EuRBPDB

  • Home
  • Cancer
  • Family
  • Species
  • RBPredictor
  • Search
  • Download
  • Submit
  • Help
  • Contact
TCGA tumor abbreviations
  • ACCAdrenocortical carcinoma
  • BLCABladder Urothelial Carcinoma
  • BRCABreast invasive carcinoma
  • CESCCervical squamous cell carcinoma and endocervical adenocarcinoma
  • CHOLCholangio carcinoma
  • COADColon adenocarcinoma
  • DLBCLymphoid Neoplasm Diffuse Large B-cell Lymphoma
  • ESCAEsophageal carcinoma
  • GBMGlioblastoma multiforme
  • HNSCHead and Neck squamous cell carcinoma
  • KICHKidney Chromophobe
  • KIRCKidney renal clear cell carcinoma
  • KIRPKidney renal papillary cell carcinoma
  • LAMLAcute Myeloid Leukemia
  • LGGBrain Lower Grade Glioma
  • LIHCLiver hepatocellular carcinoma
  • LUADLung adenocarcinoma
  • LUSCLung squamous cell carcinoma
  • MESOMesothelioma
  • OVOvarian serous cystadenocarcinoma
  • PAADPancreatic adenocarcinoma
  • PCPGPheochromocytoma and Paraganglioma
  • PRADProstate adenocarcinoma
  • READRectum adenocarcinoma
  • SARCSarcoma
  • SKCMSkin Cutaneous Melanoma
  • STADStomach adenocarcinoma
  • TGCTThyroid carcinoma
  • THCAThyroid carcinoma
  • THYMThymoma
  • UCECUterine Corpus Endometrial Carcinoma
  • UCSUterine Carcinosarcoma
  • UVMUveal Melanoma

Note: Click here to get the extension of tumor abbreviations.


  • Cancer Related Information
  • Basic Information

Cancer associated literatures
PIDTitleArticle TimeAuthorDoi
14503807CTCF gene mutations in invasive ductal breast cancer.Breast Cancer Res Treat2003 AugAulmann S-
23553099The cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells.Int J Cancer2013 Oct 1Tiffen JCdoi: 10.1002/ijc.28184
11782357Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter tts DNA-binding specificity.Cancer Res2002 Jan 1Filippova GN-
24130125High frequency strand slippage mutations in CTCF in MSI-positive endometrial cancers.Hum Mutat2014 JanZighelboim I-
26784546TGF-β/β2-spectrin/CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome.J Clin Invest2016 FebChen Jdoi: 10.1172/JCI80937
24794443CTCF haploinsufficiency destabilizes DNA methylation and predisposes to cancer.Cell Rep2014 May 22Kemp CJdoi: 10.1016/j.celrep.2014.04.004
19737964Decreased poly(ADP-ribosyl)ation of CTCF, a transcription factor, is associated with breast cancer phenotype and cell proliferation.Clin Cancer Res2009 Sep 15Docquier Fdoi: 10.1158/1078-0432.CCR-09-0329
19450526Epigenetic silencing of the p16(INK4a) tumor suppressor is associated with loss of CTCF binding and a chromatin boundary.Mol Cell2009 May 15Witcher Mdoi: 10.1016/j.molcel.2009.04.001.
27490693Mutational Biases Drive Elevated Rates of Substitution at Regulatory Sites across Cancer Types.PLoS Genet2016 Aug 4Kaiser VBdoi: 10.1371/journal.pgen.1006207
16140944Reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter coincides with derepression of this cancer-testis gene in lung cancer cells.Cancer Res2005 Sep 1Hong JA-
15958555Heightened expression of CTCF in breast cancer cells is associated with resistance to apoptosis.Cancer Res2005 Jun 15Docquier F-
19513555Aberrant epigenetic modifications in the CTCF binding domain of the IGF2/H19 gene in prostate cancer compared with benign prostate hyperplasia.Int J Oncol2009 JulParadowska A-
26478432CTCF negatively regulates HOXA10 expression in breast cancer cells.Biochem Biophys Res Commun2015 Nov 27Mustafa Mdoi: 10.1016/j.bbrc.2015.10.058
24174344CTCF mediates the TERT enhancer-promoter interactions in lung cancer cells: identification of a novel enhancer region involved in the regulation of TERT gene.Int J Cancer2014 May 15Eldholm Vdoi: 10.1002/ijc.28570
23908591A novel mechanism for CTCF in the epigenetic regulation of Bax in breast cancer cells.Neoplasia2013 AugM??ndez-Catal?? CF-
24842653The promoter methylation status and mRNA expression levels of CTCF and SIRT6 in sporadic breast cancer.DNA Cell Biol2014 SepWang Ddoi: 10.1089/dna.2013.2257
26330387Patterns of CTCF and ZFHX3 Mutation and Associated Outcomes in Endometrial Cancer.J Natl Cancer Inst2015 Sep 1Walker CJdoi: 10.1093/jnci/djv249
26747525IL-10 and integrin signaling pathways are associated with head and neck cancer progression.BMC Genomics2016 Jan 8Bornstein Sdoi: 10.1186/s12864-015-2359-6.
25592173Systematical analyses of variants in CTCF-binding sites identified a novel lung cancer susceptibility locus among Chinese population.Sci Rep2015 Jan 16Dai Jdoi: 10.1038/srep07833.
25499215Frequent disruption of chromodomain helicase DNA-binding protein 8 (CHD8) and functionally associated chromatin regulators in prostate cancer.Neoplasia2014 DecDamaschke NAdoi: 10.1016/j.neo.2014.10.003.
26549033DNA methylation reactivates GAD1 expression in cancer by preventing CTCF-mediated polycomb repressive complex 2 recruitment.Oncogene2016 Jul 28Yan Hdoi: 10.1038/onc.2015.423
28319062CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic.Oncogene2017 Jul 20Marshall ADdoi: 10.1038/onc.2017.25
27974201Functional Mutations Form at CTCF-Cohesin Binding Sites in Melanoma Due to Uneven Nucleotide Excision Repair across the Motif.Cell Rep2016 Dec 13Poulos RCdoi: 10.1016/j.celrep.2016.11.055.
27762310Chromatin accessibility contributes to simultaneous mutations of cancer genes.Sci Rep2016 Oct 20Shi Ydoi: 10.1038/srep35270.
29956775Identification of open chromosomal regions and key genes in prostate cancer via integrated analysis of DNaseseq and RNAseq data.Mol Med Rep2018 AugWei Xdoi: 10.3892/mmr.2018.9193
30086769CTCF maintains regulatory homeostasis of cancer pathways.Genome Biol2018 Aug 7Aitken SJdoi: 10.1186/s13059-018-1484-3.
30296942CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops.Genome Biol2018 Oct 8Guo Ydoi: 10.1186/s13059-018-1531-0.

Expression in 33 cancers

Mutations
CancerChrPosition Mutation TypedbSNPProtein-change Allele FreqRBD
BLCAchr1667620736Nonsense_MutationnovelE376*0.48
BLCAchr1667620678Splice_SitenovelX363_splice0.06
BLCAchr1667616843Missense_MutationNAF351L0.18
BLCAchr1667620734Missense_MutationnovelG375A0.36
BLCAchr1667611309SilentnovelP159P0.16
BLCAchr1667636743Nonsense_MutationNAE631*0.4
BLCAchr1667628453SilentNAQ534Q0.25
BLCAchr1667611181Nonsense_MutationNAQ117*0.34
BLCAchr1667637747Nonsense_MutationNAE687*0.1
BLCAchr1667616853Missense_MutationNAS354F0.46
BLCAchr1667616829Missense_MutationnovelT346N0.22
BLCAchr1667611142Nonsense_MutationnovelE104*0.45
BLCAchr1667611265Missense_MutationnovelE145Q0.5
BLCAchr1667611961Missense_MutationnovelK264N0.53
BLCAchr1667620773Missense_MutationNAS388N0.29
BLCAchr1667616756Missense_MutationnovelH322Y0.36
BLCAchr1667636805SilentnovelR651R0.08
BLCAchr1667616853Missense_MutationnovelS354Y0.15
BLCAchr1667628444SilentNAT531T0.23
BLCAchr1667612037Missense_MutationnovelD290N0.21
BRCAchr1667612020Missense_MutationNAH284P0.24
BRCAchr1667611604Missense_MutationNAK258E0.42
BRCAchr1667611515Missense_MutationNAF228S0.4
BRCAchr1667611195SilentNAP121P0.1
BRCAchr1667611405Nonsense_MutationNAW191*0.36
BRCAchr1667628540SilentNAT563T0.49
BRCAchr1667612016Missense_MutationNAR283C0.38
BRCAchr1667611615Splice_SiteNAX261_splice0.7
BRCAchr1667612019Missense_MutationNAH284Y0.68
BRCAchr1667620742Missense_MutationNAP378A0.73
BRCAchr1667637747Missense_MutationnovelE687K0.13
BRCAchr1667610934SilentNAE34E0.2
BRCAchr1667612019Missense_MutationNAH284N0.57
BRCAchr1667611509Missense_MutationNAY226C0.26
BRCAchr1667610995Frame_Shift_DelnovelN55Tfs*70.59
BRCAchr1667621528Nonsense_MutationNAE432*0.31
BRCAchr1667610893Nonsense_MutationNAE21*0.86
BRCAchr1667611950Splice_RegionnovelG261delinsVR0.71
BRCAchr16676379593'UTRnovel0.32
BRCAchr1667612031Missense_MutationNAH288D0.43
BRCAchr1667611610Splice_SitenovelX260_splice0.73
BRCAchr1667610914Frame_Shift_DelnovelR28Pfs*170.7
CESCchr16676379943'UTRnovel0.28
CESCchr1667626711Missense_MutationNAR505T0.2
CESCchr1667612059Missense_MutationnovelH297L0.54
CESCchr1667636743Nonsense_MutationNAE631*0.3
CESCchr1667611435Frame_Shift_InsNAT204Nfs*260.3
CESCchr1667637838Missense_MutationnovelT717M0.57
CESCchr16676389303'UTRnovel0.53
CESCchr16676382393'UTRnovel0.29
CESCchr1667628510Silentrs749116676A553A0.5
CESCchr1667621576Nonsense_Mutationrs769948988R448*0.28
CESCchr1667612005Missense_MutationNAS279L0.42
CESCchr16676386873'UTRnovel0.55
CESCchr1667629525Missense_MutationNAS610F0.48
CHOLchr1667616753Frame_Shift_InsnovelH322Lfs*120.31
CHOLchr1667610974Missense_MutationnovelG48C0.05
COADchr1667616826Missense_MutationNAH345R0.39
COADchr1667611435Frame_Shift_InsNAT204Nfs*260.1
COADchr1667611184In_Frame_DelnovelP121_V126del0.04
COADchr1667628421Missense_Mutationrs767996920A524T0.3
COADchr1667610917Missense_Mutationrs771567232R29W0.43
COADchr1667620739Missense_MutationNAR377C0.43
COADchr1667611436Frame_Shift_DelNAT204Qfs*180.12
COADchr1667611372Frame_Shift_InsNAE182Gfs*90.36
COADchr1667626677Missense_MutationNAR494C0.25
COADchr1667612001Missense_MutationnovelR278C0.24
COADchr1667637752Frame_Shift_DelNAE691Sfs*300.45
COADchr16676379523'UTRnovel0.16
COADchr1667628406Missense_MutationNAG519R0.18
COADchr1667620712Missense_MutationNAR368C0.59
COADchr1667611610Nonsense_MutationnovelK260*0.3
COADchr1667611016Frame_Shift_DelnovelM62Gfs*100.12
COADchr1667626704Missense_MutationNAA503S0.29
COADchr1667629503Missense_Mutationrs775874494R603C0.24
COADchr1667626587Missense_MutationNAE464K0.29
COADchr1667611406Frame_Shift_InsNAD194Rfs*360.38
COADchr1667628420Silentrs761420338Y523Y0.22
ESCAchr16676389543'UTRnovel0.28
ESCAchr16676381813'UTRnovel0.29
GBMchr1667626624Missense_MutationnovelF476Y0.07
GBMchr1667626638Missense_MutationnovelA481T0.07
GBMchr1667629468Missense_Mutationrs139828150T591M0.2
GBMchr1667611426SilentnovelQ198Q0.3
GBMchr1667628474Missense_MutationnovelH541Q0.55
HNSCchr1667626678Missense_MutationnovelR494L0.21
HNSCchr1667616848SilentnovelK352K0.09
HNSCchr1667621576Nonsense_Mutationrs769948988R448*0.15
HNSCchr1667611435Frame_Shift_InsNAT204Nfs*260.25
HNSCchr1667611574Missense_MutationnovelN248D0.25
HNSCchr1667611435Frame_Shift_InsNAT204Nfs*260.42
HNSCchr1667616853Missense_MutationNAS354F0.39
HNSCchr1667611338Frame_Shift_InsnovelA171Gfs*200.17
HNSCchr1667636797Nonsense_MutationnovelK649*0.38
HNSCchr1667616814Missense_MutationnovelR341H0.09
HNSCchr1667611270SilentnovelG146G0.35
HNSCchr1667616751Missense_MutationnovelR320H0.1
HNSCchr1667629446Frame_Shift_DelnovelG585Efs*420.25
HNSCchr1667629513Splice_SitenovelX607_splice0.13
HNSCchr1667626626Missense_MutationnovelH477Y0.16
HNSCchr1667616859Missense_MutationnovelC356F0.39
HNSCchr1667616829Missense_MutationnovelT346S0.23
HNSCchr1667636767Nonsense_MutationnovelQ639*0.11
KIRCchr1667626641Missense_MutationNAL482I0.47
KIRPchr1667611347Missense_Mutationrs761623880N172S0.39
LAMLchr1667610917SilentnovelR29R0.07
LAMLchr1667636832SilentnovelN660N0.07
LGGchr1667629507Missense_MutationNAS604C0.12
LGGchr16676379243'UTRnovel0.44
LIHCchr1667628471Missense_MutationNAM540I0.63
LIHCchr1667626606Missense_MutationnovelR470H0.32
LIHCchr1667616774Missense_MutationNAD328Y0.28
LIHCchr1667611435Frame_Shift_InsNAT204Nfs*260.39
LUADchr1667620733Missense_MutationNAG375R0.17
LUADchr1667628481Missense_Mutationrs112926498R544C0.39
LUADchr1667611991SilentNAT274T0.08
LUADchr1667636850Missense_MutationNAQ666H0.2
LUADchr1667626704Missense_MutationNAA503T0.7
LUADchr1667610971Missense_MutationNAG47W0.32
LUADchr1667628510SilentNAA553A0.12
LUADchr1667629505SilentNAR603R0.05
LUSCchr1667629464Missense_MutationnovelE590K0.15
LUSCchr1667611087Missense_MutationnovelE85D0.16
LUSCchr1667616842SilentnovelP350P0.6
LUSCchr1667628505Missense_MutationNAP552S0.34
LUSCchr1667628489Silentrs373624045H546H0.25
LUSCchr1667610971Missense_MutationnovelG47R0.12
LUSCchr1667637854SilentNAL722L0.1
LUSCchr1667611536Missense_MutationnovelG235V0.35
LUSCchr1667628540SilentNAT563T0.28
MESOchr1667612091Missense_MutationnovelL308V0.29
OVchr1667612042Missense_MutationNAE291D0.84
OVchr1667611558SilentnovelA242A0.12
OVchr1667611435Frame_Shift_InsNAT204Nfs*260.4
OVchr1667616861Missense_MutationNAD357N0.04
OVchr1667629442SilentNAG582G0.12
OVchr1667610933Missense_MutationnovelE34A0.2
PAADchr1667628490Missense_MutationnovelD547Y0.03
PAADchr1667611968Nonsense_MutationnovelQ267*0.08
PAADchr1667628463Missense_MutationnovelL538I0.19
PCPGchr1667611603Missense_MutationnovelI257M0.38
PRADchr1667620713Missense_MutationNAR368H0.06
PRADchr1667611511Missense_MutationnovelD227H0.25
READchr1667620722Missense_MutationNAR371H0.24
READchr1667610903Missense_MutationNAT24S0.39
READchr1667636785Missense_MutationnovelP645S0.09
READchr1667616807Missense_MutationnovelR339W0.44
READchr1667610851Missense_Mutationrs779609208E7K0.21
READchr1667629503Missense_Mutationrs775874494R603C0.28
SARCchr1667610834Translation_Start_SitenovelM1?0.45
SKCMchr1667616845SilentNAF351F0.08
SKCMchr1667636816Missense_MutationNAP655L0.26
SKCMchr1667610916Silentrs371652969R28R0.26
SKCMchr1667628505Missense_MutationNAP552S0.33
SKCMchr1667616853Missense_MutationNAS354F0.35
SKCMchr1667628501Silentrs373346637F550F0.34
SKCMchr1667616791SilentNAT333T0.15
SKCMchr1667611270SilentnovelG146G0.33
STADchr1667636803Missense_Mutationrs762060506R651W0.3
STADchr1667611372Frame_Shift_InsNAE182Gfs*90.13
STADchr1667626716Splice_SiteNAX506_splice0.19
STADchr1667611435Frame_Shift_InsNAT204Nfs*260.16
STADchr1667611435Frame_Shift_InsNAT204Nfs*260.26
STADchr1667611435Frame_Shift_InsNAT204Nfs*260.47
STADchr1667637752Frame_Shift_DelNAE691Sfs*300.22
STADchr1667620791Missense_MutationNAL394P0.11
STADchr1667612007Missense_MutationNAN280H0.1
STADchr1667611436Frame_Shift_DelNAT204Qfs*180.34
STADchr1667611435Frame_Shift_InsNAT204Nfs*260.31
STADchr1667628465Silentrs779124853L538L0.23
STADchr1667626648Missense_MutationnovelQ484P0.39
STADchr1667611436Frame_Shift_DelNAT204Qfs*180.23
STADchr1667611577Missense_Mutationrs747052464M249V0.59
STADchr1667611435Frame_Shift_InsnovelT204Kfs*190.44
STADchr1667621578Frame_Shift_Delrs34679888S450Vfs*610.18
STADchr1667628506Missense_MutationNAP552H0.07
STADchr1667611436Frame_Shift_DelNAT204Qfs*180.44
STADchr1667616808Missense_MutationNAR339Q0.17
STADchr1667611435Frame_Shift_InsNAT204Nfs*260.27
STADchr1667616773SilentNAC327C0.13
STADchr1667611436Frame_Shift_DelNAT204Qfs*180.14
STADchr1667628397Missense_MutationNAT516A0.12
STADchr1667612033Frame_Shift_DelnovelH288Qfs*220.29
STADchr1667637751Frame_Shift_InsnovelE691Rfs*50.19
STADchr1667626713Nonsense_MutationNAQ506*0.31
THCAchr1667629437Missense_MutationNAD581H0.09
THYMchr1667636852Splice_SiteNAX667_splice0.2
UCECchr1667611388Nonsense_MutationNAQ186*0.43
UCECchr1667611614Splice_SiteNAX261_splice0.47
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.55
UCECchr1667611283Frame_Shift_InsnovelP152Tfs*110.4
UCECchr1667628435Nonsense_MutationNAC528*0.29
UCECchr1667628420Nonsense_MutationNAY523*0.38
UCECchr1667611436Frame_Shift_DelNAT204Qfs*180.2
UCECchr1667628548Missense_MutationNAR566H0.46
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.27
UCECchr1667616817Missense_MutationNAR342H0.03
UCECchr1667620740Missense_MutationNAR377H0.48
UCECchr1667620743Missense_MutationNAP378L0.34
UCECchr1667610884Frame_Shift_DelNAG19Efs*430.45
UCECchr1667611372Frame_Shift_InsNAE182Gfs*90.48
UCECchr1667616814Missense_MutationnovelR341H0.47
UCECchr1667629421SilentnovelD575D0.18
UCECchr16676387353'UTRnovel0.38
UCECchr1667611236Frame_Shift_InsnovelA137Gfs*30.37
UCECchr1667611436Frame_Shift_DelNAT204Qfs*180.29
UCECchr1667612104Missense_MutationNAH312R0.33
UCECchr1667637776Silentrs371078024P696P0.27
UCECchr16676382973'UTRnovel0.57
UCECchr1667620704Missense_MutationNAK365T0.42
UCECchr1667611444Frame_Shift_DelnovelK206Pfs*150.33
UCECchr1667636765Missense_MutationnovelP638H0.45
UCECchr1667611095Missense_MutationnovelA88V0.17
UCECchr1667628550Missense_MutationnovelR567W0.33
UCECchr1667637751Frame_Shift_InsnovelE691Rfs*50.77
UCECchr16676380503'UTRnovel0.82
UCECchr1667621577Frame_Shift_InsnovelS450Kfs*20.24
UCECchr1667616819Missense_MutationNAY343H0.34
UCECchr1667620716Missense_MutationnovelH369R0.19
UCECchr1667610837Missense_MutationNAE2G0.27
UCECchr1667636743Nonsense_MutationNAE631*0.28
UCECchr1667620704Missense_MutationNAK365T0.28
UCECchr1667626661SilentNAS488S0.3
UCECchr1667620740Missense_MutationNAR377H0.51
UCECchr1667611451Missense_MutationNAT207P0.44
UCECchr1667636765Missense_MutationNAP638L0.27
UCECchr1667636696Frame_Shift_InsNAE616*0.48
UCECchr1667620739Missense_MutationNAR377C0.22
UCECchr1667629402Missense_MutationnovelT569I0.19
UCECchr1667610971Frame_Shift_DelnovelG48Vfs*140.52
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.4
UCECchr1667620739Missense_MutationNAR377C0.17
UCECchr1667611370Nonsense_MutationNAQ180*0.39
UCECchr1667626629Nonsense_MutationnovelE478*0.44
UCECchr1667610971Frame_Shift_DelnovelG48Vfs*140.41
UCECchr1667629397Splice_SiteNAX568_splice0.45
UCECchr1667611046Nonsense_MutationNAQ72*0.4
UCECchr1667611436Frame_Shift_DelNAT204Qfs*180.42
UCECchr1667621511Frame_Shift_DelnovelL427Yfs*200.45
UCECchr16676387283'UTRnovel0.31
UCECchr1667611495Frame_Shift_DelnovelD222Mfs*280.48
UCECchr1667621580Missense_MutationnovelK449T0.37
UCECchr16676388543'UTRnovel0.19
UCECchr16676379553'UTRnovel0.31
UCECchr1667620740Missense_MutationNAR377H0.09
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.32
UCECchr1667628406Missense_MutationNAG519R0.31
UCECchr1667628547Missense_MutationnovelR566C0.31
UCECchr1667610971Frame_Shift_DelnovelG48Vfs*140.48
UCECchr1667611469Missense_MutationnovelR213C0.34
UCECchr1667637776Silentrs371078024P696P0.32
UCECchr1667611436Frame_Shift_DelNAT204Qfs*180.22
UCECchr1667611265Nonsense_MutationNAE145*0.29
UCECchr1667616853Missense_MutationNAS354F0.24
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.22
UCECchr1667626692Nonsense_MutationnovelQ499*0.37
UCECchr1667611436Frame_Shift_DelNAT204Qfs*180.33
UCECchr1667611615Splice_SitenovelX261_splice0.6
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.36
UCECchr1667621477Missense_MutationnovelR415W0.25
UCECchr1667620739Missense_MutationNAR377C0.38
UCECchr1667621492Missense_MutationnovelG420C0.25
UCECchr1667616859Missense_MutationnovelC356Y0.38
UCECchr1667628395Missense_MutationNAR515H0.52
UCECchr1667629413Missense_MutationnovelH573Y0.39
UCECchr16676386163'UTRnovel0.28
UCECchr16675712585'UTRnovel0.39
UCECchr1667616773SilentNAC327C0.45
UCECchr1667621528Nonsense_MutationNAE432*0.29
UCECchr1667612103Missense_MutationnovelH312N0.37
UCECchr1667611436Frame_Shift_DelNAT204Qfs*180.45
UCECchr1667637751Frame_Shift_InsnovelE691Rfs*50.49
UCECchr1667620743Missense_MutationNAP378L0.39
UCECchr1667611384Frame_Shift_InsNAQ186Pfs*50.43
UCECchr1667611436Frame_Shift_DelNAT204Qfs*180.45
UCECchr1667611286Frame_Shift_DelnovelM153*0.37
UCECchr1667620739Missense_MutationNAR377C0.42
UCECchr1667611599Frame_Shift_DelNAI257Kfs*110.43
UCECchr1667612109Frame_Shift_InsNAG318Qfs*160.45
UCECchr1667612109Frame_Shift_InsNAG318Qfs*160.33
UCECchr1667620778Frame_Shift_InsNAD390Gfs*60.44
UCECchr1667621576Nonsense_Mutationrs769948988R448*0.14
UCECchr1667611237Frame_Shift_DelNAA137Lfs*170.42
UCECchr1667616816Missense_MutationNAR342C0.41
UCECchr1667611147SilentnovelE105E0.32
UCECchr1667616820Missense_MutationnovelY343C0.35
UCECchr16676384823'UTRnovel0.37
UCECchr1667620743Missense_MutationNAP378L0.29
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.34
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.21
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.36
UCECchr1667611613Missense_MutationnovelG261C0.3
UCECchr1667616862Frame_Shift_InsNAY358Lfs*510.23
UCECchr16676380233'UTRnovel0.3
UCECchr1667611436Frame_Shift_DelNAT204Qfs*180.48
UCECchr1667626651Missense_MutationNAH485R0.06
UCECchr1667616853Missense_MutationNAS354F0.41
UCECchr1667626606Frame_Shift_DelnovelR470Lfs*410.37
UCECchr1667636767Nonsense_MutationnovelQ639*0.34
UCECchr1667611423Nonsense_MutationNAY197*0.38
UCECchr1667611424Nonsense_MutationNAQ198*0.38
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.52
UCECchr1667611349Nonsense_MutationnovelG173*0.24
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.38
UCECchr1667636767Nonsense_MutationnovelQ639*0.37
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.6
UCECchr16676379523'UTRnovel0.26
UCECchr1667636747Frame_Shift_DelNAI632Mfs*100.52
UCECchr1667616807Missense_MutationnovelR339W0.54
UCECchr1667620722Missense_MutationNAR371H0.48
UCECchr1667621477Missense_MutationnovelR415W0.34
UCECchr1667628465Silentrs779124853L538L0.48
UCECchr1667621576Nonsense_Mutationrs769948988R448*0.44
UCECchr1667636852Splice_SiteNAX667_splice0.22
UCECchr16676389303'UTRnovel0.16
UCECchr1667620739Missense_MutationNAR377C0.7
UCECchr1667629506Frame_Shift_DelNAS604Lfs*270.36
UCECchr16676386483'UTRnovel0.46
UCECchr1667611367Nonsense_MutationNAE179*0.21
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.44
UCECchr16676379243'UTRnovel0.23
UCECchr1667611166Nonsense_MutationNAE112*0.19
UCECchr16676384113'UTRnovel0.23
UCECchr1667610930Missense_MutationnovelQ33R0.28
UCECchr16676386863'UTRnovel0.42
UCECchr1667611338Frame_Shift_InsnovelA171Gfs*200.23
UCECchr1667611509Missense_MutationNAY226C0.3
UCECchr1667628378SilentnovelH509H0.35
UCECchr1667616865Missense_MutationnovelY358C0.07
UCECchr1667637751Frame_Shift_InsnovelE691Rfs*50.32
UCECchr1667629464Nonsense_MutationNAE590*0.17
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.26
UCECchr1667611436Frame_Shift_DelNAT204Qfs*180.4
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.36
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.31
UCECchr1667621576Nonsense_Mutationrs769948988R448*0.4
UCECchr1667620740Missense_MutationNAR377H0.07
UCECchr1667612098Missense_MutationnovelR310M0.29
UCECchr1667626566Nonsense_MutationNAR457*0.41
UCECchr1667621572Frame_Shift_DelnovelA447Vfs*610.43
UCECchr1667620739Missense_MutationNAR377C0.27
UCECchr1667628395Missense_MutationNAR515H0.38
UCECchr1667637786Nonsense_MutationnovelE700*0.44
UCECchr1667611370Nonsense_MutationNAQ180*0.37
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.38
UCECchr1667612109Frame_Shift_InsNAG318Qfs*160.26
UCECchr1667626566Nonsense_MutationNAR457*0.2
UCECchr1667621576Nonsense_Mutationrs769948988R448*0.15
UCECchr1667611166Nonsense_MutationNAE112*0.57
UCECchr1667610971Frame_Shift_DelnovelG48Vfs*140.43
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.54
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.43
UCECchr1667621576Nonsense_Mutationrs769948988R448*0.3
UCECchr1667621577Missense_MutationnovelR448Q0.32
UCECchr1667626713Nonsense_MutationNAQ506*0.41
UCECchr1667611163Nonsense_MutationnovelG111*0.36
UCECchr1667610923Frame_Shift_DelnovelG32Afs*300.45
UCECchr16675712585'UTRnovel0.29
UCECchr1667626553Splice_SitenovelX453_splice0.27
UCECchr1667637778Missense_MutationnovelA697V0.39
UCECchr1667611320Missense_MutationNAG163E0.29
UCECchr1667611435Frame_Shift_InsNAT204Nfs*260.23
UCECchr1667621576Nonsense_Mutationrs769948988R448*0.16
UCECchr1667628400Missense_MutationNAH517Y0.22
UCECchr1667621577Frame_Shift_InsnovelS450Kfs*20.41
UCECchr1667628548Missense_MutationNAR566H0.21
UCECchr16676386263'UTRrs5572534950.48
UCECchr1667612109Frame_Shift_InsNAG318Qfs*160.35
UCECchr1667611969Missense_MutationnovelQ267P0.33
UCECchr1667628465Silentrs779124853L538L0.15
UCECchr1667626566Nonsense_MutationNAR457*0.38
UCECchr1667616764Nonsense_MutationnovelC324*0.32
UCECchr1667628449Missense_MutationnovelR533H0.46
UCSchr1667616751Missense_MutationnovelR320H0.46
UCSchr1667611209Frame_Shift_DelnovelA127Pfs*40.47
UCSchr1667611229Nonsense_MutationnovelE133*0.31

Copy Number Variations (CNVs)
CancerTypeFreq Q-value
BLCAAMP0.19120.063591
CHOLDEL0.16670.23475
LAMLDEL0.03140.0010312
TGCTAMP0.120.035574
UCECDEL0.28394.7164e-05

Survival Analysis
CancerP-value Q-value
THYM0.0014

Kaplan-Meier Survival Analysis

KIRC0.00013

Kaplan-Meier Survival Analysis

PRAD0.044

Kaplan-Meier Survival Analysis

PAAD0.017

Kaplan-Meier Survival Analysis

BLCA0.017

Kaplan-Meier Survival Analysis

LIHC0.011

Kaplan-Meier Survival Analysis

LGG0.00013

Kaplan-Meier Survival Analysis

UVM0.019

Kaplan-Meier Survival Analysis

Drugs

Select Dataset :


Input Drug :


Input Cell Line :


Eesembl ID



Cell lines and drugs in GSE70138 or GSE92742

  • Description
  • RBPome
  • Literatures
  • Expression
  • Transcripts
  • Gene Model
  • Phenotypes
  • PPI
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000102974 (Gene tree)
Gene ID
10664
Gene Symbol
CTCF
Alias
N
Full Name
CCCTC-binding factor
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Plus strand
Length
76,779 bases
Position
chr16:67,562,407-67,639,185
Accession
13723
RBP type
non-canonical RBP
Summary
This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & MCF72018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity
PIDTitleArticle TimeAuthorDoi
26549029CTCF cooperates with noncoding RNA MYCNOS to promote neuroblastoma progression through facilitating MYCN expression.Oncogene2016 Jul 7Zhao Xdoi: 10.1038/onc.2015.422
19826084A wave of nascent transcription on activated human genes.Proc Natl Acad Sci U S A2009 Oct 27Wada Ydoi: 10.1073/pnas.0902573106
24696455CTCF regulates the human p53 gene through direct interaction with its natural antisense transcript, Wrap53.Genes Dev2014 Apr 1Saldana-Meyer Rdoi: 10.1101/gad.236869.113.
23898036Deep sequencing of the murine IgH repertoire reveals complex regulation of nonrandom V gene rearrangement frequencies.J Immunol2013 Sep 1Choi NMdoi: 10.4049/jimmunol.1301279
20966046Mediation of CTCF transcriptional insulation by DEAD-box RNA-binding protein p68 and steroid receptor RNA activator SRA.Genes Dev2010 Nov 15Yao Hdoi: 10.1101/gad.1967810
23791181Jpx RNA activates Xist by evicting CTCF.Cell2013 Jun 20Sun Sdoi: 10.1016/j.cell.2013.05.028.
31291573Three-Dimensional Genomic Structure and Cohesin Occupancy Correlate with Transcriptional Activity during Spermatogenesis.Cell Rep2019 Jul 9Vara Cdoi: 10.1016/j.celrep.2019.06.037.
10906122Physical and functional interaction between two pluripotent proteins, the Y-box DNA/RNA-binding factor, YB-1, and the multivalent zinc finger factor, CTCF.J Biol Chem2000 Sep 22Chernukhin IV-
21111075Long-range DNA interactions are specifically altered by locked nucleic acid-targeting of a CTCF binding site.Biochim Biophys Acta2011 JanLing JQdoi: 10.1016/j.bbagrm.2010.11.004
25578877Locus-specific targeting to the X chromosome revealed by the RNA interactome of CTCF.Mol Cell2015 Jan 22Kung JTdoi: 10.1016/j.molcel.2014.12.006
29793448Putative bovine topological association domains and CTCF binding motifs can reduce the search space for causative regulatory variants of complex traits.BMC Genomics2018 May 24Wang Mdoi: 10.1186/s12864-018-4800-0.
10625678An element in the region responsible for premature termination of transcription mediates repression of c-myc gene expression by thyroid hormone in neuroblastoma cells.J Biol Chem2000 Jan 14Perez-Juste G-
25837375The alternative role of DNA methylation in splicing regulation.Trends Genet2015 MayLev Maor Gdoi: 10.1016/j.tig.2015.03.002
29572403Genome-Wide Mapping of DNA Accessibility and Binding Sites for CREB and C/EBPβ in Vasopressin-Sensitive Collecting Duct Cells.J Am Soc Nephrol2018 MayJung HJdoi: 10.1681/ASN.2017050545
21059229CTCF regulates the local epigenetic state of ribosomal DNA repeats.Epigenetics Chromatin2010 Nov 8van de Nobelen Sdoi: 10.1186/1756-8935-3-19.
23933634CTCF depletion alters chromatin structure and transcription of myeloid-specific factors.J Mol Cell Biol2013 OctOuboussad Ldoi: 10.1093/jmcb/mjt023
19843608Inactive X chromosome-specific histone H3 modifications and CpG hypomethylation flank a chromatin boundary between an X-inactivated and an escape gene.Nucleic Acids Res2009 DecGoto Ydoi: 10.1093/nar/gkp860.
21964334CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing.Nature2011 Nov 3Shukla Sdoi: 10.1038/nature10442.
21895576CTCF function is modulated by neighboring DNA binding factors.Biochem Cell Biol2011 OctWeth Odoi: 10.1139/o11-033
24659782Transcription of angiogenin and ribonuclease 4 is regulated by RNA polymerase III elements and a CCCTC binding factor (CTCF)-dependent intragenic chromatin loop.J Biol Chem2014 May 2Sheng Jdoi: 10.1074/jbc.M114.551762
23884423Ribosomal RNA gene transcription mediated by the master genome regulator protein CCCTC-binding factor (CTCF) is negatively regulated by the condensin complex.J Biol Chem2013 Sep 6Huang Kdoi: 10.1074/jbc.M113.486175
29698677Long noncoding RNA HOTTIP cooperates with CCCTC-binding factor to coordinate HOXA gene expression.Biochem Biophys Res Commun2018 Jun 12Wang Fdoi: 10.1016/j.bbrc.2018.04.173
29755673Role of epigenetic factors in the selection of the alternative splicing isoforms of human KRAS in colorectal cancer cell lines.Oncotarget2018 Apr 17Riffo-Campos aLdoi: 10.18632/oncotarget.25016
300179063D genomic regulation of lncRNA and Xist in X chromosome.Semin Cell Dev Biol2019 JunYan Fdoi: 10.1016/j.semcdb.2018.07.013
30940740CTCF: a Swiss-army knife for genome organization and transcription regulation.Essays Biochem2019 Apr 23Braccioli Ldoi: 10.1042/EBC20180069
8649389An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes.Mol Cell Biol1996 JunFilippova GN-
16285929Antisense transcription and heterochromatin at the DM1 CTG repeats are constrained by CTCF.Mol Cell2005 Nov 11Cho DH-
23416946Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures.Nat Struct Mol Biol2013 MarNaughton Cdoi: 10.1038/nsmb.2509
17512414High-resolution profiling of histone methylations in the human genome.Cell2007 May 18Barski A-
22090374Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells.Genome Res2012 JanLee BKdoi: 10.1101/gr.127597.111
21916612The role of CTCF in coordinating the expression of single gene loci.Biochem Cell Biol2011 OctGillen AEdoi: 10.1139/o11-040
21930510Genome-wide prediction and analysis of human chromatin boundary elements.Nucleic Acids Res2012 JanWang Jdoi: 10.1093/nar/gkr750
21304052Estrogen-mediated epigenetic repression of the imprinted gene cyclin-dependent kinase inhibitor 1C in breast cancer cells.Carcinogenesis2011 JunRodriguez BAdoi: 10.1093/carcin/bgr017
23192870CTCF regulates Kaposi's sarcoma-associated herpesvirus latency transcription by nucleosome displacement and RNA polymerase programming.J Virol2013 FebKang Hdoi: 10.1128/JVI.02283-12
25646466Genome-wide targeting of the epigenetic regulatory protein CTCF to gene promoters by the transcription factor TFII-I.Proc Natl Acad Sci U S A2015 Feb 17Pena-Hernandez Rdoi: 10.1073/pnas.1416674112
28145452Testis-specific transcriptional regulators selectively occupy BORIS-bound CTCF target regions in mouse male germ cells.Sci Rep2017 Feb 1Rivero-Hinojosa Sdoi: 10.1038/srep41279.
24321385Cohesin and CTCF differentially regulate spatiotemporal runx1 expression during zebrafish development.Biochim Biophys Acta2014 JanMarsman Jdoi: 10.1016/j.bbagrm.2013.11.007
24059801DNA methylation and differentiation: silencing, upregulation and modulation of gene expression.Epigenomics2013Ehrlich Mdoi: 10.2217/epi.13.43.
23986576The open chromatin landscape of Kaposi's sarcoma-associated herpesvirus.J Virol2013 NovHilton IBdoi: 10.1128/JVI.01685-13
23533622A NF-kB-dependent dual promoter-enhancer initiates the lipopolysaccharide-mediated transcriptional activation of the chicken lysozyme in macrophages.PLoS One2013Witham Jdoi: 10.1371/journal.pone.0059389
26347501Long Noncoding RNA CUDR Regulates HULC and β-Catenin to Govern Human Liver Stem Cell Malignant Differentiation.Mol Ther2015 DecGui Xdoi: 10.1038/mt.2015.166
26686651CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription.Cell2015 Dec 17Tang Zdoi: 10.1016/j.cell.2015.11.024
26938874Role of CTCF in Regulating SLC45A3-ELK4 Chimeric RNA.PLoS One2016 Mar 3Qin Fdoi: 10.1371/journal.pone.0150382
26216945MIR retrotransposon sequences provide insulators to the human genome.Proc Natl Acad Sci U S A2015 Aug 11Wang Jdoi: 10.1073/pnas.1507253112
28938092CTCF-Mediated Enhancer-Promoter Interaction Is a Critical Regulator of Cell-to-Cell Variation of Gene Expression.Mol Cell2017 Sep 21Ren Gdoi: 10.1016/j.molcel.2017.08.026.
29199022CTCF-Mediated Chromatin Loops between Promoter and Gene Body Regulate Alternative Splicing across Individuals.Cell Syst2017 Dec 27Ruiz-Velasco Mdoi: 10.1016/j.cels.2017.10.018
29235471CTCF driven TERRA transcription facilitates completion of telomere DNA replication.Nat Commun2017 Dec 13Beishline Kdoi: 10.1038/s41467-017-02212-w.
29654311A TAD boundary is preserved upon deletion of the CTCF-rich Firre locus.Nat Commun2018 Apr 13Barutcu ARdoi: 10.1038/s41467-018-03614-0.
29712779Dopamine Triggers CTCF-Dependent Morphological and Genomic Remodeling of Astrocytes.J Neurosci2018 May 23Galloway Adoi: 10.1523/JNEUROSCI.3349-17.2018
30955885Antisense lncRNA Transcription Mediates DNA Demethylation to Drive Stochastic Protocadherin α Promoter Choice.Cell2019 Apr 18Canzio Ddoi: 10.1016/j.cell.2019.03.008
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000401394CTCF-2022797-ENSP00000384707399 (aa)-P49711
ENST00000642847CTCF-2061174-ENSP00000495923135 (aa)-A0A2R8Y6Z6
ENST00000646566CTCF-2163952--- (aa)--
ENST00000645306CTCF-2123662XM_017022869ENSP00000495218725 (aa)XP_016878358A0A2R8YFL0
ENST00000644950CTCF-2112833--- (aa)--
ENST00000646771CTCF-2173706XM_005255775ENSP00000494443725 (aa)XP_005255832A0A2R8YFL0
ENST00000643892CTCF-2083783-ENSP00000494358638 (aa)-A0A2R8Y595
ENST00000646076CTCF-2153989-ENSP00000494538727 (aa)-P49711
ENST00000644753CTCF-2093713XM_017022868ENSP00000493495727 (aa)XP_016878357P49711
ENST00000644852CTCF-210734-ENSP00000495115163 (aa)-A0A2R8Y6C1
ENST00000642819CTCF-2053975-ENSP00000494408727 (aa)-P49711
ENST00000642420CTCF-2042131--- (aa)--
ENST00000645409CTCF-2134271--- (aa)--
ENST00000264010CTCF-2013941-ENSP00000264010727 (aa)-P49711
ENST00000566078CTCF-2031302--- (aa)--
ENST00000645699CTCF-2143521-ENSP00000495348727 (aa)-P49711
ENST00000642943CTCF-2074802--- (aa)--
Gene Model
Click here to download ENSG00000102974's gene model file
Phenotypes
ensgIDTraitpValuePubmed ID
ENSG00000102974Cholesterol, HDL2.203e-00819060910
ENSG00000102974Cholesterol, HDL7.721e-00619060910
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000102974's network

* RBP PPI network refers to all genes directly bind to RBP
Orthologs identified by RBPome
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000102974CTCF10099.387ENSMUSG00000005698Ctcf10097.962Mus_musculus
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0000122negative regulation of transcription by RNA polymerase II8649389.IDAProcess
GO:0000775chromosome, centromeric region18550811.26321640.IDAComponent
GO:0000793condensed chromosome16107875.IDAComponent
GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding8649389.IDAFunction
GO:0000981DNA-binding transcription factor activity, RNA polymerase II-specific-ISAFunction
GO:0000981DNA-binding transcription factor activity, RNA polymerase II-specific19274049.NASFunction
GO:0001227DNA-binding transcription repressor activity, RNA polymerase II-specific8649389.IDAFunction
GO:0001228DNA-binding transcription activator activity, RNA polymerase II-specific-IEAFunction
GO:0003700DNA-binding transcription factor activity21873635.IBAFunction
GO:0003700DNA-binding transcription factor activity8649389.9591631.IDAFunction
GO:0003714transcription corepressor activity8649389.TASFunction
GO:0005515protein binding19505873.19536159.24725430.24937458.25416956.26321640.IPIFunction
GO:0005634nucleus9407128.28319062.IDAComponent
GO:0005654nucleoplasm21873635.IBAComponent
GO:0005654nucleoplasm16107875.16595548.IDAComponent
GO:0005730nucleolus16595548.IDAComponent
GO:0006306DNA methylation-IEAProcess
GO:0006349regulation of gene expression by genetic imprinting-IEAProcess
GO:0007059chromosome segregation-IEAProcess
GO:0008270zinc ion binding8649389.TASFunction
GO:0008285negative regulation of cell proliferation28319062.IMPProcess
GO:0010216maintenance of DNA methylation-IEAProcess
GO:0010628positive regulation of gene expression18347100.IMPProcess
GO:0016584nucleosome positioning18654629.IDAProcess
GO:0031060regulation of histone methylation-IEAProcess
GO:0035065regulation of histone acetylation-IEAProcess
GO:0040029regulation of gene expression, epigenetic16815976.IMPProcess
GO:0040030regulation of molecular function, epigenetic16815976.IMPProcess
GO:0043035chromatin insulator sequence binding17827499.IDAFunction
GO:0043565sequence-specific DNA binding17827499.IDAFunction
GO:0044212transcription regulatory region DNA binding21873635.IBAFunction
GO:0044212transcription regulatory region DNA binding18413740.IDAFunction
GO:0045892negative regulation of transcription, DNA-templated8649389.18413740.IDAProcess
GO:0045893positive regulation of transcription, DNA-templated9407128.IDAProcess
GO:0045893positive regulation of transcription, DNA-templated19322193.IMPProcess
GO:0045944positive regulation of transcription by RNA polymerase II21873635.IBAProcess
GO:0070602regulation of centromeric sister chromatid cohesion18550811.NASProcess
GO:0071459protein localization to chromosome, centromeric region26321640.IMPProcess
To top

Copyright © , Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.

Any comment and suggestion, please contact us