EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
27042257	Abnormal Expressions of DNA Glycosylase Genes NEIL1, NEIL2, and NEIL3 Are Associated with Somatic Mutation Loads in Human Cancer.	Oxid Med Cell Longev	2016	Shinmura K	doi: 10.1155/2016/1546392

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr4	177353425	Missense_Mutation	novel	G386E	0.27
BLCA	chr4	177335731	Missense_Mutation	NA	E108Q	0.35
BLCA	chr4	177353763	Intron	novel		0.13
BLCA	chr4	177322511	Missense_Mutation	novel	G70E	0.26
BLCA	chr4	177322488	Silent	novel	Q62Q	0.6
BLCA	chr4	177353669	Silent	NA	P467P	0.42
BLCA	chr4	177339830	Missense_Mutation	NA	I225M	0.4
BLCA	chr4	177353723	Silent	novel	S485S	0.53
BRCA	chr4	177353570	Silent	novel	K434K	0.08
BRCA	chr4	177360652	Missense_Mutation	novel	R537K	0.09
BRCA	chr4	177335718	Missense_Mutation	NA	M103I	0.27
BRCA	chr4	177353399	Silent	NA	V377V	0.21
CESC	chr4	177353316	Missense_Mutation	NA	L350I	0.36
CESC	chr4	177353566	Missense_Mutation	NA	S433F	0.14
CESC	chr4	177351446	Silent	rs138744063	S312S	0.5
CHOL	chr4	177335718	Missense_Mutation	NA	M103I	0.47
COAD	chr4	177351541	Missense_Mutation	NA	R344K	0.32	zf-RanBP
COAD	chr4	177353709	Missense_Mutation	NA	N481D	0.39
COAD	chr4	177353609	Silent	rs566894700	V447V	0.26
COAD	chr4	177353766	Intron	novel		0.72
COAD	chr4	177362387	Silent	novel	V578V	0.13
COAD	chr4	177360535	Missense_Mutation	NA	R498H	0.27
COAD	chr4	177322526	Missense_Mutation	NA	G75D	0.1
COAD	chr4	177336105	Splice_Region	novel		0.25
COAD	chr4	177335697	Silent	rs532020443	F96F	0.32
COAD	chr4	177360574	Missense_Mutation	novel	N511S	0.07
COAD	chr4	177341566	Missense_Mutation	rs762418261	R265C	0.29
ESCA	chr4	177362378	Frame_Shift_Del	NA	*F577Lfs23**	0.22
ESCA	chr4	177309880	5'UTR	rs550033836		0.17
GBM	chr4	177351488	Silent	novel	C326C	0.09
GBM	chr4	177360670	Missense_Mutation	novel	F543S	0.08
GBM	chr4	177360652	Missense_Mutation	novel	R537K	0.36
GBM	chr4	177322579	Missense_Mutation	novel	R93W	0.24
GBM	chr4	177360535	Missense_Mutation	NA	R498H	0.34
HNSC	chr4	177353860	Intron	novel		0.75
HNSC	chr4	177351456	Nonsense_Mutation	NA	K316*	0.1
HNSC	chr4	177362441	Silent	novel	G596G	0.3
HNSC	chr4	177351432	Missense_Mutation	rs376062379	H308Y	0.27
HNSC	chr4	177362392	Missense_Mutation	novel	P580H	0.17
KIRP	chr4	177322551	Silent	rs762225312	L83L	0.13
LGG	chr4	177353571	Missense_Mutation	novel	K435E	0.12
LGG	chr4	177362328	Missense_Mutation	NA	R559C	0.35
LIHC	chr4	177362422	Missense_Mutation	novel	F590S	0.44
LIHC	chr4	177362622	3'UTR	novel		0.13
LIHC	chr4	177309956	Translation_Start_Site	novel	M1?	0.06
LIHC	chr4	177335742	Silent	novel	Y111Y	0.87
LUAD	chr4	177341569	Frame_Shift_Del	novel	*F266Lfs7**	0.79
LUAD	chr4	177353731	Splice_Region	novel		0.06
LUAD	chr4	177351541	Missense_Mutation	NA	R344M	0.3	zf-RanBP
LUAD	chr4	177353475	Nonsense_Mutation	NA	E403*	0.47
LUAD	chr4	177353723	Silent	novel	S485S	0.19
LUAD	chr4	177336219	Silent	NA	R175R	0.26
LUAD	chr4	177322528	Missense_Mutation	rs34112288	V76L	0.18
LUAD	chr4	177353436	Missense_Mutation	novel	L390V	0.1
LUAD	chr4	177351439	Missense_Mutation	novel	M310T	0.28
LUAD	chr4	177339813	Missense_Mutation	novel	H220Y	0.11
LUAD	chr4	177310079	Silent	NA	L42L	0.63
LUAD	chr4	177336266	Missense_Mutation	NA	G191V	0.13
LUAD	chr4	177322462	Missense_Mutation	NA	A54S	0.15
LUSC	chr4	177335725	Missense_Mutation	novel	P106S	0.32
LUSC	chr4	177353711	Missense_Mutation	NA	N481K	0.37
LUSC	chr4	177309866	5'UTR	novel		0.25
LUSC	chr4	177351476	Silent	NA	T322T	0.55
LUSC	chr4	177335803	Missense_Mutation	novel	D132H	0.17
LUSC	chr4	177353436	Missense_Mutation	novel	L390V	0.3
LUSC	chr4	177310079	Silent	novel	L42L	0.52
LUSC	chr4	177310011	Missense_Mutation	novel	P20T	0.22
LUSC	chr4	177353722	Missense_Mutation	novel	S485F	0.13
LUSC	chr4	177336164	Missense_Mutation	novel	S157L	0.28
LUSC	chr4	177353840	Intron	novel		0.58
LUSC	chr4	177339830	Silent	NA	I225I	0.41
LUSC	chr4	177351485	Silent	NA	V325V	0.36
LUSC	chr4	177309903	5'UTR	novel		0.64
MESO	chr4	177362416	Frame_Shift_Ins	novel	*Q591Pfs47**	0.34
OV	chr4	177353655	Missense_Mutation	novel	A463T	0.12
OV	chr4	177362519	3'UTR	novel		0.37
PAAD	chr4	177339828	Missense_Mutation	rs147943632	I225V	0.22
PRAD	chr4	177353667	Missense_Mutation	rs768133212	P467T	0.07
PRAD	chr4	177353831	Intron	novel		0.43
READ	chr4	177362475	3'UTR	novel		0.2
READ	chr4	177335799	Missense_Mutation	novel	F130L	0.43
SARC	chr4	177336249	Silent	rs150006122	N185N	0.75
SKCM	chr4	177341623	Missense_Mutation	novel	P284S	0.3
SKCM	chr4	177336291	Silent	novel	L199L	0.32
SKCM	chr4	177351505	Missense_Mutation	novel	P332H	0.12	zf-RanBP
SKCM	chr4	177362592	3'UTR	novel		0.82
SKCM	chr4	177360588	Missense_Mutation	rs767326288	L516F	0.26
SKCM	chr4	177360546	Missense_Mutation	novel	P502S	0.8
SKCM	chr4	177353636	Silent	NA	E456E	0.41
SKCM	chr4	177362423	Silent	novel	F590F	0.35
SKCM	chr4	177351446	Silent	rs138744063	S312S	0.45
SKCM	chr4	177360530	Silent	rs772526444	G496G	0.79
SKCM	chr4	177336283	Missense_Mutation	NA	E197K	0.45
SKCM	chr4	177309859	5'UTR	novel		0.4
SKCM	chr4	177335726	Missense_Mutation	NA	P106L	0.33
SKCM	chr4	177322517	Missense_Mutation	novel	V72A	0.48
SKCM	chr4	177353776	Intron	novel		0.54
SKCM	chr4	177362537	3'UTR	novel		0.26
STAD	chr4	177362501	3'UTR	novel		0.29
STAD	chr4	177353766	Intron	novel		0.58
STAD	chr4	177362327	Silent	NA	K558K	0.16
STAD	chr4	177335715	Silent	novel	I102I	0.06
STAD	chr4	177335685	Splice_Region	novel		0.41
STAD	chr4	177362601	3'UTR	novel		0.43
STAD	chr4	177336202	Frame_Shift_Del	NA	*K171Nfs7**	0.25
STAD	chr4	177362378	Frame_Shift_Del	NA	*F577Lfs23**	0.14
STAD	chr4	177362329	Missense_Mutation	rs149552701	R559H	0.28
STAD	chr4	177362513	3'UTR	novel		0.09
STAD	chr4	177353766	Intron	novel		0.62
STAD	chr4	177353371	Missense_Mutation	NA	N368S	0.2
STAD	chr4	177362404	Frame_Shift_Del	novel	*K585Nfs15**	0.22
STAD	chr4	177310038	Missense_Mutation	NA	G29R	0.43
TGCT	chr4	177351435	Missense_Mutation	novel	V309I	0.61
THCA	chr4	177362317	Missense_Mutation	NA	N555S	0.2
UCEC	chr4	177341525	Missense_Mutation	rs114671957	R251H	0.53
UCEC	chr4	177360576	Missense_Mutation	rs751294884	R512C	0.58
UCEC	chr4	177353311	Missense_Mutation	NA	S348L	0.11
UCEC	chr4	177362484	3'UTR	novel		0.05
UCEC	chr4	177362484	3'UTR	novel		0.42
UCEC	chr4	177322463	Missense_Mutation	novel	A54V	0.1
UCEC	chr4	177336249	Silent	rs150006122	N185N	0.4
UCEC	chr4	177341633	Missense_Mutation	novel	V287G	0.4
UCEC	chr4	177353579	Silent	novel	T437T	0.49
UCEC	chr4	177353449	Frame_Shift_Ins	novel	S396*	0.36
UCEC	chr4	177353634	Nonsense_Mutation	novel	E456*	0.48
UCEC	chr4	177353464	Missense_Mutation	novel	S399F	0.41
UCEC	chr4	177362484	3'UTR	novel		0.18
UCEC	chr4	177339841	Missense_Mutation	NA	S229I	0.17
UCEC	chr4	177362475	3'UTR	novel		0.25
UCEC	chr4	177360531	Missense_Mutation	NA	P497T	0.29
UCEC	chr4	177335697	Silent	rs532020443	F96F	0.47
UCEC	chr4	177341513	Missense_Mutation	novel	K247T	0.22
UCEC	chr4	177335697	Silent	rs532020443	F96F	0.49
UCEC	chr4	177362329	Missense_Mutation	rs149552701	R559H	0.3
UCEC	chr4	177353611	Missense_Mutation	novel	N448S	0.21
UCEC	chr4	177362468	Nonsense_Mutation	NA	C605*	0.5
UCEC	chr4	177322577	Nonsense_Mutation	novel	L92*	0.43
UCEC	chr4	177341624	Missense_Mutation	novel	P284H	0.07
UCEC	chr4	177341626	Frame_Shift_Ins	novel	*Q285Lfs5**	0.07
UCEC	chr4	177353419	Missense_Mutation	novel	A384E	0.07
UCEC	chr4	177341525	Missense_Mutation	rs114671957	R251H	0.29
UCEC	chr4	177360535	Missense_Mutation	NA	R498H	0.34
UCEC	chr4	177362475	3'UTR	novel		0.47
UCEC	chr4	177362585	3'UTR	novel		0.33
UCEC	chr4	177322486	Nonsense_Mutation	NA	Q62*	0.34
UCEC	chr4	177335697	Silent	rs532020443	F96F	0.18
UCEC	chr4	177362378	Frame_Shift_Del	NA	*F577Lfs23**	0.31
UCEC	chr4	177362385	Missense_Mutation	NA	V578M	0.36
UCEC	chr4	177336131	Missense_Mutation	novel	R146I	0.29
UCEC	chr4	177322548	Silent	novel	E82E	0.46
UCEC	chr4	177353859	Intron	novel		0.56
UCEC	chr4	177353450	Missense_Mutation	novel	D394E	0.25
UCEC	chr4	177353461	Missense_Mutation	NA	K398T	0.34
UCEC	chr4	177362498	3'UTR	novel		0.07
UCEC	chr4	177351502	Missense_Mutation	novel	K331R	0.2	zf-RanBP
UCEC	chr4	177360535	Missense_Mutation	NA	R498H	0.24
UCEC	chr4	177339856	Missense_Mutation	novel	R234M	0.27
UCEC	chr4	177362417	Frame_Shift_Del	novel	*F590Sfs10**	0.47
UCEC	chr4	177336201	Frame_Shift_Ins	novel	*Q172Tfs8**	0.22
UCEC	chr4	177336145	Missense_Mutation	NA	K151E	0.45
UCEC	chr4	177335731	Nonsense_Mutation	novel	E108*	0.26
UCEC	chr4	177362652	3'UTR	novel		0.26
UCEC	chr4	177335687	Splice_Site	novel	X93_splice	0.35
UCEC	chr4	177353527	Missense_Mutation	novel	P420H	0.29
UCEC	chr4	177353764	Intron	novel		0.25
UCEC	chr4	177310042	Missense_Mutation	novel	S30N	0.45
UCEC	chr4	177322549	Missense_Mutation	novel	L83F	0.38
UCEC	chr4	177353527	Missense_Mutation	novel	P420H	0.38

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1556	2.13e-13
BLCA	DEL	0.326	3.0518e-13
CHOL	DEL	0.6389	6.2974e-06
DLBC	DEL	0.125	0.037264
ESCA	DEL	0.4674	0.000831
KIRC	DEL	0.1098	0.0008848
LUAD	DEL	0.2597	2.0344e-11
MESO	DEL	0.3793	0.10007
PAAD	DEL	0.1196	0.027407
PCPG	DEL	0.0802	0.003794
READ	DEL	0.3455	4.2375e-05
THCA	DEL	0.008	0.065321

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0029	Kaplan-Meier Survival Analysis
STAD	0.043	Kaplan-Meier Survival Analysis
MESO	0.00012	Kaplan-Meier Survival Analysis
ACC	0.0001	Kaplan-Meier Survival Analysis
KIRP	0.0023	Kaplan-Meier Survival Analysis
PAAD	0.00014	Kaplan-Meier Survival Analysis
BLCA	0.05	Kaplan-Meier Survival Analysis
KICH	0.0077	Kaplan-Meier Survival Analysis
UCEC	0.0019	Kaplan-Meier Survival Analysis
LIHC	0.0001	Kaplan-Meier Survival Analysis
CHOL	0.016	Kaplan-Meier Survival Analysis
LUAD	0.0001	Kaplan-Meier Survival Analysis
UVM	0.0027	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Pathway

Phenotype

PPI

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000109674 (Gene tree)
Gene ID: 55247
Gene Symbol: NEIL3
Alias: FLJ10858|hFPG2|FPG2|hNEI3|ZGRF3
Full Name: nei like DNA glycosylase 3
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Plus strand
Length: 53,108 bases
Position: chr4:177,309,836-177,362,943
Accession: 24573
Summary: NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000264596	zf-RanBP	PF00641.18	5.3e-06	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000264596	NEIL3-201	2408	XM_017008360	ENSP00000264596	605 (aa)	XP_016863849	Q8TAT5
ENST00000513321	NEIL3-202	1528	-	ENSP00000424735	63 (aa)	-	D6RAV1

Gene Model

Click here to download ENSG00000109674's gene model file

Pathway

Pathway ID	Pathway Name	Source
hsa03410	Base excision repair	KEGG

Phenotype

ensgID	Trait	pValue	Pubmed ID
ENSG00000109674	Subcutaneous Fat	2.45388273298897E-5	17903300
ENSG00000109674	Subcutaneous Fat	2.87687391937741E-5	17903300
ENSG00000109674	Abdominal Fat	1.93592959196742E-6	17903300
ENSG00000109674	Abdominal Fat	2.13718218899928E-6	17903300
ENSG00000109674	Intra-Abdominal Fat	3.05938989166865E-5	17903300
ENSG00000109674	Body Weights and Measures	3.53412189277869E-5	17903300
ENSG00000109674	Heart Rate	9.1026905905563E-7	17903306
ENSG00000109674	Heart Rate	6.88670489997163E-6	17903306
ENSG00000109674	Glucose	9.356e-005	-
ENSG00000109674	Platelet Function Tests	2.1314100E-005	-
ENSG00000109674	Platelet Function Tests	2.1314100E-005	-
ENSG00000109674	Selenium	3E-7	23698163
ENSG00000109674	Heart Rate	7E-6	17903306

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000109674's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000109674	NEIL3	100	51.064	ENSACIG00000002265	neil3	100	51.064	Amphilophus_citrinellus
ENSG00000109674	NEIL3	100	51.774	ENSATEG00000004193	neil3	100	51.774	Anabas_testudineus
ENSG00000109674	NEIL3	100	84.488	ENSANAG00000026464	NEIL3	100	84.488	Aotus_nancymaae
ENSG00000109674	NEIL3	100	51.452	ENSACLG00000011270	neil3	100	52.389	Astatotilapia_calliptera
ENSG00000109674	NEIL3	100	78.418	ENSBTAG00000005825	NEIL3	100	78.418	Bos_taurus
ENSG00000109674	NEIL3	100	90.759	ENSCJAG00000005464	NEIL3	100	90.759	Callithrix_jacchus
ENSG00000109674	NEIL3	100	78.089	ENSCHIG00000009157	NEIL3	100	78.089	Capra_hircus
ENSG00000109674	NEIL3	100	81.188	ENSTSYG00000014680	NEIL3	100	81.188	Carlito_syrichta
ENSG00000109674	NEIL3	85	77.973	ENSCAPG00000006333	NEIL3	98	77.973	Cavia_aperea
ENSG00000109674	NEIL3	100	78.254	ENSCPOG00000003297	NEIL3	100	78.254	Cavia_porcellus
ENSG00000109674	NEIL3	100	91.419	ENSCCAG00000018838	NEIL3	100	91.419	Cebus_capucinus
ENSG00000109674	NEIL3	100	77.265	ENSCLAG00000015661	NEIL3	100	77.265	Chinchilla_lanigera
ENSG00000109674	NEIL3	100	90.083	ENSCSAG00000003064	NEIL3	100	90.083	Chlorocebus_sabaeus
ENSG00000109674	NEIL3	77	89.831	ENSCHOG00000008101	NEIL3	77	89.831	Choloepus_hoffmanni
ENSG00000109674	NEIL3	100	91.074	ENSCANG00000043622	NEIL3	100	91.074	Colobus_angolensis_palliatus
ENSG00000109674	NEIL3	100	52.335	ENSCSEG00000003828	neil3	99	52.335	Cynoglossus_semilaevis
ENSG00000109674	NEIL3	100	51.060	ENSDARG00000020079	neil3	100	51.060	Danio_rerio
ENSG00000109674	NEIL3	86	80.614	ENSDNOG00000012236	NEIL3	100	80.614	Dasypus_novemcinctus
ENSG00000109674	NEIL3	100	80.395	ENSEASG00005022272	NEIL3	100	80.395	Equus_asinus_asinus
ENSG00000109674	NEIL3	100	79.538	ENSECAG00000009121	NEIL3	100	79.901	Equus_caballus
ENSG00000109674	NEIL3	75	70.485	ENSEEUG00000010848	NEIL3	100	70.485	Erinaceus_europaeus
ENSG00000109674	NEIL3	100	78.089	ENSFCAG00000004956	NEIL3	100	78.089	Felis_catus
ENSG00000109674	NEIL3	100	50.647	ENSHBUG00000023848	neil3	100	50.647	Haplochromis_burtoni
ENSG00000109674	NEIL3	86	79.271	ENSHGLG00000006643	NEIL3	100	79.271	Heterocephalus_glaber_female
ENSG00000109674	NEIL3	86	79.271	ENSHGLG00100006959	NEIL3	100	79.271	Heterocephalus_glaber_male
ENSG00000109674	NEIL3	100	80.066	ENSSTOG00000016245	NEIL3	100	80.066	Ictidomys_tridecemlineatus
ENSG00000109674	NEIL3	63	56.701	ENSLACG00000000308	NEIL3	99	56.701	Latimeria_chalumnae
ENSG00000109674	NEIL3	100	92.066	ENSMFAG00000002547	NEIL3	100	92.066	Macaca_fascicularis
ENSG00000109674	NEIL3	100	91.901	ENSMMUG00000007394	NEIL3	100	91.901	Macaca_mulatta
ENSG00000109674	NEIL3	100	91.901	ENSMNEG00000036177	NEIL3	100	91.901	Macaca_nemestrina
ENSG00000109674	NEIL3	100	51.967	ENSMAMG00000017052	neil3	100	51.864	Mastacembelus_armatus
ENSG00000109674	NEIL3	100	51.613	ENSMZEG00005001680	neil3	100	51.613	Maylandia_zebra
ENSG00000109674	NEIL3	90	63.815	ENSMODG00000003813	NEIL3	99	63.815	Monodelphis_domestica
ENSG00000109674	NEIL3	100	74.092	MGP_CAROLIEiJ_G0031052	Neil3	100	74.092	Mus_caroli
ENSG00000109674	NEIL3	100	73.927	ENSMUSG00000039396	Neil3	100	73.927	Mus_musculus
ENSG00000109674	NEIL3	100	73.762	MGP_PahariEiJ_G0021518	Neil3	100	73.762	Mus_pahari
ENSG00000109674	NEIL3	100	74.257	MGP_SPRETEiJ_G0032167	Neil3	100	74.257	Mus_spretus
ENSG00000109674	NEIL3	100	50.330	ENSNBRG00000013229	neil3	100	50.330	Neolamprologus_brichardi
ENSG00000109674	NEIL3	100	94.554	ENSNLEG00000016818	NEIL3	100	94.554	Nomascus_leucogenys
ENSG00000109674	NEIL3	100	76.606	ENSODEG00000004102	NEIL3	100	76.606	Octodon_degus
ENSG00000109674	NEIL3	100	51.133	ENSONIG00000001176	neil3	100	51.133	Oreochromis_niloticus
ENSG00000109674	NEIL3	99	80.167	ENSOCUG00000001040	NEIL3	99	80.167	Oryctolagus_cuniculus
ENSG00000109674	NEIL3	100	48.544	ENSOMEG00000014798	neil3	100	48.544	Oryzias_melastigma
ENSG00000109674	NEIL3	100	81.219	ENSOGAG00000012624	NEIL3	100	81.219	Otolemur_garnettii
ENSG00000109674	NEIL3	96	76.936	ENSOARG00000006852	NEIL3	100	79.459	Ovis_aries
ENSG00000109674	NEIL3	100	96.370	ENSPPAG00000035318	NEIL3	100	96.370	Pan_paniscus
ENSG00000109674	NEIL3	100	78.418	ENSPPRG00000003958	NEIL3	100	78.418	Panthera_pardus
ENSG00000109674	NEIL3	100	78.913	ENSPTIG00000012966	NEIL3	100	78.913	Panthera_tigris_altaica
ENSG00000109674	NEIL3	100	97.525	ENSPTRG00000016617	NEIL3	100	97.525	Pan_troglodytes
ENSG00000109674	NEIL3	100	91.901	ENSPANG00000014727	NEIL3	100	91.901	Papio_anubis
ENSG00000109674	NEIL3	100	50.243	ENSPFOG00000018858	neil3	100	50.243	Poecilia_formosa
ENSG00000109674	NEIL3	100	49.919	ENSPLAG00000010685	neil3	100	49.919	Poecilia_latipinna
ENSG00000109674	NEIL3	100	50.243	ENSPMEG00000013971	neil3	100	50.243	Poecilia_mexicana
ENSG00000109674	NEIL3	100	50.247	ENSPREG00000009841	neil3	100	50.247	Poecilia_reticulata
ENSG00000109674	NEIL3	68	83.051	ENSPCAG00000006386	NEIL3	81	83.051	Procavia_capensis
ENSG00000109674	NEIL3	77	90.756	ENSPCOG00000010888	NEIL3	97	90.756	Propithecus_coquereli
ENSG00000109674	NEIL3	99	77.483	ENSPVAG00000002255	NEIL3	99	77.483	Pteropus_vampyrus
ENSG00000109674	NEIL3	100	51.303	ENSPNYG00000021276	neil3	100	51.303	Pundamilia_nyererei
ENSG00000109674	NEIL3	98	47.892	ENSPNAG00000019983	neil3	100	47.892	Pygocentrus_nattereri
ENSG00000109674	NEIL3	100	72.607	ENSRNOG00000011688	Neil3	100	72.607	Rattus_norvegicus
ENSG00000109674	NEIL3	100	90.413	ENSRBIG00000023002	NEIL3	100	90.413	Rhinopithecus_bieti
ENSG00000109674	NEIL3	100	90.248	ENSRROG00000000069	NEIL3	100	90.248	Rhinopithecus_roxellana
ENSG00000109674	NEIL3	100	90.759	ENSSBOG00000032601	NEIL3	100	90.759	Saimiri_boliviensis_boliviensis
ENSG00000109674	NEIL3	100	67.105	ENSSHAG00000007680	NEIL3	100	67.105	Sarcophilus_harrisii
ENSG00000109674	NEIL3	100	51.442	ENSSMAG00000009621	neil3	100	51.763	Scophthalmus_maximus
ENSG00000109674	NEIL3	100	78.418	ENSSSCG00000015771	NEIL3	100	78.418	Sus_scrofa
ENSG00000109674	NEIL3	100	78.254	ENSTTRG00000013224	NEIL3	100	78.254	Tursiops_truncatus
ENSG00000109674	NEIL3	100	69.737	ENSVPAG00000005020	NEIL3	100	69.737	Vicugna_pacos
ENSG00000109674	NEIL3	90	48.087	ENSXCOG00000014831	neil3	99	48.087	Xiphophorus_couchianus
ENSG00000109674	NEIL3	100	49.838	ENSXMAG00000028638	neil3	100	49.838	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000405	bubble DNA binding	-	ISS	Function
GO:0003684	damaged DNA binding	-	IEA	Function
GO:0003690	double-stranded DNA binding	-	ISS	Function
GO:0003697	single-stranded DNA binding	19170771.	IDA	Function
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	21873635.	IBA	Function
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	19170771.	IDA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	12433996.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0006284	base-excision repair	21873635.	IBA	Process
GO:0006284	base-excision repair	23755964.	IDA	Process
GO:0006284	base-excision repair	-	ISS	Process
GO:0006289	nucleotide-excision repair	-	IEA	Process
GO:0008270	zinc ion binding	-	IEA	Function
GO:0019104	DNA N-glycosylase activity	21873635.	IBA	Function
GO:0019104	DNA N-glycosylase activity	23755964.	IDA	Function
GO:0019104	DNA N-glycosylase activity	-	ISS	Function
GO:0140078	class I DNA-(apurinic or apyrimidinic site) endonuclease activity	-	IEA	Function

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Input Drug :

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Pathway

Phenotype

PPI

Ortholog

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.