EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
27477906	ZMYND8 Reads the Dual Histone Mark H3K4me1-H3K14ac to Antagonize the Expression of Metastasis-Linked Genes.	Mol Cell	2016 Aug 4	Li N	doi: 10.1016/j.molcel.2016.06.035
28432260	Dual histone reader ZMYND8 inhibits cancer cell invasion by positively regulating epithelial genes.	Biochem J	2017 May 19	Basu M	doi: 10.1042/BCJ20170223.
25117453	Zinc finger MYND-type containing 8 promotes tumour angiogenesis via induction of vascular endothelial growth factor-A expression.	FEBS Lett	2014 Sep 17	Kuroyanagi J	doi: 10.1016/j.febslet.2014.07.033

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr20	47236497	Silent	novel	I875I	0.47
ACC	chr20	47347872	Missense_Mutation	novel	I3M	0.31
BLCA	chr20	47221460	Nonsense_Mutation	novel	Q1071*	0.64
BLCA	chr20	47238929	Missense_Mutation	novel	P812T	0.1
BLCA	chr20	47224380	Missense_Mutation	NA	Y1045H	0.21
BLCA	chr20	47239090	Missense_Mutation	rs780491504	P758L	0.06
BLCA	chr20	47246187	Nonsense_Mutation	novel	S682*	0.46
BLCA	chr20	47221407	Silent	NA	G1088G	0.36
BLCA	chr20	47319078	Intron	novel		0.27
BLCA	chr20	47276717	Missense_Mutation	novel	F339L	0.14
BLCA	chr20	47283613	Silent	NA	L260L	0.13
BLCA	chr20	47298775	Missense_Mutation	NA	R116I	0.62
BLCA	chr20	47291807	Missense_Mutation	novel	T197A	0.52
BLCA	chr20	47298929	Missense_Mutation	novel	P65S	0.2
BLCA	chr20	47291837	Nonsense_Mutation	novel	E187*	0.26
BLCA	chr20	47276530	Missense_Mutation	NA	D402H	0.25
BLCA	chr20	47283637	Missense_Mutation	novel	I252M	0.08
BLCA	chr20	47294764	Missense_Mutation	NA	E137K	0.29
BLCA	chr20	47221463	Nonsense_Mutation	NA	Q1070*	0.21
BLCA	chr20	47246303	Missense_Mutation	NA	E643D	0.22
BLCA	chr20	47224501	Silent	NA	I1004I	0.34
BLCA	chr20	47347861	Missense_Mutation	NA	S7F	0.36
BLCA	chr20	47276742	Missense_Mutation	novel	S331C	0.16
BLCA	chr20	47236395	Silent	novel	V909V	0.05
BRCA	chr20	47356699	5'Flank	novel		0.25
BRCA	chr20	47262341	Missense_Mutation	rs143023321	T503M	0.37
BRCA	chr20	47238988	Missense_Mutation	NA	P792L	0.24
BRCA	chr20	47276758	Missense_Mutation	novel	K326E	0.05
BRCA	chr20	47227221	Missense_Mutation	NA	E980K	0.24
BRCA	chr20	47246328	Frame_Shift_Del	NA	*K635Sfs14**	0.14
BRCA	chr20	47210497	3'UTR	novel		0.38
BRCA	chr20	47236399	Missense_Mutation	NA	S908L	0.13
BRCA	chr20	47249368	Missense_Mutation	NA	L545F	0.18
BRCA	chr20	47238942	Silent	NA	P807P	0.24
BRCA	chr20	47249436	Missense_Mutation	novel	R522Q	0.07
BRCA	chr20	47310171	Missense_Mutation	NA	R20I	0.23
BRCA	chr20	47236353	Silent	rs149945102	A923A	0.41
BRCA	chr20	47262367	Missense_Mutation	NA	F494L	0.2
BRCA	chr20	47246328	Frame_Shift_Del	NA	*K635Sfs14**	0.08
CESC	chr20	47227221	Missense_Mutation	NA	E980K	0.44
CESC	chr20	47224452	Missense_Mutation	NA	E1021K	0.37
CESC	chr20	47310153	Missense_Mutation	novel	P26Q	0.08
CESC	chr20	47209743	3'UTR	novel		0.22
CESC	chr20	47246423	In_Frame_Ins	novel	I603delinsMA	0.07
CESC	chr20	47246425	Frame_Shift_Ins	novel	*I603Ffs5**	0.03
CESC	chr20	47224385	Missense_Mutation	novel	T1043I	0.07
CESC	chr20	47294764	Missense_Mutation	NA	E137Q	0.24
CESC	chr20	47318978	Intron	NA		0.66
CESC	chr20	47239066	Missense_Mutation	novel	S766F	0.05
CHOL	chr20	47210267	3'UTR	novel		0.37
COAD	chr20	47210665	3'UTR	novel		0.46
COAD	chr20	47224409	Missense_Mutation	NA	A1035V	0.44
COAD	chr20	47246171	Missense_Mutation	NA	K687N	0.38
COAD	chr20	47276367	Missense_Mutation	rs748590284	S456L	0.22
COAD	chr20	47249397	Missense_Mutation	NA	S535L	0.26
COAD	chr20	47236480	Missense_Mutation	rs373435522	T881M	0.19
COAD	chr20	47246512	Missense_Mutation	novel	N574H	0.35
COAD	chr20	47227217	Missense_Mutation	novel	M981T	0.04
COAD	chr20	47276674	Missense_Mutation	rs746337186	R354C	0.41
COAD	chr20	47356732	5'Flank	novel		0.24
COAD	chr20	47356694	5'Flank	novel		0.28
COAD	chr20	47246099	Silent	rs141781562	S711S	0.33
COAD	chr20	47224536	Missense_Mutation	rs541703317	R993W	0.15
COAD	chr20	47246328	Frame_Shift_Del	NA	*K635Sfs14**	0.17
COAD	chr20	47238666	Intron	novel		0.28
COAD	chr20	47246284	Frame_Shift_Del	NA	*S650Afs37**	0.3
COAD	chr20	47224498	Silent	novel	A1005A	0.09
COAD	chr20	47220325	Splice_Site	NA	X1120_splice	0.22
COAD	chr20	47238837	Missense_Mutation	novel	Q842H	0.38
COAD	chr20	47238838	Missense_Mutation	novel	Q842R	0.35
COAD	chr20	47276569	Missense_Mutation	novel	A389T	0.16
COAD	chr20	47276629	Missense_Mutation	novel	Y369H	0.05
COAD	chr20	47236352	Missense_Mutation	rs371544404	A924T	0.37
COAD	chr20	47276576	Silent	rs375904065	A386A	0.32
COAD	chr20	47239114	Missense_Mutation	novel	T750M	0.45
COAD	chr20	47276453	Silent	rs112232405	S427S	0.38
COAD	chr20	47227221	Missense_Mutation	NA	E980K	0.29
COAD	chr20	47276409	Missense_Mutation	NA	T442M	0.12
COAD	chr20	47246173	Missense_Mutation	NA	K687Q	0.29
COAD	chr20	47246195	Silent	NA	A679A	0.1
COAD	chr20	47224424	Missense_Mutation	NA	N1030I	0.53
COAD	chr20	47246098	Missense_Mutation	rs772025610	E712K	0.25
COAD	chr20	47290270	Missense_Mutation	rs762314721	A202V	0.49
COAD	chr20	47212652	Intron	NA		0.5
COAD	chr20	47224428	Missense_Mutation	NA	A1029T	0.5
ESCA	chr20	47209860	3'UTR	novel		0.2
ESCA	chr20	47238339	Intron	novel		0.25
ESCA	chr20	47294702	Silent	novel	L157L	0.11
ESCA	chr20	47236488	Silent	novel	S878S	0.11
GBM	chr20	47236457	Missense_Mutation	novel	S889G	0.33
GBM	chr20	47246312	Missense_Mutation	novel	N640K	0.07
GBM	chr20	47276479	Frame_Shift_Ins	novel	*G419Rfs33**	0.07
GBM	chr20	47229761	Missense_Mutation	novel	L948I	0.14
GBM	chr20	47249396	Silent	rs111541617	S535S	0.35
GBM	chr20	47210815	Frame_Shift_Del	novel	*S1170Afs52**	0.25
GBM	chr20	47291829	Silent	novel	I189I	0.04
GBM	chr20	47262400	Frame_Shift_Del	novel	*A484Qfs33**	0.08
GBM	chr20	47210674	3'UTR	novel		0.25
GBM	chr20	47227268	Missense_Mutation	novel	R964M	0.12
GBM	chr20	47238834	Missense_Mutation	novel	Q843H	0.29
GBM	chr20	47246155	Frame_Shift_Ins	novel	*K693Gfs24**	0.04
GBM	chr20	47239089	Silent	rs770713974	P758P	0.19
HNSC	chr20	47236399	Missense_Mutation	NA	S908L	0.11
HNSC	chr20	47210810	Missense_Mutation	novel	T1171M	0.12
HNSC	chr20	47246267	Silent	rs771468548	S655S	0.16
HNSC	chr20	47298907	Missense_Mutation	novel	P72L	0.37
HNSC	chr20	47239012	Missense_Mutation	rs369116353	T784M	0.28
HNSC	chr20	47298906	Silent	novel	P72P	0.1
HNSC	chr20	47246204	Silent	rs143651717	S676S	0.14
KIRC	chr20	47224443	Missense_Mutation	NA	K1024E	0.26
KIRC	chr20	47224417	Silent	novel	K1032K	0.21
KIRP	chr20	47249373	Missense_Mutation	novel	V543G	0.31
LAML	chr20	47276569	Missense_Mutation	novel	A389T	0.03
LAML	chr20	47212709	Intron	novel		0.14
LIHC	chr20	47276552	Silent	novel	Q394Q	0.26
LIHC	chr20	47291835	Silent	NA	E187E	0.38
LUAD	chr20	47298865	Missense_Mutation	novel	R86P	0.18
LUAD	chr20	47356705	5'Flank	novel		0.16
LUAD	chr20	47224349	Missense_Mutation	novel	W1055L	0.23
LUAD	chr20	47283603	Frame_Shift_Del	novel	*Q264Kfs22**	0.19
LUAD	chr20	47291875	Missense_Mutation	NA	Q174L	0.12
LUAD	chr20	47221396	Missense_Mutation	NA	S1092I	0.31
LUAD	chr20	47283616	Frame_Shift_Del	novel	C255*	0.08
LUAD	chr20	47276472	Missense_Mutation	NA	G421V	0.11
LUAD	chr20	47290249	Missense_Mutation	NA	C209F	0.13
LUAD	chr20	47224546	Missense_Mutation	rs529642788	M989I	0.2
LUAD	chr20	47236510	Missense_Mutation	novel	Q871L	0.29
LUAD	chr20	47246257	Missense_Mutation	novel	D659Y	0.47
LUAD	chr20	47356688	5'Flank	novel		0.09
LUAD	chr20	47291846	Missense_Mutation	NA	D184Y	0.59
LUAD	chr20	47276330	Silent	rs778893637	F468F	0.2
LUAD	chr20	47283637	Silent	rs768524845	I252I	0.23
LUAD	chr20	47246275	Missense_Mutation	NA	P653A	0.22
LUAD	chr20	47276664	Missense_Mutation	novel	F357C	0.43
LUSC	chr20	47347872	Silent	NA	I3I	0.15
LUSC	chr20	47236476	Silent	NA	S882S	0.34
LUSC	chr20	47276320	Missense_Mutation	NA	S472G	0.64
LUSC	chr20	47210642	3'UTR	novel		0.13
LUSC	chr20	47236392	Silent	rs779785588	N910N	0.1
LUSC	chr20	47246448	Missense_Mutation	novel	S595L	0.11
LUSC	chr20	47276537	Silent	novel	L399L	0.16
LUSC	chr20	47276760	Missense_Mutation	novel	S325C	0.21
LUSC	chr20	47224341	Missense_Mutation	novel	H1058Y	0.12
LUSC	chr20	47238698	Intron	novel		0.31
LUSC	chr20	47276314	Missense_Mutation	NA	A474S	0.41
LUSC	chr20	47236437	Silent	novel	L895L	0.9
LUSC	chr20	47298845	Frame_Shift_Del	novel	*V93Ffs23**	0.39
LUSC	chr20	47229806	Frame_Shift_Ins	novel	*M933Pfs7**	0.09
LUSC	chr20	47239115	Missense_Mutation	novel	T750S	0.04
MESO	chr20	47276757	Missense_Mutation	NA	K326R	0.57
OV	chr20	47319059	Intron	novel		0.14
OV	chr20	47210859	Frame_Shift_Ins	novel	*D1155Pfs68**	0.03
OV	chr20	47262418	Silent	NA	A477A	0.48
OV	chr20	47262399	Missense_Mutation	NA	A484T	0.66
OV	chr20	47318944	Intron	novel		0.16
OV	chr20	47224357	Missense_Mutation	novel	Q1052H	0.05
OV	chr20	47224359	Missense_Mutation	novel	Q1052K	0.04
OV	chr20	47276466	Missense_Mutation	rs568551781	R423Q	0.09
OV	chr20	47224338	Missense_Mutation	novel	M1059L	0.09
OV	chr20	47224543	Silent	rs778041374	A990A	0.55
OV	chr20	47318852	Intron	novel		0.63
OV	chr20	47210533	3'UTR	novel		0.14
PAAD	chr20	47210832	Missense_Mutation	rs750833798	D1164N	0.1
PAAD	chr20	47221344	Silent	rs762469626	T1109T	0.19
PAAD	chr20	47227278	Missense_Mutation	rs749035523	R961C	0.15
PAAD	chr20	47238882	Silent	rs190889041	T827T	0.17
PAAD	chr20	47246171	Missense_Mutation	NA	K687N	0.08
PAAD	chr20	47291867	Missense_Mutation	NA	V177I	0.04
PCPG	chr20	47282126	Missense_Mutation	NA	A305V	0.07
PCPG	chr20	47282127	Missense_Mutation	novel	A305T	0.07
READ	chr20	47287259	Silent	rs376502713	A238A	0.27
READ	chr20	47210879	Missense_Mutation	NA	K1148T	0.23
READ	chr20	47246502	Missense_Mutation	rs760696325	S577L	0.04
READ	chr20	47221412	Nonsense_Mutation	NA	Q1087*	0.11
READ	chr20	47210723	3'UTR	novel		0.38
READ	chr20	47290263	Missense_Mutation	novel	K204N	0.31
SARC	chr20	47238783	Silent	novel	R860R	0.39
SARC	chr20	47282139	Missense_Mutation	novel	G301R	0.36
SARC	chr20	47262412	Silent	novel	T479T	0.27
SARC	chr20	47282156	Missense_Mutation	novel	A295D	0.08
SKCM	chr20	47249287	Missense_Mutation	novel	G572S	0.18
SKCM	chr20	47239005	Silent	rs771098315	T786T	0.47
SKCM	chr20	47246149	Missense_Mutation	novel	E695K	0.07
SKCM	chr20	47210801	Missense_Mutation	NA	L1174R	0.15
SKCM	chr20	47246137	Missense_Mutation	NA	P699S	0.42
SKCM	chr20	47239093	Missense_Mutation	novel	P757L	0.28
SKCM	chr20	47239094	Missense_Mutation	novel	P757S	0.28
SKCM	chr20	47236339	Missense_Mutation	NA	K928M	0.16
SKCM	chr20	47239086	Missense_Mutation	NA	E759D	0.21
SKCM	chr20	47298839	Missense_Mutation	NA	H95Y	0.24
SKCM	chr20	47287285	Splice_Site	NA	X230_splice	0.27
SKCM	chr20	47224459	Silent	rs745982385	A1018A	0.08
SKCM	chr20	47298878	Missense_Mutation	NA	P82S	0.28
SKCM	chr20	47319110	Intron	novel		0.53
SKCM	chr20	47221398	Silent	rs778498926	S1091S	0.35
SKCM	chr20	47236465	Missense_Mutation	novel	L886Q	0.33
SKCM	chr20	47276460	Missense_Mutation	rs370213736	S425F	0.17
SKCM	chr20	47246296	Missense_Mutation	NA	E646K	0.23
SKCM	chr20	47224501	Silent	NA	I1004I	0.24
SKCM	chr20	47221432	Frame_Shift_Del	novel	*E1080Nfs4**	0.25
SKCM	chr20	47246466	Missense_Mutation	rs779100956	S589L	0.45
SKCM	chr20	47249437	Nonsense_Mutation	NA	R522*	0.21
SKCM	chr20	47294709	Missense_Mutation	NA	S155F	0.07
SKCM	chr20	47210732	3'UTR	novel		0.38
SKCM	chr20	47239124	Missense_Mutation	NA	P747S	0.48
SKCM	chr20	47221416	Silent	NA	S1085S	0.4
SKCM	chr20	47210625	3'UTR	novel		0.53
SKCM	chr20	47224390	Nonsense_Mutation	NA	W1041*	0.23
SKCM	chr20	47239124	Missense_Mutation	NA	P747S	0.1
SKCM	chr20	47262319	Silent	novel	S510S	0.44
SKCM	chr20	47298928	Missense_Mutation	NA	P65L	0.18
SKCM	chr20	47210645	3'UTR	novel		0.25
SKCM	chr20	47276462	Silent	novel	I424I	0.25
STAD	chr20	47282204	Missense_Mutation	novel	P279L	0.08
STAD	chr20	47246328	Frame_Shift_Del	NA	*K635Sfs14**	0.17
STAD	chr20	47246481	Missense_Mutation	NA	V584A	0.23
STAD	chr20	47318996	Intron	rs372958413		0.24
STAD	chr20	47224463	Missense_Mutation	NA	Q1017R	0.17
STAD	chr20	47224544	Missense_Mutation	NA	A990V	0.23
STAD	chr20	47239008	Silent	NA	V785V	0.08
STAD	chr20	47246492	Silent	NA	V580V	0.08
STAD	chr20	47236480	Missense_Mutation	rs373435522	T881M	0.32
STAD	chr20	47246062	Missense_Mutation	rs369749556	R724W	0.18
STAD	chr20	47246328	Frame_Shift_Del	NA	*K635Sfs14**	0.22
STAD	chr20	47283600	Missense_Mutation	NA	K265Q	0.4
STAD	chr20	47276577	Missense_Mutation	novel	A386V	0.05
STAD	chr20	47246328	Frame_Shift_Del	NA	*K635Sfs14**	0.19
STAD	chr20	47262286	Splice_Site	novel	X521_splice	0.33
STAD	chr20	47238984	Silent	rs765241161	A793A	0.39
STAD	chr20	47249409	Missense_Mutation	NA	E531V	0.42
STAD	chr20	47262358	Silent	rs769763992	Q497Q	0.2
STAD	chr20	47210711	3'UTR	rs375112962		0.04
STAD	chr20	47238951	Silent	rs768512649	P804P	0.22
STAD	chr20	47246328	Frame_Shift_Del	NA	*K635Sfs14**	0.42
STAD	chr20	47210760	3'UTR	novel		0.06
STAD	chr20	47221452	Silent	NA	A1073A	0.11
STAD	chr20	47246098	Missense_Mutation	rs772025610	E712K	0.32
STAD	chr20	47276352	Missense_Mutation	NA	A461V	0.13
STAD	chr20	47246046	Frame_Shift_Del	novel	*N729Ifs15**	0.11
STAD	chr20	47283581	Missense_Mutation	NA	C271Y	0.08
STAD	chr20	47291867	Missense_Mutation	NA	V177I	0.15
STAD	chr20	47224327	Nonsense_Mutation	NA	C1062*	0.25
STAD	chr20	47246328	Frame_Shift_Del	NA	*K635Sfs14**	0.12
STAD	chr20	47210710	3'UTR	rs370734592		0.12
STAD	chr20	47282126	Missense_Mutation	NA	A305V	0.06
STAD	chr20	47294721	Missense_Mutation	rs373916187	I151T	0.47
TGCT	chr20	47276318	Missense_Mutation	novel	S472R	0.27
TGCT	chr20	47246120	Silent	novel	G704G	0.17
THCA	chr20	47262385	Silent	rs773877846	S488S	0.06
UCEC	chr20	47246328	Frame_Shift_Del	NA	*K635Sfs14**	0.47
UCEC	chr20	47210397	3'UTR	novel		0.42
UCEC	chr20	47238986	Missense_Mutation	novel	A793T	0.14
UCEC	chr20	47356667	5'Flank	novel		0.36
UCEC	chr20	47249343	Missense_Mutation	NA	R553P	0.36
UCEC	chr20	47282122	Silent	NA	R306R	0.42
UCEC	chr20	47210813	Missense_Mutation	NA	S1170N	0.31
UCEC	chr20	47224428	Missense_Mutation	NA	A1029T	0.45
UCEC	chr20	47246328	Frame_Shift_Del	NA	*K635Sfs14**	0.2
UCEC	chr20	47262341	Missense_Mutation	rs143023321	T503M	0.08
UCEC	chr20	47276526	Missense_Mutation	novel	M403T	0.11
UCEC	chr20	47210618	3'UTR	rs561509419		0.37
UCEC	chr20	47283600	Missense_Mutation	NA	K265E	0.26
UCEC	chr20	47238658	Intron	novel		0.56
UCEC	chr20	47282114	Missense_Mutation	novel	G309V	0.38
UCEC	chr20	47290187	Missense_Mutation	rs112503437	G230R	0.41
UCEC	chr20	47238977	Nonsense_Mutation	novel	G796*	0.39
UCEC	chr20	47298860	Missense_Mutation	NA	D88Y	0.4
UCEC	chr20	47209826	3'UTR	rs188382531		0.48
UCEC	chr20	47236355	Missense_Mutation	novel	A923T	0.47
UCEC	chr20	47238912	Silent	rs779642631	V817V	0.44
UCEC	chr20	47310098	Missense_Mutation	novel	K44N	0.34
UCEC	chr20	47212667	Intron	rs768562222		0.04
UCEC	chr20	47282102	Missense_Mutation	NA	R313M	0.13
UCEC	chr20	47238339	Intron	novel		0.36
UCEC	chr20	47238986	Missense_Mutation	novel	A793T	0.33
UCEC	chr20	47246481	Missense_Mutation	NA	V584A	0.19
UCEC	chr20	47298765	Silent	novel	S119S	0.12
UCEC	chr20	47298732	Silent	NA	C130C	0.13
UCEC	chr20	47310131	Silent	rs550379713	S33S	0.43
UCEC	chr20	47291886	In_Frame_Ins	novel	T170_D171insLYIGK	0.08
UCEC	chr20	47276347	Missense_Mutation	novel	E463K	0.31
UCEC	chr20	47210151	3'UTR	rs6012135		0.4
UCEC	chr20	47210557	3'UTR	novel		0.46
UCEC	chr20	47221364	Missense_Mutation	rs143716806	A1103T	0.38
UCEC	chr20	47236438	Missense_Mutation	novel	L895Q	0.39
UCEC	chr20	47239024	Missense_Mutation	rs761740673	S780N	0.18
UCEC	chr20	47220295	Silent	rs768047560	T1129T	0.29
UCEC	chr20	47236391	Missense_Mutation	rs757483496	A911T	0.32
UCEC	chr20	47246327	Frame_Shift_Ins	rs776813452	*P636Afs10**	0.42
UCEC	chr20	47276686	Missense_Mutation	NA	V350M	0.41
UCEC	chr20	47246328	Frame_Shift_Del	NA	*K635Sfs14**	0.31
UCEC	chr20	47276673	Missense_Mutation	novel	R354H	0.46
UCEC	chr20	47246340	Missense_Mutation	NA	A631V	0.34
UCEC	chr20	47221471	Missense_Mutation	novel	T1067N	0.38
UCEC	chr20	47290275	Splice_Site	NA	X201_splice	0.26
UCEC	chr20	47310099	Frame_Shift_Del	novel	*K44Rfs8**	0.33
UCEC	chr20	47210810	Missense_Mutation	novel	T1171K	0.42
UCEC	chr20	47221396	Missense_Mutation	NA	S1092N	0.19
UCEC	chr20	47236324	Splice_Site	NA	X932_splice	0.32
UCEC	chr20	47249352	Missense_Mutation	NA	R550H	0.14
UCEC	chr20	47236391	Missense_Mutation	rs757483496	A911T	0.16
UCEC	chr20	47238424	Intron	novel		0.16
UCEC	chr20	47238703	Intron	novel		0.11
UCEC	chr20	47290269	Silent	rs141430390	A202A	0.22
UCEC	chr20	47246099	Silent	rs141781562	S711S	0.43
UCEC	chr20	47246280	Missense_Mutation	rs367967090	T651M	0.34
UCEC	chr20	47238863	Missense_Mutation	NA	M834V	0.5
UCEC	chr20	47238951	Silent	rs768512649	P804P	0.39
UCEC	chr20	47227221	Missense_Mutation	NA	E980K	0.39
UCEC	chr20	47348028	Intron	novel		0.46
UCEC	chr20	47209965	3'UTR	novel		0.34
UCEC	chr20	47238355	Intron	novel		0.28
UCEC	chr20	47249436	Missense_Mutation	novel	R522Q	0.47
UCEC	chr20	47319062	Intron	novel		0.7
UCEC	chr20	47239090	Missense_Mutation	rs780491504	P758L	0.28
UCEC	chr20	47246328	Frame_Shift_Del	NA	*K635Sfs14**	0.37
UCEC	chr20	47298928	Missense_Mutation	NA	P65L	0.08
UCEC	chr20	47246328	Frame_Shift_Del	NA	*K635Sfs14**	0.47
UCEC	chr20	47227221	Missense_Mutation	NA	E980K	0.24
UCEC	chr20	47210767	Nonsense_Mutation	novel	W1185*	0.24
UCEC	chr20	47224428	Missense_Mutation	NA	A1029T	0.28
UCEC	chr20	47298756	Missense_Mutation	novel	E122D	0.36
UCEC	chr20	47310059	Missense_Mutation	novel	E57D	0.12
UCEC	chr20	47356717	5'Flank	novel		0.05
UCEC	chr20	47238553	Intron	novel		0.44
UCEC	chr20	47246328	Frame_Shift_Del	NA	*K635Sfs14**	0.28
UCEC	chr20	47246486	Silent	rs535541680	T582T	0.48
UCEC	chr20	47238460	Intron	novel		0.31
UCEC	chr20	47210213	3'UTR	novel		0.35
UCEC	chr20	47220292	Silent	novel	P1130P	0.35
UCEC	chr20	47246413	Frame_Shift_Ins	novel	E607*	0.04
UCEC	chr20	47246415	Nonsense_Mutation	novel	*D606Afs7**	0.04
UCEC	chr20	47227283	Splice_Site	novel	X960_splice	0.36
UCEC	chr20	47224550	Missense_Mutation	novel	T988I	0.23
UCEC	chr20	47236500	Missense_Mutation	NA	E874D	0.13
UCEC	chr20	47262377	Missense_Mutation	NA	P491L	0.11
UCEC	chr20	47246171	Missense_Mutation	NA	K687N	0.04
UCEC	chr20	47224500	Missense_Mutation	rs367618268	A1005T	0.15
UCEC	chr20	47224501	Silent	NA	I1004I	0.16
UCEC	chr20	47229800	Missense_Mutation	novel	D935N	0.29
UCEC	chr20	47236428	Silent	novel	S898S	0.14
UCEC	chr20	47249402	Silent	rs373193167	S533S	0.13
UCEC	chr20	47290275	Splice_Site	novel	X201_splice	0.16
UCEC	chr20	47298829	Missense_Mutation	novel	G98V	0.11
UCEC	chr20	47347895	5'UTR	novel		0.21
UCEC	chr20	47246328	Frame_Shift_Del	NA	*K635Sfs14**	0.16
UCEC	chr20	47294767	Missense_Mutation	novel	A136T	0.29
UCEC	chr20	47318944	Intron	rs781166479		0.25
UCEC	chr20	47210887	Silent	NA	R1145R	0.1
UCEC	chr20	47246086	Missense_Mutation	NA	D716Y	0.29
UCEC	chr20	47246378	Missense_Mutation	NA	E618D	0.27
UCEC	chr20	47291867	Missense_Mutation	NA	V177I	0.3
UCEC	chr20	47249285	Splice_Site	NA	X572_splice	0.36
UCEC	chr20	47287268	Silent	rs139817127	T235T	0.36
UCEC	chr20	47298865	Missense_Mutation	novel	R86Q	0.29
UCEC	chr20	47221422	Silent	novel	N1083N	0.32
UCEC	chr20	47282131	Silent	novel	V303V	0.41
UCEC	chr20	47347912	5'UTR	novel		0.26
UCS	chr20	47224488	Missense_Mutation	novel	K1009E	0.34

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
LAML	DEL	0.0209	0.14746
LUAD	DEL	0.1085	0.18308
PRAD	AMP	0.0508	0.07085
UCEC	AMP	0.2301	2.4177e-07

Survival Analysis

Cancer	P-value	Q-value
THYM	0.022	Kaplan-Meier Survival Analysis
KIRC	0.00012	Kaplan-Meier Survival Analysis
MESO	0.028	Kaplan-Meier Survival Analysis
ACC	0.0098	Kaplan-Meier Survival Analysis
UCS	0.028	Kaplan-Meier Survival Analysis
BRCA	0.0099	Kaplan-Meier Survival Analysis
ESCA	0.008	Kaplan-Meier Survival Analysis
BLCA	0.0042	Kaplan-Meier Survival Analysis
LIHC	0.0007	Kaplan-Meier Survival Analysis
DLBC	0.023	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
UVM	0.0016	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000101040 (Gene tree)
Gene ID: 23613
Gene Symbol: ZMYND8
Alias: RACK7|PRKCBP1
Full Name: zinc finger MYND-type containing 8
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 147,676 bases
Position: chr20:47,209,214-47,356,889
Accession: 9397
RBP type: non-canonical RBP
Summary: The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000262975	ZMYND8-201	4139	XM_017027775	ENSP00000262975	1168 (aa)	XP_016883264	Q9ULU4
ENST00000352431	ZMYND8-203	3832	XM_017027760	ENSP00000335537	1160 (aa)	XP_016883249	Q9ULU4
ENST00000396281	ZMYND8-207	5511	XM_011528749	ENSP00000379577	1186 (aa)	XP_011527051	Q9ULU4
ENST00000441977	ZMYND8-209	175	-	ENSP00000393806	24 (aa)	-	Q5TH07
ENST00000540497	ZMYND8-218	3405	-	ENSP00000443086	1134 (aa)	-	Q9ULU4
ENST00000446894	ZMYND8-210	341	-	ENSP00000394379	42 (aa)	-	Q5TH08
ENST00000360911	ZMYND8-205	4991	XM_017027765	ENSP00000354166	1135 (aa)	XP_016883254	Q9ULU4
ENST00000435836	ZMYND8-208	670	-	ENSP00000413727	175 (aa)	-	Q5TH12
ENST00000355972	ZMYND8-204	5542	XM_011528753	ENSP00000348246	1214 (aa)	XP_011527055	Q9ULU4
ENST00000611941	ZMYND8-219	5090	XM_017027779	ENSP00000482048	1087 (aa)	XP_016883268	A0A087WYS3
ENST00000471951	ZMYND8-216	4053	XM_005260362	ENSP00000420095	1234 (aa)	XP_005260419	Q9ULU4
ENST00000311275	ZMYND8-202	5362	XM_005260366	ENSP00000312237	1186 (aa)	XP_005260423	Q9ULU4
ENST00000458360	ZMYND8-212	3729	XM_017027780	ENSP00000392964	1054 (aa)	XP_016883269	Q9ULU4
ENST00000372023	ZMYND8-206	5144	-	ENSP00000361093	1105 (aa)	-	Q9ULU4
ENST00000461685	ZMYND8-213	3567	-	ENSP00000418210	1188 (aa)	-	Q9ULU4
ENST00000468376	ZMYND8-215	4064	-	-	- (aa)	-	-
ENST00000536340	ZMYND8-217	5273	XM_005260356	ENSP00000439800	1241 (aa)	XP_005260413	Q9ULU4
ENST00000617418	ZMYND8-220	3411	-	ENSP00000479806	1136 (aa)	-	A0A087WVZ6
ENST00000467200	ZMYND8-214	3634	XM_017027774	ENSP00000418495	1095 (aa)	XP_016883263	H7C4X9
ENST00000619049	ZMYND8-221	4027	-	ENSP00000479197	767 (aa)	-	A0A087WV57
ENST00000446994	ZMYND8-211	5471	XM_005260358	ENSP00000396725	1214 (aa)	XP_005260415	Q9ULU4

Gene Model

Click here to download ENSG00000101040's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000101040	Asthma	9.434312E-06	11022011
ENSG00000101040	Coronary Disease	1.2510000E-005	-
ENSG00000101040	Platelet Function Tests	4.3000000E-007	-
ENSG00000101040	Platelet Function Tests	4.2900000E-006	-
ENSG00000101040	Platelet Function Tests	1.6007200E-005	-
ENSG00000101040	Platelet Function Tests	1.7432400E-005	-
ENSG00000101040	Child Development Disorders, Pervasive	4.0000000E-005	-
ENSG00000101040	Osteoarthritis	2E-10	23989986
ENSG00000101040	Migraine Disorders	4E-8	27182965

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000101040	rs17726337	20	47315915	C	Mean platelet volume	27863252	[0.069-0.107] unit decrease	0.08812654	EFO_0004584
ENSG00000101040	rs6063085	20	47211814	A	Depressive symptoms (MTAG)	29292387	[0.0085-0.0171] unit increase	0.0128	EFO_0007006
ENSG00000101040	rs6063085	20	47211814	A	Subjective well-being (MTAG)	29292387	[0.0088-0.0162] unit decrease	0.0125	EFO_0007869
ENSG00000101040	rs910187	20	47212407	?	Migraine	27182965	[1.029-1.061]	1.045	EFO_0003821
ENSG00000101040	rs57808107	20	47232164	?	Plasma factor VII activating protease levels	30070759	[60.14-142.86] unit increase	101.5	EFO_0009368
ENSG00000101040	rs910187	20	47212407	A	Neuroticism	30643256	[0.0067-0.0128] unit decrease	0.009757282	EFO_0007660
ENSG00000101040	rs910187	20	47212407	A	Depressive symptoms	30643256	[0.0043-0.0082] unit decrease	0.006215197	EFO_0007006
ENSG00000101040	rs910187	20	47212407	?	Neuroticism	30595370			EFO_0007660
ENSG00000101040	rs910187	20	47212407	A	Well-being spectrum (multivariate analysis)	30643256	[0.0045-0.0082] unit decrease	0.006336388	EFO_0007869

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000101040's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000101040	ZMYND8	100	96.000	ENSMUSG00000039671	Zmynd8	99	92.569	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003714	transcription corepressor activity	27477906.	IMP	Function
GO:0003714	transcription corepressor activity	-	ISS	Function
GO:0005515	protein binding	15095401.16147992.28966017.	IPI	Function
GO:0005634	nucleus	27477906.28966017.	IDA	Component
GO:0005634	nucleus	-	ISS	Component
GO:0005737	cytoplasm	28966017.	IMP	Component
GO:0006355	regulation of transcription, DNA-templated	-	IEA	Process
GO:0008270	zinc ion binding	28966017.	IDA	Function
GO:0019904	protein domain specific binding	28966017.	IDA	Function
GO:0030336	negative regulation of cell migration	27477906.	IMP	Process
GO:0035064	methylated histone binding	27477906.	IDA	Function
GO:0043197	dendritic spine	-	IEA	Component
GO:0043198	dendritic shaft	-	IEA	Component
GO:0047485	protein N-terminus binding	-	IEA	Function
GO:0051491	positive regulation of filopodium assembly	-	IEA	Process
GO:0060999	positive regulation of dendritic spine development	-	IEA	Process
GO:0070491	repressing transcription factor binding	-	ISS	Function
GO:0070577	lysine-acetylated histone binding	27477906.	IDA	Function
GO:0098815	modulation of excitatory postsynaptic potential	-	IEA	Process
GO:1902897	regulation of postsynaptic density protein 95 clustering	-	IEA	Process
GO:1902952	positive regulation of dendritic spine maintenance	-	IEA	Process
GO:1903507	negative regulation of nucleic acid-templated transcription	-	IEA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.