EuRBPDB

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TCGA tumor abbreviations
  • ACCAdrenocortical carcinoma
  • BLCABladder Urothelial Carcinoma
  • BRCABreast invasive carcinoma
  • CESCCervical squamous cell carcinoma and endocervical adenocarcinoma
  • CHOLCholangio carcinoma
  • COADColon adenocarcinoma
  • DLBCLymphoid Neoplasm Diffuse Large B-cell Lymphoma
  • ESCAEsophageal carcinoma
  • GBMGlioblastoma multiforme
  • HNSCHead and Neck squamous cell carcinoma
  • KICHKidney Chromophobe
  • KIRCKidney renal clear cell carcinoma
  • KIRPKidney renal papillary cell carcinoma
  • LAMLAcute Myeloid Leukemia
  • LGGBrain Lower Grade Glioma
  • LIHCLiver hepatocellular carcinoma
  • LUADLung adenocarcinoma
  • LUSCLung squamous cell carcinoma
  • MESOMesothelioma
  • OVOvarian serous cystadenocarcinoma
  • PAADPancreatic adenocarcinoma
  • PCPGPheochromocytoma and Paraganglioma
  • PRADProstate adenocarcinoma
  • READRectum adenocarcinoma
  • SARCSarcoma
  • SKCMSkin Cutaneous Melanoma
  • STADStomach adenocarcinoma
  • TGCTThyroid carcinoma
  • THCAThyroid carcinoma
  • THYMThymoma
  • UCECUterine Corpus Endometrial Carcinoma
  • UCSUterine Carcinosarcoma
  • UVMUveal Melanoma

Note: Click here to get the extension of tumor abbreviations.


  • Cancer Related Information
  • Basic Information

Cancer associated literatures
PIDTitleArticle TimeAuthorDoi
23108393Sgk1 enhances RANBP1 transcript levels and decreases taxol sensitivity in RKO colon carcinoma cells.Oncogene2013 Sep 19Amato Rdoi: 10.1038/onc.2012.470

Differential Expression

Expression in 33 cancers

Mutations
CancerChrPosition Mutation TypedbSNPProtein-change Allele FreqRBD
BLCAchr2220119043Nonsense_MutationnovelE16*0.32
BLCAchr22201271023'UTRnovel0.27
BLCAchr2220122351Missense_MutationnovelH80Q0.33
BRCAchr2220126349Silentrs769969249I162I0.25
BRCAchr22201270983'UTRrs7753879520.21
CESCchr22201271813'UTRnovel0.59
CESCchr22201164265'Flanknovel0.41
CESCchr22201271603'UTRnovel0.37
COADchr2220122333SilentNAD74D0.42
COADchr2220125337Missense_Mutationrs771917916A114T0.28
COADchr22201270913'UTRrs7815740410.37
COADchr2220126340Missense_MutationNAR159S0.47
COADchr22201271023'UTRnovel0.12
COADchr2220127052Nonstop_MutationNA*202Yext*160.33
ESCAchr2220122303SilentnovelL64L0.35
GBMchr2220122406Missense_MutationnovelC99R0.7
GBMchr2220126337SilentnovelC158C0.08
KIRPchr2220122320Missense_MutationnovelR70Q0.15
KIRPchr2220122331Missense_MutationnovelD74Y0.36
LGGchr2220122269Missense_MutationnovelA53V0.35
LIHCchr22201270653'UTRnovel0.25
LUADchr2220122281Missense_MutationNAR57Q0.09
LUSCchr2220119119Missense_MutationnovelL41R0.05
LUSCchr22201270813'UTRnovel0.21
OVchr2220119102Missense_MutationnovelE35D0.83
OVchr2220119034Missense_MutationnovelT13A0.06
PAADchr2220125413Missense_MutationnovelA139V0.22
PRADchr22201270563'UTRrs5365667520.48
READchr2220126332Nonsense_MutationNAE157*0.51
SKCMchr2220126976Missense_MutationNAA177V0.44
SKCMchr22201270553'UTRnovel0.23
SKCMchr2220122375SilentNAL88L0.13
UCECchr2220122265Missense_MutationnovelR52W0.19
UCECchr2220127046SilentnovelK200K0.22
UCECchr2220119126SilentnovelE43E0.32
UCECchr2220126979Missense_Mutationrs756772977E178G0.28
UCECchr2220126349Silentrs769969249I162I0.44
UCECchr22201164215'Flanknovel0.43
UCECchr2220119071Missense_MutationNAP25R0.19
UCECchr2220126349Silentrs769969249I162I0.43
UCECchr2220122370Missense_MutationnovelR87C0.18
UCECchr2220127052Nonstop_MutationNA*202Yext*160.32
UCECchr22201270913'UTRnovel0.52
UCECchr2220119081SilentnovelE28E0.17
UCECchr2220126317Frame_Shift_DelnovelT153Qfs*320.39
UCECchr2220119045Missense_MutationNAE16D0.32
UCECchr22201270713'UTRnovel0.28

Copy Number Variations (CNVs)
CancerTypeFreq Q-value
LUSCAMP0.38922.9109e-05
LUSCDEL0.11780.0093511
TGCTAMP0.35335.309e-06
THCAAMP0.0080.056221

Survival Analysis
CancerP-value Q-value
THYM0.0084

Kaplan-Meier Survival Analysis

KIRC0.0013

Kaplan-Meier Survival Analysis

STAD0.0084

Kaplan-Meier Survival Analysis

SARC0.0038

Kaplan-Meier Survival Analysis

MESO0.041

Kaplan-Meier Survival Analysis

ACC0.00019

Kaplan-Meier Survival Analysis

HNSC0.022

Kaplan-Meier Survival Analysis

SKCM0.014

Kaplan-Meier Survival Analysis

LUSC0.00084

Kaplan-Meier Survival Analysis

PAAD0.022

Kaplan-Meier Survival Analysis

PCPG0.032

Kaplan-Meier Survival Analysis

READ0.021

Kaplan-Meier Survival Analysis

UCEC0.022

Kaplan-Meier Survival Analysis

GBM0.013

Kaplan-Meier Survival Analysis

LIHC0.0001

Kaplan-Meier Survival Analysis

DLBC0.025

Kaplan-Meier Survival Analysis

LGG0.024

Kaplan-Meier Survival Analysis

LUAD0.0035

Kaplan-Meier Survival Analysis

OV0.011

Kaplan-Meier Survival Analysis

Drugs

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Eesembl ID



Cell lines and drugs in GSE70138 or GSE92742

  • Description
  • RBPome
  • Expression
  • Transcripts
  • Gene Model
  • Pathways
  • PPI
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000099901 (Gene tree)
Gene ID
5902
Gene Symbol
RANBP1
Alias
HTF9A
Full Name
RAN binding protein 1
Gene Type
protein_coding
Species
Homo_sapiens
Status
putative
Strand
Plus strand
Length
11,420 bases
Position
chr22:20,115,938-20,127,357
Accession
9847
RBP type
non-canonical RBP
Summary
This gene encodes a protein that forms a complex with Ras-related nuclear protein (Ran) and metabolizes guanoside triphosphate (GTP). This complex participates in the regulation of the cell cycle by controlling transport of proteins and nucleic acids into the nucleus. There are multiple pseudogenes for this gene on chromosomes 9, 12, 17, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & MCF72018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & U2OS2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000432879RANBP1-209744-ENSP00000404724165 (aa)-C9JDM3
ENST00000423859RANBP1-207832XM_017028891ENSP00000404298204 (aa)XP_016884380C9JGV6
ENST00000435265RANBP1-2101879-ENSP0000039013973 (aa)-F8WCY3
ENST00000488484RANBP1-214699--- (aa)--
ENST00000418705RANBP1-205932XM_011530291ENSP00000413502145 (aa)XP_011528593C9JXG8
ENST00000421656RANBP1-206333-ENSP0000040094053 (aa)-C9JIC6
ENST00000402752RANBP1-2021132XM_011530290ENSP00000384925200 (aa)XP_011528592P43487
ENST00000416427RANBP1-204645-ENSP0000040412653 (aa)-C9JIC6
ENST00000430524RANBP1-2081389-ENSP00000401564278 (aa)-F6WQW2
ENST00000411892RANBP1-203584XM_011530289ENSP00000395472163 (aa)XP_011528591C9JJ34
ENST00000448394RANBP1-211688--- (aa)--
ENST00000486575RANBP1-2132177--- (aa)--
ENST00000331821RANBP1-201837-ENSP00000327583201 (aa)-P43487
ENST00000467920RANBP1-212529--- (aa)--
Gene Model
Click here to download ENSG00000099901's gene model file
Pathways
Pathway IDPathway NameSource
hsa05166Human T-cell leukemia virus 1 infectionKEGG
hsa05203Viral carcinogenesisKEGG
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000099901's network

* RBP PPI network refers to all genes directly bind to RBP
Orthologs identified by RBPome
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000099901RANBP110098.113ENSMUSG00000005732Ranbp19894.975Mus_musculus
ENSG00000099901RANBP19869.231YDR002WYRB17753.797Saccharomyces_cerevisiae
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0005092GDP-dissociation inhibitor activity7616957.IMPFunction
GO:0005096GTPase activator activity21873635.IBAFunction
GO:0005515protein binding7616957.16428860.IPIFunction
GO:0005634nucleus21873635.IBAComponent
GO:0005634nucleus16130169.TASComponent
GO:0005635nuclear envelope-TASComponent
GO:0005643nuclear pore21873635.IBAComponent
GO:0005737cytoplasm21873635.IBAComponent
GO:0005737cytoplasm25743254.IDAComponent
GO:0005737cytoplasm16130169.TASComponent
GO:0005813centrosome21873635.IBAComponent
GO:0005829cytosol-IDAComponent
GO:0007165signal transduction16130169.TASProcess
GO:0008536Ran GTPase binding21873635.IBAFunction
GO:0016032viral process-TASProcess
GO:0043547positive regulation of GTPase activity-IEAProcess
GO:0045296cadherin binding25468996.HDAFunction
GO:0046604positive regulation of mitotic centrosome separation21873635.IBAProcess
GO:0046907intracellular transport-IEAProcess
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