EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
20884074	Minichromosome maintenance (MCM) protein 4 as a marker for proliferation and its clinical and clinicopathological significance in non-small cell lung cancer.	Lung Cancer	2011 May	Kikuchi J	doi: 10.1016/j.lungcan.2010.08.020
17222376	[Expression and significance of MCM4 in esophageal cancer].	Ai Zheng	2007 Jan	Huang XP	-

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr8	47970637	Missense_Mutation	novel	Q521E	0.31
BLCA	chr8	47962092	Missense_Mutation	novel	Y92C	0.27
BLCA	chr8	47961540	Missense_Mutation	NA	S32C	0.33
BLCA	chr8	47974804	Nonsense_Mutation	novel	S736*	0.34
BLCA	chr8	47970003	Missense_Mutation	novel	E460D	0.74
BLCA	chr8	47962949	Missense_Mutation	rs562067900	N201S	0.49
BLCA	chr8	47962834	Missense_Mutation	novel	P191H	0.15
BLCA	chr8	47962159	Silent	novel	Q114Q	0.11
BLCA	chr8	47975764	Missense_Mutation	NA	L805F	0.18
BLCA	chr8	47974893	Missense_Mutation	rs149597772	R766W	0.27
BLCA	chr8	47961518	Missense_Mutation	NA	R25W	0.2
BLCA	chr8	47970799	Missense_Mutation	novel	E575K	0.32
BLCA	chr8	47973038	Missense_Mutation	novel	E704Q	0.8
BRCA	chr8	47970732	Silent	NA	E552E	0.49
BRCA	chr8	47975822	Nonsense_Mutation	NA	E825*	0.38
BRCA	chr8	47974904	Silent	NA	L769L	0.17
BRCA	chr8	47970655	Missense_Mutation	rs751154452	V527I	0.08
BRCA	chr8	47974748	Missense_Mutation	NA	M717I	0.19
BRCA	chr8	47969847	Silent	NA	V408V	0.15
BRCA	chr8	47963002	Missense_Mutation	NA	D219H	0.21
BRCA	chr8	47966325	Missense_Mutation	NA	E324V	0.25
BRCA	chr8	47962992	Silent	NA	I215I	0.12
BRCA	chr8	47974912	Missense_Mutation	NA	S772C	0.25
BRCA	chr8	47970032	Missense_Mutation	novel	I470T	0.06
BRCA	chr8	47971419	Nonsense_Mutation	novel	K627*	0.07
CESC	chr8	47962992	Missense_Mutation	novel	I215M	0.1
CESC	chr8	47975722	Silent	novel	S791S	0.31
CESC	chr8	47961561	Missense_Mutation	novel	G39D	0.38
CESC	chr8	47962777	Missense_Mutation	rs369755637	R172H	0.36
CESC	chr8	47966366	Missense_Mutation	rs760155775	A338T	0.37
CESC	chr8	47967445	Silent	novel	L378L	0.37
COAD	chr8	47962944	Splice_Site	novel	X200_splice	0.27
COAD	chr8	47969821	Nonsense_Mutation	NA	R400*	0.34
COAD	chr8	47976768	Missense_Mutation	NA	R861H	0.24
COAD	chr8	47973008	Missense_Mutation	rs777231755	A694T	0.19
COAD	chr8	47962188	Missense_Mutation	NA	G124V	0.32
COAD	chr8	47966381	Missense_Mutation	rs768182076	R343C	0.19
COAD	chr8	47972915	Missense_Mutation	novel	A663S	0.1
COAD	chr8	47971419	Frame_Shift_Del	NA	*T629Qfs18**	0.36
COAD	chr8	47969806	Nonsense_Mutation	NA	R395*	0.23
COAD	chr8	47971366	Missense_Mutation	NA	A609V	0.39
COAD	chr8	47961200	Frame_Shift_Del	novel	*A21Pfs70**	0.14
COAD	chr8	47961640	Frame_Shift_Del	novel	*D66Tfs25**	0.45
COAD	chr8	47961641	Missense_Mutation	novel	D66H	0.45
COAD	chr8	47962763	Splice_Site	NA	X168_splice	0.1
COAD	chr8	47971419	Frame_Shift_Del	NA	*T629Qfs18**	0.25
COAD	chr8	47969976	Missense_Mutation	novel	E451D	0.26
COAD	chr8	47974804	Nonsense_Mutation	novel	S736*	0.41
COAD	chr8	47966338	Silent	rs200670710	C328C	0.17
DLBC	chr8	47976772	Silent	novel	L862L	0.18
ESCA	chr8	47969781	Splice_Site	novel	X392_splice	0.08
ESCA	chr8	47969918	Missense_Mutation	novel	L432R	0.12
GBM	chr8	47976689	Missense_Mutation	rs747765310	I835V	0.46
GBM	chr8	47967377	Nonsense_Mutation	novel	E356*	0.09
GBM	chr8	47967380	Missense_Mutation	novel	S357P	0.22
GBM	chr8	47961615	Missense_Mutation	novel	V57G	0.2
GBM	chr8	47962174	Silent	novel	G119G	0.41
GBM	chr8	47962175	Missense_Mutation	novel	S120P	0.39
GBM	chr8	47971446	Missense_Mutation	novel	L636V	0.09
GBM	chr8	47967443	Missense_Mutation	novel	L378F	0.04
GBM	chr8	47970015	Silent	novel	S464S	0.09
GBM	chr8	47974893	Missense_Mutation	rs149597772	R766W	0.42
GBM	chr8	47967425	Missense_Mutation	novel	L372M	0.05
GBM	chr8	47974932	Missense_Mutation	novel	G779S	0.37
HNSC	chr8	47971369	Missense_Mutation	NA	R610L	0.22
HNSC	chr8	47962189	Silent	novel	G124G	0.26
HNSC	chr8	47969931	Silent	novel	A436A	0.19
HNSC	chr8	47972944	Missense_Mutation	NA	Q672H	0.31
HNSC	chr8	47962064	Missense_Mutation	novel	D83Y	0.07
HNSC	chr8	47974847	Silent	novel	S750S	0.08
HNSC	chr8	47975799	Missense_Mutation	novel	A817V	0.3
HNSC	chr8	47961651	Missense_Mutation	novel	F69S	0.09
HNSC	chr8	47970720	Missense_Mutation	novel	M548I	0.23
KIRC	chr8	47961547	Silent	NA	S34S	0.39
LGG	chr8	47970789	Nonsense_Mutation	novel	C571*	0.41
LGG	chr8	47973029	Missense_Mutation	rs767399226	R701W	0.45
LGG	chr8	47974759	Missense_Mutation	novel	G721D	0.41
LIHC	chr8	47970510	Splice_Site	novel	X479_splice	0.05
LIHC	chr8	47961644	Missense_Mutation	rs755044869	V67M	0.45
LIHC	chr8	47971363	Missense_Mutation	NA	N608I	0.2
LUAD	chr8	47969965	Missense_Mutation	NA	L448V	0.24
LUAD	chr8	47976728	Missense_Mutation	NA	A848S	0.15
LUAD	chr8	47970788	Missense_Mutation	NA	C571F	0.34
LUAD	chr8	47961101	5'UTR	novel		0.55
LUAD	chr8	47967471	Missense_Mutation	NA	R387K	0.24
LUAD	chr8	47970830	Nonsense_Mutation	novel	S585*	0.4
LUAD	chr8	47970831	Silent	rs767159783	S585S	0.4
LUAD	chr8	47962077	Missense_Mutation	NA	S87I	0.13
LUAD	chr8	47961563	Missense_Mutation	rs755169604	E40K	0.37
LUAD	chr8	47970817	Missense_Mutation	NA	E581K	0.12
LUAD	chr8	47970574	Missense_Mutation	novel	F500I	0.06
LUAD	chr8	47970796	Missense_Mutation	NA	D574Y	0.16
LUAD	chr8	47970805	Missense_Mutation	NA	D577Y	0.29
LUAD	chr8	47966310	Missense_Mutation	NA	R319L	0.19
LUAD	chr8	47970849	Frame_Shift_Del	novel	*E592Nfs55**	0.1
LUSC	chr8	47966214	Missense_Mutation	novel	G287D	0.26
LUSC	chr8	47974903	Missense_Mutation	novel	L769Q	0.06
LUSC	chr8	47975762	Missense_Mutation	novel	L805M	0.12
LUSC	chr8	47964693	Missense_Mutation	NA	M271I	0.22
LUSC	chr8	47966327	Missense_Mutation	NA	P325A	0.23
LUSC	chr8	47970868	Missense_Mutation	NA	I598F	0.3
LUSC	chr8	47961672	Missense_Mutation	rs752922408	H76R	0.23
LUSC	chr8	47970711	Silent	rs374108311	A545A	0.1
LUSC	chr8	47970877	Splice_Site	novel	X600_splice	0.26
LUSC	chr8	47972944	Missense_Mutation	NA	Q672H	0.16
LUSC	chr8	47961531	Missense_Mutation	novel	A29D	0.2
LUSC	chr8	47961530	Missense_Mutation	novel	A29S	0.15
LUSC	chr8	47976825	3'UTR	rs377300189		0.18
LUSC	chr8	47967402	Missense_Mutation	novel	G364E	0.35
LUSC	chr8	47962058	Missense_Mutation	NA	P81T	0.39
OV	chr8	47970054	Missense_Mutation	novel	K477N	0.26
OV	chr8	47970607	Missense_Mutation	NA	D511N	0.29
OV	chr8	47974817	Frame_Shift_Ins	novel	*A741Lfs8**	0.32
OV	chr8	47974818	In_Frame_Ins	novel	A741delinsVLGFFVCFFET	0.3
OV	chr8	47970606	Silent	rs774640100	G510G	0.46
PRAD	chr8	47966255	Missense_Mutation	NA	E301K	0.55
READ	chr8	47970804	Silent	rs148525401	F576F	0.56
READ	chr8	47969954	Missense_Mutation	NA	K444T	0.15
READ	chr8	47974850	Silent	rs780201599	N751N	0.48
READ	chr8	47962065	Missense_Mutation	novel	D83A	0.09
READ	chr8	47975777	Missense_Mutation	NA	L810V	0.09
SARC	chr8	47966316	Missense_Mutation	novel	R321H	0.48
SKCM	chr8	47971375	Missense_Mutation	novel	S612F	0.45
SKCM	chr8	47970626	Missense_Mutation	NA	S517F	0.17
SKCM	chr8	47970627	Silent	NA	S517S	0.18
SKCM	chr8	47974767	Missense_Mutation	rs201708189	R724W	0.4
SKCM	chr8	47962976	Missense_Mutation	novel	V210A	0.33
SKCM	chr8	47971366	Missense_Mutation	NA	A609V	0.16
SKCM	chr8	47961543	Missense_Mutation	rs755898364	P33L	0.45
SKCM	chr8	47961544	Silent	rs199890906	P33P	0.45
SKCM	chr8	47970703	Missense_Mutation	NA	L543F	0.46
SKCM	chr8	47970626	Missense_Mutation	NA	S517F	0.48
SKCM	chr8	47966267	Nonsense_Mutation	NA	Q305*	0.22
SKCM	chr8	47961606	Missense_Mutation	NA	S54L	0.16
SKCM	chr8	47974826	Silent	novel	A743A	0.12
SKCM	chr8	47974827	Missense_Mutation	novel	H744Y	0.12
SKCM	chr8	47970689	Missense_Mutation	NA	S538F	0.11
SKCM	chr8	47970660	Silent	NA	P528P	0.44
SKCM	chr8	47973027	Missense_Mutation	NA	P700L	0.17
SKCM	chr8	47966357	Missense_Mutation	novel	H335Y	0.29
STAD	chr8	47969895	Silent	rs376248536	T424T	0.16
STAD	chr8	47966338	Silent	rs200670710	C328C	0.29
STAD	chr8	47971419	Frame_Shift_Del	NA	*T629Qfs18**	0.25
STAD	chr8	47974893	Missense_Mutation	rs149597772	R766W	0.09
STAD	chr8	47966283	Missense_Mutation	NA	A310V	0.18
STAD	chr8	47966338	Silent	rs200670710	C328C	0.16
STAD	chr8	47975831	Missense_Mutation	rs757711165	R828W	0.17
STAD	chr8	47974938	Missense_Mutation	rs765226208	V781M	0.16
STAD	chr8	47973027	Missense_Mutation	NA	P700L	0.33
STAD	chr8	47970594	Silent	novel	I506I	0.24
STAD	chr8	47976767	Missense_Mutation	rs375720200	R861C	0.34
STAD	chr8	47971419	Frame_Shift_Del	NA	*T629Qfs18**	0.26
STAD	chr8	47962304	Splice_Site	NA	X134_splice	0.09
STAD	chr8	47975738	Missense_Mutation	rs749728850	R797W	0.26
STAD	chr8	47976754	Silent	NA	T856T	0.17
STAD	chr8	47974960	Missense_Mutation	rs781271560	T788M	0.44
STAD	chr8	47971418	Frame_Shift_Ins	novel	*T629Nfs4**	0.21
STAD	chr8	47970876	Splice_Region	NA	K600K	0.13
STAD	chr8	47976764	Missense_Mutation	rs142208176	V860M	0.22
THCA	chr8	47971363	Missense_Mutation	NA	N608I	0.23
THCA	chr8	47962852	Frame_Shift_Ins	novel	*G198Kfs19**	0.04
UCEC	chr8	47966246	Missense_Mutation	NA	E298K	0.37
UCEC	chr8	47970804	Silent	rs148525401	F576F	0.35
UCEC	chr8	47970533	Missense_Mutation	NA	G486D	0.28
UCEC	chr8	47975765	Missense_Mutation	rs775169389	K806E	0.36
UCEC	chr8	47976928	3'UTR	novel		0.31
UCEC	chr8	47970654	Silent	rs34157149	L526L	0.16
UCEC	chr8	47969880	Silent	novel	I419I	0.53
UCEC	chr8	47970023	Missense_Mutation	novel	A467D	0.15
UCEC	chr8	47970577	Missense_Mutation	rs773264700	R501W	0.42
UCEC	chr8	47972982	Missense_Mutation	rs763060839	A685V	0.4
UCEC	chr8	47976859	3'UTR	novel		0.71
UCEC	chr8	47962763	Splice_Site	NA	X168_splice	0.39
UCEC	chr8	47975816	Missense_Mutation	novel	L823F	0.3
UCEC	chr8	47972931	Missense_Mutation	NA	A668V	0.18
UCEC	chr8	47976790	3'UTR	novel		0.29
UCEC	chr8	47969919	Silent	NA	L432L	0.43
UCEC	chr8	47969806	Nonsense_Mutation	NA	R395*	0.25
UCEC	chr8	47974845	Missense_Mutation	rs745883715	S750A	0.17
UCEC	chr8	47962802	Missense_Mutation	novel	E180D	0.27
UCEC	chr8	47964695	Missense_Mutation	NA	R272K	0.67
UCEC	chr8	47976851	3'UTR	novel		0.06
UCEC	chr8	47976716	Silent	NA	L844L	0.05
UCEC	chr8	47962776	Missense_Mutation	rs771112920	R172C	0.37
UCEC	chr8	47975831	Missense_Mutation	rs757711165	R828W	0.25
UCEC	chr8	47976723	Missense_Mutation	rs566436447	A846V	0.71
UCEC	chr8	47961675	Missense_Mutation	novel	S77Y	0.4
UCEC	chr8	47971419	Frame_Shift_Del	NA	*T629Qfs18**	0.32
UCEC	chr8	47961573	Missense_Mutation	NA	T43N	0.38
UCEC	chr8	47976859	3'UTR	novel		0.09
UCEC	chr8	47962213	Silent	novel	D132D	0.25
UCEC	chr8	47966246	Missense_Mutation	NA	E298K	0.44
UCEC	chr8	47971419	Frame_Shift_Del	NA	*T629Qfs18**	0.28
UCEC	chr8	47962052	Splice_Site	novel	X79_splice	0.27
UCEC	chr8	47964612	Silent	novel	I244I	0.36
UCEC	chr8	47966339	Missense_Mutation	rs768674866	G329R	0.32
UCEC	chr8	47976825	3'UTR	rs377300189		0.11
UCEC	chr8	47970577	Missense_Mutation	rs773264700	R501W	0.46
UCEC	chr8	47970804	Silent	rs148525401	F576F	0.27
UCEC	chr8	47961560	Missense_Mutation	novel	G39C	0.11
UCEC	chr8	47962110	Missense_Mutation	NA	R98Q	0.43
UCEC	chr8	47966328	Missense_Mutation	NA	P325R	0.36
UCEC	chr8	47971366	Missense_Mutation	NA	A609V	0.23
UCEC	chr8	47972893	Silent	rs758743457	D655D	0.13
UCEC	chr8	47964597	Missense_Mutation	novel	M239I	0.38
UCEC	chr8	47969865	Silent	NA	T414T	0.17
UCEC	chr8	47974917	Missense_Mutation	novel	T774A	0.43
UCEC	chr8	47966342	Missense_Mutation	rs144766420	R330C	0.36
UCS	chr8	47961204	Silent	novel	P20P	1

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
READ	DEL	0.0727	0.20625
UCS	AMP	0.6071	4.2724e-06

Survival Analysis

Cancer	P-value	Q-value
THYM	0.006	Kaplan-Meier Survival Analysis
KIRC	0.026	Kaplan-Meier Survival Analysis
SARC	0.00051	Kaplan-Meier Survival Analysis
MESO	0.00012	Kaplan-Meier Survival Analysis
ACC	0.00011	Kaplan-Meier Survival Analysis
SKCM	0.012	Kaplan-Meier Survival Analysis
LUSC	0.011	Kaplan-Meier Survival Analysis
KIRP	0.0001	Kaplan-Meier Survival Analysis
COAD	0.009	Kaplan-Meier Survival Analysis
PAAD	0.00033	Kaplan-Meier Survival Analysis
CESC	0.0031	Kaplan-Meier Survival Analysis
READ	0.029	Kaplan-Meier Survival Analysis
KICH	0.0011	Kaplan-Meier Survival Analysis
UCEC	0.00018	Kaplan-Meier Survival Analysis
LIHC	0.00015	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
THCA	0.01	Kaplan-Meier Survival Analysis
LUAD	0.00011	Kaplan-Meier Survival Analysis
UVM	0.00026	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000104738 (Gene tree)
Gene ID: 4173
Gene Symbol: MCM4
Alias: CDC54|hCdc21|P1-Cdc21|MGC33310|CDC21
Full Name: minichromosome maintenance complex component 4
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 17,976 bases
Position: chr8:47,960,185-47,978,160
Accession: 6947
RBP type: non-canonical RBP
Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000520994	MCM4-210	522	-	-	- (aa)	-	-
ENST00000521261	MCM4-212	1342	-	-	- (aa)	-	-
ENST00000519138	MCM4-206	927	-	-	- (aa)	-	-
ENST00000648554	MCM4-220	755	-	ENSP00000496985	191 (aa)	-	-
ENST00000521151	MCM4-211	1125	-	-	- (aa)	-	-
ENST00000519170	MCM4-207	734	-	-	- (aa)	-	-
ENST00000523944	MCM4-214	4105	-	ENSP00000430194	863 (aa)	-	P33991
ENST00000517709	MCM4-202	842	-	-	- (aa)	-	-
ENST00000524086	MCM4-215	547	-	ENSP00000427829	81 (aa)	-	E5RG53
ENST00000648407	MCM4-217	2598	-	ENSP00000497881	742 (aa)	-	-
ENST00000262105	MCM4-201	4183	-	ENSP00000262105	863 (aa)	-	P33991
ENST00000519470	MCM4-208	498	-	-	- (aa)	-	-
ENST00000518221	MCM4-203	572	-	ENSP00000430329	140 (aa)	-	E5RFR3
ENST00000649919	MCM4-222	2957	-	ENSP00000498202	813 (aa)	-	UPI000387DE53
ENST00000520637	MCM4-209	1981	-	ENSP00000427875	582 (aa)	-	E5RG31
ENST00000649838	MCM4-221	3157	-	ENSP00000497648	904 (aa)	-	-
ENST00000649973	MCM4-223	4062	-	ENSP00000496964	863 (aa)	-	UPI000013D25C
ENST00000518382	MCM4-204	366	-	ENSP00000430864	27 (aa)	-	E5RHP5
ENST00000650327	MCM4-225	235	-	-	- (aa)	-	-
ENST00000650216	MCM4-224	2399	-	ENSP00000497093	749 (aa)	-	-
ENST00000647877	MCM4-216	1256	-	ENSP00000497251	107 (aa)	-	-
ENST00000523853	MCM4-213	354	-	-	- (aa)	-	-
ENST00000648519	MCM4-218	3226	-	ENSP00000497176	160 (aa)	-	-
ENST00000648533	MCM4-219	733	-	-	- (aa)	-	-
ENST00000518680	MCM4-205	862	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000104738's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03030	DNA replication	KEGG
hsa04110	Cell cycle	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000104738	rs762679	8	47972876	A	Red blood cell count	27863252	[0.022-0.042] unit decrease	0.03194922	EFO_0004305
ENSG00000104738	rs762679	8	47972876	A	Mean corpuscular volume	27863252	[0.025-0.044] unit increase	0.03467907	EFO_0004526
ENSG00000104738	rs762679	8	47972876	?	Mean corpuscular hemoglobin	30595370			EFO_0004527
ENSG00000104738	rs762679	8	47972876	?	Eosinophil counts	30595370			EFO_0004842

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000104738's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000104738	MCM4	99	68.220	FBgn0015929	dpa	99	61.469	Drosophila_melanogaster
ENSG00000104738	MCM4	90	47.701	FBgn0014861	Mcm2	67	33.651	Drosophila_melanogaster
ENSG00000104738	MCM4	89	50.000	ENSG00000073111	MCM2	83	40.556	Homo_sapiens
ENSG00000104738	MCM4	86	66.667	YPR019W	MCM4	80	47.397	Saccharomyces_cerevisiae

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000082	G1/S transition of mitotic cell cycle	-	TAS	Process
GO:0000784	nuclear chromosome, telomeric region	19135898.	HDA	Component
GO:0003697	single-stranded DNA binding	-	IEA	Function
GO:0004003	ATP-dependent DNA helicase activity	9305914.	IDA	Function
GO:0005515	protein binding	12364596.15232106.16902406.17296731.22190034.22540012.23764002.24299456.24407287.25036637.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	8265339.	NAS	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0006260	DNA replication	9465298.	NAS	Process
GO:0006260	DNA replication	-	TAS	Process
GO:0006268	DNA unwinding involved in DNA replication	-	IEA	Process
GO:0006270	DNA replication initiation	-	IEA	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0042555	MCM complex	17296731.	IDA	Component

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.