EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
19436308	The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer.	Br J Cancer	2009 May 19	Shah R	doi: 10.1038/sj.bjc.6605042.
29956121	Identification of an enhancer region within the TP63/LEPREL1 locus containing genetic variants associated with bladder cancer risk.	Cell Oncol (Dordr)	2018 Oct	Dudek AM	doi: 10.1007/s13402-018-0393-5

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr3	189987531	Missense_Mutation	novel	R365T	0.58
BLCA	chr3	189988976	Missense_Mutation	rs774186462	G296R	0.5
BLCA	chr3	189995313	Missense_Mutation	novel	D204H	0.25
BLCA	chr3	189994217	Missense_Mutation	rs752928706	E234K	0.57
BLCA	chr3	189970887	Missense_Mutation	novel	L608V	0.17	2OG-FeII_Oxy
BLCA	chr3	189987581	Silent	novel	Y348Y	0.38
BLCA	chr3	189988941	Silent	novel	L307L	0.29
BLCA	chr3	189957939	Silent	novel	L700L	0.15
BLCA	chr3	189973015	Missense_Mutation	NA	E520K	0.5
BLCA	chr3	189986860	Silent	novel	V372V	0.12
BLCA	chr3	189972915	Missense_Mutation	NA	Y553C	0.62
BRCA	chr3	189987664	Missense_Mutation	NA	E321K	0.4
BRCA	chr3	189984592	Splice_Site	novel	X397_splice	0.3
BRCA	chr3	189994159	Missense_Mutation	NA	G253V	0.32
BRCA	chr3	189986877	Missense_Mutation	NA	D367H	0.11
BRCA	chr3	189974602	Missense_Mutation	rs143768603	V470I	0.22
BRCA	chr3	189987607	Nonsense_Mutation	novel	E340*	0.26
BRCA	chr3	189971923	Missense_Mutation	rs778738955	K595T	0.1
BRCA	chr3	189957938	Missense_Mutation	novel	N701H	0.09
BRCA	chr3	189988958	Missense_Mutation	NA	E302Q	0.22
BRCA	chr3	189983061	Nonsense_Mutation	NA	R437*	0.13
CESC	chr3	189988981	Missense_Mutation	rs377087463	R294H	0.48
CESC	chr3	189989002	Missense_Mutation	novel	C287Y	0.44
CESC	chr3	189957901	3'UTR	novel		0.31
CESC	chr3	189994145	Missense_Mutation	NA	E258Q	0.27
CESC	chr3	190120287	Missense_Mutation	novel	V149L	0.42
CESC	chr3	189973914	Missense_Mutation	novel	L515F	0.35
CESC	chr3	189995358	Missense_Mutation	NA	E189Q	0.19
CESC	chr3	189994190	Missense_Mutation	rs376765314	E243K	0.16
CESC	chr3	189987548	Silent	rs761021603	P359P	0.83
CESC	chr3	189972976	Missense_Mutation	novel	D533N	0.16
CHOL	chr3	189972995	Missense_Mutation	novel	K526N	0.71
COAD	chr3	189995398	Frame_Shift_Ins	NA	*V176Rfs3**	0.25
COAD	chr3	189972993	Missense_Mutation	NA	S527I	0.39
COAD	chr3	189964067	Missense_Mutation	NA	I642T	0.28	2OG-FeII_Oxy
COAD	chr3	189957912	Nonstop_Mutation	novel	709Yext2	0.34
COAD	chr3	190120367	Missense_Mutation	novel	S122N	0.42
COAD	chr3	189984570	Silent	novel	G403G	0.07
COAD	chr3	189958006	Splice_Site	NA	X679_splice	0.4
COAD	chr3	189994194	Silent	NA	F241F	0.53
COAD	chr3	189995344	Silent	rs377052077	A193A	0.33
COAD	chr3	189972888	Missense_Mutation	rs376010445	R562Q	0.21
ESCA	chr3	189970863	Nonsense_Mutation	novel	E616*	0.41	2OG-FeII_Oxy
ESCA	chr3	190120347	Missense_Mutation	rs200731219	G129W	0.35
ESCA	chr3	189974619	Missense_Mutation	rs537288155	R464Q	0.32
GBM	chr3	189983061	Nonsense_Mutation	NA	R437*	0.33
GBM	chr3	189986788	Splice_Region	rs749183285	P396P	0.27
GBM	chr3	189983141	Splice_Site	NA	X410_splice	0.3
GBM	chr3	189963967	Silent	rs578158144	Y675Y	0.48
HNSC	chr3	189964014	Missense_Mutation	novel	G660R	0.16	2OG-FeII_Oxy
HNSC	chr3	189957901	3'UTR	novel		0.23
HNSC	chr3	189970841	Missense_Mutation	novel	T623I	0.23	2OG-FeII_Oxy
HNSC	chr3	189984549	Splice_Site	novel	X410_splice	0.24
KIRC	chr3	189971982	Silent	NA	L575L	0.14
LGG	chr3	189974653	Missense_Mutation	rs780112859	V453I	0.34
LGG	chr3	189987634	Missense_Mutation	NA	A331S	0.22
LIHC	chr3	189974006	Splice_Site	NA	X485_splice	0.45
LIHC	chr3	189972892	Missense_Mutation	NA	C561R	0.43
LIHC	chr3	190120345	Silent	NA	G129G	0.35
LIHC	chr3	189983046	Missense_Mutation	NA	G442S	0.07
LUAD	chr3	189995443	Splice_Site	novel	X161_splice	0.11
LUAD	chr3	189994095	Splice_Region	novel	A274A	0.08
LUAD	chr3	190120348	Silent	novel	L128L	0.19
LUAD	chr3	189994136	Nonsense_Mutation	novel	E261*	0.07
LUAD	chr3	189963991	Silent	novel	L667L	0.08
LUAD	chr3	190120327	Missense_Mutation	novel	H135Q	0.3
LUSC	chr3	189984565	Missense_Mutation	rs757331420	R405Q	0.14
LUSC	chr3	189974653	Missense_Mutation	rs780112859	V453I	0.07
LUSC	chr3	189963966	Nonsense_Mutation	novel	R676*	0.06
LUSC	chr3	189994224	Missense_Mutation	NA	R231S	0.19
LUSC	chr3	189971912	Missense_Mutation	novel	A599T	0.41	2OG-FeII_Oxy
LUSC	chr3	189957948	Frame_Shift_Del	novel	*G696Afs2**	0.08
LUSC	chr3	189983103	Missense_Mutation	NA	H423Y	0.04
LUSC	chr3	189957977	Missense_Mutation	novel	A688T	0.11
LUSC	chr3	189974620	Missense_Mutation	rs750783069	R464W	0.1
LUSC	chr3	189973021	Missense_Mutation	novel	G518C	0.58
LUSC	chr3	189987604	Missense_Mutation	rs373927327	D341N	0.37
LUSC	chr3	189957869	3'UTR	novel		0.56
OV	chr3	190120282	Silent	NA	P150P	0.2
PCPG	chr3	189987547	Missense_Mutation	novel	A360T	0.08
PCPG	chr3	189986806	Silent	rs767283538	G390G	0.06
READ	chr3	189994218	Silent	rs114077778	F233F	0.27
READ	chr3	189984576	Silent	novel	R401R	0.07
READ	chr3	189995345	Missense_Mutation	rs780816013	A193V	0.32
READ	chr3	189995430	Missense_Mutation	rs756832334	E165K	0.34
READ	chr3	189995431	Silent	rs778714232	L164L	0.36
SARC	chr3	189972883	Missense_Mutation	NA	A564T	0.16
SKCM	chr3	189972000	Silent	NA	Q569Q	0.41
SKCM	chr3	189986801	Missense_Mutation	novel	S392L	0.22
SKCM	chr3	189971995	Missense_Mutation	novel	R571K	0.17
SKCM	chr3	189983125	Silent	novel	V415V	0.2
SKCM	chr3	189974595	Missense_Mutation	rs777721300	S472L	0.59
SKCM	chr3	189974654	Silent	rs267599731	F452F	0.1
SKCM	chr3	189988994	Missense_Mutation	NA	E290K	0.32
SKCM	chr3	189964013	Missense_Mutation	novel	G660E	0.36	2OG-FeII_Oxy
SKCM	chr3	189972000	Silent	NA	Q569Q	0.33
SKCM	chr3	189983125	Silent	novel	V415V	0.29
SKCM	chr3	189957951	Silent	NA	G696G	0.24
SKCM	chr3	189971948	Missense_Mutation	NA	D587N	0.3
SKCM	chr3	189995356	Silent	NA	E189E	0.36
SKCM	chr3	189971926	Nonsense_Mutation	novel	W594*	0.6
SKCM	chr3	189994218	Silent	rs114077778	F233F	0.27
SKCM	chr3	189973942	Silent	NA	K505K	0.33
SKCM	chr3	189983132	Missense_Mutation	NA	S413L	0.28
SKCM	chr3	189994194	Silent	NA	F241F	0.16
SKCM	chr3	189974654	Silent	rs267599731	F452F	0.36
SKCM	chr3	189984551	Missense_Mutation	NA	R410W	0.43
SKCM	chr3	189973973	Missense_Mutation	NA	G495E	0.41
SKCM	chr3	189995376	Missense_Mutation	NA	E183K	0.39
SKCM	chr3	189972909	Missense_Mutation	NA	S555F	0.43
SKCM	chr3	189983137	Silent	novel	V411V	0.48
SKCM	chr3	189973961	Missense_Mutation	NA	P499L	0.1
SKCM	chr3	189988949	Missense_Mutation	NA	L305F	0.25
SKCM	chr3	189994283	Missense_Mutation	NA	E212K	0.18
SKCM	chr3	189972958	Nonsense_Mutation	NA	R539*	0.28
SKCM	chr3	189984579	Silent	novel	I400I	0.41
SKCM	chr3	189987566	Silent	rs544815805	L353L	0.25
SKCM	chr3	189986814	Missense_Mutation	NA	G388S	0.35
SKCM	chr3	189995398	Silent	rs567532723	F175F	0.46
SKCM	chr3	189972909	Missense_Mutation	NA	S555F	0.33
SKCM	chr3	189974654	Silent	rs267599731	F452F	0.32
SKCM	chr3	189995398	Silent	rs567532723	F175F	0.12
SKCM	chr3	189974004	Missense_Mutation	rs754236871	G485R	0.57
SKCM	chr3	189974590	Missense_Mutation	NA	E474K	0.54
SKCM	chr3	189987607	Missense_Mutation	rs115909080	E340K	0.23
SKCM	chr3	189972954	Missense_Mutation	novel	R540K	0.71
SKCM	chr3	189964066	Silent	NA	I642I	0.49
SKCM	chr3	189986838	Missense_Mutation	NA	E380K	0.19
SKCM	chr3	189963978	Missense_Mutation	novel	D672N	0.27
SKCM	chr3	189983060	Missense_Mutation	novel	R437Q	0.35
SKCM	chr3	189983075	Missense_Mutation	rs771139030	S432L	0.34
SKCM	chr3	189994150	Missense_Mutation	NA	R256K	0.24
SKCM	chr3	189995398	Silent	rs567532723	F175F	0.39
SKCM	chr3	189970834	Missense_Mutation	NA	M625I	0.21	2OG-FeII_Oxy
SKCM	chr3	190120293	Missense_Mutation	rs575702697	R147C	0.23
SKCM	chr3	189984591	Splice_Site	novel	X397_splice	0.39
SKCM	chr3	189970849	Silent	rs370201984	F620F	0.28
SKCM	chr3	189995429	Missense_Mutation	rs753266253	E165G	0.31
SKCM	chr3	189994218	Silent	rs114077778	F233F	0.2
SKCM	chr3	189984551	Missense_Mutation	NA	R410W	0.2
SKCM	chr3	189964013	Missense_Mutation	novel	G660E	0.53	2OG-FeII_Oxy
SKCM	chr3	189964014	Missense_Mutation	novel	G660R	0.52	2OG-FeII_Oxy
SKCM	chr3	189983066	Missense_Mutation	novel	I435K	0.34
SKCM	chr3	189984565	Missense_Mutation	rs757331420	R405Q	0.23
SKCM	chr3	189971899	Missense_Mutation	rs374266006	R603Q	0.16	2OG-FeII_Oxy
SKCM	chr3	189972878	Silent	novel	L565L	0.39
SKCM	chr3	189994210	Missense_Mutation	novel	A236V	0.14
SKCM	chr3	189986806	Silent	NA	G390G	0.33
SKCM	chr3	189987628	Missense_Mutation	NA	L333F	0.19
STAD	chr3	189972922	Missense_Mutation	NA	T551P	0.25
STAD	chr3	189973972	Silent	NA	G495G	0.11
STAD	chr3	189983061	Nonsense_Mutation	NA	R437*	0.33
STAD	chr3	189984565	Missense_Mutation	rs757331420	R405Q	0.25
STAD	chr3	189983073	Missense_Mutation	novel	P433S	0.29
STAD	chr3	189957947	Missense_Mutation	NA	H698D	0.11
STAD	chr3	189994217	Missense_Mutation	rs752928706	E234K	0.33
STAD	chr3	189964097	Missense_Mutation	rs558211251	A632V	0.13	2OG-FeII_Oxy
STAD	chr3	189957980	Missense_Mutation	NA	I687V	0.18
STAD	chr3	189994184	Missense_Mutation	NA	T245A	0.35
STAD	chr3	190120265	Missense_Mutation	NA	R156Q	0.64
STAD	chr3	189971996	Missense_Mutation	rs776013018	R571G	0.15
THCA	chr3	189994106	Nonsense_Mutation	novel	E271*	0.09
THYM	chr3	189964074	Missense_Mutation	rs758007118	R640C	0.2	2OG-FeII_Oxy
UCEC	chr3	189988952	Missense_Mutation	NA	F304V	0.32
UCEC	chr3	189994142	Nonsense_Mutation	NA	E259*	0.3
UCEC	chr3	189995431	Silent	rs778714232	L164L	0.35
UCEC	chr3	189957742	3'UTR	novel		0.42
UCEC	chr3	189964042	Silent	novel	N650N	0.07
UCEC	chr3	189995398	Silent	rs567532723	F175F	0.25
UCEC	chr3	189994194	Silent	NA	F241F	0.25
UCEC	chr3	189972895	Missense_Mutation	novel	V560I	0.42
UCEC	chr3	189983051	Missense_Mutation	novel	R440I	0.33
UCEC	chr3	189974619	Missense_Mutation	rs537288155	R464Q	0.36
UCEC	chr3	189987656	Silent	NA	V323V	0.44
UCEC	chr3	189957882	3'UTR	novel		0.32
UCEC	chr3	189994217	Missense_Mutation	rs752928706	E234K	0.49
UCEC	chr3	189972958	Nonsense_Mutation	NA	R539*	0.44
UCEC	chr3	189995345	Missense_Mutation	rs780816013	A193V	0.49
UCEC	chr3	189972967	Missense_Mutation	rs545810582	E536K	0.08
UCEC	chr3	189988987	Missense_Mutation	NA	A292V	0.16
UCEC	chr3	189986835	Missense_Mutation	NA	L381M	0.36
UCEC	chr3	189983104	Silent	novel	V422V	0.18
UCEC	chr3	189957901	3'UTR	novel		0.45
UCEC	chr3	189970854	Nonsense_Mutation	novel	E619*	0.19	2OG-FeII_Oxy
UCEC	chr3	189995307	Nonsense_Mutation	novel	E206*	0.3
UCEC	chr3	189995398	Silent	rs567532723	F175F	0.3
UCEC	chr3	189994260	Silent	NA	K219K	0.16
UCEC	chr3	189994217	Missense_Mutation	rs752928706	E234K	0.58
UCEC	chr3	189984551	Splice_Region	novel	R410R	0.39
UCEC	chr3	189974652	Missense_Mutation	novel	V453A	0.33
UCEC	chr3	189984551	Missense_Mutation	NA	R410W	0.35
UCEC	chr3	189995431	Silent	rs778714232	L164L	0.48
UCEC	chr3	189957726	3'UTR	novel		0.29
UCEC	chr3	189995398	Silent	rs567532723	F175F	0.25
UCEC	chr3	189995431	Silent	rs778714232	L164L	0.53
UCEC	chr3	189973982	Missense_Mutation	novel	G492E	0.4
UCEC	chr3	189986855	Missense_Mutation	novel	R374H	0.26
UCEC	chr3	189957894	3'UTR	novel		0.04
UCEC	chr3	189973994	Missense_Mutation	novel	L488P	0.11
UCEC	chr3	189957856	3'UTR	novel		0.41
UCEC	chr3	190120324	Silent	NA	R136R	0.45
UCEC	chr3	189957835	3'UTR	novel		0.37
UCEC	chr3	189970870	Silent	NA	D613D	0.5
UCEC	chr3	189973940	Missense_Mutation	novel	F506C	0.1
UCEC	chr3	189988958	Missense_Mutation	rs748750473	E302K	0.5
UCEC	chr3	189974585	Missense_Mutation	novel	Q475H	0.66
UCEC	chr3	189974587	Missense_Mutation	novel	Q475E	0.67
UCEC	chr3	189957962	Nonsense_Mutation	NA	E693*	0.31
UCEC	chr3	189973983	Missense_Mutation	novel	G492R	0.37
UCEC	chr3	189984551	Missense_Mutation	NA	R410W	0.24
UCEC	chr3	189988970	Missense_Mutation	novel	L298F	0.36
UCEC	chr3	189995345	Missense_Mutation	rs780816013	A193V	0.29
UCEC	chr3	189972003	Silent	NA	Q568Q	0.37
UCEC	chr3	189964070	Missense_Mutation	NA	M641T	0.28	2OG-FeII_Oxy
UCEC	chr3	189994137	Nonsense_Mutation	novel	Y260*	0.25
UCS	chr3	189964073	Missense_Mutation	rs765123377	R640L	0.41	2OG-FeII_Oxy

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.4338	0.0018563
KIRC	AMP	0.1174	2.0306e-05
KIRP	AMP	0.3194	0.15981
LUAD	DEL	0.1822	0.010111
PAAD	AMP	0.1087	0.16151
SARC	DEL	0.1634	0.0086757
TGCT	AMP	0.2533	7.0307e-05

Survival Analysis

Cancer	P-value	Q-value
STAD	0.0039	Kaplan-Meier Survival Analysis
MESO	0.00017	Kaplan-Meier Survival Analysis
ACC	0.019	Kaplan-Meier Survival Analysis
UCS	0.015	Kaplan-Meier Survival Analysis
SKCM	0.011	Kaplan-Meier Survival Analysis
ESCA	0.025	Kaplan-Meier Survival Analysis
PAAD	0.0012	Kaplan-Meier Survival Analysis
KICH	0.05	Kaplan-Meier Survival Analysis
UCEC	0.0076	Kaplan-Meier Survival Analysis
GBM	0.0034	Kaplan-Meier Survival Analysis
LGG	0.00012	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000090530 (Gene tree)
Gene ID: 55214
Gene Symbol: P3H2
Alias: FLJ10718|MLAT4|LEPREL1
Full Name: prolyl 3-hydroxylase 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 165,710 bases
Position: chr3:189,956,728-190,122,437
Accession: 19317
RBP type: canonical RBP
Summary: This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000408947	2OG-FeII_Oxy	PF03171.20	8.7e-09	1	1
ENSP00000316881	2OG-FeII_Oxy	PF03171.20	1.5e-08	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000444866	P3H2-204	544	-	ENSP00000391374	137 (aa)	-	C9J313
ENST00000482780	P3H2-209	893	-	-	- (aa)	-	-
ENST00000463171	P3H2-205	754	-	-	- (aa)	-	-
ENST00000475095	P3H2-208	552	-	-	- (aa)	-	-
ENST00000427335	P3H2-203	2963	XM_011512955	ENSP00000408947	527 (aa)	XP_011511257	Q8IVL5
ENST00000467131	P3H2-206	554	-	-	- (aa)	-	-
ENST00000319332	P3H2-201	3509	-	ENSP00000316881	708 (aa)	-	Q8IVL5
ENST00000470925	P3H2-207	583	-	-	- (aa)	-	-
ENST00000490940	P3H2-210	472	-	-	- (aa)	-	-
ENST00000426003	P3H2-202	609	-	ENSP00000394326	134 (aa)	-	C9JSL4

Gene Model

Click here to download ENSG00000090530's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000090530	Blood Pressure	8.92867062781078E-5	17903302
ENSG00000090530	Blood Pressure	7.6855409045791E-5	17903302
ENSG00000090530	Blood Pressure	7.78253244468834E-5	17903302
ENSG00000090530	Transferrin	7.557e-005	-
ENSG00000090530	Calcium	9.6780000E-005	-
ENSG00000090530	Blood Pressure	2.9863061E-005	-
ENSG00000090530	Platelet Function Tests	2.6693100E-005	-
ENSG00000090530	Platelet Function Tests	1.6268000E-005	-
ENSG00000090530	Platelet Function Tests	1.7823000E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000090530	rs13319406	3	190118647	G	Itch intensity from mosquito bite adjusted by bite size	28199695	[0.019-0.046] unit increase	0.0324478	EFO_0008377\|EFO_0008378
ENSG00000090530	rs2030571	3	190104301	T	Facial morphology (factor 16)	28441456	[0.18-0.43] unit increase	0.3081	EFO_0007841
ENSG00000090530	rs3106806	3	190103894	C	Nicotine dependence and major depression (severity of comorbidity)	30287806	[0.74-1.81] unit decrease	1.2707	EFO_0009262\|EFO_0007006
ENSG00000090530	rs9882792	3	190056667	T	Breast cancer	29059683	[0.022-0.053] unit decrease	0.0377	EFO_0000305

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000090530's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000090530	P3H2	99	62.667	ENSAPOG00000021463	p3h2	100	62.667	Acanthochromis_polyacanthus
ENSG00000090530	P3H2	100	90.892	ENSAMEG00000000726	P3H2	100	89.661	Ailuropoda_melanoleuca
ENSG00000090530	P3H2	100	62.429	ENSACIG00000012482	p3h2	96	59.701	Amphilophus_citrinellus
ENSG00000090530	P3H2	83	65.217	ENSAOCG00000006595	p3h2	96	65.217	Amphiprion_ocellaris
ENSG00000090530	P3H2	100	61.860	ENSAPEG00000006169	p3h2	96	59.281	Amphiprion_percula
ENSG00000090530	P3H2	100	62.239	ENSATEG00000009514	p3h2	96	59.132	Anabas_testudineus
ENSG00000090530	P3H2	100	96.774	ENSANAG00000021430	P3H2	100	94.640	Aotus_nancymaae
ENSG00000090530	P3H2	100	61.480	ENSACLG00000020074	p3h2	96	59.104	Astatotilapia_calliptera
ENSG00000090530	P3H2	100	62.619	ENSAMXG00000017679	p3h2	96	58.832	Astyanax_mexicanus
ENSG00000090530	P3H2	100	95.636	ENSBTAG00000021025	P3H2	100	92.655	Bos_taurus
ENSG00000090530	P3H2	100	97.154	ENSCJAG00000014239	P3H2	100	94.789	Callithrix_jacchus
ENSG00000090530	P3H2	100	94.877	ENSCAFG00000013985	P3H2	100	91.139	Canis_familiaris
ENSG00000090530	P3H2	100	94.877	ENSCAFG00020020127	P3H2	100	91.139	Canis_lupus_dingo
ENSG00000090530	P3H2	100	93.928	ENSCHIG00000011298	P3H2	100	91.384	Capra_hircus
ENSG00000090530	P3H2	100	96.774	ENSTSYG00000008652	P3H2	100	96.774	Carlito_syrichta
ENSG00000090530	P3H2	100	87.591	ENSCAPG00000012826	P3H2	100	79.091	Cavia_aperea
ENSG00000090530	P3H2	100	90.892	ENSCPOG00000004329	P3H2	95	90.182	Cavia_porcellus
ENSG00000090530	P3H2	100	97.154	ENSCCAG00000034046	P3H2	100	94.225	Cebus_capucinus
ENSG00000090530	P3H2	100	98.861	ENSCATG00000004107	P3H2	100	98.023	Cercocebus_atys
ENSG00000090530	P3H2	100	92.410	ENSCLAG00000012801	P3H2	100	90.500	Chinchilla_lanigera
ENSG00000090530	P3H2	100	98.672	ENSCSAG00000009034	P3H2	100	98.023	Chlorocebus_sabaeus
ENSG00000090530	P3H2	82	97.368	ENSCHOG00000013468	P3H2	82	97.368	Choloepus_hoffmanni
ENSG00000090530	P3H2	100	78.748	ENSCPBG00000012789	P3H2	97	78.832	Chrysemys_picta_bellii
ENSG00000090530	P3H2	100	98.861	ENSCANG00000017978	P3H2	99	98.851	Colobus_angolensis_palliatus
ENSG00000090530	P3H2	100	92.979	ENSCGRG00001021764	P3h2	97	90.393	Cricetulus_griseus_chok1gshd
ENSG00000090530	P3H2	100	92.789	ENSCGRG00000009640	P3h2	98	92.219	Cricetulus_griseus_crigri
ENSG00000090530	P3H2	100	62.239	ENSCSEG00000013736	p3h2	95	59.880	Cynoglossus_semilaevis
ENSG00000090530	P3H2	100	61.670	ENSCVAG00000020470	p3h2	96	58.383	Cyprinodon_variegatus
ENSG00000090530	P3H2	100	62.239	ENSDARG00000103026	p3h2	100	62.286	Danio_rerio
ENSG00000090530	P3H2	100	94.118	ENSDNOG00000035205	P3H2	100	90.819	Dasypus_novemcinctus
ENSG00000090530	P3H2	100	93.169	ENSDORG00000001518	P3h2	100	90.704	Dipodomys_ordii
ENSG00000090530	P3H2	100	95.446	ENSEASG00005000187	P3H2	100	91.949	Equus_asinus_asinus
ENSG00000090530	P3H2	100	96.015	ENSECAG00000008971	P3H2	100	92.514	Equus_caballus
ENSG00000090530	P3H2	100	96.015	ENSFCAG00000000791	P3H2	100	92.948	Felis_catus
ENSG00000090530	P3H2	100	71.904	ENSFALG00000007377	P3H2	100	70.256	Ficedula_albicollis
ENSG00000090530	P3H2	100	63.188	ENSFHEG00000007209	p3h2	95	60.030	Fundulus_heteroclitus
ENSG00000090530	P3H2	100	61.815	ENSGMOG00000009134	p3h2	100	61.815	Gadus_morhua
ENSG00000090530	P3H2	100	78.368	ENSGALG00000040866	P3H2	96	75.373	Gallus_gallus
ENSG00000090530	P3H2	100	62.808	ENSGAFG00000013603	p3h2	96	60.180	Gambusia_affinis
ENSG00000090530	P3H2	100	62.075	ENSGACG00000010066	p3h2	100	62.075	Gasterosteus_aculeatus
ENSG00000090530	P3H2	100	78.748	ENSGAGG00000025337	-	86	74.707	Gopherus_agassizii
ENSG00000090530	P3H2	100	99.431	ENSGGOG00000009749	P3H2	100	98.596	Gorilla_gorilla
ENSG00000090530	P3H2	99	56.061	ENSHBUG00000022967	p3h2	100	54.753	Haplochromis_burtoni
ENSG00000090530	P3H2	100	90.702	ENSHGLG00000019175	P3H2	97	87.083	Heterocephalus_glaber_female
ENSG00000090530	P3H2	100	56.204	ENSHCOG00000019274	p3h2	97	53.892	Hippocampus_comes
ENSG00000090530	P3H2	99	60.381	ENSIPUG00000016970	p3h2	99	56.560	Ictalurus_punctatus
ENSG00000090530	P3H2	100	94.497	ENSSTOG00000006501	P3H2	100	91.243	Ictidomys_tridecemlineatus
ENSG00000090530	P3H2	100	91.651	ENSJJAG00000013941	P3h2	95	91.289	Jaculus_jaculus
ENSG00000090530	P3H2	100	62.998	ENSKMAG00000022098	p3h2	98	59.763	Kryptolebias_marmoratus
ENSG00000090530	P3H2	100	62.998	ENSLBEG00000003942	p3h2	98	59.232	Labrus_bergylta
ENSG00000090530	P3H2	100	69.754	ENSLACG00000014642	P3H2	96	65.522	Latimeria_chalumnae
ENSG00000090530	P3H2	100	65.844	ENSLOCG00000005129	p3h2	96	62.575	Lepisosteus_oculatus
ENSG00000090530	P3H2	100	93.738	ENSLAFG00000007727	P3H2	100	93.333	Loxodonta_africana
ENSG00000090530	P3H2	100	98.861	ENSMFAG00000036104	P3H2	100	98.023	Macaca_fascicularis
ENSG00000090530	P3H2	100	98.672	ENSMMUG00000000623	P3H2	100	97.881	Macaca_mulatta
ENSG00000090530	P3H2	100	98.861	ENSMNEG00000027261	P3H2	100	98.023	Macaca_nemestrina
ENSG00000090530	P3H2	99	61.524	ENSMAMG00000006370	p3h2	100	61.524	Mastacembelus_armatus
ENSG00000090530	P3H2	100	61.480	ENSMZEG00005003110	p3h2	96	59.104	Maylandia_zebra
ENSG00000090530	P3H2	100	77.609	ENSMGAG00000007491	P3H2	100	77.413	Meleagris_gallopavo
ENSG00000090530	P3H2	100	92.600	ENSMAUG00000004803	P3h2	97	89.956	Mesocricetus_auratus
ENSG00000090530	P3H2	100	96.964	ENSMICG00000049208	P3H2	100	93.644	Microcebus_murinus
ENSG00000090530	P3H2	100	93.359	ENSMOCG00000008061	P3h2	97	90.830	Microtus_ochrogaster
ENSG00000090530	P3H2	100	61.290	ENSMMOG00000019576	p3h2	96	58.832	Mola_mola
ENSG00000090530	P3H2	97	68.750	ENSMODG00000015073	P3H2	95	63.529	Monodelphis_domestica
ENSG00000090530	P3H2	100	62.049	ENSMALG00000017825	p3h2	96	58.683	Monopterus_albus
ENSG00000090530	P3H2	100	92.220	MGP_CAROLIEiJ_G0020626	P3h2	97	90.102	Mus_caroli
ENSG00000090530	P3H2	100	92.220	ENSMUSG00000038168	P3h2	97	90.102	Mus_musculus
ENSG00000090530	P3H2	100	93.169	MGP_PahariEiJ_G0016331	P3h2	97	91.121	Mus_pahari
ENSG00000090530	P3H2	100	92.030	MGP_SPRETEiJ_G0021522	P3h2	97	89.942	Mus_spretus
ENSG00000090530	P3H2	99	95.812	ENSMPUG00000003446	P3H2	88	95.812	Mustela_putorius_furo
ENSG00000090530	P3H2	100	93.750	ENSMLUG00000015613	P3H2	100	93.455	Myotis_lucifugus
ENSG00000090530	P3H2	100	92.410	ENSNGAG00000000626	P3h2	98	85.358	Nannospalax_galili
ENSG00000090530	P3H2	100	59.583	ENSNBRG00000016641	p3h2	97	57.463	Neolamprologus_brichardi
ENSG00000090530	P3H2	100	98.861	ENSNLEG00000006734	-	100	98.861	Nomascus_leucogenys
ENSG00000090530	P3H2	100	93.169	ENSOPRG00000014074	P3H2	100	89.873	Ochotona_princeps
ENSG00000090530	P3H2	100	61.101	ENSONIG00000001714	p3h2	96	58.358	Oreochromis_niloticus
ENSG00000090530	P3H2	94	85.170	ENSOANG00000013797	P3H2	99	85.170	Ornithorhynchus_anatinus
ENSG00000090530	P3H2	100	94.687	ENSOCUG00000011014	P3H2	100	91.842	Oryctolagus_cuniculus
ENSG00000090530	P3H2	100	61.101	ENSORLG00000005641	p3h2	96	58.383	Oryzias_latipes
ENSG00000090530	P3H2	100	56.716	ENSORLG00020021674	p3h2	95	57.878	Oryzias_latipes_hni
ENSG00000090530	P3H2	100	61.290	ENSORLG00015019012	p3h2	96	58.533	Oryzias_latipes_hsok
ENSG00000090530	P3H2	100	61.670	ENSOMEG00000013713	p3h2	96	59.132	Oryzias_melastigma
ENSG00000090530	P3H2	100	93.585	ENSOGAG00000003842	P3H2	100	93.466	Otolemur_garnettii
ENSG00000090530	P3H2	100	93.785	ENSOARG00000020475	P3H2	100	91.292	Ovis_aries
ENSG00000090530	P3H2	100	99.431	ENSPPAG00000040013	P3H2	95	99.506	Pan_paniscus
ENSG00000090530	P3H2	100	95.825	ENSPPRG00000014656	P3H2	100	92.525	Panthera_pardus
ENSG00000090530	P3H2	100	95.825	ENSPTIG00000016608	P3H2	84	95.784	Panthera_tigris_altaica
ENSG00000090530	P3H2	100	99.435	ENSPTRG00000015736	P3H2	100	99.435	Pan_troglodytes
ENSG00000090530	P3H2	100	98.672	ENSPANG00000005379	P3H2	100	97.881	Papio_anubis
ENSG00000090530	P3H2	100	62.239	ENSPMGG00000012834	p3h2	97	59.431	Periophthalmus_magnuspinnatus
ENSG00000090530	P3H2	100	92.789	ENSPEMG00000016547	P3h2	97	90.379	Peromyscus_maniculatus_bairdii
ENSG00000090530	P3H2	100	63.378	ENSPFOG00000014376	p3h2	96	60.479	Poecilia_formosa
ENSG00000090530	P3H2	100	63.188	ENSPLAG00000012556	p3h2	96	60.329	Poecilia_latipinna
ENSG00000090530	P3H2	100	62.998	ENSPMEG00000010685	p3h2	95	60.180	Poecilia_mexicana
ENSG00000090530	P3H2	100	60.721	ENSPREG00000015431	p3h2	96	57.485	Poecilia_reticulata
ENSG00000090530	P3H2	100	94.118	ENSPVAG00000009057	P3H2	100	91.549	Pteropus_vampyrus
ENSG00000090530	P3H2	100	61.670	ENSPNYG00000005890	p3h2	96	59.254	Pundamilia_nyererei
ENSG00000090530	P3H2	100	62.619	ENSPNAG00000029093	p3h2	97	59.552	Pygocentrus_nattereri
ENSG00000090530	P3H2	100	92.979	ENSRNOG00000055751	P3h2	97	90.262	Rattus_norvegicus
ENSG00000090530	P3H2	100	98.861	ENSRBIG00000018185	P3H2	100	98.164	Rhinopithecus_bieti
ENSG00000090530	P3H2	100	98.861	ENSRROG00000031164	P3H2	100	97.881	Rhinopithecus_roxellana
ENSG00000090530	P3H2	100	95.620	ENSSBOG00000035056	P3H2	100	93.453	Saimiri_boliviensis_boliviensis
ENSG00000090530	P3H2	96	66.535	ENSSHAG00000006714	-	100	65.146	Sarcophilus_harrisii
ENSG00000090530	P3H2	100	63.757	ENSSFOG00015006816	p3h2	96	61.377	Scleropages_formosus
ENSG00000090530	P3H2	100	62.998	ENSSMAG00000003284	p3h2	95	60.329	Scophthalmus_maximus
ENSG00000090530	P3H2	100	63.567	ENSSDUG00000002767	p3h2	96	59.731	Seriola_dumerili
ENSG00000090530	P3H2	100	63.567	ENSSLDG00000017365	p3h2	96	59.731	Seriola_lalandi_dorsalis
ENSG00000090530	P3H2	100	70.896	ENSSPUG00000010809	P3H2	98	64.222	Sphenodon_punctatus
ENSG00000090530	P3H2	100	61.290	ENSSPAG00000021635	p3h2	96	58.533	Stegastes_partitus
ENSG00000090530	P3H2	100	95.446	ENSSSCG00000011813	P3H2	100	92.514	Sus_scrofa
ENSG00000090530	P3H2	100	76.850	ENSTGUG00000009345	P3H2	100	76.545	Taeniopygia_guttata
ENSG00000090530	P3H2	100	62.429	ENSTRUG00000017655	p3h2	96	59.581	Takifugu_rubripes
ENSG00000090530	P3H2	100	61.480	ENSTNIG00000015540	p3h2	100	61.566	Tetraodon_nigroviridis
ENSG00000090530	P3H2	100	87.591	ENSTBEG00000004997	P3H2	100	78.511	Tupaia_belangeri
ENSG00000090530	P3H2	100	92.220	ENSTTRG00000001893	P3H2	100	91.091	Tursiops_truncatus
ENSG00000090530	P3H2	100	91.971	ENSUAMG00000006549	P3H2	98	90.221	Ursus_americanus
ENSG00000090530	P3H2	100	95.825	ENSUMAG00000003698	P3H2	97	95.733	Ursus_maritimus
ENSG00000090530	P3H2	100	86.338	ENSVPAG00000012351	P3H2	100	86.903	Vicugna_pacos
ENSG00000090530	P3H2	100	94.877	ENSVVUG00000013454	P3H2	99	92.122	Vulpes_vulpes
ENSG00000090530	P3H2	100	69.565	ENSXETG00000012845	p3h2	100	69.550	Xenopus_tropicalis
ENSG00000090530	P3H2	100	61.101	ENSXCOG00000002798	p3h2	97	58.445	Xiphophorus_couchianus
ENSG00000090530	P3H2	100	62.239	ENSXMAG00000018362	p3h2	96	59.431	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005506	iron ion binding	-	IEA	Function
GO:0005604	basement membrane	-	ISS	Component
GO:0005783	endoplasmic reticulum	21873635.	IBA	Component
GO:0005783	endoplasmic reticulum	15063763.	IDA	Component
GO:0005788	endoplasmic reticulum lumen	-	TAS	Component
GO:0005794	Golgi apparatus	15063763.	IDA	Component
GO:0008285	negative regulation of cell proliferation	19436308.	IDA	Process
GO:0016529	sarcoplasmic reticulum	-	IEA	Component
GO:0019511	peptidyl-proline hydroxylation	18487197.	IDA	Process
GO:0019797	procollagen-proline 3-dioxygenase activity	21873635.	IBA	Function
GO:0019797	procollagen-proline 3-dioxygenase activity	18487197.	IDA	Function
GO:0031418	L-ascorbic acid binding	-	IEA	Function
GO:0032963	collagen metabolic process	21873635.	IBA	Process
GO:0032963	collagen metabolic process	18487197.	IDA	Process
GO:0055114	oxidation-reduction process	-	IEA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.