EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
17973258	Expression of alpha CP-4 inhibits cell cycle progression and suppresses tumorigenicity of lung cancer cells.	Int J Cancer	2008 Apr 1	Castao Z	-

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr3	51958332	Missense_Mutation	novel	S314C	0.23
BLCA	chr3	51960193	Missense_Mutation	rs774406552	R128Q	0.21
BLCA	chr3	51960186	Splice_Region	novel		0.37
BLCA	chr3	51960856	Intron	novel		0.43
BLCA	chr3	51960698	Intron	novel		0.34
BLCA	chr3	51959919	Silent	novel	R164R	0.19
BLCA	chr3	51958087	Missense_Mutation	novel	E396K	0.3
BLCA	chr3	51960064	Intron	novel		0.06
BRCA	chr3	51958937	Missense_Mutation	rs753153356	R259H	0.37
BRCA	chr3	51961158	Splice_Site	novel	X27_splice	0.1
CESC	chr3	51957886	3'UTR	novel		0.16
CESC	chr3	51960015	Frame_Shift_Ins	novel	*A133Mfs57**	0.05
CESC	chr3	51958007	3'UTR	novel		0.4
COAD	chr3	51959909	Missense_Mutation	rs746354848	A168T	0.22
COAD	chr3	51960662	Intron	rs775990120		0.33
COAD	chr3	51961300	5'UTR	rs749932268		0.1
COAD	chr3	51960545	Missense_Mutation	novel	I79T	0.11
COAD	chr3	51958082	Silent	NA	R397R	0.35
COAD	chr3	51959397	Frame_Shift_Ins	novel	*G203Efs11**	0.1
COAD	chr3	51961300	5'UTR	rs749932268		0.13
HNSC	chr3	51958901	Missense_Mutation	novel	S271L	0.19
HNSC	chr3	51960812	Intron	NA		0.1
HNSC	chr3	51959270	Nonsense_Mutation	novel	S220*	0.3
KIRP	chr3	51960236	Missense_Mutation	NA	G114S	0.2
LGG	chr3	51958863	Missense_Mutation	novel	A284P	0.12
LGG	chr3	51959261	Missense_Mutation	rs780942022	A223V	0.3
LIHC	chr3	51959946	Silent	NA	V155V	0.22
LUAD	chr3	51960769	Intron	novel		0.11
LUAD	chr3	51960283	Missense_Mutation	novel	S98C	0.19
LUSC	chr3	51960766	Intron	novel		0.19
LUSC	chr3	51960631	Silent	novel	R50R	0.5
OV	chr3	51960609	Missense_Mutation	novel	C58S	0.21
PRAD	chr3	51959238	Missense_Mutation	rs773787182	V231M	0.23
PRAD	chr3	51958283	Silent	novel	P330P	0.15
READ	chr3	51960267	Silent	rs755532537	T103T	0.66
SARC	chr3	51958834	Silent	novel	G293G	0.16
SKCM	chr3	51960251	Missense_Mutation	rs767718245	P109S	0.33
SKCM	chr3	51960252	Silent	novel	I108I	0.45
SKCM	chr3	51960035	Intron	NA		0.33
SKCM	chr3	51958921	Silent	novel	I264I	0.29
SKCM	chr3	51960610	Silent	NA	S57S	0.3
SKCM	chr3	51961230	Missense_Mutation	rs765205448	S4L	0.65
SKCM	chr3	51958248	Missense_Mutation	NA	P342L	0.37
SKCM	chr3	51957993	3'UTR	novel		0.24
STAD	chr3	51960790	Intron	novel		0.05
STAD	chr3	51960155	Intron	rs745620970		0.3
STAD	chr3	51960555	Missense_Mutation	NA	V76I	0.14
STAD	chr3	51957930	3'UTR	novel		0.45
STAD	chr3	51961180	Missense_Mutation	rs778090769	R21W	0.32	KH_1
STAD	chr3	51958114	Missense_Mutation	novel	A387T	0.37
STAD	chr3	51958862	Missense_Mutation	novel	A284G	0.31
STAD	chr3	51958854	Missense_Mutation	NA	R287W	0.14
STAD	chr3	51957946	3'UTR	novel		0.15
STAD	chr3	51958245	Frame_Shift_Del	novel	*P343Lfs65**	0.39
STAD	chr3	51959958	Silent	rs753730306	T151T	0.19
STAD	chr3	51959921	Missense_Mutation	NA	R164C	0.11
STAD	chr3	51961016	Silent	rs138501114	I33I	0.09
UCEC	chr3	51960668	Intron	novel		0.19
UCEC	chr3	51960866	Splice_Region	novel	Q46Q	0.26
UCEC	chr3	51961023	Missense_Mutation	novel	S31I	0.35	KH_1
UCEC	chr3	51959959	Missense_Mutation	rs142190169	T151M	0.67
UCEC	chr3	51958818	Missense_Mutation	novel	A299T	0.37
UCEC	chr3	51958202	Missense_Mutation	novel	F357L	0.21
UCEC	chr3	51960869	Missense_Mutation	novel	E45D	0.18	KH_1
UCEC	chr3	51961204	Nonsense_Mutation	NA	E13*	0.29
UCEC	chr3	51957666	3'UTR	novel		0.38
UCEC	chr3	51959616	Silent	novel	P184P	0.07
UCEC	chr3	51961179	Missense_Mutation	novel	R21Q	0.35	KH_1
UCEC	chr3	51958220	Silent	NA	A351A	0.04
UCEC	chr3	51958287	Missense_Mutation	novel	A329G	0.4
UCEC	chr3	51958142	Silent	rs553215873	P377P	0.42
UCEC	chr3	51960599	Missense_Mutation	NA	R61H	0.51
UCEC	chr3	51958215	Missense_Mutation	NA	S353F	0.43
UCEC	chr3	51957798	3'UTR	rs766715004		0.38
UCEC	chr3	51957569	3'UTR	novel		0.32
UCEC	chr3	51957550	3'UTR	novel		0.37
UCEC	chr3	51960599	Missense_Mutation	NA	R61H	0.5
UCEC	chr3	51958156	Missense_Mutation	novel	P373T	0.38
UCEC	chr3	51960661	Intron	NA		0.4
UCEC	chr3	51958133	Silent	novel	A380A	0.14
UCEC	chr3	51959293	Splice_Site	novel	X213_splice	0.22
UCEC	chr3	51957608	3'UTR	novel		0.44

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CHOL	DEL	0.7778	0.016387
GBM	DEL	0.0815	0.056565
LGG	DEL	0.0819	0.00089193
LUAD	DEL	0.3295	0.0021265
PAAD	DEL	0.1848	0.030662
SARC	DEL	0.2218	0.0034746
SKCM	DEL	0.1662	0.13887
TGCT	AMP	0.1467	0.23596
THYM	DEL	0.0813	0.037527

Survival Analysis

Cancer	P-value	Q-value
THYM	0.017	Kaplan-Meier Survival Analysis
SARC	0.00071	Kaplan-Meier Survival Analysis
MESO	0.0051	Kaplan-Meier Survival Analysis
ACC	0.0014	Kaplan-Meier Survival Analysis
HNSC	0.043	Kaplan-Meier Survival Analysis
GBM	0.0084	Kaplan-Meier Survival Analysis
LIHC	0.00081	Kaplan-Meier Survival Analysis
LGG	0.00011	Kaplan-Meier Survival Analysis
LUAD	0.013	Kaplan-Meier Survival Analysis
UVM	0.00074	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000090097 (Gene tree)
Gene ID: 57060
Gene Symbol: PCBP4
Alias: MCG10|LIP4
Full Name: poly(rC) binding protein 4
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 16,563 bases
Position: chr3:51,957,454-51,974,016
Accession: 8652
RBP type: canonical RBP
Summary: This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000418925	KH_1	PF00013.29	2.6e-50	1	3
ENSP00000418925	KH_1	PF00013.29	2.6e-50	2	3
ENSP00000418925	KH_1	PF00013.29	2.6e-50	3	3
ENSP00000322341	KH_1	PF00013.29	7e-50	1	3
ENSP00000322341	KH_1	PF00013.29	7e-50	2	3
ENSP00000322341	KH_1	PF00013.29	7e-50	3	3
ENSP00000348111	KH_1	PF00013.29	7e-50	1	3
ENSP00000348111	KH_1	PF00013.29	7e-50	2	3
ENSP00000348111	KH_1	PF00013.29	7e-50	3	3
ENSP00000417196	KH_1	PF00013.29	7e-50	1	3
ENSP00000417196	KH_1	PF00013.29	7e-50	2	3
ENSP00000417196	KH_1	PF00013.29	7e-50	3	3
ENSP00000395030	KH_1	PF00013.29	3.9e-41	1	3
ENSP00000395030	KH_1	PF00013.29	3.9e-41	2	3
ENSP00000395030	KH_1	PF00013.29	3.9e-41	3	3
ENSP00000417100	KH_1	PF00013.29	3.9e-41	1	3
ENSP00000417100	KH_1	PF00013.29	3.9e-41	2	3
ENSP00000417100	KH_1	PF00013.29	3.9e-41	3	3
ENSP00000419694	KH_1	PF00013.29	3e-32	1	2
ENSP00000419694	KH_1	PF00013.29	3e-32	2	2
ENSP00000419557	KH_1	PF00013.29	5.5e-20	1	1
ENSP00000418312	KH_1	PF00013.29	2.8e-15	1	1
ENSP00000420008	KH_1	PF00013.29	3.3e-15	1	1
ENSP00000417916	KH_1	PF00013.29	5e-15	1	1
ENSP00000418997	KH_1	PF00013.29	1.5e-13	1	1
ENSP00000419672	KH_1	PF00013.29	2.2e-06	1	1
ENSP00000418925	KH_2	PF07650.17	9.5e-15	1	1
ENSP00000322341	KH_2	PF07650.17	2.7e-14	1	1
ENSP00000348111	KH_2	PF07650.17	2.7e-14	1	1
ENSP00000417196	KH_2	PF07650.17	2.7e-14	1	1
ENSP00000419694	KH_2	PF07650.17	8.2e-12	1	1
ENSP00000419557	KH_2	PF07650.17	6.8e-08	1	1
ENSP00000418997	KH_2	PF07650.17	0.00016	1	1
ENSP00000418312	KH_2	PF07650.17	0.00017	1	1
ENSP00000420008	KH_2	PF07650.17	0.0002	1	1
ENSP00000417916	KH_2	PF07650.17	0.00027	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
10891498	MCG10, a novel p53 target gene that encodes a KH domain RNA-binding protein, is capable of inducing apoptosis and cell cycle arrest in G(2)-M.	Mol Cell Biol	2000 Aug	Zhu J	-
15205328	Alpha CP-4, encoded by a putative tumor suppressor gene at 3p21, but not its alternative splice variant alpha CP-4a, is underexpressed in lung cancer.	Cancer Res	2004 Jun 15	Pio R	-
17973258	Expression of alpha CP-4 inhibits cell cycle progression and suppresses tumorigenicity of lung cancer cells.	Int J Cancer	2008 Apr 1	Castano Z	-
20817677	The cyclin-dependent kinase inhibitor p21 is regulated by RNA-binding protein PCBP4 via mRNA stability.	Nucleic Acids Res	2011 Jan	Scoumanne A	doi: 10.1093/nar/gkq778
21799254	Forty years of the 93D puff of Drosophila melanogaster.	J Biosci	2011 Aug	Lakhotia SC	-
26005159	Gender-specific association between the cytoplasmic poly(A) binding protein 4 rs4660293 single nucleotide polymorphism and serum lipid levels.	Mol Med Rep	2015 Sep	Wu J	doi: 10.3892/mmr.2015.3823
22884093	Cytoplasmic poly(A) binding protein 4 is highly expressed in human colorectal cancer and correlates with better prognosis.	J Genet Genomics	2012 Aug 20	Liu D	doi: 10.1016/j.jgg.2012.05.007
15021911	The RNA binding protein Sam68 is acetylated in tumor cell lines, and its acetylation correlates with enhanced RNA binding activity.	Oncogene	2004 May 6	Babic I	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000471308	PCBP4-208	2087	-	ENSP00000418613	57 (aa)	-	F8WC71
ENST00000484633	PCBP4-212	2009	XM_006713270	ENSP00000417100	360 (aa)	XP_006713333	P57723
ENST00000483411	PCBP4-211	563	-	ENSP00000418997	74 (aa)	-	C9IZV9
ENST00000497653	PCBP4-217	559	-	ENSP00000417916	106 (aa)	-	C9J5V4
ENST00000466412	PCBP4-206	837	-	ENSP00000419557	124 (aa)	-	C9JTY5
ENST00000461554	PCBP4-205	2147	XM_006713269	ENSP00000417196	403 (aa)	XP_006713332	P57723
ENST00000468324	PCBP4-207	704	-	ENSP00000419694	168 (aa)	-	C9JZY3
ENST00000461544	PCBP4-204	562	-	ENSP00000419672	46 (aa)	-	C9K0A2
ENST00000492809	PCBP4-215	2599	-	-	- (aa)	-	-
ENST00000498822	PCBP4-218	2547	-	-	- (aa)	-	-
ENST00000428823	PCBP4-203	1835	-	ENSP00000395030	360 (aa)	-	P57723
ENST00000490063	PCBP4-214	510	-	ENSP00000418312	86 (aa)	-	C9J7A9
ENST00000322099	PCBP4-201	1964	XM_005265331	ENSP00000322341	403 (aa)	XP_005265388	P57723
ENST00000471622	PCBP4-210	1784	XM_017006918	ENSP00000418925	323 (aa)	XP_016862407	C9J0A4
ENST00000489595	PCBP4-213	539	-	ENSP00000420008	91 (aa)	-	C9JSA6
ENST00000497390	PCBP4-216	2434	-	-	- (aa)	-	-
ENST00000355852	PCBP4-202	2015	XM_024453682	ENSP00000348111	403 (aa)	XP_024309450	P57723
ENST00000471358	PCBP4-209	559	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000090097's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000090097	rs323877	3	51965447	G	Macrophage inflammatory protein 1b levels	27989323	[0.07-0.137] SD units increase	0.1034	EFO_0008219

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000090097's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000090097	PCBP4	89	41.538	ENSG00000139910	NOVA1	72	36.709
ENSG00000090097	PCBP4	92	70.130	ENSG00000197111	PCBP2	94	69.799
ENSG00000090097	PCBP4	100	30.303	ENSG00000088247	KHSRP	99	35.616
ENSG00000090097	PCBP4	89	30.597	ENSG00000159217	IGF2BP1	59	30.597
ENSG00000090097	PCBP4	97	68.712	ENSG00000169564	PCBP1	98	52.691
ENSG00000090097	PCBP4	93	31.034	ENSG00000073792	IGF2BP2	68	32.800
ENSG00000090097	PCBP4	91	37.037	ENSG00000162613	FUBP1	59	36.000
ENSG00000090097	PCBP4	75	36.000	ENSG00000107164	FUBP3	60	41.270
ENSG00000090097	PCBP4	92	74.026	ENSG00000183570	PCBP3	91	74.026
ENSG00000090097	PCBP4	88	30.909	ENSG00000104967	NOVA2	58	41.538
ENSG00000090097	PCBP4	89	32.468	ENSG00000165119	HNRNPK	83	45.902

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000090097	PCBP4	86	72.840	ENSAPOG00000018462	-	68	76.623	Acanthochromis_polyacanthus
ENSG00000090097	PCBP4	98	74.390	ENSAPOG00000009897	-	96	57.399	Acanthochromis_polyacanthus
ENSG00000090097	PCBP4	100	99.405	ENSAMEG00000009211	PCBP4	100	98.015	Ailuropoda_melanoleuca
ENSG00000090097	PCBP4	95	74.359	ENSACIG00000015264	pcbp4	89	53.538	Amphilophus_citrinellus
ENSG00000090097	PCBP4	95	76.000	ENSACIG00000020434	-	100	56.627	Amphilophus_citrinellus
ENSG00000090097	PCBP4	98	64.024	ENSAOCG00000021366	-	98	53.363	Amphiprion_ocellaris
ENSG00000090097	PCBP4	89	77.885	ENSAOCG00000006924	-	99	56.941	Amphiprion_ocellaris
ENSG00000090097	PCBP4	89	77.358	ENSAPEG00000023157	pcbp4	100	57.183	Amphiprion_percula
ENSG00000090097	PCBP4	98	64.024	ENSAPEG00000009555	-	88	46.875	Amphiprion_percula
ENSG00000090097	PCBP4	97	64.072	ENSATEG00000006511	-	98	53.642	Anabas_testudineus
ENSG00000090097	PCBP4	95	69.565	ENSATEG00000008529	pcbp4	93	54.847	Anabas_testudineus
ENSG00000090097	PCBP4	100	91.781	ENSACAG00000011701	PCBP4	100	78.606	Anolis_carolinensis
ENSG00000090097	PCBP4	100	100.000	ENSANAG00000023072	PCBP4	100	99.752	Aotus_nancymaae
ENSG00000090097	PCBP4	92	79.870	ENSACLG00000013348	pcbp4	94	53.715	Astatotilapia_calliptera
ENSG00000090097	PCBP4	97	75.000	ENSACLG00000025246	-	96	57.623	Astatotilapia_calliptera
ENSG00000090097	PCBP4	97	76.074	ENSAMXG00000033125	pcbp4	96	57.582	Astyanax_mexicanus
ENSG00000090097	PCBP4	100	99.405	ENSBTAG00000018622	PCBP4	100	97.519	Bos_taurus
ENSG00000090097	PCBP4	100	100.000	ENSCJAG00000005783	PCBP4	100	99.752	Callithrix_jacchus
ENSG00000090097	PCBP4	100	99.405	ENSCAFG00000010019	PCBP4	100	98.015	Canis_familiaris
ENSG00000090097	PCBP4	100	99.405	ENSCAFG00020022361	PCBP4	100	98.015	Canis_lupus_dingo
ENSG00000090097	PCBP4	100	99.405	ENSCHIG00000012918	PCBP4	100	97.767	Capra_hircus
ENSG00000090097	PCBP4	100	99.405	ENSTSYG00000008765	PCBP4	100	98.759	Carlito_syrichta
ENSG00000090097	PCBP4	100	98.214	ENSCAPG00000005895	PCBP4	100	96.774	Cavia_aperea
ENSG00000090097	PCBP4	100	98.214	ENSCPOG00000014617	PCBP4	100	97.519	Cavia_porcellus
ENSG00000090097	PCBP4	100	100.000	ENSCCAG00000033268	PCBP4	100	99.504	Cebus_capucinus
ENSG00000090097	PCBP4	100	100.000	ENSCATG00000032034	PCBP4	100	99.504	Cercocebus_atys
ENSG00000090097	PCBP4	100	98.214	ENSCLAG00000008356	PCBP4	100	97.767	Chinchilla_lanigera
ENSG00000090097	PCBP4	100	100.000	ENSCSAG00000013913	PCBP4	100	99.504	Chlorocebus_sabaeus
ENSG00000090097	PCBP4	99	94.521	ENSCPBG00000016554	PCBP4	97	79.567	Chrysemys_picta_bellii
ENSG00000090097	PCBP4	100	100.000	ENSCANG00000038865	PCBP4	100	99.504	Colobus_angolensis_palliatus
ENSG00000090097	PCBP4	100	98.214	ENSCGRG00001014953	Pcbp4	100	97.270	Cricetulus_griseus_chok1gshd
ENSG00000090097	PCBP4	100	98.214	ENSCGRG00000008617	Pcbp4	100	97.270	Cricetulus_griseus_crigri
ENSG00000090097	PCBP4	97	61.963	ENSCSEG00000021041	PCBP4	98	51.786	Cynoglossus_semilaevis
ENSG00000090097	PCBP4	90	78.289	ENSCSEG00000014487	pcbp4	93	52.575	Cynoglossus_semilaevis
ENSG00000090097	PCBP4	95	73.171	ENSCVAG00000003674	pcbp4	98	60.955	Cyprinodon_variegatus
ENSG00000090097	PCBP4	97	74.233	ENSCVAG00000013090	-	96	57.175	Cyprinodon_variegatus
ENSG00000090097	PCBP4	97	76.074	ENSDARG00000024276	pcbp4	99	63.354	Danio_rerio
ENSG00000090097	PCBP4	100	98.837	ENSDNOG00000033951	PCBP4	90	98.824	Dasypus_novemcinctus
ENSG00000090097	PCBP4	100	98.901	ENSDORG00000000573	Pcbp4	100	97.270	Dipodomys_ordii
ENSG00000090097	PCBP4	81	89.085	ENSETEG00000001778	PCBP4	96	98.810	Echinops_telfairi
ENSG00000090097	PCBP4	100	98.901	ENSEASG00005012889	PCBP4	100	97.022	Equus_asinus_asinus
ENSG00000090097	PCBP4	100	98.901	ENSECAG00000024218	PCBP4	100	97.022	Equus_caballus
ENSG00000090097	PCBP4	92	78.571	ENSELUG00000018204	pcbp4	97	57.672	Esox_lucius
ENSG00000090097	PCBP4	97	74.233	ENSELUG00000001870	-	96	55.507	Esox_lucius
ENSG00000090097	PCBP4	100	99.405	ENSFCAG00000009148	PCBP4	100	98.263	Felis_catus
ENSG00000090097	PCBP4	92	92.647	ENSFALG00000008831	PCBP4	90	79.625	Ficedula_albicollis
ENSG00000090097	PCBP4	100	97.022	ENSFDAG00000012692	PCBP4	100	97.619	Fukomys_damarensis
ENSG00000090097	PCBP4	94	75.000	ENSFHEG00000002769	-	97	49.584	Fundulus_heteroclitus
ENSG00000090097	PCBP4	95	79.167	ENSGMOG00000017799	-	98	57.466	Gadus_morhua
ENSG00000090097	PCBP4	94	86.709	ENSGALG00000027695	PCBP4	98	76.658	Gallus_gallus
ENSG00000090097	PCBP4	97	74.233	ENSGAFG00000021090	-	78	59.733	Gambusia_affinis
ENSG00000090097	PCBP4	84	71.186	ENSGAFG00000018301	pcbp4	63	77.483	Gambusia_affinis
ENSG00000090097	PCBP4	98	74.390	ENSGACG00000002664	-	97	60.192	Gasterosteus_aculeatus
ENSG00000090097	PCBP4	100	93.151	ENSGAGG00000022116	PCBP4	97	79.087	Gopherus_agassizii
ENSG00000090097	PCBP4	100	100.000	ENSGGOG00000012474	PCBP4	100	99.752	Gorilla_gorilla
ENSG00000090097	PCBP4	92	79.870	ENSHBUG00000009472	pcbp4	93	56.376	Haplochromis_burtoni
ENSG00000090097	PCBP4	97	75.000	ENSHBUG00000005329	-	96	57.623	Haplochromis_burtoni
ENSG00000090097	PCBP4	100	98.214	ENSHGLG00000012018	PCBP4	100	97.767	Heterocephalus_glaber_female
ENSG00000090097	PCBP4	100	95.567	ENSHGLG00100008748	PCBP4	100	95.567	Heterocephalus_glaber_male
ENSG00000090097	PCBP4	98	75.000	ENSHCOG00000010838	-	100	54.637	Hippocampus_comes
ENSG00000090097	PCBP4	97	74.847	ENSIPUG00000008212	pcbp4	96	61.412	Ictalurus_punctatus
ENSG00000090097	PCBP4	100	98.810	ENSSTOG00000002573	PCBP4	100	96.278	Ictidomys_tridecemlineatus
ENSG00000090097	PCBP4	100	98.810	ENSJJAG00000016235	Pcbp4	100	98.263	Jaculus_jaculus
ENSG00000090097	PCBP4	95	77.778	ENSKMAG00000014252	pcbp4	97	59.780	Kryptolebias_marmoratus
ENSG00000090097	PCBP4	97	74.233	ENSKMAG00000017554	-	97	59.416	Kryptolebias_marmoratus
ENSG00000090097	PCBP4	97	75.000	ENSLBEG00000011345	-	96	57.848	Labrus_bergylta
ENSG00000090097	PCBP4	97	78.528	ENSLACG00000015899	PCBP4	95	75.598	Latimeria_chalumnae
ENSG00000090097	PCBP4	97	74.847	ENSLOCG00000013402	pcbp4	96	58.824	Lepisosteus_oculatus
ENSG00000090097	PCBP4	96	97.765	ENSLAFG00000010732	PCBP4	100	97.765	Loxodonta_africana
ENSG00000090097	PCBP4	100	100.000	ENSMFAG00000001431	PCBP4	100	99.504	Macaca_fascicularis
ENSG00000090097	PCBP4	100	100.000	ENSMMUG00000022205	PCBP4	100	99.504	Macaca_mulatta
ENSG00000090097	PCBP4	100	100.000	ENSMNEG00000028553	PCBP4	100	99.504	Macaca_nemestrina
ENSG00000090097	PCBP4	100	100.000	ENSMLEG00000027083	PCBP4	100	99.504	Mandrillus_leucophaeus
ENSG00000090097	PCBP4	92	79.221	ENSMAMG00000010163	pcbp4	93	56.823	Mastacembelus_armatus
ENSG00000090097	PCBP4	95	79.167	ENSMAMG00000011364	-	95	58.124	Mastacembelus_armatus
ENSG00000090097	PCBP4	97	75.000	ENSMZEG00005023631	-	96	57.623	Maylandia_zebra
ENSG00000090097	PCBP4	92	79.870	ENSMZEG00005008852	pcbp4	93	56.376	Maylandia_zebra
ENSG00000090097	PCBP4	68	66.667	ENSMGAG00000003895	-	99	65.686	Meleagris_gallopavo
ENSG00000090097	PCBP4	94	86.709	ENSMGAG00000005091	-	96	84.360	Meleagris_gallopavo
ENSG00000090097	PCBP4	100	98.214	ENSMAUG00000021064	Pcbp4	100	96.774	Mesocricetus_auratus
ENSG00000090097	PCBP4	100	99.405	ENSMICG00000002686	PCBP4	100	98.759	Microcebus_murinus
ENSG00000090097	PCBP4	100	98.214	ENSMOCG00000013557	Pcbp4	100	97.270	Microtus_ochrogaster
ENSG00000090097	PCBP4	89	66.667	ENSMMOG00000017756	pcbp4	98	54.902	Mola_mola
ENSG00000090097	PCBP4	97	64.417	ENSMMOG00000020533	-	98	54.036	Mola_mola
ENSG00000090097	PCBP4	100	95.946	ENSMODG00000011790	PCBP4	85	90.488	Monodelphis_domestica
ENSG00000090097	PCBP4	92	78.571	ENSMALG00000020318	pcbp4	84	63.325	Monopterus_albus
ENSG00000090097	PCBP4	98	74.468	ENSMALG00000022117	-	99	54.798	Monopterus_albus
ENSG00000090097	PCBP4	100	97.619	MGP_CAROLIEiJ_G0032623	Pcbp4	100	98.214	Mus_caroli
ENSG00000090097	PCBP4	100	97.619	ENSMUSG00000023495	Pcbp4	100	98.214	Mus_musculus
ENSG00000090097	PCBP4	100	98.214	MGP_PahariEiJ_G0015491	Pcbp4	100	98.477	Mus_pahari
ENSG00000090097	PCBP4	100	97.619	MGP_SPRETEiJ_G0033768	-	100	98.214	Mus_spretus
ENSG00000090097	PCBP4	100	99.405	ENSMPUG00000011766	PCBP4	100	98.263	Mustela_putorius_furo
ENSG00000090097	PCBP4	100	97.619	ENSNGAG00000013148	Pcbp4	100	97.519	Nannospalax_galili
ENSG00000090097	PCBP4	97	63.804	ENSNBRG00000015885	-	98	53.812	Neolamprologus_brichardi
ENSG00000090097	PCBP4	88	57.047	ENSNBRG00000007475	pcbp4	98	48.758	Neolamprologus_brichardi
ENSG00000090097	PCBP4	100	100.000	ENSNLEG00000007064	PCBP4	100	99.504	Nomascus_leucogenys
ENSG00000090097	PCBP4	95	89.888	ENSMEUG00000006917	PCBP4	95	89.888	Notamacropus_eugenii
ENSG00000090097	PCBP4	95	100.000	ENSOPRG00000008763	PCBP4	98	100.000	Ochotona_princeps
ENSG00000090097	PCBP4	100	97.802	ENSODEG00000018230	PCBP4	100	97.270	Octodon_degus
ENSG00000090097	PCBP4	100	94.595	ENSOANG00000014110	PCBP4	97	87.531	Ornithorhynchus_anatinus
ENSG00000090097	PCBP4	100	99.405	ENSOCUG00000025336	PCBP4	100	98.015	Oryctolagus_cuniculus
ENSG00000090097	PCBP4	97	66.258	ENSORLG00000009899	-	98	53.556	Oryzias_latipes
ENSG00000090097	PCBP4	95	76.389	ENSORLG00000003061	pcbp4	94	53.030	Oryzias_latipes
ENSG00000090097	PCBP4	97	75.000	ENSORLG00020001183	-	96	57.399	Oryzias_latipes_hni
ENSG00000090097	PCBP4	95	76.389	ENSORLG00015019262	pcbp4	94	53.219	Oryzias_latipes_hsok
ENSG00000090097	PCBP4	97	75.000	ENSORLG00015017819	-	96	57.175	Oryzias_latipes_hsok
ENSG00000090097	PCBP4	97	75.000	ENSOMEG00000011545	-	96	57.399	Oryzias_melastigma
ENSG00000090097	PCBP4	98	74.026	ENSOMEG00000003516	-	93	56.120	Oryzias_melastigma
ENSG00000090097	PCBP4	100	99.405	ENSOGAG00000032384	PCBP4	100	99.007	Otolemur_garnettii
ENSG00000090097	PCBP4	96	97.541	ENSOARG00000006603	PCBP4	100	97.541	Ovis_aries
ENSG00000090097	PCBP4	100	100.000	ENSPPAG00000038764	PCBP4	100	99.752	Pan_paniscus
ENSG00000090097	PCBP4	100	99.405	ENSPPRG00000006165	PCBP4	100	98.263	Panthera_pardus
ENSG00000090097	PCBP4	99	99.398	ENSPTIG00000005401	PCBP4	95	98.254	Panthera_tigris_altaica
ENSG00000090097	PCBP4	100	100.000	ENSPTRG00000014983	PCBP4	100	100.000	Pan_troglodytes
ENSG00000090097	PCBP4	100	100.000	ENSPANG00000026222	PCBP4	100	99.504	Papio_anubis
ENSG00000090097	PCBP4	93	74.522	ENSPKIG00000005487	-	96	59.122	Paramormyrops_kingsleyae
ENSG00000090097	PCBP4	92	76.623	ENSPKIG00000010244	pcbp4	100	53.899	Paramormyrops_kingsleyae
ENSG00000090097	PCBP4	100	84.524	ENSPSIG00000011286	PCBP4	97	71.920	Pelodiscus_sinensis
ENSG00000090097	PCBP4	96	82.051	ENSPMGG00000000063	pcbp4	99	54.306	Periophthalmus_magnuspinnatus
ENSG00000090097	PCBP4	90	65.132	ENSPMGG00000022732	-	98	54.503	Periophthalmus_magnuspinnatus
ENSG00000090097	PCBP4	100	98.214	ENSPEMG00000009276	Pcbp4	100	97.519	Peromyscus_maniculatus_bairdii
ENSG00000090097	PCBP4	100	95.946	ENSPCIG00000018151	PCBP4	96	90.732	Phascolarctos_cinereus
ENSG00000090097	PCBP4	97	74.233	ENSPFOG00000002989	-	96	57.399	Poecilia_formosa
ENSG00000090097	PCBP4	86	75.000	ENSPFOG00000014474	pcbp4	98	59.639	Poecilia_formosa
ENSG00000090097	PCBP4	98	52.727	ENSPLAG00000011438	-	98	46.824	Poecilia_latipinna
ENSG00000090097	PCBP4	79	52.507	ENSPLAG00000023316	pcbp4	89	51.715	Poecilia_latipinna
ENSG00000090097	PCBP4	81	41.216	ENSPMEG00000012990	pcbp4	100	39.465	Poecilia_mexicana
ENSG00000090097	PCBP4	97	61.350	ENSPREG00000017370	-	98	50.783	Poecilia_reticulata
ENSG00000090097	PCBP4	89	58.462	ENSPREG00000021498	-	80	58.462	Poecilia_reticulata
ENSG00000090097	PCBP4	100	100.000	ENSPPYG00000013822	PCBP4	100	99.752	Pongo_abelii
ENSG00000090097	PCBP4	95	90.625	ENSPCAG00000009515	PCBP4	97	90.625	Procavia_capensis
ENSG00000090097	PCBP4	100	99.405	ENSPCOG00000027535	PCBP4	100	98.263	Propithecus_coquereli
ENSG00000090097	PCBP4	95	91.111	ENSPVAG00000012474	PCBP4	97	96.429	Pteropus_vampyrus
ENSG00000090097	PCBP4	83	70.629	ENSPNYG00000019234	pcbp4	100	52.027	Pundamilia_nyererei
ENSG00000090097	PCBP4	97	63.804	ENSPNYG00000003098	-	98	53.587	Pundamilia_nyererei
ENSG00000090097	PCBP4	97	75.460	ENSPNAG00000025434	pcbp4	96	57.269	Pygocentrus_nattereri
ENSG00000090097	PCBP4	100	98.214	ENSRNOG00000012406	Pcbp4	100	97.767	Rattus_norvegicus
ENSG00000090097	PCBP4	100	100.000	ENSRBIG00000043793	PCBP4	100	99.504	Rhinopithecus_bieti
ENSG00000090097	PCBP4	100	100.000	ENSRROG00000034589	PCBP4	100	99.504	Rhinopithecus_roxellana
ENSG00000090097	PCBP4	100	100.000	ENSSBOG00000027029	PCBP4	100	99.504	Saimiri_boliviensis_boliviensis
ENSG00000090097	PCBP4	90	94.483	ENSSHAG00000007362	PCBP4	100	91.416	Sarcophilus_harrisii
ENSG00000090097	PCBP4	95	74.667	ENSSFOG00015012075	PCBP4	99	59.397	Scleropages_formosus
ENSG00000090097	PCBP4	70	56.863	ENSSFOG00015008221	pcbp4	63	53.517	Scleropages_formosus
ENSG00000090097	PCBP4	92	79.870	ENSSMAG00000005827	pcbp4	90	57.254	Scophthalmus_maximus
ENSG00000090097	PCBP4	97	74.233	ENSSMAG00000009392	-	95	56.726	Scophthalmus_maximus
ENSG00000090097	PCBP4	97	63.804	ENSSDUG00000015540	-	98	53.812	Seriola_dumerili
ENSG00000090097	PCBP4	86	70.732	ENSSDUG00000017719	pcbp4	97	53.477	Seriola_dumerili
ENSG00000090097	PCBP4	89	78.689	ENSSLDG00000024847	-	75	75.000	Seriola_lalandi_dorsalis
ENSG00000090097	PCBP4	97	63.804	ENSSLDG00000007851	-	98	53.812	Seriola_lalandi_dorsalis
ENSG00000090097	PCBP4	99	86.301	ENSSPUG00000000194	PCBP4	100	73.317	Sphenodon_punctatus
ENSG00000090097	PCBP4	98	75.000	ENSSPAG00000003033	-	96	57.848	Stegastes_partitus
ENSG00000090097	PCBP4	84	71.429	ENSSPAG00000019058	-	92	48.930	Stegastes_partitus
ENSG00000090097	PCBP4	100	99.405	ENSSSCG00000028446	PCBP4	100	98.263	Sus_scrofa
ENSG00000090097	PCBP4	93	88.750	ENSTGUG00000006393	PCBP4	99	83.436	Taeniopygia_guttata
ENSG00000090097	PCBP4	92	65.584	ENSTRUG00000007426	-	97	53.776	Takifugu_rubripes
ENSG00000090097	PCBP4	97	79.167	ENSTNIG00000017887	-	97	62.315	Tetraodon_nigroviridis
ENSG00000090097	PCBP4	95	55.398	ENSTBEG00000015770	PCBP4	100	97.727	Tupaia_belangeri
ENSG00000090097	PCBP4	76	98.235	ENSTTRG00000001443	PCBP4	83	98.235	Tursiops_truncatus
ENSG00000090097	PCBP4	95	100.000	ENSUAMG00000020871	PCBP4	98	100.000	Ursus_americanus
ENSG00000090097	PCBP4	100	98.810	ENSUMAG00000021609	PCBP4	94	97.375	Ursus_maritimus
ENSG00000090097	PCBP4	100	99.405	ENSVVUG00000026857	PCBP4	100	98.015	Vulpes_vulpes
ENSG00000090097	PCBP4	98	81.818	ENSXCOG00000000111	-	90	74.699	Xiphophorus_couchianus
ENSG00000090097	PCBP4	86	75.000	ENSXCOG00000017325	pcbp4	63	78.523	Xiphophorus_couchianus
ENSG00000090097	PCBP4	97	74.233	ENSXMAG00000024530	-	96	57.143	Xiphophorus_maculatus
ENSG00000090097	PCBP4	92	79.221	ENSXMAG00000015709	pcbp4	76	63.085	Xiphophorus_maculatus
ENSG00000090097	PCBP4	84	49.015	ENSXMAG00000022188	-	90	47.783	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003677	DNA binding	-	IEA	Function
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0003723	RNA binding	10936052.	NAS	Function
GO:0003730	mRNA 3'-UTR binding	20817677.	IDA	Function
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	-	TAS	Process
GO:0043488	regulation of mRNA stability	20817677.	IDA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.