr3	160428873	Missense_Mutation	NA	I909R	0.17
BRCA	chr3	160428841	Silent	NA	K898K	0.34
BRCA	chr3	160404458	Missense_Mutation	rs753147258	R214Q	0.24
BRCA	chr3	160423488	Missense_Mutation	rs748833024	D695H	0.27
BRCA	chr3	160431152	Frame_Shift_Del	NA	*I1021Rfs6**	0.2
BRCA	chr3	160414500	Nonsense_Mutation	NA	Q419*	0.23
BRCA	chr3	160420862	Missense_Mutation	NA	R660S	0.14
BRCA	chr3	160413602	Silent	NA	K370K	0.31
BRCA	chr3	160431186	Missense_Mutation	novel	I1032K	0.05
BRCA	chr3	160401935	Missense_Mutation	NA	D54H	0.39
CESC	chr3	160419503	Frame_Shift_Del	NA	*K608Nfs15**	0.44
CESC	chr3	160433879	3'UTR	novel		0.24
CESC	chr3	160402061	Missense_Mutation	novel	A96S	0.16
CESC	chr3	160399656	5'Flank	novel		0.49
CESC	chr3	160423593	Missense_Mutation	novel	Q730E	0.15
CESC	chr3	160431781	Missense_Mutation	NA	E1085K	0.2
CESC	chr3	160417887	Silent	NA	L534L	0.4
CESC	chr3	160424942	Missense_Mutation	NA	E801K	0.12
CESC	chr3	160433171	Missense_Mutation	NA	D1226H	0.37
CESC	chr3	160416326	Missense_Mutation	novel	E450Q	0.28
CESC	chr3	160404630	Intron	novel		0.08
CESC	chr3	160428857	Missense_Mutation	NA	D904N	0.23
CESC	chr3	160416248	Splice_Region	novel		0.15
CESC	chr3	160433868	3'UTR	novel		0.46
CHOL	chr3	160414258	Intron	novel		0.45
COAD	chr3	160412551	Intron	novel		0.33
COAD	chr3	160404457	Nonsense_Mutation	rs368979205	R214*	0.4
COAD	chr3	160430630	Missense_Mutation	NA	R943C	0.34
COAD	chr3	160433931	3'UTR	novel		0.1
COAD	chr3	160404775	Intron	novel		0.1
COAD	chr3	160402679	Missense_Mutation	novel	F108V	0.3
COAD	chr3	160423482	Missense_Mutation	novel	L693V	0.26
COAD	chr3	160412551	Intron	novel		0.24
COAD	chr3	160412049	Missense_Mutation	NA	R273G	0.4
COAD	chr3	160404645	Intron	rs758766250		0.25
COAD	chr3	160412577	Intron	novel		0.11
COAD	chr3	160401926	Nonsense_Mutation	novel	E51*	0.46
COAD	chr3	160420740	Missense_Mutation	novel	G620W	0.33
COAD	chr3	160417771	Missense_Mutation	rs543973379	R496C	0.2
COAD	chr3	160423519	Missense_Mutation	rs776113181	R705H	0.26
COAD	chr3	160424867	Missense_Mutation	NA	V776I	0.27
COAD	chr3	160402673	Splice_Region	novel		0.12
COAD	chr3	160402068	Missense_Mutation	NA	E98G	0.43
COAD	chr3	160416365	Missense_Mutation	novel	V463I	0.08
COAD	chr3	160417819	Missense_Mutation	rs779745638	R512C	0.25
COAD	chr3	160420762	Frame_Shift_Del	novel	*K628Nfs23**	0.11
COAD	chr3	160417727	Missense_Mutation	rs756108826	R481Q	0.38
COAD	chr3	160433912	3'UTR	novel		0.15
COAD	chr3	160424961	Missense_Mutation	NA	L807S	0.32
COAD	chr3	160433696	Nonsense_Mutation	rs753471840	R1252*	0.32
COAD	chr3	160423518	Missense_Mutation	rs760971978	R705C	0.2
COAD	chr3	160416372	Frame_Shift_Ins	novel	*D465Efs32**	0.12
COAD	chr3	160413490	Missense_Mutation	rs779373182	R333Q	0.16
COAD	chr3	160404470	Missense_Mutation	novel	I218T	0.22
COAD	chr3	160424975	Nonsense_Mutation	NA	R812*	0.35
DLBC	chr3	160412374	Missense_Mutation	NA	E301K	0.38
ESCA	chr3	160402854	Splice_Site	novel	X166_splice	0.2
ESCA	chr3	160431815	Missense_Mutation	novel	Y1096C	0.77
ESCA	chr3	160420800	Silent	novel	L640L	0.34
ESCA	chr3	160417939	Missense_Mutation	novel	E552Q	0.12
ESCA	chr3	160399465	5'Flank	novel		0.08
GBM	chr3	160401966	Missense_Mutation	novel	S64N	0.14
GBM	chr3	160404488	Missense_Mutation	novel	R224I	0.14
GBM	chr3	160423518	Missense_Mutation	rs760971978	R705C	0.33
GBM	chr3	160433900	3'UTR	novel		0.29
HNSC	chr3	160431079	Missense_Mutation	novel	E996D	0.12
HNSC	chr3	160419539	Missense_Mutation	novel	R618I	0.09
HNSC	chr3	160431808	Missense_Mutation	rs11548868	A1094T	0.63
HNSC	chr3	160417782	Missense_Mutation	novel	M499I	0.2
HNSC	chr3	160419503	Frame_Shift_Del	NA	*K608Nfs15**	0.26
HNSC	chr3	160432457	Missense_Mutation	novel	D1158N	0.07
HNSC	chr3	160432374	Frame_Shift_Del	novel	*R1131Gfs11**	0.36
HNSC	chr3	160423565	Missense_Mutation	novel	N720K	0.12
HNSC	chr3	160402841	Missense_Mutation	novel	V162F	0.17
KIRC	chr3	160433665	Frame_Shift_Del	novel	*N1243Mfs5**	0.2
KIRC	chr3	160432432	Nonsense_Mutation	novel	*Y1150Lfs4**	0.06
KIRC	chr3	160413470	Splice_Region	novel		0.42
LAML	chr3	160426119	Missense_Mutation	novel	L842F	0.03
LGG	chr3	160404338	Missense_Mutation	NA	D174A	0.24
LGG	chr3	160431666	Silent	novel	P1046P	0.44
LGG	chr3	160423787	Missense_Mutation	NA	V758L	0.2
LGG	chr3	160431063	Missense_Mutation	rs755432637	R991H	0.41
LGG	chr3	160431711	Missense_Mutation	novel	E1061D	0.07
LGG	chr3	160419511	Missense_Mutation	NA	S609T	0.38
LIHC	chr3	160423566	Missense_Mutation	NA	L721V	0.26
LIHC	chr3	160430617	Silent	novel	Q938Q	0.36
LIHC	chr3	160430626	Silent	novel	V941V	0.39
LIHC	chr3	160416326	Nonsense_Mutation	NA	E450*	0.38
LUAD	chr3	160431190	In_Frame_Ins	novel	K1033_Y1034insAFKFTN	0.11
LUAD	chr3	160412386	Missense_Mutation	novel	A305T	0.44
LUAD	chr3	160416350	Missense_Mutation	novel	K458E	0.06
LUAD	chr3	160417877	Missense_Mutation	NA	S531C	0.22
LUAD	chr3	160412042	Frame_Shift_Del	novel	*L270Ffs8**	0.17
LUAD	chr3	160424935	Silent	novel	V798V	0.17
LUAD	chr3	160416372	In_Frame_Ins	novel	D465delinsEHTSLC	0.12
LUAD	chr3	160419452	Missense_Mutation	novel	S589L	0.33
LUAD	chr3	160416292	Silent	novel	I438I	0.18
LUAD	chr3	160428808	Missense_Mutation	novel	L887F	0.08
LUAD	chr3	160419380	Missense_Mutation	NA	L565H	0.18
LUAD	chr3	160412047	Missense_Mutation	rs183816398	R272Q	0.09
LUAD	chr3	160402706	Missense_Mutation	NA	S117C	0.27
LUAD	chr3	160424870	Missense_Mutation	NA	N777Y	0.16
LUAD	chr3	160433153	Missense_Mutation	NA	E1220K	0.14
LUAD	chr3	160428855	Missense_Mutation	NA	Q903L	0.43
LUAD	chr3	160416372	In_Frame_Ins	novel	D465delinsEHTS	0.07
LUAD	chr3	160431781	Missense_Mutation	NA	E1085K	0.06
LUAD	chr3	160411920	Missense_Mutation	novel	G230C	0.22
LUAD	chr3	160412413	Missense_Mutation	NA	E314K	0.73
LUAD	chr3	160402725	Missense_Mutation	rs771547168	I123T	0.13
LUAD	chr3	160420860	Missense_Mutation	novel	R660G	0.25
LUSC	chr3	160414471	Missense_Mutation	novel	S409N	0.49
LUSC	chr3	160430725	Silent	novel	K974K	0.23
LUSC	chr3	160428865	Silent	novel	L906L	0.13
LUSC	chr3	160431673	Missense_Mutation	novel	D1049H	0.1
LUSC	chr3	160433032	Silent	novel	R1179R	0.21
LUSC	chr3	160400849	Missense_Mutation	NA	P8L	0.26
LUSC	chr3	160423832	Missense_Mutation	novel	E773K	0.22
LUSC	chr3	160402001	Missense_Mutation	novel	E76Q	0.09
LUSC	chr3	160404673	Intron	NA		0.17
LUSC	chr3	160431761	Missense_Mutation	novel	L1078R	0.07
LUSC	chr3	160423600	Missense_Mutation	novel	D732V	0.19
LUSC	chr3	160432458	Missense_Mutation	novel	D1158G	0.22
LUSC	chr3	160412500	Intron	novel		0.32
LUSC	chr3	160423569	Missense_Mutation	novel	D722H	0.15
LUSC	chr3	160433711	Missense_Mutation	novel	E1257Q	0.11
LUSC	chr3	160432418	Missense_Mutation	novel	K1145E	0.12
LUSC	chr3	160414434	Missense_Mutation	NA	D397H	0.12
OV	chr3	160402815	Missense_Mutation	NA	K153M	0.5
OV	chr3	160402805	Missense_Mutation	NA	D150N	0.36
OV	chr3	160412331	Missense_Mutation	novel	N286K	0.28
OV	chr3	160432410	Missense_Mutation	novel	I1142K	0.07
OV	chr3	160401930	Nonsense_Mutation	novel	D54*	0.15
OV	chr3	160433987	3'UTR	novel		0.18
OV	chr3	160402734	Missense_Mutation	novel	M126K	0.14
PAAD	chr3	160431680	Missense_Mutation	novel	P1051H	0.17
READ	chr3	160423518	Missense_Mutation	rs760971978	R705C	0.23
READ	chr3	160433854	3'UTR	rs772016913		0.24
READ	chr3	160420841	Missense_Mutation	NA	E653D	0.35
READ	chr3	160402764	Missense_Mutation	novel	K136I	0.53
READ	chr3	160404457	Nonsense_Mutation	rs368979205	R214*	0.42
READ	chr3	160431058	Silent	NA	E989E	0.34
READ	chr3	160423438	Missense_Mutation	rs141584099	A678V	0.32
SARC	chr3	160417757	Missense_Mutation	rs747376250	S491L	0.3
SARC	chr3	160417929	Silent	novel	L548L	0.37
SARC	chr3	160417930	Missense_Mutation	novel	P549S	0.35
SKCM	chr3	160432451	Missense_Mutation	novel	G1156R	0.25
SKCM	chr3	160404463	Missense_Mutation	NA	H216Y	0.97
SKCM	chr3	160402080	Missense_Mutation	NA	G102E	0.17
SKCM	chr3	160420880	Silent	NA	A666A	0.43
SKCM	chr3	160400853	Silent	NA	S9S	0.55
SKCM	chr3	160402683	Missense_Mutation	NA	S109F	0.33
SKCM	chr3	160414314	Intron	novel		0.49
SKCM	chr3	160432490	Missense_Mutation	novel	P1169S	0.25
SKCM	chr3	160417953	Silent	NA	K556K	0.31
SKCM	chr3	160417954	Missense_Mutation	rs200043543	E557K	0.31
SKCM	chr3	160404457	Nonsense_Mutation	rs368979205	R214*	0.13
SKCM	chr3	160420885	Missense_Mutation	novel	F668S	0.25
SKCM	chr3	160433107	Silent	NA	V1204V	0.37
SKCM	chr3	160417929	Silent	novel	L548L	0.38
SKCM	chr3	160417930	Missense_Mutation	novel	P549A	0.38
SKCM	chr3	160423824	Missense_Mutation	NA	E770G	0.1
STAD	chr3	160433751	Missense_Mutation	NA	N1270T	0.25
STAD	chr3	160423451	Silent	rs758237687	T682T	0.45
STAD	chr3	160432514	Missense_Mutation	NA	S1177G	0.39
STAD	chr3	160432293	Missense_Mutation	novel	Y1103F	0.31
STAD	chr3	160432450	Missense_Mutation	novel	L1155F	0.29
STAD	chr3	160404645	Intron	rs758766250		0.07
STAD	chr3	160402760	Frame_Shift_Ins	novel	*I137Nfs4**	0.14
STAD	chr3	160428823	Silent	NA	V892V	0.09
STAD	chr3	160430714	Missense_Mutation	NA	E971K	0.17
STAD	chr3	160433108	Missense_Mutation	NA	F1205V	0.19
STAD	chr3	160414505	Missense_Mutation	novel	K420N	0.32
STAD	chr3	160402715	Missense_Mutation	novel	S120T	0.07
STAD	chr3	160414493	Missense_Mutation	NA	K416N	0.21
STAD	chr3	160414374	Missense_Mutation	NA	N377D	0.17
STAD	chr3	160417750	Missense_Mutation	novel	S489C	0.49
STAD	chr3	160402091	Missense_Mutation	NA	K106E	0.07
STAD	chr3	160424993	Silent	NA	L818L	0.32
STAD	chr3	160404460	Missense_Mutation	NA	S215G	0.05
STAD	chr3	160419488	Missense_Mutation	NA	D601G	0.29
STAD	chr3	160431095	Missense_Mutation	novel	E1002Q	0.18
STAD	chr3	160420772	Silent	rs745744048	D630D	0.13
THCA	chr3	160416372	Frame_Shift_Ins	novel	*D465Efs7**	0.07
UCEC	chr3	160402686	Missense_Mutation	NA	C110S	0.34
UCEC	chr3	160417809	Silent	NA	I508I	0.32
UCEC	chr3	160431683	Missense_Mutation	NA	I1052S	0.36
UCEC	chr3	160433696	Nonsense_Mutation	rs753471840	R1252*	0.23
UCEC	chr3	160426189	Missense_Mutation	NA	A865V	0.3
UCEC	chr3	160433696	Nonsense_Mutation	rs753471840	R1252*	0.17
UCEC	chr3	160433823	3'UTR	novel		0.42
UCEC	chr3	160412560	Intron	novel		0.29
UCEC	chr3	160420784	Silent	rs776118825	S634S	0.41
UCEC	chr3	160433696	Nonsense_Mutation	rs753471840	R1252*	0.45
UCEC	chr3	160412534	Intron	rs188703954		0.42
UCEC	chr3	160423479	Missense_Mutation	NA	R692C	0.3
UCEC	chr3	160433696	Nonsense_Mutation	rs753471840	R1252*	0.43
UCEC	chr3	160414165	Intron	novel		0.38
UCEC	chr3	160417726	Nonsense_Mutation	rs752681997	R481*	0.42
UCEC	chr3	160419534	Silent	novel	Y616Y	0.62
UCEC	chr3	160423574	Silent	novel	Q723Q	0.06
UCEC	chr3	160431722	Missense_Mutation	rs753876897	A1065V	0.6
UCEC	chr3	160432440	Missense_Mutation	novel	M1152R	0.29
UCEC	chr3	160433200	Frame_Shift_Ins	novel	*E1239Mfs10**	0.36
UCEC	chr3	160412525	Intron	novel		0.47
UCEC	chr3	160424960	Missense_Mutation	NA	L807V	0.37
UCEC	chr3	160399384	5'Flank	novel		0.4
UCEC	chr3	160433696	Nonsense_Mutation	rs753471840	R1252*	0.43
UCEC	chr3	160402706	Missense_Mutation	NA	S117C	0.46
UCEC	chr3	160402810	Silent	novel	E151E	0.03
UCEC	chr3	160402731	Missense_Mutation	novel	S125Y	0.4
UCEC	chr3	160399426	5'Flank	novel		0.29
UCEC	chr3	160424963	Missense_Mutation	NA	R808W	0.5
UCEC	chr3	160426152	Frame_Shift_Del	NA	*K855Sfs5**	0.32
UCEC	chr3	160423518	Missense_Mutation	rs760971978	R705C	0.21
UCEC	chr3	160433857	3'UTR	novel		0.35
UCEC	chr3	160399665	5'Flank	novel		0.32
UCEC	chr3	160433691	Missense_Mutation	novel	S1250Y	0.06
UCEC	chr3	160423798	Silent	NA	G761G	0.22
UCEC	chr3	160428762	Missense_Mutation	NA	A872D	0.25
UCEC	chr3	160432462	Silent	rs142912100	A1159A	0.33
UCEC	chr3	160423480	Missense_Mutation	rs755580882	R692H	0.44
UCEC	chr3	160423581	Missense_Mutation	rs752582234	R726G	0.49
UCEC	chr3	160433035	Silent	NA	P1180P	0.47
UCEC	chr3	160404364	Missense_Mutation	NA	F183V	0.24
UCEC	chr3	160402793	Missense_Mutation	novel	I146L	0.23
UCEC	chr3	160420807	Missense_Mutation	rs763515554	Y642C	0.15
UCEC	chr3	160424972	Missense_Mutation	NA	E811K	0.26
UCEC	chr3	160428883	Silent	rs17289278	Q912Q	0.21
UCEC	chr3	160416252	Missense_Mutation	novel	V425A	0.13
UCEC	chr3	160433691	Missense_Mutation	novel	S1250Y	0.37
UCEC	chr3	160404588	Intron	novel		0.33
UCEC	chr3	160414313	Intron	novel		0.44
UCEC	chr3	160428913	Missense_Mutation	novel	K922N	0.32
UCEC	chr3	160432377	Missense_Mutation	novel	R1131K	0.13
UCEC	chr3	160431031	Splice_Site	novel	X981_splice	0.29
UCEC	chr3	160420772	Silent	rs745744048	D630D	0.4
UCEC	chr3	160404774	Intron	rs756199981		0.11
UCEC	chr3	160414105	Intron	novel		0.3
UCEC	chr3	160431695	Missense_Mutation	rs373687438	S1056L	0.44
UCEC	chr3	160433718	Missense_Mutation	rs780400107	S1259L	0.42
UCEC	chr3	160399470	5'Flank	novel		0.45
UCEC	chr3	160404645	Intron	rs758766250		0.38
UCEC	chr3	160412025	Missense_Mutation	novel	E265K	0.26
UCEC	chr3	160419502	Frame_Shift_Ins	novel	*S609Ifs18**	0.41
UCEC	chr3	160426074	Missense_Mutation	rs573812800	R827C	0.33
UCEC	chr3	160431123	Missense_Mutation	novel	A1011V	0.46
UCEC	chr3	160414478	Frame_Shift_Ins	novel	*L414Tfs9**	0.33
UCEC	chr3	160433853	3'UTR	novel		0.5
UCEC	chr3	160414517	Missense_Mutation	novel	K424N	0.4
UCEC	chr3	160402784	Missense_Mutation	NA	S143T	0.34
UCEC	chr3	160426118	Silent	NA	E841E	0.28
UCEC	chr3	160399454	5'Flank	novel		0.5
UCEC	chr3	160417809	Silent	NA	I508I	0.42
UCEC	chr3	160419542	Missense_Mutation	NA	L619S	0.44
UCEC	chr3	160420770	Missense_Mutation	novel	D630N	0.49
UCEC	chr3	160401952	Silent	novel	E59E	0.35
UCEC	chr3	160402768	Missense_Mutation	novel	I137M	0.25
UCEC	chr3	160412474	Intron	novel		0.36
UCEC	chr3	160423580	Silent	novel	T725T	0.3
UCEC	chr3	160426152	Frame_Shift_Del	NA	*K855Sfs5**	0.4
UCEC	chr3	160433734	Silent	novel	G1264G	0.36
UCEC	chr3	160404364	Missense_Mutation	NA	F183V	0.16
UCEC	chr3	160423518	Missense_Mutation	rs760971978	R705C	0.17
UCEC	chr3	160432367	Missense_Mutation	rs753663145	R1128W	0.27
UCEC	chr3	160404473	Missense_Mutation	novel	D219G	0.31
UCEC	chr3	160413603	Missense_Mutation	novel	D371H	0.34
UCEC	chr3	160431037	Silent	novel	S982S	0.39
UCEC	chr3	160402076	Missense_Mutation	novel	L101M	0.31
UCEC	chr3	160417907	Missense_Mutation	novel	I541T	0.39
UCEC	chr3	160419423	Silent	novel	L579L	0.44
UCEC	chr3	160431062	Missense_Mutation	rs747478933	R991C	0.31
UCEC	chr3	160433845	3'UTR	novel		0.43
UCEC	chr3	160404458	Missense_Mutation	rs753147258	R214Q	0.43
UCEC	chr3	160404679	Intron	novel		0.31
UCEC	chr3	160428817	Silent	novel	T890T	0.52
UCEC	chr3	160430696	Missense_Mutation	novel	L965I	0.23
UCEC	chr3	160433838	3'UTR	novel		0.36
UCEC	chr3	160412392	Missense_Mutation	rs761150992	E307K	0.14
UCEC	chr3	160433177	Frame_Shift_Del	novel	*N1229Mfs19**	0.49
UCEC	chr3	160420753	Missense_Mutation	novel	A624D	0.34
UCEC	chr3	160430686	Missense_Mutation	novel	E961D	0.31
UCEC	chr3	160431081	Missense_Mutation	NA	L997S	0.27
UCEC	chr3	160417831	Missense_Mutation	novel	A516T	0.04
UCEC	chr3	160431722	Missense_Mutation	rs753876897	A1065V	0.28
UCEC	chr3	160412550	Intron	novel		0.6
UCEC	chr3	160414419	Nonsense_Mutation	NA	Q392*	0.18
UCEC	chr3	160419502	Frame_Shift_Ins	novel	*S609Ifs18**	0.44
UCEC	chr3	160399376	5'Flank	novel		0.41
UCEC	chr3	160431143	Missense_Mutation	NA	L1018I	0.38
UCEC	chr3	160433718	Missense_Mutation	rs780400107	S1259L	0.42
UCEC	chr3	160433696	Nonsense_Mutation	rs753471840	R1252*	0.5
UCEC	chr3	160433200	Missense_Mutation	NA	F1235L	0.31
UCEC	chr3	160426152	Frame_Shift_Del	NA	*K855Sfs5**	0.48
UCEC	chr3	160417757	Missense_Mutation	rs747376250	S491L	0.13
UCEC	chr3	160433696	Nonsense_Mutation	rs753471840	R1252*	0.25
UCEC	chr3	160414378	Missense_Mutation	novel	K378T	0.43
UCEC	chr3	160433977	3'UTR	novel		0.33
UCEC	chr3	160402076	Missense_Mutation	novel	L101M	0.21
UCEC	chr3	160417901	Missense_Mutation	novel	A539V	0.16
UCEC	chr3	160428762	Missense_Mutation	novel	A872V	0.33
UCEC	chr3	160414256	Intron	novel		0.17
UCEC	chr3	160432515	Missense_Mutation	novel	S1177I	0.48
UCEC	chr3	160402722	Missense_Mutation	novel	V122G	0.4
UCEC	chr3	160404353	Missense_Mutation	novel	P179L	0.37
UCEC	chr3	160416295	Silent	rs753117042	I439I	0.33
UCEC	chr3	160424896	Silent	NA	N785N	0.29
UCEC	chr3	160414141	Intron	novel		0.42
UCEC	chr3	160431063	Missense_Mutation	rs755432637	R991H	0.31
UCS	chr3	160419487	Missense_Mutation	NA	D601H	0.64
UCS	chr3	160402736	Missense_Mutation	novel	L127I	0.36
UCS	chr3	160433187	Missense_Mutation	novel	S1231F	0.46

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRC	DEL	0.1061	0.11092
KIRP	AMP	0.3125	0.15981
PAAD	AMP	0.1087	0.16151

Survival Analysis

Cancer	P-value	Q-value
THYM	0.027	Kaplan-Meier Survival Analysis
STAD	0.039	Kaplan-Meier Survival Analysis
SARC	0.0064	Kaplan-Meier Survival Analysis
MESO	0.0024	Kaplan-Meier Survival Analysis
ACC	0.00018	Kaplan-Meier Survival Analysis
SKCM	0.0017	Kaplan-Meier Survival Analysis
PRAD	0.0022	Kaplan-Meier Survival Analysis
LUSC	0.02	Kaplan-Meier Survival Analysis
KIRP	0.0001	Kaplan-Meier Survival Analysis
COAD	0.042	Kaplan-Meier Survival Analysis
PAAD	0.0001	Kaplan-Meier Survival Analysis
PCPG	0.017	Kaplan-Meier Survival Analysis
READ	0.037	Kaplan-Meier Survival Analysis
LAML	0.037	Kaplan-Meier Survival Analysis
KICH	0.0085	Kaplan-Meier Survival Analysis
UCEC	0.00076	Kaplan-Meier Survival Analysis
LIHC	0.00048	Kaplan-Meier Survival Analysis
LUAD	0.03	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

PPI

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000113810 (Gene tree)
Gene ID: 10051
Gene Symbol: SMC4
Alias: hCAP-C|CAP-C|SMC4L1
Full Name: structural maintenance of chromosomes 4
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Plus strand
Length: 35,689 bases
Position: chr3:160,399,274-160,434,962
Accession: 14013
Summary: This gene belongs to the 'structural maintenance of chromosomes' (SMC) gene family. Members of this gene family play a role in two changes in chromosome structure during mitotic segregation of chromosomes- chromosome condensation and sister chromatid cohesion. The protein encoded by this gene is likely a subunit of the 13S condensin complex, which is involved in chromosome condensation. A pseudogene related to this gene is located on chromosome 2. [provided by RefSeq, Jun 2016]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000487747	SMC4-219	637	-	-	- (aa)	-	-
ENST00000468653	SMC4-209	1756	-	-	- (aa)	-	-
ENST00000469762	SMC4-210	3998	XM_011512312	ENSP00000417964	1263 (aa)	XP_011510614	E9PD53
ENST00000490207	SMC4-222	821	-	ENSP00000420817	180 (aa)	-	C9JJ64
ENST00000357388	SMC4-202	5471	XM_006713459	ENSP00000349961	1288 (aa)	XP_006713522	Q9NTJ3
ENST00000497203	SMC4-225	490	-	-	- (aa)	-	-
ENST00000497984	SMC4-227	563	-	-	- (aa)	-	-
ENST00000485867	SMC4-217	629	-	ENSP00000417612	157 (aa)	-	C9J9E4
ENST00000493695	SMC4-223	457	-	-	- (aa)	-	-
ENST00000344722	SMC4-201	5356	XM_011512311	ENSP00000341382	1288 (aa)	XP_011510613	Q9NTJ3
ENST00000472991	SMC4-214	582	-	ENSP00000417999	139 (aa)	-	C9J578
ENST00000485645	SMC4-216	583	-	ENSP00000420644	173 (aa)	-	C9IYK2
ENST00000486711	SMC4-218	621	-	-	- (aa)	-	-
ENST00000469858	SMC4-211	1971	-	ENSP00000418434	50 (aa)	-	F8WCB7
ENST00000488017	SMC4-220	592	-	-	- (aa)	-	-
ENST00000472282	SMC4-213	667	-	-	- (aa)	-	-
ENST00000494612	SMC4-224	622	-	-	- (aa)	-	-
ENST00000465903	SMC4-206	849	-	ENSP00000419247	170 (aa)	-	C9JWF0
ENST00000467468	SMC4-208	566	-	ENSP00000419360	119 (aa)	-	C9JVD8
ENST00000462787	SMC4-204	5033	-	ENSP00000420734	1230 (aa)	-	Q9NTJ3
ENST00000470240	SMC4-212	724	-	-	- (aa)	-	-
ENST00000484799	SMC4-215	478	-	-	- (aa)	-	-
ENST00000497311	SMC4-226	708	-	ENSP00000418820	173 (aa)	-	C9IYK2
ENST00000465563	SMC4-205	747	-	-	- (aa)	-	-
ENST00000467263	SMC4-207	401	-	-	- (aa)	-	-
ENST00000489573	SMC4-221	1553	-	ENSP00000420121	423 (aa)	-	C9JR83
ENST00000462668	SMC4-203	4235	-	-	- (aa)	-	-

Gene Model

Click here to download 's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000113810's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000113810	SMC4	99	56.934	FBgn0015391	glu	87	39.886	Drosophila_melanogaster

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000070	mitotic sister chromatid segregation	11321372.	TAS	Process
GO:0000796	condensin complex	11136719.	IDA	Component
GO:0000796	condensin complex	11850403.	TAS	Component
GO:0003697	single-stranded DNA binding	-	IEA	Function
GO:0005515	protein binding	17113138.17268547.26496610.30021884.	IPI	Function
GO:0005524	ATP binding	11136719.	TAS	Function
GO:0005634	nucleus	11850403.	TAS	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0007076	mitotic chromosome condensation	11136719.	IDA	Process
GO:0010032	meiotic chromosome condensation	-	IEA	Process
GO:0016607	nuclear speck	-	IDA	Component
GO:0045132	meiotic chromosome segregation	-	IEA	Process
GO:0046982	protein heterodimerization activity	9789013.	IPI	Function
GO:0051301	cell division	-	IEA	Process
GO:0051383	kinetochore organization	-	IEA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

PPI

Ortholog

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.