EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
27256982	Altered splicing leads to reduced activation of CPEB3 in high-grade gliomas.	Oncotarget	2016 Jul 5	Skubal M	doi: 10.18632/oncotarget.9735.
27515006	MicroRNA and target gene expression based clustering of oral cancer, precancer and normal tissues.	Gene	2016 Nov 15	Roy R	doi: 10.1016/j.gene.2016.08.011

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr10	92239618	Frame_Shift_Del	novel	*S241Rfs77**	0.6
BLCA	chr10	92081388	Nonsense_Mutation	novel	Q601*	0.31
BLCA	chr10	92145004	Missense_Mutation	rs754639698	R435Q	0.26
BLCA	chr10	92192566	Missense_Mutation	NA	T359S	0.23
BLCA	chr10	92111171	Nonsense_Mutation	novel	E493*	0.25	RRM_1
BRCA	chr10	92192546	Missense_Mutation	NA	G366R	0.67
BRCA	chr10	92049921	3'UTR	novel		0.29
BRCA	chr10	92049803	3'UTR	novel		0.28
BRCA	chr10	92052416	Silent	rs148506777	L631L	0.31
BRCA	chr10	92240332	Missense_Mutation	novel	M7L	0.15
BRCA	chr10	92049834	3'UTR	novel		0.28
BRCA	chr10	92145110	Intron	novel		0.09
BRCA	chr10	92111178	Silent	NA	L490L	0.24
CESC	chr10	92049093	3'Flank	novel		0.48
CESC	chr10	92048835	3'Flank	novel		0.4
CESC	chr10	92049460	3'Flank	novel		0.27
CESC	chr10	92050485	3'UTR	novel		0.33
CESC	chr10	92051518	3'UTR	novel		0.26
CESC	chr10	92051758	3'UTR	novel		0.21
CESC	chr10	92051719	3'UTR	novel		0.27
CESC	chr10	92091864	Missense_Mutation	novel	I551M	0.09
CESC	chr10	92049766	3'UTR	novel		0.73
CESC	chr10	92239706	Missense_Mutation	novel	I215M	0.19
COAD	chr10	92091848	Missense_Mutation	NA	P557T	0.41
COAD	chr10	92239422	Missense_Mutation	NA	A310V	0.35
COAD	chr10	92192598	Silent	NA	S348S	0.22
COAD	chr10	92091835	Missense_Mutation	novel	R561Q	0.04
COAD	chr10	92052267	Missense_Mutation	novel	P681L	0.15
COAD	chr10	92081477	Missense_Mutation	NA	R571H	0.53
COAD	chr10	92239989	Missense_Mutation	novel	D121G	0.11
COAD	chr10	92240242	Missense_Mutation	novel	S37P	0.16
COAD	chr10	92052110	3'UTR	novel		0.6
COAD	chr10	92145023	Missense_Mutation	rs143773953	R429C	0.36
COAD	chr10	92192599	Missense_Mutation	rs747888308	S348L	0.26
ESCA	chr10	92050906	3'UTR	novel		0.44
ESCA	chr10	92049851	3'UTR	novel		0.28
HNSC	chr10	92192633	Missense_Mutation	rs745558291	R337W	0.16
HNSC	chr10	92143098	Missense_Mutation	rs767383587	R462C	0.36	RRM_1
HNSC	chr10	92180993	Missense_Mutation	novel	P398S	0.16
KIRC	chr10	92180962	Frame_Shift_Ins	novel	*N408Kfs6**	0.35
KIRP	chr10	92239901	Silent	NA	T150T	0.31
KIRP	chr10	92091892	Missense_Mutation	novel	S542F	0.47
KIRP	chr10	92052322	Missense_Mutation	NA	C663R	0.43
LGG	chr10	92181011	Missense_Mutation	novel	G392R	0.16
LGG	chr10	92239871	Silent	novel	T160T	0.41
LIHC	chr10	92143080	Missense_Mutation	rs773585852	V468I	0.11	RRM_1
LIHC	chr10	92239840	Missense_Mutation	novel	P171S	0.53
LIHC	chr10	92052223	Missense_Mutation	rs761798097	R696C	0.58
LIHC	chr10	92239480	Missense_Mutation	novel	P291S	0.21
LIHC	chr10	92145068	Missense_Mutation	novel	S414C	0.32
LUAD	chr10	92181016	Missense_Mutation	novel	R390P	0.48
LUAD	chr10	92052110	3'UTR	novel		0.33
LUAD	chr10	92143089	Missense_Mutation	novel	G465R	0.14	RRM_1
LUAD	chr10	92144996	Missense_Mutation	NA	R438S	0.36
LUSC	chr10	92239360	Missense_Mutation	NA	L331V	0.12
LUSC	chr10	92081361	Missense_Mutation	rs770947312	A610T	0.76
OV	chr10	92143080	Missense_Mutation	novel	V468L	0.04	RRM_1
OV	chr10	92081477	Missense_Mutation	NA	R571H	0.45
PAAD	chr10	92239940	Missense_Mutation	novel	Q137H	0.09
PRAD	chr10	92239990	Missense_Mutation	NA	D121H	0.4
READ	chr10	92192557	Missense_Mutation	novel	E362A	0.47
READ	chr10	92240348	Translation_Start_Site	novel	M1?	0.33
SARC	chr10	92143080	Missense_Mutation	novel	V468L	0.3	RRM_1
SKCM	chr10	92091836	Nonsense_Mutation	novel	R561*	0.43
SKCM	chr10	92081433	Missense_Mutation	NA	E586K	0.19
SKCM	chr10	92091910	Missense_Mutation	NA	D536G	0.35
SKCM	chr10	92181001	Missense_Mutation	NA	F395S	0.23
SKCM	chr10	92192498	Missense_Mutation	rs774076302	M382V	0.21
SKCM	chr10	92091924	Silent	NA	N531N	0.63
SKCM	chr10	92091935	Nonsense_Mutation	NA	R528*	0.26
STAD	chr10	92081404	Silent	rs778665459	R595R	0.32
STAD	chr10	92181002	Missense_Mutation	NA	F395L	0.18
STAD	chr10	92239961	Silent	NA	V130V	0.14
THYM	chr10	92050083	3'UTR	novel		0.06
UCEC	chr10	92051192	3'UTR	novel		0.25
UCEC	chr10	92051239	3'UTR	novel		0.11
UCEC	chr10	92052000	3'UTR	novel		0.52
UCEC	chr10	92239469	Silent	novel	K294K	0.09
UCEC	chr10	92091935	Nonsense_Mutation	NA	R528*	0.05
UCEC	chr10	92145022	Missense_Mutation	rs201096601	R429H	0.33
UCEC	chr10	92239982	Silent	NA	F123F	0.19
UCEC	chr10	92051915	3'UTR	novel		0.34
UCEC	chr10	92143097	Missense_Mutation	novel	R462H	0.38	RRM_1
UCEC	chr10	92111129	Nonsense_Mutation	novel	E507*	0.42
UCEC	chr10	92051592	3'UTR	novel		0.29
UCEC	chr10	92049996	3'UTR	novel		0.59
UCEC	chr10	92048929	3'Flank	novel		0.28
UCEC	chr10	92049517	3'Flank	novel		0.42
UCEC	chr10	92051117	3'UTR	novel		0.33
UCEC	chr10	92111121	Silent	novel	G509G	0.17
UCEC	chr10	92048716	3'Flank	novel		0.27
UCEC	chr10	92049520	3'Flank	novel		0.62
UCEC	chr10	92050158	3'UTR	novel		0.57
UCEC	chr10	92050728	3'UTR	novel		0.26
UCEC	chr10	92050895	3'UTR	novel		0.33
UCEC	chr10	92051316	3'UTR	novel		0.51
UCEC	chr10	92052104	3'UTR	rs562880416		0.52
UCEC	chr10	92081358	Missense_Mutation	novel	R611C	0.44
UCEC	chr10	92239558	Missense_Mutation	rs761634354	G265S	0.33
UCEC	chr10	92051395	3'UTR	novel		0.13
UCEC	chr10	92240163	Frame_Shift_Del	rs751359395	*P63Rfs19**	0.18
UCEC	chr10	92049058	3'Flank	novel		0.5
UCEC	chr10	92049526	3'Flank	novel		0.3
UCEC	chr10	92049391	3'Flank	novel		0.44
UCEC	chr10	92050412	3'UTR	novel		0.46
UCEC	chr10	92050106	3'UTR	novel		0.52
UCEC	chr10	92180984	Missense_Mutation	novel	D401Y	0.13
UCEC	chr10	92180984	Missense_Mutation	novel	D401Y	0.27
UCEC	chr10	92240163	Frame_Shift_Del	rs751359395	*P63Rfs19**	0.42
UCEC	chr10	92144995	Missense_Mutation	rs749351946	R438H	0.41
UCEC	chr10	92050151	3'UTR	novel		0.38
UCEC	chr10	92051117	3'UTR	novel		0.36
UCEC	chr10	92050916	3'UTR	novel		0.29
UCEC	chr10	92239382	Frame_Shift_Ins	NA	*R324Pfs4**	0.55
UCEC	chr10	92049280	3'Flank	novel		0.33
UCEC	chr10	92049746	3'UTR	novel		0.32
UCEC	chr10	92049096	3'Flank	novel		0.41
UCEC	chr10	92049526	3'Flank	novel		0.21
UCEC	chr10	92050794	3'UTR	novel		0.36
UCEC	chr10	92052022	3'UTR	novel		0.45
UCEC	chr10	92050967	3'UTR	novel		0.21
UCEC	chr10	92051965	3'UTR	novel		0.13
UCEC	chr10	92050217	3'UTR	novel		0.52
UCEC	chr10	92049526	3'Flank	novel		0.29
UCEC	chr10	92051244	3'UTR	novel		0.62
UCEC	chr10	92081481	Missense_Mutation	NA	D570N	0.19
UCEC	chr10	92049234	3'Flank	novel		0.4
UCEC	chr10	92143102	Silent	novel	S460S	0.2
UCEC	chr10	92239549	Missense_Mutation	novel	P268S	0.11
UVM	chr10	92081501	Missense_Mutation	novel	V563A	0.47

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1	0.19593
CHOL	DEL	0.1667	0.048655
MESO	DEL	0.2644	0.00015289
PAAD	DEL	0.125	0.169
READ	DEL	0.2485	0.014135
THCA	DEL	0.02	0.011063
THYM	DEL	0.0325	0.10563
UCS	DEL	0.3393	0.1218

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00037	Kaplan-Meier Survival Analysis
SARC	0.014	Kaplan-Meier Survival Analysis
MESO	0.00015	Kaplan-Meier Survival Analysis
HNSC	0.0012	Kaplan-Meier Survival Analysis
SKCM	0.00013	Kaplan-Meier Survival Analysis
LUSC	0.05	Kaplan-Meier Survival Analysis
KIRP	0.002	Kaplan-Meier Survival Analysis
PAAD	0.043	Kaplan-Meier Survival Analysis
CESC	0.03	Kaplan-Meier Survival Analysis
LAML	0.047	Kaplan-Meier Survival Analysis
KICH	0.035	Kaplan-Meier Survival Analysis
LIHC	0.00011	Kaplan-Meier Survival Analysis
LUAD	0.0023	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000107864 (Gene tree)
Gene ID: 22849
Gene Symbol: CPEB3
Alias: KIAA0940
Full Name: cytoplasmic polyadenylation element binding protein 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 244,427 bases
Position: chr10:92,046,692-92,291,118
Accession: 21746
RBP type: canonical RBP
Summary: (Cytoplasmic Polyadenylation Element Binding Protein 3) is a Protein Coding gene. Among its related pathways are Oocyte meiosis. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is CPEB2.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000398310	RRM_1	PF00076.22	6.2e-11	1	1
ENSP00000265997	RRM_1	PF00076.22	6.5e-11	1	1
ENSP00000482128	RRM_1	PF00076.22	6.5e-11	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
22730302	NMDAR signaling facilitates the IPO5-mediated nuclear import of CPEB3.	Nucleic Acids Res	2012 Sep 1	Chao HW	-
17923234	Analysis of mRNA translation in cultured hippocampal neurons.	Methods Enzymol	2007	Huang YS	-
24343026	Identifying RNA-binding residues based on evolutionary conserved structural and energetic features.	Nucleic Acids Res	2014 Feb	Chen YC	doi: 10.1093/nar/gkt1299
22711986	Calpain 2 activated through N-methyl-D-aspartic acid receptor signaling cleaves CPEB3 and abrogates CPEB3-repressed translation in neurons.	Mol Cell Biol	2012 Aug	Wang CF	doi: 10.1128/MCB.00296-12
21336257	Anti-proliferative protein Tob negatively regulates CPEB3 target by recruiting Caf1 deadenylase.	EMBO J	2011 Apr 6	Hosoda N	doi: 10.1038/emboj.2011.37
24155305	Deletion of CPEB3 enhances hippocampus-dependent memory via increasing expressions of PSD95 and NMDA receptors.	J Neurosci	2013 Oct 23	Chao HW	doi: 10.1523/JNEUROSCI.3043-13.2013.
25404896	Elevated activation of CaMKIIα in the CPEB3-knockout hippocampus impairs a specific form of NMDAR-dependent synaptic depotentiation.	Front Cell Neurosci	2014 Nov 3	Huang WH	doi: 10.3389/fncel.2014.00367
23776146	Specificity factors in cytoplasmic polyadenylation.	Wiley Interdiscip Rev RNA	2013 Jul-Aug	Charlesworth A	doi: 10.1002/wrna.1171.
26915043	CPEB3 Deficiency Elevates TRPV1 Expression in Dorsal Root Ganglia Neurons to Potentiate Thermosensation.	PLoS One	2016 Feb 25	Fong SW	doi: 10.1371/journal.pone.0148491
17024188	CPEB3 and CPEB4 in neurons: analysis of RNA-binding specificity and translational control of AMPA receptor GluR2 mRNA.	EMBO J	2006 Oct 18	Huang YS	-
20639532	A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons.	Nucleic Acids Res	2010 Nov	Peng SC	doi: 10.1093/nar/gkq634
25066254	Novel RNA recognition motif domain in the cytoplasmic polyadenylation element binding protein 3.	Proteins	2014 Oct	Tsuda K	doi: 10.1002/prot.24651
24990518	Selective inhibition of miR-92 in hippocampal neurons alters contextual fear memory.	Hippocampus	2014 Dec	Vetere G	doi: 10.1002/hipo.22326
25842244	NH125 reduces the level of CPEB3, an RNA binding protein, to promote synaptic GluA2 expression.	Neuropharmacology	2016 Feb	Bender CL	doi: 10.1016/j.neuropharm.2015.03.017
27681423	Topological Regulation of Synaptic AMPA Receptor Expression by the RNA-Binding Protein CPEB3.	Cell Rep	2016 Sep 27	Savtchouk I	doi: 10.1016/j.celrep.2016.08.094.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000412050	CPEB3-202	7664	XM_005269630	ENSP00000398310	684 (aa)	XP_005269687	Q8NE35
ENST00000614585	CPEB3-203	5789	XM_006717714	ENSP00000482128	698 (aa)	XP_006717777	Q8NE35
ENST00000265997	CPEB3-201	4851	XM_006717715	ENSP00000265997	698 (aa)	XP_006717778	Q8NE35

Gene Model

Click here to download ENSG00000107864's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04114	Oocyte meiosis	KEGG
hsa04914	Progesterone-mediated oocyte maturation	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000107864	Survival	7.63296005423033E-25	17903295
ENSG00000107864	Muscle, Skeletal	2.2130000E-005	-
ENSG00000107864	Muscle, Skeletal	2.4470000E-005	-
ENSG00000107864	Rotator Cuff	2.1830000E-005	-
ENSG00000107864	Rotator Cuff	2.4490000E-005	-
ENSG00000107864	Calcium	4.4010000E-005	-
ENSG00000107864	Platelet Function Tests	1.6800000E-006	-
ENSG00000107864	Platelet Function Tests	1.6800000E-006	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000107864	rs12252682	10	92050985	C	Fear of minor pain	28701861	unit decrease	2.45	EFO_0008340
ENSG00000107864	rs1776209	10	92051115	?	Body mass index	30595370			EFO_0004340
ENSG00000107864	rs72807246	10	92172529	G	Breast cancer	29059683	[0.025-0.061] unit decrease	0.0429	EFO_0000305
ENSG00000107864	rs61875203	10	92129053	T	Chronotype	30696823		1.0262383	EFO_0008328

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000107864's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000107864	CPEB3	65	79.379	ENSG00000137449	CPEB2	100	98.802
ENSG00000107864	CPEB3	100	58.650	ENSG00000113742	CPEB4	100	85.965

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000107864	CPEB3	100	73.596	ENSAPOG00000003625	cpeb3	100	73.082	Acanthochromis_polyacanthus
ENSG00000107864	CPEB3	100	86.853	ENSAMEG00000014204	CPEB3	100	86.434	Ailuropoda_melanoleuca
ENSG00000107864	CPEB3	100	72.361	ENSACIG00000001933	cpeb3	100	71.646	Amphilophus_citrinellus
ENSG00000107864	CPEB3	100	74.891	ENSAOCG00000015423	cpeb3	100	74.133	Amphiprion_ocellaris
ENSG00000107864	CPEB3	100	74.709	ENSATEG00000010649	cpeb3	100	74.096	Anabas_testudineus
ENSG00000107864	CPEB3	100	81.590	ENSACAG00000006335	CPEB3	100	82.033	Anolis_carolinensis
ENSG00000107864	CPEB3	100	97.167	ENSANAG00000037406	CPEB3	100	97.167	Aotus_nancymaae
ENSG00000107864	CPEB3	100	74.165	ENSACLG00000018590	cpeb3	89	73.094	Astatotilapia_calliptera
ENSG00000107864	CPEB3	100	97.568	ENSBTAG00000015450	CPEB3	100	97.568	Bos_taurus
ENSG00000107864	CPEB3	100	97.179	ENSCJAG00000008495	CPEB3	100	97.179	Callithrix_jacchus
ENSG00000107864	CPEB3	100	97.668	ENSCAFG00000007423	CPEB3	100	97.668	Canis_familiaris
ENSG00000107864	CPEB3	100	95.391	ENSCAFG00020001981	CPEB3	100	95.391	Canis_lupus_dingo
ENSG00000107864	CPEB3	100	97.714	ENSCHIG00000017337	CPEB3	100	97.714	Capra_hircus
ENSG00000107864	CPEB3	83	100.000	ENSTSYG00000003928	CPEB3	83	100.000	Carlito_syrichta
ENSG00000107864	CPEB3	100	98.009	ENSCCAG00000033267	CPEB3	100	98.009	Cebus_capucinus
ENSG00000107864	CPEB3	100	98.694	ENSCATG00000038447	CPEB3	100	98.694	Cercocebus_atys
ENSG00000107864	CPEB3	69	97.358	ENSCLAG00000011817	CPEB3	100	97.358	Chinchilla_lanigera
ENSG00000107864	CPEB3	100	98.837	ENSCSAG00000006579	CPEB3	100	98.837	Chlorocebus_sabaeus
ENSG00000107864	CPEB3	52	90.083	ENSCHOG00000000272	-	100	90.083	Choloepus_hoffmanni
ENSG00000107864	CPEB3	100	83.780	ENSCPBG00000023779	CPEB3	100	83.216	Chrysemys_picta_bellii
ENSG00000107864	CPEB3	100	98.981	ENSCANG00000040306	CPEB3	100	98.981	Colobus_angolensis_palliatus
ENSG00000107864	CPEB3	100	97.290	ENSCGRG00001003846	Cpeb3	100	97.290	Cricetulus_griseus_chok1gshd
ENSG00000107864	CPEB3	58	97.349	ENSCGRG00000002839	Cpeb3	100	97.349	Cricetulus_griseus_crigri
ENSG00000107864	CPEB3	89	72.446	ENSCSEG00000008423	cpeb3	100	72.025	Cynoglossus_semilaevis
ENSG00000107864	CPEB3	100	71.533	ENSCVAG00000005998	cpeb3	100	69.956	Cyprinodon_variegatus
ENSG00000107864	CPEB3	100	66.906	ENSDARG00000060103	cpeb3	100	66.619	Danio_rerio
ENSG00000107864	CPEB3	100	90.442	ENSDNOG00000048639	CPEB3	100	90.300	Dasypus_novemcinctus
ENSG00000107864	CPEB3	89	99.779	ENSDORG00000028940	Cpeb3	88	99.779	Dipodomys_ordii
ENSG00000107864	CPEB3	100	89.971	ENSETEG00000000111	CPEB3	100	89.398	Echinops_telfairi
ENSG00000107864	CPEB3	90	61.120	ENSEBUG00000010745	cpeb3	79	61.631	Eptatretus_burgeri
ENSG00000107864	CPEB3	100	96.479	ENSEASG00005011095	CPEB3	100	96.479	Equus_asinus_asinus
ENSG00000107864	CPEB3	100	96.756	ENSECAG00000000077	CPEB3	100	96.756	Equus_caballus
ENSG00000107864	CPEB3	100	73.737	ENSELUG00000019251	cpeb3	100	74.277	Esox_lucius
ENSG00000107864	CPEB3	100	97.956	ENSFCAG00000032380	CPEB3	100	97.956	Felis_catus
ENSG00000107864	CPEB3	100	85.014	ENSFALG00000007952	CPEB3	87	84.150	Ficedula_albicollis
ENSG00000107864	CPEB3	87	100.000	ENSFDAG00000016459	CPEB3	88	100.000	Fukomys_damarensis
ENSG00000107864	CPEB3	100	70.563	ENSFHEG00000021371	cpeb3	100	67.832	Fundulus_heteroclitus
ENSG00000107864	CPEB3	89	70.983	ENSGMOG00000008307	cpeb3	99	70.047	Gadus_morhua
ENSG00000107864	CPEB3	100	84.908	ENSGALG00000006912	CPEB3	100	84.344	Gallus_gallus
ENSG00000107864	CPEB3	99	71.208	ENSGACG00000002944	cpeb3	99	70.810	Gasterosteus_aculeatus
ENSG00000107864	CPEB3	100	83.357	ENSGAGG00000008528	CPEB3	100	82.511	Gopherus_agassizii
ENSG00000107864	CPEB3	100	98.446	ENSGGOG00000016441	CPEB3	100	98.446	Gorilla_gorilla
ENSG00000107864	CPEB3	100	72.893	ENSHBUG00000004097	cpeb3	93	71.625	Haplochromis_burtoni
ENSG00000107864	CPEB3	100	96.848	ENSHGLG00000014022	CPEB3	100	96.848	Heterocephalus_glaber_female
ENSG00000107864	CPEB3	100	87.376	ENSHGLG00100005200	CPEB3	100	87.376	Heterocephalus_glaber_male
ENSG00000107864	CPEB3	100	69.774	ENSHCOG00000005747	cpeb3	100	69.522	Hippocampus_comes
ENSG00000107864	CPEB3	100	72.663	ENSIPUG00000018571	cpeb3	100	71.369	Ictalurus_punctatus
ENSG00000107864	CPEB3	100	95.994	ENSSTOG00000028061	CPEB3	100	95.994	Ictidomys_tridecemlineatus
ENSG00000107864	CPEB3	58	97.590	ENSJJAG00000009135	Cpeb3	100	97.590	Jaculus_jaculus
ENSG00000107864	CPEB3	100	73.034	ENSLBEG00000025961	cpeb3	100	72.969	Labrus_bergylta
ENSG00000107864	CPEB3	100	79.913	ENSLACG00000011307	CPEB3	92	79.624	Latimeria_chalumnae
ENSG00000107864	CPEB3	100	77.233	ENSLOCG00000007131	cpeb3	100	73.464	Lepisosteus_oculatus
ENSG00000107864	CPEB3	100	95.391	ENSLAFG00000018716	CPEB3	100	95.391	Loxodonta_africana
ENSG00000107864	CPEB3	100	90.442	ENSMFAG00000025613	CPEB3	100	90.442	Macaca_fascicularis
ENSG00000107864	CPEB3	100	98.836	ENSMMUG00000015050	CPEB3	100	98.836	Macaca_mulatta
ENSG00000107864	CPEB3	100	98.551	ENSMNEG00000045465	CPEB3	100	98.551	Macaca_nemestrina
ENSG00000107864	CPEB3	83	100.000	ENSMLEG00000031794	CPEB3	100	95.787	Mandrillus_leucophaeus
ENSG00000107864	CPEB3	100	73.061	ENSMAMG00000012794	cpeb3	100	73.529	Mastacembelus_armatus
ENSG00000107864	CPEB3	100	73.034	ENSMZEG00005012068	cpeb3	100	71.212	Maylandia_zebra
ENSG00000107864	CPEB3	100	85.159	ENSMGAG00000009148	CPEB3	99	84.006	Meleagris_gallopavo
ENSG00000107864	CPEB3	100	96.532	ENSMAUG00000002789	Cpeb3	100	96.532	Mesocricetus_auratus
ENSG00000107864	CPEB3	100	96.067	ENSMICG00000026866	CPEB3	100	96.067	Microcebus_murinus
ENSG00000107864	CPEB3	100	96.875	ENSMOCG00000016486	Cpeb3	100	96.875	Microtus_ochrogaster
ENSG00000107864	CPEB3	97	74.433	ENSMMOG00000008209	cpeb3	88	74.286	Mola_mola
ENSG00000107864	CPEB3	72	92.445	ENSMODG00000006673	CPEB3	100	81.855	Monodelphis_domestica
ENSG00000107864	CPEB3	100	74.857	ENSMALG00000009305	cpeb3	98	87.811	Monopterus_albus
ENSG00000107864	CPEB3	100	96.742	MGP_CAROLIEiJ_G0022910	Cpeb3	100	97.590	Mus_caroli
ENSG00000107864	CPEB3	100	97.151	ENSMUSG00000039652	Cpeb3	100	97.590	Mus_musculus
ENSG00000107864	CPEB3	100	96.738	MGP_PahariEiJ_G0014405	Cpeb3	100	97.590	Mus_pahari
ENSG00000107864	CPEB3	100	96.738	MGP_SPRETEiJ_G0023829	Cpeb3	100	97.590	Mus_spretus
ENSG00000107864	CPEB3	100	96.542	ENSMPUG00000017227	CPEB3	100	96.542	Mustela_putorius_furo
ENSG00000107864	CPEB3	100	95.621	ENSNGAG00000015621	Cpeb3	100	95.621	Nannospalax_galili
ENSG00000107864	CPEB3	100	73.199	ENSNBRG00000018343	cpeb3	91	72.896	Neolamprologus_brichardi
ENSG00000107864	CPEB3	100	99.417	ENSNLEG00000012600	CPEB3	100	99.417	Nomascus_leucogenys
ENSG00000107864	CPEB3	75	92.837	ENSMEUG00000009948	-	75	92.837	Notamacropus_eugenii
ENSG00000107864	CPEB3	100	94.965	ENSODEG00000004591	CPEB3	100	94.965	Octodon_degus
ENSG00000107864	CPEB3	100	95.251	ENSOCUG00000010454	CPEB3	100	95.251	Oryctolagus_cuniculus
ENSG00000107864	CPEB3	100	71.574	ENSORLG00000000726	cpeb3	100	70.742	Oryzias_latipes
ENSG00000107864	CPEB3	100	71.784	ENSORLG00020004475	cpeb3	100	71.387	Oryzias_latipes_hni
ENSG00000107864	CPEB3	100	71.930	ENSORLG00015011683	cpeb3	100	71.533	Oryzias_latipes_hsok
ENSG00000107864	CPEB3	100	71.533	ENSOMEG00000018265	cpeb3	93	70.158	Oryzias_melastigma
ENSG00000107864	CPEB3	100	96.512	ENSOGAG00000002002	CPEB3	100	96.512	Otolemur_garnettii
ENSG00000107864	CPEB3	100	97.664	ENSOARG00000016671	CPEB3	100	97.664	Ovis_aries
ENSG00000107864	CPEB3	90	99.099	ENSPPAG00000031528	CPEB3	100	99.099	Pan_paniscus
ENSG00000107864	CPEB3	100	97.956	ENSPPRG00000015654	CPEB3	100	97.956	Panthera_pardus
ENSG00000107864	CPEB3	62	99.770	ENSPTIG00000012018	CPEB3	97	99.655	Panthera_tigris_altaica
ENSG00000107864	CPEB3	100	99.857	ENSPTRG00000002753	CPEB3	100	99.857	Pan_troglodytes
ENSG00000107864	CPEB3	100	98.997	ENSPANG00000021561	CPEB3	100	98.997	Papio_anubis
ENSG00000107864	CPEB3	100	76.657	ENSPKIG00000015878	cpeb3	100	75.683	Paramormyrops_kingsleyae
ENSG00000107864	CPEB3	100	64.451	ENSPMGG00000022722	cpeb3	100	64.553	Periophthalmus_magnuspinnatus
ENSG00000107864	CPEB3	100	96.812	ENSPEMG00000008448	Cpeb3	100	96.812	Peromyscus_maniculatus_bairdii
ENSG00000107864	CPEB3	73	92.471	ENSPCIG00000017302	CPEB3	100	83.514	Phascolarctos_cinereus
ENSG00000107864	CPEB3	100	70.851	ENSPFOG00000011231	cpeb3	100	70.274	Poecilia_formosa
ENSG00000107864	CPEB3	100	71.328	ENSPLAG00000002852	cpeb3	100	71.408	Poecilia_latipinna
ENSG00000107864	CPEB3	100	71.469	ENSPMEG00000021572	cpeb3	100	71.045	Poecilia_mexicana
ENSG00000107864	CPEB3	100	71.328	ENSPREG00000003085	cpeb3	100	71.045	Poecilia_reticulata
ENSG00000107864	CPEB3	100	95.328	ENSPPYG00000002481	CPEB3	100	95.328	Pongo_abelii
ENSG00000107864	CPEB3	100	91.218	ENSPCAG00000012417	CPEB3	100	91.360	Procavia_capensis
ENSG00000107864	CPEB3	100	97.674	ENSPCOG00000023690	CPEB3	100	97.674	Propithecus_coquereli
ENSG00000107864	CPEB3	81	99.174	ENSPVAG00000007664	CPEB3	75	99.174	Pteropus_vampyrus
ENSG00000107864	CPEB3	100	72.893	ENSPNYG00000005300	cpeb3	100	71.625	Pundamilia_nyererei
ENSG00000107864	CPEB3	100	74.930	ENSPNAG00000012111	cpeb3	100	73.259	Pygocentrus_nattereri
ENSG00000107864	CPEB3	100	93.408	ENSRNOG00000020689	Cpeb3	94	93.408	Rattus_norvegicus
ENSG00000107864	CPEB3	100	96.788	ENSRBIG00000041079	CPEB3	100	96.788	Rhinopithecus_bieti
ENSG00000107864	CPEB3	100	99.270	ENSRROG00000031558	CPEB3	100	99.270	Rhinopithecus_roxellana
ENSG00000107864	CPEB3	62	97.872	ENSSBOG00000035843	CPEB3	100	97.872	Saimiri_boliviensis_boliviensis
ENSG00000107864	CPEB3	100	74.855	ENSSFOG00015004974	cpeb3	100	74.245	Scleropages_formosus
ENSG00000107864	CPEB3	59	80.535	ENSSFOG00015018275	-	99	80.637	Scleropages_formosus
ENSG00000107864	CPEB3	100	75.036	ENSSMAG00000013924	cpeb3	100	74.203	Scophthalmus_maximus
ENSG00000107864	CPEB3	100	74.711	ENSSDUG00000019766	cpeb3	100	74.928	Seriola_dumerili
ENSG00000107864	CPEB3	100	74.746	ENSSLDG00000021438	cpeb3	100	73.988	Seriola_lalandi_dorsalis
ENSG00000107864	CPEB3	52	99.725	ENSSARG00000001994	CPEB3	100	99.725	Sorex_araneus
ENSG00000107864	CPEB3	50	89.181	ENSSPUG00000003601	CPEB3	94	99.087	Sphenodon_punctatus
ENSG00000107864	CPEB3	100	73.596	ENSSPAG00000004725	cpeb3	100	73.743	Stegastes_partitus
ENSG00000107864	CPEB3	100	96.970	ENSSSCG00000010468	CPEB3	100	96.970	Sus_scrofa
ENSG00000107864	CPEB3	100	84.240	ENSTGUG00000008988	CPEB3	100	83.264	Taeniopygia_guttata
ENSG00000107864	CPEB3	60	92.548	ENSTBEG00000013125	-	60	92.548	Tupaia_belangeri
ENSG00000107864	CPEB3	100	92.561	ENSTTRG00000012334	CPEB3	100	92.418	Tursiops_truncatus
ENSG00000107864	CPEB3	100	93.978	ENSUAMG00000010827	CPEB3	100	93.978	Ursus_americanus
ENSG00000107864	CPEB3	100	97.668	ENSVVUG00000021375	CPEB3	100	97.668	Vulpes_vulpes
ENSG00000107864	CPEB3	100	75.215	ENSXETG00000012190	cpeb3	98	75.788	Xenopus_tropicalis
ENSG00000107864	CPEB3	100	71.825	ENSXCOG00000006122	cpeb3	100	71.470	Xiphophorus_couchianus
ENSG00000107864	CPEB3	100	71.674	ENSXMAG00000007652	cpeb3	94	93.836	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	20639532.	IDA	Process
GO:0000900	translation repressor activity, mRNA regulatory element binding	21873635.	IBA	Function
GO:0000900	translation repressor activity, mRNA regulatory element binding	-	ISS	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	22730302.	IDA	Function
GO:0003730	mRNA 3'-UTR binding	21873635.	IBA	Function
GO:0003730	mRNA 3'-UTR binding	22711986.	IDA	Function
GO:0003730	mRNA 3'-UTR binding	-	ISS	Function
GO:0005515	protein binding	20639532.21336257.22711986.22730302.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	20639532.22730302.	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	20639532.22730302.	IDA	Component
GO:0005737	cytoplasm	-	ISS	Component
GO:0006412	translation	-	IEA	Process
GO:0007616	long-term memory	-	ISS	Process
GO:0008135	translation factor activity, RNA binding	21873635.	IBA	Function
GO:0008135	translation factor activity, RNA binding	22711986.	IDA	Function
GO:0008135	translation factor activity, RNA binding	-	ISS	Function
GO:0014069	postsynaptic density	-	IEA	Component
GO:0017148	negative regulation of translation	21336257.22711986.	IDA	Process
GO:0030014	CCR4-NOT complex	21336257.	IDA	Component
GO:0030054	cell junction	-	IEA	Component
GO:0030425	dendrite	-	ISS	Component
GO:0035613	RNA stem-loop binding	-	ISS	Function
GO:0035925	mRNA 3'-UTR AU-rich region binding	-	ISS	Function
GO:0043005	neuron projection	21873635.	IBA	Component
GO:0043005	neuron projection	22730302.	IDA	Component
GO:0043005	neuron projection	-	ISS	Component
GO:0043022	ribosome binding	21873635.	IBA	Function
GO:0045202	synapse	21873635.	IBA	Component
GO:0045202	synapse	-	ISS	Component
GO:0045211	postsynaptic membrane	-	IEA	Component
GO:0045727	positive regulation of translation	-	ISS	Process
GO:0048167	regulation of synaptic plasticity	-	ISS	Process
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	21336257.	IDA	Process
GO:0060998	regulation of dendritic spine development	-	ISS	Process
GO:0060999	positive regulation of dendritic spine development	-	ISS	Process
GO:0061158	3'-UTR-mediated mRNA destabilization	21336257.	IDA	Process
GO:0071230	cellular response to amino acid stimulus	20639532.22730302.	IDA	Process
GO:0071230	cellular response to amino acid stimulus	-	ISS	Process
GO:0097440	apical dendrite	-	ISS	Component
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	21336257.	IDA	Process
GO:1900248	negative regulation of cytoplasmic translational elongation	-	ISS	Process
GO:1900365	positive regulation of mRNA polyadenylation	-	ISS	Process
GO:1990124	messenger ribonucleoprotein complex	21873635.	IBA	Component
GO:2000766	negative regulation of cytoplasmic translation	21873635.	IBA	Process

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.