EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
19764998	Down-regulation of pescadillo inhibits proliferation and tumorigenicity of breast cancer cells.	Cancer Sci	2009 Dec	Li J	doi: 10.1111/j.1349-7006.2009.01325.x
23333390	PES1 regulates sensitivity of colorectal cancer cells to anticancer drugs.	Biochem Biophys Res Commun	2013 Feb 15	Xie W	doi: 10.1016/j.bbrc.2012.12.145
22820289	PES1 promotes breast cancer by differentially regulating ERα and ERβ.	J Clin Invest	2012 Aug	Cheng L	doi: 10.1172/JCI62676
26423399	Repression of PES1 expression inhibits growth of gastric cancer.	Tumour Biol	2016 Mar	Li J	doi: 10.1007/s13277-015-4069-8
24376209	PES1 differentially regulates the expression of ERα and ERβ in ovarian cancer.	IUBMB Life	2013 Dec	Li J	doi: 10.1002/iub.1228

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr22	30584660	Missense_Mutation	NA	F142L	0.12
BRCA	chr22	30579205	Missense_Mutation	NA	E485K	0.18
BRCA	chr22	30579895	Missense_Mutation	rs147644381	A404T	0.33
BRCA	chr22	30589245	Missense_Mutation	NA	Y17C	0.34	Pescadillo_N
CESC	chr22	30579762	Missense_Mutation	NA	G448E	0.1
CESC	chr22	30576849	3'UTR	novel		0.67
CESC	chr22	30581602	Missense_Mutation	rs781772847	E225K	0.45
CESC	chr22	30580100	Silent	novel	T374T	0.5
CESC	chr22	30579195	Missense_Mutation	NA	S488L	0.19
COAD	chr22	30580170	Missense_Mutation	NA	G351D	0.31
COAD	chr22	30580653	Nonsense_Mutation	novel	E321*	0.29
COAD	chr22	30580068	Missense_Mutation	novel	T385I	0.21
COAD	chr22	30584709	Missense_Mutation	NA	T126M	0.29	Pescadillo_N
COAD	chr22	30581531	Silent	rs147244950	P248P	0.4
COAD	chr22	30578920	Missense_Mutation	novel	R534S	0.21
COAD	chr22	30577096	Missense_Mutation	rs750124332	D573N	0.13
COAD	chr22	30587333	Missense_Mutation	NA	L107F	0.17	Pescadillo_N
COAD	chr22	30581055	Missense_Mutation	novel	A290V	0.23
COAD	chr22	30581533	Missense_Mutation	NA	P248T	0.16
ESCA	chr22	30579895	Missense_Mutation	novel	A404S	0.42
GBM	chr22	30584631	Missense_Mutation	rs780076199	K152R	0.31
HNSC	chr22	30587360	Missense_Mutation	novel	K98N	0.19	Pescadillo_N
HNSC	chr22	30579220	Missense_Mutation	novel	E480K	0.23
HNSC	chr22	30580087	Missense_Mutation	NA	D379N	0.17
HNSC	chr22	30584454	Missense_Mutation	novel	V181I	0.16
HNSC	chr22	30581588	Silent	rs778185797	T229T	0.12
HNSC	chr22	30579203	Missense_Mutation	novel	E485D	0.33
HNSC	chr22	30589263	Missense_Mutation	rs529713663	R11Q	0.08	Pescadillo_N
KIRC	chr22	30577108	Missense_Mutation	NA	R569W	0.31
KIRC	chr22	30584415	Missense_Mutation	rs748306040	V194I	0.21
LAML	chr22	30581608	Missense_Mutation	novel	F223L	0.67
LIHC	chr22	30589193	Missense_Mutation	novel	F34L	0.5	Pescadillo_N
LIHC	chr22	30581614	Missense_Mutation	novel	A221P	0.21
LUAD	chr22	30578944	Nonsense_Mutation	NA	Q526*	0.09
LUAD	chr22	30581623	Missense_Mutation	novel	R218W	0.38
LUAD	chr22	30581545	Missense_Mutation	NA	L244F	0.53
LUAD	chr22	30588119	Missense_Mutation	novel	V54F	0.14	Pescadillo_N
LUAD	chr22	30578989	Missense_Mutation	novel	V511L	0.42
LUAD	chr22	30580176	Missense_Mutation	novel	S349T	0.08
LUSC	chr22	30581580	Missense_Mutation	novel	G232V	0.18
LUSC	chr22	30588171	Silent	novel	R36R	0.14
LUSC	chr22	30579761	Silent	NA	G448G	0.34
LUSC	chr22	30581017	Missense_Mutation	novel	D303H	0.29
LUSC	chr22	30579762	Missense_Mutation	NA	G448E	0.23
LUSC	chr22	30579763	Missense_Mutation	NA	G448R	0.23
LUSC	chr22	30584550	Missense_Mutation	rs746766101	R179H	0.6
LUSC	chr22	30587353	In_Frame_Ins	novel	S99_E100dup	0.13	Pescadillo_N
OV	chr22	30581028	Missense_Mutation	novel	E299A	0.46
PAAD	chr22	30579156	Missense_Mutation	novel	E501G	0.32
PAAD	chr22	30584624	Silent	rs769557165	H154H	0.17
PAAD	chr22	30580096	Missense_Mutation	novel	Q376K	0.2
PAAD	chr22	30587337	Missense_Mutation	rs750067678	R106H	0.14	Pescadillo_N
PRAD	chr22	30580087	Missense_Mutation	NA	D379N	0.3
PRAD	chr22	30581359	Missense_Mutation	rs537835882	A266V	0.33
SARC	chr22	30584643	Missense_Mutation	rs545460660	P148L	0.16
SARC	chr22	30592187	5'Flank	NA		0.13
SARC	chr22	30592188	5'Flank	novel		0.11
SKCM	chr22	30578957	Silent	NA	K521K	0.31
SKCM	chr22	30589193	Splice_Region	NA	F34F	0.16
SKCM	chr22	30581405	Missense_Mutation	rs145353108	E251K	0.4
SKCM	chr22	30576939	3'UTR	novel		0.5
SKCM	chr22	30579774	Missense_Mutation	novel	A444V	0.3
SKCM	chr22	30579881	Silent	rs766966200	L408L	0.16
SKCM	chr22	30578843	Silent	NA	I559I	0.4
SKCM	chr22	30588062	Missense_Mutation	NA	L73F	0.42	Pescadillo_N
SKCM	chr22	30580597	Silent	rs768059240	P339P	0.23
SKCM	chr22	30584660	Silent	NA	F142F	0.45
SKCM	chr22	30588128	Missense_Mutation	NA	K51E	0.43	Pescadillo_N
STAD	chr22	30584643	Missense_Mutation	rs545460660	P148L	0.53
STAD	chr22	30581565	Missense_Mutation	rs376966812	R237H	0.26
STAD	chr22	30581409	Splice_Site	NA	X250_splice	0.14
STAD	chr22	30580120	Missense_Mutation	rs149717169	V368I	0.39
STAD	chr22	30584680	Missense_Mutation	NA	D136N	0.17	Pescadillo_N
STAD	chr22	30581589	Missense_Mutation	rs142214789	T229M	0.41
STAD	chr22	30588037	Missense_Mutation	NA	K81T	0.08	Pescadillo_N
STAD	chr22	30579235	Missense_Mutation	NA	G475R	0.45
THYM	chr22	30576961	3'UTR	novel		0.1
UCEC	chr22	30579281	Silent	NA	E459E	0.4
UCEC	chr22	30579895	Missense_Mutation	rs147644381	A404T	0.2
UCEC	chr22	30577096	Missense_Mutation	rs750124332	D573N	0.31
UCEC	chr22	30581599	Missense_Mutation	novel	F226L	0.3
UCEC	chr22	30584701	Missense_Mutation	rs376323018	D129N	0.64	Pescadillo_N
UCEC	chr22	30580127	Silent	novel	T365T	0.46
UCEC	chr22	30591819	Missense_Mutation	NA	E5D	0.25	Pescadillo_N
UCEC	chr22	30592217	5'Flank	novel		0.42
UCEC	chr22	30580641	Missense_Mutation	NA	K325Q	0.44
UCEC	chr22	30584709	Missense_Mutation	NA	T126M	0.38	Pescadillo_N
UCEC	chr22	30580124	Silent	NA	Y366Y	0.23
UCEC	chr22	30578889	Missense_Mutation	novel	E544G	0.34
UCEC	chr22	30577068	Missense_Mutation	novel	A582V	0.37
UCEC	chr22	30579821	Silent	rs147465498	T428T	0.4
UCEC	chr22	30587312	Silent	rs751028632	Y114Y	0.38
UCEC	chr22	30580108	Missense_Mutation	rs763142101	R372C	0.3
UCEC	chr22	30581017	Missense_Mutation	rs773019625	D303N	0.55
UCEC	chr22	30578834	Splice_Region	novel		0.39
UCEC	chr22	30592372	5'Flank	novel		0.25
UCEC	chr22	30580083	Missense_Mutation	rs202135025	R380Q	0.33
UCEC	chr22	30581634	Missense_Mutation	novel	D214G	0.17
UCEC	chr22	30581039	Silent	rs751574321	A295A	0.29
UCEC	chr22	30579205	Missense_Mutation	NA	E485K	0.63
UCEC	chr22	30592329	5'Flank	novel		0.16
UCEC	chr22	30577121	Silent	novel	K564K	0.39
UCEC	chr22	30588074	Missense_Mutation	NA	D69Y	0.26	Pescadillo_N
UCEC	chr22	30587343	Missense_Mutation	novel	V104A	0.47	Pescadillo_N
UCEC	chr22	30589214	Silent	novel	L27L	0.32
UCEC	chr22	30589233	Missense_Mutation	rs150802010	N21S	0.5	Pescadillo_N

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.1642	0.00055806
THYM	DEL	0.0813	0.0035141
UCEC	AMP	0.0816	0.0010952

Survival Analysis

Cancer	P-value	Q-value
STAD	0.0038	Kaplan-Meier Survival Analysis
ACC	0.0016	Kaplan-Meier Survival Analysis
HNSC	0.0016	Kaplan-Meier Survival Analysis
LUSC	0.027	Kaplan-Meier Survival Analysis
PAAD	0.048	Kaplan-Meier Survival Analysis
PCPG	0.016	Kaplan-Meier Survival Analysis
READ	0.011	Kaplan-Meier Survival Analysis
LAML	0.0054	Kaplan-Meier Survival Analysis
LIHC	0.0001	Kaplan-Meier Survival Analysis
DLBC	0.025	Kaplan-Meier Survival Analysis
LGG	0.0028	Kaplan-Meier Survival Analysis
LUAD	0.00062	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

GWAS

PPI

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000100029 (Gene tree)
Gene ID: 23481
Gene Symbol: PES1
Alias: PES|NOP7
Full Name: pescadillo ribosomal biogenesis factor 1
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Minus strand
Length: 30,459 bases
Position: chr22:30,576,625-30,607,083
Accession: 8848
Summary: This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9. [provided by RefSeq, Aug 2011]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000334612	Pescadillo_N	PF06732.11	9.9e-126	1	1
ENSP00000346725	Pescadillo_N	PF06732.11	1e-125	1	1
ENSP00000384252	Pescadillo_N	PF06732.11	2.8e-107	1	1
ENSP00000384777	Pescadillo_N	PF06732.11	4.3e-53	1	1
ENSP00000384366	Pescadillo_N	PF06732.11	3.3e-52	1	1
ENSP00000385654	Pescadillo_N	PF06732.11	3.3e-52	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	polyT & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000467368	PES1-210	490	-	-	- (aa)	-	-
ENST00000477762	PES1-211	513	-	-	- (aa)	-	-
ENST00000406208	PES1-206	871	-	ENSP00000384777	135 (aa)	-	H7BYY8
ENST00000335214	PES1-201	1988	-	ENSP00000334612	583 (aa)	-	O00541
ENST00000405677	PES1-205	2708	-	ENSP00000385654	449 (aa)	-	B3KXD6
ENST00000354694	PES1-202	2295	XM_006724173	ENSP00000346725	588 (aa)	XP_006724236	O00541
ENST00000433575	PES1-207	560	-	-	- (aa)	-	-
ENST00000402281	PES1-203	2760	XM_017028678	ENSP00000384366	449 (aa)	XP_016884167	B3KXD6
ENST00000492986	PES1-213	630	-	-	- (aa)	-	-
ENST00000466614	PES1-209	713	-	-	- (aa)	-	-
ENST00000402284	PES1-204	2144	-	ENSP00000384252	571 (aa)	-	B5MCF9
ENST00000441668	PES1-208	999	-	ENSP00000404234	194 (aa)	-	H7C267
ENST00000488719	PES1-212	1732	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000100029's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000100029	rs5753231	22	30607082	T	Blood protein levels	29875488	[0.15-0.27] unit increase	0.21	EFO_0007937

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000100029's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000100029	PES1	100	77.941	ENSAPOG00000010054	pes	99	71.817	Acanthochromis_polyacanthus
ENSG00000100029	PES1	100	92.593	ENSAMEG00000007417	PES1	99	90.323	Ailuropoda_melanoleuca
ENSG00000100029	PES1	100	75.735	ENSACIG00000017610	pes	99	71.138	Amphilophus_citrinellus
ENSG00000100029	PES1	100	76.471	ENSAOCG00000008883	pes	99	70.458	Amphiprion_ocellaris
ENSG00000100029	PES1	100	77.206	ENSAPEG00000022652	pes	99	71.138	Amphiprion_percula
ENSG00000100029	PES1	98	69.861	ENSATEG00000007439	pes	99	69.297	Anabas_testudineus
ENSG00000100029	PES1	100	82.353	ENSAPLG00000014852	PES1	99	73.201	Anas_platyrhynchos
ENSG00000100029	PES1	100	81.618	ENSACAG00000009723	PES1	100	76.637	Anolis_carolinensis
ENSG00000100029	PES1	100	97.449	ENSANAG00000036411	PES1	100	97.449	Aotus_nancymaae
ENSG00000100029	PES1	93	83.889	ENSANAG00000021598	-	94	78.547	Aotus_nancymaae
ENSG00000100029	PES1	100	75.000	ENSACLG00000000815	pes	99	70.968	Astatotilapia_calliptera
ENSG00000100029	PES1	94	76.378	ENSAMXG00000001216	pes	99	64.103	Astyanax_mexicanus
ENSG00000100029	PES1	100	88.148	ENSBTAG00000007728	PES1	99	85.599	Bos_taurus
ENSG00000100029	PES1	84	52.632	WBGene00003063	lpd-7	81	51.121	Caenorhabditis_elegans
ENSG00000100029	PES1	100	97.279	ENSCJAG00000010617	PES1	100	97.279	Callithrix_jacchus
ENSG00000100029	PES1	100	94.074	ENSCAFG00000012792	PES1	99	89.286	Canis_familiaris
ENSG00000100029	PES1	100	94.074	ENSCAFG00020000977	PES1	99	89.438	Canis_lupus_dingo
ENSG00000100029	PES1	100	88.889	ENSCHIG00000015760	PES1	99	89.116	Capra_hircus
ENSG00000100029	PES1	100	93.333	ENSTSYG00000009798	PES1	99	92.845	Carlito_syrichta
ENSG00000100029	PES1	100	93.333	ENSCAPG00000007736	-	90	88.072	Cavia_aperea
ENSG00000100029	PES1	99	76.949	ENSCAPG00000012218	-	99	76.150	Cavia_aperea
ENSG00000100029	PES1	99	76.661	ENSCPOG00000022594	-	99	75.980	Cavia_porcellus
ENSG00000100029	PES1	100	91.304	ENSCPOG00000003565	-	99	89.831	Cavia_porcellus
ENSG00000100029	PES1	100	90.370	ENSCPOG00000039303	-	99	84.327	Cavia_porcellus
ENSG00000100029	PES1	100	96.088	ENSCCAG00000026457	PES1	100	96.088	Cebus_capucinus
ENSG00000100029	PES1	100	98.519	ENSCATG00000036948	PES1	100	98.305	Cercocebus_atys
ENSG00000100029	PES1	100	94.074	ENSCLAG00000010775	PES1	99	91.141	Chinchilla_lanigera
ENSG00000100029	PES1	100	98.519	ENSCSAG00000009207	PES1	100	98.472	Chlorocebus_sabaeus
ENSG00000100029	PES1	100	86.029	ENSCPBG00000007548	PES1	100	78.849	Chrysemys_picta_bellii
ENSG00000100029	PES1	100	97.789	ENSCANG00000039970	PES1	100	97.789	Colobus_angolensis_palliatus
ENSG00000100029	PES1	100	93.333	ENSCGRG00000015052	Pes1	97	92.697	Cricetulus_griseus_crigri
ENSG00000100029	PES1	100	73.529	ENSCSEG00000017612	pes	100	71.039	Cynoglossus_semilaevis
ENSG00000100029	PES1	100	77.941	ENSCVAG00000011600	pes	99	70.458	Cyprinodon_variegatus
ENSG00000100029	PES1	100	78.676	ENSDARG00000018902	pes	99	72.666	Danio_rerio
ENSG00000100029	PES1	100	93.333	ENSDNOG00000015709	-	99	91.141	Dasypus_novemcinctus
ENSG00000100029	PES1	98	68.586	ENSDNOG00000031909	-	99	59.686	Dasypus_novemcinctus
ENSG00000100029	PES1	100	92.593	ENSDORG00000016636	Pes1	100	90.214	Dipodomys_ordii
ENSG00000100029	PES1	96	48.507	FBgn0032138	CG4364	96	44.444	Drosophila_melanogaster
ENSG00000100029	PES1	54	86.722	ENSETEG00000007293	-	61	100.000	Echinops_telfairi
ENSG00000100029	PES1	100	69.630	ENSEBUG00000010234	pes	99	57.231	Eptatretus_burgeri
ENSG00000100029	PES1	95	71.048	ENSEASG00005010295	PES1	99	70.389	Equus_asinus_asinus
ENSG00000100029	PES1	100	92.593	ENSECAG00000002578	PES1	99	91.261	Equus_caballus
ENSG00000100029	PES1	100	77.941	ENSELUG00000003253	pes	99	71.501	Esox_lucius
ENSG00000100029	PES1	100	93.333	ENSFCAG00000008655	PES1	99	90.290	Felis_catus
ENSG00000100029	PES1	100	82.353	ENSFALG00000006909	PES1	99	74.866	Ficedula_albicollis
ENSG00000100029	PES1	100	92.593	ENSFDAG00000019029	PES1	99	90.847	Fukomys_damarensis
ENSG00000100029	PES1	100	77.941	ENSFHEG00000000287	pes	99	66.214	Fundulus_heteroclitus
ENSG00000100029	PES1	100	76.642	ENSGMOG00000013010	pes	99	70.085	Gadus_morhua
ENSG00000100029	PES1	100	83.824	ENSGALG00000007778	PES1	99	77.891	Gallus_gallus
ENSG00000100029	PES1	100	76.471	ENSGAFG00000012399	pes	99	70.458	Gambusia_affinis
ENSG00000100029	PES1	100	74.265	ENSGACG00000009302	pes	99	69.178	Gasterosteus_aculeatus
ENSG00000100029	PES1	100	86.765	ENSGAGG00000010897	PES1	100	79.188	Gopherus_agassizii
ENSG00000100029	PES1	100	99.150	ENSGGOG00000008530	PES1	100	99.150	Gorilla_gorilla
ENSG00000100029	PES1	99	82.051	ENSGGOG00000028472	-	100	74.024	Gorilla_gorilla
ENSG00000100029	PES1	100	75.000	ENSHBUG00000008000	pes	98	83.871	Haplochromis_burtoni
ENSG00000100029	PES1	100	92.593	ENSHGLG00000018472	PES1	99	90.339	Heterocephalus_glaber_female
ENSG00000100029	PES1	100	92.593	ENSHGLG00100004887	PES1	99	90.476	Heterocephalus_glaber_male
ENSG00000100029	PES1	100	75.735	ENSHCOG00000016666	pes	99	68.825	Hippocampus_comes
ENSG00000100029	PES1	100	77.941	ENSIPUG00000020261	pes1	99	70.819	Ictalurus_punctatus
ENSG00000100029	PES1	100	94.074	ENSSTOG00000013937	PES1	99	91.993	Ictidomys_tridecemlineatus
ENSG00000100029	PES1	100	80.000	ENSJJAG00000010640	-	96	83.333	Jaculus_jaculus
ENSG00000100029	PES1	100	93.333	ENSJJAG00000001782	-	99	91.312	Jaculus_jaculus
ENSG00000100029	PES1	100	77.206	ENSKMAG00000015285	pes	99	71.986	Kryptolebias_marmoratus
ENSG00000100029	PES1	98	68.586	ENSLBEG00000012366	pes	99	67.797	Labrus_bergylta
ENSG00000100029	PES1	100	81.618	ENSLACG00000017116	PES1	100	74.324	Latimeria_chalumnae
ENSG00000100029	PES1	98	66.310	ENSLOCG00000003935	pes	99	65.972	Lepisosteus_oculatus
ENSG00000100029	PES1	100	74.101	ENSLAFG00000022882	PES1	83	83.234	Loxodonta_africana
ENSG00000100029	PES1	100	98.519	ENSMFAG00000044708	PES1	100	98.469	Macaca_fascicularis
ENSG00000100029	PES1	100	98.639	ENSMMUG00000017562	PES1	100	98.639	Macaca_mulatta
ENSG00000100029	PES1	100	98.519	ENSMNEG00000029489	PES1	100	98.469	Macaca_nemestrina
ENSG00000100029	PES1	98	73.822	ENSMLEG00000030317	-	100	70.455	Mandrillus_leucophaeus
ENSG00000100029	PES1	100	98.519	ENSMLEG00000038584	PES1	100	98.472	Mandrillus_leucophaeus
ENSG00000100029	PES1	100	75.000	ENSMAMG00000014668	pes	99	70.339	Mastacembelus_armatus
ENSG00000100029	PES1	100	83.824	ENSMGAG00000014421	PES1	100	82.727	Meleagris_gallopavo
ENSG00000100029	PES1	100	94.074	ENSMAUG00000018433	Pes1	99	88.245	Mesocricetus_auratus
ENSG00000100029	PES1	99	93.186	ENSMICG00000010123	PES1	99	92.675	Microcebus_murinus
ENSG00000100029	PES1	100	93.333	ENSMOCG00000021971	Pes1	99	89.966	Microtus_ochrogaster
ENSG00000100029	PES1	98	63.368	ENSMMOG00000017812	pes	99	63.220	Mola_mola
ENSG00000100029	PES1	100	85.294	ENSMODG00000009483	PES1	99	81.633	Monodelphis_domestica
ENSG00000100029	PES1	100	75.000	ENSMALG00000012929	pes	99	70.890	Monopterus_albus
ENSG00000100029	PES1	100	92.593	MGP_CAROLIEiJ_G0016021	Pes1	99	84.327	Mus_caroli
ENSG00000100029	PES1	100	92.593	ENSMUSG00000020430	Pes1	99	89.097	Mus_musculus
ENSG00000100029	PES1	99	98.462	MGP_PahariEiJ_G0016870	-	99	90.290	Mus_pahari
ENSG00000100029	PES1	100	92.593	MGP_SPRETEiJ_G0016862	Pes1	99	86.869	Mus_spretus
ENSG00000100029	PES1	100	93.333	ENSMPUG00000012950	PES1	99	90.971	Mustela_putorius_furo
ENSG00000100029	PES1	100	94.815	ENSNGAG00000015282	Pes1	99	91.823	Nannospalax_galili
ENSG00000100029	PES1	100	75.735	ENSNBRG00000006301	pes	99	70.628	Neolamprologus_brichardi
ENSG00000100029	PES1	99	96.410	ENSNLEG00000003908	PES1	100	90.323	Nomascus_leucogenys
ENSG00000100029	PES1	100	83.704	ENSMEUG00000011656	PES1	99	77.296	Notamacropus_eugenii
ENSG00000100029	PES1	100	91.111	ENSOPRG00000000636	PES1	99	89.020	Ochotona_princeps
ENSG00000100029	PES1	100	94.815	ENSODEG00000003187	PES1	99	89.509	Octodon_degus
ENSG00000100029	PES1	100	75.000	ENSONIG00000013543	pes	99	72.156	Oreochromis_niloticus
ENSG00000100029	PES1	53	87.324	ENSOANG00000029840	-	84	87.324	Ornithorhynchus_anatinus
ENSG00000100029	PES1	92	72.778	ENSOANG00000012901	-	99	75.789	Ornithorhynchus_anatinus
ENSG00000100029	PES1	100	90.370	ENSOCUG00000009658	PES1	100	89.608	Oryctolagus_cuniculus
ENSG00000100029	PES1	98	77.444	ENSORLG00000007881	pes	99	70.187	Oryzias_latipes
ENSG00000100029	PES1	98	77.444	ENSORLG00020000368	pes	99	70.528	Oryzias_latipes_hni
ENSG00000100029	PES1	98	77.444	ENSORLG00015002220	pes	99	70.528	Oryzias_latipes_hsok
ENSG00000100029	PES1	100	75.735	ENSOMEG00000002922	pes	99	70.528	Oryzias_melastigma
ENSG00000100029	PES1	100	93.333	ENSOGAG00000005804	PES1	99	89.249	Otolemur_garnettii
ENSG00000100029	PES1	95	70.105	ENSOARG00000008214	PES1	100	72.727	Ovis_aries
ENSG00000100029	PES1	100	99.150	ENSPPAG00000029696	PES1	100	99.150	Pan_paniscus
ENSG00000100029	PES1	100	94.074	ENSPPRG00000024146	PES1	99	90.801	Panthera_pardus
ENSG00000100029	PES1	100	93.333	ENSPTIG00000021654	PES1	99	88.170	Panthera_tigris_altaica
ENSG00000100029	PES1	100	99.320	ENSPTRG00000014251	PES1	100	99.320	Pan_troglodytes
ENSG00000100029	PES1	100	69.634	ENSPTRG00000045557	-	100	69.459	Pan_troglodytes
ENSG00000100029	PES1	100	98.519	ENSPANG00000009607	PES1	99	98.472	Papio_anubis
ENSG00000100029	PES1	100	77.206	ENSPKIG00000024750	pes	99	69.580	Paramormyrops_kingsleyae
ENSG00000100029	PES1	98	70.732	ENSPMGG00000019024	pes	100	69.949	Periophthalmus_magnuspinnatus
ENSG00000100029	PES1	100	93.333	ENSPEMG00000012585	Pes1	99	88.644	Peromyscus_maniculatus_bairdii
ENSG00000100029	PES1	100	83.088	ENSPCIG00000023994	PES1	99	81.880	Phascolarctos_cinereus
ENSG00000100029	PES1	100	77.206	ENSPFOG00000014821	pes	99	70.847	Poecilia_formosa
ENSG00000100029	PES1	100	77.206	ENSPLAG00000003811	pes	99	71.017	Poecilia_latipinna
ENSG00000100029	PES1	100	77.206	ENSPMEG00000019878	pes	99	70.847	Poecilia_mexicana
ENSG00000100029	PES1	98	69.930	ENSPREG00000022586	pes	99	69.692	Poecilia_reticulata
ENSG00000100029	PES1	100	98.469	ENSPPYG00000011716	PES1	100	98.469	Pongo_abelii
ENSG00000100029	PES1	100	89.630	ENSPCAG00000011542	PES1	75	94.118	Procavia_capensis
ENSG00000100029	PES1	100	94.074	ENSPCOG00000016226	PES1	99	93.697	Propithecus_coquereli
ENSG00000100029	PES1	100	77.206	ENSPNAG00000020800	pes	99	70.307	Pygocentrus_nattereri
ENSG00000100029	PES1	100	92.593	ENSRNOG00000004515	Pes1	99	89.608	Rattus_norvegicus
ENSG00000100029	PES1	100	98.519	ENSRBIG00000040634	PES1	99	97.789	Rhinopithecus_bieti
ENSG00000100029	PES1	98	72.105	ENSRBIG00000034572	-	100	67.753	Rhinopithecus_bieti
ENSG00000100029	PES1	100	98.519	ENSRROG00000028779	PES1	100	97.959	Rhinopithecus_roxellana
ENSG00000100029	PES1	96	41.538	YGR103W	NOP7	97	39.836	Saccharomyces_cerevisiae
ENSG00000100029	PES1	100	96.429	ENSSBOG00000026073	PES1	100	96.429	Saimiri_boliviensis_boliviensis
ENSG00000100029	PES1	100	85.294	ENSSHAG00000002920	PES1	96	81.722	Sarcophilus_harrisii
ENSG00000100029	PES1	100	72.794	ENSSFOG00015005010	pes1	99	67.747	Scleropages_formosus
ENSG00000100029	PES1	100	75.000	ENSSMAG00000012102	pes	99	71.575	Scophthalmus_maximus
ENSG00000100029	PES1	100	76.471	ENSSDUG00000013213	pes	99	71.747	Seriola_dumerili
ENSG00000100029	PES1	100	76.471	ENSSLDG00000025373	pes	99	71.747	Seriola_lalandi_dorsalis
ENSG00000100029	PES1	100	83.088	ENSSPUG00000018150	PES1	100	77.157	Sphenodon_punctatus
ENSG00000100029	PES1	100	77.941	ENSSPAG00000018970	pes	99	71.477	Stegastes_partitus
ENSG00000100029	PES1	100	91.852	ENSSSCG00000010010	PES1	99	88.226	Sus_scrofa
ENSG00000100029	PES1	83	67.109	ENSTGUG00000015553	PES1	100	67.905	Taeniopygia_guttata
ENSG00000100029	PES1	100	71.111	ENSTRUG00000015909	pes	99	70.068	Takifugu_rubripes
ENSG00000100029	PES1	99	59.825	ENSTNIG00000015898	pes	99	59.649	Tetraodon_nigroviridis
ENSG00000100029	PES1	100	91.111	ENSTBEG00000009825	PES1	99	90.501	Tupaia_belangeri
ENSG00000100029	PES1	100	93.333	ENSTTRG00000001543	PES1	100	89.127	Tursiops_truncatus
ENSG00000100029	PES1	100	93.333	ENSUAMG00000006854	PES1	99	90.662	Ursus_americanus
ENSG00000100029	PES1	100	93.333	ENSUMAG00000016429	PES1	99	88.796	Ursus_maritimus
ENSG00000100029	PES1	100	94.074	ENSVVUG00000002684	-	99	88.586	Vulpes_vulpes
ENSG00000100029	PES1	100	93.333	ENSVVUG00000029961	-	99	86.542	Vulpes_vulpes
ENSG00000100029	PES1	99	65.529	ENSXETG00000030097	PES1	99	65.358	Xenopus_tropicalis
ENSG00000100029	PES1	89	80.000	ENSXCOG00000017009	pes	99	69.558	Xiphophorus_couchianus
ENSG00000100029	PES1	89	80.000	ENSXMAG00000007708	pes	99	69.218	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	21873635.	IBA	Process
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	16738141.17353269.	IMP	Process
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	16738141.	IMP	Process
GO:0000793	condensed chromosome	-	IEA	Component
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	16043514.16738141.17353269.25609649.25825154.30021884.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	16738141.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	16738141.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006364	rRNA processing	16738141.	IMP	Process
GO:0006364	rRNA processing	-	TAS	Process
GO:0007000	nucleolus organization	-	IEA	Process
GO:0008283	cell proliferation	16738141.	IMP	Process
GO:0008283	cell proliferation	16043514.	NAS	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0030687	preribosome, large subunit precursor	16738141.17353269.	IDA	Component
GO:0033365	protein localization to organelle	-	IEA	Process
GO:0042273	ribosomal large subunit biogenesis	16738141.17353269.	IC	Process
GO:0043021	ribonucleoprotein complex binding	-	IEA	Function
GO:0051726	regulation of cell cycle	16738141.	IMP	Process
GO:0070545	PeBoW complex	21873635.	IBA	Component
GO:0070545	PeBoW complex	16043514.16738141.17353269.	IDA	Component

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

GWAS

PPI

Ortholog

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.