EuRBPDB

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TCGA tumor abbreviations
  • ACCAdrenocortical carcinoma
  • BLCABladder Urothelial Carcinoma
  • BRCABreast invasive carcinoma
  • CESCCervical squamous cell carcinoma and endocervical adenocarcinoma
  • CHOLCholangio carcinoma
  • COADColon adenocarcinoma
  • DLBCLymphoid Neoplasm Diffuse Large B-cell Lymphoma
  • ESCAEsophageal carcinoma
  • GBMGlioblastoma multiforme
  • HNSCHead and Neck squamous cell carcinoma
  • KICHKidney Chromophobe
  • KIRCKidney renal clear cell carcinoma
  • KIRPKidney renal papillary cell carcinoma
  • LAMLAcute Myeloid Leukemia
  • LGGBrain Lower Grade Glioma
  • LIHCLiver hepatocellular carcinoma
  • LUADLung adenocarcinoma
  • LUSCLung squamous cell carcinoma
  • MESOMesothelioma
  • OVOvarian serous cystadenocarcinoma
  • PAADPancreatic adenocarcinoma
  • PCPGPheochromocytoma and Paraganglioma
  • PRADProstate adenocarcinoma
  • READRectum adenocarcinoma
  • SARCSarcoma
  • SKCMSkin Cutaneous Melanoma
  • STADStomach adenocarcinoma
  • TGCTThyroid carcinoma
  • THCAThyroid carcinoma
  • THYMThymoma
  • UCECUterine Corpus Endometrial Carcinoma
  • UCSUterine Carcinosarcoma
  • UVMUveal Melanoma

Note: Click here to get the extension of tumor abbreviations.


  • Cancer Related Information
  • Basic Information

Cancer associated literatures
PIDTitleArticle TimeAuthorDoi
27315569Protein arginine methyltransferase 5 is associated with malignant phenotype and peritoneal metastasis in gastric cancer.Int J Oncol2016 SepKanda Mdoi: 10.3892/ijo.2016.3584
29802960Protein arginine methyltransferase 5-mediated epigenetic silencing of IRX1 contributes to tumorigenicity and metastasis of gastric cancer.Biochim Biophys Acta Mol Basis Dis2018 SepLiu Xdoi: 10.1016/j.bbadis.2018.05.015
22266372Protein arginine methyltransferase 5 is an essential component of the hypoxia-inducible factor 1 signaling pathway.Biochem Biophys Res Commun2012 Feb 10Lim JHdoi: 10.1016/j.bbrc.2012.01.006
28854561Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation.Carcinogenesis2017 Aug 1Saha Kdoi: 10.1093/carcin/bgx044.
18694959Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cells.Mol Cell Biol2008 OctWang Ldoi: 10.1128/MCB.00923-08
21700716Protein arginine methyltransferase 5 accelerates tumor growth by arginine methylation of the tumor suppressor programmed cell death 4.Cancer Res2011 Aug 15Powers MAdoi: 10.1158/0008-5472.CAN-11-0458
25220593Late Cornified Envelope Group I, a novel target of p53, regulates PRMT5 activity.Neoplasia2014 AugDeng Zdoi: 10.1016/j.neo.2014.07.008.
24453002Genetic validation of the protein arginine methyltransferase PRMT5 as a candidate therapeutic target in glioblastoma.Cancer Res2014 Mar 15Yan Fdoi: 10.1158/0008-5472.CAN-13-0884
24664369Expression of PRMT5 correlates with malignant grade in gliomas and plays a pivotal role in tumor growth in vitro.J Neurooncol2014 MayHan Xdoi: 10.1007/s11060-014-1419-0
29185119PRMT5 determines the sensitivity to chemotherapeutics by governing stemness in breast cancer.Breast Cancer Res Treat2018 AprWang Zdoi: 10.1007/s10549-017-4597-6
22708516Protein arginine methyltransferase 5 is essential for growth of lung cancer cells.Biochem J2012 Sep 1Gu Zdoi: 10.1042/BJ20120768.
25281873Transcriptional activation of PRMT5 by NF-Y is required for cell growth and negatively regulated by the PKC/c-Fos signaling in prostate cancer cells.Biochim Biophys Acta2014 NovZhang HTdoi: 10.1016/j.bbagrm.2014.09.015
23292799Overexpression of PRMT5 promotes tumor cell growth and is associated with poor disease prognosis in epithelial ovarian cancer.J Histochem Cytochem2013 MarBao Xdoi: 10.1369/0022155413475452
26912360MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells.Science2016 Mar 11Kryukov GVdoi: 10.1126/science.aad5214
17627275Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma.EMBO J2007 Aug 8Pal S-
25704480Proliferative role of TRAF4 in breast cancer by upregulating PRMT5 nuclear expression.Tumour Biol2015 AugYang Fdoi: 10.1007/s13277-015-3262-0
15701830Identification of gastric cancer-related genes using a cDNA microarray containing novel expressed sequence tags expressed in gastric cancer cells.Clin Cancer Res2005 Jan 15Kim JM-
28381188Elevated expression of protein arginine methyltransferase 5 predicts the poor prognosis of breast cancer.Tumour Biol2017 AprWu Ydoi: 10.1177/1010428317695917.
27546619Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth.Oncogene2017 Mar 2Deng Xdoi: 10.1038/onc.2016.287
27183006ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor.Elife2016 May 16Mounir Zdoi: 10.7554/eLife.13964.
28987382Arginine methyltransferase inhibitor 1 inhibits gastric cancer by downregulating eIF4E and targeting PRMT5.Toxicol Appl Pharmacol2017 Dec 1Zhang Bdoi: 10.1016/j.taap.2017.10.002
26990556Anguilla japonica lectin 1 delivery through adenovirus vector induces apoptotic cancer cell death through interaction with PRMT5.J Gene Med2016 AprLi Gdoi: 10.1002/jgm.2878.
28591716Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers.Oncotarget2017 Jun 20Prabhu Ldoi: 10.18632/oncotarget.18102.
29262329PRMT5 Is a Critical Regulator of Breast Cancer Stem Cell Function via Histone Methylation and FOXP1 Expression.Cell Rep2017 Dec 19Chiang Kdoi: 10.1016/j.celrep.2017.11.096.
29749478Protein arginine methyltransferase 5 is implicated in the aggressiveness of human hepatocellular carcinoma and controls the invasive activity of cancer cells.Oncol Rep2018 JulJeon JYdoi: 10.3892/or.2018.6402

Expression in 33 cancers

Mutations
CancerChrPosition Mutation TypedbSNPProtein-change Allele FreqRBD
BLCAchr1422922206SilentnovelF577F0.28
BLCAchr1422926264Missense_MutationNAH216Y0.44
BLCAchr1422929289Missense_MutationNAE25K0.49
BLCAchr1422924653Missense_MutationNAI332M0.09
BLCAchr1422928583Missense_MutationNAP48Q0.23
BRCAchr1422924705Missense_MutationNAL315P0.34
BRCAchr1422922557Missense_MutationNAP528S0.14
BRCAchr1422929331Missense_MutationNAG11W0.43
BRCAchr14229207863'UTRnovel0.18
BRCAchr1422926264Missense_MutationNAH216Y0.2
BRCAchr1422928611Missense_MutationNAD39H0.28
BRCAchr1422924917In_Frame_DelnovelE298_F300del0.31
BRCAchr1422929216IntronNA0.18
CESCchr1422929323Silentrs765654523R13R0.11
CESCchr14229207333'UTRnovel0.24
CESCchr1422925026SilentNAF264F0.08
CESCchr1422926251Missense_Mutationrs768729897R220H0.37
CESCchr1422926805Missense_Mutationrs373936905R154W0.45
CESCchr1422926257Missense_MutationnovelI218S0.23
CESCchr1422923103Missense_MutationNAS478F0.49
COADchr1422924921SilentNAL299L0.38
COADchr14229208813'UTRnovel0.18
COADchr1422922242Splice_SiteNAX566_splice0.18
COADchr1422923140Missense_MutationnovelG466R0.33
COADchr1422929217IntronNA0.35
COADchr1422924962Missense_MutationNAY286H0.38
COADchr1422929361Translation_Start_SiteNAM1?0.3
COADchr1422922539Missense_MutationNAR534C0.22
COADchr1422928150Missense_MutationnovelE97D0.59
ESCAchr1422924938Missense_MutationnovelP294S0.21
ESCAchr14229207993'UTRnovel0.3
GBMchr1422924354Missense_MutationnovelV372G0.08
GBMchr1422920976SilentnovelE614E0.55
HNSCchr1422924501Missense_MutationnovelE352Q0.11
HNSCchr1422926174Missense_MutationNAL246F0.28
HNSCchr14229293655'UTRnovel0.32
KIRCchr1422924160Missense_MutationNAE408V0.26
KIRPchr1422924147In_Frame_InsnovelF406_Q412dup0.1
KIRPchr1422924482Missense_MutationnovelV358D0.21
KIRPchr1422928193Missense_MutationNAV83A0.41
LGGchr1422920957Missense_MutationNAV621I0.37
LGGchr1422926266Missense_MutationNAN215S0.09
LGGchr1422924325Missense_MutationnovelA382T0.25
LGGchr1422920991SilentnovelK609K0.35
LIHCchr1422929275SilentnovelT29T0.44
LUADchr1422929223Intronrs3769815250.16
LUADchr1422928581Missense_MutationNAR49C0.3
LUADchr1422929347SilentNAA5A0.43
LUADchr1422923093Nonsense_MutationNAY481*0.33
LUADchr1422924337Missense_MutationNAA378P0.33
LUADchr1422926556Splice_SitenovelX188_splice0.16
LUADchr1422928536Missense_MutationNAG64C0.35
LUADchr1422920976Missense_MutationNAE614D0.23
LUSCchr1422922485Missense_MutationnovelA552T0.17
LUSCchr1422929241Intronnovel0.15
LUSCchr1422920990Nonsense_MutationnovelK610*0.44
LUSCchr1422921040Missense_MutationNAR593L0.19
LUSCchr1422926812Splice_RegionnovelF151F0.15
LUSCchr1422924643Nonsense_MutationNAQ336*0.09
OVchr1422924032Missense_Mutationrs756575000D451H0.04
OVchr1422926251Missense_Mutationrs768729897R220H0.33
OVchr1422924925Missense_MutationnovelE298G0.06
OVchr1422928568Missense_MutationnovelE53G0.03
PAADchr1422929194Intronnovel0.16
PRADchr1422929183IntronNA0.31
PRADchr1422926806Missense_MutationnovelM153I0.52
SARCchr14229206103'UTRrs7683049490.16
SARCchr1422924182Missense_MutationnovelL401I0.09
SKCMchr1422924481Splice_RegionnovelV358V0.32
SKCMchr14229293885'UTRrs5348251290.77
SKCMchr1422924345Missense_MutationNAS375F0.19
SKCMchr1422927533Missense_MutationNAS148F0.29
SKCMchr1422928143Missense_MutationNAR100C0.06
SKCMchr1422929349Missense_MutationNAA5T0.48
SKCMchr14229208433'UTRnovel0.35
SKCMchr1422926276Missense_MutationnovelL212F0.38
SKCMchr1422926277SilentnovelD211D0.38
SKCMchr1422926180Missense_MutationNAP244S0.19
SKCMchr1422924345Missense_MutationNAS375F0.34
SKCMchr14229208653'UTRnovel0.16
SKCMchr1422924345Missense_MutationNAS375F0.45
SKCMchr1422923126SilentNAS470S0.19
SKCMchr1422923127Missense_MutationNAS470F0.65
SKCMchr1422923127Missense_MutationNAS470F0.33
SKCMchr1422927615Missense_MutationnovelA121T0.2
SKCMchr1422924018SilentNAH455H0.18
SKCMchr1422928611Missense_MutationnovelD39N0.11
STADchr1422922510Missense_MutationnovelE543D0.15
STADchr1422922831Missense_MutationNAQ497R0.42
STADchr1422928524Nonsense_Mutationrs374788457R68*0.07
STADchr1422924174SilentNAN403N0.18
THYMchr1422926710Silentrs759956527T185T0.29
UCECchr14229207433'UTRnovel0.32
UCECchr1422929269SilentnovelG31G0.09
UCECchr1422928181Missense_MutationNAS87Y0.35
UCECchr14229208503'UTRnovel0.37
UCECchr1422924977Missense_MutationnovelL281I0.1
UCECchr1422924269Splice_SiteNAX400_splice0.51
UCECchr1422924634Nonsense_MutationnovelQ339*0.42
UCECchr1422927573Missense_MutationnovelA135T0.05
UCECchr1422923129SilentNAT469T0.04
UCECchr1422922242Splice_SiteNAX566_splice0.57
UCECchr14229208973'UTRrs7524046480.1
UCECchr1422929191Intronnovel0.09
UCECchr1422928169Missense_Mutationrs757013591R91H0.24
UCECchr14229206483'UTRnovel0.54
UCECchr1422928564Missense_MutationnovelF54L0.31
UCECchr1422924325Missense_MutationnovelA382T0.28
UCECchr1422924045Silentrs749432721S446S0.32
UCECchr1422926701Splice_SitenovelX188_splice0.31
UCECchr1422926176Missense_MutationNAV245A0.21
UCECchr1422924373Missense_MutationNAA366T0.11
UCECchr1422926780Missense_MutationnovelD162G0.31
UCECchr1422922750Missense_MutationnovelP524L0.52
UCECchr1422929222Intronrs7588527440.38
UCECchr1422922538Missense_Mutationrs754873481R534H0.35
UCECchr14229206263'UTRnovel0.23
UCECchr1422928202Missense_MutationNAT80M0.39
UCECchr1422924179Missense_MutationNAE402Q0.42
UCECchr14229207083'UTRnovel0.5
UCECchr1422924154Missense_MutationnovelG410E0.49
UCECchr1422928164Missense_MutationnovelD93N0.3
UCECchr1422924318Missense_MutationnovelR384Q0.17
UCECchr14229208433'UTRnovel0.47
UCECchr1422928179Missense_MutationnovelP88T0.21
UCECchr1422920909Missense_MutationNAL637I0.13
UCECchr1422926297Splice_SiteNAX205_splice0.31

Copy Number Variations (CNVs)
CancerTypeFreq Q-value
ACCAMP0.26670.056464
ACCDEL0.15560.19769
CHOLDEL0.36110.00040262
HNSCDEL0.12070.0025503
KIRPDEL0.16670.085174
LUSCDEL0.26150.0082553
PAADDEL0.07610.11332

Survival Analysis
CancerP-value Q-value
KIRC0.00011

Kaplan-Meier Survival Analysis

SARC0.013

Kaplan-Meier Survival Analysis

ACC0.00045

Kaplan-Meier Survival Analysis

HNSC0.00028

Kaplan-Meier Survival Analysis

PAAD0.0002

Kaplan-Meier Survival Analysis

PCPG0.036

Kaplan-Meier Survival Analysis

BLCA0.00072

Kaplan-Meier Survival Analysis

CESC0.013

Kaplan-Meier Survival Analysis

GBM0.0049

Kaplan-Meier Survival Analysis

LIHC0.00064

Kaplan-Meier Survival Analysis

LGG0.00011

Kaplan-Meier Survival Analysis

LUAD0.025

Kaplan-Meier Survival Analysis

UVM0.016

Kaplan-Meier Survival Analysis

Drugs

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Eesembl ID



Cell lines and drugs in GSE70138 or GSE92742

  • Description
  • RBPome
  • Literatures
  • Expression
  • Transcripts
  • Gene Model
  • Pathways
  • PPI
  • Gene Ontology
Description
Ensembl ID
ENSG00000100462 (Gene tree)
Gene ID
10419
Gene Symbol
PRMT5
Alias
SKB1Hs|HRMT1L5|SKB1
Full Name
protein arginine methyltransferase 5
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Minus strand
Length
9,075 bases
Position
chr14:22,920,511-22,929,585
Accession
10894
RBP type
non-canonical RBP
Summary
This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
29431736Capturing the interactome of newly transcribed RNAPolyT-RICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595

Literatures on RNA binding capacity
PIDTitleArticle TimeAuthorDoi
27577262Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells.Sci Signal2016 Aug 30Larsen SCdoi: 10.1126/scisignal.aaf7329.
21081503RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.J Biol Chem2011 Jan 21Guderian Gdoi: 10.1074/jbc.M110.148486
28972166Histone arginine demethylase JMJD6 is linked to stress granule assembly through demethylation of the stress granule-nucleating protein G3BP1.J Biol Chem2017 Nov 17Tsai WCdoi: 10.1074/jbc.M117.800706
19520849Role of pICLn in methylation of Sm proteins by PRMT5.J Biol Chem2009 Aug 7Pesiridis GSdoi: 10.1074/jbc.M109.015578
19234465PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.Nat Struct Mol Biol2009 MarZhao Qdoi: 10.1038/nsmb.1568
28236308PRMT5 restricts hepatitis B virus replication through epigenetic repression of covalently closed circular DNA transcription and interference with pregenomic RNA encapsidation.Hepatology2017 AugZhang Wdoi: 10.1002/hep.29133
29920217Induction of DUSP14 ubiquitination by PRMT5-mediated arginine methylation.FASEB J2018 Jun 19:fj201800244RRYang CYdoi: 10.1096/fj.201800244RR
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000476175PRMT5-207682--- (aa)--
ENST00000557758PRMT5-227597--- (aa)--
ENST00000554716PRMT5-215561--- (aa)--
ENST00000553915PRMT5-2141931-ENSP0000045112769 (aa)-G3V3A3
ENST00000556032PRMT5-220643--- (aa)--
ENST00000554910PRMT5-217577-ENSP00000452411169 (aa)-G3V5L5
ENST00000557443PRMT5-226337-ENSP0000045250161 (aa)-H0YJY6
ENST00000556426PRMT5-222563--- (aa)--
ENST00000553550PRMT5-210580-ENSP00000450737183 (aa)-G3V2L6
ENST00000553641PRMT5-211800--- (aa)--
ENST00000553417PRMT5-208259--- (aa)--
ENST00000553787PRMT5-212579-ENSP0000045210242 (aa)-G3V507
ENST00000397440PRMT5-2031907-ENSP00000380582466 (aa)-O14744
ENST00000397441PRMT5-2042418-ENSP00000380583620 (aa)-O14744
ENST00000557015PRMT5-224628--- (aa)--
ENST00000553897PRMT5-2131857-ENSP00000452555593 (aa)-O14744
ENST00000421938PRMT5-205565-ENSP00000409482186 (aa)-C9JSX3
ENST00000556616PRMT5-223571-ENSP00000450919185 (aa)-G3V2X6
ENST00000627278PRMT5-228129-ENSP0000048578742 (aa)-G3V507
ENST00000554867PRMT5-216555-ENSP00000452218180 (aa)-G3V580
ENST00000216350PRMT5-2012271-ENSP00000216350576 (aa)-O14744
ENST00000555454PRMT5-218771-ENSP00000451245177 (aa)-H0YJD3
ENST00000557415PRMT5-225584-ENSP0000045063386 (aa)-G3V2F5
ENST00000324366PRMT5-2022531-ENSP00000319169637 (aa)-O14744
ENST00000556043PRMT5-221603-ENSP00000452509104 (aa)-G3V5T6
ENST00000454731PRMT5-206617-ENSP00000387663179 (aa)-H7BZ44
ENST00000555530PRMT5-219837-ENSP00000452409279 (aa)-H0YJX6
ENST00000553502PRMT5-209414-ENSP00000450956138 (aa)-H0YJ77
Gene Model
Click here to download ENSG00000100462's gene model file
Pathways
Pathway IDPathway NameSource
hsa03013RNA transportKEGG
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000100462's network

* RBP PPI network refers to all genes directly bind to RBP
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0000387spliceosomal snRNP assembly17709427.IMPProcess
GO:0000387spliceosomal snRNP assembly-TASProcess
GO:0003714transcription corepressor activity-ISSFunction
GO:0005515protein binding11756452.16087681.18404153.18984161.19234465.20133701.20159986.20421892.20810653.20951943.21081503.22269951.22327218.22365833.23071334.23455924.23892143.25092918.25284789.25852190.26700805.26763441.26912361.IPIFunction
GO:0005634nucleus21873635.IBAComponent
GO:0005634nucleus21081503.IDAComponent
GO:0005634nucleus18404153.NASComponent
GO:0005654nucleoplasm-TASComponent
GO:0005737cytoplasm22952863.IDAComponent
GO:0005794Golgi apparatus20421892.IDAComponent
GO:0005829cytosol21873635.IBAComponent
GO:0005829cytosol18984161.21081503.IDAComponent
GO:0005829cytosol-TASComponent
GO:0006353DNA-templated transcription, termination26700805.IMPProcess
GO:0007088regulation of mitotic nuclear division9843966.TASProcess
GO:0008168methyltransferase activity15369763.IDAFunction
GO:0008283cell proliferation9843966.TASProcess
GO:0008327methyl-CpG binding25284789.IDAFunction
GO:0008469histone-arginine N-methyltransferase activity21873635.IBAFunction
GO:0008469histone-arginine N-methyltransferase activity-TASFunction
GO:0016274protein-arginine N-methyltransferase activity20421892.26554819.IDAFunction
GO:0018216peptidyl-arginine methylation17709427.IMPProcess
GO:0019918peptidyl-arginine methylation, to symmetrical-dimethyl arginine-IEAProcess
GO:0032922circadian regulation of gene expression-ISSProcess
GO:0034709methylosome18984161.25284789.IDAComponent
GO:0034969histone arginine methylation21873635.IBAProcess
GO:0035097histone methyltransferase complex23048031.IDAComponent
GO:0035243protein-arginine omega-N symmetric methyltransferase activity19011621.EXPFunction
GO:0035243protein-arginine omega-N symmetric methyltransferase activity17709427.IMPFunction
GO:0035246peptidyl-arginine N-methylation15369763.26554819.IDAProcess
GO:0042118endothelial cell activation22269951.IMPProcess
GO:0042802identical protein binding11756452.22365833.23071334.IPIFunction
GO:0043021ribonucleoprotein complex binding17709427.IPIFunction
GO:0043985histone H4-R3 methylation-ISSProcess
GO:0043985histone H4-R3 methylation18404153.NASProcess
GO:0044020histone methyltransferase activity (H4-R3 specific)25284789.IMPFunction
GO:0044030regulation of DNA methylation-IEAProcess
GO:0045596negative regulation of cell differentiation-IEAProcess
GO:0046982protein heterodimerization activity18495660.IDAFunction
GO:0048714positive regulation of oligodendrocyte differentiation-IEAProcess
GO:0070372regulation of ERK1 and ERK2 cascade-IEAProcess
GO:0070888E-box binding-ISSFunction
GO:0090161Golgi ribbon formation20421892.IMPProcess
GO:0097421liver regeneration-IEAProcess
GO:1901796regulation of signal transduction by p53 class mediator-TASProcess
GO:1903507negative regulation of nucleic acid-templated transcription-IEAProcess
GO:1904992positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway26554819.IGIProcess
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