EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
19585652	Overexpression of far upstream element binding proteins: a mechanism regulating proliferation and migration in liver cancer cells.	Hepatology	2009 Oct	Malz M	doi: 10.1002/hep.23051.
26810065	The far-upstream element-binding protein 2 is correlated with proliferation and doxorubicin resistance in human breast cancer cell lines.	Tumour Biol	2016 Jul	Wang YY	doi: 10.1007/s13277-016-4819-2
15514971	IL-1beta induces stabilization of IL-8 mRNA in malignant breast cancer cells via the 3' untranslated region: Involvement of divergent RNA-binding factors HuR, KSRP and TIAR.	Int J Cancer	2005 Mar 1	Suswam EA	-
27644194	KH-type splicing regulatory protein (KHSRP) contributes to tumorigenesis by promoting miR-26a maturation in small cell lung cancer.	Mol Cell Biochem	2016 Nov	Tong L	-

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr19	6416651	Splice_Site	novel	X443_splice	0.55
BLCA	chr19	6418048	Missense_Mutation	rs763165761	R304Q	0.19
BLCA	chr19	6418745	Missense_Mutation	novel	G246V	0.15
BLCA	chr19	6418737	Missense_Mutation	novel	I249F	0.13
BRCA	chr19	6422371	Missense_Mutation	NA	F105L	0.24
BRCA	chr19	6415886	Frame_Shift_Ins	NA	*P537Afs25**	0.69
BRCA	chr19	6415302	Splice_Site	novel	X656_splice	0.63
BRCA	chr19	6416400	Missense_Mutation	NA	L499P	0.63
CESC	chr19	6413926	3'UTR	novel		0.27
CESC	chr19	6418789	Silent	novel	Q231Q	0.12
CESC	chr19	6413636	3'UTR	novel		0.44
CESC	chr19	6414019	3'UTR	novel		0.3
CESC	chr19	6411862	3'Flank	novel		0.09
CESC	chr19	6415411	Silent	novel	T645T	0.49
COAD	chr19	6421648	Splice_Site	NA	X129_splice	0.3
COAD	chr19	6416842	Missense_Mutation	NA	P408R	0.18
COAD	chr19	6416493	Silent	rs769685889	I495I	0.22
COAD	chr19	6422411	Missense_Mutation	novel	A92V	0.17
COAD	chr19	6415173	Frame_Shift_Del	NA	*Q699Sfs24**	0.35
COAD	chr19	6417815	Silent	rs555066011	G335G	0.22
COAD	chr19	6416784	Missense_Mutation	novel	M427I	0.35
COAD	chr19	6418822	Frame_Shift_Ins	novel	*G221Rfs37**	0.43
COAD	chr19	6416842	Missense_Mutation	rs758290639	P408L	0.34
COAD	chr19	6416545	Missense_Mutation	novel	R478L	0.08
COAD	chr19	6418043	Missense_Mutation	NA	R306C	0.25
COAD	chr19	6417815	Silent	rs555066011	G335G	0.28
COAD	chr19	6416519	Missense_Mutation	novel	A487T	0.24
COAD	chr19	6418842	Missense_Mutation	NA	R214W	0.53
COAD	chr19	6415241	Missense_Mutation	NA	A676V	0.28
COAD	chr19	6415280	Frame_Shift_Del	novel	*G663Vfs60**	0.14
ESCA	chr19	6411855	3'Flank	novel		0.33
ESCA	chr19	6413500	3'UTR	novel		0.39
GBM	chr19	6420472	Splice_Site	NA	X142_splice	0.24
GBM	chr19	6418531	Silent	rs201647817	T277T	0.45
GBM	chr19	6416408	Splice_Site	NA	X497_splice	0.14
GBM	chr19	6418502	Missense_Mutation	NA	G287E	0.19
HNSC	chr19	6416872	Missense_Mutation	novel	P398R	0.27
HNSC	chr19	6416868	Silent	novel	G399G	0.19
HNSC	chr19	6422357	Missense_Mutation	novel	R110K	0.15
LGG	chr19	6416884	Splice_Site	NA	X395_splice	0.29
LIHC	chr19	6416506	Missense_Mutation	NA	I491T	0.41
LIHC	chr19	6420125	Silent	NA	E165E	0.38
LIHC	chr19	6416819	Missense_Mutation	rs764189159	G416S	0.4
LUAD	chr19	6422360	Missense_Mutation	rs201259560	K109R	0.22
LUAD	chr19	6420429	Silent	NA	V156V	0.52
LUAD	chr19	6416543	Missense_Mutation	novel	G479R	0.5
LUAD	chr19	6415169	Missense_Mutation	rs779255957	P700L	0.18
LUAD	chr19	6418048	Missense_Mutation	NA	R304L	0.37
LUAD	chr19	6422404	Silent	rs539731278	T94T	0.2
LUAD	chr19	6417793	Missense_Mutation	novel	E343Q	0.21
LUAD	chr19	6414086	3'UTR	novel		0.27
LUAD	chr19	6418500	Missense_Mutation	NA	D288H	0.11
LUSC	chr19	6416614	Missense_Mutation	novel	G455E	0.12
LUSC	chr19	6418720	Missense_Mutation	rs577750058	E254D	0.19
LUSC	chr19	6422359	Missense_Mutation	NA	K109N	0.18
LUSC	chr19	6418702	Missense_Mutation	novel	Q260H	0.4
LUSC	chr19	6417021	Missense_Mutation	novel	A383G	0.13
LUSC	chr19	6420423	Splice_Region	NA	L158L	0.26
LUSC	chr19	6418809	Missense_Mutation	novel	D225Y	0.52
LUSC	chr19	6418049	Missense_Mutation	novel	R304W	0.21
LUSC	chr19	6416832	Silent	novel	R411R	0.53
LUSC	chr19	6417811	Frame_Shift_Del	novel	*V337Sfs8**	0.14
OV	chr19	6417069	Frame_Shift_Ins	novel	*E367Afs119**	0.05
OV	chr19	6414092	3'UTR	novel		0.53
PAAD	chr19	6417807	Missense_Mutation	novel	I338T	0.07
PRAD	chr19	6415301	Missense_Mutation	rs765792194	A656V	0.28
READ	chr19	6416305	Missense_Mutation	NA	P531S	0.23
READ	chr19	6418018	Missense_Mutation	novel	R314Q	0.35
SARC	chr19	6416537	Missense_Mutation	novel	P481S	0.24
SARC	chr19	6422341	Splice_Region	novel	G115G	0.53
SARC	chr19	6418750	Frame_Shift_Ins	novel	*A245Gfs13**	0.5
SKCM	chr19	6418813	Silent	rs747615967	F223F	0.42
SKCM	chr19	6418582	Splice_Site	novel	X261_splice	0.28
SKCM	chr19	6421683	Missense_Mutation	NA	P118S	0.23
SKCM	chr19	6418729	Silent	NA	K251K	0.11
SKCM	chr19	6418791	Nonsense_Mutation	NA	Q231*	0.5
STAD	chr19	6415384	Silent	novel	K654K	0.27
STAD	chr19	6417044	Silent	NA	P375P	0.1
STAD	chr19	6416493	Silent	rs769685889	I495I	0.5
STAD	chr19	6417757	Missense_Mutation	novel	R355W	0.52
STAD	chr19	6418511	Missense_Mutation	NA	R284H	0.11
STAD	chr19	6422383	Silent	novel	P101P	0.18
UCEC	chr19	6414108	3'UTR	rs373531467		0.38
UCEC	chr19	6416493	Silent	rs769685889	I495I	0.37
UCEC	chr19	6422415	Missense_Mutation	NA	D91N	0.31
UCEC	chr19	6411883	3'Flank	novel		0.38
UCEC	chr19	6417815	Silent	rs555066011	G335G	0.14
UCEC	chr19	6418002	Silent	NA	S319S	0.38
UCEC	chr19	6416843	Missense_Mutation	rs779852581	P408S	0.42
UCEC	chr19	6416836	Frame_Shift_Del	novel	*G410Afs18**	0.26
UCEC	chr19	6422404	Silent	rs539731278	T94T	0.39
UCEC	chr19	6413383	3'UTR	novel		0.76
UCEC	chr19	6418030	Missense_Mutation	novel	G310D	0.35
UCEC	chr19	6415139	Splice_Site	novel	X709_splice	0.22
UCEC	chr19	6411742	3'Flank	rs769401547		0.37
UCEC	chr19	6416493	Silent	rs769685889	I495I	0.31
UCEC	chr19	6417026	Silent	rs372826447	H381H	0.15
UCEC	chr19	6418546	Silent	NA	D272D	0.1
UCEC	chr19	6419240	Missense_Mutation	novel	R190C	0.22
UCEC	chr19	6417788	Missense_Mutation	novel	M344I	0.15
UCEC	chr19	6419256	Silent	rs199705336	S184S	0.43
UCEC	chr19	6419256	Silent	rs199705336	S184S	0.53
UCEC	chr19	6417060	Missense_Mutation	novel	A370D	0.37
UCEC	chr19	6418001	Missense_Mutation	NA	R320W	0.12
UCEC	chr19	6416754	Silent	novel	G437G	0.48
UCEC	chr19	6416850	Silent	novel	G405G	0.21
UCEC	chr19	6411748	3'Flank	rs568655061		0.25
UCEC	chr19	6413345	3'Flank	rs576374342		0.38
UCEC	chr19	6416741	Nonsense_Mutation	novel	R442*	0.4
UCEC	chr19	6417076	Missense_Mutation	NA	G365W	0.26
UCEC	chr19	6416330	Silent	novel	P522P	0.28
UCEC	chr19	6415535	Splice_Region	rs747810170	I629I	0.48
UCEC	chr19	6412320	3'Flank	novel		0.54
UCEC	chr19	6413392	3'UTR	novel		0.35
UCEC	chr19	6416606	Missense_Mutation	novel	V458I	0.41
UCEC	chr19	6420107	Silent	novel	Q171Q	0.4
UCEC	chr19	6417757	Missense_Mutation	novel	R355W	0.31
UCEC	chr19	6422416	Silent	rs755058483	G90G	0.34
UCEC	chr19	6417815	Silent	rs555066011	G335G	0.51
UCEC	chr19	6414004	3'UTR	novel		0.26
UCEC	chr19	6418532	Missense_Mutation	rs765261230	T277M	0.44
UCEC	chr19	6416793	Silent	rs374401627	G424G	0.35
UCEC	chr19	6417042	Frame_Shift_Del	novel	*P376Qfs52**	0.49
UCEC	chr19	6418823	Frame_Shift_Del	novel	*P220Qfs20**	0.11
UCEC	chr19	6416546	Missense_Mutation	novel	R478W	0.42
UCEC	chr19	6422373	Missense_Mutation	novel	F105V	0.03
UCEC	chr19	6420472	Splice_Site	NA	X142_splice	0.5
UCEC	chr19	6416617	Missense_Mutation	NA	T454M	0.58
UCEC	chr19	6415300	Splice_Region	rs764013651	A656A	0.42
UCEC	chr19	6419205	Splice_Region	novel	V201V	0.29
UCS	chr19	6417005	Silent	rs554880290	D388D	0.07
UCS	chr19	6416493	Silent	rs769685889	I495I	0.36

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	DEL	0.2059	0.11788
CHOL	DEL	0.0833	0.067545
LAML	DEL	0.0105	0.24147
LIHC	DEL	0.1811	0.12467
PAAD	DEL	0.1304	0.0060878
PCPG	DEL	0	0.13351
READ	DEL	0.103	0.23023
THCA	DEL	0.012	0.24038
THYM	DEL	0.0244	0.022012
UCEC	DEL	0.2338	0.027215
UCS	DEL	0.6429	0.089783

Survival Analysis

Cancer	P-value	Q-value
STAD	0.0094	Kaplan-Meier Survival Analysis
MESO	0.0074	Kaplan-Meier Survival Analysis
ACC	0.0001	Kaplan-Meier Survival Analysis
HNSC	0.045	Kaplan-Meier Survival Analysis
SKCM	0.004	Kaplan-Meier Survival Analysis
PRAD	0.023	Kaplan-Meier Survival Analysis
KIRP	0.00033	Kaplan-Meier Survival Analysis
GBM	0.036	Kaplan-Meier Survival Analysis
LIHC	0.023	Kaplan-Meier Survival Analysis
UVM	0.027	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

PRI

Literatures

Expression

Transcripts

Gene Model

PPI

Paralog

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000088247 (Gene tree)
Gene ID: 8570
Gene Symbol: KHSRP
Alias: KSRP|FBP2|FUBP2
Full Name: KH-type splicing regulatory protein
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Minus strand
Length: 11,708 bases
Position: chr19:6,413,104-6,424,811
Accession: 6316
Summary: The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997 [PubMed 9136930]; Gherzi et al., 2004 [PubMed 15175153]).[supplied by OMIM, Apr 2010]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000381216	KH_1	PF00013.29	1.7e-64	1	4
ENSP00000381216	KH_1	PF00013.29	1.7e-64	2	4
ENSP00000381216	KH_1	PF00013.29	1.7e-64	3	4
ENSP00000381216	KH_1	PF00013.29	1.7e-64	4	4
ENSP00000478033	KH_1	PF00013.29	1.7e-64	1	4
ENSP00000478033	KH_1	PF00013.29	1.7e-64	2	4
ENSP00000478033	KH_1	PF00013.29	1.7e-64	3	4
ENSP00000478033	KH_1	PF00013.29	1.7e-64	4	4
ENSP00000469830	KH_1	PF00013.29	4.7e-36	1	2
ENSP00000469830	KH_1	PF00013.29	4.7e-36	2	2
ENSP00000471262	KH_1	PF00013.29	1.9e-28	1	2
ENSP00000471262	KH_1	PF00013.29	1.9e-28	2	2
ENSP00000469431	KH_1	PF00013.29	1.5e-26	1	2
ENSP00000469431	KH_1	PF00013.29	1.5e-26	2	2
ENSP00000473254	KH_1	PF00013.29	1.4e-15	1	1
ENSP00000381216	KH_2	PF07650.17	3e-18	1	1
ENSP00000478033	KH_2	PF07650.17	3e-18	1	1
ENSP00000469830	KH_2	PF07650.17	4.7e-10	1	1
ENSP00000471262	KH_2	PF07650.17	7e-09	1	1
ENSP00000471146	DUF1897	PF09005.10	2.2e-13	1	2
ENSP00000471146	DUF1897	PF09005.10	2.2e-13	2	2
ENSP00000381216	DUF1897	PF09005.10	2e-12	1	2
ENSP00000381216	DUF1897	PF09005.10	2e-12	2	2
ENSP00000472328	DUF1897	PF09005.10	1.6e-09	1	1
ENSP00000472347	DUF1897	PF09005.10	2e-09	1	1
ENSP00000469804	DUF1897	PF09005.10	6e-09	1	1
ENSP00000473254	DUF1897	PF09005.10	5.1e-08	1	1
ENSP00000478033	DUF1897	PF09005.10	3.2e-06	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	polyT & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	PolyT & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

RNA-binding sites

Click here to download all RNA binding sites

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
28847731	KSRP suppresses cell invasion and metastasis through miR-23a-mediated EGR3 mRNA degradation in non-small cell lung cancer.	Biochim Biophys Acta Gene Regul Mech	2017 Oct	Chien MH	doi: 10.1016/j.bbagrm.2017.08.005
21935887	The role of KSRP in mRNA decay and microRNA precursor maturation.	Wiley Interdiscip Rev RNA	2010 Sep-Oct	Gherzi R	doi: 10.1002/wrna.2
24697202	Control of pro-angiogenic cytokine mRNA half-life in cancer: the role of AU-rich elements and associated proteins.	J Interferon Cytokine Res	2014 Apr	Griseri P	doi: 10.1089/jir.2013.0140.
27396342	miRNA-Mediated KHSRP Silencing Rewires Distinct Post-transcriptional Programs during TGF-β-Induced Epithelial-to-Mesenchymal Transition.	Cell Rep	2016 Jul 26	Puppo M	doi: 10.1016/j.celrep.2016.06.055
16950790	The polypyrimidine tract-binding protein (PTB) is involved in the post-transcriptional regulation of human inducible nitric oxide synthase expression.	J Biol Chem	2006 Oct 27	Pautz A	-
19015122	A cytoplasmic variant of the KH-type splicing regulatory protein serves as a decay-promoting factor for phosphoglycerate kinase 2 mRNA in murine male germ cells.	Nucleic Acids Res	2008 Dec	Xu M	doi: 10.1093/nar/gkn800
26545813	LEDGF/p75 interacts with mRNA splicing factors and targets HIV-1 integration to highly spliced genes.	Genes Dev	2015 Nov 1	Singh PK	doi: 10.1101/gad.267609.115.
29254151	KH-type splicing regulatory protein is involved in esophageal squamous cell carcinoma progression.	Oncotarget	2017 Sep 15	Fujita Y	doi: 10.18632/oncotarget.20926
31313286	Inhibition of KHSRP sensitizes colorectal cancer to 5-fluoruracil through miR-501-5p-mediated ERRFI1 mRNA degradation.	J Cell Physiol	2019 Jul 16	Pan R	doi: 10.1002/jcp.29076
25352548	Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity.	Nucleic Acids Res	2014 Nov 10	Bollmann F	doi: 10.1093/nar/gku1033
9136930	A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer.	Genes Dev	1997 Apr 15	Min H	-
15514971	IL-1beta induces stabilization of IL-8 mRNA in malignant breast cancer cells via the 3' untranslated region: Involvement of divergent RNA-binding factors HuR, KSRP and TIAR.	Int J Cancer	2005 Mar 1	Suswam EA	-
15175153	A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery.	Mol Cell	2004 Jun 4	Gherzi R	-
14657238	Differentiation-induced colocalization of the KH-type splicing regulatory protein with polypyrimidine tract binding protein and the c-src pre-mRNA.	Mol Biol Cell	2004 Feb	Hall MP	-
19458619	The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs.	Nature	2009 Jun 18	Trabucchi M	doi: 10.1038/nature08025
19423639	LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages.	FASEB J	2009 Sep	Ruggiero T	doi: 10.1096/fj.09-131342
17998247	KH-type splicing regulatory protein interacts with survival motor neuron protein and is misregulated in spinal muscular atrophy.	Hum Mol Genet	2008 Feb 15	Tadesse H	-
22844247	Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP.	PLoS Genet	2012	Repetto E	doi: 10.1371/journal.pgen.1002823
22847996	KSRP: a checkpoint for inflammatory cytokine production in astrocytes.	Glia	2012 Nov	Li X	doi: 10.1002/glia.22396
17177604	The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling.	PLoS Biol	2006 Dec	Gherzi R	-
21982546	RNA-binding proteins and gene regulation in myogenesis.	Trends Pharmacol Sci	2011 Nov	Apponi LH	doi: 10.1016/j.tips.2011.06.004
21917750	AU-rich RNA binding proteins in hematopoiesis and leukemogenesis.	Blood	2011 Nov 24	Baou M	doi: 10.1182/blood-2011-07-347237
21933836	The X-chromosome-linked intellectual disability protein PQBP1 is a component of neuronal RNA granules and regulates the appearance of stress granules.	Hum Mol Genet	2011 Dec 15	Kunde SA	doi: 10.1093/hmg/ddr430
21886180	PI3K/AKT signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis.	Cell Death Differ	2012 Mar	Briata P	doi: 10.1038/cdd.2011.117
21690298	Posttranscriptional control of type I interferon genes by KSRP in the innate immune response against viral infection.	Mol Cell Biol	2011 Aug	Lin WJ	doi: 10.1128/MCB.05073-11
20438856	Regulation of the expression of inducible nitric oxide synthase.	Nitric Oxide	2010 Sep 15	Pautz A	doi: 10.1016/j.niox.2010.04.007
20385598	Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets.	Nucleic Acids Res	2010 Aug	Diaz-Moreno I	doi: 10.1093/nar/gkq216
28362162	Hypoxia and Hypoglycemia synergistically regulate mRNA stability.	RNA Biol	2017 Jul 3	Carraway KR	doi: 10.1080/15476286.2017.1311456
25189382	microRNA and human inducible nitric oxide synthase.	Vitam Horm	2014	Guo Z	doi: 10.1016/B978-0-12-800254-4.00002-7.
25027559	KHSRP participates in manganese-induced neurotoxicity in rat striatum and PC12 cells.	J Mol Neurosci	2015 Feb	Shi S	doi: 10.1007/s12031-014-0367-7
24732799	KSRP and MicroRNA 145 are negative regulators of lipolysis in white adipose tissue.	Mol Cell Biol	2014 Jun	Lin YY	doi: 10.1128/MCB.00042-14
24368152	Spatiotemporal expression of KHSRP modulates Schwann cells and neuronal differentiation after sciatic nerve injury.	Int J Biochem Cell Biol	2014 Mar	Zhu X	doi: 10.1016/j.biocel.2013.12.008
28088441	Resveratrol limits epithelial to mesenchymal transition through modulation of KHSRP/hnRNPA1-dependent alternative splicing in mammary gland cells.	Biochim Biophys Acta Gene Regul Mech	2017 Mar	Moshiri A	doi: 10.1016/j.bbagrm.2017.01.001
23791529	DNA-damage-induced nuclear export of precursor microRNAs is regulated by the ATM-AKT pathway.	Cell Rep	2013 Jun 27	Wan G	doi: 10.1016/j.celrep.2013.05.038
24722250	KSRP ablation enhances brown fat gene program in white adipose tissue through reduced miR-150 expression.	Diabetes	2014 Sep	Chou CF	doi: 10.2337/db13-1901
25385579	H19 long noncoding RNA controls the mRNA decay promoting function of KSRP.	Proc Natl Acad Sci U S A	2014 Nov 25	Giovarelli M	doi: 10.1073/pnas.1415098111
27478153	The miRNA biogenesis factors, p72/DDX17 and KHSRP regulate the protein level of Ago2 in human cells.	Biochim Biophys Acta	2016 Oct	Connerty P	doi: 10.1016/j.bbagrm.2016.07.013
25992900	Roles of Prolyl Isomerases in RNA-Mediated Gene Expression.	Biomolecules	2015 May 18	Thapar R	doi: 10.3390/biom5020974.
29222050	Effects of the RNA-binding protein, KSRP, on innate immune response against Helicobacter pylori infection in mice.	Biochem Biophys Res Commun	2018 Jan 8	Li N	doi: 10.1016/j.bbrc.2017.12.016
29728998	KH-type splicing regulatory protein is regulated by nuclear factor-kB signaling to mediate innate immunity in Caco-2 cells infected by Salmonella enteritidis.	Folia Microbiol (Praha)	2018 Nov	Nie Y	doi: 10.1007/s12223-018-0606-3
30578289	The KH-type splicing regulatory protein (KSRP) regulates type III interferon expression post-transcriptionally.	Biochem J	2019 Jan 31	Schmidtke L	doi: 10.1042/BCJ20180522.
30696738	Genome-Wide Profiling of Cervical RNA-Binding Proteins Identifies Human Papillomavirus Regulation of RNASEH2A Expression by Viral E7 and E2F1.	MBio	2019 Jan 29	Xu J	doi: 10.1128/mBio.02687-18.
11003644	Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein.	Mol Cell Biol	2000 Oct	Markovtsov V	-
17531340	Proteomic analysis of gene expression following hypoxia and reoxygenation reveals proteins involved in the recovery from endoplasmic reticulum and oxidative stress.	Radiother Oncol	2007 Jun	Magagnin MG	-
19010963	Far upstream element binding protein 2 interacts with enterovirus 71 internal ribosomal entry site and negatively regulates viral translation.	Nucleic Acids Res	2009 Jan	Lin JY	doi: 10.1093/nar/gkn901
26708421	Diverse roles of the nucleic acid-binding protein KHSRP in cell differentiation and disease.	Wiley Interdiscip Rev RNA	2016 Mar-Apr	Briata P	doi: 10.1002/wrna.1327

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000595258	KHSRP-206	672	-	ENSP00000469431	116 (aa)	-	M0QXW7
ENST00000600480	KHSRP-212	851	-	ENSP00000471146	176 (aa)	-	M0R0C6
ENST00000398148	KHSRP-201	2993	XM_005259668	ENSP00000381216	711 (aa)	XP_005259725	Q92945
ENST00000594745	KHSRP-203	379	-	ENSP00000469804	114 (aa)	-	M0QYG1
ENST00000599395	KHSRP-210	837	-	ENSP00000471262	279 (aa)	-	M0R0I5
ENST00000595223	KHSRP-205	956	-	ENSP00000473254	269 (aa)	-	M0R3J3
ENST00000595112	KHSRP-204	745	-	-	- (aa)	-	-
ENST00000597704	KHSRP-209	706	-	-	- (aa)	-	-
ENST00000599642	KHSRP-211	428	-	-	- (aa)	-	-
ENST00000595548	KHSRP-207	801	-	ENSP00000469830	169 (aa)	-	M0QYH3
ENST00000594496	KHSRP-202	999	-	ENSP00000472347	143 (aa)	-	M0R263
ENST00000619396	KHSRP-213	2226	-	ENSP00000478033	711 (aa)	-	A0A087WTP3
ENST00000597656	KHSRP-208	328	-	ENSP00000472328	79 (aa)	-	M0R251

Gene Model

Click here to download 's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000088247's network

Paralog

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000088247	KHSRP	99	35.938	ENSG00000183570	PCBP3	96	30.189
ENSG00000088247	KHSRP	100	73.276	ENSG00000162613	FUBP1	93	60.781
ENSG00000088247	KHSRP	99	34.247	ENSG00000197111	PCBP2	74	33.333
ENSG00000088247	KHSRP	99	35.616	ENSG00000090097	PCBP4	100	30.303
ENSG00000088247	KHSRP	96	31.507	ENSG00000139910	NOVA1	64	41.667
ENSG00000088247	KHSRP	63	30.137	ENSG00000165119	HNRNPK	66	30.303
ENSG00000088247	KHSRP	99	62.275	ENSG00000107164	FUBP3	95	45.274
ENSG00000088247	KHSRP	95	31.250	ENSG00000136231	IGF2BP3	52	31.250
ENSG00000088247	KHSRP	99	34.722	ENSG00000169564	PCBP1	64	34.667

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000088247	KHSRP	100	77.515	ENSAPOG00000009524	khsrp	96	71.478	Acanthochromis_polyacanthus
ENSG00000088247	KHSRP	99	82.738	ENSAPOG00000012989	KHSRP	93	73.552	Acanthochromis_polyacanthus
ENSG00000088247	KHSRP	100	100.000	ENSAMEG00000006978	KHSRP	91	94.935	Ailuropoda_melanoleuca
ENSG00000088247	KHSRP	100	72.781	ENSACIG00000009298	khsrp	94	67.633	Amphilophus_citrinellus
ENSG00000088247	KHSRP	99	83.333	ENSAOCG00000010189	KHSRP	93	73.865	Amphiprion_ocellaris
ENSG00000088247	KHSRP	100	78.107	ENSAOCG00000010049	khsrp	95	68.536	Amphiprion_ocellaris
ENSG00000088247	KHSRP	100	78.107	ENSAPEG00000013411	khsrp	95	68.536	Amphiprion_percula
ENSG00000088247	KHSRP	99	83.333	ENSAPEG00000008575	KHSRP	93	73.865	Amphiprion_percula
ENSG00000088247	KHSRP	100	77.515	ENSATEG00000024744	KHSRP	91	66.928	Anabas_testudineus
ENSG00000088247	KHSRP	100	75.740	ENSATEG00000019332	khsrp	95	67.500	Anabas_testudineus
ENSG00000088247	KHSRP	100	97.041	ENSACAG00000015398	KHSRP	89	92.160	Anolis_carolinensis
ENSG00000088247	KHSRP	100	100.000	ENSANAG00000027617	KHSRP	96	94.595	Aotus_nancymaae
ENSG00000088247	KHSRP	100	73.276	ENSANAG00000004931	-	93	61.153	Aotus_nancymaae
ENSG00000088247	KHSRP	99	79.882	ENSACLG00000001424	KHSRP	87	71.542	Astatotilapia_calliptera
ENSG00000088247	KHSRP	100	72.781	ENSACLG00000020487	khsrp	95	64.961	Astatotilapia_calliptera
ENSG00000088247	KHSRP	100	81.897	ENSAMXG00000036582	khsrp	93	71.270	Astyanax_mexicanus
ENSG00000088247	KHSRP	100	100.000	ENSBTAG00000021018	KHSRP	100	99.020	Bos_taurus
ENSG00000088247	KHSRP	100	73.276	ENSBTAG00000008926	FUBP1	93	62.928	Bos_taurus
ENSG00000088247	KHSRP	100	100.000	ENSCJAG00000016627	KHSRP	100	100.000	Callithrix_jacchus
ENSG00000088247	KHSRP	100	100.000	ENSCAFG00000018667	KHSRP	94	99.470	Canis_familiaris
ENSG00000088247	KHSRP	100	100.000	ENSCAFG00020019133	KHSRP	100	94.890	Canis_lupus_dingo
ENSG00000088247	KHSRP	100	73.276	ENSCAFG00020015251	-	93	62.986	Canis_lupus_dingo
ENSG00000088247	KHSRP	100	100.000	ENSCHIG00000027053	KHSRP	100	99.020	Capra_hircus
ENSG00000088247	KHSRP	100	73.276	ENSCHIG00000013418	-	93	62.830	Capra_hircus
ENSG00000088247	KHSRP	100	100.000	ENSTSYG00000011552	KHSRP	88	99.841	Carlito_syrichta
ENSG00000088247	KHSRP	100	100.000	ENSCAPG00000005534	KHSRP	84	90.020	Cavia_aperea
ENSG00000088247	KHSRP	100	100.000	ENSCPOG00000005140	KHSRP	83	89.100	Cavia_porcellus
ENSG00000088247	KHSRP	100	99.408	ENSCCAG00000025297	KHSRP	100	95.910	Cebus_capucinus
ENSG00000088247	KHSRP	100	100.000	ENSCATG00000036458	KHSRP	92	99.828	Cercocebus_atys
ENSG00000088247	KHSRP	100	100.000	ENSCLAG00000007309	KHSRP	83	90.939	Chinchilla_lanigera
ENSG00000088247	KHSRP	100	100.000	ENSCSAG00000009626	KHSRP	95	100.000	Chlorocebus_sabaeus
ENSG00000088247	KHSRP	100	72.414	ENSCPBG00000016987	-	93	61.120	Chrysemys_picta_bellii
ENSG00000088247	KHSRP	100	98.225	ENSCPBG00000005286	KHSRP	89	93.920	Chrysemys_picta_bellii
ENSG00000088247	KHSRP	100	73.276	ENSCANG00000034534	-	93	61.305	Colobus_angolensis_palliatus
ENSG00000088247	KHSRP	100	100.000	ENSCANG00000015665	KHSRP	100	94.006	Colobus_angolensis_palliatus
ENSG00000088247	KHSRP	100	100.000	ENSCGRG00001011031	Khsrp	99	98.594	Cricetulus_griseus_chok1gshd
ENSG00000088247	KHSRP	100	100.000	ENSCGRG00000015331	Khsrp	84	94.301	Cricetulus_griseus_crigri
ENSG00000088247	KHSRP	100	73.964	ENSCSEG00000011429	khsrp	95	63.054	Cynoglossus_semilaevis
ENSG00000088247	KHSRP	100	73.837	ENSCVAG00000001873	khsrp	95	65.367	Cyprinodon_variegatus
ENSG00000088247	KHSRP	100	82.759	ENSDARG00000026489	khsrp	94	68.495	Danio_rerio
ENSG00000088247	KHSRP	100	100.000	ENSDNOG00000046507	KHSRP	81	98.856	Dasypus_novemcinctus
ENSG00000088247	KHSRP	100	73.276	ENSDNOG00000013200	-	94	62.481	Dasypus_novemcinctus
ENSG00000088247	KHSRP	100	100.000	ENSDORG00000002447	Khsrp	86	84.586	Dipodomys_ordii
ENSG00000088247	KHSRP	99	98.611	ENSETEG00000004793	KHSRP	94	88.387	Echinops_telfairi
ENSG00000088247	KHSRP	100	73.276	ENSEASG00005016990	-	93	62.830	Equus_asinus_asinus
ENSG00000088247	KHSRP	100	100.000	ENSEASG00005023114	KHSRP	100	99.160	Equus_asinus_asinus
ENSG00000088247	KHSRP	100	100.000	ENSECAG00000018305	KHSRP	100	99.160	Equus_caballus
ENSG00000088247	KHSRP	100	73.276	ENSECAG00000010867	FUBP1	93	62.986	Equus_caballus
ENSG00000088247	KHSRP	100	82.840	ENSELUG00000016310	khsrp	95	68.950	Esox_lucius
ENSG00000088247	KHSRP	99	83.478	ENSELUG00000008445	-	93	65.749	Esox_lucius
ENSG00000088247	KHSRP	100	73.276	ENSFCAG00000010330	-	93	63.084	Felis_catus
ENSG00000088247	KHSRP	100	100.000	ENSFCAG00000003731	KHSRP	100	99.160	Felis_catus
ENSG00000088247	KHSRP	99	96.610	ENSFDAG00000010889	KHSRP	98	67.407	Fukomys_damarensis
ENSG00000088247	KHSRP	100	72.189	ENSFHEG00000009577	khsrp	95	63.551	Fundulus_heteroclitus
ENSG00000088247	KHSRP	100	76.923	ENSGMOG00000002166	khsrp	87	69.371	Gadus_morhua
ENSG00000088247	KHSRP	100	76.923	ENSGAFG00000010469	khsrp	95	66.195	Gambusia_affinis
ENSG00000088247	KHSRP	100	75.148	ENSGACG00000018990	khsrp	86	66.335	Gasterosteus_aculeatus
ENSG00000088247	KHSRP	99	79.167	ENSGACG00000012422	KHSRP	93	71.315	Gasterosteus_aculeatus
ENSG00000088247	KHSRP	100	98.225	ENSGAGG00000023246	KHSRP	92	93.920	Gopherus_agassizii
ENSG00000088247	KHSRP	100	72.414	ENSGAGG00000019219	-	93	61.742	Gopherus_agassizii
ENSG00000088247	KHSRP	100	73.276	ENSGGOG00000027554	FUBP1	93	61.103	Gorilla_gorilla
ENSG00000088247	KHSRP	100	100.000	ENSGGOG00000007028	KHSRP	97	100.000	Gorilla_gorilla
ENSG00000088247	KHSRP	100	73.373	ENSHBUG00000018543	khsrp	95	65.116	Haplochromis_burtoni
ENSG00000088247	KHSRP	99	79.882	ENSHBUG00000014760	KHSRP	93	71.607	Haplochromis_burtoni
ENSG00000088247	KHSRP	100	98.876	ENSHGLG00000013239	KHSRP	100	98.876	Heterocephalus_glaber_female
ENSG00000088247	KHSRP	100	98.235	ENSHGLG00100000480	KHSRP	78	67.370	Heterocephalus_glaber_male
ENSG00000088247	KHSRP	100	72.781	ENSHCOG00000020488	khsrp	94	63.994	Hippocampus_comes
ENSG00000088247	KHSRP	100	81.897	ENSIPUG00000008034	khsrp	93	73.889	Ictalurus_punctatus
ENSG00000088247	KHSRP	100	100.000	ENSSTOG00000002371	KHSRP	94	99.362	Ictidomys_tridecemlineatus
ENSG00000088247	KHSRP	100	100.000	ENSJJAG00000006370	Khsrp	95	97.324	Jaculus_jaculus
ENSG00000088247	KHSRP	100	74.556	ENSKMAG00000018579	khsrp	95	65.625	Kryptolebias_marmoratus
ENSG00000088247	KHSRP	100	78.107	ENSLBEG00000005191	khsrp	94	67.742	Labrus_bergylta
ENSG00000088247	KHSRP	100	68.047	ENSLACG00000002072	KHSRP	90	76.282	Latimeria_chalumnae
ENSG00000088247	KHSRP	100	74.138	ENSLACG00000012547	-	95	61.173	Latimeria_chalumnae
ENSG00000088247	KHSRP	99	86.957	ENSLOCG00000006229	khsrp	92	73.744	Lepisosteus_oculatus
ENSG00000088247	KHSRP	99	99.429	ENSLAFG00000002426	KHSRP	100	93.590	Loxodonta_africana
ENSG00000088247	KHSRP	100	100.000	ENSMFAG00000000292	KHSRP	100	91.139	Macaca_fascicularis
ENSG00000088247	KHSRP	100	100.000	ENSMMUG00000005597	KHSRP	100	100.000	Macaca_mulatta
ENSG00000088247	KHSRP	100	100.000	ENSMNEG00000036982	KHSRP	100	93.046	Macaca_nemestrina
ENSG00000088247	KHSRP	100	100.000	ENSMLEG00000030501	KHSRP	100	100.000	Mandrillus_leucophaeus
ENSG00000088247	KHSRP	100	73.276	ENSMLEG00000032973	-	97	59.649	Mandrillus_leucophaeus
ENSG00000088247	KHSRP	100	76.331	ENSMAMG00000011746	khsrp	92	68.852	Mastacembelus_armatus
ENSG00000088247	KHSRP	99	79.167	ENSMAMG00000023639	KHSRP	91	72.337	Mastacembelus_armatus
ENSG00000088247	KHSRP	99	79.167	ENSMZEG00005022974	-	78	72.596	Maylandia_zebra
ENSG00000088247	KHSRP	99	79.882	ENSMZEG00005011227	KHSRP	93	71.607	Maylandia_zebra
ENSG00000088247	KHSRP	100	100.000	ENSMAUG00000018966	Khsrp	87	94.719	Mesocricetus_auratus
ENSG00000088247	KHSRP	100	73.276	ENSMICG00000014463	-	91	61.601	Microcebus_murinus
ENSG00000088247	KHSRP	100	99.408	ENSMICG00000007863	KHSRP	98	96.733	Microcebus_murinus
ENSG00000088247	KHSRP	100	100.000	ENSMOCG00000018305	Khsrp	81	97.339	Microtus_ochrogaster
ENSG00000088247	KHSRP	100	68.966	ENSMMOG00000021381	-	93	61.244	Mola_mola
ENSG00000088247	KHSRP	99	69.620	ENSMMOG00000005097	-	83	66.901	Mola_mola
ENSG00000088247	KHSRP	100	98.276	ENSMODG00000001952	KHSRP	92	95.058	Monodelphis_domestica
ENSG00000088247	KHSRP	100	74.556	ENSMALG00000006104	khsrp	94	59.429	Monopterus_albus
ENSG00000088247	KHSRP	99	77.976	ENSMALG00000004958	KHSRP	87	66.884	Monopterus_albus
ENSG00000088247	KHSRP	99	100.000	MGP_CAROLIEiJ_G0021800	Khsrp	84	98.469	Mus_caroli
ENSG00000088247	KHSRP	100	100.000	ENSMUSG00000007670	Khsrp	99	98.312	Mus_musculus
ENSG00000088247	KHSRP	100	100.000	MGP_PahariEiJ_G0020789	Khsrp	95	98.172	Mus_pahari
ENSG00000088247	KHSRP	100	100.000	MGP_SPRETEiJ_G0022711	Khsrp	95	98.312	Mus_spretus
ENSG00000088247	KHSRP	100	100.000	ENSMPUG00000006615	KHSRP	99	94.143	Mustela_putorius_furo
ENSG00000088247	KHSRP	100	73.276	ENSMPUG00000010799	-	90	63.084	Mustela_putorius_furo
ENSG00000088247	KHSRP	100	99.408	ENSMLUG00000015543	KHSRP	94	99.522	Myotis_lucifugus
ENSG00000088247	KHSRP	100	100.000	ENSNGAG00000023093	Khsrp	95	96.765	Nannospalax_galili
ENSG00000088247	KHSRP	99	79.882	ENSNBRG00000005876	KHSRP	91	72.425	Neolamprologus_brichardi
ENSG00000088247	KHSRP	100	73.373	ENSNBRG00000023797	khsrp	93	66.878	Neolamprologus_brichardi
ENSG00000088247	KHSRP	99	100.000	ENSNLEG00000015923	KHSRP	99	92.901	Nomascus_leucogenys
ENSG00000088247	KHSRP	100	99.408	ENSMEUG00000016601	KHSRP	100	89.153	Notamacropus_eugenii
ENSG00000088247	KHSRP	100	98.817	ENSOPRG00000010594	-	85	90.982	Ochotona_princeps
ENSG00000088247	KHSRP	100	84.564	ENSODEG00000015021	KHSRP	86	78.571	Octodon_degus
ENSG00000088247	KHSRP	99	79.290	ENSONIG00000002163	KHSRP	93	71.763	Oreochromis_niloticus
ENSG00000088247	KHSRP	100	73.373	ENSONIG00000017713	khsrp	95	66.407	Oreochromis_niloticus
ENSG00000088247	KHSRP	99	91.250	ENSOANG00000000261	KHSRP	92	90.411	Ornithorhynchus_anatinus
ENSG00000088247	KHSRP	100	99.408	ENSOCUG00000026747	-	94	97.484	Oryctolagus_cuniculus
ENSG00000088247	KHSRP	99	64.671	ENSOCUG00000002225	-	94	60.714	Oryctolagus_cuniculus
ENSG00000088247	KHSRP	100	72.189	ENSORLG00000011882	khsrp	93	62.326	Oryzias_latipes
ENSG00000088247	KHSRP	100	67.456	ENSORLG00020005284	khsrp	93	62.205	Oryzias_latipes_hni
ENSG00000088247	KHSRP	100	72.781	ENSORLG00015003791	khsrp	95	63.622	Oryzias_latipes_hsok
ENSG00000088247	KHSRP	100	71.598	ENSOMEG00000013233	khsrp	95	62.835	Oryzias_melastigma
ENSG00000088247	KHSRP	100	100.000	ENSOGAG00000008073	KHSRP	99	99.437	Otolemur_garnettii
ENSG00000088247	KHSRP	100	100.000	ENSOARG00000005881	KHSRP	97	99.174	Ovis_aries
ENSG00000088247	KHSRP	100	100.000	ENSPPAG00000036395	-	94	99.839	Pan_paniscus
ENSG00000088247	KHSRP	100	100.000	ENSPPAG00000036398	-	100	90.127	Pan_paniscus
ENSG00000088247	KHSRP	100	73.276	ENSPPAG00000038243	-	93	61.002	Pan_paniscus
ENSG00000088247	KHSRP	100	100.000	ENSPPRG00000008001	KHSRP	81	91.017	Panthera_pardus
ENSG00000088247	KHSRP	100	100.000	ENSPTRG00000010364	KHSRP	97	94.294	Pan_troglodytes
ENSG00000088247	KHSRP	100	73.276	ENSPTRG00000000888	FUBP1	93	60.850	Pan_troglodytes
ENSG00000088247	KHSRP	100	73.276	ENSPANG00000004797	-	93	61.854	Papio_anubis
ENSG00000088247	KHSRP	100	100.000	ENSPANG00000000103	KHSRP	100	100.000	Papio_anubis
ENSG00000088247	KHSRP	100	77.515	ENSPKIG00000003200	khsrp	87	67.841	Paramormyrops_kingsleyae
ENSG00000088247	KHSRP	99	83.478	ENSPKIG00000005077	KHSRP	92	72.565	Paramormyrops_kingsleyae
ENSG00000088247	KHSRP	98	66.463	ENSPKIG00000009065	-	94	57.277	Paramormyrops_kingsleyae
ENSG00000088247	KHSRP	100	97.633	ENSPSIG00000008244	KHSRP	69	93.933	Pelodiscus_sinensis
ENSG00000088247	KHSRP	98	63.871	ENSPMGG00000016443	khsrp	97	61.189	Periophthalmus_magnuspinnatus
ENSG00000088247	KHSRP	100	100.000	ENSPEMG00000022853	Khsrp	87	94.554	Peromyscus_maniculatus_bairdii
ENSG00000088247	KHSRP	100	99.408	ENSPCIG00000025516	KHSRP	99	96.095	Phascolarctos_cinereus
ENSG00000088247	KHSRP	100	73.276	ENSPCIG00000022984	-	93	62.928	Phascolarctos_cinereus
ENSG00000088247	KHSRP	100	76.923	ENSPFOG00000004577	khsrp	95	66.457	Poecilia_formosa
ENSG00000088247	KHSRP	100	76.923	ENSPLAG00000010763	khsrp	95	66.457	Poecilia_latipinna
ENSG00000088247	KHSRP	100	76.923	ENSPMEG00000014049	khsrp	95	66.457	Poecilia_mexicana
ENSG00000088247	KHSRP	100	76.923	ENSPREG00000000419	khsrp	95	66.038	Poecilia_reticulata
ENSG00000088247	KHSRP	100	86.391	ENSPPYG00000019172	-	95	76.771	Pongo_abelii
ENSG00000088247	KHSRP	100	100.000	ENSPPYG00000009454	KHSRP	98	98.408	Pongo_abelii
ENSG00000088247	KHSRP	99	100.000	ENSPCAG00000000246	KHSRP	100	89.027	Procavia_capensis
ENSG00000088247	KHSRP	100	100.000	ENSPCOG00000027506	KHSRP	100	91.421	Propithecus_coquereli
ENSG00000088247	KHSRP	100	100.000	ENSPVAG00000007251	KHSRP	87	94.364	Pteropus_vampyrus
ENSG00000088247	KHSRP	100	72.781	ENSPNYG00000001374	khsrp	95	64.907	Pundamilia_nyererei
ENSG00000088247	KHSRP	99	79.882	ENSPNYG00000014008	KHSRP	87	71.732	Pundamilia_nyererei
ENSG00000088247	KHSRP	100	81.065	ENSPNAG00000012026	khsrp	93	71.406	Pygocentrus_nattereri
ENSG00000088247	KHSRP	100	100.000	ENSRNOG00000047628	Khsrp	99	98.453	Rattus_norvegicus
ENSG00000088247	KHSRP	97	100.000	ENSRBIG00000041605	KHSRP	96	86.545	Rhinopithecus_bieti
ENSG00000088247	KHSRP	100	100.000	ENSRROG00000031782	KHSRP	92	100.000	Rhinopithecus_roxellana
ENSG00000088247	KHSRP	100	100.000	ENSSBOG00000034871	KHSRP	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000088247	KHSRP	100	99.408	ENSSHAG00000011383	KHSRP	94	98.845	Sarcophilus_harrisii
ENSG00000088247	KHSRP	99	83.478	ENSSFOG00015010767	KHSRP	92	73.071	Scleropages_formosus
ENSG00000088247	KHSRP	100	79.290	ENSSFOG00015018719	khsrp	93	68.770	Scleropages_formosus
ENSG00000088247	KHSRP	99	81.928	ENSSMAG00000012166	KHSRP	90	65.329	Scophthalmus_maximus
ENSG00000088247	KHSRP	100	74.556	ENSSMAG00000004167	khsrp	95	60.731	Scophthalmus_maximus
ENSG00000088247	KHSRP	99	81.739	ENSSDUG00000002110	KHSRP	93	72.770	Seriola_dumerili
ENSG00000088247	KHSRP	100	78.107	ENSSDUG00000002390	khsrp	94	68.038	Seriola_dumerili
ENSG00000088247	KHSRP	99	81.739	ENSSLDG00000025625	KHSRP	93	72.770	Seriola_lalandi_dorsalis
ENSG00000088247	KHSRP	100	70.414	ENSSLDG00000012993	khsrp	94	64.670	Seriola_lalandi_dorsalis
ENSG00000088247	KHSRP	100	97.633	ENSSPUG00000016462	KHSRP	90	92.810	Sphenodon_punctatus
ENSG00000088247	KHSRP	100	78.107	ENSSPAG00000008349	khsrp	95	67.907	Stegastes_partitus
ENSG00000088247	KHSRP	99	80.870	ENSSPAG00000008244	KHSRP	83	73.132	Stegastes_partitus
ENSG00000088247	KHSRP	100	73.276	ENSSSCG00000003771	-	96	60.140	Sus_scrofa
ENSG00000088247	KHSRP	100	100.000	ENSSSCG00000013538	KHSRP	100	99.160	Sus_scrofa
ENSG00000088247	KHSRP	100	72.781	ENSTNIG00000014067	khsrp	94	62.439	Tetraodon_nigroviridis
ENSG00000088247	KHSRP	100	100.000	ENSTTRG00000010390	KHSRP	95	96.429	Tursiops_truncatus
ENSG00000088247	KHSRP	99	99.429	ENSUAMG00000023100	KHSRP	84	98.741	Ursus_americanus
ENSG00000088247	KHSRP	100	73.276	ENSUAMG00000004961	-	96	62.413	Ursus_americanus
ENSG00000088247	KHSRP	99	99.429	ENSUMAG00000011144	KHSRP	85	91.433	Ursus_maritimus
ENSG00000088247	KHSRP	100	73.276	ENSUMAG00000006022	-	93	60.994	Ursus_maritimus
ENSG00000088247	KHSRP	95	100.000	ENSVPAG00000010837	-	100	89.972	Vicugna_pacos
ENSG00000088247	KHSRP	100	73.276	ENSVVUG00000030003	-	93	61.086	Vulpes_vulpes
ENSG00000088247	KHSRP	100	100.000	ENSVVUG00000026737	KHSRP	94	99.470	Vulpes_vulpes
ENSG00000088247	KHSRP	99	91.176	ENSXETG00000021862	khsrp	97	69.350	Xenopus_tropicalis
ENSG00000088247	KHSRP	99	71.257	ENSXETG00000013137	fubp1	95	62.208	Xenopus_tropicalis
ENSG00000088247	KHSRP	100	75.740	ENSXCOG00000014443	khsrp	91	65.798	Xiphophorus_couchianus
ENSG00000088247	KHSRP	100	75.740	ENSXMAG00000012876	khsrp	95	66.299	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000178	exosome (RNase complex)	16126846.	NAS	Component
GO:0000375	RNA splicing, via transesterification reactions	10911989.	TAS	Process
GO:0003677	DNA binding	-	IEA	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	16126846.19458619.	IPI	Function
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006355	regulation of transcription, DNA-templated	-	IEA	Process
GO:0006397	mRNA processing	-	IEA	Process
GO:0006402	mRNA catabolic process	-	IEA	Process
GO:0008380	RNA splicing	10911989.	TAS	Process
GO:0010494	cytoplasmic stress granule	-	IEA	Component
GO:0010586	miRNA metabolic process	27478153.	IMP	Process
GO:0010989	negative regulation of low-density lipoprotein particle clearance	26523989.	IGI	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0035925	mRNA 3'-UTR AU-rich region binding	16126846.	IDA	Function
GO:0043488	regulation of mRNA stability	16126846.	IDA	Process
GO:0043488	regulation of mRNA stability	-	TAS	Process
GO:0045019	negative regulation of nitric oxide biosynthetic process	16126846.	IDA	Process
GO:0051028	mRNA transport	-	IEA	Process
GO:0061014	positive regulation of mRNA catabolic process	16126846.	IDA	Process
GO:0061158	3'-UTR-mediated mRNA destabilization	16126846.	IDA	Process
GO:0071345	cellular response to cytokine stimulus	16126846.	IMP	Process
GO:2000628	regulation of miRNA metabolic process	-	IEA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

PRI

Literatures

Expression

Transcripts

Gene Model

PPI

Paralog

Ortholog

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.